Fujiwara Yuko

Researcher Information

Affiliation

Faculty of Pharmaceutical Sciences Senior Assistant Professor
Graduate School of Pharmaceutical Sciences Senior Assistant Professor

URL

https://jglobal.jst.go.jp/detail?JGLOBAL_ID=201801004801062532

Research funding number

• 70722320

J-Global ID

• 201801004801062532

Research Interests

• 先天代謝異常症   リン脂質   糖脂質   

Research Areas

• Life sciences / Pharmaceuticals - analytical and physicochemistry

Research Activity Information

Published Papers

• Ceramide synthase CERS4 gene downregulation is associated with KRAS mutation in colorectal cancer.

  Tamuro Hayama; Kotaro Hama; Tsuyoshi Ozawa; Yuko Fujiwara; Keijiro Nozawa; Keiji Matsuda; Kazuaki Yokoyama; Yojiro Hashiguchi; Hiroki Ochiai; Takeyuki Misawa; Takeo Fukagawa

  Scientific reports 13 (1) 16249 - 16249 2023/09
• Application of LC-ESI-MS/MS in the analysis of lipid species in samples from patients with X-linked adrenoleukodystrophy, a peroxisomal disease

  Kotaro Hama; Yuko Fujiwara; Kazuaki Yokoyama

  Medical Mass Spectrometry 6 (2) 101 - 111 2022/11 [Refereed][Invited]
  
• Controlled Tetradeuteration of Straight-Chain Fatty Acids: Synthesis, Application, and Insight into the Metabolism of Oxidized Linoleic Acid.

  Ayako Watanabe; Kotaro Hama; Kohei Watanabe; Yuko Fujiwara; Kazuaki Yokoyama; Shigeo Murata; Ryo Takita

  Angewandte Chemie (International ed. in English) e202202779  2022/04
• Glycosphingolipids with Very Long-Chain Fatty Acids Accumulate in Fibroblasts from Adrenoleukodystrophy Patients

  Yuko Fujiwara; Kotaro Hama; Nobuyuki Shimozawa; Kazuaki Yokoyama

  International Journal of Molecular Sciences MDPI AG 22 (16) 8645 - 8645 2021/08
• Very long-chain fatty acids are accumulated in triacylglycerol and nonesterified forms in colorectal cancer tissues.

  Kotaro Hama; Yuko Fujiwara; Tamuro Hayama; Tsuyoshi Ozawa; Keijiro Nozawa; Keiji Matsuda; Yojiro Hashiguchi; Kazuaki Yokoyama

  Scientific reports 11 (1) 6163 - 6163 2021/03
• Hexacosenoyl-CoA is the most abundant very long-chain acyl-CoA in ATP binding cassette transporter D1-deficient cells.

  Kotaro Hama; Yuko Fujiwara; Shigeo Takashima; Yasuhiro Hayashi; Atsushi Yamashita; Nobuyuki Shimozawa; Kazuaki Yokoyama

  Journal of lipid research 61 (4) 523 - 536 2020/04 [Refereed]
  
• Mass spectrometry in combination with a chiral column and multichannel-MRM allows comprehensive analysis of glycosphingolipid molecular species from mouse brain.

  Yuko Fujiwara; Kotaro Hama; Kazuaki Yokoyama

  Carbohydrate research 490 107959 - 107959 2020/02 [Refereed]
  
• Lipidomics of peroxisomal disorders

  Kotaro Hama; Yuko Fujiwara; Kazuaki Yokoyama

  Peroxisomes: Biogenesis, Function, and Role in Human Disease Springer Singapore 249 - 260 2020/01
• Quantitative and Qualitative Method for Sphingomyelin by LC-MS Using Two Stable Isotopically Labeled Sphingomyelin Species.

  Kotaro Hama; Yuko Fujiwara; Kazuaki Yokoyama

  Journal of visualized experiments : JoVE (135) 2018/05 [Refereed]
  
• Profiling and Imaging of Phospholipids in Brains of Abcd1-Deficient Mice.

