Kunugi Hiroshi

Researcher Information

Affiliation

Clinical Medicine Professor and Chairman
Department of Neuropsychiatry Professor and Chairman

Degree

• Ph.D.（1994/06 The University of Tokyo）

URL

https://jglobal.jst.go.jp/detail?JGLOBAL_ID=200901005772392630

J-Global ID

• 200901005772392630

Profile

• 統合失調症と気分障害の生物学的研究を行い、バイオマーカーと新たな治療法の開発を行っています。最近は、脳脊髄液をバイオリソースとした研究、食品成分の精神疾患治療への応用（精神栄養学）に関する研究を中心に行っています。

Research Interests

• mood disorders   nutritional psychiatry   cerebrospinal fluid   gut microbiota   life style   脳由来神経栄養因子   stress   視床下部ー下垂体－副腎系   heart rate variability   統合失調症   プレパルス抑制テスト   モデル動物   Alzheimer's disease   遺伝子多型   psychopharmacology   神経科学   VEGF   cognitive function   分子遺伝学   海馬   神経栄養因子   神経発達障害   

Research Areas

• Life sciences / Psychiatry
• Life sciences / Nutrition and health science
• Life sciences / Genetics

Academic & Professional Experience

• 2021/04 - Today  Teikyo University School of MedicineDepartment of PsychiatryProfessor and Chair
• 2020/04 - Today  National Center of Neurology and Psychiatry
• 2020/04 - Today  Teikyo University
• 2020/04 - Today  National Center of Neurology and PsychiatryDepartment of Mental Disorder ResearchVisiting researcher
• 2002/05 - 2020/03  National Center of Neurology and PsychiatryDepartment of Mental Disorder ResearchDirector
• 1998/01 - 2002/05  Teikyo University
• 1991/04 - 1997/12  Teikyo UniversitySchool of Medicine, Department of Psychiatry and Neurologyassistant

Education

• 1980/04 - 1982/03  The University of Tokyo  College of Arts and Sciences

Association Memberships

• Japanese Society for Child and Adolescent Psychiatry   東京精神医学会   Japanese Society of Nutrition and Food Science   International College of Neuropsychopharmacology   Japanese Clinical Nutrition Association   Japanese Society of Clinical Nutrition   Japanese Society of Mood Disorders   日本統合失調症学会   日本臨床精神神経薬理学会   Japanese Society of Neuroscience   Japanese Society of Sleep Research   Japanese Society of Geriatric Psychiatry   Japanese Society of Biological Psychiatry   日本社会精神医学会   Japanese Society of General Hospital Psychiatry   Japanese Society of Psychiatry and Neurology   日本神経精神薬理学会   

Research Activity Information

Published Papers

• Blood brain barrier disruption in the pathophysiology of depression

  Matsuno H; Kunugi H

  Japanese Journal of Clinical Psychiatry 53 (4) 479 - 484 2024/04 [Invited]
  
• Blood mRNA expression levels of glucocorticoid receptors and FKBP5 are associated with depressive disorder and altered HPA axis.

  Hiroaki Hori; Fuyuko Yoshida; Ikki Ishida; Junko Matsuo; Shintaro Ogawa; Kotaro Hattori; Yoshiharu Kim; Hiroshi Kunugi

  Journal of affective disorders 349 244 - 253 2024/03
• Nutritional factors and interventions in depressive disorder

  Midori Hashimoto; Hiroshi Kunugi

  Clinical Psychiatry 66 (3) 263 - 267 2024/03 [Invited]
  
• Nutritional problems in modern diet

  Hiroshi Kunugi

  Clinical Psychiatry 66 (3) 242 - 246 2024/03 [Invited]
  
• Fear memory regulation by the cAMP signaling pathway as an index of reexperiencing symptoms in posttraumatic stress disorder.

  Hiroaki Hori; Hotaka Fukushima; Taikai Nagayoshi; Rie Ishikawa; Min Zhuo; Fuyuko Yoshida; Hiroshi Kunugi; Kenichi Okamoto; Yoshiharu Kim; Satoshi Kida

  Molecular psychiatry 2024/02
• Biomarkers of hypothalamic-pituitary-adrenal axis in depressive disorder

  功刀浩

  Clinical Psychiatry 66 (3) 241 - 241 2024/02 [Invited]
  
• Biomarkers of hypothalamic-pituitary-adrenal axis in depressive disorder

  Hiroshi Kunugi

  Clinical Psychiatry 66 (2) 151 - 155 2024/02 [Invited]
  
• 臨床的エビデンスを中心にうつ病患者の腸内細菌を見る

  功刀浩

  Microbiome Science 2 (4) 218 - 233 2023/10 [Invited]
  
• Current status;future directions of;research on pathophysiology of;psychiatric diseases for;drug discovery;a narrative review;focusing on schizophrenia

  Kunugi Hiroshi

  Jap J Clin Psychopharmacol 26 (10) 927 - 936 2023/10 [Invited]
  
• Dietary habits to prevent and ameliorate lifestyle diseases in psychiatric patients

  Hiroshi Kunugi

  Jap J Psychiatr Treat 38 (9) 999 - 104 2023/09 [Invited]
  
• Depression and lifestyle: Focusing on nutrition, exercise, and their possible relevance to molecular mechanisms.

  Hiroshi Kunugi

  Psychiatry and clinical neurosciences 77 (8) 420 - 433 2023/08
• Suicidality in civilian women with PTSD: Possible link to childhood maltreatment, proinflammatory molecules, and their genetic variations

  Hitomi Kawanishi; Hiroaki Hori; Fuyuko Yoshida; Mariko Itoh; Mingming Lin; Madoka Niwa; Megumi Narita; Takeshi Otsuka; Keiko Ino; Risa Imai; Shin Fukudo; Toshiko Kamo; Hiroshi Kunugi; Yoshiharu Kim

  Brain, Behavior, & Immunity - Health Elsevier BV 30 100650 - 100650 2666-3546 2023/07
• Possible involvement of Interleukin‐17A in the deterioration of prepulse inhibition on acoustic startle response in mice

  Chisato Wakabayashi; Hiroshi Kunugi

  Neuropsychopharmacology Reports Wiley 2574-173X 2023/06
• Discrepancy between Clinician-rated and Self-reported Depression Severity is Associated with Adverse Childhood Experience, Autistic-like Traits, and Coping Styles in Mood Disorders

  Risa Yamada; Takeshi Fujii; Kotaro Hattori; Hiroaki Hori; Ryo Matsumura; Tomoko Kurashimo; Naoko Ishihara; Sumiko Yoshida; Tomiki Sumiyoshi; Hiroshi Kunugi

  Clinical Psychopharmacology and Neuroscience Korean College of Neuropsychopharmacology 21 (2) 296 - 303 1738-1088 2023/05
• Variability and magnitude of brain glutamate levels in schizophrenia: a meta and mega-analysis.

  Kate Merritt; Robert A McCutcheon; André Aleman; Sarah Ashley; Katherine Beck; Wolfgang Block; Oswald J N Bloemen; Faith Borgan; Christiana Boules; Juan R Bustillo; Aristides A Capizzano; Jennifer M Coughlin; Anthony David; Camilo de la Fuente-Sandoval; Arsime Demjaha; Kara Dempster; Kim Q Do; Fei Du; Peter Falkai; Beata Galińska-Skok; Jürgen Gallinat; Charles Gasparovic; Cedric E Ginestet; Naoki Goto; Ariel Graff-Guerrero; Beng-Choon Ho; Oliver Howes; Sameer Jauhar; Peter Jeon; Tadafumi Kato; Charles A Kaufmann; Lawrence S Kegeles; Matcheri S Keshavan; Sang-Young Kim; Bridget King; Hiroshi Kunugi; J Lauriello; Pablo León-Ortiz; Edith Liemburg; Meghan E Mcilwain; Gemma Modinos; Elias Mouchlianitis; Jun Nakamura; Igor Nenadic; Dost Öngür; Miho Ota; Lena Palaniyappan; Christos Pantelis; Tulsi Patel; Eric Plitman; Sotirios Posporelis; Scot E Purdon; Jürgen R Reichenbach; Perry F Renshaw; Francisco Reyes-Madrigal; Bruce R Russell; Akira Sawa; Martin Schaefer; Dikoma C Shungu; Stefan Smesny; Jeffrey A Stanley; James Stone; Agata Szulc; Reggie Taylor; Katharine N Thakkar; Jean Théberge; Philip G Tibbo; Thérèse van Amelsvoort; Jerzy Walecki; Peter C Williamson; Stephen J Wood; Lijing Xin; Hidenori Yamasue; Philip McGuire; Alice Egerton

  Molecular psychiatry 28 (5) 2039 - 2048 2023/05
• Analyzing schizophrenia-related phenotypes in mice caused by autoantibodies against NRXN1α in schizophrenia.

  Hiroki Shiwaku; Shingo Katayama; Mengxuan Gao; Kanoh Kondo; Yuri Nakano; Yukiko Motokawa; Saori Toyoda; Fuyuko Yoshida; Hiroaki Hori; Tetsuo Kubota; Kinya Ishikawa; Hiroshi Kunugi; Yuji Ikegaya; Hitoshi Okazawa; Hidehiko Takahashi

  Brain, behavior, and immunity 111 32 - 45 2023/03
• Reduced homovanillic acid, SDF-1α and SCGF-β levels in cerebrospinal fluid are related to depressive states in systemic lupus erythematosus

  Yuya Fujita; Shigeru Iwata; Shinsuke Hidese; Sayuri Ishiwata; Satoru Ide; Hiroaki Tanaka; Koshiro Sonomoto; Yusuke Miyazaki; Shingo Nakayamada; Atsuko Ikenouchi; Kotaro Hattori; Hiroshi Kunugi; Reiji Yoshimura; Yoshiya Tanaka

  Rheumatology Oxford University Press (OUP) 1462-0324 2023/02
• Characteristic association of symbol coding test score with occupational function in Japanese patients with schizophrenia

  Yukako Watanabe; Sho Kanata; Motomu Suga; Akiko Inagaki; Sayaka Sato; Naoki Hayashi; Hiroshi Kunugi; Emi Ikebuchi

  Neuropsychopharmacology Reports Wiley 43 (1) 141 - 145 2574-173X 2023/02
• 食生活習慣とうつ病リスク—Dietary habits and risk of depressive disorder—特集 疾病予防・健康寿命延伸に資する栄養・食生活とは? ; 疾患発症予防に関わる栄養・食生活

  功刀 浩

  医学のあゆみ 医歯薬出版 284 (1) 33 - 38 0039-2359 2023/01
• Association between the Pittsburgh sleep quality index and white matter integrity in healthy adults: a whole-brain magnetic resonance imaging study

  Shinsuke Hidese; Miho Ota; Junko Matsuo; Ikki Ishida; Yuuki Yokota; Kotaro Hattori; Yukihito Yomogida; Hiroshi Kunugi

  Sleep and Biological Rhythms Springer Science and Business Media LLC 1446-9235 2023/01
• Plasma neuropeptide levels in patients with schizophrenia, bipolar disorder, or major depressive disorder and healthy controls: A multiplex immunoassay study

  Shinsuke Hidese; Fuyuko Yoshida; Ikki Ishida; Junko Matsuo; Kotaro Hattori; Hiroshi Kunugi

  Neuropsychopharmacology Reports Wiley 2574-173X 2022/11
• うつ病のマイクロバイオーム研究 : 特に腸内細菌叢と病態メカニズムの関連について—Microbiome research in depressive disorder : focus on gut microbiome and its relation with pathophysiology—特集 臨床につながる気分障害研究最前線

  小方 茂弘; 功刀 浩

  臨床精神医学 = Japanese journal of clinical psychiatry アークメディア 51 (10) 1131 - 1138 0300-032X 2022/10
• Association of body mass index and its classifications with gray matter volume in individuals with a wide range of body mass index group: A whole-brain magnetic resonance imaging study

  Shinsuke Hidese; Miho Ota; Junko Matsuo; Ikki Ishida; Yuuki Yokota; Kotaro Hattori; Yukihito Yomogida; Hiroshi Kunugi

  Frontiers in Human Neuroscience Frontiers Media SA 16 2022/09
• A preliminary study on predictors of treatment response to repetitive transcranial magnetic stimulation in patients with treatment‐resistant depression in Japan

  Haruki Ikawa; Mamoru Tochigi; Yoshihiro Noda; Hiroshi Oba; Tatsuro Kaminaga; Keita Sakurai; Emi Ikebuchi; Naoki Hayashi; Hiroshi Kunugi

  Neuropsychopharmacology Reports Wiley 2574-173X 2022/08
• 治療抵抗性うつ病の病態生理—Pathophysiology of difficult-to-treat depression—治療抵抗性うつ病への挑戦

  功刀 浩

  精神科治療学 / 「精神科治療学」編集委員会 編 星和書店 37 (8) 823 - 828 0912-1862 2022/08
• Simultaneous monitoring of activity and heart rate variability in depressed patients: A pilot study using a wearable monitor for 3 consecutive days

  Norie Koga; Yoko Komatsu; Ryo Shinozaki; Ikki Ishida; Yusuke Shimizu; Sonoko Ishimaru; Hiroshi Kunugi

  Neuropsychopharmacology Reports Wiley 42 (4) 457 - 467 2574-173X 2022/07
• PTSD女性患者における自殺リスク 幼少期被虐待体験、炎症マーカー、炎症系遺伝子多型との関連

  河西 ひとみ; 堀 弘明; 吉田 冬子; 伊藤 真利子; 林 明明; 丹羽 まどか; 井野 敬子; 今井 理紗; 関口 敦; 加茂 登志子; 功刀 浩; 金 吉晴

  国立精神・神経医療研究センター精神保健研究所年報 (国研)国立精神・神経医療研究センター精神保健研究所 (35) 195 - 195 2022/06
• Relationship between Interpersonal Sensitivity Measure score and clinical symptoms in patients with major psychiatric disorders and healthy individuals

  Shinsuke Hidese; Junko Matsuo; Ikki Ishida; Yuuki Yokota; Miho Ota; Kotaro Hattori; Hiroshi Kunugi

  Psychiatry and Clinical Neurosciences Reports Wiley 1 (2) 2769-2558 2022/06
• Association between vascular endothelial growth factor-mediated blood-brain barrier dysfunction and stress-induced depression.

  Hitomi Matsuno; Shoko Tsuchimine; Kazunori O'Hashi; Kazuhisa Sakai; Kotaro Hattori; Shinsuke Hidese; Shingo Nakajima; Shuichi Chiba; Aya Yoshimura; Noriko Fukuzato; Mayumi Kando; Megumi Tatsumi; Shintaro Ogawa; Noritaka Ichinohe; Hiroshi Kunugi; Kazuhiro Sohya

  Molecular psychiatry 2022/05
• Haplotype phasing of a bipolar disorder pedigree revealed rare multiple mutations of SPOCD1 gene in the 1p36-35 susceptibility locus.

  Gakuya Takamatsu; Kumiko Yanagi; Kae Koganebuchi; Fuyuko Yoshida; Jun-Seok Lee; Kanako Toyama; Kotaro Hattori; Chiaki Katagiri; Tsuyoshi Kondo; Hiroshi Kunugi; Ryosuke Kimura; Tadashi Kaname; Masayuki Matsushita

  Journal of affective disorders 310 96 - 105 2022/05
• Improving polygenic prediction in ancestrally diverse populations

  Yunfeng Ruan; Yen-Feng Lin; Yen-Chen Anne Feng; Chia-Yen Chen; Max Lam; Zhenglin Guo; Yong Min Ahn; Kazufumi Akiyama; Makoto Arai; Ji Hyun Baek; Wei J. Chen; Young-Chul Chung; Gang Feng; Kumiko Fujii; Stephen J. Glatt; Kyooseob Ha; Kotaro Hattori; Teruhiko Higuchi; Akitoyo Hishimoto; Kyung Sue Hong; Yasue Horiuchi; Hai-Gwo Hwu; Masashi Ikeda; Sayuri Ishiwata; Masanari Itokawa; Nakao Iwata; Eun-Jeong Joo; Rene S. Kahn; Sung-Wan Kim; Se Joo Kim; Se Hyun Kim; Makoto Kinoshita; Hiroshi Kunugi; Agung Kusumawardhani; Jimmy Lee; Byung Dae Lee; Heon-Jeong Lee; Jianjun Liu; Ruize Liu; Xiancang Ma; Woojae Myung; Shusuke Numata; Tetsuro Ohmori; Ikuo Otsuka; Yuji Ozeki; Sibylle G. Schwab; Wenzhao Shi; Kazutaka Shimoda; Kang Sim; Ichiro Sora; Jinsong Tang; Tomoko Toyota; Ming Tsuang; Dieter B. Wildenauer; Hong-Hee Won; Takeo Yoshikawa; Alice Zheng; Feng Zhu; Lin He; Akira Sawa; Alicia R. Martin; Shengying Qin; Hailiang Huang; Tian Ge

  Nature Genetics Springer Science and Business Media LLC 54 (5) 573 - 580 1061-4036 2022/05 [Refereed]
  
• 統合失調症の対人機能・労働機能に寄与する要因 認知機能や精神症状との関連

  渡邊 由香子; 金田 渉; 佐藤 研一; 稲垣 晃子; 管 心; 佐藤 さやか; 林 直樹; 功刀 浩; 池淵 恵美

  精神神経学雑誌 (公社)日本精神神経学会 124 (4付録) S - 545 0033-2658 2022/04
• The Bergen Facebook Addiction Scale: its psychometric properties and invariance among women with eating disorders.

  Amira Mohammed Ali; Amin Omar Hendawy; Eman Sameh Abd Elhay; Esraa Mohammed Ali; Abdulmajeed A Alkhamees; Hiroshi Kunugi; Nagia I Hassan

  BMC women's health 22 (1) 99 - 99 2022/03
• Acute and chronic effects of oral administration of a medium-chain fatty acid, capric acid, on locomotor activity and anxiety-like and depression-related behaviors in adult male C57BL/6J mice.

  Hirotaka Shoji; Hiroshi Kunugi; Tsuyoshi Miyakawa

  Neuropsychopharmacology reports 42 (1) 59 - 69 2022/03
• Gut permeability and its clinical relevance in schizophrenia.

  Ikki Ishida; Jun Ogura; Emiko Aizawa; Miho Ota; Shinsuke Hidese; Yukihito Yomogida; Junko Matsuo; Sumiko Yoshida; Hiroshi Kunugi

  Neuropsychopharmacology reports 42 (1) 70 - 76 2022/03
• Relationship of food allergy with quality of life and sleep in psychiatric patients.

  Chiho Gomi; Yuuki Yokota; Sumiko Yoshida; Hiroshi Kunugi

  Neuropsychopharmacology reports 42 (1) 84 - 91 2022/03
• Association of childhood maltreatment history with salivary interleukin-6 diurnal patterns and C-reactive protein in healthy adults.

  Hiroaki Hori; Shuhei Izawa; Fuyuko Yoshida; Hiroshi Kunugi; Yoshiharu Kim; Shinya Mizukami; Yusuke Inoue; Hirokuni Tagaya; Yuko Hakamata

  Brain, behavior, and immunity 101 377 - 382 2022/03
• Psychological Distress and Personality Dimensions Associated with Romantic Orientation Among Japanese Adults.

  Daimei Sasayama; Miyuki Chijiiwa; Shun Nogawa; Kenji Saito; Hiroshi Kunugi

  LGBT health 2022/01
• Hypothalamic-pituitary-adrenal axis and renin-angiotensin-aldosterone system in adulthood PTSD and childhood maltreatment history.

  Ryoko Kakehi; Hiroaki Hori; Fuyuko Yoshida; Mariko Itoh; Mingming Lin; Madoka Niwa; Megumi Narita; Keiko Ino; Risa Imai; Daimei Sasayama; Toshiko Kamo; Hiroshi Kunugi; Yoshiharu Kim

  Frontiers in psychiatry 13 967779 - 967779 2022
• The cerebellum as a moderator of negative bias of facial expression processing in depressive patients

  Anna Nakamura; Yukihito Yomogida; Miho Ota; Junko Matsuo; Ikki Ishida; Shinsuke Hidese; Hiroshi Kunugi

  Journal of Affective Disorders Reports Elsevier BV 7 100295 - 100295 2666-9153 2022/01
• Recent advances in understanding depressive disorder: Possible relevance to brain stimulation therapies.

  Hiroshi Kunugi; Maria Tikhonova

  Progress in brain research 270 (1) 123 - 147 2022
• The Depression Anxiety Stress Scale 8-Items Expresses Robust Psychometric Properties as an Ideal Shorter Version of the Depression Anxiety Stress Scale 21 Among Healthy Respondents From Three Continents.

  Amira Mohammed Ali; Hiroaki Hori; Yoshiharu Kim; Hiroshi Kunugi

  Frontiers in psychology 13 799769 - 799769 2022
• The Six-Item Version of the Internet Addiction Test: Its Development, Psychometric Properties, and Measurement Invariance among Women with Eating Disorders and Healthy School and University Students.

  Amira Mohammed Ali; Amin Omar Hendawy; Abdulaziz Mofdy Almarwani; Naif Alzahrani; Nashwa Ibrahim; Abdulmajeed A Alkhamees; Hiroshi Kunugi

  International journal of environmental research and public health 18 (23) 2021/11
• The Depression Anxiety Stress Scale 21: Development and Validation of the Depression Anxiety Stress Scale 8-Item in Psychiatric Patients and the General Public for Easier Mental Health Measurement in a Post COVID-19 World.

  Amira Mohammed Ali; Abdulmajeed A Alkhamees; Hiroaki Hori; Yoshiharu Kim; Hiroshi Kunugi

  International journal of environmental research and public health 18 (19) 2021/09
• 健常成人における自閉症スペクトラム傾向とWAIS-IIIのプロフィール

  松尾 淳子; 石田 一希; 太田 深秀; 秀瀬 真輔; 堀 弘明; 蓬田 幸人; 神尾 陽子; 功刀 浩

  精神神経学雑誌 (公社)日本精神神経学会 (2021特別号) S593 - S593 0033-2658 2021/09
• Neuroanatomical basis of harm avoidance personality traits in major depressive disorder

  Yukihito Yomogida; Miho Ota; Junko Matsuo; Ikki Ishida; Shinsuke Hidese; Toshiya Teraishi; Noriko Sato; Hiroshi Matsuda; Kotaro Hattori; Hiroshi Kunugi

  Journal of Affective Disorders Reports Elsevier BV 100225 - 100225 2666-9153 2021/09
• [Intestinal Flora and Mental Disorders: A Focus on Mood Disorders and Autism Spectrum Disorder].

  Hiroshi Kunugi

  Brain and nerve = Shinkei kenkyu no shinpo 株式会社医学書院 73 (8) 871 - 877 1881-6096 2021/08
• Reduced cerebrospinal fluid levels of lysophosphatidic acid docosahexaenoic acid (LPA-DHA) in patients with major depressive disorder and schizophrenia.

  Wataru Omori; Kuniyuki Kano; Kotaro Hattori; Naoto Kajitani; Mami Okada Tsuchioka; Shuken Boku; Hiroshi Kunugi; Junken Aoki; Minoru Takebayashi

  The international journal of neuropsychopharmacology 24 (12) 948 - 955 2021/07
• An fMRI Investigation into the Effects of Ketogenic Medium-Chain Triglycerides on Cognitive Function in Elderly Adults: A Pilot Study.

  Yukihito Yomogida; Junko Matsuo; Ikki Ishida; Miho Ota; Kentaro Nakamura; Kinya Ashida; Hiroshi Kunugi

  Nutrients 13 (7) 2021/06
• Association of Age, Antipsychotic Medication, and Symptom Severity in Schizophrenia With Proton Magnetic Resonance Spectroscopy Brain Glutamate Level: A Mega-analysis of Individual Participant-Level Data.

  Kate Merritt; Philip K McGuire; Alice Egerton; André Aleman; Wolfgang Block; Oswald J N Bloemen; Faith Borgan; Juan R Bustillo; Aristides A Capizzano; Jennifer Marie Coughlin; Camilo De la Fuente-Sandoval; Arsime Demjaha; Kara Dempster; Kim Q Do; Fei Du; Peter Falkai; Beata Galinska-Skok; Jurgen Gallinat; Charles Gasparovic; Cedric E Ginestet; Naoki Goto; Ariel Graff-Guerrero; Beng Choon Ho; Oliver D Howes; Sameer Jauhar; Peter Jeon; Tadafumi Kato; Charles A Kaufmann; Lawrence S Kegeles; Matcheri Keshavan; Sang-Young Kim; Hiroshi Kunugi; John Lauriello; Edith Jantine Liemburg; Meghan E Mcilwain; Gemma Modinos; Elias D Mouchlianitis; Jun Nakamura; Igor Nenadic; Dost Öngür; Miho Ota; Lena Palaniyappan; Christos Pantelis; Eric Plitman; Sotirios Posporelis; Scot E Purdon; Jürgen R Reichenbach; Perry F Renshaw; Bruce R Russell; Akira Sawa; Martin Schaefer; Dikoma C Shungu; Stefan Smesny; Jeffrey A Stanley; James M Stone; Agata Szulc; Reggie Taylor; Katy Thakkar; Jean Théberge; Philip G Tibbo; Therese van Amelsvoort; Jerzy Walecki; Peter C Williamson; Stephen James Wood; Lijing Xin; Hidenori Yamasue

  JAMA psychiatry 78 (6) 667 - 681 2021/06
• Childhood maltreatment history and attention bias variability in healthy adult women: role of inflammation and the BDNF Val66Met genotype

  Hiroaki Hori; Mariko Itoh; Mingming Lin; Fuyuko Yoshida; Madoka Niwa; Yuko Hakamata; Mie Matsui; Hiroshi Kunugi; Yoshiharu Kim

  Translational Psychiatry Springer Science and Business Media LLC 11 (1) 122 - 122 2021/06
• Effect of Lacticaseibacillus paracasei Strain Shirota on Improvement in Depressive Symptoms, and Its Association with Abundance of Actinobacteria in Gut Microbiota

  Machiko Otaka; Hiroko Kikuchi-Hayakawa; Jun Ogura; Hiroshi Ishikawa; Yukihito Yomogida; Miho Ota; Shinsuke Hidese; Ikki Ishida; Masanori Aida; Kazunori Matsuda; Mitsuhisa Kawai; Sumiko Yoshida; Hiroshi Kunugi

  Microorganisms MDPI AG 9 (5) 1026 - 1026 2021/05
• Profiling of Cerebrospinal Fluid Lipids and Their Relationship with Plasma Lipids in Healthy Humans

  Kosuke Saito; Kotaro Hattori; Shinsuke Hidese; Daimei Sasayama; Tomoko Miyakawa; Ryo Matsumura; Megumi Tatsumi; Yuuki Yokota; Miho Ota; Hiroaki Hori; Hiroshi Kunugi

  Metabolites MDPI AG 11 (5) 268 - 268 2021/04
• Hypoproteinemia predicts disease severity and mortality in COVID-19: a call for action.

  Amira Mohammed Ali; Hiroshi Kunugi

  Diagnostic pathology 16 (1) 31 - 31 2021/04
• Skeletal Muscle Damage in COVID-19: A Call for Action.

  Amira Mohammed Ali; Hiroshi Kunugi

  Medicina (Kaunas, Lithuania) 57 (4) 2021/04
• The Arabic Version of the Cohen Perceived Stress Scale: Factorial Validity and Measurement Invariance.

  Amira Mohammed Ali; Amin Omar Hendawy; Ohoud Ahmad; Haleama Al Sabbah; Linda Smail; Hiroshi Kunugi

  Brain sciences 11 (4) 2021/03
• Approaches to Nutritional Screening in Patients with Coronavirus Disease 2019 (COVID-19).

  Amira Mohammed Ali; Hiroshi Kunugi

  International journal of environmental research and public health 18 (5) 2021/03
• Propolis, Bee Honey, and Their Components Protect against Coronavirus Disease 2019 (COVID-19): A Review of In Silico, In Vitro, and Clinical Studies.

  Amira Mohammed Ali; Hiroshi Kunugi

  Molecules (Basel, Switzerland) 26 (5) 2021/02
• Cerebrospinal Fluid Inflammatory Cytokine Levels in Patients With Major Psychiatric Disorders: A Multiplex Immunoassay Study

  Shinsuke Hidese; Kotaro Hattori; Daimei Sasayama; Takuya Tsumagari; Tomoko Miyakawa; Ryo Matsumura; Yuuki Yokota; Ikki Ishida; Junko Matsuo; Sumiko Yoshida; Miho Ota; Hiroshi Kunugi

  Frontiers in Pharmacology Frontiers Media SA 11 594394 - 594394 2021/02
• Small noncoding vault RNA modulates synapse formation by amplifying MAPK signaling

  Shuji Wakatsuki; Yoko Takahashi; Megumi Shibata; Naoki Adachi; Tadahiro Numakawa; Hiroshi Kunugi; Toshiyuki Araki

  Journal of Cell Biology Rockefeller University Press 220 (2) 0021-9525 2021/02
• Association of CRP genetic variation with symptomatology, cognitive function, and circulating proinflammatory markers in civilian women with PTSD

  Takeshi Otsuka; Hiroaki Hori; Fuyuko Yoshida; Mariko Itoh; Mingming Lin; Madoka Niwa; Keiko Ino; Risa Imai; Sei Ogawa; Mie Matsui; Toshiko Kamo; Hiroshi Kunugi; Yoshiharu Kim

  Journal of Affective Disorders 279 640 - 649 0165-0327 2021/01
• Screening for Sarcopenia (Physical Frailty) in the COVID-19 Era.

  Amira Mohammed Ali; Hiroshi Kunugi

  International journal of endocrinology 2021 5563960 - 5563960 2021
• Gut Microbiota and Pathophysiology of Depressive Disorder.

  Hiroshi Kunugi

  Annals of nutrition & metabolism 77 Suppl 2 11 - 20 2021
• Predictors of Nutritional Status, Depression, Internet Addiction, Facebook Addiction, and Tobacco Smoking Among Women With Eating Disorders in Spain.

  Amira Mohammed Ali; Hiroaki Hori; Yoshiharu Kim; Hiroshi Kunugi

  Frontiers in psychiatry 12 735109 - 735109 2021
• Sirtuin 6 is a regulator of dendrite morphogenesis in rat hippocampal neurons

  Hitomi Matsuno; Shoko Tsuchimine; Noriko Fukuzato; Kazunori O’Hashi; Hiroshi Kunugi; Kazuhiro Sohya

  Neurochemistry International Elsevier BV 145 104959 - 104959 0197-0186 2021/01
• Performance on the Wechsler Adult Intelligence Scale ( WAIS ) in Japanese patients with bipolar and major depressive disorders in euthymic and depressed states

  Junko Matsuo; Hiroaki Hori; Ikki Ishida; Moeko Hiraishi; Miho Ota; Shinsuke Hidese; Yukihito Yomogida; Hiroshi Kunugi

  Psychiatry and Clinical Neurosciences Wiley 75 (4) 128 - 137 1323-1316 2020/12
• Structural brain network differences in bipolar disorder using with similarity-based approach

  Miho Ota; Takamasa Noda; Noriko Sato; Shinsuke Hidese; Toshiya Teraishi; Hiroshi Matsuda; Hiroshi Kunugi

  Acta Neuropsychiatrica Cambridge University Press (CUP) 33 (3) 1 - 26 0924-2708 2020/12
• Intermittent Fasting, Dietary Modifications, and Exercise for the Control of Gestational Diabetes and Maternal Mood Dysregulation: A Review and a Case Report.

  Amira Mohammed Ali; Hiroshi Kunugi

  International journal of environmental research and public health 17 (24) 2020/12
• COVID-19: A pandemic that threatens physical and mental health by promoting physical inactivity.

  Amira Mohammed Ali; Hiroshi Kunugi

  Sports medicine and health science 2 (4) 221 - 223 2020/12
• Royal Jelly as an Intelligent Anti-Aging Agent-A Focus on Cognitive Aging and Alzheimer's Disease: A Review.

  Amira Mohammed Ali; Hiroshi Kunugi

  Antioxidants (Basel, Switzerland) 9 (10) 2020/09
• Apitherapy for Age-Related Skeletal Muscle Dysfunction (Sarcopenia): A Review on the Effects of Royal Jelly, Propolis, and Bee Pollen.

  Amira Mohammed Ali; Hiroshi Kunugi

  Foods (Basel, Switzerland) 9 (10) 2020/09
• 双極性障害と大うつ病性障害患者の認知機能

  松尾 淳子; 石田 一希; 平石 萌子; 太田 深秀; 秀瀬 真輔; 堀 弘明; 寺石 俊哉; 蓬田 幸人; 功刀 浩

  精神神経学雑誌 (公社)日本精神神経学会 (2020特別号) S447 - S447 0033-2658 2020/09
• 経頭蓋磁気刺激による治療抵抗性うつ病の治療と局所脳血流量変化の検討

  井川 春樹; 栃木 衛; 櫻井 圭太; 神長 達郎; 赤羽 晃寿; 池淵 恵美; 大場 洋; 功刀 浩; 林 直樹

  日本神経精神薬理学会年会・日本生物学的精神医学会年会・日本精神薬学会総会・学術集会合同年会プログラム・抄録集 日本神経精神薬理学会・日本生物学的精神医学会・日本精神薬学会 50回・42回・4回 181 - 181 2020/08
• Association between obesity and white matter microstructure impairments in patients with schizophrenia: A whole-brain magnetic resonance imaging study

  Shinsuke Hidese; Miho Ota; Junko Matsuo; Ikki Ishida; Yuuki Yokota; Kotaro Hattori; Yukihito Yomogida; Hiroshi Kunugi

  Schizophrenia Research Elsevier BV 230 108 - 110 0920-9964 2020/08
• Lower cerebrospinal fluid CRH concentration in chronic schizophrenia with negative symptoms.

  Sayuri Ishiwata; Kotaro Hattori; Shinsuke Hidese; Daimei Sasayama; Tomoko Miyakawa; Ryo Matsumura; Yuuki Yokota; Sumiko Yoshida; Hiroshi Kunugi

  Journal of psychiatric research 127 13 - 19 2020/08
• Increased matrix metalloproteinases in cerebrospinal fluids of patients with major depressive disorder and schizophrenia.

