Aoki Naoya

Researcher Information

Affiliation

Faculty of Pharmaceutical Sciences Associate Professor
Graduate School of Pharmaceutical Sciences Associate Professor

URL

https://jglobal.jst.go.jp/detail?JGLOBAL_ID=201401090187919417

J-Global ID

• 201401090187919417

Research Interests

• Acetylcholine   GABA   学習臨界期   刻印付け   

Research Areas

• Life sciences / Pharmaceuticals - health and biochemistry

Academic & Professional Experience

• 2019/04 - Today  Teikyo UniversityFaculty of Pharmaceutical sciencesassociate professor
• 2015/10 - 2019/03  Teikyo UniversityFaculty of Pharmaceutical scienceslecturer
• 2010/04 - 2015/09  Teikyo UniversityFaculty of Pharmaceutical sciences
• 2007/07 - 2010/03  RIKENBrain science institutepostdoctoral fellow
• 2006/04 - 2007/06  University of MinnesotaDepartment of Neurosciencepostdoctoral fellow

Association Memberships

• Society for Neuroscience   THE JAPAN NEUROSCIENCE SOCIETY   

Research Activity Information

Published Papers

• Molecular characterization of chicken DA systems reveals that the avian personality gene, DRD4, is expressed in the mitral cells of the olfactory bulb

  Toshiyuki Fujita; Naoya Aoki; Chihiro Mori; Koichi J. Homma; Shinji Yamaguchi

  Frontiers in Neuroanatomy Frontiers Media SA 19 2025/01
• Perihatch surge of thyroid hormone drives cognitive flexibility in newborn chicks

  Naoya Aoki; Chihiro Mori; Shouta Serizawa; Toshiyuki Fujita; Shinji Yamaguchi; Koichi J. Homma

  Science Advances American Association for the Advancement of Science (AAAS) 10 (41) 2024/10 [Refereed]
  
• SoxC and MmpReg promote blastema formation in whole-body regeneration of fragmenting potworms Enchytraeus japonensis

  Toshiyuki Fujita; Naoya Aoki; Chihiro Mori; Koichi J. Homma; Shinji Yamaguchi

  Nature Communications Springer Science and Business Media LLC 15 (1) 2024/08
• Molecular biology of serotonergic systems in avian brains

  Toshiyuki Fujita; Naoya Aoki; Chihiro Mori; Koichi J. Homma; Shinji Yamaguchi

  Frontiers in Molecular Neuroscience Frontiers Media SA 16 2023/07
• Temporal hampering of thyroid hormone synthesis just before hatching impeded the filial imprinting in domestic chicks.

  Shouta Serizawa; Naoya Aoki; Chihiro Mori; Toshiyuki Fujita; Shinji Yamaguchi; Toshiya Matsushima; Koichi J Homma

  Frontiers in physiology 14 1084816 - 1084816 2023 [Refereed]
  
• Dopaminergic nuclei in the chick midbrain express serotonin receptor subfamily genes

  Toshiyuki Fujita; Naoya Aoki; Chihiro Mori; Shouta Serizawa; Fumiko Kihara-Negishi; Koichi J. Homma; Shinji Yamaguchi

  Frontiers in Physiology Frontiers Media SA 13 2022/11
• Subtype-selective contribution of muscarinic acetylcholine receptors for filial imprinting in newly-hatched domestic chicks.

  Naoya Aoki; Chihiro Mori; Toshiyuki Fujita; Shouta Serizawa; Shinji Yamaguchi; Toshiya Matsushima; Koichi J Homma

  Behavioural brain research 424 113789 - 113789 2022/04 [Refereed]
  
• Imprintability of Newly Hatched Domestic Chicks on an Artificial Object: A Novel High Time-Resolution Apparatus Based on a Running Disc.