  Kotaro Hama; Yuko Fujiwara; Masashi Morita; Fumiyoshi Yamazaki; Yuko Nakashima; Shiro Takei; Shigeo Takashima; Mitsutoshi Setou; Nobuyuki Shimozawa; Tsuneo Imanaka; Kazuaki Yokoyama

  Lipids 53 (1) 85 - 102 0024-4201 2018/01 [Refereed]
  
• Acyl Chain Preference in Foam Cell Formation from Mouse Peritoneal Macrophages.

  Yuko Fujiwara; Kotaro Hama; Makoto Tsukahara; Ryosuke Izumi-Tsuzuki; Toru Nagai; Mihoko Ohe-Yamada; Keizo Inoue; Kazuaki Yokoyama

  Biological & pharmaceutical bulletin 41 (1) 86 - 91 0918-6158 2018 [Refereed]
  
• Comprehensive Quantitation Using Two Stable Isotopically Labeled Species and Direct Detection of N-Acyl Moiety of Sphingomyelin

  Kotaro Hama; Yuko Fujiwara; Hidetsugu Tabata; Hideyo Takahashi; Kazuaki Yokoyama

  LIPIDS 52 (9) 789 - 799 0024-4201 2017/09 [Refereed]
  
• Combined Mitigation of the Gastrointestinal and Hematopoietic Acute Radiation Syndromes by an LPA(2) Receptor-Specific Nonlipid Agonist

  Renukadevi Patil; Erzsebet Szabo; James I. Fells; Andrea Balogh; Keng G. Lim; Yuko Fujiwara; Derek D. Norman; Sue-Chin Lee; Louisa Balazs; Fridtjof Thomas; Shivaputra Patil; Karin Emmons-Thompson; Alyssa Boler; Jur Strobos; Shannon W. McCool; C. Ryan Yates; Jennifer Stabenow; Gerrald I. Byrne; Duane D. Miller; Gabor J. Tigyi

  CHEMISTRY & BIOLOGY 22 (2) 206 - 216 1074-5521 2015/02 [Refereed]
  
• Autotaxin and LPA(1) and LPA(5) Receptors Exert Disparate Functions in Tumor Cells versus the Host Tissue Microenvironment in Melanoma Invasion and Metastasis

  Sue-Chin Lee; Yuko Fujiwara; Jianxiong Liu; Junming Yue; Yoshibumi Shimizu; Derek D. Norman; Yaohong Wang; Ryoko Tsukahara; Erzsebet Szabo; Renukadevi Patil; Souvik Banerjee; Duane D. Miller; Louisa Balazs; Manik C. Ghosh; Christopher M. Waters; Tamas Oravecz; Gabor J. Tigyi

  MOLECULAR CANCER RESEARCH 13 (1) 174 - 185 1541-7786 2015/01 [Refereed]
  
• Uncovering unique roles of LPA receptors in the tumor microenvironment.

  Lee SC; Fujiwara Y; Tigyi GJ

  Receptors & clinical investigation 2 (1) 2330-0558 2015 [Refereed]
  
• Lysophosphatidic Acid Receptor 5 Inhibits B Cell Antigen Receptor Signaling and Antibody Response

  Jiancheng Hu; Shannon K. Oda; Kristin Shotts; Erin E. Donovan; Pamela Strauch; Lindsey M. Pujanauski; Francisco Victorino; Amin Al-Shami; Yuko Fujiwara; Gabor Tigyi; Tamas Oravecz; Roberta Pelanda; Raul M. Torres

  JOURNAL OF IMMUNOLOGY 193 (1) 85 - 95 0022-1767 2014/07 [Refereed]
  
• Lysophosphatidic Acid Inhibits CD8 T-cell Activation and Control of Tumor Progression

  Shannon K. Oda; Pamela Strauch; Yuko Fujiwara; Amin Al-Shami; Tamas Oravecz; Gabor Tigyi; Roberta Pelanda; Raul M. Torres

  CANCER IMMUNOLOGY RESEARCH 1 (4) 245 - 255 2326-6066 2013/10 [Refereed]
  
• Hits of a High-Throughput Screen Identify the Hydrophobic Pocket of Autotaxin/Lysophospholipase D As an Inhibitory Surface

  James I. Fells; Sue Chin Lee; Yuko Fujiwara; Derek D. Norman; Keng Gat Lim; Ryoko Tsukahara; Jianxiong Liu; Renukadevi Patil; Duane D. Miller; R. Jason Kirby; Sandra Nelson; William Seibel; Ruben Papoian; Abby L. Parrill; Daniel L. Baker; Robert Bittman; Gabor Tigyi

  MOLECULAR PHARMACOLOGY 84 (3) 415 - 424 0026-895X 2013/09 [Refereed]
  
• Mitigation of radiation injury by selective stimulation of the LPA(2) receptor.