  Wataru Omori; Kotaro Hattori; Naoto Kajitani; Mami Okada- Tsuchioka; Shuken Boku; Hiroshi Kunugi; Yasumasa Okamoto; Minoru Takebayashi

  The international journal of neuropsychopharmacology 23 (11) 713 - 20 2020/07
• AUTS2 Regulation of Synapses for Proper Synaptic Inputs and Social Communication.

  Kei Hori; Kunihiko Yamashiro; Taku Nagai; Wei Shan; Saki F Egusa; Kazumi Shimaoka; Hiroshi Kuniishi; Masayuki Sekiguchi; Yasuhiro Go; Shoji Tatsumoto; Mitsuyo Yamada; Reika Shiraishi; Kouta Kanno; Satoshi Miyashita; Asami Sakamoto; Manabu Abe; Kenji Sakimura; Masaki Sone; Kazuhiro Sohya; Hiroshi Kunugi; Keiji Wada; Mitsuhiko Yamada; Kiyofumi Yamada; Mikio Hoshino

  iScience 23 (6) 101183 - 101183 2020/06 [Refereed]
  
• Correlation Between the Wechsler Adult Intelligence Scale- 3rd Edition Metrics and Brain Structure in Healthy Individuals: A Whole-Brain Magnetic Resonance Imaging Study

  Shinsuke Hidese; Miho Ota; Junko Matsuo; Ikki Ishida; Moeko Hiraishi; Yuuki Yokota; Kotaro Hattori; Yukihito Yomogida; Hiroshi Kunugi

  Frontiers in Human Neuroscience Frontiers Media SA 14 291 - 291 2020/06
• Possible associations between plasma fibroblast growth factor 21 levels and cognition in bipolar disorder

  Favour Omileke; Sayuri Ishiwata; Junko Matsuo; Fuyuko Yoshida; Shinsuke Hidese; Kotaro Hattori; Hiroshi Kunugi

  Neuropsychopharmacology Reports Wiley 40 (2) 175 - 181 2574-173X 2020/06
• Increased apolipoprotein E and decreased TNF-α in the cerebrospinal fluid of nondemented APOE-ε4 carriers.

  Daimei Sasayama; Kotaro Hattori; Yuuki Yokota; Ryo Matsumura; Toshiya Teraishi; Sumiko Yoshida; Hiroshi Kunugi

  Neuropsychopharmacology reports 40 (2) 201 - 205 2020/06
• Cerebrospinal fluid neuroplasticity-associated protein levels in patients with psychiatric disorders: a multiplex immunoassay study.

  Shinsuke Hidese; Kotaro Hattori; Daimei Sasayama; Takuya Tsumagari; Tomoko Miyakawa; Ryo Matsumura; Yuuki Yokota; Ikki Ishida; Junko Matsuo; Sumiko Yoshida; Miho Ota; Hiroshi Kunugi

  Translational psychiatry 10 (1) 161 - 161 2020/05
• Characterization of Postprandial Effects on CSF Metabolomics: A Pilot Study with Parallel Comparison to Plasma

  Kosuke Saito; Kotaro Hattori; Tomohiro Andou; Yoshinori Satomi; Masamitsu Gotou; Hiroyuki Kobayashi; Shinsuke Hidese; Hiroshi Kunugi

  Metabolites MDPI AG 10 (5) 185 - 185 2020/05
• Lauric acid promotes neuronal maturation mediated by astrocytes in primary cortical cultures.

  Shingo Nakajima; Hiroshi Kunugi

  Heliyon 6 (5) e03892  2020/05 [Refereed]
  
• Psychiatric Lecture 成因・危険因子 統合失調症の認知機能障害と介入

  功刀 浩

  精神科臨床legato / 「精神科臨床legato」編集委員会 編 メディカルレビュー社 6 (1) 18 - 21 2189-4388 2020/03
• Altered ethanolamine plasmalogen and phosphatidylethanolamine levels in blood plasma of patients with bipolar disorder.

  Shintaro Ogawa; Kotaro Hattori; Miho Ota; Shinsuke Hidese; Tomoko Miyakawa; Ryo Matsumura; Yuuki Yokota; Ikki Ishida; Junko Matsuo; Sumiko Yoshida; Yasuyo Yamazaki; Dayan Goodenowe; Hiroshi Kunugi

  Psychiatry and clinical neurosciences 74 (3) 204 - 210 2020/03
• Saturated fatty acid is a principal cause of anxiety-like behavior in diet-induced obese rats in relation to serum lysophosphatidyl choline level.

  Shingo Nakajima; Keiko Fukasawa; Mari Gotoh; Kimiko Murakami-Murofushi; Hiroshi Kunugi

  International journal of obesity (2005) 44 (3) 727 - 738 0307-0565 2020/03 [Refereed]
  
• The BDNF Val66Met polymorphism affects negative memory bias in civilian women with PTSD.

  Hiroaki Hori; Mariko Itoh; Fuyuko Yoshida; Mingming Lin; Madoka Niwa; Yuko Hakamata; Keiko Ino; Risa Imai; Sei Ogawa; Mie Matsui; Toshiko Kamo; Hiroshi Kunugi; Yoshiharu Kim

  Scientific reports 10 (1) 3151 - 3151 2020/02 [Refereed]
  
• Comparison of physiological and behavioral responses to chronic restraint stress between C57BL/6J and BALB/c mice.

  Shoko Tsuchimine; Hitomi Matsuno; Kazunori O'Hashi; Shuichi Chiba; Aya Yoshimura; Hiroshi Kunugi; Kazuhiro Sohya

  Biochemical and biophysical research communications 2020/02 [Refereed]
  
• 徹底分析シリーズ 最近の薬物療法-トレンドをざっくりアップデート 精神科領域における最近の薬物療法の動向-新薬･適応拡大･投与法の進歩

  功刀 浩

  LiSA 株式会社医学書院 27 (2) 166 - 170 1340-8836 2020/02
• 双極性障害におけるPUFAと炎症・FADS遺伝子・食生活との検討

  古賀 賀恵; 小倉 淳; 吉田 冬子; 服部 功太郎; 堀 弘明; 相澤 恵美子; 石田 一希; 功刀 浩

  日本病態栄養学会誌 (一社)日本病態栄養学会 23 (Suppl.) S - 129 1345-8167 2020/01
• Diet, nutrition, and women’s mental health

  KUNUGI Hiroshi

  Journal of Japanese Society of Psychosomatic Obstetrics and Gynecology Japanese Soiety of Psychosomatic Obstetrics and Gynecology 25 (2) 79 - 82 1345-2894 2020
• 食事・栄養学的側面からの女性のメンタルヘルス

  功刀 浩

  女性心身医学 一般社団法人 日本女性心身医学会 24 (3) 279 - 280 1345-2894 2020
• Correlation Between the Wechsler Adult Intelligence Scale- 3 rd Edition Metrics and Brain Structure in Healthy Individuals: A Whole-Brain Magnetic Resonance Imaging Study.

  Shinsuke Hidese; Miho Ota; Junko Matsuo; Ikki Ishida; Moeko Hiraishi; Yuuki Yokota; Kotaro Hattori; Yukihito Yomogida; Hiroshi Kunugi

  Frontiers in human neuroscience 14 211 - 211 2020
• Apitherapy for Parkinson's Disease: A Focus on the Effects of Propolis and Royal Jelly.

  Amira Mohammed Ali; Hiroshi Kunugi

  Oxidative medicine and cellular longevity 2020 1727142 - 1727142 2020
• Possible Long-Term Effects of Childhood Maltreatment on Cognitive Function in Adult Women With Posttraumatic Stress Disorder.

  Michi Nakayama; Hiroaki Hori; Mariko Itoh; Mingming Lin; Madoka Niwa; Keiko Ino; Risa Imai; Sei Ogawa; Atsushi Sekiguchi; Mie Matsui; Hiroshi Kunugi; Yoshiharu Kim

  Frontiers in psychiatry 11 344 - 344 2020 [Refereed]
  
• Proinflammatory status-stratified blood transcriptome profiling of civilian women with PTSD

  Hiroaki Hori; Fuyuko Yoshida; Mariko Itoh; Mingming Lin; Madoka Niwa; Keiko Ino; Risa Imai; Sei Ogawa; Mie Matsui; Toshiko Kamo; Hiroshi Kunugi; Yoshiharu Kim

  Psychoneuroendocrinology Elsevier BV 111 104491 - 104491 0306-4530 2020/01 [Refereed]
  
• Oleic acid is a potent inducer for lipid droplet accumulation through its esterification to glycerol by diacylglycerol acyltransferase in primary cortical astrocytes.

  Shingo Nakajima; Mari Gotoh; Keiko Fukasawa; Kimiko Murakami-Murofushi; Hiroshi Kunugi

  Brain research 1725 146484 - 146484 0006-8993 2019/12 [Refereed]
  
• Bee honey protects astrocytes against oxidative stress: A preliminary in vitro investigation.

  Amira Mohammed Ali; Hiroshi Kunugi

  Neuropsychopharmacology reports 39 (4) 312 - 314 2019/12
• Relationships of blood proinflammatory markers with psychological resilience and quality of life in civilian women with posttraumatic stress disorder.

  Risa Imai; Hiroaki Hori; Mariko Itoh; Mingming Lin; Madoka Niwa; Keiko Ino; Sei Ogawa; Atsushi Sekiguchi; Hiroshi Kunugi; Tatsuo Akechi; Toshiko Kamo; Yoshiharu Kim

  Scientific reports 9 (1) 17905 - 17905 2019/11 [Refereed]
  
• 臨床に役立つ基礎薬理学の用語解説(第1回) サイトカイン

  石渡 小百合; 功刀 浩

  臨床精神薬理 (株)星和書店 22 (11) 1102 - 1104 1343-3474 2019/11
• Structural brain network correlated with the resilience to traumatic events in the healthy participants: An MRI study on healthy people in a stricken area of the Great East Japan Earthquake.

  Miho Ota; Kiyotaka Nemoto; Ikki Ishida; Shinji Sato; Takashi Asada; Tetsuaki Arai; Hiroshi Kunugi

  Psychological trauma : theory, research, practice and policy 2019/10
• Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial.

  Shinsuke Hidese; Shintaro Ogawa; Miho Ota; Ikki Ishida; Zenta Yasukawa; Makoto Ozeki; Hiroshi Kunugi

  Nutrients 11 (10) 2019/10 [Refereed]
  
• 日本人統合失調症患者でのクロザピンと活性代謝物ノルクロザピンの血中濃度および血中濃度比の推移モデルの構築

  森田 和弥; 赤嶺 由美子; 三國 雅彦; 黒木 俊秀; 功刀 浩; 鬼木 健太郎; 猿渡 淳二; 古郡 規雄; 治療抵抗性統合失調症に対する治療戦略のためのデータベース構築に関する研究班

  日本臨床精神神経薬理学会・日本神経精神薬理学会合同年会プログラム・抄録集 日本臨床精神神経薬理学会・日本神経精神薬理学会 29回・49回 132 - 132 2019/10
• Royal Jelly and Its Components Promote Healthy Aging and Longevity: From Animal Models to Humans.

  Hiroshi Kunugi; Amira Mohammed Ali

  International journal of molecular sciences 20 (19) 2019/09
• Possible association between photic sneeze syndrome and migraine and psychological distress.

  Daimei Sasayama; Shinya Asano; Shun Nogawa; Shoko Takahashi; Kenji Saito; Hiroshi Kunugi

  Neuropsychopharmacology reports 39 (3) 217 - 222 2019/09
• Altered polyunsaturated fatty acid levels in relation to proinflammatory cytokines, fatty acid desaturase genotype, and diet in bipolar disorder.

  Koga N; Ogura J; Yoshida F; Hattori K; Hori H; Aizawa E; Ishida I; Kunugi H

  Translational psychiatry 9 (1) 208 - 208 2019/08 [Refereed]
  
• 【精神科診療マニュアル】気分障害 栄養・運動・その他の治療法

  石渡 小百合; 功刀 浩

  精神科 (有)科学評論社 35 (Suppl.1) 127 - 132 1347-4790 2019/07
• Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect.

  Masashi Ikeda; Atsushi Takahashi; Yoichiro Kamatani; Yukihide Momozawa; Takeo Saito; Kenji Kondo; Ayu Shimasaki; Kohei Kawase; Takaya Sakusabe; Yoshimi Iwayama; Tomoko Toyota; Tomoyasu Wakuda; Mitsuru Kikuchi; Nobuhisa Kanahara; Hidenaga Yamamori; Yuka Yasuda; Yuichiro Watanabe; Satoshi Hoya; Branko Aleksic; Itaru Kushima; Heii Arai; Manabu Takaki; Kotaro Hattori; Hiroshi Kunugi; Yuko Okahisa; Tohru Ohnuma; Norio Ozaki; Toshiyuki Someya; Ryota Hashimoto; Takeo Yoshikawa; Michiaki Kubo; Nakao Iwata

  Schizophrenia bulletin 45 (4) 824 - 834 0586-7614 2019/06 [Refereed]
  
• Construction of the common cortical space by spontaneous activity and its application in the mouse cortex.

  Kazunori O'Hashi; Kazuhiro Sohya; Hitomi Matsuno; Shoko Tsuchimine; Hiroshi Kunugi

  Biochemical and biophysical research communications 513 (4) 869 - 874 0006-291X 2019/06 [Refereed]
  
• Effects of Chronic L-theanine on Stress-related Symptoms and Cognitive Function in a Non-clinical Population: A Randomized Controlled Trial (P06-106-19)

  Hiroshi Kunugi; Shinsuke Hidese; Shintaro Ogawa; Miho Ota; Zenta Yasukawa; Makoto Ozeki

  Current Developments in Nutrition Oxford University Press (OUP) 3 (Supplement_1) 2019/06
• A Web-based Survey for the Association Between Food Allergy and Depression/psychological Distress in 11,876 Japanese (P18-019-19)

  Shinsuke Hidese; Shun Nogawa; Kenji Saito; Hiroshi Kunugi

  Current Developments in Nutrition Oxford University Press (OUP) 3 (Supplement_1) 2019/06
• An Open-label Clinical Study of Chronic L-theanine Supplementation in Patients with Major Depressive Disorder (P12-007-19)

  Shinsuke Hidese; Miho Ota; Hayato Ozawa; Tsutomu Okubo; Hiroshi Kunugi

  Current Developments in Nutrition Oxford University Press (OUP) 3 (Supplement_1) 2019/06
• A polymorphism of the methylenetetrahydrofolate reductase gene confers susceptibility to schizophrenia and related brain changes.

  Ota M; Sato N; Yoshida F; Hattori K; Hidese S; Teraishi T; Kunugi H

  Schizophrenia research Elsevier BV 208 462 - 464 0920-9964 2019/06 [Refereed]
  
• Cerebrospinal fluid BDNF pro-peptide levels in major depressive disorder and schizophrenia.

  Mizui T; Hattori K; Ishiwata S; Hidese S; Yoshida S; Kunugi H; Kojima M

  Journal of psychiatric research Elsevier BV 113 190 - 198 0022-3956 2019/06 [Refereed]
  
• The use of diffusional kurtosis imaging and neurite orientation dispersion and density imaging of the brain in bipolar disorder.

  Ota M; Noda T; Sato N; Hidese S; Teraishi T; Setoyama S; Matsuda H; Kunugi H

  Journal of affective disorders Elsevier BV 251 231 - 234 0165-0327 2019/05 [Refereed]
  
• Lysophosphatidic acid levels in cerebrospinal fluid and plasma samples in patients with major depressive disorder.

  Leo Gotoh; Misa Yamada; Kotaro Hattori; Daimei Sasayama; Takamasa Noda; Sumiko Yoshida; Hiroshi Kunugi; Mitsuhiko Yamada

  Heliyon 5 (5) e01699  2019/05 [Refereed]
  
• Reduced Serum and Cerebrospinal Fluid Levels of Autotaxin in Major Depressive Disorder.

  Kei Itagaki; Minoru Takebayashi; Hiromi Abe; Chiyo Shibasaki; Naoto Kajitani; Mami Okada-Tsuchioka; Kotaro Hattori; Sumiko Yoshida; Hiroshi Kunugi; Shigeto Yamawaki

  The international journal of neuropsychopharmacology 22 (4) 261 - 269 1461-1457 2019/04 [Refereed]
  
• Evidence for reduced homovanillic acid (HVA) in the cerebrospinal fluid of patients with depression.

  Ogawa S; Kunugi H

  Journal of affective disorders 255 0165-0327 2019/04 [Refereed]
  
• Association between lower estimated premorbid intelligence quotient and smoking behavior in patients with schizophrenia.

  Hidese S; Matsuo J; Ishida I; Hiraishi M; Teraishi T; Ota M; Hattori K; Kunugi H

  Schizophrenia research. Cognition Elsevier BV 15 7 - 13 2215-0013 2019/03 [Refereed]
  
• Levels of lysophosphatidic acid in cerebrospinal fluid and plasma of patients with schizophrenia.

  Leo Gotoh; Misa Yamada; Kotaro Hattori; Daimei Sasayama; Takamasa Noda; Sumiko Yoshida; Hiroshi Kunugi; Mitsuhiko Yamada

  Psychiatry research 273 331 - 335 0165-1781 2019/03 [Refereed]
  
• Food allergy is associated with depression and psychological distress: A web-based study in 11,876 Japanese.

  Hidese S; Nogawa S; Saito K; Kunugi H

  Journal of affective disorders Elsevier BV 245 213 - 218 0165-0327 2019/02 [Refereed]
  
• Effects of a medium-chain triglyceride-based ketogenic formula on cognitive function in patients with mild-to-moderate Alzheimer's disease.

  Miho Ota; Junko Matsuo; Ikki Ishida; Harumasa Takano; Yuma Yokoi; Hiroaki Hori; Sumiko Yoshida; Kinya Ashida; Kentaro Nakamura; Takeshi Takahashi; Hiroshi Kunugi

  Neuroscience letters 690 232 - 236 0304-3940 2019/01 [Refereed]
  
• Distinctive Neuroanatomical Substrates for Depression in Bipolar Disorder versus Major Depressive Disorder

  Koji Matsuo; Kenichiro Harada; Yusuke Fujita; Yasumasa Okamoto; Miho Ota; Hisashi Narita; Benson Mwangi; Carlos A. Gutierrez; Go Okada; Masahiro Takamura; Hirotaka Yamagata; Ichiro Kusumi; Hiroshi Kunugi; Takeshi Inoue; Jair C. Soares; Shigeto Yamawaki; Yoshifumi Watanabe

  Cerebral Cortex 29 (1) 202 - 214 1047-3211 2019 [Refereed]
  
• Trait Loci Mapping and CSF Proteome.

  Daimei Sasayama; Kotaro Hattori; Hiroshi Kunugi

  Methods in molecular biology (Clifton, N.J.) 2044 365 - 376 2019
• Reduced plasma orexin-A levels in patients with bipolar disorder.

  Shoko Tsuchimine; Kotaro Hattori; Miho Ota; Shinsuke Hidese; Toshiya Teraishi; Daimei Sasayama; Hiroaki Hori; Takamasa Noda; Sumiko Yoshida; Fuyuko Yoshida; Hiroshi Kunugi

  Neuropsychiatric disease and treatment 15 2221 - 2230 1176-6328 2019 [Refereed]
  
• The relationship between the Wechsler Memory Scale-Revised scores and whole-brain structure in patients with schizophrenia and healthy individuals.

  Hidese S; Ota M; Hori H; Matsuo J; Ishida I; Hiraishi M; Teraishi T; Hattori K; Kunugi H

  Cognitive neuropsychiatry Informa UK Limited 24 (1) 80 - 91 1354-6805 2019/01 [Refereed]
  
• Changes of Myelin Organization in Patients with Alzheimer's Disease Shown by q-Space Myelin Map Imaging.

  Ota M; Sato N; Kimura Y; Shigemoto Y; Kunugi H; Matsuda H

  Dementia and geriatric cognitive disorders extra 9 (1) 24 - 33 2019/01 [Refereed]
  
• Cerebrospinal fluid monoamine metabolite concentrations in depressive disorder: A meta-analysis of historic evidence.

  Shintaro Ogawa; Shoko Tsuchimine; Hiroshi Kunugi

  Journal of psychiatric research 105 137 - 146 0022-3956 2018/10 [Refereed]
  
• Involvement of IL-6 and GSK3β in impaired sensorimotor gating induced by high-fat diet.

  Wakabayashi C; Kunugi H

  Neuroscience research 147 33 - 38 0168-0102 2018/10 [Refereed]
  
• Basic fibroblast growth factor increased glucocorticoid receptors in cortical neurons through MAP kinase pathway.

  Tadahiro Numakawa; Haruki Odaka; Naoki Adachi; Shuichi Chiba; Yoshiko Ooshima; Hitomi Matsuno; Shingo Nakajima; Aya Yoshimura; Kazuhiro Fumimoto; Yohei Hirai; Hiroshi Kunugi

  Neurochemistry international 118 217 - 224 0197-0186 2018/09 [Refereed]
  
• Integrated profiling of phenotype and blood transcriptome for stress vulnerability and depression.

  Hori H; Nakamura S; Yoshida F; Teraishi T; Sasayama D; Ota M; Hattori K; Kim Y; Higuchi T; Kunugi H

  Journal of psychiatric research 104 202 - 210 0022-3956 2018/09 [Refereed]
  
• Relationship between Autistic Spectrum Trait and Regional Cerebral Blood Flow in Healthy Male Subjects.

  Ota M; Matsuo J; Sato N; Teraishi T; Hori H; Hattori K; Kamio Y; Maikusa N; Matsuda H; Kunugi H

  Psychiatry investigation 15 (10) 956 - 961 1738-3684 2018/09 [Refereed]
  
• Cognitive function in Japanese women with posttraumatic stress disorder: Association with exercise habits.

  Ryoko Narita-Ohtaki; Hiroaki Hori; Mariko Itoh; Mingming Lin; Madoka Niwa; Keiko Ino; Risa Imai; Sei Ogawa; Atsushi Sekiguchi; Mie Matsui; Hiroshi Kunugi; Toshiko Kamo; Yoshiharu Kim

  Journal of affective disorders 236 306 - 312 0165-0327 2018/08 [Refereed]
  
• Association of depression with body mass index classification, metabolic disease, and lifestyle: A web-based survey involving 11,876 Japanese people

  Shinsuke Hidese; Shinya Asano; Kenji Saito; Daimei Sasayama; Hiroshi Kunugi

  Journal of Psychiatric Research Elsevier Ltd 102 23 - 28 1879-1379 2018/07 [Refereed]
  
• Association between iron-deficiency anemia and depression: A web-based Japanese investigation.

  Hidese S; Saito K; Asano S; Kunugi H

  Psychiatry and clinical neurosciences Wiley 72 (7) 513 - 521 1323-1316 2018/07 [Refereed]
  
• Inflammatory markers and their possible effects on cognitive function in women with posttraumatic stress disorder.

  Risa Imai; Hiroaki Hori; Mariko Itoh; Mingming Lin; Madoka Niwa; Keiko Ino; Sei Ogawa; Makiko Ishida; Atsushi Sekiguchi; Mie Matsui; Hiroshi Kunugi; Tatsuo Akechi; Toshiko Kamo; Yoshiharu Kim

  Journal of psychiatric research 102 192 - 200 0022-3956 2018/07 [Refereed]
  
• Manual dexterity and brain structure in patients with schizophrenia: A whole-brain magnetic resonance imaging study

  Shinsuke Hidese; Miho Ota; Daimei Sasayama; Junko Matsuo; Ikki Ishida; Moeko Hiraishi; Toshiya Teraishi; Kotaro Hattori; Hiroshi Kunugi

  Psychiatry Research - Neuroimaging Elsevier Ireland Ltd 276 9 - 14 1872-7506 2018/06 [Refereed]
  
• A genome-wide association study on photic sneeze syndrome in a Japanese population

  Daimei Sasayama; Shinya Asano; Shun Nogawa; Shoko Takahashi; Kenji Saito; Hiroshi Kunugi

  Journal of Human Genetics Nature Publishing Group 63 (6) 765 - 768 1435-232X 2018/06 [Refereed]
  
• A Single Intraperitoneal Injection of Endotoxin Changes Glial Cells in Rats as Revealed by Positron Emission Tomography Using [11C]PK11195.

  Miho Ota; Jun Ogura; Shintaro Ogawa; Koichi Kato; Hiroshi Matsuda; Hiroshi Kunugi

  Nuclear medicine and molecular imaging 52 (3) 224 - 228 1869-3474 2018/06 [Refereed]
  
• ストレス脆弱性についての表現型と末梢血トランスクリプトームの統合解析

  堀 弘明; 中村 誠二; 吉田 冬子; 寺石 俊也; 篠山 大明; 太田 深秀; 服部 功太郎; 金 吉晴; 樋口 輝彦; 功刀 浩

  臨床薬理の進歩 (公財)臨床薬理研究振興財団 (39) 140 - 152 0914-4366 2018/06
• 中鎖脂肪酸を含むケトン食によるアルツハイマー病患者の認知機能改善効果の検討

  松尾 淳子; 太田 深秀; 石田 一希; 堀 弘明; 高野 晴成; 横井 優磨; 吉田 寿美子; 芦田 欣也; 中村 健太郎; 高橋 毅; 功刀 浩

  精神神経学雑誌 (公社)日本精神神経学会 (2018特別号) S385 - S385 0033-2658 2018/06 [Refereed]
  
• Low cocaine- and amphetamine-regulated transcript (CART) peptide levels in human cerebrospinal fluid of major depressive disorder (MDD) patients

  Hyung Shin Yoon; Kotaro Hattori; Daimei Sasayama; Hiroshi Kunugi

  Journal of Affective Disorders Elsevier B.V. 232 134 - 138 1573-2517 2018/05 [Refereed]
  
• 日本人統合失調症患者におけるクロザピン及び活性代謝物ノルクロザピンの母集団薬物動態解析

  森田 和弥; 鬼木 健太郎; 赤嶺 由美子; 三國 雅彦; 黒木 俊秀; 功刀 浩; 猿渡 淳二; 古郡 規雄

  TDM研究 (一社)日本TDM学会 35 (2) 149 - 149 0911-1026 2018/05
• Relationship of handgrip strength and body mass index with cognitive function in patients with schizophrenia

  Shinsuke Hidese; Junko Matsuo; Ikki Ishida; Moeko Hiraishi; Toshiya Teraishi; Miho Ota; Kotaro Hattori; Hiroshi Kunugi

  Frontiers in Psychiatry Frontiers Media S.A. 9 156  1664-0640 2018/04 [Refereed]
  
• Sensorimotor gating in depressed and euthymic patients with bipolar disorder: Analysis on prepulse inhibition of acoustic startle response stratified by gender and state

  Junko Matsuo; Miho Ota; Shinsuke Hidese; Toshiya Teraishi; Hiroaki Hori; Ikki Ishida; Moeko Hiraishi; Hiroshi Kunugi

  Frontiers in Psychiatry Frontiers Media S.A. 9 123  1664-0640 2018/04 [Refereed]
  
• 13C-phenylalanine breath test and serum biopterin in schizophrenia, bipolar disorder and major depressive disorder

  Toshiya Teraishi; Masahiro Kajiwara; Hiroaki Hori; Daimei Sasayama; Shinsuke Hidese; Junko Matsuo; Ikki Ishida; Yasuhiro Kajiwara; Yuji Ozeki; Miho Ota; Kotaro Hattori; Teruhiko Higuchi; Hiroshi Kunugi

  Journal of Psychiatric Research Elsevier Ltd 99 142 - 150 1879-1379 2018/04 [Refereed]
  
• Increased cerebrospinal fluid complement C5 levels in major depressive disorder and schizophrenia

  Takashi Ishii; Kotaro Hattori; Tomoko Miyakawa; Kentaro Watanabe; Shinsuke Hidese; Daimei Sasayama; Miho Ota; Toshiya Teraishi; Hiroaki Hori; Sumiko Yoshida; Akihiko Nunomura; Kazuyuki Nakagome; Hiroshi Kunugi

  Biochemical and Biophysical Research Communications Elsevier B.V. 497 (2) 683 - 688 1090-2104 2018/03 [Refereed]
  
• A genome-wide association study identifies two novel susceptibility loci and trans population polygenicity associated with bipolar disorder

  M. Ikeda; A. Takahashi; Y. Kamatani; Y. Okahisa; H. Kunugi; N. Mori; T. Sasaki; T. Ohmori; Y. Okamoto; H. Kawasaki; S. Shimodera; T. Kato; H. Yoneda; R. Yoshimura; M. Iyo; K. Matsuda; M. Akiyama; K. Ashikawa; K. Kashiwase; K. Tokunaga; K. Kondo; T. Saito; A. Shimasaki; K. Kawase; T. Kitajima; K. Matsuo; M. Itokawa; T. Someya; T. Inada; R. Hashimoto; T. Inoue; K. Akiyama; H. Tanii; H. Arai; S. Kanba; N. Ozaki; I. Kusumi; T. Yoshikawa; M. Kubo; N. Iwata; Advanced Collaborative Study of Mood Disorder (COSMO) team

  Molecular Psychiatry Nature Publishing Group 23 (3) 639 - 647 1476-5578 2018/03 [Refereed]
  
• The use of diffusional kurtosis imaging and neurite orientation dispersion and density imaging of the brain in major depressive disorder

  Miho Ota; Takamasa Noda; Noriko Sato; Shinsuke Hidese; Toshiya Teraishi; Shiori Setoyama; Daichi Sone; Hiroshi Matsuda; Hiroshi Kunugi

  Journal of Psychiatric Research Elsevier Ltd 98 22 - 29 1879-1379 2018/03 [Refereed]
  
• A genome-wide association study identifies two novel susceptibility loci and trans population polygenicity associated with bipolar disorder

  M. Ikeda; A. Takahashi; Y. Kamatani; Y. Okahisa; H. Kunugi; N. Mori; T. Sasaki; T. Ohmori; Y. Okamoto; H. Kawasaki; S. Shimodera; T. Kato; H. Yoneda; R. Yoshimura; M. Iyo; K. Matsuda; M. Akiyama; K. Ashikawa; K. Kashiwase; K. Tokunaga; K. Kondo; T. Saito; A. Shimasaki; K. Kawase; T. Kitajima; K. Matsuo; M. Itokawa; T. Someya; T. Inada; R. Hashimoto; T. Inoue; K. Akiyama; H. Tanii; H. Arai; S. Kanba; N. Ozaki; I. Kusumi; T. Yoshikawa; M. Kubo; N. Iwata; Advanced Collaborative Study of Mood Disorder (COSMO) team

  Molecular Psychiatry Nature Publishing Group 23 (3) 639 - 647 1476-5578 2018/03
• The effects of adjunctive intranasal oxytocin in patients with schizophrenia

  Miho Ota; Sumiko Yoshida; Masanori Nakata; Toshihiko Yada; Hiroshi Kunugi

  Postgraduate Medicine Taylor and Francis Inc. 130 (1) 122 - 128 1941-9260 2018/01 [Refereed]
  
• Association of obesity with cognitive function and brain structure in patients with major depressive disorder

  Shinsuke Hidese; Miho Ota; Junko Matsuo; Ikki Ishida; Moeko Hiraishi; Sumiko Yoshida; Takamasa Noda; Noriko Sato; Toshiya Teraishi; Kotaro Hattori; Hiroshi Kunugi

  JOURNAL OF AFFECTIVE DISORDERS ELSEVIER SCIENCE BV 225 188 - 194 0165-0327 2018/01 [Refereed]
  
• Plasma amino acid profile in major depressive disorder: Analyses in two independent case-control sample sets

  Shintaro Ogawa; Norie Koga; Kotaro Hattori; Junko Matsuo; Miho Ota; Hiroaki Hori; Daimei Sasayama; Toshiya Teraishi; Ikki Ishida; Fuyuko Yoshida; Sumiko Yoshida; Takamasa Noda; Teruhiko Higuchi; Hiroshi Kunugi

  Journal of Psychiatric Research Elsevier Ltd 96 23 - 32 1879-1379 2018/01 [Refereed]
  
• Effects of L-theanine on anxiety-like behavior, cerebrospinal fluid amino acid profile, and hippocampal activity in Wistar Kyoto rats.

  Shintaro Ogawa; Miho Ota; Jun Ogura; Koichi Kato; Hiroshi Kunugi

  Psychopharmacology 235 (1) 37 - 45 0033-3158 2018/01 [Refereed]
  
• Cerebrospinal fluid D-serine concentrations in major depressive disorder negatively correlate with depression severity

  Sayuri Ishiwata; Kotaro Hattori; Daimei Sasayama; Toshiya Teraishi; Tomoko Miyakawa; Yuuki Yokota; Ryo Matsumura; Toru Nishikawa; Hiroshi Kunugi

  JOURNAL OF AFFECTIVE DISORDERS ELSEVIER SCIENCE BV 226 155 - 162 0165-0327 2018/01 [Refereed]
  
• Rotigotine, a dopamine receptor agonist, increased BDNF protein levels in the rat cortex and hippocampus

  Naoki Adachi; Aya Yoshimura; Shuichi Chiba; Shintaro Ogawa; Hiroshi Kunugi

  Neuroscience Letters Elsevier Ireland Ltd 662 44 - 50 1872-7972 2018/01 [Refereed]
  
• Association of obesity with cognitive function and brain structure in patients with major depressive disorder

  Shinsuke Hidese; Miho Ota; Junko Matsuo; Ikki Ishida; Moeko Hiraishi; Sumiko Yoshida; Takamasa Noda; Noriko Sato; Toshiya Teraishi; Kotaro Hattori; Hiroshi Kunugi

  Journal of Affective Disorders Elsevier B.V. 236 314  0165-0327 2018/01 [Refereed]
  
• The Sox2 promoter-driven CD63-GFP transgenic rat model allows tracking of neural stem cell-derived extracellular vesicles

  Aya Yoshimura; Naoki Adachi; Hitomi Matsuno; Masaki Kawamata; Yusuke Yoshioka; Hisae Kikuchi; Haruki Odaka; Tadahiro Numakawa; Hiroshi Kunugi; Takahiro Ochiya; Yoshitaka Tamai

  DMM Disease Models and Mechanisms Company of Biologists Ltd 11 (1) 1754-8411 2018/01 [Refereed]
  
• Depressive Disorder, Autistic Spectrum Disorder and Gut Microbiota

  KUNUGI Hiroshi

  Journal of Intestinal Microbiology The Intestinal Microbiology Society 32 (1) 7 - 13 1343-0882 2018
• Bifidobacterium and Lactobacillus Counts in the Gut Microbiota of Patients With Bipolar Disorder and Healthy Controls.