  Naoya Aoki; Chihiro Mori; Toshiyuki Fujita; Shouta Serizawa; Shinji Yamaguchi; Toshiya Matsushima; Koichi J Homma

  Frontiers in physiology 13 822638 - 822638 2022/03 [Refereed]
  
• Gene expression profiles of the muscarinic acetylcholine receptors in brain regions relating to filial imprinting of newly-hatched domestic chicks.

  Chihiro Mori; Naoya Aoki; Toshiyuki Fujita; Shinji Yamaguchi; Toshiya Matsushima; Koichi J Homma

  Behavioural brain research 420 113708 - 113708 2022/02 [Refereed]
  
• Chick Hippocampal Formation Displays Subdivision- and Layer-Selective Expression Patterns of Serotonin Receptor Subfamily Genes.

  Toshiyuki Fujita; Naoya Aoki; Chihiro Mori; Eiko Fujita; Toshiya Matsushima; Koichi J Homma; Shinji Yamaguchi

  Frontiers in physiology 13 882633 - 882633 2022 [Refereed]
  
• Suppressive Modulation of the Chick Forebrain Network for Imprinting by Thyroid Hormone: An in Vitro Study.

  Yuriko Saheki; Naoya Aoki; Koichi J Homma; Toshiya Matsushima

  Frontiers in physiology 13 881947 - 881947 2022 [Refereed]
  
• Serotonergic Neurons in the Chick Brainstem Express Various Serotonin Receptor Subfamily Genes.

  Toshiyuki Fujita; Naoya Aoki; Chihiro Mori; Eiko Fujita; Toshiya Matsushima; Koichi J Homma; Shinji Yamaguchi

  Frontiers in physiology 12 815997 - 815997 2021 [Refereed]
  
• The dorsal arcopallium of chicks displays the expression of orthologs of mammalian fear related serotonin receptor subfamily genes.

  Toshiyuki Fujita; Naoya Aoki; Chihiro Mori; Eiko Fujita; Toshiya Matsushima; Koichi J Homma; Shinji Yamaguchi

  Scientific reports 10 (1) 21183 - 21183 2020/12 [Refereed]
  
• Blockade of muscarinic acetylcholine receptor by scopolamine impairs the memory formation of filial imprinting in domestic chicks (Gallus Gallus domesticus).

  Naoya Aoki; Toshiyuki Fujita; Chihiro Mori; Eiko Fujita; Shinji Yamaguchi; Toshiya Matsushima; Koichi J Homma

  Behavioural brain research 379 112291 - 112291 0166-4328 2020/02 [Refereed]
  
• The chick pallium displays divergent expression patterns of chick orthologues of mammalian neocortical deep layer-specific genes

  Fujita T; Aoki N; Fujita E; Matsushima T; Homma KJ; Yamaguchi S

  Scientific Reports 9 (1) 20400 - 20400 2019 [Refereed]
  
• GABA-A and GABA-B Receptors in Filial Imprinting Linked With Opening and Closing of the Sensitive Period in Domestic Chicks (Gallus gallus domesticus).

  Aoki N; Yamaguchi S; Fujita T; Mori C; Fujita E; Matsushima T; Homma KJ

  Frontiers in physiology Frontiers Media SA 9 1837  2018/12 [Refereed]
  
• Thyroid Hormone Sensitizes the Imprinting-Associated Induction of Biological Motion Preference in Domestic Chicks

  Miura M; Aoki N; Yamaguchi S; Homma KJ; Matsushima T

  Frontiers in Physiology Frontiers Media SA 9 1740  2018/12 [Refereed]
  
• Gene expression of Dio2 (thyroid hormone converting enzyme) in telencephalon is linked with predisposed biological motion preference in domestic chicks.