  Kiss GN; Lee SC; Fells JI; Liu J; Valentine WJ; Fujiwara Y; Thompson KE; Yates CR; Sümegi B; Tigyi G

  Biochimica et biophysica acta 1831 (1) 117 - 125 0006-3002 2013/01 [Refereed]
  
• Controlling cancer through the autotaxin-lysophosphatidic acid receptor axis

  Mari Gotoh; Yuko Fujiwara; Junming Yue; Jianxiong Liu; SueChin Lee; James Fells; Ayako Uchiyama; Kimiko Murakami-Murofushi; Stephen Kennel; Jonathan Wall; Renukadevi Patil; Renuka Gupte; Louisa Balazs; Duane D. Miller; Gabor J. Tigyi

  BIOCHEMICAL SOCIETY TRANSACTIONS 40 (1) 31 - 36 0300-5127 2012/02 [Refereed]
  
• FTY720 (Gilenya) Phosphate Selectivity of Sphingosine 1-Phosphate Receptor Subtype 1 (S1P(1)) G Protein-coupled Receptor Requires Motifs in Intracellular Loop 1 and Transmembrane Domain 2

  William J. Valentine; Virginia I. Godwin; Daniel A. Osborne; Jianxiong Liu; Yuko Fujiwara; James Van Brocklyn; Robert Bittman; Abby L. Parrill; Gabor Tigyi

  JOURNAL OF BIOLOGICAL CHEMISTRY 286 (35) 30513 - 30525 0021-9258 2011/09 [Refereed]
  
• Benzyl and Naphthalene Methylphosphonic Acid Inhibitors of Autotaxin with Anti-invasive and Anti-metastatic Activity

  Renuka Gupte; Renukadevi Patil; Jianxiong Liu; Yaohong Wang; Sue C. Lee; Yuko Fujiwara; James Fells; Alyssa L. Bolen; Karin Emmons-Thompson; C. Ryan Yates; Anjaih Siddam; Nattapon Panupinthu; Truc-Chi T. Pham; Daniel L. Baker; Abby L. Parrill; Gordon B. Mills; Gabor Tigyi; Duane D. Miller

  CHEMMEDCHEM 6 (5) 922 - 935 1860-7179 2011/05 [Refereed]
  
• Synthesis and pharmacological evaluation of the stereoisomers of 3-carba cyclic-phosphatidic acid

  Renuka Gupte; Anjaih Siddam; Yan Lu; Wei Li; Yuko Fujiwara; Nattapon Panupinthu; Truc-Chi Pham; Daniel L. Baker; Abby L. Parrill; Mari Gotoh; Kimiko Murakami-Murofushi; Susumu Kobayashi; Gordon B. Mills; Gabor Tigyi; Duane D. Miller

  BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 20 (24) 7525 - 7528 0960-894X 2010/12 [Refereed]
  
• Sphingosine 1-Phosphate Receptor 4 Uses HER2 (ERBB2) to Regulate Extracellular Signal Regulated Kinase-1/2 in MDA-MB-453 Breast Cancer Cells

  Jaclyn S. Long; Yuko Fujiwara; Joanne Edwards; Claire L. Tannahill; Gabor Tigyi; Susan Pyne; Nigel J. Pyne

  JOURNAL OF BIOLOGICAL CHEMISTRY 285 (46) 35957 - 35966 0021-9258 2010/11 [Refereed]
  
• Phospholipase D2-Dependent Inhibition of the Nuclear Hormone Receptor PPAR gamma by Cyclic Phosphatidic Acid