  Aizawa E; Tsuji H; Asahara T; Takahashi T; Teraishi T; Yoshida S; Koga N; Hattori K; Ota M; Kunugi H

  Frontiers in psychiatry 9 730 - 730 2018 [Refereed]
  
• Correlation of reduced social communicational and interactional skills with regional grey matter volumes in schizophrenia patients

  Miho Ota; Junko Matsuo; Noriko Sato; Toshiya Teraishi; Hiroaki Hori; Kotaro Hattori; Yoko Kamio; Hiroshi Kunugi

  Acta Neuropsychiatrica Cambridge University Press 29 (6) 374 - 381 1601-5215 2017/12 [Refereed]
  
• Association between the scores of the Japanese version of the Brief Assessment of Cognition in Schizophrenia and whole-brain structure in patients with chronic schizophrenia: A voxel-based morphometry and diffusion tensor imaging study

  Shinsuke Hidese; Miho Ota; Junko Matsuo; Ikki Ishida; Moeko Hiraishi; Toshiya Teraishi; Kotaro Hattori; Hiroshi Kunugi

  PSYCHIATRY AND CLINICAL NEUROSCIENCES WILEY 71 (12) 826 - 835 1323-1316 2017/12 [Refereed]
  
• Alpha band event-related desynchronization underlying social situational context processing during irony comprehension: A magnetoencephalography source localization study

  Yoritaka Akimoto; Hidetoshi Takahashi; Atsuko Gunji; Yuu Kaneko; Michiko Asano; Junko Matsuo; Miho Ota; Hiroshi Kunugi; Takashi Hanakawa; Reiko Mazuka; Yoko Kamio

  BRAIN AND LANGUAGE ACADEMIC PRESS INC ELSEVIER SCIENCE 175 42 - 46 0093-934X 2017/12 [Refereed]
  
• Correlation of reduced social communicational and interactional skills with regional grey matter volumes in schizophrenia patients

  Miho Ota; Junko Matsuo; Noriko Sato; Toshiya Teraishi; Hiroaki Hori; Kotaro Hattori; Yoko Kamio; Hiroshi Kunugi

  ACTA NEUROPSYCHIATRICA CAMBRIDGE UNIV PRESS 29 (6) 374 - 381 1601-5215 2017/12 [Refereed]
  
• Different effects of rotigotine and ropinirole on cholinergic transmission in the mouse medial prefrontal cortex

  Kazuhiro Sohya; Kazunori O'Hashi; Hideki Toma; Hiroshi Kunugi

  Psychogeriatrics Blackwell Publishing Ltd 17 (6) 502 - 503 1479-8301 2017/11 [Refereed]
  
• Association of body mass index-related single nucleotide polymorphisms with psychiatric disease and memory performance in a Japanese population

  Midori Ninomiya-Baba; Junko Matsuo; Daimei Sasayama; Hiroaki Hori; Toshiya Teraishi; Miho Ota; Kotaro Hattori; Takamasa Noda; Ikki Ishida; Shigenobu Shibata; Hiroshi Kunugi

  Acta Neuropsychiatrica Cambridge University Press 29 (5) 299 - 308 1601-5215 2017/10 [Refereed]
  
• Whole brain analyses of age-related microstructural changes quantified using different diffusional magnetic resonance imaging methods

  Miho Ota; Noriko Sato; Norihide Maikusa; Daichi Sone; Hiroshi Matsuda; Hiroshi Kunugi

  JAPANESE JOURNAL OF RADIOLOGY SPRINGER 35 (10) 584 - 589 1867-1071 2017/10 [Refereed]
  
• Relationships of Cerebrospinal Fluid Monoamine Metabolite Levels With Clinical Variables in Major Depressive Disorder

  Hyung Shin Yoon; Kotaro Hattori; Shintaro Ogawa; Daimei Sasayama; Miho Ota; Toshiya Teraishi; Hiroshi Kunugi

  JOURNAL OF CLINICAL PSYCHIATRY PHYSICIANS POSTGRADUATE PRESS 78 (8) E947 - + 0160-6689 2017/09 [Refereed]
  
• うつ病を検出可能な血液遺伝子発現バイオマーカーの同定

  中村 誠二; 堀 弘明; 石澤 洋平; 松原 謙一; 的場 亮; 功刀 浩

  日本生物学的精神医学会・日本神経精神薬理学会合同年会プログラム・抄録集 日本生物学的精神医学会・日本神経精神薬理学会 39回・47回 191 - 191 2017/09
• 統合失調症における社会認知機能と大脳皮質形態についての検討(Correlation of reduced social communicational and interactional skills with regional gray matter volumes in schizophrenia patients)

  太田 深秀; 松尾 淳子; 寺石 俊也; 堀 弘明; 服部 功太郎; 神尾 陽子; 功刀 浩

  日本生物学的精神医学会・日本神経精神薬理学会合同年会プログラム・抄録集 日本生物学的精神医学会・日本神経精神薬理学会 39回・47回 196 - 196 2017/09
• 精神疾患の脳脊髄液における補体C5の亢進

  石井 敬; 服部 功太郎; 宮川 友子; 篠山 大明; 秀瀬 真輔; 太田 深秀; 横田 悠季; 松村 亮; 野田 隆政; 吉田 寿美子; 後藤 雄一; 功刀 浩

  日本生物学的精神医学会・日本神経精神薬理学会合同年会プログラム・抄録集 日本生物学的精神医学会・日本神経精神薬理学会 39回・47回 169 - 169 2017/09
• 脳脊髄液中D-セリン濃度とうつ病重症度の関連

  石渡 小百合; 服部 功太郎; 篠山 大明; 寺石 俊也; 宮川 友子; 横田 悠季; 松村 亮; 西川 徹; 功刀 浩

  日本生物学的精神医学会・日本神経精神薬理学会合同年会プログラム・抄録集 日本生物学的精神医学会・日本神経精神薬理学会 39回・47回 170 - 170 2017/09
• Wistar Kyotoラットにおける不安様行動・脳脊髄液中アミノ酸組成・海馬代謝活動へのL-テアニンの効果

  小川 眞太朗; 太田 深秀; 小倉 淳; 加藤 孝一; 功刀 浩

  日本生物学的精神医学会・日本神経精神薬理学会合同年会プログラム・抄録集 日本生物学的精神医学会・日本神経精神薬理学会 39回・47回 199 - 199 2017/09 [Refereed]
  
• Enrichment of deleterious variants of mitochondrial DNA polymerase gene (POLG1) in bipolar disorder

  Takaoki Kasahara; Mizuho Ishiwata; Chihiro Kakiuchi; Satoshi Fuke; Nakao Iwata; Norio Ozaki; Hiroshi Kunugi; Yoshio Minabe; Kazuhiko Nakamura; Yasuhide Iwata; Kumiko Fujii; Shigenobu Kanba; Hiroshi Ujike; Ichiro Kusumi; Muneko Kataoka; Nana Matoba; Atsushi Takata; Kazuya Iwamoto; Takeo Yoshikawa; Tadafumi Kato

  PSYCHIATRY AND CLINICAL NEUROSCIENCES WILEY 71 (8) 518 - 529 1323-1316 2017/08 [Refereed]
  
• A personality-based latent class typology of outpatients with major depressive disorder: association with symptomatology, prescription pattern and social function

  Hiroaki Hori; Toshiya Teraishi; Anna Nagashima; Norie Koga; Miho Ota; Kotaro Hattori; Yoshiharu Kim; Teruhiko Higuchi; Hiroshi Kunugi

  JOURNAL OF AFFECTIVE DISORDERS ELSEVIER SCIENCE BV 217 8 - 15 0165-0327 2017/08 [Refereed]
  
• Plasma and cerebrospinal fluid G72 protein levels in schizophrenia and major depressive disorder

  Sayuri Ishiwata; Kotaro Hattori; Daimei Sasayama; Toshiya Teraishi; Tomoko Miyakawa; Yuuki Yokota; Ryo Matsumura; Fuyuko Yoshida; Tom Nishikawa; Hiroshi Kunugi

  PSYCHIATRY RESEARCH ELSEVIER IRELAND LTD 254 244 - 250 0165-1781 2017/08 [Refereed]
  
• Cerebrospinal fluid neural cell adhesion molecule levels and their correlation with clinical variables in patients with schizophrenia, bipolar disorder, and major depressive disorder

  Shinsuke Hidese; Kotaro Hattori; Daimei Sasayama; Tomoko Miyakawa; Ryo Matsumura; Yuuki Yokota; Ikki Ishida; Junko Matsuo; Takamasa Noda; Sumiko Yoshida; Toshiya Teraishi; Hiroaki Hori; Miho Ota; Hiroshi Kunugi

  PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY PERGAMON-ELSEVIER SCIENCE LTD 76 12 - 18 0278-5846 2017/06 [Refereed]
  
• 双極性障害における多価不飽和脂肪酸濃度の検討

  古賀 賀恵; 服部 功太郎; 堀 弘明; 太田 深秀; 秀瀬 真輔; 相澤 恵美子; 功刀 浩

  精神神経学雑誌 (公社)日本精神神経学会 (2017特別号) S345 - S345 0033-2658 2017/06
• 大うつ病性障害における感覚フィルター機能の減弱

  松尾 淳子; 太田 深秀; 秀瀬 真輔; 堀 弘明; 寺石 俊也; 功刀 浩

  精神神経学雑誌 (公社)日本精神神経学会 (2017特別号) S348 - S348 0033-2658 2017/06
• 統合失調症およびうつ病患者における血漿・脳脊髄液中G72タンパク量の変化

  石渡 小百合; 服部 功太郎; 篠山 大明; 寺石 俊也; 宮川 友子; 横田 悠季; 松村 亮; 西川 徹; 功刀 浩

  日本神経精神薬理学雑誌 (一社)日本神経精神薬理学会 37 (3) 101 - 102 1340-2544 2017/06
• Metabolic profile alterations in the postmortem brains of patients with schizophrenia using capillary electrophoresis-mass spectrometry

  Takashi Fujii; Kotaro Hattori; Tomoko Miyakawa; Yoshiaki Ohashi; Hajime Sato; Hiroshi Kunugi

  SCHIZOPHRENIA RESEARCH ELSEVIER SCIENCE BV 183 70 - 74 0920-9964 2017/05 [Refereed]
  
• Effects of chronic l-theanine administration in patients with major depressive disorder: An open-label study

  Shinsuke Hidese; Miho Ota; Chisato Wakabayashi; Takamasa Noda; Hayato Ozawa; Tsutomu Okubo; Hiroshi Kunugi

  Acta Neuropsychiatrica Cambridge University Press 29 (2) 72 - 79 1601-5215 2017/04 [Refereed]
  
• Brain structure differences among male schizophrenic patients with history of serious violent acts: an MRI voxel-based morphometric study (vol 17, pg 105, 2017)

  Noriomi Kuroki; Hiroko Kashiwagi; Miho Ota; Masanori Ishikawa; Hiroshi Kunugi; Noriko Sato; Naotsugu Hirabayashi; Toshio Ota

  BMC PSYCHIATRY BIOMED CENTRAL LTD 17 (1) 105  1471-244X 2017/04 [Refereed]
  
• Brain structure differences among male schizophrenic patients with history of serious violent acts: an MRI voxel-based morphometric study (vol 17, pg 105, 2017)

  Noriomi Kuroki; Hiroko Kashiwagi; Miho Ota; Masanori Ishikawa; Hiroshi Kunugi; Noriko Sato; Naotsugu Hirabayashi; Toshio Ota

  BMC PSYCHIATRY BIOMED CENTRAL LTD 17 (1) 136  1471-244X 2017/04 [Refereed]
  
• (-)-Linalool influence on the cerebral blood flow in healthy male volunteers revealed by three-dimensional pseudo-continuous arterial spin labeling

  Miho Ota; Noriko Sato; Daichi Sone; Jun Ogura; Hiroshi Kunugi

  INDIAN JOURNAL OF PSYCHIATRY MEDKNOW PUBLICATIONS & MEDIA PVT LTD 59 (2) 225 - 227 0019-5545 2017/04 [Refereed]
  
• Effects of chronic l-theanine administration in patients with major depressive disorder: an open-label study

  Shinsuke Hidese; Miho Ota; Chisato Wakabayashi; Takamasa Noda; Hayato Ozawa; Tsutomu Okubo; Hiroshi Kunugi

  ACTA NEUROPSYCHIATRICA CAMBRIDGE UNIV PRESS 29 (2) 72 - 79 1601-5215 2017/04 [Refereed]
  
• Correlation of reduced social communicational and interactional skills with regional grey matter volumes in schizophrenia patients.

  Ohta M; Matsuo J; Sato N; Teraishi T; Hori H; Hattori K; Kamio Y; Kunugi H

  Acta Neuropsychiatr. 10 1 - 8 2017/04 [Refereed]
  
• Sexually dimorphic deficits of prepulse inhibition in patients with major depressive disorder and their relationship to symptoms: A large single ethnicity study

  Junko Matsuo; Miho Ota; Shinsuke Hidese; Hiroaki Hori; Toshiya Teraishi; Ikki Ishida; Moeko Hiraishi; Hiroshi Kunugi

  JOURNAL OF AFFECTIVE DISORDERS ELSEVIER SCIENCE BV 211 75 - 82 0165-0327 2017/03 [Refereed]
  
• Structural differences in hippocampal subfields among schizophrenia patients, major depressive disorder patients, and healthy subjects

  Miho Ota; Noriko Sato; Shinsuke Hidese; Toshiya Teraishi; Norihide Maikusa; Hiroshi Matsuda; Kotaro Hattori; Hiroshi Kunugi

  PSYCHIATRY RESEARCH-NEUROIMAGING ELSEVIER IRELAND LTD 259 54 - 59 0925-4927 2017/01 [Refereed]
  
• Genome-wide quantitative trait loci mapping of the human cerebrospinal fluid proteome

  Daimei Sasayama; Kotaro Hattori; Shintaro Ogawa; Yuuki Yokota; Ryo Matsumura; Toshiya Teraishi; Hiroaki Hori; Miho Ota; Sumiko Yoshida; Hiroshi Kunugi

  HUMAN MOLECULAR GENETICS OXFORD UNIV PRESS 26 (1) 44 - 51 0964-6906 2017/01 [Refereed]
  
• Re-evaluation of soluble APP-α and APP-β in cerebrospinal fluid as potential biomarkers for early diagnosis of dementia disorders.

  Wataru Araki; Kotaro Hattori; Kazutomi Kanemaru; Yuma Yokoi; Yoshie Omachi; Harumasa Takano; Masuhiro Sakata; Sumiko Yoshida; Tadashi Tsukamoto; Miho Murata; Yuko Saito; Hiroshi Kunugi; Yu-Ichi Goto; Utako Nagaoka; Masahiro Nagao; Takashi Komori; Kunimasa Arima; Kenji Ishii; Shigeo Murayama; Hiroshi Matsuda; Hisateru Tachimori; Yumiko M Araki; Hidehiro Mizusawa

  Biomarker research 5 28 - 28 2017 [Refereed]
  
• Chronic glucocorticoid exposure suppressed the differentiation and survival of embryonic neural stem/progenitor cells: Possible involvement of ERK and PI3K/Akt signaling in the neuronal differentiation

  Haruki Odaka; Tadahiro Numakawa; Aya Yoshimura; Shingo Nakajima; Naoki Adachi; Yoshiko Ooshima; Takafumi Inoue; Hiroshi Kunugi

  NEUROSCIENCE RESEARCH ELSEVIER IRELAND LTD 113 28 - 36 0168-0102 2016/12 [Refereed]
  
• Plasma Metabolites Predict Severity of Depression and Suicidal Ideation in Psychiatric Patients-A Multicenter Pilot Analysis

  Daiki Setoyama; Takahiro A. Kato; Ryota Hashimoto; Hiroshi Kunugi; Kotaro Hattori; Kohei Hayakawa; Mina Sato-Kasai; Norihiro Shimokawa; Sachie Kaneko; Sumiko Yoshida; Yu-ichi Goto; Yuka Yasuda; Hidenaga Yamamori; Masahiro Ohgidani; Noriaki Sagata; Daisuke Miura; Dongchon Kang; Shigenobu Kanba

  PLOS ONE PUBLIC LIBRARY SCIENCE 11 (12) e0165267  1932-6203 2016/12 [Refereed]
  
• Effects of ankyrin 3 gene risk variants on brain structures in patients with bipolar disorder and healthy subjects

  Miho Ota; Hiroaki Hori; Noriko Sato; Fuyuko Yoshida; Kotaro Hattori; Toshiya Teraishi; Hiroshi Kunugi

  PSYCHIATRY AND CLINICAL NEUROSCIENCES WILEY-BLACKWELL 70 (11) 498 - 506 1323-1316 2016/11 [Refereed]
  
• A large single ethnicity study of prepulse inhibition in schizophrenia: Separate analysis by sex focusing on effect of symptoms

  Junko Matsuo; Miho Ota; Hiroaki Hori; Shinsuke Hidese; Toshiya Teraishi; Ikki Ishida; Moeko Hiraishi; Hiroshi Kunugi

  JOURNAL OF PSYCHIATRIC RESEARCH PERGAMON-ELSEVIER SCIENCE LTD 82 155 - 162 0022-3956 2016/11 [Refereed]
  
• Effect of a ketogenic meal on cognitive function in elderly adults: potential for cognitive enhancement

  Miho Ota; Junko Matsuo; Ikki Ishida; Kotaro Hattori; Toshiya Teraishi; Hidekazu Tonouchi; Kinya Ashida; Takeshi Takahashi; Hiroshi Kunugi

  PSYCHOPHARMACOLOGY SPRINGER 233 (21-22) 3797 - 3802 0033-3158 2016/10 [Refereed]
  
• Possible association of Bifidobacterium and Lactobacillus in the gut microbiota of patients with major depressive disorder

  Emiko Aizawa; Hirokazu Tsuji; Takashi Asahara; Takuya Takahashi; Toshiya Teraishi; Sumiko Yoshida; Miho Ota; Norie Koga; Kotaro Hattori; Hiroshi Kunugi

  JOURNAL OF AFFECTIVE DISORDERS ELSEVIER SCIENCE BV 202 254 - 257 0165-0327 2016/09 [Refereed]
  
• Generation of a novel transgenic rat model for tracing extracellular vesicles in body fluids

  Aya Yoshimura; Masaki Kawamata; Yusuke Yoshioka; Takeshi Katsuda; Hisae Kikuchi; Yoshitaka Nagai; Naoki Adachi; Tadahiro Numakawa; Hiroshi Kunugi; Takahiro Ochiya; Yoshitaka Tamai

  SCIENTIFIC REPORTS NATURE PUBLISHING GROUP 6 31172  2045-2322 2016/08 [Refereed]
  
• Negative regulation of microRNA-132 in expression of synaptic proteins in neuronal differentiation of embryonic neural stem cells

  Aya Yoshimura; Tadahiro Numakawa; Haruki Odaka; Naoki Adachi; Yoshitaka Tamai; Hiroshi Kunugi

  NEUROCHEMISTRY INTERNATIONAL PERGAMON-ELSEVIER SCIENCE LTD 97 26 - 33 0197-0186 2016/07 [Refereed]
  
• 大うつ病性障害における血漿中アミノ酸濃度の変化

  小川 眞太朗; 服部 功太郎; 古賀 賀恵; 篠山 大明; 太田 深秀; 堀 弘明; 寺石 俊也; 吉田 寿美子; 野田 隆政; 樋口 輝彦; 功刀 浩

  日本神経精神薬理学会年会プログラム・抄録集 (一社)日本神経精神薬理学会 46回 214 - 214 2016/07
• 24-h activity rhythm and sleep in depressed outpatients

  Hiroaki Hori; Node Koga; Shinsuke Hidese; Anna Nagashima; Yoshiharu Kim; Teruhiko Higuchi; Hiroshi Kunugi

  JOURNAL OF PSYCHIATRIC RESEARCH PERGAMON-ELSEVIER SCIENCE LTD 77 27 - 34 0022-3956 2016/06 [Refereed]
  
• Depressive disorder and gut-brain interaction

  Hiroshi Kunugi

  Brain and Nerve Igaku-Shoin Ltd 68 (6) 641 - 646 1881-6096 2016/06 [Refereed]
  
• 統合失調症患者における聴覚性驚愕反応のプレパルス抑制障害

  松尾 淳子; 太田 深秀; 寺石 俊也; 堀 弘明; 功刀 浩

  精神神経学雑誌 (公社)日本精神神経学会 (2016特別号) S359 - S359 0033-2658 2016/06
• 東日本大震災の「隠れた被災地」茨城県における精神的影響について 震災1年後と3年後の検討

  佐藤 晋爾; 服部 功太郎; 太田 深秀; 内田 和彦; 石田 一希; 功刀 浩; 朝田 隆

  精神神経学雑誌 (公社)日本精神神経学会 (2016特別号) S475 - S475 0033-2658 2016/06
• Distinct and shared morphometric biomarkers of depressed individuals with bipolar disorder and major depressive disorder

  Matsuo Koji; Fujita Yusuke; Harada Kenichiro; Inoue Takeshi; Kunugi Hiroshi; Kusumi Ichiro; Narita Hisashi; Okada Go; Okamoto Yasumasa; Ota Miho; Takamura Masahiro; Watanabe Yoshifumi; Yamagata Hirotaka; Yamawaki Shigeto

  INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY 19 62 - 63 1461-1457 2016/06 [Refereed]
  
• THE NEUROPROTECTIVE EFFECTS AND POSSIBLE MECHANISM OF ACTION OF A METHANOL EXTRACT FROM ASPARAGUS COCHINCHINENSIS: IN VITRO AND IN VIVO STUDIES

  A. Jalsrai; T. Numakawa; H. Kunugi; D. C. Dieterich; A. Becker

  NEUROSCIENCE PERGAMON-ELSEVIER SCIENCE LTD 322 452 - 463 0306-4522 2016/05 [Refereed]
  
• Psychiatric Lecture 成因・危険因子 うつ病リスク因子としての食生活・栄養

  功刀 浩

  精神科臨床legato / 「精神科臨床legato」編集委員会 編 メディカルレビュー社 2 (2) 72 - 77 2189-4388 2016/04
• The inactivation of extracellular signal-regulated kinase by glucagon-like peptide-1 contributes to neuroprotection against oxidative stress

  Shingo Nakajima; Tadahiro Numakawa; Naoki Adachi; Hyung Shin Yoon; Haruki Odaka; Yoshiko Ooshima; Hiroshi Kunugi

  NEUROSCIENCE LETTERS ELSEVIER IRELAND LTD 616 105 - 110 0304-3940 2016/03 [Refereed]
  
• Blood-based gene expression signatures of medication-free outpatients with major depressive disorder: integrative genome-wide and candidate gene analyses

  Hiroaki Hori; Daimei Sasayama; Toshiya Teraishi; Noriko Yamamoto; Seiji Nakamura; Miho Ota; Kotaro Hattori; Yoshiharu Kim; Teruhiko Higuchi; Hiroshi Kunugi

  SCIENTIFIC REPORTS NATURE PUBLISHING GROUP 6 18776  2045-2322 2016/01 [Refereed]
  
• Striatal and extrastriatal dopamine release in the common marmoset brain measured by positron emission tomography and [F-18]fallypride

  Miho Ota; Shintaro Ogawa; Koichi Kato; Chiaki Masuda; Hiroshi Kunugi

  NEUROSCIENCE RESEARCH ELSEVIER IRELAND LTD 101 1 - 5 0168-0102 2015/12 [Refereed]
  
• Possible role of the dopamine D-1 receptor in the sensorimotor gating deficits induced by high-fat diet

  Chisato Wakabayashi; Tadahiro Numakawa; Yoshiko Ooshima; Kotaro Hattori; Hiroshi Kunugi

  PSYCHOPHARMACOLOGY SPRINGER 232 (24) 4393 - 4400 0033-3158 2015/12 [Refereed]
  
• Self-amplified BDNF transcription is a regulatory system for synaptic maturation in cultured cortical neurons

  Shingo Nakajima; Tadahiro Numakawa; Naoki Adachi; Yoshiko Ooshima; Haruki Odaka; Aya Yoshimura; Hiroshi Kunugi

  NEUROCHEMISTRY INTERNATIONAL PERGAMON-ELSEVIER SCIENCE LTD 91 55 - 61 0197-0186 2015/12 [Refereed]
  
• Effect of electroconvulsive therapy on gray matter volume in major depressive disorder

  Miho Ota; Takamasa Noda; Noriko Sato; Mitsutoshi Okazaki; Masatoshi Ishikawa; Kotaro Hattori; Hiroaki Hori; Daimei Sasayama; Toshiya Teraishi; Daichi Sone; Hiroshi kunugi

  JOURNAL OF AFFECTIVE DISORDERS ELSEVIER SCIENCE BV 186 186 - 191 0165-0327 2015/11 [Refereed]
  
• C-13-tryptophan breath test detects increased catabolic turnover of tryptophan along the kynurenine pathway in patients with major depressive disorder

  Toshiya Teraishi; Hiroaki Hori; Daimei Sasayama; Junko Matsuo; Shintaro Ogawa; Miho Ota; Kotaro Hattori; Masahiro Kajiwara; Teruhiko Higuchi; Hiroshi Kunugi

  SCIENTIFIC REPORTS NATURE PUBLISHING GROUP 5 15994  2045-2322 2015/11 [Refereed]
  
• Neuromyelitis optica spectrum disorder and multiple sclerosis: Differentiation by a multimodal approach

  Miho Ota; Noriko Sato; Tomoko Okamoto; Takamasa Noda; Manabu Araki; Takashi Yamamura; Hiroshi Kunugi

  MULTIPLE SCLEROSIS AND RELATED DISORDERS ELSEVIER SCI LTD 4 (6) 515 - 520 2211-0348 2015/11 [Refereed]
  
• 精神医学のフロンティア 健常者の感覚運動フィルター機構に対するL-テアニンの影響

  太田 深秀; 若林 千里; 松尾 淳子; 木下 裕紀子; 堀 弘明; 服部 功太郎; 篠山 大明; 寺石 俊也; 大部 聡子; 小澤 隼人; 大久保 勉; 功刀 浩

  精神神経学雑誌 (公社)日本精神神経学会 117 (10) 813 - 819 0033-2658 2015/10
• Effect of L-theanine on glutamatergic function in patients with schizophrenia

  Miho Ota; Chisato Wakabayashi; Noriko Sato; Hiroaki Hori; Kotaro Hattori; Toshiya Teraishi; Hayato Ozawa; Tsutomu Okubo; Hiroshi Kunugi

  ACTA NEUROPSYCHIATRICA CAMBRIDGE UNIV PRESS 27 (5) 291 - 296 1601-5215 2015/10 [Refereed]
  
• Biochemical markers subtyping major depressive disorder

  Hiroshi Kunugi; Hiroaki Hori; Shintaro Ogawa

  PSYCHIATRY AND CLINICAL NEUROSCIENCES WILEY 69 (10) 597 - 608 1323-1316 2015/10 [Refereed]
  
• 統合失調症におけるテアニンの作用(Effect of L-theanine on glutamatergic function in patients with schizophrenia)

  太田 深秀; 若林 千里; 佐藤 典子; 堀 弘明; 服部 功太郎; 寺石 俊也; 小澤 隼人; 大久保 勉; 功刀 浩

  日本生物学的精神医学会・日本神経精神薬理学会合同年会プログラム・抄録集 日本生物学的精神医学会・日本神経精神薬理学会 37回・45回 206 - 206 2015/09
• 服薬していない外来うつ病患者における末梢血遺伝子発現プロファイル 網羅的遺伝子発現と候補遺伝子発現の統合的解析(Blood-based gene expression signatures of medication-free outpatients with major depressive disorder: integrative genome-wide and candidate gene analyses)

  堀 弘明; 篠山 大明; 寺石 俊也; 山本 宜子; 中村 誠二; 太田 深秀; 服部 功太郎; 金 吉晴; 樋口 輝彦; 功刀 浩

  日本生物学的精神医学会・日本神経精神薬理学会合同年会プログラム・抄録集 日本生物学的精神医学会・日本神経精神薬理学会 37回・45回 199 - 199 2015/09
• 精神疾患脳脊髄液バイオリソースの構築とバイオマーカーの探索

  服部 功太郎; 篠山 大明; 吉田 寿美子; 功刀 浩

  日本生物学的精神医学会・日本神経精神薬理学会合同年会プログラム・抄録集 日本生物学的精神医学会・日本神経精神薬理学会 37回・45回 213 - 213 2015/09
• Glucocorticoid affects dendritic transport of BDNF-containing vesicles

  Naoki Adachi; Tadahiro Numakawa; Shingo Nakajima; Masashi Fukuoka; Haruki Odaka; Yusuke Katanuma; Yoshiko Ooshima; Hirohiko Hohjoh; Hiroshi Kunugi

  SCIENTIFIC REPORTS NATURE PUBLISHING GROUP 5 12684  2045-2322 2015/08 [Refereed]
  
• IL-1 receptor-antagonist (IL-1Ra) knockout mice show anxiety-like behavior by aging

  Chisato Wakabayashi; Tadahiro Numakawa; Haruki Odaka; Yoshiko Ooshima; Yuji Kiyama; Toshiya Manabe; Hiroshi Kunugi; Yoichiro Iwakura

  NEUROSCIENCE LETTERS ELSEVIER IRELAND LTD 599 20 - 25 0304-3940 2015/07 [Refereed]
  
• Increased cerebrospinal fluid fibrinogen in major depressive disorder

  Kotaro Hattori; Miho Ota; Daimei Sasayama; Sumiko Yoshida; Ryo Matsumura; Tomoko Miyakawa; Yuuki Yokota; Shinobu Yamaguchi; Takamasa Noda; Toshiya Teraishi; Hiroaki Hori; Teruhiko Higuchi; Shinichi Kohsaka; Yu-ichi Goto; Hiroshi Kunugi

  SCIENTIFIC REPORTS NATURE PUBLISHING GROUP 5 11412  2045-2322 2015/06 [Refereed]
  
• White matter abnormalities in major depressive disorder with melancholic and atypical features: A diffusion tensor imaging study

  Miho Ota; Takamasa Noda; Noriko Sato; Kotaro Hattori; Hiroaki Hori; Daimei Sasayama; Toshiya Teraishi; Anna Nagashima; Satoko Obu; Teruhiko Higuchi; Hiroshi Kunugi

  PSYCHIATRY AND CLINICAL NEUROSCIENCES WILEY-BLACKWELL 69 (6) 360 - 368 1323-1316 2015/06 [Refereed]
  
• Identification of Rare, Single-Nucleotide Mutations in NDE1 and Their Contributions to Schizophrenia Susceptibility.

  Hiroki Kimura; Daisuke Tsuboi; Chenyao Wang; Itaru Kushima; Takayoshi Koide; Masashi Ikeda; Yoshimi Iwayama; Tomoko Toyota; Noriko Yamamoto; Shohko Kunimoto; Yukako Nakamura; Akira Yoshimi; Masahiro Banno; Jingrui Xing; Yuto Takasaki; Mami Yoshida; Branko Aleksic; Yota Uno; Takashi Okada; Tetsuya Iidaka; Toshiya Inada; Michio Suzuki; Hiroshi Ujike; Hiroshi Kunugi; Tadafumi Kato; Takeo Yoshikawa; Nakao Iwata; Kozo Kaibuchi; Norio Ozaki

  Schizophrenia bulletin 41 (3) 744 - 53 0586-7614 2015/05 [Refereed]
  
• Methamphetamine-sensitized rats show augmented dopamine release to methylphenidate stimulation: a positron emission tomography using [18F]fallypride.

