松村　暢子 (マツムラ　ノブコ)

研究者情報

所属

• 基礎医学 講師
• 薬理学講座 講師

学位

• 博士（理学）

研究キーワード

• 神経保護機構   プリン体   グルタチオン   骨髄間葉系幹細胞   神経変性疾患   microRNA   

研究分野

• ライフサイエンス / 薬理学
• ライフサイエンス / 神経科学一般

経歴

• 2023年04月 - 現在  帝京大学医学部薬理学講座講師
• 2023年 - 現在  人間総合科学大学保健医療学部非常勤講師
• 2011年 - 現在  帝京高等看護学院非常勤講師
• 2007年04月 - 2023年03月  帝京大学医学部薬理学講座助教
• 1999年04月 - 2007年03月  帝京大学医学部 薬理学講座 助手

所属学協会

• 日本生化学会   日本薬理学会   

研究活動情報

論文

• Increased Brain Glutathione Levels by Intranasal Insulin Administration

  Taisuke Kawashima; Wattanaporn Bhadhprasit; Nobuko Matsumura; Chisato Kinoshita; Koji Aoyama

  Current Issues in Molecular Biology 47 4 284 - 284 2025年04月 [査読有り]
  
• Erythroid Differentiation Regulator 1 as a Regulator of Neuronal GSH Synthesis

  Wattanaporn Bhadhprasit; Chisato Kinoshita; Nobuko Matsumura; Koji Aoyama

  Antioxidants 13 7 771 - 771 2024年06月 [査読有り]
  
• Glutathione-Mediated Neuroprotective Effect of Purine Derivatives.

  Nobuko Matsumura; Koji Aoyama

  International journal of molecular sciences 24 17 2023年08月 [査読有り]
  
• A purine derivative, paraxanthine, promotes cysteine uptake for glutathione synthesis.

  Nobuko Matsumura; Chisato Kinoshita; Wattanaporn Bhadhprasit; Toshio Nakaki; Koji Aoyama

  Journal of pharmacological sciences 151 1 37 - 45 2023年01月 [査読有り]
  
• Inhibition of miR-96-5p in the mouse brain increases glutathione levels by altering NOVA1 expression.

  Chisato Kinoshita; Kazue Kikuchi-Utsumi; Koji Aoyama; Ryo Suzuki; Yayoi Okamoto; Nobuko Matsumura; Daiki Omata; Kazuo Maruyama; Toshio Nakaki

  Communications biology 4 1 182 - 182 2021年02月 [査読有り]
  
• Mechanism of glutathione production in neurons

  Nobuko Matsumura; Chisato Kinoshita; Koji Aoyama

  Folia Pharmacologica Japonica 156 1 26 - 30 2021年 [査読有り]
  
• GTRAP3-18 regulates food intake and body weight by interacting with pro-opiomelanocortin.

  Aoyama K; Bhadhprasit W; Watabe M; Wang F; Matsumura N; Nakaki T

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 32 1 330 - 341 2017年09月 [査読有り]
  
• Isobolographic analysis of the mechanisms of action of anticonvulsants from a combination effect

  Nobuko Matsumura; Toshio Nakaki

  EUROPEAN JOURNAL OF PHARMACOLOGY 741 237 - 246 2014年10月 [査読有り]
  
• Rhythmic oscillations of the microRNA miR-96-5p play a neuroprotective role by indirectly regulating glutathione levels

  Chisato Kinoshita; Koji Aoyama; Nobuko Matsumura; Kazue Kikuchi-Utsumi; Masahiko Watabe; Toshio Nakaki

  NATURE COMMUNICATIONS 5 3823  2014年05月 [査読有り]
  
• Involvement of the α(1D)-adrenergic receptor in methamphetamine-induced hyperthermia and neurotoxicity in rats.

  Kikuchi-Utsumi K; Ishizaka M; Matsumura N; Watabe M; Aoyama K; Sasakawa N; Nakaki T

  Neurotoxicity research 24 130 - 138 2 2013年08月 [査読有り]
  
• Anticonvulsant action of indazole.