  Tamotsu Tsukahara; Ryoko Tsukahara; Yuko Fujiwara; Junming Yue; Yunhui Cheng; Huazhang Guo; Alyssa Bolen; Chunxiang Zhang; Louisa Balazs; Fabio Re; Guangwei Du; Michael A. Frohman; Daniel L. Baker; Abby L. Parrill; Ayako Uchiyama; Tetsuyuki Kobayashi; Kimiko Murakami-Murofushi; Gabor Tigyi

  MOLECULAR CELL 39 (3) 421 - 432 1097-2765 2010/08 [Refereed]
  
• Dual Activity Lysophosphatidic Acid Receptor Pan-Antagonist/Autotaxin Inhibitor Reduces Breast Cancer Cell Migration In vitro and Causes Tumor Regression In vivo

  Honglu Zhang; Xiaoyu Xu; Joanna Gajewiak; Ryoko Tsukahara; Yuko Fujiwara; Jianxiong Liu; James I. Fells; Donna Perygin; Abby L. Parrill; Gabor Tigyi; Glenn D. Prestwich

  CANCER RESEARCH 69 (13) 5441 - 5449 0008-5472 2009/07 [Refereed]
  
• Unique Ligand Selectivity of the GPR92/LPA(5) Lysophosphatidate Receptor Indicates Role in Human Platelet Activation

  Jesica R. Williams; Anna L. Khandoga; Pankaj Goyal; James I. Fells; Donna H. Perygin; Wolfgang Siess; Abby L. Parrill; Gabor Tigyi; Yuko Fujiwara

  JOURNAL OF BIOLOGICAL CHEMISTRY 284 (25) 17304 - 17319 0021-9258 2009/06 [Refereed]
  
• Lysophosphatidic acid 2 receptor-mediated supramolecular complex formation regulates its antiapoptotic effect.

  Shuyu E; Yun-Ju Lai; Ryoko Tsukahara; Chen-Shan Chen; Yuko Fujiwara; Junming Yue; Jei-Hwa Yu; Huazhang Guo; Akio Kihara; Gábor Tigyi; Fang-Tsyr Lin

  The Journal of biological chemistry 284 (21) 14558 - 71 0021-9258 2009/05 [Refereed]
  
• Cyclic phosphatidic acid - a unique bioactive phospholipid.

  Fujiwara Y

  Biochimica et biophysica acta 1781 (9) 519 - 524 0006-3002 2008/09 [Refereed]
  
• Identification of non-lipid LPA(3) antagonists by virtual screening

  James I. Fells; Ryoko Tsukahara; Yuko Fujiwara; Jianxiong Liu; Donna H. Perygin; Daniel A. Osborne; Gabor Tigyi; Abby L. Parrill

  BIOORGANIC & MEDICINAL CHEMISTRY 16 (11) 6207 - 6217 0968-0896 2008/06 [Refereed]
  
• Subtype-specific residues involved in ligand activation of the endothelial differentiation gene family lysophosphatidic acid receptors

  William J. Valentine; James I. Fells; Donna H. Perygin; Sana Mujahid; Kazuaki Yokoyama; Yuko Fujiwara; Ryoko Tsukahara; James R. Van Brocklyn; Abby L. Parrill; Gabor Tigyi

  JOURNAL OF BIOLOGICAL CHEMISTRY 283 (18) 12175 - 12187 0021-9258 2008/05 [Refereed]
  
• Lysophospholipid signaling: Beyond the EDGs

  William J. Valentine; Yuko Fujiwara; Ryoko Tsukahara; Gabor Tigyi

  BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1780 (3) 597 - 605 0304-4165 2008/03 [Refereed]
  
• Lysophospholipid signaling: beyond the EDGs.