  Ota M; Ogawa S; Kato K; Wakabayashi C; Kunugi H

  Psychiatry research Elsevier BV 232 (1) 92 - 97 0165-1781 2015/04 [Refereed]
  
• Exposure to social defeat stress in adolescence improves the working memory and anxiety-like behavior of adult female rats with intrauterine growth restriction, independently of hippocampal neurogenesis

  Miyako Furuta; Midori Ninomiya-Baba; Shuichi Chiba; Toshiya Funabashi; Tatsuo Akema; Hiroshi Kunugi

  HORMONES AND BEHAVIOR ACADEMIC PRESS INC ELSEVIER SCIENCE 70 30 - 37 0018-506X 2015/04 [Refereed]
  
• Autistic-Like Traits in Adult Patients with Mood Disorders and Schizophrenia

  Junko Matsuo; Yoko Kamio; Hidetoshi Takahashi; Miho Ota; Toshiya Teraishi; Hiroaki Hori; Anna Nagashima; Reiko Takei; Teruhiko Higuchi; Nobutaka Motohashi; Hiroshi Kunugi

  PLOS ONE PUBLIC LIBRARY SCIENCE 10 (4) e0122711  1932-6203 2015/04 [Refereed]
  
• Effect of L-theanine on glutamatergic function in patients with schizophrenia

  Miho Ota; Chisato Wakabayashi; Noriko Sato; Hiroaki Hori; Kotaro Hattori; Toshiya Teraishi; Hayato Ozawa; Tsutomu Okubo; Hiroshi Kunugi

  Acta Neuropsychiatrica Cambridge University Press 27 (5) 291 - 296 1601-5215 2015/03 [Refereed]
  
• 大型自然災害後のうつ病諸相 災害による食生活変化とうつ病

  相澤 恵美子; 石田 一希; 太田 深秀; 佐藤 晋爾; 朝田 隆; 功刀 浩

  Depression Frontier (株)医薬ジャーナル社 13 (1) 81 - 87 1347-8893 2015/03
• うつ病の病態仮説と分子マーカー

  功刀 浩

  精神科診断学 8 16 - 20 2015
• うつ病を生物学的に理解する．

  功刀 浩

  医学と薬学 72 1841 - 1849 2015
• Understanding the Essence of Psychosis Through Brain Science(Training Lecture)

  Kunugi Hiroshi

  Journal of Japan Academy of Psychiatric and Mental Health Nursing The Japan Academy of Psychiatric and Mental Health Nursing 24 (2) 26 - 35 0918-0621 2015
• Nutritional impairments in patients with depression

  Kunugi Hiroshi; Koga Norie; Ogawa Shintaro

  Japanese Journal of Biological Psychiatry Japanese Society of Biological Psychiatry 26 (1) 54 - 58 2186-6619 2015
• Inhibitors of Fatty Acid Amide Hydrolase and Monoacylglycerol Lipase: New Targets for Future Antidepressants

  Shintaro Ogawa; Hiroshi Kunugi

  CURRENT NEUROPHARMACOLOGY BENTHAM SCIENCE PUBL LTD 13 (6) 760 - 775 1570-159X 2015 [Refereed]
  
• Basic fibroblast growth factor induces miR-134 upregulation in astrocyte for cell maturation

  Tadahiro Numakawa; Shingo Nakajima; Noriko Yamamoto; Yoshiko Ooshima; Haruki Odaka; Kazuo Hashido; Naoki Adachi; Hiroshi Kunugi

  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS ACADEMIC PRESS INC ELSEVIER SCIENCE 456 (1) 465 - 470 0006-291X 2015/01 [Refereed]
  
• Reduced cerebrospinal fluid ethanolamine concentration in major depressive disorder

  Shintaro Ogawa; Kotaro Hattori; Daimei Sasayama; Yuki Yokota; Ryo Matsumura; Junko Matsuo; Miho Ota; Hiroaki Hori; Toshiya Teraishi; Sumiko Yoshida; Takamasa Noda; Yoshiaki Ohashi; Hajime Sato; Teruhiko Higuchi; Nobutaka Motohashi; Hiroshi Kunugi

  SCIENTIFIC REPORTS NATURE PUBLISHING GROUP 5 7796  2045-2322 2015/01 [Refereed]
  
• Personality in remitted major depressive disorder with single and recurrent episodes assessed with the Temperament and Character Inventory

  Toshiya Teraishi; Hiroaki Hori; Daimei Sasayama; Junko Matsuo; Shintaro Ogawa; Ikki Ishida; Anna Nagashima; Yukiko Kinoshita; Miho Ota; Kotaro Hattori; Teruhiko Higuchi; Hiroshi Kunugi

  PSYCHIATRY AND CLINICAL NEUROSCIENCES WILEY-BLACKWELL 69 (1) 3 - 11 1323-1316 2015/01 [Refereed]
  
• Serotonin and dopamine receptors in motivational and cognitive disturbances of schizophrenia

  Tomiki Sumiyoshi; Hiroshi Kunugi; Kazuyuki Nakagome

  FRONTIERS IN NEUROSCIENCE FRONTIERS RESEARCH FOUNDATION 8 1662-453X 2014/12 [Refereed]
  
• Altered coupling of regional cerebral blood flow and brain temperature in schizophrenia compared with bipolar disorder and healthy subjects

  Miho Ota; Noriko Sato; Koji Sakai; Mitsutoshi Okazaki; Norihide Maikusa; Kotaro Hattori; Hiroaki Hori; Toshiya Teraishi; Keigo Shimoji; Kei Yamada; Hiroshi Kunugi

  JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM SAGE PUBLICATIONS INC 34 (12) 1868 - 1872 0271-678X 2014/12 [Refereed]
  
• Microinjection of cocaine- and amphetamine-regulated transcript 55-102 peptide into the nucleus accumbens could modulate anxiety-related behavior in rats

  Hyung Shin Yoon; Naoki Adachi; Hiroshi Kunugi

  NEUROPEPTIDES CHURCHILL LIVINGSTONE 48 (6) 319 - 325 0143-4179 2014/12 [Refereed]
  
• New insight in expression, transport, and secretion of brain-derived neurotrophic factor: Implications in brain-related diseases.

  Naoki Adachi; Tadahiro Numakawa; Misty Richards; Shingo Nakajima; Hiroshi Kunugi

  World journal of biological chemistry 5 (4) 409 - 28 2014/11 [Refereed]
  
• Association between the common functional FKBP5 variant (rs1360780) and brain structure in a non-clinical population

  Takashi Fujii; Miho Ota; Hiroaki Hori; Kotaro Hattori; Toshiya Teraishi; Daimei Sasayama; Teruhiko Higuchi; Hiroshi Kunugi

  JOURNAL OF PSYCHIATRIC RESEARCH PERGAMON-ELSEVIER SCIENCE LTD 58 96 - 101 0022-3956 2014/11 [Refereed]
  
• Verification of the utility of the social responsiveness scale for adults in non-clinical and clinical adult populations in Japan

  Reiko Takei; Junko Matsuo; Hidetoshi Takahashi; Tokio Uchiyama; Hiroshi Kunugi; Yoko Kamio

  BMC PSYCHIATRY BIOMED CENTRAL LTD 14 302  1471-244X 2014/11 [Refereed]
  
• The common functional FKBP5 variant rs1360780 is associated with altered cognitive function in aged individuals

  Takashi Fujii; Miho Ota; Hiroaki Hori; Kotaro Hattori; Toshiya Teraishi; Junko Matsuo; Yukiko Kinoshita; Ikki Ishida; Anna Nagashima; Hiroshi Kunugi

  SCIENTIFIC REPORTS NATURE PUBLISHING GROUP 4 6696  2045-2322 2014/10 [Refereed]
  
• Temperament and character in remitted and symptomatic patients with schizophrenia: Modulation by the COMT Val158Met genotype

  Hiroaki Hori; Takashi Fujii; Noriko Yamamoto; Toshiya Teraishi; Miho Ota; Junko Matsuo; Yukiko Kinoshita; Ikki Ishida; Kotaro Hattori; Mitsutoshi Okazaki; Kunimasa Arima; Hiroshi Kunugi

  JOURNAL OF PSYCHIATRIC RESEARCH PERGAMON-ELSEVIER SCIENCE LTD 56 82 - 89 0022-3956 2014/09 [Refereed]
  
• Relationship between Lifetime Suicide Attempts and Schizotypal Traits in Patients with Schizophrenia

  Toshiya Teraishi; Hiroaki Hori; Daimei Sasayama; Junko Matsuo; Shintaro Ogawa; Ikki Ishida; Anna Nagashima; Yukiko Kinoshita; Miho Ota; Kotaro Hattori; Hiroshi Kunugi

  PLOS ONE PUBLIC LIBRARY SCIENCE 9 (9) e107739  1932-6203 2014/09 [Refereed]
  
• Plasma L-Tryptophan Concentration in Major Depressive Disorder: New Data and Meta-Analysis

  Shintaro Ogawa; Takashi Fujii; Norie Koga; Hiroaki Hori; Toshiya Teraishi; Kotaro Hattori; Takamasa Noda; Teruhiko Higuchi; Nobutaka Motohashi; Hiroshi Kunugi

  JOURNAL OF CLINICAL PSYCHIATRY PHYSICIANS POSTGRADUATE PRESS 75 (9) E906 - E915 0160-6689 2014/09 [Refereed]
  
• The role of brain-derived neurotrophic factor in comorbid depression: possible linkage with steroid hormones, cytokines, and nutrition

  Tadahiro Numakawa; Misty Richards; Shingo Nakajima; Naoki Adachi; Miyako Furuta; Haruki Odaka; Hiroshi Kunugi

  FRONTIERS IN PSYCHIATRY FRONTIERS MEDIA SA 5 136  1664-0640 2014/09 [Refereed]
  
• Characteristic distributions of regional cerebral blood flow changes in major depressive disorder patients: A pseudo-continuous arterial spin labeling (pCASL) study

  Miho Ota; Takamasa Noda; Noriko Sato; Kotaro Hattori; Toshiya Teraishi; Hiroaki Hori; Anna Nagashima; Keigo Shimoji; Teruhiko Higuchi; Hiroshi Kunugi

  JOURNAL OF AFFECTIVE DISORDERS ELSEVIER SCIENCE BV 165 59 - 63 0165-0327 2014/08 [Refereed]
  
• Increased protein and mRNA expression of resistin after dexamethasone administration

  D. Sasayama; H. Hori; S. Nakamura; N. Yamamoto; K. Hattori; T. Teraishi; M. Ota; H. Kunugi

  Hormone and Metabolic Research Georg Thieme Verlag 47 (6) 433 - 438 1439-4286 2014/07 [Refereed]
  
• Replication and Cross-Phenotype Study Based Upon Schizophrenia GWASs Data in the japanese Population: Support for Association of MHC Region with Psychosis

  Takeo Saito; Kenji Kondo; Yoshimi Iwayama; Ayu Shimasaki; Branko Aleksic; Kazuo Yamada; Tomoko Toyota; Eiji Hattori; Kosei Esaki; Hiroshi Ujike; Toshiya Inada; Hiroshi Kunugi; Tadafumi Kato; Takeo Yoshikawa; Norio Ozaki; Masashi Ikeda; Nakao Iwata

  AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS WILEY 165 (5) 421 - 427 1552-4841 2014/07 [Refereed]
  
• 【初診、初期治療-何を見逃してはならないか-II】初発精神病エピソードの初回面接

  堀 弘明; 功刀 浩

  精神科治療学 (株)星和書店 29 (7) 911 - 917 0912-1862 2014/07
• Phencyclidine Rapidly Decreases Neuronal mRNA of Brain-Derived Neurotrophic Factor

  Yusuke Katanuma; Tadahiro Numakawa; Naoki Adachi; Noriko Yamamoto; Yoshiko Ooshima; Haruki Odaka; Takafumi Inoue; Hiroshi Kunugi

  SYNAPSE WILEY-BLACKWELL 68 (6) 257 - 265 0887-4476 2014/06 [Refereed]
  
• QT Is Longer in Drug-Free Patients with Schizophrenia Compared with Age-Matched Healthy Subjects

  Kumiko Fujii; Yuji Ozeki; Hiroaki Okayasu; Yumiko Takano; Takahiro Shinozaki; Hiroaki Hori; Masami Orui; Minoru Horie; Hiroshi Kunugi; Kazutaka Shimoda

  PLOS ONE PUBLIC LIBRARY SCIENCE 9 (6) e98555  1932-6203 2014/06 [Refereed]
  
• Cabergoline, Dopamine D2 Receptor Agonist, Prevents Neuronal Cell Death under Oxidative Stress via Reducing Excitotoxicity

  Haruki Odaka; Tadahiro Numakawa; Naoki Adachi; Yoshiko Ooshima; Shingo Nakajima; Yusuke Katanuma; Takafumi Inoue; Hiroshi Kunugi

  PLOS ONE PUBLIC LIBRARY SCIENCE 9 (6) e99271  1932-6203 2014/06 [Refereed]
  
• Effect of L-theanine on sensorimotor gating in healthy human subjects

  Miho Ota; Chisato Wakabayashi; Junko Matsuo; Yukiko Kinoshita; Hiroaki Hori; Kotaro Hattori; Daimei Sasayama; Toshiya Teraishi; Satoko Obu; Hayato Ozawa; Hiroshi Kunugi

  PSYCHIATRY AND CLINICAL NEUROSCIENCES WILEY-BLACKWELL 68 (5) 337 - 343 1323-1316 2014/05 [Refereed]
  
• Pseudo-continuous arterial spin labeling MRI study of schizophrenic patients

  Miho Ota; Masanori Ishikawa; Noriko Sato; Mitsutoshi Okazaki; Norihide Maikusa; Hiroaki Hori; Kotaro Hattori; Toshiya Teraishi; Kimiteru Ito; Hiroshi Kunugi

  SCHIZOPHRENIA RESEARCH ELSEVIER SCIENCE BV 154 (1-3) 113 - 118 0920-9964 2014/04 [Refereed]
  
• Impairments in Brain-Derived Neurotrophic Factor-Induced Glutamate Release in Cultured Cortical Neurons Derived from Rats with Intrauterine Growth Retardation: Possible Involvement of Suppression of TrkB/Phospholipase C-gamma Activation

  Tadahiro Numakawa; Tomoya Matsumoto; Yoshiko Ooshima; Shuichi Chiba; Miyako Furuta; Aiko Izumi; Midori Ninomiya-Baba; Haruki Odaka; Kazuo Hashido; Naoki Adachi; Hiroshi Kunugi

  NEUROCHEMICAL RESEARCH SPRINGER/PLENUM PUBLISHERS 39 (4) 785 - 792 0364-3190 2014/04 [Refereed]
  
• Effect of the common functional FKBP5 variant (rs1360780) on the hypothalamic-pituitary-adrenal axis and peripheral blood gene expression

  Takashi Fujii; Hiroaki Hori; Miho Ota; Kotaro Hattori; Toshiya Teraishi; Daimei Sasayama; Noriko Yamamoto; Teruhiko Higuchi; Hiroshi Kunugi

  PSYCHONEUROENDOCRINOLOGY PERGAMON-ELSEVIER SCIENCE LTD 42 89 - 97 0306-4530 2014/04 [Refereed]
  
• Cognitive effects of the ANK3 risk variants in patients with bipolar disorder and healthy individuals

  Hiroaki Hori; Noriko Yamamoto; Toshiya Teraishi; Miho Ota; Takashi Fujii; Daimei Sasayama; Junko Matsuo; Yukiko Kinoshita; Kotaro Hattori; Anna Nagashima; Ikki Ishida; Norie Koga; Teruhiko Higuchi; Hiroshi Kunugi

  JOURNAL OF AFFECTIVE DISORDERS ELSEVIER SCIENCE BV 158 90 - 96 0165-0327 2014/04 [Refereed]
  
• 統合失調症患者の肥満と関連する食生活および服薬について

  古賀 賀恵; 服部 功太郎; 堀 弘明; 功刀 浩

  日本栄養・食糧学会大会講演要旨集 (公社)日本栄養・食糧学会 68回 268 - 268 2014/04
• うつ病における血漿中遊離アミノ酸濃度の変化

  小川 眞太朗; 山本 宣子; 堀 弘明; 寺石 俊也; 太田 深秀; 服部 功太郎; 篠山 大明; 松尾 淳子; 長島 杏那; 木下 裕紀子; 石田 一希; 古賀 賀恵; 樋口 輝彦; 功刀 浩

  日本栄養・食糧学会大会講演要旨集 (公社)日本栄養・食糧学会 68回 168 - 168 2014/04
• Teneurin-4 promotes cellular protrusion formation and neurite outgrowth through focal adhesion kinase signaling

  Nobuharu Suzuki; Tadahiro Numakawa; Joshua Chou; Susana de Vega; Chihiro Mizuniwa; Kaori Sekimoto; Naoki Adachi; Hiroshi Kunugi; Eri Arikawa-Hirasawa; Yoshihiko Yamada; Chihiro Akazawa

  FASEB JOURNAL FEDERATION AMER SOC EXP BIOL 28 (3) 1386 - 1397 0892-6638 2014/03 [Refereed]
  
• ITIH3 polymorphism may confer susceptibility to psychiatric disorders by altering the expression levels of GLT8D1

  Daimei Sasayama; Hiroaki Hori; Noriko Yamamoto; Seiji Nakamura; Toshiya Teraishi; Masahiko Tatsumi; Kotaro Hattori; Miho Ota; Teruhiko Higuchi; Hiroshi Kunugi

  JOURNAL OF PSYCHIATRIC RESEARCH PERGAMON-ELSEVIER SCIENCE LTD 50 79 - 83 0022-3956 2014/03 [Refereed]
  
• Benzodiazepines, benzodiazepine-like drugs, and typical antipsychotics impair manual dexterity in patients with schizophrenia

  Daimei Sasayama; Hiroaki Hori; Toshiya Teraishi; Kotaro Hattori; Miho Ota; Junko Matsuo; Yukiko Kinoshita; Mitsutoshi Okazaki; Kunimasa Arima; Naoji Amano; Teruhiko Higuchi; Hiroshi Kunugi

  JOURNAL OF PSYCHIATRIC RESEARCH PERGAMON-ELSEVIER SCIENCE LTD 49 37 - 42 0022-3956 2014/02 [Refereed]
  
• Cross-cultural comparisons of attitudes toward schizophrenia amongst the general population and physicians: A series of web-based surveys in Japan and the United States

  Misty Richards; Hiroaki Hori; Norman Sartorius; Hiroshi Kunugi

  PSYCHIATRY RESEARCH ELSEVIER IRELAND LTD 215 (2) 300 - 307 0165-1781 2014/02 [Refereed]
  
• A latent profile analysis of schizotypy, temperament and character in a nonclinical population: Association with neurocognition

  Hiroaki Hori; Toshiya Teraishi; Daimei Sasayama; Junko Matsuo; Yukiko Kinoshita; Miho Ota; Kotaro Hattori; Hiroshi Kunugi

  JOURNAL OF PSYCHIATRIC RESEARCH PERGAMON-ELSEVIER SCIENCE LTD 48 (1) 56 - 64 0022-3956 2014/01 [Refereed]
  
• Genetic association study between the detected risk variants based upon type II diabetes GWAS and psychotic disorders in the Japanese population

  Yusuke Kajio; Kenji Kondo; Takeo Saito; Yoshimi Iwayama; Branko Aleksic; Kazuo Yamada; Tomoko Toyota; Eiji Hattori; Hiroshi Ujike; Toshiya Inada; Hiroshi Kunugi; Tadafumi Kato; Takeo Yoshikawa; Norio Ozaki; Masashi Ikeda; Nakao Iwata

  JOURNAL OF HUMAN GENETICS NATURE PUBLISHING GROUP 59 (1) 54 - 56 1434-5161 2014/01 [Refereed]
  
• Psychological coping in depressed outpatients: Association with cortisol response to the combined dexamethasone/CRH test

  Hiroaki Hori; Toshiya Teraishi; Miho Ota; Kotaro Hattori; Junko Matsuo; Yukiko Kinoshita; Ikki Ishida; Anna Nagashima; Norie Koga; Teruhiko Higuchi; Hiroshi Kunugi

  JOURNAL OF AFFECTIVE DISORDERS ELSEVIER SCIENCE BV 152 441 - 447 0165-0327 2014/01 [Refereed]
  
• Phosphatase-Mediated Intracellular Signaling Contributes to Neuroprotection by Flavonoids of Iris tenuifolia

  Aldarmaa Jalsrai; Tadahiro Numakawa; Yoshiko Ooshima; Naoki Adachi; Hiroshi Kunugi

  AMERICAN JOURNAL OF CHINESE MEDICINE WORLD SCIENTIFIC PUBL CO PTE LTD 42 (1) 119 - 130 0192-415X 2014 [Refereed]
  
• Biomarkers and therapeutic targets of depressive disorder：A joint symposium of Max Planck Institute of Psychiatry and National Center of Neurology and Psychiatry, Japan

  Kunugi Hiroshi

  Japanese Journal of Biological Psychiatry Japanese Society of Biological Psychiatry 25 (1) 18 - 23 2186-6619 2014
• Serotonin and dopamine receptors in motivational and cognitive disturbances of schizophrenia

  Tomiki Sumiyoshi; Hiroshi Kunugi; Kazuyuki Nakagome

  Frontiers in Neuroscience Frontiers Media S.A. 8 (DEC) 395  1662-453X 2014 [Refereed]
  
• Hypothalamic-pituitary-adrenal axis hyperactivity and brain differences in healthy women

  Miho Ota; Hiroaki Hori; Noriko Sato; Daimei Sasayama; Kotaro Hattori; Toshiya Teraishi; Satoko Obu; Yasuhiro Nakata; Hiroshi Kunugi

  Neuropsychobiology 4 68 (4) 205 - 211 0302-282X 2013/12 [Refereed]
  
• Inhibition of Olanzapine-Induced Weight Gain by the Retinoid Analog AM-80

  M. Richards; S. Chiba; M. Ninomiya; C. Wakabayasi; H. Kunugi

  PHARMACOPSYCHIATRY GEORG THIEME VERLAG KG 46 (7) 267 - 273 0176-3679 2013/11 [Refereed]
  
• Replication in a Japanese population that a MIR30E gene variation is associated with schizophrenia.

  Yuichiro Watanabe; Yoshimi Iijima; Jun Egawa; Ayako Nunokawa; Naoshi Kaneko; Tadao Arinami; Hiroshi Ujike; Toshiya Inada; Nakao Iwata; Hiroshi Kunugi; Masanari Itokawa; Tsukasa Sasaki; Norio Ozaki; Ryota Hashimoto; Masako Shibuya; Hirofumi Igeta; Toshiyuki Someya

  Schizophrenia research 2-3 150 (2-3) 596 - 7 0920-9964 2013/11 [Refereed]
  
• Moderating effect of schizotypy on the relationship between smoking and neurocognition

  H. Hori; J. Matsuo; T. Teraishi; D. Sasayama; Y. Kawamoto; Y. Kinoshita; M. Ota; K. Hattori; H. Kunugi

  European Psychiatry 8 28 (8) 457 - 462 0924-9338 2013/10 [Refereed]
  
• Estrogen, predominantly via estrogen receptor α, attenuates postpartum-induced anxiety- and depression-like behaviors in female rats

  Miyako Furuta; Tadahiro Numakawa; Shuichi Chiba; Midori Ninomiya; Yu Kajiyama; Naoki Adachi; Tatsuo Akema; Hiroshi Kunugi

  Endocrinology 10 154 (10) 3807 - 3816 0013-7227 2013/10 [Refereed]
  
• ベンゾジアゼピン系薬剤、ベンゾジアゼピン様薬剤、定型抗精神病薬による統合失調症患者の手指巧緻性の低下

  篠山 大明; 堀 弘明; 寺石 俊也; 服部 功太郎; 太田 深秀; 松尾 淳子; 木下 裕紀子; 岡崎 光俊; 有馬 邦正; 天野 直二; 樋口 輝彦; 功刀 浩

  日本臨床精神神経薬理学会・日本神経精神薬理学会合同年会プログラム・抄録集 日本臨床精神神経薬理学会・日本神経精神薬理学会 23回・43回 219 - 219 2013/10
• Lack of association of EGR2 variants with bipolar disorder in Japanese population

  Shabeesh Balan; Kazuo Yamada; Yoshimi Iwayama; Tomoko Toyota; Tetsuo Ohnishi; Motoko Maekawa; Manabu Toyoshima; Yasuhide Iwata; Katsuald Suzuki; Mitsuru Kikuchi; Hiroshi Ujike; Toshiya Inada; Hiroshi Kunugi; Norio Ozaki; Nakao Iwata; Shinichiro Nanko; Tadafumi Kato; Takeo Yoshikawa

  GENE ELSEVIER SCIENCE BV 526 (2) 246 - 250 0378-1119 2013/09 [Refereed]
  
• Dopamine agonist-responsive depression

  Hiroaki Hori; Hiroshi Kunugi

  PSYCHOGERIATRICS WILEY-BLACKWELL 13 (3) 189 - 195 1346-3500 2013/09 [Refereed]
  
• 統合失調症の肥満と関連する要因について

  古賀 賀恵; 服部 功太郎; 堀 弘明; 功刀 浩

  New Diet Therapy (一社)日本臨床栄養協会 29 (2) 182 - 182 0910-7258 2013/09
• Possible association of CUX1 gene polymorphisms with antidepressant response in major depressive disorder

  D. Sasayama; A. Hiraishi; M. Tatsumi; K. Kamijima; M. Ikeda; W. Umene-Nakano; R. Yoshimura; J. Nakamura; N. Iwata; H. Kunugi

  PHARMACOGENOMICS JOURNAL NATURE PUBLISHING GROUP 13 (4) 354 - 358 1470-269X 2013/08 [Refereed]
  
• An association analysis of the cardiomyopathy-associated 5 (CMYA5) gene with schizophrenia in a Japanese population

  Masaomi Furukawa; Mamoru Tochigi; Takeshi Otowa; Tadao Arinami; Toshiya Inada; Hiroshi Ujike; Yuichiro Watanabe; Nakao Iwata; Masanari Itokawa; Hiroshi Kunugi; Ryota Hashimoto; Norio Ozaki; Chihiro Kakiuchi; Kiyoto Kasai; Tsukasa Sasaki

  PSYCHIATRIC GENETICS LIPPINCOTT WILLIAMS & WILKINS 23 (4) 179 - 180 0955-8829 2013/08 [Refereed]
  
• Genetic Variants on 3q21 and in the Sp8 Transcription Factor Gene (SP8) as Susceptibility Loci for Psychotic Disorders: A Genetic Association Study

  Kenji Kondo; Masashi Ikeda; Yusuke Kajio; Takeo Saito; Yoshimi Iwayama; Branko Aleksic; Kazuo Yamada; Tomoko Toyota; Eiji Hattori; Hiroshi Ujike; Toshiya Inada; Hiroshi Kunugi; Tadafumi Kato; Takeo Yoshikawa; Norio Ozaki; Nakao Iwata

  PLOS ONE PUBLIC LIBRARY SCIENCE 8 (8) e70964  1932-6203 2013/08 [Refereed]
  
• 【うつ病の亜型分類への展望-その2】うつ病のバイオマーカーと亜型 特に視床下部-下垂体-副腎系機能との関連について

  功刀 浩; 堀 弘明

  臨床精神医学 (株)アークメディア 42 (8) 991 - 998 0300-032X 2013/08
• Abnormalities of cerebral blood flow in multiple sclerosis: A pseudocontinuous arterial spin labeling MRI study

  Miho Ota; Noriko Sato; Yasuhiro Nakata; Kimiteru Ito; Kouhei Kamiya; Norihide Maikusa; Masafumi Ogawa; Tomoko Okamoto; Satoko Obu; Takamasa Noda; Manabu Araki; Takashi Yamamura; Hiroshi Kunugi

  Magnetic Resonance Imaging 6 31 (6) 990 - 995 0730-725X 2013/07 [Refereed]
  
• Possible association between common variants of the phenylalanine hydroxylase (PAH) gene and memory performance in healthy adults

  Toshiya Teraishi; Daimei Sasayama; Hiroaki Hori; Noriko Yamamoto; Takashi Fujii; Junko Matsuo; Anna Nagashima; Yukiko Kinoshita; Kotaro Hattori; Miho Ota; Sayaka Fujii; Hiroshi Kunugi

  BEHAVIORAL AND BRAIN FUNCTIONS BIOMED CENTRAL LTD 9 30  1744-9081 2013/07 [Refereed]
  
• BRAIN-DERIVED NEUROTROPHIC FACTOR AND GLUCOCORTICOIDS: RECIPROCAL INFLUENCE ON THE CENTRAL NERVOUS SYSTEM

  T. Numakawa; N. Adachi; M. Richards; S. Chiba; H. Kunugi

  NEUROSCIENCE PERGAMON-ELSEVIER SCIENCE LTD 239 157 - 172 0306-4522 2013/06 [Refereed]
  
• Genome-wide association study of schizophrenia using microsatellite markers in the Japanese population

  Hiroki Shibata; Ken Yamamoto; Zhu Sun; Akira Oka; Hidetoshi Inoko; Tadao Arinami; Toshiya Inada; Hiroshi Ujike; Masanari Itokawa; Mamoru Tochigi; Yuichiro Watanabe; Toshiyuki Someya; Hiroshi Kunugi; Tatsuyo Suzuki; Nakao Iwata; Norio Ozaki; Yasuyuki Fukumaki

  PSYCHIATRIC GENETICS LIPPINCOTT WILLIAMS & WILKINS 23 (3) 117 - 123 0955-8829 2013/06 [Refereed]
  
• 緑茶、コーヒーを飲む習慣と大うつ病との関連

  古賀 賀恵; 服部 功太郎; 堀 弘明; 功刀 浩

  New Diet Therapy (一社)日本臨床栄養協会 29 (1) 31 - 38 0910-7258 2013/06
• Relationship of temperament and character with cortisol reactivity to the combined dexamethasone/CRH test in depressed outpatients

  Hiroaki Hori; Toshiya Teraishi; Daimei Sasayama; Kotaro Hattori; Miyako Hashikura; Teruhiko Higuchi; Hiroshi Kunugi

  JOURNAL OF AFFECTIVE DISORDERS ELSEVIER SCIENCE BV 147 (1-3) 128 - 136 0165-0327 2013/05 [Refereed]
  
• Validation of computer-administered clinical rating scale: Hamilton Depression Rating Scale assessment with Interactive Voice Response technology Japanese version

  Hiroshi Kunugi; Norie Koga; Miyako Hashikura; Takamasa Noda; Yu Shimizu; Takayuki Kobayashi; Jun Yamanaka; Noriaki Kanemoto; Teruhiko Higuchi

  PSYCHIATRY AND CLINICAL NEUROSCIENCES WILEY-BLACKWELL 67 (4) 253 - 258 1323-1316 2013/05 [Refereed]
  
• ストレスとうつ病における白質異常 画像・バイオマーカー研究から

  功刀 浩; 太田 深秀; 堀 弘明; 服部 功太郎

  精神神経学雑誌 (公社)日本精神神経学会 (2013特別) S - 497 0033-2658 2013/05
• Phencyclidine-Induced Decrease of Synaptic Connectivity via Inhibition of BDNF Secretion in Cultured Cortical Neurons

  Naoki Adachi; Tadahiro Numakawa; Emi Kumamaru; Chiaki Itami; Shuichi Chiba; Yoshimi Iijima; Misty Richards; Ritsuko Katoh-Semba; Hiroshi Kunugi

  CEREBRAL CORTEX OXFORD UNIV PRESS INC 23 (4) 847 - 858 1047-3211 2013/04 [Refereed]
  
• [Personality dimensions in major depressive disorder predict cortisol reactivity to the combined dexamethasone/CRH test].

  Hori H; Teraishi T; Sasayama D; Hattori K; Hashikura M; Higuchi T; Kunugi H

  Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology 33 (2) 61 - 63 1340-2544 2013/04 [Refereed]
  
• 大うつ病性障害におけるパーソナリティはコルチゾール反応性を予測する デキサメタゾン/CRHテストによる検討

  堀 弘明; 寺石 俊也; 篠山 大明; 服部 功太郎; 橋倉 都; 樋口 輝彦; 功刀 浩

  日本神経精神薬理学雑誌 (一社)日本神経精神薬理学会 33 (2) 61 - 63 1340-2544 2013/04
• A population-specific uncommon variant in GRIN3A associated with schizophrenia.

  Atsushi Takata; Yoshimi Iwayama; Yasuhisa Fukuo; Masashi Ikeda; Tomo Okochi; Motoko Maekawa; Tomoko Toyota; Kazuo Yamada; Eiji Hattori; Tetsuo Ohnishi; Manabu Toyoshima; Hiroshi Ujike; Toshiya Inada; Hiroshi Kunugi; Norio Ozaki; Shinichiro Nanko; Kazuhiko Nakamura; Norio Mori; Shigenobu Kanba; Nakao Iwata; Tadafumi Kato; Takeo Yoshikawa

  Biological psychiatry 6 73 (6) 532 - 9 0006-3223 2013/03 [Refereed]
  
• Multimodal image analysis of sensorimotor gating in healthy women

  Miho Ota; Noriko Sato; Junko Matsuo; Yukiko Kinoshita; Yumiko Kawamoto; Hiroaki Hori; Toshiya Teraishi; Daimei Sasayama; Kotaro Hattori; Satoko Obu; Yasuhiro Nakata; Hiroshi Kunugi

  BRAIN RESEARCH ELSEVIER SCIENCE BV 1499 61 - 68 0006-8993 2013/03 [Refereed]
  
• 脳脊髄液を用いた統合失調症バイオマーカーの開発

  服部 功太郎; 篠山 大明; 功刀 浩

  精神薬療研究年報 (公財)先進医薬研究振興財団 (45) 57 - 58 1346-1702 2013/03
• 統合失調症認知機能簡易評価尺度日本語版(BACS-J)標準化の試み

  兼田 康宏; 住吉 太幹; 中込 和幸; 池澤 聰; 大森 哲郎; 古郡 規雄; 功刀 浩; 松尾 淳子; 宮本 聖也; 中村 純; 久住 一郎; 岡久 祐子; 小林 正義; 岡村 愛子; 鈴木 雄太郎; 管 心; 尾崎 紀夫; 吉田 泰介; 長田 泉美; 加藤 淳一; 浦田 暁菜; 佐久間 寛之; 永嶌 朋久; 石郷岡 純; 船橋 英樹; 羽下 路子; 赤澤 将文; 芳賀 大輔; 羽鳥 乃路; 原田 俊樹; 中谷 真樹; 児嶋 亮; 上原 優子; 松本 香子

  精神医学 (株)医学書院 55 (2) 167 - 175 0488-1281 2013/02
• [Distinguishing normal women from those with schizophrenia by means of MRI].

  Ota M; Sato N; Ishikawa M; Hori H; Sasayama D; Hattori K; Teraishi T; Obu S; Nakata Y; Nemoto K; Moriguchi Y; Hashimoto R; Kunugi H

  Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica 12 115 (12) 1171 - 1177 0033-2658 2013 [Refereed]
  
• Increased cerebrospinal fluid interleukin-6 levels in patients with schizophrenia and those with major depressive disorder

  Daimei Sasayama; Kotaro Hattori; Chisato Wakabayashi; Toshiya Teraishi; Hiroaki Hori; Miho Ota; Sumiko Yoshida; Kunimasa Arima; Teruhiko Higuchi; Naoji Amano; Hiroshi Kunugi

  Journal of Psychiatric Research Elsevier Ltd 47 (3) 401 - 406 1879-1379 2013 [Refereed]
  
• Identification of Single Nucleotide Polymorphisms Regulating Peripheral Blood mRNA Expression with Genome-Wide Significance: An eQTL Study in the Japanese Population

  Daimei Sasayama; Hiroaki Hori; Seiji Nakamura; Ryo Miyata; Toshiya Teraishi; Kotaro Hattori; Miho Ota; Noriko Yamamoto; Teruhiko Higuchi; Naoji Amano; Hiroshi Kunugi

  PLOS ONE PUBLIC LIBRARY SCIENCE 8 (1) e54967  1932-6203 2013/01 [Refereed]
  
• Differential Diagnosis Tool for Parkinsonian Syndrome Using Multiple Structural Brain Measures

  Miho Ota; Yasuhiro Nakata; Kimiteru Ito; Kouhei Kamiya; Masafumi Ogawa; Miho Murata; Satoko Obu; Hiroshi Kunugi; Noriko Sato

  COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE HINDAWI PUBLISHING CORPORATION 2013 571289  1748-670X 2013 [Refereed]
  
• Discrimination between schizophrenia and major depressive disorder by magnetic resonance imaging of the female brain

  Miho Ota; Masanori Ishikawa; Noriko Sato; Hiroaki Hori; Daimei Sasayama; Kotaro Hattori; Toshiya Teraishi; Takamasa Noda; Satoko Obu; Yasuhiro Nakata; Teruhiko Higuchi; Hiroshi Kunugi

  Journal of Psychiatric Research Elsevier Ltd 47 (10) 1383 - 1388 1879-1379 2013 [Refereed]
  
• PHENYLALANINE KINETICS IN SCHIZOPHRENIA PATIENTS DETECTED BY C-13-PHENYLALANINE BREATH TEST

  Teraishi T; Ozeki Y; Hori H; Sasayama D; Chiba S; Yamamoto N; Tanaka H; Iijima Y; Matsuo J; Kawamoto Y; Kinoshita Y; Hattori K; Ota M; Kajiwara M; Terada S; Higuchi T; Kunugi H

  European Psychiatry 28 2013 [Refereed]
  
• Neurotrophin Bdnf and Novel Molecular Targets in Depression Pathogenesis.