  Takemura Y; Yamaguchi S; Aoki N; Miura M; Homma KJ; Matsushima T

  Behavioural brain research Elsevier BV 349 25 - 30 0166-4328 2018/09 [Refereed]
  
• Wnt-2b in the intermediate hyperpallium apicale of the telencephalon is critical for the thyroid hormone-mediated opening of the sensitive period for filial imprinting in domestic chicks (Gallus gallus domesticus)

  Shinji Yamaguchi; Naoya Aoki; Toshiya Matsushima; Koichi J. Homma

  Hormones and Behavior Academic Press Inc. 102 120 - 128 1095-6867 2018/06 [Refereed]
  
• Sex Differences in Brain Thyroid Hormone Levels during Early Post-Hatching Development in Zebra Finch (Taeniopygia guttata)

  Shinji Yamaguchi; Shin Hayase; Naoya Aoki; Akihiko Takehara; Jun Ishigohoka; Toshiya Matsushima; Kazuhiro Wada; Koichi J. Homma

  PLOS ONE PUBLIC LIBRARY SCIENCE 12 (1) e0169643  1932-6203 2017/01 [Refereed]
  
• Involvement of nucleotide diphosphate kinase 2 in the reopening of the sensitive period of filial imprinting of domestic chicks (Gallus gallus domesticus)

  Shinji Yamaguchi; Naoya Aoki; Akihiko Takehara; Masaru Mori; Akio Kanai; Toshiya Matsushima; Koichi J. Homma

  NEUROSCIENCE LETTERS ELSEVIER IRELAND LTD 612 32 - 37 0304-3940 2016/01 [Refereed]
  
• CRITICAL ROLE OF THE NEURAL PATHWAY FROM THE INTERMEDIATE MEDIAL MESOPALLIUM TO THE INTERMEDIATE HYPERPALLIUM APICALE IN FILIAL IMPRINTING OF DOMESTIC CHICKS (GALLUS GALLUS DOMESTICUS)

  N. Aoki; S. Yamaguchi; T. Kitajima; A. Takehara; S. Katagiri-Nakagawa; R. Matsui; D. Watanabe; T. Matsushima; K. J. Homma

  NEUROSCIENCE PERGAMON-ELSEVIER SCIENCE LTD 308 115 - 124 0306-4522 2015/11 [Refereed]
  
• Potential Role of Voltage-Sensing Phosphatases in Regulation of Cell Structure Through the Production of PI(3,4)P-2

  Shinji Yamaguchi; Tatsuki Kurokawa; Ikuko Taira; Naoya Aoki; Souhei Sakata; Yasushi Okamura; Koichi J. Homma

  JOURNAL OF CELLULAR PHYSIOLOGY WILEY-BLACKWELL 229 (4) 422 - 433 0021-9541 2014/04 [Refereed]
  
• Expression of the voltage-sensing phosphatase gene in the chick embryonic tissues and in the adult cerebellum

  Shinji Yamaguchi; Naoya Aoki; Takaaki Kitajima; Yasushi Okamura; Koichi J Homma

  Communicative and Integrative Biology Landes Bioscience 7 (5) 1942-0889 2014 [Refereed]
  
• [A primer for learning: thyroid hormone is a determining factor to start the sensitive period of filial imprinting of domestic chicks].

  Homma KJ; Yamaguchi S; Aoki N

  Seikagaku. The Journal of Japanese Biochemical Society 5 85 315 - 327 0037-1017 2013/05 [Refereed]
  
• Insect Homologs of Papain

  Koichi J. Homma; Shinji Yamaguchi; Naoya Aoki

  Handbook of Proteolytic Enzymes Elsevier Ltd 2 1963 - 1968 2013 [Refereed]
  
• Thyroid hormone determines the start of the sensitive period of imprinting and primes later learning

  Shinji Yamaguchi; Naoya Aoki; Takaaki Kitajima; Eiji Iikubo; Sachiko Katagiri; Toshiya Matsushima; Koichi J. Homma

  NATURE COMMUNICATIONS NATURE PUBLISHING GROUP 3 1081  2041-1723 2012/09 [Refereed]
  
• Unusual Features of Chick VSP and its Potential Role in Regulation of Cell Structure

