藤原　優子 (フジワラ　ユウコ)

研究者情報

所属

• 薬学部 講師

URL

https://jglobal.jst.go.jp/detail?JGLOBAL_ID=201801004801062532

科研費研究者番号

• 70722320

J-Global ID

• 201801004801062532

研究キーワード

• 先天代謝異常症   リン脂質   糖脂質   

研究分野

• ライフサイエンス / 薬系分析、物理化学

研究活動情報

論文

• Ceramide synthase CERS4 gene downregulation is associated with KRAS mutation in colorectal cancer.

  Tamuro Hayama; Kotaro Hama; Tsuyoshi Ozawa; Yuko Fujiwara; Keijiro Nozawa; Keiji Matsuda; Kazuaki Yokoyama; Yojiro Hashiguchi; Hiroki Ochiai; Takeyuki Misawa; Takeo Fukagawa

  Scientific reports 13 1 16249 - 16249 2023年09月
• Application of LC-ESI-MS/MS in the analysis of lipid species in samples from patients with X-linked adrenoleukodystrophy, a peroxisomal disease

  Kotaro Hama; Yuko Fujiwara; Kazuaki Yokoyama

  Medical Mass Spectrometry 6 2 101 - 111 2022年11月 [査読有り][招待有り]
  
• Controlled Tetradeuteration of Straight-Chain Fatty Acids: Synthesis, Application, and Insight into the Metabolism of Oxidized Linoleic Acid.

  Ayako Watanabe; Kotaro Hama; Kohei Watanabe; Yuko Fujiwara; Kazuaki Yokoyama; Shigeo Murata; Ryo Takita

  Angewandte Chemie (International ed. in English) e202202779  2022年04月
• Glycosphingolipids with Very Long-Chain Fatty Acids Accumulate in Fibroblasts from Adrenoleukodystrophy Patients

  Yuko Fujiwara; Kotaro Hama; Nobuyuki Shimozawa; Kazuaki Yokoyama

  International Journal of Molecular Sciences 22 16 8645 - 8645 2021年08月
• Very long-chain fatty acids are accumulated in triacylglycerol and nonesterified forms in colorectal cancer tissues.

  Kotaro Hama; Yuko Fujiwara; Tamuro Hayama; Tsuyoshi Ozawa; Keijiro Nozawa; Keiji Matsuda; Yojiro Hashiguchi; Kazuaki Yokoyama

  Scientific reports 11 1 6163 - 6163 2021年03月
• Hexacosenoyl-CoA is the most abundant very long-chain acyl-CoA in ATP binding cassette transporter D1-deficient cells.

  Kotaro Hama; Yuko Fujiwara; Shigeo Takashima; Yasuhiro Hayashi; Atsushi Yamashita; Nobuyuki Shimozawa; Kazuaki Yokoyama

  Journal of lipid research 61 4 523 - 536 2020年04月 [査読有り]
  
• Mass spectrometry in combination with a chiral column and multichannel-MRM allows comprehensive analysis of glycosphingolipid molecular species from mouse brain.

  Yuko Fujiwara; Kotaro Hama; Kazuaki Yokoyama

  Carbohydrate research 490 107959 - 107959 2020年02月 [査読有り]
  
• Quantitative and Qualitative Method for Sphingomyelin by LC-MS Using Two Stable Isotopically Labeled Sphingomyelin Species.

  Kotaro Hama; Yuko Fujiwara; Kazuaki Yokoyama

  Journal of visualized experiments : JoVE 135 2018年05月 [査読有り]
  
• Profiling and Imaging of Phospholipids in Brains of Abcd1-Deficient Mice.

  Hama K; Fujiwara Y; Morita M; Yamazaki F; Nakashima Y; Takei S; Takashima S; Setou M; Shimozawa N; Imanaka T; Yokoyama K

  Lipids 53 1 85 - 102 2018年01月 [査読有り]
  
• Acyl Chain Preference in Foam Cell Formation from Mouse Peritoneal Macrophages.