  Numakawa T; Nakajima S; Adachi N; Richards M; Kunugi H

  J Neurol Transl Neurosci. 1 1021  2013 [Refereed]
  
• Schizotypy and genetic loading for schizophrenia impact upon neuropsychological status in bipolar II and unipolar major depressive disorders

  Hiroaki Hori; Junko Matsuo; Toshiya Teraishi; Daimei Sasayama; Yumiko Kawamoto; Yukiko Kinoshita; Kotaro Hattori; Miyako Hashikura; Teruhiko Higuchi; Hiroshi Kunugi

  JOURNAL OF AFFECTIVE DISORDERS ELSEVIER SCIENCE BV 142 (1-3) 225 - 232 0165-0327 2012/12 [Refereed]
  
• Schizotypal trait in healthy women is associated with a shift away from dextrality on a spatial motor control task, but not on a force control task

  Hiroaki Hori; Toshiya Teraishi; Daimei Sasayama; Kotaro Hattori; Miho Ota; Junko Matsuo; Yumiko Kawamoto; Yukiko Kinoshita; Hiroshi Kunugi

  PSYCHIATRY RESEARCH ELSEVIER IRELAND LTD 200 (2-3) 629 - 634 0165-1781 2012/12 [Refereed]
  
• GTP cyclohydrolase 1 gene haplotypes as predictors of SSRI response in Japanese patients with major depressive disorder

  Taro Kishi; Hiroshi Ichinose; Reiji Yoshimura; Yasuhisa Fukuo; Tsuyoshi Kitajima; Toshiya Inada; Hiroshi Kunugi; Tadafumi Kato; Takeo Yoshikawa; Hiroshi Ujike; Giovanna M. Musso; Wakako Umene-Nakano; Jun Nakamura; Norio Ozaki; Nakao Iwata

  JOURNAL OF AFFECTIVE DISORDERS ELSEVIER SCIENCE BV 142 (1-3) 315 - 322 0165-0327 2012/12 [Refereed]
  
• Discrimination of female schizophrenia patients from healthy women using multiple structural brain measures obtained with voxel-based morphometry

  Miho Ota; Noriko Sato; Masanori Ishikawa; Hiroaki Hori; Daimei Sasayama; Kotaro Hattori; Toshiya Teraishi; Satoko Obu; Yasuhiro Nakata; Kiyotaka Nemoto; Yoshiya Moriguchi; Ryota Hashimoto; Hiroshi Kunugi

  PSYCHIATRY AND CLINICAL NEUROSCIENCES WILEY-BLACKWELL 66 (7) 611 - 617 1323-1316 2012/12 [Refereed]
  
• The influence of glucocorticoids on neuronal survival and synaptic function

  Tadahiro Numakawa; Naoki Adachi; Misty Richards; Shuichi Chiba; Hiroshi Kunugi

  Biomolecular Concepts Walter de Gruyter GmbH 3 (6) 495 - 504 1868-503X 2012/12 [Refereed]
  
• Pharmacotherapeutic Determinants for QTc Interval Prolongation in Japanese Patients with Mood Disorder

  H. Okayasu; Y. Ozeki; K. Fujii; Y. Takano; Y. Saeki; H. Hori; M. Horie; T. Higuchi; H. Kunugi; K. Shimoda

  PHARMACOPSYCHIATRY GEORG THIEME VERLAG KG 45 (7) 279 - 283 0176-3679 2012/11 [Refereed]
  
• Chronic restraint stress causes anxiety- and depression-like behaviors, downregulates glucocorticoid receptor expression, and attenuates glutamate release induced by brain-derived neurotrophic factor in the prefrontal cortex

  Shuichi Chiba; Tadahiro Numakawa; Midori Ninomiya; Misty C. Richards; Chisato Wakabayashi; Hiroshi Kunugi

  PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY PERGAMON-ELSEVIER SCIENCE LTD 39 (1) 112 - 119 0278-5846 2012/10 [Refereed]
  
• An evaluation of polymorphisms in casein kinase 1 delta and epsilon genes in major psychiatric disorders

  Shinji Matsunaga; Masashi Ikeda; Taro Kishi; Yasuhisa Fukuo; Branko Aleksic; Reiji Yoshimura; Tomo Okochi; Yoshio Yamanouchi; Yoko Kinoshita; Kunihiro Kawashima; Wakako Umene-Nakano; Toshiya Inada; Hiroshi Kunugi; Tadafumi Kato; Takeo Yoshikawa; Hiroshi Ujike; Jun Nakamura; Norio Ozaki; Tsuyoshi Kitajima; Nakao Iwata

  NEUROSCIENCE LETTERS ELSEVIER IRELAND LTD 529 (1) 66 - 69 0304-3940 2012/10 [Refereed]
  
• Intrauterine growth retardation neurons show a reduction in BDNF-mediated neuronal function

  Y. Ooshima; T. Numakawa; S. Chiba; M. Furuta; N. Adachi; H. Kunugi

  JOURNAL OF NEUROCHEMISTRY WILEY-BLACKWELL 123 76 - 76 0022-3042 2012/10 [Refereed]
  
• MicroRNA-132 induction following bFGF stimulation in glial and neural cultures

  N. Yamamoto; T. Numakawa; S. Chiba; M. Richards; Y. Ooshima; S. Kishi; K. Hashido; N. Adachi; H. Kunugi

  JOURNAL OF NEUROCHEMISTRY WILEY-BLACKWELL 123 118 - 118 0022-3042 2012/10 [Refereed]
  
• Suppressed release of BDNF contributes to the phencyclidine-caused loss of synapses

  N. Adachi; T. Numakawa; E. Kumamaru; C. Itami; S. Chiba; Y. Iijima; M. Richards; R. Katoh-Semba; H. Kunugi

  JOURNAL OF NEUROCHEMISTRY WILEY-BLACKWELL 123 12 - 12 0022-3042 2012/10 [Refereed]
  
• Effects of the CACNA1C risk allele on neurocognition in patients with schizophrenia and healthy individuals

  Hiroaki Hori; Noriko Yamamoto; Takashi Fujii; Toshiya Teraishi; Daimei Sasayama; Junko Matsuo; Yumiko Kawamoto; Yukiko Kinoshita; Miho Ota; Kotaro Hattori; Masahiko Tatsumi; Kunimasa Arima; Hiroshi Kunugi

  SCIENTIFIC REPORTS NATURE PUBLISHING GROUP 2 634  2045-2322 2012/09 [Refereed]
  
• うつ病患者における血漿中L-トリプトファン濃度の比較および先行研究のメタアナリシス

  小川 眞太朗; 藤井 崇; 古賀 賀恵; 堀 弘明; 服部 功太郎; 功刀 浩

  New Diet Therapy (一社)日本臨床栄養協会 28 (2) 132 - 132 0910-7258 2012/09
• 緑茶を飲む習慣とうつ病リスクとの関連

  古賀 賀恵; 服部 功太郎; 堀 弘明; 功刀 浩

  New Diet Therapy (一社)日本臨床栄養協会 28 (2) 141 - 141 0910-7258 2012/09
• うつ病の栄養学的検討(第2報)

  功刀 浩; 古賀 賀恵; 堀 弘明; 服部 功太郎

  New Diet Therapy (一社)日本臨床栄養協会 28 (2) 150 - 150 0910-7258 2012/09
• Possible impact of ADRB3 Trp64Arg polymorphism on BMI in patients with schizophrenia

  Daimei Sasayama; Hiroaki Hori; Toshiya Teraishi; Kotaro Hattori; Miho Ota; Masahiko Tatsumi; Teruhiko Higuchi; Naoji Amano; Hiroshi Kunugi

  PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY PERGAMON-ELSEVIER SCIENCE LTD 38 (2) 341 - 344 0278-5846 2012/08 [Refereed]
  
• Negative correlation between cerebrospinal fluid oxytocin levels and negative symptoms of male patients with schizophrenia

  Daimei Sasayama; Kotaro Hattori; Toshiya Teraishi; Hiroaki Hori; Miho Ota; Sumiko Yoshida; Kunimasa Arima; Teruhiko Higuchi; Naoji Amano; Hiroshi Kunugi

  SCHIZOPHRENIA RESEARCH ELSEVIER SCIENCE BV 139 (1-3) 201 - 206 0920-9964 2012/08 [Refereed]
  
• The hypothalamic-pituitary-adrenal axis and depressive disorder: Recent progress

  Hiroshi Kunugi; Hiroaki Hori; Tadahiro Numakawa; Miho Ota

  Japanese Journal of Neuropsychopharmacology 4 32 (4) 203 - 209 1340-2544 2012/08 [Refereed]
  
• 【うつ病の最先端脳科学的研究とその臨床応用】視床下部-下垂体-副腎系とうつ病 最近の展開

  功刀 浩; 堀 弘明; 沼川 忠広; 太田 深秀

  日本神経精神薬理学雑誌 (一社)日本神経精神薬理学会 32 (4) 203 - 209 1340-2544 2012/08
• Glutamatergic changes in the cerebral white matter associated with schizophrenic exacerbation

  M. Ota; M. Ishikawa; N. Sato; H. Hori; D. Sasayama; K. Hattori; T. Teraishi; Y. Nakata; H. Kunugi

  ACTA PSYCHIATRICA SCANDINAVICA WILEY-BLACKWELL 126 (1) 72 - 78 0001-690X 2012/07 [Refereed]
  
• Frontal and right temporal activations correlate negatively with depression severity during verbal fluency task: A multi-channel near-infrared spectroscopy study

  Takamasa Noda; Sumiko Yoshida; Taro Matsuda; Nagahisa Okamoto; Kota Sakamoto; Shunsuke Koseki; Yotaro Numachi; Eisuke Matsushima; Hiroshi Kunugi; Teruhiko Higuchi

  JOURNAL OF PSYCHIATRIC RESEARCH PERGAMON-ELSEVIER SCIENCE LTD 46 (7) 905 - 912 0022-3956 2012/07 [Refereed]
  
• C-13-phenylalanine breath test detects altered phenylalanine kinetics in schizophrenia patients

  T. Teraishi; Y. Ozeki; H. Hori; D. Sasayama; S. Chiba; N. Yamamoto; H. Tanaka; Y. Iijima; J. Matsuo; Y. Kawamoto; Y. Kinoshita; K. Hattori; M. Ota; M. Kajiwara; S. Terada; T. Higuchi; H. Kunugi

  TRANSLATIONAL PSYCHIATRY NATURE PUBLISHING GROUP 2 e119  2158-3188 2012/05 [Refereed]
  
• A two-stage case-control association study between the tryptophan hydroxylase 2 (TPH2) gene and schizophrenia in a Japanese population

  Yuichiro Watanabe; Jun Egawa; Yoshimi Iijima; Ayako Nunokawa; Naoshi Kaneko; Masako Shibuya; Tadao Arinami; Hiroshi Ujike; Toshiya Inada; Nakao Iwata; Mamoru Tochigi; Hiroshi Kunugi; Masanari Itokawa; Norio Ozaki; Ryota Hashimoto; Toshiyuki Someya

  SCHIZOPHRENIA RESEARCH ELSEVIER SCIENCE BV 137 (1-3) 264 - 266 0920-9964 2012/05 [Refereed]
  
• Association between the functional polymorphism (C3435T) of the gene encoding P-glycoprotein (ABCB1) and major depressive disorder in the Japanese population

  Takashi Fujii; Miho Ota; Hiroaki Hori; Daimei Sasayama; Kotaro Hattori; Toshiya Teraishi; Noriko Yamamoto; Miyako Hashikura; Masahiko Tatsumi; Teruhiko Higuchi; Hiroshi Kunugi

  JOURNAL OF PSYCHIATRIC RESEARCH PERGAMON-ELSEVIER SCIENCE LTD 46 (4) 555 - 559 0022-3956 2012/04 [Refereed]
  
• Association of cognitive performance with interleukin-6 receptor Asp358Ala polymorphism in healthy adults

  Daimei Sasayama; Hiroaki Hori; Toshiya Teraishi; Kotaro Hattori; Miho Ota; Junko Matsuo; Yumiko Kawamoto; Yukiko Kinoshita; Naoji Amano; Hiroshi Kunugi

  JOURNAL OF NEURAL TRANSMISSION SPRINGER WIEN 119 (3) 313 - 318 0300-9564 2012/03 [Refereed]
  
• 治療抵抗性うつ病に対するドーパミン作動薬の有効性に関する研究

  功刀 浩; 堀 弘明; 千葉 秀一; 沼川 忠広

  精神薬療研究年報 (公財)先進医薬研究振興財団 (44) 51 - 52 1346-1702 2012/03
• Behavioral and molecular evidence for psychotropic effects in L-theanine

  Chisato Wakabayashi; Tadahiro Numakawa; Midori Ninomiya; Shuichi Chiba; Hiroshi Kunugi

  PSYCHOPHARMACOLOGY SPRINGER 219 (4) 1099 - 1109 0033-3158 2012/02 [Refereed]
  
• More severe impairment of manual dexterity in bipolar disorder compared to unipolar major depression

  Daimei Sasayama; Hiroaki Hori; Toshiya Teraishi; Kotaro Hattori; Miho Ota; Junko Matsuo; Yumiko Kawamoto; Yukiko Kinoshita; Miyako Hashikura; Naoji Amano; Teruhiko Higuchi; Hiroshi Kunugi

  JOURNAL OF AFFECTIVE DISORDERS ELSEVIER SCIENCE BV 136 (3) 1047 - 1052 0165-0327 2012/02 [Refereed]
  
• Relationships between season of birth, schizotypy, temperament, character and neurocognition in a non-clinical population

  Hiroaki Hori; Toshiya Teraishi; Daimei Sasayama; Junko Matsuo; Yumiko Kawamoto; Yukiko Kinoshita; Hiroshi Kunugi

  PSYCHIATRY RESEARCH ELSEVIER IRELAND LTD 195 (1-2) 69 - 75 0165-1781 2012/01 [Refereed]
  
• Blood CADPS2 Delta Exon3 expression is associated with intelligence and memory in healthy adults

  Kotaro Hattori; Haruko Tanaka; Noriko Yamamoto; Toshiya Teraishi; Hiroaki Hori; Yukiko Kinoshita; Junko Matsuo; Yumiko Kawamoto; Hiroshi Kunugi

  BIOLOGICAL PSYCHOLOGY ELSEVIER SCIENCE BV 89 (1) 117 - 122 0301-0511 2012/01 [Refereed]
  
• Association of SNPs linked to increased expression of SLC1A1 with schizophrenia

  Yasue Horiuchi; Syuhei Iida; Minori Koga; Hiroki Ishiguro; Yoshimi Iijima; Toshiya Inada; Yuichiro Watanabe; Toshiyuki Someya; Hiroshi Ujike; Nakao Iwata; Norio Ozaki; Hiroshi Kunugi; Mamoru Tochigi; Masanari Itokawa; Makoto Arai; Kazuhiro Niizato; Shuji Iritani; Akiyoshi Kakita; Hitoshi Takahashi; Hiroyuki Nawa; Tadao Arinami

  American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics 1 159 (1) 30 - 37 1552-4841 2012/01 [Refereed]
  
• Further evidence for a male-selective genetic association of synapse-associated protein 97 (SAP97) gene with schizophrenia

  Akihito Uezato; Junko Kimura-Sato; Naoki Yamamoto; Yoshimi Iijima; Hiroshi Kunugi; Toru Nishikawa

  BEHAVIORAL AND BRAIN FUNCTIONS BIOMED CENTRAL LTD 8 2  1744-9081 2012/01 [Refereed]
  
• The efficacy of pramipexole, a dopamine receptor agonist, as an adjunctive treatment in treatment-resistant depression: an open-label trial.

  Hori H; Kunugi H

  TheScientificWorldJournal 2012 372474  2356-6140 2012 [Refereed]
  
• Elevated cortisol level and cortisol/DHEAS ratio in schizophrenia as revealed by low-dose dexamethasone suppression test

  Hiroaki Hori; Toshiya Teraishi; Daimei Sasayama; Takashi Fujii; Kotaro Hattori; Masanori Ishikawa; Hiroshi Kunugi

  Open Neuropsychopharmacology Journal 5 (1) 18 - 28 1876-5238 2012 [Refereed]
  
• The Efficacy of Pramipexole, a Dopamine Receptor Agonist, as an Adjunctive Treatment in Treatment-Resistant Depression: An Open-Label Trial

  Hiroaki Hori; Hiroshi Kunugi

  SCIENTIFIC WORLD JOURNAL HINDAWI PUBLISHING CORPORATION 1537-744X 2012 [Refereed]
  
• Association of SNPs linked to increased expression of SLC1A1 with schizophrenia.

  Horiuchi Yasue; Iida Syuhei; Koga Minori; Ishiguro Hiroki; Iijima Yoshimi; Inada Toshiya; Watanabe Yuichiro; Someya Toshiyuki; Ujike Hiroshi; Iwata Nakao; Ozaki Norio; Kunugi Hiroshi; Tochigi Mamoru; Itokawa Masanari; Arai Makoto; Niizato Kazuhiro; Iritani Shuji; Kakita Akiyoshi; Takahashi Hitoshi; Nawa Hiroyuki; Arinami Tadao

  Am J Med Genet B Neuropsychiatr Genet 159B (1) 30 - 37 1552-485X 2012/01 [Refereed]
  
• A polymorphism of the ABCA1 gene confers susceptibility to schizophrenia and related brain changes

  Miho Ota; Takashi Fujii; Kiyotaka Nemoto; Masahiko Tatsumi; Yoshiya Moriguchi; Ryota Hashimoto; Noriko Sato; Nakao Iwata; Hiroshi Kunugi

  PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY PERGAMON-ELSEVIER SCIENCE LTD 35 (8) 1877 - 1883 0278-5846 2011/12 [Refereed]
  
• Positive Association of Phencyclidine-Responsive Genes, PDE4A and PLAT, With Schizophrenia

  Xiangdong Deng; Hiromi Takaki; Lixiang Wang; Tosihide Kuroki; Tatsuo Nakahara; Kijiro Hashimoto; Hideaki Ninomiya; Tadao Arinami; Toshiya Inada; Hiroshi Ujike; Masanari Itokawa; Mamoru Tochigi; Yuichiro Watanabe; Toshiyuki Someya; Hiroshi Kunugi; Nakao Iwata; Norio Ozaki; Hiroki Shibata; Yasuyuki Fukumaki

  AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS WILEY-BLACKWELL 156B (7) 850 - 858 1552-4841 2011/12 [Refereed]
  
• Support for association between the Ser205Leu polymorphism of p75(NTR) and major depressive disorder

  Takashi Fujii; Noriko Yamamoto; Hiroaki Hori; Kotaro Hattori; Daimei Sasayama; Toshiya Teraishi; Miyako Hashikura; Masahiko Tatsumi; Nagahisa Okamoto; Teruhiko Higuchi; Hiroshi Kunugi

  JOURNAL OF HUMAN GENETICS NATURE PUBLISHING GROUP 56 (11) 806 - 809 1434-5161 2011/11 [Refereed]
  
• Growth factors stimulate expression of neuronal and glial miR-132

  Tadahiro Numakawa; Noriko Yamamoto; Shuichi Chiba; Misty Richards; Yoshiko Ooshima; Soichiro Kishi; Kazuo Hashido; Naoki Adachi; Hiroshi Kunugi

  NEUROSCIENCE LETTERS ELSEVIER IRELAND LTD 505 (3) 242 - 247 0304-3940 2011/11 [Refereed]
  
• Association of plasma IL-6 and soluble IL-6 receptor levels with the Asp358Ala polymorphism of the IL-6 receptor gene in schizophrenic patients

  Daimei Sasayama; Chisato Wakabayashi; Hiroaki Hori; Toshiya Teraishi; Kotaro Hattori; Miho Ota; Masanori Ishikawa; Kunimasa Arima; Teruhiko Higuchi; Naoji Amano; Hiroshi Kunugi

  JOURNAL OF PSYCHIATRIC RESEARCH PERGAMON-ELSEVIER SCIENCE LTD 45 (11) 1439 - 1444 0022-3956 2011/11 [Refereed]
  
• Glucocorticoid suppresses BDNF-stimulated MAPK/ERK pathway via inhibiting interaction of Shp2 with TrkB

  Emi Kumamaru; Tadahiro Numakawa; Naoki Adachi; Hiroshi Kunugi

  FEBS LETTERS ELSEVIER SCIENCE BV 585 (20) 3224 - 3228 0014-5793 2011/10 [Refereed]
  
• うつ病患者の栄養学的検討

  功刀 浩; 古賀 賀恵; 佐々木 敏; 堀 弘明; 服部 功太郎

  New Diet Therapy (一社)日本臨床栄養協会 27 (2) 121 - 121 0910-7258 2011/10
• うつ病の最先端脳科学的研究とその臨床応用 視床下部-下垂体-副腎系とうつ病 最近の知見

  功刀 浩; 堀 弘明; 沼川 忠広

  日本臨床精神神経薬理学会・日本神経精神薬理学会合同年会プログラム・抄録集 日本臨床精神神経薬理学会・日本神経精神薬理学会 21回・41回 108 - 108 2011/10
• MicroRNA function and neurotrophin BDNF

  Tadahiro Numakawa; Misty Richards; Naoki Adachi; Soichiro Kishi; Hiroshi Kunugi; Kazuo Hashido

  NEUROCHEMISTRY INTERNATIONAL PERGAMON-ELSEVIER SCIENCE LTD 59 (5) 551 - 558 0197-0186 2011/10 [Refereed]
  
• AGE-DEPENDENT REGULATION OF DEPRESSION-LIKE BEHAVIORS THROUGH MODULATION OF ADRENERGIC RECEPTOR alpha(1A) SUBTYPE EXPRESSION REVEALED BY THE ANALYSIS OF INTERLEUKIN-1 RECEPTOR ANTAGONIST KNOCKOUT MICE

  C. Wakabayashi; Y. Kiyama; H. Kunugi; T. Manabe; Y. Iwakura

  NEUROSCIENCE PERGAMON-ELSEVIER SCIENCE LTD 192 475 - 484 0306-4522 2011/09 [Refereed]
  
• Poor sleep is associated with exaggerated cortisol response to the combined dexamethasone/CRH test in a non-clinical population

  Hiroaki Hori; Toshiya Teraishi; Daimei Sasayama; Yuji Ozeki; Junko Matsuo; Yumiko Kawamoto; Yukiko Kinoshita; Kotaro Hattori; Teruhiko Higuchi; Hiroshi Kunugi

  JOURNAL OF PSYCHIATRIC RESEARCH PERGAMON-ELSEVIER SCIENCE LTD 45 (9) 1257 - 1263 0022-3956 2011/09 [Refereed]
  
• Possible association between Interleukin-1beta gene and schizophrenia in a Japanese population

  Daimei Sasayama; Hiroaki Hori; Toshiya Teraishi; Kotaro Hattori; Miho Ota; Yoshimi Iijima; Masahiko Tatsumi; Teruhiko Higuchi; Naoji Amano; Hiroshi Kunugi

  BEHAVIORAL AND BRAIN FUNCTIONS BIOMED CENTRAL LTD 7 35  1744-9081 2011/08 [Refereed]
  
• Difference in Temperament and Character Inventory scores between depressed patients with bipolar II and unipolar major depressive disorders

  Daimei Sasayama; Hiroaki Hon; Toshiya Teraishi; Kotaro Hattori; Miho Ota; Junko Matsuo; Yumiko Kawamoto; Yukiko Kinoshita; Miyako Hashikura; Norie Koga; Nagahisa Okamoto; Kota Sakamoto; Teruhiko Higuchi; Naoji Amano; Hiroshi Kunugi

  JOURNAL OF AFFECTIVE DISORDERS ELSEVIER SCIENCE BV 132 (3) 319 - 324 0165-0327 2011/08 [Refereed]
  
• Variants of the RELA Gene are Associated with Schizophrenia and their Startle Responses

  Ryota Hashimoto; Kazutaka Ohi; Yuka Yasuda; Motoyuki Fukumoto; Hidenaga Yamamori; Hidetoshi Takahashi; Masao Iwase; Tomo Okochi; Hiroaki Kazui; Osamu Saitoh; Masahiko Tatsumi; Nakao Iwata; Norio Ozaki; Kunitoshi Kamijima; Hiroshi Kunugi; Masatoshi Takeda

  NEUROPSYCHOPHARMACOLOGY NATURE PUBLISHING GROUP 36 (9) 1921 - 1931 0893-133X 2011/08 [Refereed]
  
• Expression of Ca2+-dependent activator protein for secretion 2 is increased in the brains of schizophrenic patients

  Kotaro Hattori; Haruko Tanaka; Chisato Wakabayashi; Noriko Yamamoto; Hirofumi Uchiyama; Toshiya Teraishi; Hiroaki Hori; Kunimasa Arima; Hiroshi Kunugi

  PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY PERGAMON-ELSEVIER SCIENCE LTD 35 (7) 1738 - 1743 0278-5846 2011/08 [Refereed]
  
• Association of interleukin-1 beta genetic polymorphisms with cognitive performance in elderly females without dementia

  Daimei Sasayama; Hiroaki Hori; Toshiya Teraishi; Kotaro Hattori; Miho Ota; Junko Matsuo; Yumiko Kawamoto; Yukiko Kinoshita; Teruhiko Higuchi; Naoji Amano; Hiroshi Kunugi

  JOURNAL OF HUMAN GENETICS NATURE PUBLISHING GROUP 56 (8) 613 - 616 1434-5161 2011/08 [Refereed]
  
• Modulation of cortisol responses to the DEX/CRH test by polymorphisms of the interleukin-1beta gene in healthy adults

  Daimei Sasayama; Hiroaki Hori; Yoshimi Iijima; Toshiya Teraishi; Kotaro Hattori; Miho Ota; Takashi Fujii; Teruhiko Higuchi; Naoji Amano; Hiroshi Kunugi

  BEHAVIORAL AND BRAIN FUNCTIONS BIOMED CENTRAL LTD 7 23  1744-9081 2011/07 [Refereed]
  
• SIRT1 gene, schizophrenia and bipolar disorder in the Japanese population: an association study

  T. Kishi; Y. Fukuo; T. Kitajima; T. Okochi; Y. Yamanouchi; Y. Kinoshita; K. Kawashima; T. Inada; H. Kunugi; T. Kato; T. Yoshikawa; H. Ujike; N. Ozaki; N. Iwata

  GENES BRAIN AND BEHAVIOR WILEY-BLACKWELL 10 (3) 257 - 263 1601-1848 2011/04 [Refereed]
  
• Attitudes toward schizophrenia in the general population, psychiatric staff, physicians, and psychiatrists: A web-based survey in Japan

  Hiroaki Hori; Misty Richards; Yumiko Kawamoto; Hiroshi Kunugi

  PSYCHIATRY RESEARCH ELSEVIER IRELAND LTD 186 (2-3) 183 - 189 0165-1781 2011/04 [Refereed]
  
• Association of ANK3 With Bipolar Disorder Confirmed in East Asia

  Atsushi Takata; Se Hyun Kim; Norio Ozaki; Nakao Iwata; Hiroshi Kunugi; Toshiya Inada; Hiroshi Ujike; Kazuhiko Nakamura; Norio Mori; Yong Min Ahn; Eun-Jeong Joo; Joo Yun Song; Shigenobu Kanba; Takeo Yoshikawa; Yong Sik Kim; Tadafumi Kato

  AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS WILEY-BLACKWELL 156B (3) 312 - 315 1552-4841 2011/04 [Refereed]
  
• Fynチロシンキナーゼを用いた統合失調症バイオマーカーの開発

  服部 功太郎; 田中 治子; 若林 千里; 内山 博文; 山本 宜子; 堀 弘明; 寺石 俊也; 有馬 邦正; 功刀 浩

  精神薬療研究年報 (公財)先進医薬研究振興財団 (43) 79 - 80 1346-1702 2011/03
• POLYMORPHISMS OF THE INTERLEUKIN-6 RECEPTOR GENE AND PLASMA LEVELS OF INTERLEUKIN-6 AND SOLUBLE INTERLEUKIN-6 RECEPTOR IN SCHIZOPHRENIA

  Sasayama, Daimei; Wakabayashi, Chisato; Iijima, Yoshimi; Fujii, Takashi; Tatsumi, Masahiko; Kunugi, Hiroshi

  SCHIZOPHRENIA BULLETIN OXFORD UNIV PRESS 37 (Suppl. 1) 77 - 77 0586-7614 2011/03
• A novel balanced chromosomal translocation found in subjects with schizophrenia and schizotypal personality disorder: Altered L-serine level associated with disruption of PSAT1 gene expression

  Yuji Ozeki; Benjamin S. Pickard; Shin-ichi Kano; Mary P. Malloy; Mariela Zeledon; Daniel Q. Sun; Kumiko Fujii; Keiko Wakui; Yukihiko Shirayama; Yoshimitsu Fukushima; Hiroshi Kunugi; Kenji Hashimoto; Walter J. Muir; Douglas H. Blackwood; Akira Sawa

  NEUROSCIENCE RESEARCH ELSEVIER IRELAND LTD 69 (2) 154 - 160 0168-0102 2011/02 [Refereed]
  
• Protective action of neurotrophic factors and estrogen against oxidative stress-mediated neurodegeneration

  Tadahiro Numakawa; Tomoya Matsumoto; Yumiko Numakawa; Misty Richards; Shigeto Yamawaki; Hiroshi Kunugi

  Journal of Toxicology 2011 405194  1687-8191 2011 [Refereed]
  
• The CLOCK Gene and Mood Disorders: A Case-Control Study and Meta-analysis

  Taro Kishi; Reiji Yoshimura; Yasuhisa Fukuo; Tsuyoshi Kitajima; Tomo Okochi; Shinji Matsunaga; Toshiya Inada; Hiroshi Kunugi; Tadafumi Kato; Takeo Yoshikawa; Hiroshi Ujike; Wakako Umene-Nakano; Jun Nakamura; Norio Ozaki; Alessandro Serretti; Christoph U. Correll; Nakao Iwata

  CHRONOBIOLOGY INTERNATIONAL INFORMA HEALTHCARE 28 (9) 825 - 833 0742-0528 2011 [Refereed]
  
• Reduction in BDNF-induced neurotransmitter release in cultured cortical neurons from intrauterine growth retardation rats

  Yoshiko Ooshima; Tadahiro Numakawa; Shuichi Chiba; Miyako Furuta; Naoki Adachi; Hiroshi Kunugi

  NEUROSCIENCE RESEARCH ELSEVIER IRELAND LTD 71 E136 - E137 0168-0102 2011 [Refereed]
  
• Possible involvement of BDNF dysfunction in the synaptic loss caused by phencyclidine

  Naoki Adachi; Tadahiro Numakawa; Emi Kumamaru; Chiaki Itami; Shuichi Chiba; Yoshimi Iijima; Misty Richards; Ritsuko Katoh-Semba; Hiroshi Kunugi

  NEUROSCIENCE RESEARCH ELSEVIER IRELAND LTD 71 E105 - E105 0168-0102 2011 [Refereed]
  
• Preventive effect by growth factors in suppression in neurotransmitter release after chronic glucocorticoid

  Tadahiro Numakawa; Adachi Naoki; Shuichi Chiba; Yoshiko Ooshima; Kazuo Hashido; Hiroshi Kunugi

  NEUROSCIENCE RESEARCH ELSEVIER IRELAND LTD 71 E136 - E136 0168-0102 2011 [Refereed]
  
• Brain-specific microRNA-132 induction by growth factors in cortical neurons

  Noriko Yamamoto; Tadahiro Numakawa; Naoki Adachi; Shuichi Chiba; Soichiro Kishi; Kazuo Hashido; Hiroshi Kunugi

  NEUROSCIENCE RESEARCH ELSEVIER IRELAND LTD 71 E136 - E136 0168-0102 2011 [Refereed]
  
• BDNF- and estrogen receptor alpha-mediated intracellular signaling in anxiety- and depression-like behaviors in postpartum rats

  Furuta Miyako; Numakawa Tadahiro; Chiba Shuichi; Ninomiya Midori; Kajiyama Yu; Funabashi Toshiya; Akema Tatsuo; Kunugi Hiroshi

  NEUROSCIENCE RESEARCH 71 E267  0168-0102 2011 [Refereed]
  
• Variants of the RELA gene are associated with schizophrenia and prepulse inhibition

  Hashimoto Ryota; Ohi Kazutaka; Yasuda Yuka; Fukumoto Motoyuki; Yamamori Hidenaga; Takahashi Hidetoshi; Iwase Masao; Okochi Tomo; Kazui Hiroaki; Saitoh Osamu; Tatsumi Masahiko; Iwata Nakao; Ozaki Norio; Kamijima Kunitoshi; Kunugi Hiroshi; Takeda Masatoshi

  NEUROSCIENCE RESEARCH 71 E395-E395  0168-0102 2011 [Refereed]
  
• Serotonin 1A receptor gene, schizophrenia and bipolar disorder: An association study and meta-analysis

  Taro Kishi; Tomo Okochi; Tomoko Tsunoka; Takenori Okumura; Tsuyoshi Kitajima; Kunihiro Kawashima; Yoshio Yamanouchi; Yoko Kinoshita; Hiroshi Naitoh; Toshiya Inada; Hiroshi Kunugi; Tadafumi Kato; Takeo Yoshikawa; Hiroshi Ujike; Norio Ozaki; Nakao Iwata

  PSYCHIATRY RESEARCH ELSEVIER IRELAND LTD 185 (1-2) 20 - 26 0165-1781 2011/01 [Refereed]
  
• Possible association of the semaphorin 3D gene (SEMA3D) with schizophrenia

  Takashi Fujii; Hirofumi Uchiyama; Noriko Yamamoto; Hiroaki Hori; Masahiko Tatsumi; Masanori Ishikawa; Kunimasa Arima; Teruhiko Higuchi; Hiroshi Kunugi

  JOURNAL OF PSYCHIATRIC RESEARCH PERGAMON-ELSEVIER SCIENCE LTD 45 (1) 47 - 53 0022-3956 2011/01 [Refereed]
  
• Schizotypal Personality in Healthy Adults Is Related to Blunted Cortisol Responses to the Combined Dexamethasone/Corticotropin-Releasing Hormone Test

  Hiroaki Hori; Toshiya Teraishi; Yuji Ozeki; Kotaro Hattori; Daimei Sasayama; Junko Matsuo; Yumiko Kawamoto; Yukiko Kinoshita; Teruhiko Higuchi; Hiroshi Kunugi

  NEUROPSYCHOBIOLOGY KARGER 63 (4) 232 - 241 0302-282X 2011 [Refereed]
  
• うつ病研究紹介 治療抵抗性うつ病に対するドパミン受容体作動薬の有用性に関する検討

  功刀 浩; 千葉 秀一; 堀 弘明; 沼川 忠広

  Depression Frontier (株)医薬ジャーナル社 8 (2) 85 - 90 1347-8893 2010/10
• Relationships between psychological distress, coping styles, and HPA axis reactivity in healthy adults

  Hiroaki Horia; Yuji Ozeki; Toshiya Teraishi; Junko Matsuo; Yumiko Kawamoto; Yukiko Kinoshita; Shiho Suto; Sumio Terada; Teruhiko Higuchi; Hiroshi Kunugi

  JOURNAL OF PSYCHIATRIC RESEARCH PERGAMON-ELSEVIER SCIENCE LTD 44 (14) 865 - 873 0022-3956 2010/10 [Refereed]
  
• Plasma levels of vascular endothelial growth factor and fibroblast growth factor 2 in patients with major depressive disorders

  M. Takebayashi; R. Hashimoto; K. Hisaoka; M. Tsuchioka; H. Kunugi

  JOURNAL OF NEURAL TRANSMISSION SPRINGER WIEN 117 (9) 1119 - 1122 0300-9564 2010/09 [Refereed]
  
• 治療抵抗性うつ病に対するドーパミン作動薬プラミペキソールのオープン臨床試験

  功刀 浩; 堀 弘明

  日本臨床精神神経薬理学会・日本神経精神薬理学会合同年会プログラム・抄録集 日本臨床精神神経薬理学会・日本神経精神薬理学会 20回・40回 140 - 140 2010/09
• An association study between the dymeclin gene and schizophrenia in the Japanese population

  Saori Yazaki; Minori Koga; Hiroki Ishiguro; Toshiya Inada; Hiroshi Ujike; Masanari Itokawa; Takeshi Otowa; Yuichiro Watanabe; Toshiyuki Someya; Nakao Iwata; Hiroshi Kunugi; Norio Ozaki; Tadao Arinami

  JOURNAL OF HUMAN GENETICS NATURE PUBLISHING GROUP 55 (9) 631 - 634 1434-5161 2010/09 [Refereed]
  
• 統合失調症とセマフォリン3D遺伝子(SEMA3D)の関連解析(Possible association of the semaphorin 3D gene (SEMA3D) with schizophrenia)

  藤井 崇; 内山 博文; 山本 典子; 堀 弘明; 巽 雅彦; 石川 正憲; 有馬 邦正; 樋口 輝彦; 功刀 浩

  神経化学 (一社)日本神経化学会 49 (2-3) 674 - 674 0037-3796 2010/08
• Cabergoline, a dopamine receptor agonist, has an antidepressant-like property and enhances brain-derived neurotrophic factor signaling

  Shuichi Chiba; Tadahiro Numakawa; Midori Ninomiya; Hyung Shin Yoon; Hiroshi Kunugi

  PSYCHOPHARMACOLOGY SPRINGER 211 (3) 291 - 301 0033-3158 2010/08 [Refereed]
  
• Supportive evidence for reduced expression of GNB1L in schizophrenia.

