Murata Takuya

Researcher Information

Affiliation

Faculty of Pharmaceutical Sciences Senior Assistant Professor
Graduate School of Pharmaceutical Sciences Senior Assistant Professor

URL

https://jglobal.jst.go.jp/detail?JGLOBAL_ID=201901008492009047

J-Global ID

• 201901008492009047

Research Areas

• Life sciences / Molecular biology

Academic & Professional Experience

• 2022/05 - Today  Teikyo UniversityFaculty of Pharma-Science
• 2011/04 - 2022/04  Teikyo UniversityFaculty of Pharma-Science

Education

• 2002/04 - 2006/03  The University of Tokyo  Faculty of Science  Department of Chemistry

Research Activity Information

Published Papers

• Impacts of D-aspartate on the Aggregation Kinetics and Structural Polymorphism of Amyloid β Peptide 1–42

  Li-Ching Hsiao; Chih-Hsuan Lee; Karine Mazmanian; Masaya Yoshida; Genta Ito; Takuya Murata; Naoko Utsunomiya-Tate; Takeharu Haino; Shih-ichi Tate; Shang-Te Danny Hsu

  Journal of Molecular Biology Elsevier BV 437 (12) 169092 - 169092 0022-2836 2025/06
• Site-specific amino acid D-isomerization of Tau R2 and R3 peptides changes the fibril morphology, resulting in attenuation of Tau aggregation inhibitor potency.

  Takuya Murata; Genta Ito; Naoko Utsunomiya-Tate

  Biochemical and biophysical research communications 654 18 - 25 2023/04 [Refereed]
  
• A tailored tetravalent peptide displays dual functions to inhibit amyloid β production and aggregation

  Waka Sato; Miho Watanabe-Takahashi; Takuya Murata; Naoko Utsunomiya-Tate; Jun Motoyama; Masataka Anzai; Seiko Ishihara; Nanako Nishioka; Hina Uchiyama; Juri Togashi; Saeka Nishihara; Kiyoshi Kawasaki; Takashi Saito; Takaomi C. Saido; Satoru Funamoto; Kiyotaka Nishikawa

  Communications Biology Springer Science and Business Media LLC 6 (1) 2023/04 [Refereed]
  
• Physicochemical characterization of the G51D mutation of α-synuclein that is responsible for its severe cytotoxicity.

  Takuya Murata; Naoya Tochio; Naoko Utsunomiya-Tate

  Neuroscience letters 760 136077 - 136077 2021/08 [Refereed]
  
• The dynamic structure of Rab35 is stabilized in the presence of GTP under physiological conditions.

  Takuya Murata; Yuka Unno; Mitsunori Fukuda; Naoko Utsunomiya-Tate

  Biochemistry and biophysics reports 23 100776 - 100776 2020/09 [Refereed]
  
• Effect of site-specific amino acid D-isomerization on β-sheet transition and fibril formation profiles of Tau microtubule-binding repeat peptides.

  Tochio N; Murata T; Utsunomiya-Tate N

  Biochemical and biophysical research communications 508 (1) 184 - 190 0006-291X 2019/01 [Refereed]
  
• Correction: "Corepressive action of CBP on androgen receptor transactivation in pericentric heterochromatin in a Drosophila experimental model system" [Molecular and Cellular Biology, 29, 4, (2009), (1017-1034)] doi 10.1128/MCB.02123-07

  Yue Zhao; Ken-Ichi Takeyama; Shun Sawatsubashi; Saya Ito; Eriko Suzuki; Kaoru Yamagata; Masahiko Tanabe; Shuhei Kimura; Sally Fujiyama; Takashi Ueda; Takuya Murata; Hiroyuki Matsukawa; Yuko Shirode; Alexander P. Kouzmenko; Feng Li; Testuya Tabata; Shigeaki Kato

  Molecular and Cellular Biology American Society for Microbiology 37 (18) 1098-5549 2017/09 [Refereed]
  
• Corepressive Action of CBP on Androgen Receptor Transactivation in Pericentric Heterochromatin in a Drosophila Experimental Model System (vol 29, pg 1017, 2009)

  Yue Zhao; Ken-ichi Takeyama; Shun Sawatsubashi; Saya Ito; Eriko Suzuki; Kaoru Yamagata; Masahiko Tanabe; Shuhei Kimura; Sally Fujiyama; Takashi Ueda; Takuya Murata; Hiroyuki Matsukawa; Yuko Shirode; Alexander P. Kouzmenko; Feng Li; Testuya Tabata; Shigeaki Kato

  MOLECULAR AND CELLULAR BIOLOGY 37 (18) 0270-7306 2017/09 [Refereed]
  