  Yuko Fujiwara; Kotaro Hama; Makoto Tsukahara; Ryosuke Izumi-Tsuzuki; Toru Nagai; Mihoko Ohe-Yamada; Keizo Inoue; Kazuaki Yokoyama

  Biological & pharmaceutical bulletin 41 1 86 - 91 2018年 [査読有り]
  
• Comprehensive Quantitation Using Two Stable Isotopically Labeled Species and Direct Detection of N-Acyl Moiety of Sphingomyelin

  Kotaro Hama; Yuko Fujiwara; Hidetsugu Tabata; Hideyo Takahashi; Kazuaki Yokoyama

  LIPIDS 52 9 789 - 799 2017年09月 [査読有り]
  
• Combined Mitigation of the Gastrointestinal and Hematopoietic Acute Radiation Syndromes by an LPA(2) Receptor-Specific Nonlipid Agonist

  Renukadevi Patil; Erzsebet Szabo; James I. Fells; Andrea Balogh; Keng G. Lim; Yuko Fujiwara; Derek D. Norman; Sue-Chin Lee; Louisa Balazs; Fridtjof Thomas; Shivaputra Patil; Karin Emmons-Thompson; Alyssa Boler; Jur Strobos; Shannon W. McCool; C. Ryan Yates; Jennifer Stabenow; Gerrald I. Byrne; Duane D. Miller; Gabor J. Tigyi

  CHEMISTRY & BIOLOGY 22 2 206 - 216 2015年02月 [査読有り]
  
• Autotaxin and LPA(1) and LPA(5) Receptors Exert Disparate Functions in Tumor Cells versus the Host Tissue Microenvironment in Melanoma Invasion and Metastasis

  Sue-Chin Lee; Yuko Fujiwara; Jianxiong Liu; Junming Yue; Yoshibumi Shimizu; Derek D. Norman; Yaohong Wang; Ryoko Tsukahara; Erzsebet Szabo; Renukadevi Patil; Souvik Banerjee; Duane D. Miller; Louisa Balazs; Manik C. Ghosh; Christopher M. Waters; Tamas Oravecz; Gabor J. Tigyi

  MOLECULAR CANCER RESEARCH 13 1 174 - 185 2015年01月 [査読有り]
  
• Uncovering unique roles of LPA receptors in the tumor microenvironment.

  Lee SC; Fujiwara Y; Tigyi GJ

  Receptors & clinical investigation 2 1 2015年 [査読有り]
  
• Lysophosphatidic Acid Receptor 5 Inhibits B Cell Antigen Receptor Signaling and Antibody Response

  Jiancheng Hu; Shannon K. Oda; Kristin Shotts; Erin E. Donovan; Pamela Strauch; Lindsey M. Pujanauski; Francisco Victorino; Amin Al-Shami; Yuko Fujiwara; Gabor Tigyi; Tamas Oravecz; Roberta Pelanda; Raul M. Torres

  JOURNAL OF IMMUNOLOGY 193 1 85 - 95 2014年07月 [査読有り]
  
• Lysophosphatidic Acid Inhibits CD8 T-cell Activation and Control of Tumor Progression

  Shannon K. Oda; Pamela Strauch; Yuko Fujiwara; Amin Al-Shami; Tamas Oravecz; Gabor Tigyi; Roberta Pelanda; Raul M. Torres

  CANCER IMMUNOLOGY RESEARCH 1 4 245 - 255 2013年10月 [査読有り]
  
• Hits of a High-Throughput Screen Identify the Hydrophobic Pocket of Autotaxin/Lysophospholipase D As an Inhibitory Surface

  James I. Fells; Sue Chin Lee; Yuko Fujiwara; Derek D. Norman; Keng Gat Lim; Ryoko Tsukahara; Jianxiong Liu; Renukadevi Patil; Duane D. Miller; R. Jason Kirby; Sandra Nelson; William Seibel; Ruben Papoian; Abby L. Parrill; Daniel L. Baker; Robert Bittman; Gabor Tigyi

  MOLECULAR PHARMACOLOGY 84 3 415 - 424 2013年09月 [査読有り]
  
• Mitigation of radiation injury by selective stimulation of the LPA(2) receptor.

