田村　真由美 (タムラ　マユミ)

研究者情報

所属

• 薬学部 助教
• 大学院薬学研究科 助教

URL

https://jglobal.jst.go.jp/detail?JGLOBAL_ID=201801009421046390

J-Global ID

• 201801009421046390

研究分野

• ライフサイエンス / 薬系衛生、生物化学

経歴

• 2007年04月 - 2018年06月  城西大学

研究活動情報

論文

• Galectin-2 Agglutinates Helicobacter pylori via Lipopolysaccharide Containing H Type I Under Weakly Acidic Conditions.

  Takaharu Sasaki; Midori Oyama; Mao Kubota; Yasunori Isshiki; Tomoharu Takeuchi; Toru Tanaka; Takashi Tanikawa; Mayumi Tamura; Yoichiro Arata; Tomomi Hatanaka

  International journal of molecular sciences 25 16 2024年08月
• Reduced form of Galectin-1 Suppresses Osteoclastic Differentiation of Human Peripheral Blood Mononuclear Cells and Murine RAW264 Cells In Vitro.

  Tomoharu Takeuchi; Midori Oyama; Mayumi Tamura; Yoichiro Arata; Tomomi Hatanaka

  Biomolecules 14 1 2024年01月
• Quantitation of Mucin by Densitometry of an Alcian Blue-Stained Membrane.

  Mayumi Tamura; Yoichiro Arata

  Methods in molecular biology (Clifton, N.J.) 2763 119 - 124 2024年
• Analysis of the Interaction Between Mucin and Green Fluorescent Protein (GFP)-Tagged Galectin-2 Using a 96-Well Plate.

  Mayumi Tamura; Yoichiro Arata

  Methods in molecular biology (Clifton, N.J.) 2763 311 - 319 2024年
• Method for Preparing Recombinant Galectin-2 Protein without Escherichia coli-Specific Post-translational Modifications.

  Mayumi Tamura; Norihiko Fujii; Tomoharu Takeuchi; Masato Tsuyuguchi; Takashi Tanikawa; Saori Oka; Tomomi Hatanaka; Seishi Kishimoto; Ryuichi Kato; Yoichiro Arata

  Biological & pharmaceutical bulletin 46 12 1676 - 1682 2023年
• Osteoclast differentiation is suppressed by increased O-GlcNAcylation due to thiamet G treatment

  Tomoharu Takeuchi; Yasuhiro Horimoto; Midori Oyama; Sachie Nakatani; Kenji Kobata; Mayumi Tamura; Yoichiro Arata; Tomomi Hatanaka

  Biological and Pharmaceutical Bulletin 43 10 1501 - 1505 2020年10月
• Galectin-2 Has Bactericidal Effects against Helicobacter pylori in a β-galactoside-Dependent Manner.

  Takaharu Sasaki; Rei Saito; Midori Oyama; Tomoharu Takeuchi; Toru Tanaka; Hideshi Natsume; Mayumi Tamura; Yoichiro Arata; Tomomi Hatanaka

  International journal of molecular sciences 21 8 2020年04月 [査読有り]
  
• Potential Interaction between Galectin-2 and MUC5AC in Mouse Gastric Mucus.

  Mayumi Tamura; Toru Tanaka; Norihiko Fujii; Takashi Tanikawa; Saori Oka; Tomoharu Takeuchi; Tomomi Hatanaka; Seishi Kishimoto; Yoichiro Arata

  Biological & pharmaceutical bulletin 43 2 356 - 360 2020年 [査読有り]
  
• Expression, S-Nitrosylation, and Measurement of S-Nitrosylation Ratio of Recombinant Galectin-2.

  Mayumi Tamura; Yoichiro Arata

  Methods in molecular biology (Clifton, N.J.) 2132 55 - 63 2020年 [査読有り]
  
• Galectin-2 suppresses nematode development by binding to the invertebrate-specific galactoseβ1-4fucose glyco-epitope.

  Takeuchi T; Tamura M; Ishiwata K; Hamasaki M; Hamano S; Arata Y; Hatanaka T

  Glycobiology 29 6 504 - 512 2019年06月 [査読有り]
  
• ガレクチン-2はβ-ガラクトシド依存的にH.pyloriの増殖を抑制する

  佐々木 啓晴; 田中 享; 武内 智春; 大竹 一男; 小林 順; 八巻 努; 内田 昌希; 夏目 秀視; 田村 真由美; 荒田 洋一郎; 畑中 朋美

  日本薬学会年会要旨集 139年会 3 67 - 67 (公社)日本薬学会 2019年03月
• エステル化合物の代謝に寄与する加水分解酵素の皮膚中濃度

  小林 鈴; 鹿倉 愛里彩; 田村 真由美; 武内 智春; 井上 貴暁; 藤堂 浩明; 杉林 堅次; 青山 謙一; 太田 嘉英; 今川 孝太郎; 赤松 正; 木村 穣; 畑中 朋美

  日本薬学会年会要旨集 139年会 4 125 - 125 (公社)日本薬学会 2019年03月 [査読有り]
  
• Structural mechanisms for the S-nitrosylation-derived protection of mouse galectin-2 from oxidation-induced inactivation revealed by NMR.