  Ishiguro Hiroki; Koga Minori; Horiuchi Yasue; Noguchi Emiko; Morikawa Miyuki; Suzuki Yoshimi; Arai Makoto; Niizato Kazuhiro; Iritani Shyuji; Itokawa Masanari; Inada Toshiya; Iwata Nakao; Ozaki Norio; Ujike Hiroshi; Kunugi Hiroshi; Sasaki Tsukasa; Takahashi Makoto; Watanabe Yuichiro; Someya Toshiyuki; Kakita Akiyoshi; Takahashi Hitoshi; Nawa Hiroyuki; Arinami Tadao

  Schizophr Bull 36 (4) 756 - 765 1745-1701 2010/07 [Refereed]
  
• Supportive Evidence for Reduced Expression of GNB1L in Schizophrenia

  Hiroki Ishiguro; Minori Koga; Yasue Horiuchi; Emiko Noguchi; Miyuki Morikawa; Yoshimi Suzuki; Makoto Arai; Kazuhiro Niizato; Shyuji Iritani; Masanari Itokawa; Toshiya Inada; Nakao Iwata; Norio Ozaki; Hiroshi Ujike; Hiroshi Kunugi; Tsukasa Sasaki; Makoto Takahashi; Yuichiro Watanabe; Toshiyuki Someya; Akiyoshi Kakita; Hitoshi Takahashi; Hiroyuki Nawa; Tadao Arinami

  SCHIZOPHRENIA BULLETIN OXFORD UNIV PRESS 36 (4) 756 - 765 0586-7614 2010/07 [Refereed]
  
• Serotonin 6 receptor gene and mood disorders: Case-control study and meta-analysis

  Yasuhisa Fukuo; Taro Kishi; Reiji Yoshimura; Tsuyoshi Kitajima; Tomo Okochi; Yoshio Yamanouchi; Yoko Kinoshita; Kunihiro Kawashima; Hiroshi Naitoh; Wakako Umene-Nakano; Toshiya Inada; Hiroshi Kunugi; Tadafumi Kato; Takeo Yoshikawa; Hiroshi Ujike; Jun Nakamura; Norio Ozaki; Nakao Iwata

  NEUROSCIENCE RESEARCH ELSEVIER IRELAND LTD 67 (3) 250 - 255 0168-0102 2010/07 [Refereed]
  
• Brain cannabinoid CB2 receptor in schizophrenia.

  Ishiguro Hiroki; Horiuchi Yasue; Ishikawa Maya; Koga Minori; Imai Keiko; Suzuki Yoshimi; Morikawa Miyuki; Inada Toshiya; Watanabe Yuichiro; Takahashi Makoto; Someya Toshiyuki; Ujike Hiroshi; Iwata Nakao; Ozaki Norio; Onaivi Emmanuel S; Kunugi Hiroshi; Sasaki Tsukasa; Itokawa Masanari; Arai Makoto; Niizato Kazuhiro; Iritani Shyuji; Naka Izumi; Ohashi Jun; Kakita Akiyoshi; Takahashi Hitoshi; Nawa Hiroyuki; Arinami Tadao

  Biol Psychiatry 67 (10) 974 - 982 1873-2402 2010/05 [Refereed]
  
• Brain Cannabinoid CB2 Receptor in Schizophrenia

  Hiroki Ishiguro; Yasue Horiuchi; Maya Ishikawa; Minori Koga; Keiko Imai; Yoshimi Suzuki; Miyuki Morikawa; Toshiya Inada; Yuichiro Watanabe; Makoto Takahashi; Toshiyuki Someya; Hiroshi Ujike; Nakao Iwata; Norio Ozaki; Emmanuel S. Onaivi; Hiroshi Kunugi; Tsukasa Sasaki; Masanari Itokawa; Makoto Arai; Kazuhiro Niizato; Shyuji Iritani; Izumi Naka; Jun Ohashi; Akiyoshi Kakita; Hitoshi Takahashi; Hiroyuki Nawa; Tadao Arinami

  BIOLOGICAL PSYCHIATRY ELSEVIER SCIENCE INC 67 (10) 974 - 982 0006-3223 2010/05 [Refereed]
  
• Failure to find an association between myosin heavy chain 9, non-muscle (MYH9) and schizophrenia: A three-stage case-control association study

  Hideki Amagane; Yuichiro Watanabe; Naoshi Kaneko; Ayako Nunokawa; Tatsuyuki Muratake; Hiroki Ishiguro; Tadao Arinami; Hiroshi Ujike; Toshiya Inada; Nakao Iwata; Hiroshi Kunugi; Tsukasa Sasaki; Ryota Hashimoto; Masanari Itokawa; Norio Ozaki; Toshiyuki Someya

  SCHIZOPHRENIA RESEARCH ELSEVIER SCIENCE BV 118 (1-3) 106 - 112 0920-9964 2010/05 [Refereed]
  
• Cortical neurons from intrauterine growth retardation rats exhibit lower response to neurotrophin BDNF

  Midori Ninomiya; Tadahiro Numakawa; Naoki Adachi; Miyako Furuta; Shuichi Chiba; Misty Richards; Shigenobu Shibata; Hiroshi Kunugi

  NEUROSCIENCE LETTERS ELSEVIER IRELAND LTD 476 (2) 104 - 109 0304-3940 2010/05 [Refereed]
  
• Functional interactions between steroid hormones and neurotrophin BDNF.

  Numakawa T; Yokomaku D; Richards M; Hori H; Adachi N; Kunugi H

  World journal of biological chemistry 5 1 (5) 133 - 143 2010/05 [Refereed]
  
• 【ニューロペプチド】ストレス反応・うつ病とニューロペプチド

  堀 弘明; 功刀 浩

  HORMONE FRONTIER IN GYNECOLOGY (株)メディカルレビュー社 17 (1) 31 - 37 1340-220X 2010/03
• A genetic variation in the dysbindin gene (DTNBP1) is associated with memory performance in healthy controls

  Ryota Hashimoto; Hiroko Noguchi; Hiroaki Hori; Tetsuo Nakabayashi; Tatsuyo Suzuki; Nakao Iwata; Norio Ozaki; Asako Kosuga; Masahiko Tatsumi; Kunitoshi Kamijima; Seiichi Harada; Masatoshi Takeda; Osamu Saitoh; Hiroshi Kunugi

  WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY TAYLOR & FRANCIS LTD 11 (2) 431 - 438 1562-2975 2010/03 [Refereed]
  
• Association Analyses Between Brain-Expressed Fatty-Acid Binding Protein (FABP) Genes and Schizophrenia and Bipolar Disorder

  Yoshimi Iwayama; Eiji Hattori; Motoko Maekawa; Kazuo Yamada; Tomoko Toyota; Tetsuo Ohnishi; Yasuhide Iwata; Kenji J. Tsuchiya; Genichi Sugihara; Mitsuru Kikuchi; Kenji Hashimoto; Masaomi Iyo; Toshiya Inada; Hiroshi Kunugi; Norio Ozaki; Nakao Iwata; Shinichiro Nanko; Kazuya Iwamoto; Yuji Okazaki; Tadafumi Kato; Takeo Yoshikawa

  AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS WILEY-LISS 153B (2) 484 - 493 1552-4841 2010/03 [Refereed]
  
• QTc prolongation and antipsychotic medications in a sample of 1017 patients with schizophrenia

  Yuji Ozeki; Kumiko Fujii; Naoki Kurimoto; Naoto Yamada; Masako Okawa; Takesuke Aoki; Jun Takahashi; Nobuya Ishida; Minoru Horie; Hiroshi Kunugi

  PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY PERGAMON-ELSEVIER SCIENCE LTD 34 (2) 401 - 405 0278-5846 2010/03 [Refereed]
  
• Association study of ubiquitin-specific peptidase 46 (USP46) with bipolar disorder and schizophrenia in a Japanese population

  Itaru Kushima; Branko Aleksic; Yoshihito Ito; Yukako Nakamura; Kazuhiko Nakamura; Norio Mori; Mitsuru Kikuchi; Toshiya Inada; Hiroshi Kunugi; Shinichiro Nanko; Tadafumi Kato; Takeo Yoshikawa; Hiroshi Ujike; Michio Suzuki; Nakao Iwata; Norio Ozaki

  JOURNAL OF HUMAN GENETICS NATURE PUBLISHING GROUP 55 (3) 133 - 136 1434-5161 2010/03 [Refereed]
  
• GLUCOCORTICOID ATTENUATES BRAIN-DERIVED NEUROTROPHIC FACTOR-DEPENDENT UPREGULATION OF GLUTAMATE RECEPTORS VIA THE SUPPRESSION OF MICRORNA-132 EXPRESSION

  H. Kawashima; T. Numakawa; E. Kumamaru; N. Adachi; H. Mizuno; M. Ninomiya; H. Kunugi; K. Hashido

  NEUROSCIENCE PERGAMON-ELSEVIER SCIENCE LTD 165 (4) 1301 - 1311 0306-4522 2010/02 [Refereed]
  
• Leukemia inhibitory factor gene is associated with schizophrenia and working memory function

  Yuko Okahisa; Hiroshi Ujike; Hiroshi Kunugi; Takeshi Ishihara; Masafumi Kodama; Manabu Takaki; Tatsuya Kotaka; Shigetoshi Kuroda

  PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY PERGAMON-ELSEVIER SCIENCE LTD 34 (1) 172 - 176 0278-5846 2010/02 [Refereed]
  
• Prednisolone causes anxiety- and depression-like behaviors and altered expression of apoptotic genes in mice hippocampus

  Yu Kajiyama; Yoshimi Iijima; Shuichi Chiba; Miyako Furuta; Midori Ninomiya; Aiko Izumi; Shigenobu Shibata; Hiroshi Kunugi

  PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY PERGAMON-ELSEVIER SCIENCE LTD 34 (1) 159 - 165 0278-5846 2010/02 [Refereed]
  
• BDNF function and intracellular signaling in neurons

  Tadahiro Numakawa; Shingo Suzuki; Emi Kumamaru; Naoki Adachi; Misty Richards; Hiroshi Kunugi

  HISTOLOGY AND HISTOPATHOLOGY F HERNANDEZ 25 (2) 237 - 258 0213-3911 2010/02 [Refereed]
  
• Cyclophosphamide promotes cell survival via activation of intracellular signaling in cultured cortical neurons

  Hiromi Kitazawa; Tadahiro Numakawa; Naoki Adachi; Emi Kumamaru; Tuerhong Tuerxun; Motoshige Kudo; Hiroshi Kunugi

  NEUROSCIENCE LETTERS ELSEVIER IRELAND LTD 470 (2) 139 - 144 0304-3940 2010/02 [Refereed]
  
• Antidepressant- and anxiolytic-like properties of dopamine receptor agonist cabergoline

  Shuichi Chiba; Tadahiro Numakawa; Midori Ninomiya; Hiroshi Kunugi

  NEUROSCIENCE RESEARCH ELSEVIER IRELAND LTD 68 E428 - E428 0168-0102 2010 [Refereed]
  
• Cultured neurons from intrauterine growth retardation rats display lower response to brain-derived neurotrophic factors

  Midori Ninomiya; Tadahiro Numakawa; Naoki Adachi; Miyako Furuta; Shuichi Chiba; Misty Richards; Shigenobu Shibata; Hiroshi Kunugi

  NEUROSCIENCE RESEARCH ELSEVIER IRELAND LTD 68 E258 - E258 0168-0102 2010 [Refereed]
  
• Possible changes in neurotrophin signalings and levels of ER alpha are involved in anxiety- and depressive- like behaviors in postpartum rats after weaning

  Furuta Miyako; Numakawa Tadahiro; Ninomiya Midori; Chiba Shuichi; Kajiyama Yu; Shibata Shigenobu; Funabashi Toshiya; Akema Tatsuo; Kunugi Hiroshi

  NEUROSCIENCE RESEARCH 68 E285  0168-0102 2010 [Refereed]
  
• Sexually Dimorphic Effect of the Val66Met Polymorphism of BDNF on Susceptibility to Alzheimer's Disease: New Data and Meta-Analysis

  Noriko Fukumoto; Takashi Fujii; Onofre Combarros; M. Ilyas Kamboh; Shin-Jen Tsai; Sachio Matsushita; Benedetta Nacmias; David E. Comings; Humberto Arboleda; Martin Ingelsson; Bradley T. Hyman; Hiroyasu Akatsu; Andrew Grupe; Agnes Lumi Nishimura; Mayana Zatz; Kari M. Mattila; Juha Rinne; Yu-ichi Goto; Takashi Asada; Shun Nakamura; Hiroshi Kunugi

  AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS WILEY-BLACKWELL 153B (1) 235 - 242 1552-4841 2010/01 [Refereed]
  
• The dopamine D3 receptor (DRD3) gene and risk of schizophrenia: Case-control studies and an updated meta-analysis

  Ayako Nunokawa; Yuichiro Watanabe; Naoshi Kaneko; Takuro Sugai; Saori Yazaki; Tadao Arinami; Hiroshi Ujike; Toshiya Inada; Nakao Iwata; Hiroshi Kunugi; Tsukasa Sasaki; Masanari Itokawa; Norio Ozaki; Ryota Hashimoto; Toshiyuki Someya

  SCHIZOPHRENIA RESEARCH ELSEVIER SCIENCE BV 116 (1) 61 - 67 0920-9964 2010/01 [Refereed]
  
• Possible association between the pituitary adenylate cyclase-activating polypeptide (PACAP) gene and major depressive disorder

  Ryota Hashimoto; Hitoshi Hashimoto; Norihito Shintani; Kazutaka Ohi; Hiroaki Hori; Osamu Saitoh; Asako Kosuga; Masahiko Tatsumi; Nakao Iwata; Norio Ozaki; Kunitoshi Kamijima; Akemichi Baba; Masatoshi Takeda; Hiroshi Kunugi

  NEUROSCIENCE LETTERS ELSEVIER IRELAND LTD 468 (3) 300 - 302 0304-3940 2010/01 [Refereed]
  
• SA4503, a sigma-1 receptor agonist, prevents cultured cortical neurons from oxidative stress-induced cell death via suppression of MAPK pathway activation and glutamate receptor expression

  Tuerhong Tuerxun; Tadahiro Numakawa; Naoki Adachi; Emi Kumamaru; Hiromi Kitazawa; Motoshige Kudo; Hiroshi Kunugi

  NEUROSCIENCE LETTERS ELSEVIER IRELAND LTD 469 (3) 303 - 308 0304-3940 2010/01 [Refereed]
  
• Possible interaction between glucocorticoid and BDNF function

  Tadahiro Numakawa; Hiroshi Kunugi

  Seikagaku 5 82 (5) 419 - 422 0037-1017 2010 [Refereed]
  
• Interface between hypothalamic-pituitary-adrenal axis and brain-derived neurotrophic factor in depression

  Hiroshi Kunugi; Hiroaki Hori; Naoki Adachi; Tadahiro Numakawa

  PSYCHIATRY AND CLINICAL NEUROSCIENCES WILEY 64 (5) 447 - 459 1323-1316 2010 [Refereed]
  
• Preliminary Genome-Wide Association Study of Bipolar Disorder in the Japanese Population

  Eiji Hattori; Tomoko Toyota; Yuichi Ishitsuka; Yoshimi Iwayama; Kazuo Yamada; Hiroshi Ujike; Yukitaka Morita; Masafumi Kodama; Kenji Nakata; Yoshio Minabe; Kazuhiko Nakamura; Yasuhide Iwata; Nori Takei; Norio Mori; Hiroshi Naitoh; Yoshio Yamanouchi; Nakao Iwata; Norio Ozaki; Tadafumi Kato; Toru Nishikawa; Atsushi Kashiwa; Mika Suzuki; Kunihiko Shioe; Manabu Shinohara; Masami Hirano; Shinichiro Nanko; Akihisa Akahane; Mikako Ueno; Naoshi Kaneko; Yuichiro Watanabe; Toshiyuki Someya; Kenji Hashimoto; Masaomi Iyo; Masanari Itokawa; Makoto Arai; Masahiro Nankai; Toshiya Inada; Sumiko Yoshida; Hiroshi Kunugi; Michiko Nakamura; Yoshimi Iijima; Yuji Okazaki; Teruhiko Higuchi; Takeo Yoshikawa

  AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS WILEY-BLACKWELL 150B (8) 1110 - 1117 1552-4841 2009/12 [Refereed]
  
• Association analysis between schizophrenia and the AP-3 complex genes

  Ryota Hashimoto; Kazutaka Ohi; Takeya Okada; Yuka Yasuda; Hidenaga Yamamori; Hiroaki Hori; Takao Hikita; Shinichiro Taya; Osamu Saitoh; Asako Kosuga; Masahiko Tatsumi; Kunitoshi Kamijima; Kozo Kaibuchi; Masatoshi Takeda; Hiroshi Kunugi

  NEUROSCIENCE RESEARCH ELSEVIER IRELAND LTD 65 (1) 113 - 115 0168-0102 2009/09 [Refereed]
  
• No association between the Bcl2-interacting killer (BIK) gene and schizophrenia

  Kazutaka Ohi; Ryota Hashimoto; Yuka Yasuda; Hidenaga Yamamori; Hiroaki Hori; Osamu Saitoh; Masahiko Tatsumi; Masatoshi Takeda; Nakao Iwata; Norio Ozaki; Kunitoshi Kamijima; Hiroshi Kunugi

  NEUROSCIENCE LETTERS ELSEVIER IRELAND LTD 463 (1) 60 - 63 0304-3940 2009/09 [Refereed]
  
• Involvement of SMARCA2/BRM in the SWI/SNF chromatin-remodeling complex in schizophrenia.

  Koga Minori; Ishiguro Hiroki; Yazaki Saori; Horiuchi Yasue; Arai Makoto; Niizato Kazuhiro; Iritani Shuji; Itokawa Masanari; Inada Toshiya; Iwata Nakao; Ozaki Norio; Ujike Hiroshi; Kunugi Hiroshi; Sasaki Tsukasa; Takahashi Makoto; Watanabe Yuichiro; Someya Toshiyuki; Kakita Akiyoshi; Takahashi Hitoshi; Nawa Hiroyuki; Muchardt Christian; Yaniv Moshe; Arinami Tadao

  Hum Mol Genet 18 (13) 2483 - 2494 1460-2083 2009/07 [Refereed]
  
• Involvement of SMARCA2/BRM in the SWI/SNF chromatin-remodeling complex in schizophrenia

  Minori Koga; Hiroki Ishiguro; Saori Yazaki; Yasue Horiuchi; Makoto Arai; Kazuhiro Niizato; Shuji Iritani; Masanari Itokawa; Toshiya Inada; Nakao Iwata; Norio Ozaki; Hiroshi Ujike; Hiroshi Kunugi; Tsukasa Sasaki; Makoto Takahashi; Yuichiro Watanabe; Toshiyuki Someya; Akiyoshi Kakita; Hitoshi Takahashi; Hiroyuki Nawa; Christian Muchardt; Moshe Yaniv; Tadao Arinami

  HUMAN MOLECULAR GENETICS OXFORD UNIV PRESS 18 (13) 2483 - 2494 0964-6906 2009/07 [Refereed]
  
• BDNF is not associated with schizophrenia: Data from a Japanese population study and meta-analysis

  Kunihiro Kawashima; Masashi Ikeda; Taro Kishi; Tsuyoshi Kitajima; Yoshio Yamanouchi; Yoko Kinoshita; Tomo Okochi; Branko Aleksic; Makoto Tomita; Takeya Okada; Hiroshi Kunugi; Toshiya Inada; Norio Ozaki; Nakao Iwata

  SCHIZOPHRENIA RESEARCH ELSEVIER SCIENCE BV 112 (1-3) 72 - 79 0920-9964 2009/07 [Refereed]
  
• A two-stage case-control association study of PADI2 with schizophrenia

  Yuichiro Watanabe; Ayako Nunokawa; Naoshi Kaneko; Tadao Arinami; Hiroshi Ujike; Toshiya Inada; Nakao Iwata; Hiroshi Kunugi; Masanari Itokawa; Takeshi Otowa; Norio Ozaki; Toshiyuki Someya

  JOURNAL OF HUMAN GENETICS NATURE PUBLISHING GROUP 54 (7) 430 - 432 1434-5161 2009/07 [Refereed]
  
• Tumor necrosis factor receptor-associated protein 1 regulates cell adhesion and synaptic morphology via modulation of N-cadherin expression

  Kyoko Kubota; Kiyoshi Inoue; Ryota Hashimoto; Natsuko Kumamoto; Asako Kosuga; Masahiko Tatsumi; Kunitoshi Kamijima; Hiroshi Kunugi; Nakao Iwata; Norio Ozaki; Masatoshi Takeda; Masaya Tohyama

  JOURNAL OF NEUROCHEMISTRY WILEY-BLACKWELL PUBLISHING, INC 110 (2) 496 - 508 0022-3042 2009/07 [Refereed]
  
• Gene expression and association analyses of the phosphodiesterase 4B (PDE4B) gene in major depressive disorder in the Japanese population

  Shusuke Numata; Jun Ichi Iga; Masahito Nakataki; Shin'ya Tayoshi; Kyoko Taniguchi; Satsuki Sumitani; Masahito Tomotake; Toshihito Tanahashi; Mitsuo Itakura; Yoko Kamegaya; Masahiko Tatsumi; Akira Sano; Takashi Asada; Hiroshi Kunugi; Shu Ichi Ueno; Tetsuro Ohmori

  American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics 4 150 (4) 527 - 534 1552-4841 2009/06 [Refereed]
  
• Mitochondrial DNA Haplogroup Analysis in Patients With Bipolar Disorder

  An-a Kazuno; Kae Munakata; Kanako Mori; Shinichiro Nanko; Hiroshi Kunugi; Kazuhiko Nakamura; Norio Mori; Kazuo Yamada; Takeo Yoshikawa; Nobumasa Kato; Tadafumi Kato

  AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS WILEY-LISS 150B (2) 243 - 247 1552-4841 2009/03 [Refereed]
  
• Effect of the brain-derived neurotrophic factor and the apolipoprotein E polymorphisms on disease progression in preclinical Alzheimer's disease

  R. Hashimoto; Y. Hirata; T. Asada; F. Yamashita; K. Nemoto; T. Mori; Y. Moriguchi; H. Kunugi; K. Arima; T. Ohnishi

  GENES BRAIN AND BEHAVIOR WILEY-BLACKWELL PUBLISHING, INC 8 (1) 43 - 52 1601-1848 2009/02 [Refereed]
  
• Animal models for schizophrenia: A brief overview

  Miyako Furuta; Hiroshi Kunugi

  Biomarkers for Psychiatric Disorders Springer US 163 - 184 2009 [Refereed]
  
• Effect of BDNF and the ApoE polymorphisms on disease progression in preclinical Alzheimer’s disease.

  Hashimoto, R; Hirata, Y; Asada, T; Yamashita, F; Nemoto, K; Mori, T; Moriguchi, Y; Kunugi, H; Arima, K; Ohnishi, T

  Gene Brain Behav 8 43-52  2009/01 [Refereed]
  
• Sexually dimorphic effect of the Val66Met polymorphism of BDNF on susceptibility to Alzheimer's disease

  Fujii, Takashi; Fukumoto, Noriko; Goto, Yu-ichi; Asada, Takashi; Nakamura, Shun; Kunugi, Hiroshi

  NEUROSCIENCE RESEARCH ELSEVIER IRELAND LTD 65 (Suppl. 1) 0 - 0 0168-0102 2009/01 [Refereed]
  
• ANXIOLYTIC AND ANTIDEPRESSANT EFFECTS OF ESTROGEN THROUGH ESTROGEN RECEPTOR alpha, BUT NOT beta, IN POSTPARTUM RATS AFTER WEANING PUPS

  Furuta Miyako; Ninomiya Midori; Chiba Shuichi; Kajiyama Yu; Shibata Shigenobu; Akema Tatsuo; Kunugi Hiroshi

  JOURNAL OF PHYSIOLOGICAL SCIENCES 59 333  1880-6546 2009 [Refereed]
  
• Estrogen receptor alpha is involved in anxiety- and depressive-like behaviors in postpartum rats after weaning pups

  Furuta Miyako; Ninomiya Midori; Chiba Shuichi; Kajiyama Yu; Shibata Shigenobu; Akema Tatsuo; Kunugi Hiroshi

  NEUROSCIENCE RESEARCH 65 S221  0168-0102 2009 [Refereed]
  
• Glucocorticoid receptor interaction with TrkB promotes BDNF-triggered PLC-gamma signaling for glutamate release via a glutamate transporter

  Tadahiro Numakawa; Emi Kumamaru; Naoki Adachi; Yuki Yagasaki; Aiko Izumi; Hiroshi Kunugi

  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA NATL ACAD SCIENCES 106 (2) 647 - 652 0027-8424 2009/01 [Refereed]
  
• Two-stage case-control association study of polymorphisms in rheumatoid arthritis susceptibility genes with schizophrenia

  Yuichiro Watanabe; Ayako Nunokawa; Naoshi Kaneko; Tatsuyuki Muratake; Tadao Arinami; Hiroshi Ujike; Toshiya Inada; Nakao Iwata; Hiroshi Kunugi; Masanari Itokawa; Takeshi Otowa; Norio Ozaki; Toshiyuki Someya

  JOURNAL OF HUMAN GENETICS NATURE PUBLISHING GROUP 54 (1) 62 - 65 1434-5161 2009/01 [Refereed]
  
• Abnormal microstructures of the basal ganglia in schizophrenia revealed by diffusion tensor imaging

  Ryota Hashimoto; Takeyuki Mori; Kiyotaka Nemoto; Yoshiya Moriguchi; Hiroko Noguchi; Tetsuo Nakabayashi; Hiroaki Hori; Seiichi Harada; Hiroshi Kunugi; Osamu Saitoh; Takashi Ohnishi

  WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY TAYLOR & FRANCIS LTD 10 (1) 65 - 69 1562-2975 2009 [Refereed]
  
• Association between the dysbindin gene (DTNBP1) and cognitive functions in Japanese subjects

  Ryota Hashimoto; Hiroko Noguchi; Hiroaki Hori; Kazutaka Ohi; Yuka Yasuda; Masatoshi Takeda; Hiroshi Kunugi

  PSYCHIATRY AND CLINICAL NEUROSCIENCES WILEY-BLACKWELL PUBLISHING, INC 63 (4) 550 - 556 1323-1316 2009 [Refereed]
  
• p75NTR as a therapeutic target for neuropsychiatric diseases

  Takashi Fujii; Hiroshi Kunugi

  Current Molecular Pharmacology 1 2 (1) 70 - 76 1874-4672 2009 [Refereed]
  
• Genetic Variations of Human Neuropsin Gene and Psychiatric Disorders: Polymorphism Screening and Possible Association with Bipolar Disorder and Cognitive Functions

  Aiko Izumi; Yoshimi Iijima; Hiroko Noguchi; Tadahiro Numakawa; Takeya Okada; Hiroaki Hori; Tadafumi Kato; Masahiko Tatsumi; Asako Kosuga; Kunitoshi Kamijima; Takashi Asada; Kunimasa Arima; Osamu Saitoh; Sadao Shiosaka; Hiroshi Kunugi

  NEUROPSYCHOPHARMACOLOGY NATURE PUBLISHING GROUP 33 (13) 3237 - 3245 0893-133X 2008/12 [Refereed]
  
• Functional near-infrared spectroscopy reveals altered hemispheric laterality in relation to schizotypy during verbal fluency task

  Hiroaki Hori; Yuji Ozeki; Sumio Terada; Hiroshi KunUgi

  PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY PERGAMON-ELSEVIER SCIENCE LTD 32 (8) 1944 - 1951 0278-5846 2008/12 [Refereed]
  
• 【統合失調症の生物学的研究】統合失調症の神経生理学的研究

  堀 弘明; 功刀 浩

  Medical Science Digest (株)ニュー・サイエンス社 34 (13) 582 - 585 1347-4340 2008/11
• Schizotypal traits and cognitive function in healthy adults

  Hiroko Noguchi; Hiroaki Hori; Hiroshi Kunugi

  PSYCHIATRY RESEARCH ELSEVIER IRELAND LTD 161 (2) 162 - 169 0165-1781 2008/11 [Refereed]
  
• Microarray comparative genomic hybridization analysis of 59 patients with schizophrenia

  Takeshi Mizuguchi; Ryota Hashimoto; Masanari Itokawa; Akira Sano; Osamu Shimokawa; Yukiko Yoshimura; Naoki Harada; Noriko Miyake; Akira Nishimura; Hirotomo Saitsu; Nadiya Sosonkina; Norio Niikawa; Hiroshi Kunugi; Naomichi Matsumoto

  Journal of Human Genetics 10 53 (10) 914 - 919 1434-5161 2008/10 [Refereed]
  
• Replication study for associations between polymorphisms in the CLDN5 and DGCR2 genes in the 22q11 deletion syndrome region and schizophrenia

  Hiroki Ishiguro; Keiko Imai; Minori Koga; Yasue Horiuchi; Toshiya Inada; Nakao Iwata; Norio Ozaki; Hiroshi Ujike; Masanari Itokawa; Hiroshi Kunugi; Tsukasa Sasaki; Yuichiro Watanabe; Toshiyuki Someya; Tadao Arinami

  PSYCHIATRIC GENETICS LIPPINCOTT WILLIAMS & WILKINS 18 (5) 255 - 256 0955-8829 2008/10 [Refereed]
  
• Failure to confirm an association between Epsin 4 and schizophrenia in a Japanese population

  Misty Richards; Yoshimi Iijima; Tomoko Shizuno; Yoko Kamegaya; Hiroaki Hori; Mayu Omori; Kunimasa Arima; Osamu Saitoh; Hiroshi Kunugi

  JOURNAL OF NEURAL TRANSMISSION SPRINGER WIEN 115 (9) 1347 - 1354 0300-9564 2008/09 [Refereed]
  
• Dose-dependent effect of the Val66Met polymorphism of the brain-derived neurotrophic factor gene on memory-related hippocampal activity

  Ryota Hashimoto; Yoshiya Moriguchi; Fumio Yamashita; Takeyuki Mori; Kiyotaka Nemoto; Takeya Okada; Hiroaki Hori; Hiroko Noguchi; Hiroshi Kunugi; Takashi Ohnishi

  NEUROSCIENCE RESEARCH ELSEVIER IRELAND LTD 61 (4) 360 - 367 0168-0102 2008/08 [Refereed]
  
• Behavioral abnormalities and dopamine reductions in sdy mutant mice with a deletion in Dtnbp1, a susceptibility gene for schizophrenia