  Kiss GN; Lee SC; Fells JI; Liu J; Valentine WJ; Fujiwara Y; Thompson KE; Yates CR; Sümegi B; Tigyi G

  Biochimica et biophysica acta 1831 1 117 - 125 2013年01月 [査読有り]
  
• Controlling cancer through the autotaxin–lysophosphatidic acid receptor axis

  Mari GOTOH; Yuko FUJIWARA; Junming YUE; Jianxiong LIU; SueChin LEE; James FELLS; Ayako UCHIYAMA; Kimiko MURAKAMI-MUROFUSHI; Stephen KENNEL; Jonathan WALL; Renukadevi PATIL; Renuka GUPTE; Louisa BALAZS; Duane D. MILLER; Gabor J. TIGYI

  Bioorg. Med. Chem. Lett. 40 1 31 - 36 2012年02月 [査読有り]
  
• FTY720 (Gilenya) Phosphate Selectivity of Sphingosine 1-Phosphate Receptor Subtype 1 (S1P(1)) G Protein-coupled Receptor Requires Motifs in Intracellular Loop 1 and Transmembrane Domain 2

  William J. Valentine; Virginia I. Godwin; Daniel A. Osborne; Jianxiong Liu; Yuko Fujiwara; James Van Brocklyn; Robert Bittman; Abby L. Parrill; Gabor Tigyi

  JOURNAL OF BIOLOGICAL CHEMISTRY 286 35 30513 - 30525 2011年09月 [査読有り]
  
• Benzyl and Naphthalene Methylphosphonic Acid Inhibitors of Autotaxin with Anti-invasive and Anti-metastatic Activity

  Renuka Gupte; Renukadevi Patil; Jianxiong Liu; Yaohong Wang; Sue C. Lee; Yuko Fujiwara; James Fells; Alyssa L. Bolen; Karin Emmons-Thompson; C. Ryan Yates; Anjaih Siddam; Nattapon Panupinthu; Truc-Chi T. Pham; Daniel L. Baker; Abby L. Parrill; Gordon B. Mills; Gabor Tigyi; Duane D. Miller

  CHEMMEDCHEM 6 5 922 - 935 2011年05月 [査読有り]
  
• Synthesis and pharmacological evaluation of the stereoisomers of 3-carba cyclic-phosphatidic acid

  Renuka Gupte; Anjaih Siddam; Yan Lu; Wei Li; Yuko Fujiwara; Nattapon Panupinthu; Truc-Chi Pham; Daniel L. Baker; Abby L. Parrill; Mari Gotoh; Kimiko Murakami-Murofushi; Susumu Kobayashi; Gordon B. Mills; Gabor Tigyi; Duane D. Miller

  BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 20 24 7525 - 7528 2010年12月 [査読有り]
  
• Sphingosine 1-Phosphate Receptor 4 Uses HER2 (ERBB2) to Regulate Extracellular Signal Regulated Kinase-1/2 in MDA-MB-453 Breast Cancer Cells

  Jaclyn S. Long; Yuko Fujiwara; Joanne Edwards; Claire L. Tannahill; Gabor Tigyi; Susan Pyne; Nigel J. Pyne

  JOURNAL OF BIOLOGICAL CHEMISTRY 285 46 35957 - 35966 2010年11月 [査読有り]
  
• Phospholipase D2-Dependent Inhibition of the Nuclear Hormone Receptor PPAR gamma by Cyclic Phosphatidic Acid

  Tamotsu Tsukahara; Ryoko Tsukahara; Yuko Fujiwara; Junming Yue; Yunhui Cheng; Huazhang Guo; Alyssa Bolen; Chunxiang Zhang; Louisa Balazs; Fabio Re; Guangwei Du; Michael A. Frohman; Daniel L. Baker; Abby L. Parrill; Ayako Uchiyama; Tetsuyuki Kobayashi; Kimiko Murakami-Murofushi; Gabor Tigyi