  Valentine WJ; Fujiwara Y; Tsukahara R; Tigyi G

  Biochimica et biophysica acta 1780 (3) 597 - 605 0006-3002 2008/03 [Refereed]
  
• Synthesis, pharmacology, and cell biology of sn-2-aminooxy analogues of lysophosphatidic acid

  Joanna Gajewiak; Ryoko Tsukahara; Yuko Fujiwara; Gabor Tigyi; Glenn D. Prestwich

  ORGANIC LETTERS 10 (6) 1111 - 1114 1523-7060 2008/03 [Refereed]
  
• Alkoxymethylenephosphonate analogues of (Lyso)phosphatidic acid stimulate signaling networks coupled to the LPA(2) receptor

  Joanna Gajewiak; Ryoko Tsukahara; Tamotsu Tsukahara; Yuko Fujiwara; Shuanxing Yu; Wing Lu; Mandi Murph; Gordon B. Mills; Gabor Tigyi; Gleen D. Prestwich

  CHEMMEDCHEM 2 (12) 1789 - 1798 1860-7179 2007/12 [Refereed]
  
• alpha-substituted phosphonate analogues of lysophosphatidic acid (LPA) selectively inhibit production and action of LPA

  Guowei Jiang; Yong Xu; Yuko Fujiwara; Tamotsu Tsukahara; Ryoko Tsukahara; Joanna Gajewiak; Gabor Tigyi; Glenn D. Prestwich

  CHEMMEDCHEM 2 (5) 679 - 690 1860-7179 2007/05 [Refereed]
  
• Inhibition of transcellular tumor cell migration and metastasis by novel carba-derivatives of cyclic phosphatidic acid

  Ayako Uchiyama; Mutsuko Mukai; Yuko Fujiwara; Susumu Kobayashi; Nobuyuki Kawai; Hiromu Murofushi; Masahiro Inoue; Shigenori Enoki; Yuichiro Tanaka; Tamotsu Niki; Tetsuyuki Kobayashi; Gabor Tigyi; Kimiko Murakami-Murofushi

  BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS 1771 (1) 103 - 112 1388-1981 2007/01 [Refereed]
  
• Identification of the hydrophobic ligand binding pocket of the S1P(1) receptor

  Yuko Fujiwara; Daniel A. Osborne; Michelle D. Walker; De-an Wang; Debra A. Bautista; Karoly Liliom; James R. Van Brocklyn; Abby L. Parrill; Gabor Tigyi

  JOURNAL OF BIOLOGICAL CHEMISTRY 282 (4) 2374 - 2385 0021-9258 2007/01 [Refereed]
  
• Inhibition of transcellular tumor cell migration and metastasis by novel carba-derivatives of cyclic phosphatidic acid.

  Uchiyama A; Mukai M; Fujiwara Y; Kobayashi S; Kawai N; Murofushi H; Inoue M; Enoki S; Tanaka Y; Niki T; Kobayashi T; Tigyi G; Murakami-Murofushi K

  Biochimica et biophysica acta 1771 (1) 103 - 112 0006-3002 2007/01 [Refereed]
  
• Carba analogs of cyclic phosphatidic acid are selective inhibitors of autotaxin and cancer cell invasion and metastasis

  Daniel L. Baker; Yuko Fujiwara; Kathryn R. Pigg; Ryoko Tsukahara; Susumu Kobayashi; Hiromu Murofushi; Ayako Uchiyama; Kimiko Murakami-Murofushi; Eunjin Koh; Russell W. Bandle; Hoe-Sup Byun; Robert Bittman; Dominic Fan; Mandi Murph; Gordon B. Mills; Gabor Tigyi

  JOURNAL OF BIOLOGICAL CHEMISTRY 281 (32) 22786 - 22793 0021-9258 2006/08 [Refereed]
  
• Phosphonothioate and fluoromethylene phosphonate analogues of cyclic phosphatidic acid: Novel antagonists of lysophosphatidic acid receptors

  Yong Xu; Guowei Jiang; Ryoko Tsukahara; Yuko Fujiwara; Gabor Tigyi; Glenn D. Prestwich

  JOURNAL OF MEDICINAL CHEMISTRY 49 (17) 5309 - 5315 0022-2623 2006/08 [Refereed]
  
• Serine phosphorylation differentially affects RhoA binding to effectors: Implications to NGF-induced neurite outgrowth

  N Nusser; E Gosmanova; N Makarova; Y Fujiwara; L Yang; FK Guo; YN Luo; Y Zheng; G Tigyi

  CELLULAR SIGNALLING 18 (5) 704 - 714 0898-6568 2006/05 [Refereed]
  
• Cell migration activated by platelet-derived growth factor receptor is blocked by an inverse agonist of the sphingosine 1-phosphate receptor-1.