• Epigenetic Silencing of Core Histone Genes by HERS in Drosophila

  Saya Ito; Sally Fujiyama-Nakamura; Shuhei Kimura; Jinseon Lim; Yuki Kamoshida; Yumi Shiozaki-Sato; Shun Sawatsubashi; Eriko Suzuki; Masahiko Tanabe; Takashi Ueda; Takuya Murata; Hiromi Kato; Fumiaki Ohtake; Ryoji Fujiki; Tsuneharu Miki; Alexander Kouzmenko; Ken-ichi Takeyama; Shigeaki Kato

  MOLECULAR CELL 45 (4) 494 - 504 1097-2765 2012/02 [Refereed]
  
• A histone chaperone, DEK, transcriptionally coactivates a nuclear receptor

  Shun Sawatsubashi; Takuya Murata; Jinseon Lim; Ryoji Fujiki; Saya Ito; Eriko Suzuki; Masahiko Tanabe; Yue Zhao; Shuhei Kimura; Sally Fujiyama; Takashi Ueda; Daiki Umetsu; Takashi Ito; Ken-ichi Takeyama; Shigeaki Kato

  GENES & DEVELOPMENT 24 (2) 159 - 170 0890-9369 2010/01 [Refereed]
  
• Maturation of MicroRNA Is Hormonally Regulated by a Nuclear Receptor (Retracted article. See vol. 54, pg. 536, 2014)

  Kaoru Yamagata; Sally Fujiyama; Saya Ito; Takashi Ueda; Takuya Murata; Masanori Naitou; Ken-ichi Takeyama; Yasuhiro Minami; Bert W. O'Malley; Shigeaki Kato

  MOLECULAR CELL 36 (2) 340 - 347 1097-2765 2009/10 [Refereed]
  
• BTB protein, dKLHL18/CG3571, serves as an adaptor subunit for a dCul3 ubiquitin ligase complex

  Sally Fujiyama-Nakamura; Saya Ito; Shun Sawatsubashi; Yoshio Yamauchi; Eriko Suzuki; Masahiko Tanabe; Shuhei Kimura; Takuya Murata; Toshiaki Isobe; Ken-ichi Takeyama; Shigeaki Kato

  GENES TO CELLS 14 (8) 965 - 973 1356-9597 2009/08 [Refereed]
  
• Aberrant E2F activation by polyglutamine expansion of androgen receptor in SBMA neurotoxicity

  Eriko Suzuki; Yue Zhao; Saya Ito; Shun Sawatsubashi; Takuya Murata; Takashi Furutani; Yuko Shirode; Kaoru Yamagata; Masahiko Tanabe; Shuhei Kimura; Takashi Ueda; Sally Fujiyama; Jinseon Lim; Hiroyuki Matsukawa; Alexander P. Kouzmenko; Toshiro Aigaki; Tetsuya Tabata; Ken-ichi Takeyama; Shigeaki Kato

  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 106 (10) 3818 - 3822 0027-8424 2009/03 [Refereed]
  
• Corepressive Action of CBP on Androgen Receptor Transactivation in Pericentric Heterochromatin in a Drosophila Experimental Model System

  Yue Zhao; Ken-ichi Takeyama; Shun Sawatsubashi; Saya Ito; Eriko Suzuki; Kaoru Yamagata; Masahiko Tanabe; Shuhei Kimura; Sally Fujiyama; Takashi Ueda; Takuya Murata; Hiroyuki Matsukawa; Yuko Shirode; Alexander P. Kouzmenko; Feng Li; Testuya Tabata; Shigeaki Kato

  MOLECULAR AND CELLULAR BIOLOGY 29 (4) 1017 - 1034 0270-7306 2009/02 [Refereed]
  
• RNA-binding protein hoip accelerates polyQ-induced neurodegeneration in Drosophila

  Takuya Murata; Eriko Suzuki; Saya Ito; Shun Sawatsubashi; Yue Zhao; Kaoru Yamagata; Masahiko Tanabe; Sally Fujiyama; Shuhei Kimura; Takashi Ueda; Hiroyuki Matsukawa; Alexander Kouzmenko; Takashi Furutani; Erina Kuranaga; Masayuki Miura; Ken-ichi Takeyama; Shigeaki Kato

  BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY 72 (9) 2255 - 2261 0916-8451 2008/09 [Refereed]
  
• Drosophila arginine methyltransferase 1 (DART1) is an ecdysone receptor co-repressor

  Shuhei Kimura; Shun Sawatsubashi; Saya Ito; Alexander Kouzmenko; Eriko Suzuki; Yue Zhao; Kaoru Yamagata; Masahiko Tanabe; Takashi Ueda; Sari Fujiyama; Takuya Murata; Hiroyuki Matsukawa; Ken-ichi Takeyama; Nobuo Yaegashi; Shigeaki Kato

  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 371 (4) 889 - 893 0006-291X 2008/07 [Refereed]
  

Awards & Honors

• 2009/03 日本農芸化学会 BBB論文賞
   

  受賞者: 村田拓哉

Research Grants & Projects

• Identification and functional analysis of the transcriptonal complex regulating haematopoiesis

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 2012/04 -2014/03 

  Author : MURATA Takuya