  MOLECULAR CELL 39 3 421 - 432 2010年08月 [査読有り]
  
• Dual Activity Lysophosphatidic Acid Receptor Pan-Antagonist/Autotaxin Inhibitor Reduces Breast Cancer Cell Migration In vitro and Causes Tumor Regression In vivo

  Honglu Zhang; Xiaoyu Xu; Joanna Gajewiak; Ryoko Tsukahara; Yuko Fujiwara; Jianxiong Liu; James I. Fells; Donna Perygin; Abby L. Parrill; Gabor Tigyi; Glenn D. Prestwich

  CANCER RESEARCH 69 13 5441 - 5449 2009年07月 [査読有り]
  
• Unique Ligand Selectivity of the GPR92/LPA(5) Lysophosphatidate Receptor Indicates Role in Human Platelet Activation

  Jesica R. Williams; Anna L. Khandoga; Pankaj Goyal; James I. Fells; Donna H. Perygin; Wolfgang Siess; Abby L. Parrill; Gabor Tigyi; Yuko Fujiwara

  JOURNAL OF BIOLOGICAL CHEMISTRY 284 25 17304 - 17319 2009年06月 [査読有り]
  
• Lysophosphatidic acid 2 receptor-mediated supramolecular complex formation regulates its antiapoptotic effect.

  Shuyu E; Yun-Ju Lai; Ryoko Tsukahara; Chen-Shan Chen; Yuko Fujiwara; Junming Yue; Jei-Hwa Yu; Huazhang Guo; Akio Kihara; Gábor Tigyi; Fang-Tsyr Lin

  The Journal of biological chemistry 284 21 14558 - 71 2009年05月 [査読有り]
  
• Cyclic phosphatidic acid - a unique bioactive phospholipid.

  Fujiwara Y

  Biochimica et biophysica acta 1781 9 519 - 524 2008年09月 [査読有り]
  
• Identification of non-lipid LPA(3) antagonists by virtual screening

  James I. Fells; Ryoko Tsukahara; Yuko Fujiwara; Jianxiong Liu; Donna H. Perygin; Daniel A. Osborne; Gabor Tigyi; Abby L. Parrill

  BIOORGANIC & MEDICINAL CHEMISTRY 16 11 6207 - 6217 2008年06月 [査読有り]
  
• Subtype-specific residues involved in ligand activation of the endothelial differentiation gene family lysophosphatidic acid receptors

  William J. Valentine; James I. Fells; Donna H. Perygin; Sana Mujahid; Kazuaki Yokoyama; Yuko Fujiwara; Ryoko Tsukahara; James R. Van Brocklyn; Abby L. Parrill; Gabor Tigyi

  JOURNAL OF BIOLOGICAL CHEMISTRY 283 18 12175 - 12187 2008年05月 [査読有り]
  
• Lysophospholipid signaling: Beyond the EDGs

  William J. Valentine; Yuko Fujiwara; Ryoko Tsukahara; Gabor Tigyi

  BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1780 3 597 - 605 2008年03月 [査読有り]
  
• Lysophospholipid signaling: beyond the EDGs.

  Valentine WJ; Fujiwara Y; Tsukahara R; Tigyi G

  Biochimica et biophysica acta 1780 3 597 - 605 2008年03月 [査読有り]
  
• Synthesis, pharmacology, and cell biology of sn-2-aminooxy analogues of lysophosphatidic acid

  Joanna Gajewiak; Ryoko Tsukahara; Yuko Fujiwara; Gabor Tigyi; Glenn D. Prestwich

  ORGANIC LETTERS 10 6 1111 - 1114 2008年03月 [査読有り]
  
• Alkoxymethylenephosphonate analogues of (Lyso)phosphatidic acid stimulate signaling networks coupled to the LPA(2) receptor