  Waters CM; Long J; Gorshkova I; Fujiwara Y; Connell M; Belmonte KE; Tigyi G; Natarajan V; Pyne S; Pyne NJ

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20 (3) 509 - 511 0892-6638 2006/03 [Refereed]
  
• Phosphorothioate analogues of alkyl lysophosphaticlic acid as LPA(3) receptor-selective agonists

  Lian Qian; Yong Xu; Ted Simper; Guowei Jiang; Junken Aoki; Makiko Umezu-Goto; Hiroyuki Arai; Shuangxing Yu; Gordon B. Mills; Ryoko Tsukahara; Natalia Makarova; Yuko Fujiwara; Gabor Tigyi; Glenn D. Prestwich

  CHEMMEDCHEM 1 (3) 376 - 383 1860-7179 2006/03 [Refereed]
  
• Synthesis and pharmacological evaluation of second-generation phosphatidic acid derivatives as lysophosphatidic acid receptor ligands

  GG Durgam; R Tsukahara; N Makarova; MD Walker; Y Fujiwara; KR Pigg; DL Baker; VM Sardar; AL Parrill; G Tigyi; DD Miller

  BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 16 (3) 633 - 640 0960-894X 2006/02 [Refereed]
  
• Identification of Darmstoff analogs as selective agonists and antagonists of lysophosphatidic acid receptors

  Gududuru, V; K Zeng; R Tsukahara; N Makarova; Y Fujiwara; KR Pigg; DL Baker; G Tigyi; DD Miller

  BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 16 (2) 451 - 456 0960-894X 2006/01 [Refereed]
  
• Identification of residues responsible for ligand recognition and regioisomeric selectivity of lysophosphatidic acid receptors expressed in mammalian cells

  Y Fujiwara; Sardar, V; A Tokumura; D Baker; K Murakami-Murofushi; A Parrill; G Tigyi

  JOURNAL OF BIOLOGICAL CHEMISTRY 280 (41) 35038 - 35050 0021-9258 2005/10 [Refereed]
  
• Lysophosphatidic acid inhibits cholera toxin-induced secretory diarrhea through CFTR-dependent protein interactions

  CY Li; KS Dandridge; A Di; KL Marrs; EL Harris; K Roy; JS Jackson; NV Makarova; Y Fujiwara; PL Farrar; DJ Nelson; GJ Tigyi; AP Naren

  JOURNAL OF EXPERIMENTAL MEDICINE 202 (7) 975 - 986 0022-1007 2005/10 [Refereed]
  
• Sphingosine 1-phosphate analogue recognition and selectivity at S1P(4) within the endothelial differentiation gene family of receptors

  Y Inagaki; TT Pham; Y Fujiwara; T Kohno; DA Osborne; Y Igarashi; G Tigyi; AL Parrill

  BIOCHEMICAL JOURNAL 389 (Pt 1) 187 - 195 0264-6021 2005/07 [Refereed]
  
• Cyclic phosphatidic acid elicits neurotrophin-like actions in embryonic hippocampal neurons

  Y Fujiwara; A Sebok; S Meakin; T Kobayashi; K Murakami-Murofushi; G Tigyi

  JOURNAL OF NEUROCHEMISTRY 87 (5) 1272 - 1283 0022-3042 2003/12 [Refereed]
  
• Biological functions of a novel lipid mediator, cyclic phosphatidic acid.