  Satoko Hattori; Tomotaka Murotani; Shinsuke Matsuzaki; Tomoko Ishizuka; Natsuko Kumamoto; Masatoshi Takeda; Masaya Tohyama; Atsushi Yamatodani; Hiroshi Kunugi; Ryota Hashimoto

  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS ACADEMIC PRESS INC ELSEVIER SCIENCE 373 (2) 298 - 302 0006-291X 2008/08 [Refereed]
  
• Personality in schizophrenia and character assessed with the temperament inventory (TCI)

  Hiroaki Hori; Hiroko Noguchi; Ryota Hashimoto; Tetsuo Nakabayashi; Osamu Saitoh; Robin M. Murray; Shigeo Okabe; Hiroshi Kunugi

  PSYCHIATRY RESEARCH ELSEVIER IRELAND LTD 160 (2) 175 - 183 0165-1781 2008/08 [Refereed]
  
• Impairment of motor dexterity in schizophrenia assessed by a novel finger movement test

  Akira Midorikawa; Ryota Hashimoto; Hiroko Noguchi; Osamu Saitoh; Hiroshi Kunugi; Katsuki Nakamura

  PSYCHIATRY RESEARCH ELSEVIER IRELAND LTD 159 (3) 281 - 289 0165-1781 2008/06 [Refereed]
  
• TGFBR2 gene expression and genetic association with schizophrenia

  Shusuke Numata; Shu-ichi Ueno; Jun-ichi Iga; Ken Yamauchi; Song Hongwei; Ryota Hashimoto; Masatoshi Takeda; Hiroshi Kunugi; Mitsuo Itakurla; Tetsuro Ohmori

  JOURNAL OF PSYCHIATRIC RESEARCH PERGAMON-ELSEVIER SCIENCE LTD 42 (6) 425 - 432 0022-3956 2008/05 [Refereed]
  
• A polymorphism of the metabotropic glutamate receptor mGluR7 (GRM7) gene is associated with schizophrenia

  Tsuyuka Ohtsuki; Minori Koga; Hiroki Ishiguro; Yasue Horiuchi; Makoto Arai; Kazuhiro Niizato; Masanari Itokawa; Toshiya Inada; Nakao Iwata; Shyuji Iritani; Norio Ozaki; Hiroshi Kunugi; Hiroshi Ujike; Yuichiro Watanabe; Toshiuki Someya; Tadao Arinami

  SCHIZOPHRENIA RESEARCH ELSEVIER SCIENCE BV 101 (1-3) 9 - 16 0920-9964 2008/04 [Refereed]
  
• Large-scale case-control study of a functional polymorphism in the glutamate receptor, metabotropic 3 gene in patients with schizophrenia

  Ayako Nunokawa; Yuichiro Watanabe; Hideaki Kitamura; Naoshi Kaneko; Tadao Arinami; Hiroshi Ujike; Toshiya Inada; Nakao Iwata; Hiroshi Kunugi; Masanari Itokawa; Norio Ozaki; Toshiyuki Someya

  PSYCHIATRY AND CLINICAL NEUROSCIENCES BLACKWELL PUBLISHING 62 (2) 239 - 240 1323-1316 2008/04 [Refereed]
  
• Glucocorticoid prevents brain-derived neurotrophic factor-mediated maturation of synaptic function in developing hippocampal neurons through reduction in the activity of mitogen-activated protein kinase

  Emi Kumamaru; Tadahiro Numakawa; Naoki Adachi; Yuki Yagasaki; Aiko Izumi; Madinyet Niyaz; Motoshige Kudo; Hiroshi Kunugi

  MOLECULAR ENDOCRINOLOGY ENDOCRINE SOC 22 (3) 546 - 558 0888-8809 2008/03 [Refereed]
  
• IQ decline and memory impairment in Japanese patients with chronic schizophrenia

  Hiroaki Hori; Hiroko Noguchi; Ryota Hashimoto; Shigeo Okabe; Osamu Saitoh; Hiroshi Kunugi

  PSYCHIATRY RESEARCH ELSEVIER IRELAND LTD 158 (2) 251 - 255 0165-1781 2008/03 [Refereed]
  
• The human neuropsin gene has a possible association with bipolar disorder and cognitive functions

  Izumi, Aiko; Iijima, Yoshimi; Noguchi, Hiroko; Numakawa, Tadahiro; Okada, Takeya; Hori, Hiroaki; Kato, Tadafumi; Tatsumi, Masahiko; Kosuga, Asako; Kamijima, Kunitoshi; Asada, Takashi; Arima, Kunimasa; Saitoh, Osamu; Shiosaka, Sadao; Kunugi, Hiroshi

  NEUROSCIENCE RESEARCH ELSEVIER IRELAND LTD 61 (Suppl. 1) 0 - 0 0168-0102 2008/01 [Refereed]
  
• A possible association between missense polymorphism of the breakpoint cluster region gene and lithium prophylaxis in bipolar disorder

  Takuya Masui; Ryota Hashimoto; Ichiro Kusumi; Katsuji Suzuki; Teruaki Tanaka; Shin Nakagawa; Tatsuyo Suzuki; Nakao Iwata; Norio Ozaki; Tadalunii Kato; Masatoshi Takeda; Hiroshi Kunugi; Tsukasa Koyama

  PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY PERGAMON-ELSEVIER SCIENCE LTD 32 (1) 204 - 208 0278-5846 2008/01 [Refereed]
  
• Schizotypal traits in healthy women predict prefrontal activation patterns during a verbal fluency task: A near-infrared spectroscopy study

  Hiroaki Hori; Mitsue Nagamine; Takahiro Soshi; Shigeo Okabe; Yoshiharu Kim; Hiroshi Kunugi

  NEUROPSYCHOBIOLOGY KARGER 57 (1-2) 61 - 69 0302-282X 2008 [Refereed]
  
• Pituitary adenylate cyclase-activating polypeptide is associated with schizophrenia

  R. Hashimoto; H. Hashimoto; N. Shintani; S. Chiba; S. Hattori; T. Okada; M. Nakajima; K. Tanaka; N. Kawagishi; K. Nemoto; T. Mori; T. Ohnishi; H. Noguchi; H. Hori; T. Suzuki; N. Iwata; N. Ozaki; T. Nakabayashi; O. Saitoh; A. Kosuga; M. Tatsumi; K. Kamijima; D. R. Weinberger; H. Kunugi; A. Baba

  MOLECULAR PSYCHIATRY NATURE PUBLISHING GROUP 12 (11) 1026 - 1032 1359-4184 2007/11 [Refereed]
  
• A possible association between the Val158Met polymorphism of the catechol-O-methyl transferase gene and the personality trait of harm avoidance in Japanese healthy subjects

  Ryota Hashimoto; Hiroko Noguchi; Hiroaki Hori; Kazutaka Ohi; Yuka Yasuda; Masatoshi Takeda; Hiroshi Kunugi

  NEUROSCIENCE LETTERS ELSEVIER IRELAND LTD 428 (1) 17 - 20 0304-3940 2007/11 [Refereed]
  
• MCI-186 prevents brain tissue from neuronal damage in cerebral infarction through the activation of intracellular signaling

  Madinyet Niyaz; Tadahiro Numakawa; Yoshinori Matsuki; Emi Kumamaru; Naoki Adachi; Hiromi Kitazawa; Hiroshi Kunugi; Motoshige Kudo

  JOURNAL OF NEUROSCIENCE RESEARCH WILEY-LISS 85 (13) 2933 - 2942 0360-4012 2007/10 [Refereed]
  
• Association analysis of HSP90B1 with bipolar disorder

  Chihiro Kakiuchi; Mizuho Ishiwata; Shinichiro Nanko; Hiroshi Kunugi; Yoshio Minabe; Kazuhiko Nakamura; Norio Mori; Kumiko Fujii; Tadashi Umekage; Mamoru Tochigi; Kazuhisa Kohda; Tsukasa Sasaki; Kazuo Yamada; Takeo Yoshikawa; Tadafumi Kato

  JOURNAL OF HUMAN GENETICS SPRINGER TOKYO 52 (10) 794 - 803 1434-5161 2007/10 [Refereed]
  
• Prepulse inhibition of acoustic startle in Japanese patients with chronic schizophrenia

  Hiroshi Kunugi; Miho Tanaka; Hiroaki Hori; Ryota Hashimoto; Osamu Saitoh; Naoyuki Hironaka

  NEUROSCIENCE RESEARCH ELSEVIER IRELAND LTD 59 (1) 23 - 28 0168-0102 2007/09 [Refereed]
  
• A promoter haplotype of the inositol monophosphatase 2 gene (IMPA2) at 18p11.2 confers a possible risk for bipolar disorder by enhancing transcription

  Tetsuo Ohnishi; Kazuo Yamada; Hisako Ohba; Yoshimi Iwayama; Tomoko Toyota; Eiji Hattori; Toshiya Inada; Hiroshi Kunugi; Masahiko Tatsumi; Norio Ozaki; Nakao Iwata; Kaoru Sakamoto; Yoshimi Iijima; Yasuhide Iwata; Kenji J. Tsuchiya; Genichi Sugihara; Shinichiro Nanko; Noriko Osumi; Sevilla D. Detera-Wadleigh; Tadafumi Kato; Takeo Yoshikawa

  NEUROPSYCHOPHARMACOLOGY NATURE PUBLISHING GROUP 32 (8) 1727 - 1737 0893-133X 2007/08 [Refereed]
  
• Epigenetic aberration of the human REELIN gene in psychiatric disorders

  Y. Tamura; H. Kunugi; J. Ohashi; H. Hohjoh

  MOLECULAR PSYCHIATRY NATURE PUBLISHING GROUP 12 (6) 593 - 600 1359-4184 2007/06 [Refereed]
  
• The possible association between epigenetic aberration in DNA methylation in RELN and psychiatric disorders

  Y. Tamura; H. Kunugi; J. Ohashi; H. Hohjoh

  Molecular Psychiatry 12 (6) 519  1359-4184 2007/06 [Refereed]
  
• Enriched environments influence depression-related behavior in adult mice and the survival of newborn cells in their hippocampi

  Satoko Hattori; Ryota Hashimoto; Tsuyoshi Miyakawa; Hajime Yamanaka; Hiroshi Maeno; Keiji Wada; Hiroshi Kunugi

  BEHAVIOURAL BRAIN RESEARCH ELSEVIER SCIENCE BV 180 (1) 69 - 76 0166-4328 2007/06 [Refereed]
  
• Failure to confirm an association between the PLXNA2 gene and schizophrenia in a Japanese population

  Takashi Fujii; Yoshimi Iijima; Hitomi Kondo; Tomoko Shizuno; Hiroaki Hori; Tetsuo Nakabayashi; Kunimasa Arima; Osamu Saitoh; Hiroshi Kunugi

  PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY PERGAMON-ELSEVIER SCIENCE LTD 31 (4) 873 - 877 0278-5846 2007/05 [Refereed]
  
• Association analysis of ATF4 and ATF5, genes for interacting-proteins of DISC1, in bipolar disorder

  Chihiro Kakiuchi; Mizuho Ishiwata; Shinichiro Nanko; Hiroshi Kunugi; Yoshio Minabe; Kazuhiko Nakamura; Norio Mori; Kumiko Fujii; Kazuo Yamada; Takeo Yoshikawa; Tadafumi Kato

  NEUROSCIENCE LETTERS ELSEVIER IRELAND LTD 417 (3) 316 - 321 0304-3940 2007/05 [Refereed]
  
• Sequence and functional analyses of mtDNA in a maternally inherited family with bipolar disorder and depression

  Kae Munakata; Kumiko Fujii; Shinichiro Nanko; Hiroshi Kunugi; Tadafumi Kato

  MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS ELSEVIER SCIENCE BV 617 (1-2) 119 - 124 0027-5107 2007/04 [Refereed]
  
• Gene expression in the peripheral leukocytes and association analysis of PDLIM5 gene in schizophrenia

  Shusuke Numata; Shu-ichi Ueno; Jun-ichi Iga; Ken Yamauchi; Song Hongwei; Ryota Hashimoto; Masatoshi Takeda; Hiroshi Kunugi; Mitsuo Itakura; Tetsuro Ohmori

  NEUROSCIENCE LETTERS ELSEVIER IRELAND LTD 415 (1) 28 - 33 0304-3940 2007/03 [Refereed]
  
• Progressive changes of white matter integrity in schizophrenia revealed by diffusion tensor imaging

  Takeyuki Mori; Takashi Ohnishi; Ryota Hashimoto; Kiyotaka Nemoto; Yoshiya Moriguchi; Hiroko Noguchi; Tetsuo Nakabayashi; Hiroaki Hori; Seichi Harada; Osamu Saitoh; Hiroshi Matsuda; Hiroshi Kunugi

  PSYCHIATRY RESEARCH-NEUROIMAGING ELSEVIER IRELAND LTD 154 (2) 133 - 145 0925-4927 2007/02 [Refereed]
  
• 17 beta-estradiol protects cortical neurons against oxidative stress-induced cell death through reduction in the activity of mitogen-activated protein kinase and in the accumulation of intracellular calcium

  Yumiko Numakawa; Tomoya Matsumoto; Daisaku Yokomaku; Takahisa Taguchi; Etsuo Niki; Hiroshi Hatanaka; Hiroshi Kunugi; Tadahiro Numakawa

  ENDOCRINOLOGY OXFORD UNIV PRESS INC 148 (2) 627 - 637 0013-7227 2007/02 [Refereed]
  
• Progressive changes of white matter integrity in schizophrenia revealed by diffusion tensor imaging.

  Mori T; Ohnishi T; Hashimoto R; Nemoto K; Moriguchi Y; Noguchi H; Nakabayashi T; Hori H; Harada S; Saitoh O; Matsuda H; Kunugi H

  Psychiatry research 2 154 (2) 133 - 145 0165-1781 2007/02 [Refereed]
  
• [Premorbid stress vulnerability and genetic polymorphism of brain-derived neurotrophic factor].

  Kunugi H

  Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica 8 109 (8) 771 - 776 0033-2658 2007 [Refereed]
  
• Effects of switching from conventional antipsychotics to risperidone in Japanese patients with chronic schizophrenia

  Shinsuke Nakanishi; Hiroshi Kunugi; Robin M. Murray; Seiji Nojima; Toyoaki Ogawa; Toshihiko Takahashi

  PSYCHIATRY AND CLINICAL NEUROSCIENCES BLACKWELL PUBLISHING 60 (6) 751 - 757 1323-1316 2006/12 [Refereed]
  
• Association study of the vesicular monoamine transporter 1 (VMAT1) gene with schizophrenia in a Japanese population

  Misty Richards; Yoshimi Iijima; Hitomi Kondo; Tomoko Shizuno; Hiroaki Hori; Kunimasa Arima; Osamu Saitoh; Hiroshi Kunugi

  Behavioral and Brain Functions 2 39  1744-9081 2006/11 [Refereed]
  
• Molecular genetics of schizophrenia

  功刀 浩

  神経研究の進歩 株式会社医学書院 50 (5) 693 - 702 0001-8724 2006/10
• Possible association between nonsynonymous polymorphisms of the anaplastic lymphoma kinase (ALK) gene and schizophrenia in a Japanese population

  H. Kunugi; R. Hashimoto; T. Okada; H. Hori; T. Nakabayashi; A. Baba; K. Kudo; M. Omori; S. Takahashi; R. Tsukue; K. Anami; N. Hirabayashi; A. Kosuga; M. Tatsumi; K. Kamijima; T. Asada; S. Harada; K. Arima; O. Saitoh

  JOURNAL OF NEURAL TRANSMISSION SPRINGER WIEN 113 (10) 1569 - 1573 0300-9564 2006/10 [Refereed]
  
• Impact of the DISC1 Ser704Cys polymorphism on risk for major depression, brain morphology and ERK signaling

  Ryota Hashimoto; Tadahiro Numakawa; Takashi Ohnishi; Emi Kumamaru; Yuki Yagasaki; Tetsuya Ishimoto; Takeyuki Mori; Kiyotaka Nemoto; Naoki Adachi; Aiko Izumi; Sachie Chiba; Hiroko Noguchi; Tatsuyo Suzuki; Nakao Iwata; Norio Ozaki; Takahisa Taguchi; Atsushi Kamiya; Asako Kosuga; Masahiko Tatsumi; Kunitoshi Kamijima; Daniel R. Weinberger; Akira Sawa; Hiroshi Kunugi

  HUMAN MOLECULAR GENETICS OXFORD UNIV PRESS 15 (20) 3024 - 3033 0964-6906 2006/10 [Refereed]
  
• Effect of antipsychotic drugs on DISC1 and dysbindin expression in mouse frontal cortex and hippocampus

  S. Chiba; R. Hashimoto; S. Hattori; M. Yohda; B. Lipska; D. R. Weinberger; H. Kunugi

  JOURNAL OF NEURAL TRANSMISSION SPRINGER WIEN 113 (9) 1337 - 1346 0300-9564 2006/09 [Refereed]
  
• Antipsychotic medication and cognitive function in schizophrenia

  Hiroaki Hori; Hiroko Noguchi; Ryota Hashimoto; Tetsuo Nakabayashi; Mayu Omori; Sho Takahashi; Ryotaro Tsukue; Kimitaka Anami; Naotsugu Hirabayashi; Seiichi Harada; Osamu Saitoh; Masao Iwase; Osami Kajimoto; Masatoshi Takeda; Shigeo Okabe; Hiroshi Kunugi

  SCHIZOPHRENIA RESEARCH ELSEVIER SCIENCE BV 86 (1-3) 138 - 146 0920-9964 2006/09 [Refereed]
  
• 統合失調症型人格障害評価尺度(SPQ)と認知機能の関連

  野口 広子; 堀 弘明; 功刀 浩

  神経化学 (一社)日本神経化学会 45 (2-3) 377 - 377 0037-3796 2006/08
• IMPA2のプロモータハプロタイプは転写を促進することによって双極性障害危険因子に関わっている(A Promoter Haplotype of IMPA2 Possibly Confers Risk for Bipolar Disorder by Enhancing Transcription)

  Ohnishi Tetsuo; Yamada Kazuo; Ohba Hisako; Iwayama Yoshimi; Toyota Tomoko; Inada Toshiya; Kunugi Hiroshi; Tatsumi Masahiko; Ozaki Norio; Iwata Nakao; Sakamoto Kaoru; Iijima Yoshimi; Iwata Yasuhide; Tsuchiya Kenji; Sugihara Gen-ichi; Nanko Shinichiro; Osumi Noriko; Detera-Wadleigh Sevilla; Kato Tadafumi; Yoshikawa Takeo

  神経化学 (一社)日本神経化学会 45 (2-3) 490 - 490 0037-3796 2006/08
• A complex polymorphic region in the brain-derived neurotrophic factor (BDNF) gene confers susceptibility to bipolar disorder and affects transcriptional activity

  T Okada; R Hashimoto; T Numakawa; Y Iijima; A Kosuga; M Tatsumi; K Kamijima; T Kato; H Kunugi

  MOLECULAR PSYCHIATRY NATURE PUBLISHING GROUP 11 (7) 695 - 703 1359-4184 2006/07 [Refereed]
  
• Chronic antidepressants potentiate via sigma-1 receptors the brain-derived neurotrophic factor-induced signaling for glutamate release

  Y Yagasaki; T Numakawa; E Kumamaru; T Hayashi; TP Su; H Kunugi

  JOURNAL OF BIOLOGICAL CHEMISTRY AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC 281 (18) 12941 - 12949 0021-9258 2006/05 [Refereed]
  
• Vitamin E protected cultured cortical neurons from oxidative stress-induced cell death through the activation of mitogen-activated protein kinase and phosphatidylinositol 3-kinase

  Y Numakawa; T Numakawa; T Matsumoto; Y Yagasaki; E Kumamaru; H Kunugi; T Taguchi; E Niki

  JOURNAL OF NEUROCHEMISTRY BLACKWELL PUBLISHING 97 (4) 1191 - 1202 0022-3042 2006/05 [Refereed]
  
• Psychostimulant-induced attenuation of hyperactivity and prepulse inhibition deficits in Adcyap1-deficient mice

  K Tanaka; N Shintani; H Hashimoto; N Kawagishi; Y Ago; T Matsuda; R Hashimoto; H Kunugi; A Yamamoto; C Kawaguchi; T Shimada; A Baba

  JOURNAL OF NEUROSCIENCE SOC NEUROSCIENCE 26 (19) 5091 - 5097 0270-6474 2006/05 [Refereed]
  
• An association study of bipolar disorder with chromogranin B gene

  Iljima Y; Inada T; Kunugi H; Okada T; Sakamoto K; Fukunaga T; Arinami T; Ohtsuki T; Yoshikawa T; Yamada K; Ozaki N; Iwata N; Kato T; Tatsumi M; Nanko S

  BIOLOGICAL PSYCHIATRY 59 (8) 209S-209S  0006-3223 2006/04 [Refereed]
  
• Susceptibility genes for schizophrenia

  R Hashimoto; S Hattori; S Chiba; Y Yagasaki; T Okada; E Kumamaru; T Mori; K Nemoto; H Tanii; H Hori; H Noguchi; T Numakawa; T Ohnishi; H Kunugi

  PSYCHIATRY AND CLINICAL NEUROSCIENCES BLACKWELL PUBLISHING 60 S4 - S10 1323-1316 2006/04 [Refereed]
  
• The Val66Met polymorphism of the brain-derived neurotrophic factor gene affects age-related brain morphology

  K Nemoto; T Ohnishi; T Mori; Y Moriguchi; R Hashimoto; T Asada; H Kunugi

  NEUROSCIENCE LETTERS ELSEVIER IRELAND LTD 397 (1-2) 25 - 29 0304-3940 2006/04 [Refereed]
  
• Lithium response and Val66Met polymorphism of the brain-derived neurotrophic factor gene in Japanese patients with bipolar disorder

  T Masui; R Hashimoto; Kusumi, I; K Suzuki; T Tanaka; S Nakagawa; T Suzuki; N Iwata; N Ozaki; T Kato; H Kunugi; T Koyama

  PSYCHIATRIC GENETICS LIPPINCOTT WILLIAMS & WILKINS 16 (2) 49 - 50 0955-8829 2006/04 [Refereed]
  
• A possible association between the-116C/G single nucleotide polymorphism of the XBP1 gene and lithium prophylaxis in bipolar disorder

  T Masui; R Hashimoto; Kusumi, I; K Suzuki; T Tanaka; S Nakagawa; H Kunugi; T Koyama

  INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY CAMBRIDGE UNIV PRESS 9 (1) 83 - 88 1461-1457 2006/02 [Refereed]
  
• The association between the Val158Met polymorphism of the catechol-O-methyl transferase gene and morphological abnormalities of the brain in chronic schizophrenia

  T Ohnishi; R Hashimoto; T Mori; K Nemoto; Y Moriguchi; H Iida; H Noguchi; T Nakabayashi; H Hori; M Ohmori; R Tsukue; K Anami; N Hirabayashi; S Harada; K Arima; O Saitoh; H Kunugi

  BRAIN OXFORD UNIV PRESS 129 (Pt 2) 399 - 410 0006-8950 2006/02 [Refereed]
  
• An association study of schizophrenia with complex polymorphic region in the BDNF gene.

  Iijima, Y; Okada, T; Hashimoto, R; Shizuno, T; Hori, H; Nakabayashi, T; Kato, T; Asada, T; Tatsumi, M; Kosuga, A; Kamijima, K; Harada, S; Arima, K; Saitoh, O; Kunugi, H

  Am J Med Genet Neuropsychiatr Genet. 141B (7) 26  2006/01 [Refereed]
  
• Assessment of the dexamethasone/CRH test as a state-dependent marker for hypothalamic-pituitary-adrenal (HPA) axis abnormalities in major depressive episode: A multicenter study

  H Kunugi; Ida, I; T Owashi; M Kimura; Y Inoue; S Nakagawa; T Yabana; T Urushibara; R Kanai; M Aihara; N Yuuki; T Otsubo; A Oshima; K Kudo; T Inoue; Y Kitaichi; O Shirakawa; K Isogawa; H Nagayama; K Kamijima; S Nanko; S Kanba; T Higuchi; M Mikuni

  NEUROPSYCHOPHARMACOLOGY NATURE PUBLISHING GROUP 31 (1) 212 - 220 0893-133X 2006/01 [Refereed]
  
• Brain-derived neurotrophic factor-induced potentiation of glutamate and GABA release: Different dependency on signaling pathways and neuronal activity

  T Matsumoto; T Numakawa; D Yokomaku; N Adachi; S Yamagishi; Y Numakawa; H Kunugi; T Taguchi

  MOLECULAR AND CELLULAR NEUROSCIENCE ACADEMIC PRESS INC ELSEVIER SCIENCE 31 (1) 70 - 84 1044-7431 2006/01 [Refereed]
  
• Relationship between XBP1 genotype and personality traits assessed by TO and NEO-FFI

  L Kusumi; T Masui; C Kakiuchi; K Suzuki; T Akimoto; R Hashimoto; H Kunugi; T Kato; T Koyama

  NEUROSCIENCE LETTERS ELSEVIER IRELAND LTD 391 (1-2) 7 - 10 0304-3940 2005/12 [Refereed]
  
• Genomewide high-density SNP linkage analysis of 236 Japanese families supports the existence of schizophrenia susceptibility loci on chromosomes 1p, 14q, and 20p

  T Arinami; T Arinami; T Ohtsuki; H Ishiguro; H Ujike; Y Tanaka; Y Morita; M Mineta; M Takeichi; S Yamada; A Imamura; K Ohara; H Shibuya; K Ohara; Y Suzuki; T Muratake; N Kaneko; T Someya; T Inada; T Yoshikawa; T Toyota; K Yamada; T Kojima; S Takahashi; O Osamu; T Shinkai; M Nakamura; H Fukuzako; T Hashiguchi; S Niwa; T Ueno; H Tachikawa; T Hori; T Asada; S Nanko; H Kunugi; R Hashimoto; N Ozaki; N Iwata; M Harano; H Arai; T Ohnuma; Kusumi, I; T Koyama; H Yoneda; Y Fukumaki; H Shibata; S Kaneko; H Higuchi; N Yasui-Furukori; Y Numachi; M Itokawa; Y Okazaki

  AMERICAN JOURNAL OF HUMAN GENETICS CELL PRESS 77 (6) 937 - 944 0002-9297 2005/12 [Refereed]
  
• Functional polymorphisms of HSPA5: Possible association with bipolar disorder

  C Kakiuchi; M Ishiwata; S Nanko; H Kunugi; Y Minabe; K Nakamura; N Mori; K Fujii; T Umekage; M Tochigi; K Kohda; T Sasaki; K Yamada; T Yoshikawa; T Kato

  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS ACADEMIC PRESS INC ELSEVIER SCIENCE 336 (4) 1136 - 1143 0006-291X 2005/11 [Refereed]
  
• The Gem interacting protein (GMIP) gene is associated with major depressive disorder

  K Tadokoro; R Hashimoto; M Tatsumi; A Kosuga; K Kamijima; H Kunugi

  NEUROGENETICS SPRINGER 6 (3) 127 - 133 1364-6745 2005/09 [Refereed]
  
• Mitochondrial DNA sequence analysis of patients with 'atypical psychosis'

  AA Kazuno; K Munakata; K Mori; M Tanaka; S Nanko; H Kunugi; T Umekage; M Tochigi; K Kohda; T Sasaki; T Akiyama; S Washizuka; N Kato; T Kato

  PSYCHIATRY AND CLINICAL NEUROSCIENCES BLACKWELL PUBLISHING 59 (4) 497 - 503 1323-1316 2005/08 [Refereed]
  
• The breakpoint cluster region gene on chromosome 22q11 is associated with bipolar disorder

  R Hashimoto; T Okada; T Kato; A Kosuga; M Tatsumi; K Kamijima; H Kunugi

  BIOLOGICAL PSYCHIATRY ELSEVIER SCIENCE INC 57 (10) 1097 - 1102 0006-3223 2005/05 [Refereed]
  
• Evidence of novel neuronal functions of dysbindin, a susceptibility gene for schizophrenia

  Hashimoto R; Numakawa T; Yagasaki Y; Ishimoto T; Okada T; Suzuki T; Iwata N; Ozaki N; Taguchi T; Tatsumi M; Kamijima K; Straub R; Weinberger D; Kunugi H

  SCHIZOPHRENIA BULLETIN 31 (2) 268-269  0586-7614 2005/04 [Refereed]
  
• A missense polymorphism (H204R) of a Rho GTPase-activating protein, the chimerin 2 gene, is associated with schizophrenia in men

  R Hashimoto; M Yoshida; H Kunugi; N Ozaki; Y Yamanouchi; N Iwata; T Suzuki; T Kitajima; M Tatsumi; K Kamijima

  SCHIZOPHRENIA RESEARCH ELSEVIER SCIENCE BV 73 (2-3) 383 - 385 0920-9964 2005/03 [Refereed]
  
• Association study of the frizzled-3 (FZD3) gene with schizophrenia and mood disorders

  R Hashimoto; T Suzuki; N Iwata; Y Yamanouchi; T Kitajima; A Kosuga; M Tatsumi; N Ozaki; K Kamijima; H Kunugi

  JOURNAL OF NEURAL TRANSMISSION SPRINGER WIEN 112 (2) 303 - 307 0300-9564 2005/02 [Refereed]
  
• Mitochondrial DNA 3644T -> C mutation associated with bipolar disorder

  K Munakata; M Tanaka; K Mori; S Washizuka; M Yoneda; O Tajima; T Akiyama; S Nanko; H Kunugi; K Tadokoro; N Ozaki; T Inada; K Sakamoto; T Fukunaga; Y Iijima; N Iwata; M Tatsumi; K Yamada; T Yoshikawa; T Kato

  GENOMICS ACADEMIC PRESS INC ELSEVIER SCIENCE 84 (6) 1041 - 1050 0888-7543 2004/12 [Refereed]
  
• Evidence of novel neuronal functions of dysbindin, a susceptibility gene for schizophrenia

  T Numakawa; Y Yagasaki; T Ishimoto; T Okada; T Suzuki; N Iwata; N Ozaki; T Taguchi; M Tatsumi; K Kamijima; RE Straub; DR Weinberger; H Kunugi; R Hashimoto

  HUMAN MOLECULAR GENETICS OXFORD UNIV PRESS 13 (21) 2699 - 2708 0964-6906 2004/11 [Refereed]
  
• Neuronal roles of the integrin-associated protein (IAP/CD47) in developing cortical neurons

  T Numakawa; T Ishimoto; S Suzuki; Y Numakawa; N Adachi; T Matsumoto; D Yokomaku; H Koshimizu; KE Fujimori; R Hashimoto; T Taguchi; H Kunugi

  JOURNAL OF BIOLOGICAL CHEMISTRY AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC 279 (41) 43245 - 43253 0021-9258 2004/10 [Refereed]
  
• Lack of association between XBP1 genotype and calcium signaling in the platelets of healthy subjects

  Kusumi, I; T Masui; C Kakiuchi; K Suzuki; T Akimoto; R Hashimoto; H Kunugi; T Kato; T Koyama

  NEUROSCIENCE LETTERS ELSEVIER SCI IRELAND LTD 369 (1) 1 - 3 0304-3940 2004/10 [Refereed]
  
• Association of mitochondrial complex I subunit gene NDUFV2 at 18p11 with bipolar disorder in Japanese and the national institute of mental health pedigrees

  S Washizuka; K Iwamoto; AA Kazuno; C Kakiuchi; K Mori; M Kametani; K Yamada; H Kunugi; O Tajima; T Akiyama; S Nanko; T Yoshikawa; T Kato

  BIOLOGICAL PSYCHIATRY ELSEVIER SCIENCE INC 56 (7) 483 - 489 0006-3223 2004/10 [Refereed]
  
• No association between the Val66Met polymorphism of the brain-derived neurotrophic factor gene and bipolar disorder in a Japanese population: a Multicenter study

  H Kunugi; Y Iijima; M Tatsumi; M Yoshida; R Hashimoto; T Kato; K Sakamoto; T Fukunaga; T Inada; T Suzuki; N Iwata; N Ozaki; K Yamada; T Yoshikawa

  BIOLOGICAL PSYCHIATRY ELSEVIER SCIENCE INC 56 (5) 376 - 378 0006-3223 2004/09 [Refereed]
  
• A Missense polymorphism (S205L) of the low-affinity neurotrophin receptor p75NTR gene is associated with depressive disorder and attempted suicide

  Hiroshi Kunugi; Ryota Hashimoto; Mariko Yoshida; Masahiko Tatsumi; Kunitoshi Kamijima

  American Journal of Medical Genetics - Neuropsychiatric Genetics 1 129 (1) 44 - 46 1552-4841 2004/08 [Refereed]
  
• A missense polymorphism (S205L) of the low-affinity neurotrophin receptor p75(NTR) gene is associated with depressive disorder and attempted suicide

  H Kunugi; R Hashimoto; M Yoshida; M Tatsumi; K Kamijima

  AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS WILEY-LISS 129B (1) 44 - 46 0148-7299 2004/08 [Refereed]
  
• RNAi induction and activation in mammalian muscle cells where Dicer and eIF2C translation initiation factors are barely expressed

  N Sago; K Omi; Y Tamura; H Kunugi; T Toyo-oka; K Tokunaga; H Hohjoh

  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS ACADEMIC PRESS INC ELSEVIER SCIENCE 319 (1) 50 - 57 0006-291X 2004/06 [Refereed]
  
• Efficacy of milnacipran for depressive symptoms in schizophrenia spectrum disorders

  S Nakanishi; H Kunugi; T Takahashi

  PSYCHIATRY AND CLINICAL NEUROSCIENCES BLACKWELL PUBLISHING ASIA 58 (2) 226 - 227 1323-1316 2004/04 [Refereed]
  
• Combined DEX/CRH test among Japanese patients with major depression

  H Kunugi; T Urushibara; S Nanko

  JOURNAL OF PSYCHIATRIC RESEARCH PERGAMON-ELSEVIER SCIENCE LTD 38 (2) 123 - 128 0022-3956 2004/03 [Refereed]
  
• Association analysis of the -308G > A promoter polymorphism of the tumor necrosis factor alpha (TNF-alpha) gene in Japanese patients with schizophrenia

  R Hashimoto; M Yoshida; N Ozaki; Y Yamanouchi; N Iwata; T Suzuki; T Kitajima; M Tatsumi; K Kamijima; H Kunugi