  Joanna Gajewiak; Ryoko Tsukahara; Tamotsu Tsukahara; Yuko Fujiwara; Shuanxing Yu; Wing Lu; Mandi Murph; Gordon B. Mills; Gabor Tigyi; Gleen D. Prestwich

  CHEMMEDCHEM 2 12 1789 - 1798 2007年12月 [査読有り]
  
• alpha-substituted phosphonate analogues of lysophosphatidic acid (LPA) selectively inhibit production and action of LPA

  Guowei Jiang; Yong Xu; Yuko Fujiwara; Tamotsu Tsukahara; Ryoko Tsukahara; Joanna Gajewiak; Gabor Tigyi; Glenn D. Prestwich

  CHEMMEDCHEM 2 5 679 - 690 2007年05月 [査読有り]
  
• Inhibition of transcellular tumor cell migration and metastasis by novel carba-derivatives of cyclic phosphatidic acid

  Ayako Uchiyama; Mutsuko Mukai; Yuko Fujiwara; Susumu Kobayashi; Nobuyuki Kawai; Hiromu Murofushi; Masahiro Inoue; Shigenori Enoki; Yuichiro Tanaka; Tamotsu Niki; Tetsuyuki Kobayashi; Gabor Tigyi; Kimiko Murakami-Murofushi

  BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS 1771 1 103 - 112 2007年01月 [査読有り]
  
• Identification of the hydrophobic ligand binding pocket of the S1P(1) receptor

  Yuko Fujiwara; Daniel A. Osborne; Michelle D. Walker; De-an Wang; Debra A. Bautista; Karoly Liliom; James R. Van Brocklyn; Abby L. Parrill; Gabor Tigyi

  JOURNAL OF BIOLOGICAL CHEMISTRY 282 4 2374 - 2385 2007年01月 [査読有り]
  
• Inhibition of transcellular tumor cell migration and metastasis by novel carba-derivatives of cyclic phosphatidic acid.

  Uchiyama A; Mukai M; Fujiwara Y; Kobayashi S; Kawai N; Murofushi H; Inoue M; Enoki S; Tanaka Y; Niki T; Kobayashi T; Tigyi G; Murakami-Murofushi K

  Biochimica et biophysica acta 1771 1 103 - 112 2007年01月 [査読有り]
  
• Carba analogs of cyclic phosphatidic acid are selective inhibitors of autotaxin and cancer cell invasion and metastasis

  Daniel L. Baker; Yuko Fujiwara; Kathryn R. Pigg; Ryoko Tsukahara; Susumu Kobayashi; Hiromu Murofushi; Ayako Uchiyama; Kimiko Murakami-Murofushi; Eunjin Koh; Russell W. Bandle; Hoe-Sup Byun; Robert Bittman; Dominic Fan; Mandi Murph; Gordon B. Mills; Gabor Tigyi

  JOURNAL OF BIOLOGICAL CHEMISTRY 281 32 22786 - 22793 2006年08月 [査読有り]
  
• Phosphonothioate and fluoromethylene phosphonate analogues of cyclic phosphatidic acid: Novel antagonists of lysophosphatidic acid receptors

  Yong Xu; Guowei Jiang; Ryoko Tsukahara; Yuko Fujiwara; Gabor Tigyi; Glenn D. Prestwich

  JOURNAL OF MEDICINAL CHEMISTRY 49 17 5309 - 5315 2006年08月 [査読有り]
  
• Serine phosphorylation differentially affects RhoA binding to effectors: Implications to NGF-induced neurite outgrowth

  N Nusser; E Gosmanova; N Makarova; Y Fujiwara; L Yang; FK Guo; YN Luo; Y Zheng; G Tigyi

  CELLULAR SIGNALLING 18 5 704 - 714 2006年05月 [査読有り]
  
• Cell migration activated by platelet-derived growth factor receptor is blocked by an inverse agonist of the sphingosine 1-phosphate receptor-1.