  Yasushi Okamura; Tatsuki Kurokawa; Shinji Yamaguchi; Naoya Aoki; Ikuko Taira; Souhei Sakata; Koichi Homma

  BIOPHYSICAL JOURNAL CELL PRESS 102 (3) 37A - 37A 0006-3495 2012/01 [Refereed]
  
• Identification of single neurons in a forebrain network

  Nancy F. Day; Stephen J. Kerrigan; Naoya Aoki; Teresa A. Nick

  JOURNAL OF NEUROPHYSIOLOGY AMER PHYSIOLOGICAL SOC 106 (6) 3205 - 3215 0022-3077 2011/12 [Refereed]
  
• Activation of brain-derived neurotrophic factor/tropomyosin-related kinase B signaling accompanying filial imprinting in domestic chicks (Gallus gallus domesticus)

  Shinji Yamaguchi; Naoya Aoki; Daisuke Kobayashi; Takaaki Kitajima; Eiji Iikubo; Sachiko Katagiri; Toshiya Matsushima; Koichi J. Homma

  NEUROREPORT LIPPINCOTT WILLIAMS & WILKINS 22 (17) 929 - 934 0959-4965 2011/12 [Refereed]
  
• Molecular function of microtubule-associated protein 2 for filial imprinting in domestic chicks (Gallus gallus domesticus)

  Shinji Yamaguchi; Sachiko Katagiri; Naoya Aoki; Eiji Iikubo; Takaaki Kitajima; Toshiya Matsushima; Koichi J. Homma

  NEUROSCIENCE RESEARCH ELSEVIER IRELAND LTD 69 (1) 32 - 40 0168-0102 2011/01 [Refereed]
  
• Up-regulation of microtubule-associated protein 2 accompanying the filial imprinting of domestic chicks (Gallus gallus domesticus)

  Shinji Yamaguchi; Ikuko Fujii-Taira; Akio Murakami; Naoki Hirose; Naoya Aoki; Ei-Ichi Izawa; Yasuyuki Fujimoto; Tatsuya Takano; Toshiya Matsushima; Koichi J. Homma

  BRAIN RESEARCH BULLETIN PERGAMON-ELSEVIER SCIENCE LTD 76 (3) 282 - 288 0361-9230 2008/06 [Refereed]
  
• Developmental modulation of the temporal relationship between brain and behavior

  Shane R. Crandall; Naoya Aoki; Teresa A. Nick

  JOURNAL OF NEUROPHYSIOLOGY AMER PHYSIOLOGICAL SOC 97 (1) 806 - 816 0022-3077 2007/01 [Refereed]
  
• Localized lesions of arcopallium intermedium of the lateral forebrain caused a handling-cost aversion in the domestic chick performing a binary choice task

  Naoya Aoki; Andras Csillag; Toshiya Matsushima

  EUROPEAN JOURNAL OF NEUROSCIENCE WILEY-BLACKWELL 24 (8) 2314 - 2326 0953-816X 2006/10 [Refereed]
  
• Localized lesions of ventral striatum, but not arcopallium, enhanced impulsiveness in choices based on anticipated spatial proximity of food rewards in domestic chicks

  N Aoki; R Suzuki; EI Izawa; A Csillag; T Matsushima

  BEHAVIOURAL BRAIN RESEARCH ELSEVIER SCIENCE BV 168 (1) 1 - 12 0166-4328 2006/03 [Refereed]
  
• Neural correlates of the proximity and quantity of anticipated food rewards in the ventral striatum of domestic chicks

  EI Izawa; N Aoki; T Matsushima

  EUROPEAN JOURNAL OF NEUROSCIENCE BLACKWELL PUBLISHING 22 (6) 1502 - 1512 0953-816X 2005/09 [Refereed]
  
• Neural correlates of memorized associations and cued movements in archistriatum of the domestic chick

  N Aoki; EI Izawa; S Yanagihara; T Matsushima

  EUROPEAN JOURNAL OF NEUROSCIENCE BLACKWELL PUBLISHING LTD 17 (9) 1935 - 1946 0953-816X 2003/05 [Refereed]
  