  Nobuko Matsumura; Kazue Kikuchi-Utsumi; Kentaro Sakamaki; Masahiko Watabe; Koji Aoyama; Toshio Nakaki

  Epilepsy research 104 3 203 - 16 2013年05月 [査読有り]
  
• Alpha_1A-adrenergic control of piloerection and palpebral fissure width in rats.

  Kikuchi-Utsumi K; Ishizaka M; Matsumura N; Nakaki T

  Autonomic neuroscience : basic & clinical 179 1-2 148 - 150 2013年05月 [査読有り]
  
• Increased neuronal glutathione and neuroprotection in GTRAP3-18-deficient mice.

  Aoyama K; Wang F; Matsumura N; Kiyonari H; Shioi G; Tanaka K; Kinoshita C; Kikuchi-Utsumi K; Watabe M; Nakaki T

  Neurobiology of disease 45 3 973 - 982 2012年03月 [査読有り]
  
• Caffeine and uric acid mediate glutathione synthesis for neuroprotection.

  Aoyama K; Matsumura N; Watabe M; Wang F; Kikuchi-Utsumi K; Nakaki T

  Neuroscience 181 5 206 - 215 2011年05月 [査読有り]
  
• Activities of 7-nitroindazole and 1-(2-(trifluoromethylphenyl)-imidazole independent of neuronal nitric-oxide synthase inhibition.

  Matsumura N; Kikuchi-Utsumi K; Nakaki T

  The Journal of pharmacology and experimental therapeutics 325 357 - 362 2 2008年05月 [査読有り]
  
• Oxidative stress on EAAC1 is involved in MPTP-induced glutathione depletion and motor dysfunction.

  Aoyama K; Matsumura N; Watabe M; Nakaki T

  The European journal of neuroscience 27 20 - 30 1 2008年01月 [査読有り]
  
• Nigrostriatal pathway laterality in unlesioned old female rats

  Mishima A; Fujii T; Matsumura N; Maruyama D; Hishikawa K; Nakaki T

  Neuroscience Research Communications 30 2 63 - 70 2002年04月 [査読有り]
  
• Effects of nicotine on motor activity, passive avoidance and plus-maze behavior in aged NMRI and C57BL mice

  Akira Mishima; Tomoko Fujii; Nobuko Matsumura; Daisuke Maruyama; Keiichi Hishikawa; Toshio Nakaki

  Neuroscience Research Communications 30 2 91 - 101 2002年01月 [査読有り]
  
• Glufosinate ammonium induces convulsion through N-methyl-D-aspartate receptors in mice

  Matsumura N; Takeuchi C; Hishikawa K; Fujii T; Nakaki T

  Neuroscience Letters 304 1-2 123 - 125 2001年05月 [査読有り]
  
• Involvement of cytosolic NAD+ glycohydrolase in cyclic ADP-ribose metabolism.

  Matsumura N; Tanuma S

  Biochem Biophys Res Commun 253 2 246 - 252 1998年12月 [査読有り]
  
• Role of (ADP-ribose)n catabolism in DNA repair.

  Maruta H; Matsumura N; Tanuma S

  Biochem Biophys Res Commun 236 2 265 - 269 1997年07月 [査読有り]
  

講演・口頭発表等

• 学修支援システム(Prime Learning)を用いた反転授業の学修効果

  青山晃治; 松村暢子

  医学教育 2024年

MISC

• Involvement of brain arginine increase in glufosinate ammonium-induced delayed convulsion

  N Matsumura; M Okanaga; T Nakaki JOURNAL OF PHARMACOLOGICAL SCIENCES 97 260P -260P 2005年
• Mechanisms underlying glufosinate-ammonium-induced delayed convulsion

  N Matsumura; M Ishizaka; T Nakaki JOURNAL OF PHARMACOLOGICAL SCIENCES 94 166P -166P 2004年
• Decrease in brain glutamate content during glufosinate ammonium-induced convulsion in mouse.

  N Matsumura; M Ishizaka; K Hishikawa; T Fujii; T Nakaki JOURNAL OF PHARMACOLOGICAL SCIENCES 91 204P -204P 2003年