  Waters CM; Long J; Gorshkova I; Fujiwara Y; Connell M; Belmonte KE; Tigyi G; Natarajan V; Pyne S; Pyne NJ

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20 3 509 - 511 2006年03月 [査読有り]
  
• Phosphorothioate analogues of alkyl lysophosphaticlic acid as LPA(3) receptor-selective agonists

  Lian Qian; Yong Xu; Ted Simper; Guowei Jiang; Junken Aoki; Makiko Umezu-Goto; Hiroyuki Arai; Shuangxing Yu; Gordon B. Mills; Ryoko Tsukahara; Natalia Makarova; Yuko Fujiwara; Gabor Tigyi; Glenn D. Prestwich

  CHEMMEDCHEM 1 3 376 - 383 2006年03月 [査読有り]
  
• Synthesis and pharmacological evaluation of second-generation phosphatidic acid derivatives as lysophosphatidic acid receptor ligands

  GG Durgam; R Tsukahara; N Makarova; MD Walker; Y Fujiwara; KR Pigg; DL Baker; VM Sardar; AL Parrill; G Tigyi; DD Miller

  BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 16 3 633 - 640 2006年02月 [査読有り]
  
• Identification of Darmstoff analogs as selective agonists and antagonists of lysophosphatidic acid receptors

  Gududuru, V; K Zeng; R Tsukahara; N Makarova; Y Fujiwara; KR Pigg; DL Baker; G Tigyi; DD Miller

  BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 16 2 451 - 456 2006年01月 [査読有り]
  
• Identification of residues responsible for ligand recognition and regioisomeric selectivity of lysophosphatidic acid receptors expressed in mammalian cells

  Y Fujiwara; Sardar, V; A Tokumura; D Baker; K Murakami-Murofushi; A Parrill; G Tigyi

  JOURNAL OF BIOLOGICAL CHEMISTRY 280 41 35038 - 35050 2005年10月 [査読有り]
  
• Lysophosphatidic acid inhibits cholera toxin-induced secretory diarrhea through CFTR-dependent protein interactions

  CY Li; KS Dandridge; A Di; KL Marrs; EL Harris; K Roy; JS Jackson; NV Makarova; Y Fujiwara; PL Farrar; DJ Nelson; GJ Tigyi; AP Naren

  JOURNAL OF EXPERIMENTAL MEDICINE 202 7 975 - 986 2005年10月 [査読有り]
  
• Sphingosine 1-phosphate analogue recognition and selectivity at S1P(4) within the endothelial differentiation gene family of receptors

  Y Inagaki; TT Pham; Y Fujiwara; T Kohno; DA Osborne; Y Igarashi; G Tigyi; AL Parrill

  BIOCHEMICAL JOURNAL 389 Pt 1 187 - 195 2005年07月 [査読有り]
  
• Cyclic phosphatidic acid elicits neurotrophin-like actions in embryonic hippocampal neurons

  Y Fujiwara; A Sebok; S Meakin; T Kobayashi; K Murakami-Murofushi; G Tigyi

  JOURNAL OF NEUROCHEMISTRY 87 5 1272 - 1283 2003年12月 [査読有り]
  
• Biological functions of a novel lipid mediator, cyclic phosphatidic acid.

  Murakami-Murofushi K; Uchiyama A; Fujiwara Y; Kobayashi T; Kobayashi S; Mukai M; Murofushi H; Tigyi G

  Biochimica et biophysica acta 1582 1-3 1 - 7 2002年05月 [査読有り]
  

MISC

• 大腸がん組織中に蓄積する極長鎖脂肪酸の解析

  濱 弘太郎; 藤原 優子; 端山 軍; 小澤 毅士; 金子 建介; 橋口 陽二郎; 横山 和明 日本生化学会大会プログラム・講演要旨集 94回 108 -108 2021年11月
• Abcd1ノックアウトマウスの脳のスフィンゴミエリン分子種の解析