  Sakakura M; Tamura M; Takeuchi T; Hatanaka T; Arata Y; Takahashi H

  The FEBS journal 285 6 1129 - 1145 2018年06月 [査読有り]
  
• Identification of Galectin-2-Mucin Interaction and Possible Formation of a High Molecular Weight Lattice

  Mayumi Tamura; Dai Sato; Moeko Nakajima; Masanori Saito; Takaharu Sasaki; Toru Tanaka; Tomomi Hatanaka; Tomoharu Takeuchi; Yoichiro Arata

  BIOLOGICAL & PHARMACEUTICAL BULLETIN 40 10 1789 - 1795 2017年10月 [査読有り]
  
• Glucosamine Suppresses Osteoclast Differentiation through the Modulation of Glycosylation Including O-GlcNAcylation

  Tomoharu Takeuchi; Aya Sugimoto; Nao Imazato; Mayumi Tamura; Sachie Nakatani; Kenji Kobata; Yoichiro Arata

  BIOLOGICAL & PHARMACEUTICAL BULLETIN 40 3 352 - 356 2017年03月 [査読有り]
  
• N-acetylglucosamine suppresses osteoclastogenesis in part through the promotion of O-GlcNAcylation

  Tomoharu Takeuchi; Moyuko Nagasaka; Miyuki Shimizu; Mayumi Tamura; Yoichiro Arata

  Bone Reports 5 15 - 21 2016年12月 [査読有り]
  
• Identification of the cysteine residue responsible for oxidative inactivation of mouse galectin-2

  Mayumi Tamura; Akari Sasai; Rika Ozawa; Masanori Saito; Kaori Yamamoto; Tomoharu Takeuchi; Kazuo Ohtake; Hiroaki Tateno; Jun Hirabayashi; Jun Kobayashi; Yoichiro Arata

  JOURNAL OF BIOCHEMISTRY 160 4 233 - 241 2016年10月 [査読有り]
  
• Preparation of a polyclonal antibody that recognizes a unique galactoseβ1-4fucose disaccharide epitope.

  Takeuchi T; Nishiyama K; Saito S; Tamura M; Fuwa TJ; Nishihara S; Takahashi H; Natsugari H; Arata Y; Kasai K

  Carbohydrate research 412 50 - 55 2015年08月 [査読有り]
  
• Purification of galectin-1 mutants using an immobilized Galactoseβ1-4Fucose affinity adsorbent.

  Takeuchi T; Tamura M; Ishii N; Ishikida H; Sugimoto S; Suzuki D; Nishiyama K; Takahashi H; Natsugari H; Arata Y

  Protein expression and purification 111 82 - 86 2015年07月 [査読有り]
  
• ガレクチン-2のS-ニトロソ化による生化学的性質の変化の解析

  小澤 梨香; 田村 真由美; 齊藤 雅徳; 山本 香理; 武内 智春; 大竹 一男; 舘野 浩章; 平林 淳; 小林 順; 荒田 洋一郎

  日本薬学会年会要旨集 135年会 3 104 - 104 (公社)日本薬学会 2015年03月
• ISG15 Regulates RANKL-Induced Osteoclastogenic Differentiation of RAW264 Cells

  Tomoharu Takeuchi; Genki Shimakawa; Mayumi Tamura; Hideyoshi Yokosawa; Yoichiro Arata

  BIOLOGICAL & PHARMACEUTICAL BULLETIN 38 3 482 - 486 2015年03月 [査読有り]
  
• S-nitrosylation of mouse galectin-2 prevents oxidative inactivation by hydrogen peroxide

  Mayumi Tamura; Masanori Saito; Kaori Yamamoto; Tomoharu Takeuchi; Kazuo Ohtake; Hiroaki Tateno; Jun Hirabayashi; Jun Kobayashi; Yoichiro Arata

  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 457 4 712 - 717 2015年02月 [査読有り]
  
• Cross linking of Cys-Mutated Human Galectin-1 to the Model Glycoprotein Ligands Asialofetuin and Laminin by Using a Photoactivatable Bifunctional Reagent

  Mayumi Tamura; Tomoe Watanabe; Takanori Igarashi; Tomoharu Takeuchi; Ken-ichi Kasai; Yoichiro Arata

  BIOLOGICAL & PHARMACEUTICAL BULLETIN 37 5 877 - 882 2014年05月 [査読有り]
  
• Mammalian galectins bind galactoseβ1-4fucose disaccharide, a unique structural component of protostomial N-type glycoproteins.