• The mind through chick eyes: Memory, cognition and anticipation

  T Matsushima; EI Izawa; N Aoki; S Yanagihara

  ZOOLOGICAL SCIENCE ZOOLOGICAL SOC JAPAN 20 (4) 395 - 408 0289-0003 2003/04 [Refereed]
  
• Lesions of the ventro-medial basal ganglia impair the reinforcement but not the recall of memorized color discrimination in domestic chicks

  EI Izawa; G Zachar; N Aoki; K Koga; T Matsushima

  BEHAVIOURAL BRAIN RESEARCH ELSEVIER SCIENCE BV 136 (2) 405 - 414 0166-4328 2002/11 [Refereed]
  

MISC

• 甲状腺ホルモンによって賦与されるニワトリヒナの早期学習能力

  本間光一; 青木直哉; 山口真二; 藤田俊之; 藤田永子  Annual Meeting of Japanese Avian Endocrinology  43rd-  2019
• 甲状腺ホルモンは課題転換での柔軟性を向上させる

  青木直哉; 藤田俊之; 藤田永子; 山口真二; 本間光一  Annual Meeting of Japanese Avian Endocrinology  43rd-  2019
• A primer for learning : Thyroid hormone is a determining factor to start the sensitive period of filial imprinting of domestic chicks

  HOMMA Koichi J; YAMAGUCHI Shinji; AOKI Naoya  生化學  85-  (5)  315  -327  2013/05
• Characterizations of chick voltage-sensing phosphatase and its possible role in regulation of cell structure

  Yasushi Okamura; Shinji Yamaguchi; Ikuko Taira; Tatsuki Kurokawa; Naoya Aoki; Souhei Sakata; Kouichi Homma  NEUROSCIENCE RESEARCH  71-  E230  -E230  2011
• Impulsive choice in domestic chicks: context dependence and dissociation between delay and handling cost

  Toshiya Matsushima; Naoya Aoki; Andras Csillag  NEUROSCIENCE RESEARCH  55-  S94  -S94  2006
• FUNCTIONAL ROLE OF 'ANTICIPATION' IN BASAL GANGLION OF DOMESTIC CHICKS : SUPPRESSION OF IMPULSIVENESS(Physiology)(Proceedings of the Seventy-Third Annual Meeting of the Zoological Society of Japan) :

  Izawa Ei-Ichi; Aoki Naoya; Matsushima Toshiya  Zoological science  19-  (12)  1469  -1469  2002
• MEMORY RELATED NEURONAL ACTIVITIES IN THE LIMBIC SYSTEM OF DOMESTIC CHICKS(Physiology)(Proceedings of the Seventy-Third Annual Meeting of the Zoological Society of Japan) :

  Aoki Naoya; Izawa Ei-Ichi; Matsushima Toshiya  Zoological science  19-  (12)  1469  -1469  2002

Research Grants & Projects

• 鳥類刷り込みの臨界期及び記憶形成に関わる神経伝達物質の行動薬理学的・生理学的解析

  日本学術振興会：科学研究費助成事業

  Date (from‐to) : 2020/04 -2023/03 

  Author : 青木 直哉
• Neural circuits of memory consolidation in filial imprinting of domestic chicks

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 2016/04 -2018/03 

  Author : Aoki Naoya
• Thyroid hormone-mediated actin dynamics regulate the reopening of the sensitive period of filial imprinting in chicks

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 2015/04 -2018/03 

  Author : Yamaguchi Shinji; AOKI Naoya
• functional roles of Brain-derived neurotrophic factor for filial imprinting of domestic chicks

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 2012/04 -2014/03 

  Author : AOKI Naoya
• The roles of immediate early genes and the morphological changes of dendritic spines in the filial imprinting of precocial birds.

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 2011 -2013 

  Author : HOMMA Koichi; AOKI Naoya