  濱 弘太郎; 藤原 優子; 守田 雅志; 今中 常雄; 下澤 伸行; 横山 和明 日本生化学会大会プログラム・講演要旨集 89回 [1P -062] 2016年09月
• Abcd1ノックアウトマウスの脳のスフィンゴミエリン分子種の解析

  濱 弘太郎; 藤原 優子; 守田 雅志; 今中 常雄; 下澤 伸行; 横山 和明 JSBMS Letters 41 (Suppl.) 70 -70 2016年08月
• Abcd1ノックアウトマウスの脳のスフィンゴミエリン分子種の解析

  濱 弘太郎; 藤原 優子; 守田 雅志; 今中 常雄; 下澤 伸行; 横山 和明 脂質生化学研究 58 97 -98 2016年05月
• ESI-LC/MSを用いたAbcd1ノックアウトマウスの脳のリン脂質解析

  濱 弘太郎; 藤原 優子; 守田 雅志; 今中 常雄; 下澤 伸行; 横山 和明 日本先天代謝異常学会雑誌 31 189 -189 2015年10月
• abcd1ノックアウトマウスの脳のリン脂質解析

  濱 弘太郎; 藤原 優子; 守田 雅志; 今中 常雄; 下澤 伸行; 横山 和明 JSBMS Letters 40 (Suppl.) 84 -84 2015年08月
• 多段階MRMモードを用いたAbcd1ノックアウトマウスの脳の脂質解析

  濱 弘太郎; 藤原 優子; 松本 隼; 守田 雅志; 今中 常雄; 下澤 伸行; 横山 和明 脂質生化学研究 57 144 -145 2015年05月
• LC/MSによるリン脂質分子種別の網羅的解析方法の樹立(ALDにおける病型診断バイオマーカーの発見を目指して)

  濱 弘太郎; 藤原 優子; 今中 常雄; 下澤 伸行 日本先天代謝異常学会雑誌 30 186 -186 2014年10月
• 副腎白質ジストロフィー患者血漿中リン脂質の網羅的解析

  濱 弘太郎; 藤原 優子; 今中 常雄; 下澤 伸行; 横山 和明 日本生化学会大会プログラム・講演要旨集 87回 [2P -045] 2014年10月
• BIOL 50-Optimization of the LPA5 receptor model for therapeutic lead discovery

  Jesica R. Williams; Yuko Fujiwara; Gabor Tigyi; Soujanya Balasankoula; Abby L. Parrill ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 236 2008年08月
• Modeling and mutagenesis of the mouse S1P4 receptor.

  TC Pham; Y Inagaki; Y Igarashi; Y Fujiwara; G Tigyi; AL Parrill ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 227 U910 -U910 2004年03月

共同研究・競争的資金等の研究課題

• スフィンゴ糖脂質分析法の確立がもたらす副腎白質ジストロフィーの病態解明

  日本学術振興会：科学研究費助成事業 基盤研究(C)

  研究期間 : 2022年04月 -2026年03月 

  代表者 : 藤原 優子
• 質量分析を用いたスフィンゴ糖脂質定量解析法の構築

  私学事業団：2019年度 学術研究振興資金 女性研究者奨励金

  研究期間 : 2019年04月 -2020年03月 

  代表者 : 藤原優子
• 質量分析を用いた糖脂質解析法の確立と先天性代謝異常症の診断への臨床応用

  日本学術振興会：科学研究費助成事業

  研究期間 : 2015年04月 -2018年03月 

  代表者 : 藤原 優子
• 基盤研究C

  日本学術振興会：科学研究費助成事業

  研究期間 : 2015年04月 -2018年03月 

  代表者 : 藤原優子
• Beginning Grant-in-Aid

  American Heart Association：

  研究期間 : 2009年07月 -2011年06月 

  代表者 : 藤原優子
• Postdoctoral Fellowship

  American Heart Association：

  研究期間 : 2006年07月 -2008年06月 

  代表者 : 藤原優子