  Takeuchi T; Tamura M; Nishiyama K; Iwaki J; Hirabayashi J; Takahashi H; Natsugari H; Arata Y; Kasai K

  Biochemical and biophysical research communications 436 3 509 - 513 2013年07月 [査読有り]
  
• Structural basis of preferential binding of fucose-containing saccharide by the Caenorhabditis elegans galectin LEC-6

  Hisayoshi Makyio; Tomoharu Takeuchi; Mayumi Tamura; Kazusa Nishiyama; Hideyo Takahashi; Hideaki Natsugari; Yoichiro Arata; Ken-Ichi Kasai; Yusuke Yamada; Soichi Wakatsuki; Ryuichi Kato

  Glycobiology 23 7 797 - 805 2013年07月 [査読有り]
  
• Caenorhabditis elegans proteins captured by immobilized Galβ1-4Fuc disaccharide units: assignment of 3 annexins.

  Takeuchi T; Nishiyama K; Yamada A; Tamura M; Takahashi H; Natsugari H; Aikawa J; Kojima-Aikawa K; Arata Y; Kasai K

  Carbohydrate research 346 13 1837 - 1841 2011年09月 [査読有り]
  
• Quantitative evaluation of lectin-reactive glycoforms of α(1)-acid glycoprotein using lectin affinity capillary electrophoresis with fluorescence detection.

  Shimura K; Tamura M; Toda T; Yazawa S; Kasai K

  Electrophoresis 32 16 2188 - 2193 2011年08月 [査読有り]
  
• Cross-Link Formation between Mutant Galectins of Caenorhabditis elegans with a Substituted Cysteine Residue and Asialofetuin via a Photoactivatable Bifunctional Reagent

  Mayumi Tamura; Tomoharu Takeuchi; Takamasa Nonaka; Ken-ichi Kasai; Yoichiro Arata

  BIOLOGICAL & PHARMACEUTICAL BULLETIN 34 6 929 - 932 2011年06月 [査読有り]
  
• Side Chain Orientation of the Amino Acid Substituted by a Cysteine Residue Is Important for Successful Crosslinking of Galectin to Its Glycoprotein Ligand Using a Photoactivatable Sulfhydryl Reagent

  Mayumi Tamura; Takanori Igarashi; Ken-ichi Kasai; Yoichiro Arata

  YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN 130 10 1375 - 1379 2010年10月 [査読有り]
  
• Crosslinking of N-acetyllactosamine-containing glycoproteins to galectin-1 with an introduced cysteine using a photoactivatable sulfhydryl reagent

  Mayumi Tamura; Takanori Igarashi; Ken-ichi Kasai; Yoichiro Arata

  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 390 3 581 - 584 2009年12月 [査読有り]
  
• Identification of a second, non-conserved amino acid that contributes to the unique sugar binding properties of the nematode galectin LEC-1

  Mayumi Tamura; Ken-ichi Kasai; Takashi Itagaki; Takamasa Nonaka; Yoichiro Arata

  BIOLOGICAL & PHARMACEUTICAL BULLETIN 31 6 1254 - 1257 2008年06月 [査読有り]
  
• Identification of the amino acid residue in the nematode galectin LEC-1 responsible for its unique sugar binding property: Analysis by combination of site-directed mutagenesis and frontal affinity chromatography

  Yolchiro Arata; Norihide Ishii; Mayurni Tamura; Takamasa Nonaka; Ken-Ichi Kasai

  BIOLOGICAL & PHARMACEUTICAL BULLETIN 30 11 2012 - 2017 2007年11月 [査読有り]
  
• Crosslinking of low-affinity glycoprotein ligands to galectin LEC-1 using a photoactivatable sulthydryl reagent

  Yoichiro Arata; Mayumi Tamura; Takamasa Nonaka; Ken-ichi Kasai

  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 350 1 185 - 190 2006年11月 [査読有り]
  

MISC

• 細胞外のガレクチン-1が破骨細胞分化を抑制する

  武内智春; 大山翠; 田村真由美; 荒田洋一郎; 畑中朋美; 畑中朋美 日本糖質学会年会要旨集 42nd 2023年
• ガレクチン-8の酸化が赤血球凝集活性試験に与える影響

  田村真由美; 肥留間絢美; 渡邊里佳子; 岡沙織; 武内智春; 畑中朋美; 畑中朋美; 荒田洋一郎 日本薬学会年会要旨集(Web) 143rd 2023年
• GFP付加ガレクチン-2を用いた胃粘膜中のリガンド局在部位の検討

  田村真由美; 岡沙織; 谷川尚; 小林純子; 荒田洋一郎 日本薬学会年会要旨集(Web) 142nd 2022年
• マウスガレクチン-2の胃粘液中のリガンドの同定

  田村真由美; 田中享; 藤井智彦; 谷川尚; 岡沙織; 武内智春; 畑中朋美; 畑中朋美; 岸本成史; 荒田洋一郎 日本薬学会年会要旨集(Web) 140th 2020年