  Murakami-Murofushi K; Uchiyama A; Fujiwara Y; Kobayashi T; Kobayashi S; Mukai M; Murofushi H; Tigyi G

  Biochimica et biophysica acta 1582 (1-3) 1 - 7 0006-3002 2002/05 [Refereed]
  

MISC

• 大腸がん組織中に蓄積する極長鎖脂肪酸の解析

  濱 弘太郎; 藤原 優子; 端山 軍; 小澤 毅士; 金子 建介; 橋口 陽二郎; 横山 和明  日本生化学会大会プログラム・講演要旨集  94回-  108  -108  2021/11
• Abcd1ノックアウトマウスの脳のスフィンゴミエリン分子種の解析

  濱 弘太郎; 藤原 優子; 守田 雅志; 今中 常雄; 下澤 伸行; 横山 和明  日本生化学会大会プログラム・講演要旨集  89回-  [1P  -062]  2016/09
• Abcd1ノックアウトマウスの脳のスフィンゴミエリン分子種の解析

  濱 弘太郎; 藤原 優子; 守田 雅志; 今中 常雄; 下澤 伸行; 横山 和明  JSBMS Letters  41-  (Suppl.)  70  -70  2016/08
• Abcd1ノックアウトマウスの脳のスフィンゴミエリン分子種の解析

  濱 弘太郎; 藤原 優子; 守田 雅志; 今中 常雄; 下澤 伸行; 横山 和明  脂質生化学研究  58-  97  -98  2016/05
• ESI-LC/MSを用いたAbcd1ノックアウトマウスの脳のリン脂質解析

  濱 弘太郎; 藤原 優子; 守田 雅志; 今中 常雄; 下澤 伸行; 横山 和明  日本先天代謝異常学会雑誌  31-  189  -189  2015/10
• abcd1ノックアウトマウスの脳のリン脂質解析

  濱 弘太郎; 藤原 優子; 守田 雅志; 今中 常雄; 下澤 伸行; 横山 和明  JSBMS Letters  40-  (Suppl.)  84  -84  2015/08
• 多段階MRMモードを用いたAbcd1ノックアウトマウスの脳の脂質解析

  濱 弘太郎; 藤原 優子; 松本 隼; 守田 雅志; 今中 常雄; 下澤 伸行; 横山 和明  脂質生化学研究  57-  144  -145  2015/05
• LC/MSによるリン脂質分子種別の網羅的解析方法の樹立(ALDにおける病型診断バイオマーカーの発見を目指して)

  濱 弘太郎; 藤原 優子; 今中 常雄; 下澤 伸行  日本先天代謝異常学会雑誌  30-  186  -186  2014/10
• 副腎白質ジストロフィー患者血漿中リン脂質の網羅的解析

  濱 弘太郎; 藤原 優子; 今中 常雄; 下澤 伸行; 横山 和明  日本生化学会大会プログラム・講演要旨集  87回-  [2P  -045]  2014/10
• BIOL 50-Optimization of the LPA5 receptor model for therapeutic lead discovery

  Jesica R. Williams; Yuko Fujiwara; Gabor Tigyi; Soujanya Balasankoula; Abby L. Parrill  ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY  236-  2008/08
• Modeling and mutagenesis of the mouse S1P4 receptor.

  TC Pham; Y Inagaki; Y Igarashi; Y Fujiwara; G Tigyi; AL Parrill  ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY  227-  U910  -U910  2004/03

Research Grants & Projects

• スフィンゴ糖脂質分析法の確立がもたらす副腎白質ジストロフィーの病態解明

  日本学術振興会：科学研究費助成事業 基盤研究(C)

  Date (from‐to) : 2022/04 -2026/03 

  Author : 藤原 優子
• 質量分析を用いたスフィンゴ糖脂質定量解析法の構築

  私学事業団：2019年度 学術研究振興資金 女性研究者奨励金

  Date (from‐to) : 2019/04 -2020/03 

  Author : 藤原優子
• Establishment of glycosphingolipid analysis in biological samples and application in clinical diagnosis of inherited metabolic disorders

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 2015/04 -2018/03 

  Author : Fujiwara Yuko
• 基盤研究C

  日本学術振興会：科学研究費助成事業

  Date (from‐to) : 2015/04 -2018/03 

  Author : 藤原優子
• Beginning Grant-in-Aid

  American Heart Association：

  Date (from‐to) : 2009/07 -2011/06 

  Author : Yuko Fujiwara
• Postdoctoral Fellowship

  American Heart Association：

  Date (from‐to) : 2006/07 -2008/06 

  Author : Yuko Fujiwara