  JOURNAL OF NEURAL TRANSMISSION SPRINGER-VERLAG WIEN 111 (2) 217 - 221 0300-9564 2004/02 [Refereed]
  
• Analysis of the Fyn Kinase Gene in Alzheimer's Disease and Schizophrenia

  Yuko Nakano; Akihisa Akahane; Hiroshi Tanaka; Mikako Ueno; Hiroshi Kunugi; Shinichiro Nanko

  Brain and Nerve 2 56 (2) 153 - 156 0006-8969 2004/02 [Refereed]
  
• Analysis of enhancer activity of a dinucleotide repeat polymorphism in the neurotrophin-3 gene and its association with bipolar disorder

  K Tadokoro; R Hashimoto; M Tatsumi; K Kamijima; H Kunugi

  NEUROPSYCHOBIOLOGY KARGER 50 (3) 206 - 210 0302-282X 2004 [Refereed]
  
• Lack of support for a genetic association of the XBP1 promoter polymorphism with bipolar disorder in probands of European origin - Reply

  Kakiuchi C; Nanko S; Kunugi H; Kato T

  Nature Genetics 36 (8) 784 - 785 2004 [Refereed]
  
• Impaired feedback regulation of XBP1 as a genetic risk factor for bipolar disorder

  C Kakiuchi; K Iwamoto; M Ishiwata; M Bundo; T Kasahara; Kusumi, I; T Tsujita; Y Okazaki; S Nanko; H Kunugi; T Sasaki; T Kato

  NATURE GENETICS NATURE PUBLISHING GROUP 35 (2) 171 - 175 1061-4036 2003/10 [Refereed]
  
• Brain-derived neurotrophic factor gene and schizophrenia: polymorphism screening and association analysis

  S Nanko; H Kunugi; H Hirasawa; N Kato; T Nabika; S Kobayashi

  SCHIZOPHRENIA RESEARCH ELSEVIER SCIENCE BV 62 (3) 281 - 283 0920-9964 2003/08 [Refereed]
  
• Association of mitochondrial complex I subunit gene NDUFV2 at 18p11 with bipolar disorder

  S Washizuka; C Kakiuchi; K Mori; H Kunugi; O Tajima; T Akiyama; S Nanko; T Kato

  AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS WILEY-BLACKWELL 120B (1) 72 - 78 1552-4841 2003/07 [Refereed]
  
• Prenatal underdevelopment and schizophrenia: A case report of monozygotic twins

  H Kunugi; T Urushibara; RM Murray; S Nanko; T Hirose

  PSYCHIATRY AND CLINICAL NEUROSCIENCES BLACKWELL PUBLISHING ASIA 57 (3) 271 - 274 1323-1316 2003/06 [Refereed]
  
• No association of mutations and mRNA expression of WFS1/wolframin with bipolar disorder in humans

  T Kato; K Iwamoto; S Washizuka; K Mori; O Tajima; T Akiyama; S Nanko; H Kunugi; N Kato

  NEUROSCIENCE LETTERS ELSEVIER SCI IRELAND LTD 338 (1) 21 - 24 0304-3940 2003/02 [Refereed]
  
• Association analysis of polymorphic CGG repeat in 5 ' UTR of the reelin and VLDLR genes with schizophrenia

  A Akahane; H Kunugi; H Tanaka; S Nanko

  SCHIZOPHRENIA RESEARCH ELSEVIER SCIENCE BV 58 (1) 37 - 41 0920-9964 2002/11 [Refereed]
  
• Possible effect of the APOE epsilon 4 allele on the hippocampal volume and asymmetry in schizophrenia

  S Nanko

  AMERICAN JOURNAL OF MEDICAL GENETICS WILEY-LISS 114 (6) 641 - 642 0148-7299 2002/08 [Refereed]
  
• Novel polymorphisms in the promoter region of the neurotrophin-3 gene and their associations with schizophrenia

  Mineko Hattori; Hiroshi Kunugi; Akihisa Akahane; Hiroshi Tanaka; Sugiko Ishida; Tetsuya Hirose; Ryoji Morita; Kazuhiro Yamakawa; Shinichiro Nanko

  American Journal of Medical Genetics - Neuropsychiatric Genetics 114 (3) 304 - 309 1552-4841 2002/04 [Refereed]
  
• Novel polymorphisms in the promoter region of the neurotrophin-3 gene and their associations with schizophrenia

  M Hattori; H Kunugi; A Akahane; H Tanaka; S Ishida; T Hirose; R Morita; K Yamakawa; S Nanko

  AMERICAN JOURNAL OF MEDICAL GENETICS WILEY-LISS 114 (3) 304 - 309 0148-7299 2002/04 [Refereed]
  
• Association study of C825T polymorphism of the G-protein b3 subunit gene with schizophrenia and mood disorders

  H Kunugi; T Kato; R Fukuda; M Tatsumi; T Sakai; S Nanko

  JOURNAL OF NEURAL TRANSMISSION SPRINGER-VERLAG WIEN 109 (2) 213 - 218 0300-9564 2002 [Refereed]
  
• Glial cell line-derived neurotrophic factor (GDNF) gene and schizophrenia: polymorphism screening and association analysis

  KB Lee; H Kunugi; S Nanko

  PSYCHIATRY RESEARCH ELSEVIER SCI IRELAND LTD 104 (1) 11 - 17 0165-1781 2001/10 [Refereed]
  
• [Low serum cholesterol and suicidal behavior].

  Kunugi H

  Nihon rinsho. Japanese journal of clinical medicine 8 59 1599 - 1604 0047-1852 2001/08 [Refereed]
  
• Exon/intron boundaries, novel polymorphisms, and association analysis with schizophrenia of the human synaptic vesicle monoamine transporter (SVMT) gene

  H Kunugi; S Ishida; A Akahane; S Nanko

  MOLECULAR PSYCHIATRY NATURE PUBLISHING GROUP 6 (4) 456 - 460 1359-4184 2001/07 [Refereed]
  
• Obstetric complications and schizophrenia: prenatal underdevelopment and subsequent neurodevelopmental impairment.

  Kunugi H; Nanko S; Murray RM

  The British journal of psychiatry. Supplement 40 s25 - 9 0960-5371 2001/04 [Refereed]
  
• Obstetric complications and schizophrenia: prenatal underdevelopment and subsequent neurodevelopmental impairment

  H Kunugi; S Nanko; RM Murray

  BRITISH JOURNAL OF PSYCHIATRY ROYAL COLLEGE OF PSYCHIATRISTS 178 S25 - S29 0007-1250 2001/04 [Refereed]
  
• Mitochondrial DNA polymorphisms in bipolar disorder

  T Kato; H Kunugi; S Nanko; N Kato

  JOURNAL OF AFFECTIVE DISORDERS ELSEVIER SCIENCE BV 62 (3) 151 - 164 0165-0327 2001/02 [Refereed]
  
• A novel polymorphism of the brain-derived neurotrophic factor (BDNF) gene associated with late-onset Alzheimer's disease

  H Kunugi; A Ueki; M Otsuka; K Isse; H Hirasawa; N Kato; T Nabika; S Kobayashi; S Nanko

  MOLECULAR PSYCHIATRY NATURE PUBLISHING GROUP 6 (1) 83 - 86 1359-4184 2001/01 [Refereed]
  
• trkC遺伝子の精神神経疾患における多型解析.

  赤羽晃寿; 功刀 浩; 植木 彰; 大塚美恵子; 一瀬邦弘; 平沢秀人; 南光進一郎

  精神薬療研究年報 33 38 - 42 2001
• Alzheimer's disease and 5-HTTLPR polymorphism of the serotonin transporter gene: No evidence for an association

  Hiroshi Kunugi; Akira Ueki; Mieko Otsuka; Kunihiro Isse; Hideto Hirasawa; Norihiro Kato; Toru Nabika; Shotai Kobayashi; Shinichiro Nanko

  American Journal of Medical Genetics - Neuropsychiatric Genetics 96 (3) 307 - 309 1552-4841 2000/06 [Refereed]
  
• Alzheimer's disease and 5-HTTLPR polymorphism of the serotonin transporter gene: No evidence for an association

  H Kunugi; A Ueki; M Otsuka; K Isse; H Hirasawa; N Kato; T Nabika; S Kobayashi; S Nanko

  AMERICAN JOURNAL OF MEDICAL GENETICS WILEY-LISS 96 (3) 307 - 309 0148-7299 2000/06 [Refereed]
  
• Intra-uterine physical growth in schizophrenia: evidence confirming excess of premature birth

  M Ichiki; H Kunugi; N Takei; RM Murray; H Baba; H Arai; Oshima, I; K Okagami; T Sato; T Hirose; S Nanko

  PSYCHOLOGICAL MEDICINE CAMBRIDGE UNIV PRESS 30 (3) 597 - 604 0033-2917 2000/05 [Refereed]
  
• Association of bipolar disorder with the 5178 polymorphism in mitochondrial DNA

  Tadafumi Kato; Hiroshi Kunugi; Shinichiro Nanko; Nobumasa Kato

  American Journal of Medical Genetics - Neuropsychiatric Genetics 96 (2) 182 - 186 1552-4841 2000/04 [Refereed]
  
• Association of bipolar disorder with the 5178 polymorphism in mitochondrial DNA

  T Kato; H Kunugi; S Nanko; N Kato

  AMERICAN JOURNAL OF MEDICAL GENETICS WILEY-LISS 96 (2) 182 - 186 0148-7299 2000/04 [Refereed]
  
• No evidence for an association between the Glu298Asp polymorphism of the NOS3 gene and Alzheimer's disease

  H Kunugi; A Akahane; A Ueki; M Otsuka; K Isse; H Hirasawa; N Kato; T Nabika; S Kobayashi; S Nanko

  JOURNAL OF NEURAL TRANSMISSION SPRINGER-VERLAG WIEN 107 (8-9) 1081 - 1084 0300-9564 2000 [Refereed]
  
• 精神分子遺伝学—特集 ゲノム医学の現在と未来--基礎と臨床 ; 多因子病

  功刀 浩

  現代医療 現代医療社 32 (1) 253 - 258 0533-7259 2000/01
• Candidate Gene Approaches to Schizophrenia: Focus on the Dopamine Hypothesis

  Hiroshi Kunugi

  International Journal of Mental Health M.E. Sharpe Inc. 29 (3) 39 - 65 0020-7411 2000 [Refereed]
  
• 機能性精神病の候補遺伝子アプローチ.

  功刀 浩; 石田杉子; 加藤忠史; 巽 雅彦; 坂井俊之; 赤羽晃寿; 服部峰子; 南光進一郎

  厚生省精神・神経疾患研究委託費、「精神疾患の分子生物学的研究」（主任研究者 西川徹）平成９～11年度研究報告書 37 - 40 2000
• Cytogenetic findings in 250 schizophrenics: evidence confirming an excess of the X chromosome aneuploidies and pericentric inversion of chromosome 9

  H Kunugi; KB Lee; S Nanko

  SCHIZOPHRENIA RESEARCH ELSEVIER SCIENCE BV 40 (1) 43 - 47 0920-9964 1999/11 [Refereed]
  
• Novel polymorphism in the promoter region of the tumor necrosis factor alpha gene: No association with narcolepsy

  Tadafumi Kato; Makoto Honda; Shouji Kuwata; Takeo Juji; Hiroshi Kunugi; Shinichiro Nanko; Masato Fukuda; Yutaka Honda

  American Journal of Medical Genetics - Neuropsychiatric Genetics 88 (4) 301 - 304 1552-4841 1999/08 [Refereed]
  
• Novel polymorphism in the promoter region of the tumor necrosis factor alpha gene: No association with narcolepsy

  T Kato; M Honda; S Kuwata; T Juji; H Kunugi; S Nanko; M Fukuda; Y Honda

  AMERICAN JOURNAL OF MEDICAL GENETICS WILEY-LISS 88 (4) 301 - 304 0148-7299 1999/08 [Refereed]
  
• Familial paroxysmal kinesigenic choreoathetosis: An electrophysiologic and genotypic analysis

  M Sadamatsu; A Masui; T Sakai; H Kunugi; S Nanko; N Kato

  EPILEPSIA LIPPINCOTT WILLIAMS & WILKINS 40 (7) 942 - 949 0013-9580 1999/07 [Refereed]
  
• A functional polymorphism in the promoter region of monoamine oxidase-A gene and mood disorders

  H Kunugi; S Ishida; T Kato; M Tatsumi; T Sakai; M Hattori; T Hirose; S Nanko

  MOLECULAR PSYCHIATRY STOCKTON PRESS 4 (4) 393 - 395 1359-4184 1999/07 [Refereed]
  
• Dinucleotide repeat polymorphism in the neurotrophin-3 gene and hippocampal volume in psychoses

  H Kunugi; M Hattori; S Nanko; K Fujii; T Kato; S Nanko

  SCHIZOPHRENIA RESEARCH ELSEVIER SCIENCE BV 37 (3) 271 - 273 0920-9964 1999/06 [Refereed]
  
• Sixth World Congress of Psychiatric Genetics X Chromosome Workshop

  AD Paterson; L DeLisi; SV Faraone; PV Gejman; D Goossens; Hovatta, I; CA Kaufmann; SM Klauck; H Kunugi; DF Levinson; O Mors; N Norton; SL Smalley

  AMERICAN JOURNAL OF MEDICAL GENETICS WILEY-LISS 88 (3) 279 - 286 0148-7299 1999/06 [Refereed]
  
• No evidence for an association of polymorphisms of the tryptophan hydroxylase gene with affective disorders or attempted suicide among Japanese patients

  H Kunugi; S Ishida; T Kato; T Sakai; M Tatsumi; T Hirose; S Nanko

  AMERICAN JOURNAL OF PSYCHIATRY AMER PSYCHIATRIC PRESS, INC 156 (5) 774 - 776 0002-953X 1999/05 [Refereed]
  
• Association between serotonin transporter gene polymorphism and anxiety- related traits

  Satomi Katsuragi; Hiroshi Kunugi; Akira Sano; Takashi Tsutsumi; Koichi Isogawa; Shinichiro Nanko; Jotaro Akiyoshi

  Biological Psychiatry 3 45 (3) 368 - 370 0006-3223 1999/02 [Refereed]
  
• No changes in paired viral antibody titers during the course of acute schizophrenia

  R Fukuda; T Sasaki; H Kunugi; S Nanko

  NEUROPSYCHOBIOLOGY KARGER 40 (2) 57 - 62 0302-282X 1999 [Refereed]
  
• 分子遺伝学からみたストレス脆弱性

  功刀浩

  臨床精神医学 28 263 - 270 1999
• The monoamine oxidase-A gene and major psychosis in Japanese subjects

  T Sasaki; M Hattori; T Sakai; T Kato; H Kunugi; T Hirose; S Nanko

  BIOLOGICAL PSYCHIATRY ELSEVIER SCIENCE INC 44 (9) 922 - 924 0006-3223 1998/11 [Refereed]
  
• C677T polymorphism in methylenetetrahydrofolate reductase gene and psychoses

  H Kunugi; R Fukuda; M Hattori; T Kato; M Tatsumi; T Sakai; T Hirose; S Nanko

  MOLECULAR PSYCHIATRY STOCKTON PRESS 3 (5) 435 - 437 1359-4184 1998/09 [Refereed]
  
• Season of birth of chronic alcoholics

  H Kunugi; S Nanko; H Watanabe; K Sekiba; H Kazamatsuri

  JOURNAL OF PSYCHIATRIC RESEARCH PERGAMON-ELSEVIER SCIENCE LTD 32 (5) 321 - 323 0022-3956 1998/09 [Refereed]
  
• Low activity allele of catechol-O-methyltransferase gene associated with rapid cycling bipolar disorder

  G Kirov; KC Murphy; MJ Arranz; Jones, I; F McCandles; H Kunugi; RM Murray; P McGuffin; DA Collier; MJ Owen; N Craddock

  MOLECULAR PSYCHIATRY STOCKTON PRESS 3 (4) 342 - 345 1359-4184 1998/07 [Refereed]
  
• Familial schizophrenia with pericentric inversion of chromosome 9: a case report

  KB Lee; H Kunugi; S Nanko

  SCHIZOPHRENIA RESEARCH ELSEVIER SCIENCE BV 32 (2) 123 - 126 0920-9964 1998/07 [Refereed]
  
• A transmission disequilibrium and linkage analysis of D22S278 marker alleles in 574 families: further support for a susceptibility locus for schizophrenia at 22q12

  H Vallada; D Curtis; P Sham; H Kunugi; JH Zhao; R Murray; P McGuffin; S Nanko; M Owen; M Gill; DA Collier; S Antonarakis; D Housman; H Kazazian; G Nestadt; AE Pulver; RE Straub; CJ MacLean; D Walsh; KS Kendler; L DeLisi; M Polymeropoulos; H Coon; W Byerley; R Lofthouse; E Gershon; L Goldin; R Freedman; C Laurent; S Bodeau-Pean; T d'Amato; M Jay; D Campion; J Mallet; DB Wildenauer; B Lerer; M Albus; M Ackenheil; RP Ebstein; J Hallmayer; W Maier; H Gurling; D Curtis; G Kalsi; J Brynjolfsson; T Sigmundson; H Petursson; D Blackwood; W Muri; D StClair; L He; S Maguire; HW Moises; HG Hwu; L Yang; C Wiese; H Kristbjarnarson; DF Levinson; BJ Mowry; H Donis-Keller; NK Hayward; RR Crowe; JM Silverman; DJ Nancarrow; CM Read

  SCHIZOPHRENIA RESEARCH ELSEVIER SCIENCE BV 32 (2) 115 - 121 0920-9964 1998/07 [Refereed]
  
• DLST gene and Alzheimer's disease

  H Kunugi; S Nanko; A Ueki; K Isse; H Hirasawa

  LANCET LANCET LTD 351 (9115) 1584 - 1585 0140-6736 1998/05 [Refereed]
  
• Association study of structural mutations of the tyrosine hydroxylase gene with schizophrenia and Parkinson's disease

  Hiroshi Kunugi; Yasuhara Kawada; Mineko Hattori; Akira Ueki; Mieko Otsuka; Shinichiro Nanko

  American Journal of Medical Genetics - Neuropsychiatric Genetics 81 (2) 131 - 133 1552-4841 1998/03 [Refereed]
  
• Association study of structural mutations of the tyrosine hydroxylase gene with schizophrenia and Parkinson's disease

  H Kunugi; Y Kawada; M Hattori; A Ueki; M Otsuka; S Nanko

  AMERICAN JOURNAL OF MEDICAL GENETICS WILEY-LISS 81 (2) 131 - 133 0148-7299 1998/03 [Refereed]
  
• Possible association of missense mutation (Gly(-63)Glu) of the neurotrophin-3 gene with Alzheimer's disease in Japanese

  H Kunugi; M Hattori; A Ueki; K Isse; H Hirasawa; S Nanko

  NEUROSCIENCE LETTERS ELSEVIER SCI IRELAND LTD 241 (1) 65 - 67 0304-3940 1998/01 [Refereed]
  
• Serotonin transporter gene polymorphisms: ethnic difference and possible association with bipolar affective disorder

  H Kunugi; M Hattori; T Kato; M Tatsumi; T Sakai; T Sasaki; T Hirose; S Nanko

  MOLECULAR PSYCHIATRY STOCKTON PRESS 2 (6) 457 - 462 1359-4184 1997/10 [Refereed]
  
• Season of birth of schizophrenics in a recent Japanese sample

  H Kunugi; S Nanko; N Hayashi; K Saito; T Hirose; H Kazamatsuri

  PSYCHIATRY AND CLINICAL NEUROSCIENCES BLACKWELL SCIENCE 51 (4) 213 - 216 1323-1316 1997/08 [Refereed]
  
• No evidence for an association of affective disorders with high- or low-activity allele of catechol-o-methyltransferase gene

  H Kunugi; HP Vallada; F Hoda; G Kirov; R Gill; KJ Aitchison; D Ball; MJ Arranz; RM Murray; DA Collier

  BIOLOGICAL PSYCHIATRY ELSEVIER SCIENCE INC 42 (4) 282 - 285 0006-3223 1997/08 [Refereed]
  
• Brain-derived neurotrophic factor gene and schizophrenia in Japanese subjects

  T Sasaki; XY Dai; S Kuwata; R Fukuda; H Kunugi; M Hattori; S Nanko

  AMERICAN JOURNAL OF MEDICAL GENETICS WILEY-LISS 74 (4) 443 - 444 0148-7299 1997/07 [Refereed]
  
• Schizophrenia and the ciliary neurotrophic factor (CNTF) gene: No evidence for association

  T Sakai; T Sasaki; M Tatsumi; H Kunugi; M Hattori; S Nanko

  PSYCHIATRY RESEARCH ELSEVIER SCI IRELAND LTD 71 (1) 7 - 10 0165-1781 1997/06 [Refereed]
  
• No association between bipolar disorder and alleles at a functional polymorphism in the COMT gene - Biomed European Bipolar Collaborative Group

  N Craddock; G Spurlock; P McGuffin; MJ Owen; M NostenBertrand; F Bellivier; R Meloni; M Leboyer; J Mallet; L MynettJohnson; Murphy, V; P McKeon; G Kirov; J Powell; H Kunugi; D Collier; M Larosa; B Nacmias; S Sorbi; S Schwab; M Ackenheil; W Maier

  BRITISH JOURNAL OF PSYCHIATRY ROYAL COLLEGE OF PSYCHIATRISTS 170 526 - 528 0007-1250 1997/06 [Refereed]
  
• Genes for interleukin-2 receptor beta chain, interleukin-1 beta, and schizophrenia: No evidence for the association or linkage

  M Tatsumi; T Sasaki; T Sakai; K Kamijima; R Fukuda; H Kunugi; M Hattori; S Nanko

  AMERICAN JOURNAL OF MEDICAL GENETICS WILEY-LISS 74 (3) 338 - 341 0148-7299 1997/05 [Refereed]
  
• Low serum cholesterol in suicide attempters

  H Kunugi; N Takei; H Aoki; S Nanko

  BIOLOGICAL PSYCHIATRY ELSEVIER SCIENCE INC 41 (2) 196 - 200 0006-3223 1997/01 [Refereed]
  
• High and low activity alleles of catechol-O-methyltransferase gene: Ethnic difference and possible association with Parkinson's disease

  H Kunugi; S Nanko; A Ueki; E Otsuka; M Hattori; F Hoda; HP Vallada; MJ Arranz; DA Collier

  NEUROSCIENCE LETTERS ELSEVIER SCI IRELAND LTD 221 (2-3) 202 - 204 0304-3940 1997/01 [Refereed]
  
• Catechol-O-methyltransferase polymorphisms and schizophrenia: A transmission disequilibrium study in multiply affected families

  H. Kunugi; H. P. Vallada; P. C. Sham; F. Hoda; M. J. Arranz; T. Li; S. Nanko; R. M. Murray; P. McGuffin; M. Owen; M. Gill; D. A. Collier

  Psychiatric Genetics 3 7 (3) 97 - 101 0955-8829 1997 [Refereed]
  
• Genes for interleukin-2 receptor β chain, interleukin-1 β, and schizophrenia: No evidence for the association or linkage

  Masahiko Tatsumi; Tsukasa Sasaki; Toshiyuki Sakai; Kunitoshi Kamijima; Rimmei Fukuda; Hiroshi Kunugi; Mineko Hattori; Shinichiro Nanko

  American Journal of Medical Genetics - Neuropsychiatric Genetics 74 (3) 338 - 341 1552-4841 1997 [Refereed]
  
• 特集 精神医学における分子生物学的研究 精神分裂病の分子遺伝学的研究

  功刀 浩; 南光 進一郎

  精神医学 株式会社医学書院 38 (11) 1141 - 1145 0488-1281 1996/11
• Relationship between impairment of prenatal brain growth and family history of psychosis in schizophrenia

  H Kunugi; N Takei; K Saito; S Akizuki; RM Murray; S Nanko

  JOURNAL OF PSYCHIATRIC RESEARCH PERGAMON-ELSEVIER SCIENCE LTD 30 (6) 475 - 481 0022-3956 1996/11 [Refereed]
  
• No association between Parkinson's disease and low-activity alleles of catechol O-methyltransferase

  F Hoda; D Nicholl; P Bennett; M Arranz; KJ Aitchison; A AlChalabi; H Kunugi; H Vallada; PN Leigh; KR Chaudhuri; DA Collier

  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS 228 (3) 780 - 784 0006-291X 1996/11 [Refereed]
  
• A linkage study of schizophrenia with DNA markers from chromosome 8p21-p22 in 25 multiplex families

  D Curtis; HP Vallada; S Nanko; H Kunugi; JF Powell; RM Murray; P McGuffin; MJ Owen; M Gill; DA Collier

  SCHIZOPHRENIA RESEARCH ELSEVIER SCIENCE BV 22 (1) 61 - 68 0920-9964 1996/10 [Refereed]
  
• Perinatal complications and schizophrenia - Data from the Maternal and Child Health Handbook in Japan

  H Kunugi; S Nanko; N Takei; K Saito; RM Murray; T Hirose

  JOURNAL OF NERVOUS AND MENTAL DISEASE WILLIAMS & WILKINS 184 (9) 542 - 546 0022-3018 1996/09 [Refereed]
  
• Manic-depressive illness and tyrosine hydroxylase gene

  H Kunugi; Y Kawada; M Tatsumi; T Sasaki; S Nanko

  LANCET LANCET LTD 348 (9023) 336 - 336 0140-6736 1996/08 [Refereed]
  
• 5HT(2a) receptor T102C polymorphism and schizophrenia

  CP Clifford; DJR Nunez

  LANCET LANCET LTD 347 (9018) 1830 - 1830 0140-6736 1996/06 [Refereed]
  
• An overview of schizophrenia genetic research presented at the 1995 World Congress on Psychiatric Genetics, Cardiff

  HP Wallada; H Kunig

  SCHIZOPHRENIA RESEARCH ELSEVIER SCIENCE BV 19 (2-3) 87 - 92 0920-9964 1996/05 [Refereed]
  
• Small head circumference at birth in schizophrenia

  H Kunugi; N Takei; RM Murray; K Saito; S Nanko

  SCHIZOPHRENIA RESEARCH ELSEVIER SCIENCE BV 20 (1-2) 165 - 170 0920-9964 1996/05 [Refereed]
  
• Serotonin transporter gene polymorphism and affective disorder

  G Stober; A Heils; KP Lesch

  LANCET LANCET LTD 347 (9011) 1340 - 1341 0140-6736 1996/05 [Refereed]
  
• 精神疾患—特集 遺伝子研究の進歩と臨床応用

  功刀 浩

  治療 南山堂 78 (5) 2225 - 2228 0022-5207 1996/05
• Additional Support for Schizophrenia Linkage on Chromosomes 6 and 8: A Multicenter Study

  Dieter B. Wildenauer; Sibylle G. Schwab; Margot Albus; Joachim Hallmayer; Bernard Lerer; Wolfgang Maier; Douglas Blackwood; Walter Muir; David St Clair; Stewart Morris; Hans W. Moises; Liu Yang; Helgi Kristbjarnarson; Tomas Helgason; Claudia Wiese; David A. Collier; Peter Holmans; Jo Daniels; Mark Rees; Philip Asherson; Queta Roberts; Alastair Cardno; Maria J. Arranz; Homero Vallada; David Ball; Hiroshi Kunugi; Robin M. Murray; John F. Powell; Sin Nanko; Pak Sham; Mike Gill; Peter McGuffin; Michael J. Owen; Ann E. Pulver; Stylianos E. Antonarakis; Robert Babb; Jean-Louis Blouin; Nicola DeMarchi; Beth Dombroski; David Housman; Maria Karayiorgou; Jurg Ott; Laura Kasch; Haig Kazazian; Virginia K. Lasseter; Erika Loetscher; Hermann Luebbert; Gerald Nestadt; Carl Ton; Paula S. Wolyniec; Claudine Laurent; Michel de Chaldee; Florence Thibaut; Maurice Jay; Daniele Samolyk; Michel Petit; Dominique Campion; Jacques Mallet; Richard E. Straub; Charles J. MacLean; Stephen M. Easter; F. Anthony O'Neill; Dermot Walsh; Kenneth S. Kendler; Pablo V. Gejman; Qiuhe Cao; Elliot Gershon; Judith Badner; Ethiopia Beshah; Jing Zhang; Brien P. Riley; Swarnageetha Rajagopalan; Mpala Mogudi-Carter; Trefor Jenkins; Robert Williamson; Lynn E. DeLisi; Chad Garner; Mary Kelly; Carrie LeDuc; Lon Cardon; Jay Lichter; Tim Harris; Josephine Loftus; Gail Shields; Margarite Comasi; Antonio Vita; Angela Smith; Jay Dann; Geoff Joslyn; Hugh Gurling; Gursharan Kalsi; Jon Brynjolfsson; David Curtis; Thordur Sigmundsson; Robert Butler; Tim Read; Patrice Murphy; Andrew Chih-Hui Chen; Hannes Petursson; Bill Byerley; Mark Hoff; John Holik; Hilary Coon; Douglas F. Levinson; Derek J. Nancarrow; Raymond R. Crowe; Nancy Andreasen; Jeremy M. Silverman; Richard C. Mohs; Larry J. Siever; Jean Endicott; Lawrence Sharpe; Marilyn K. Walters; David P. Lennon; Nicholas K. Hayward; Lodewijk A. Sandkuijl; Bryan J. Mowry; Harald N. Aschauer; Kurt Meszaros; Elisabeth Lenzinger; Karoline Fuchs; Liu Yang; Angela M. Heiden; Hans W. Moises; Leonid Kruglyak; Mark J. Daly; Tara C. Matise

  American Journal of Medical Genetics Wiley-Liss Inc. 67 (6) 580 - 594 1096-8628 1996 [Refereed]
  
• A CASE OF BIPOLAR DISORDER WITH BALANCED CHROMOSOMAL TRANSLOCATION

  H KUNUGI; S NANKO; H KAZAMATSURI

  BIOLOGICAL PSYCHIATRY ELSEVIER SCIENCE PUBL CO INC 38 (2) 116 - 118 0006-3223 1995/07 [Refereed]
  
• EARLY PARENTAL LOSS AND DEPRESSIVE DISORDER IN JAPAN

  H KUNUGI; N SUGAWARA; H AOKI; S NANKO; T HIROSE; H KAZAMATSURI

  EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE SPRINGER VERLAG 245 (2) 109 - 113 0940-1334 1995/04 [Refereed]
  
• SCHIZOPHRENIA FOLLOWING IN-UTERO EXPOSURE TO THE 1957 INFLUENZA EPIDEMICS IN JAPAN

  H KUNUGI; S NANKO; N TAKEI; K SAITO; N HAYASHI; H KAZAMATSURI

  AMERICAN JOURNAL OF PSYCHIATRY AMER PSYCHIATRIC ASSOCIATION 152 (3) 450 - 452 0002-953X 1995/03 [Refereed]
  
• HEAD CIRCUMFERENCE AT BIRTH AND SCHIZOPHRENIA

  H KUNUGI; N TAKEI; S NANKO; K SAITO; H KAZAMATSURI

  BRITISH JOURNAL OF PSYCHIATRY ROYAL COLLEGE OF PSYCHIATRISTS 165 551 - 552 0007-1250 1994/10 [Refereed]
  
• LOW SERUM-CHOLESTEROL AND SUICIDE ATTEMPTS

  N TAKEI; H KUNUGI; S NANKO; H AOKI; R IYO; H KAZAMATSURI

  BRITISH JOURNAL OF PSYCHIATRY ROYAL COLLEGE OF PSYCHIATRISTS 164 702 - 703 0007-1250 1994/05 [Refereed]
  
• CHANGES OF IMMUNOLOGICAL FUNCTIONS AFTER ACUTE EXACERBATION IN SCHIZOPHRENIA

  T SASAKI; S NANKO; R FUKUDA; T KAWATE; H KUNUGI; H KAZAMATSURI

  BIOLOGICAL PSYCHIATRY ELSEVIER SCIENCE INC 35 (3) 173 - 178 0006-3223 1994/02 [Refereed]
  
• PERICENTRIC REGION OF CHROMOSOME-9 IS A POSSIBLE CANDIDATE REGION FOR LINKAGE STUDY OF SCHIZOPHRENIA

  S NANKO; H KUNUGI; T SASAKI; R FUKUDA; T KAWATE; H KAZAMATSURI

  BIOLOGICAL PSYCHIATRY ELSEVIER SCIENCE INC 33 (8-9) 655 - 658 0006-3223 1993/04 [Refereed]
  
• [Depressive disorder following personnel change--its clinical features, situational factors antecedent to recovery and treatment].

  Kunugi H

  Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica 4 95 325 - 342 0033-2658 1993 [Refereed]
  
• [Schizophrenia following prenatal exposure to influenza during second trimester].

  Kunugi H; Nanko S; Takei N; Saito K; Hayashi N; Kikumoto K; Hirai T; Kazamatsuri H

  Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica 6 95 453 - 462 0033-2658 1993 [Refereed]
  
• 胎生中期における母親のインフルエンザ感染と精神分裂病

  功刀浩

  精神神経学雑誌 95 453 - 462 1993
• 人事異動を誘因として発症したうつ病-臨床特性, 回復状況と治療について-

  功刀浩

  精神神経学雑誌 95 325 - 342 1993
• INFLUENZA AND SCHIZOPHRENIA IN JAPAN

  H KUNUGI; S NANKO; N TAKEI

  BRITISH JOURNAL OF PSYCHIATRY ROYAL COLLEGE OF PSYCHIATRISTS 161 274 - 275 0007-1250 1992/08 [Refereed]
  

Books etc

• 食生活習慣とうつ病リスク

  功刀浩 (Joint work「疾病予防・健康寿命延伸に資する栄養・食生活とは？」（津金昌一郎編）、別冊医学のあゆみ、pp.31-36.)医歯薬出版、東京 2023/11
• 薬だけに頼らずうつがみるみる遠ざかる食べ方大全

  功刀浩 (Single work)文響社 2023/06
• 美味しく食べてメンタルケア : 精神栄養学最前線

  功刀, 浩; 中央労働災害防止協会 中央労働災害防止協会 2022/04 9784805920473 15 p
• 臨床に役立つ精神疾患の栄養食事指導

  功刀, 浩; 阿部, 裕二 講談社 2021/07 9784065213254 x, 227p
• 発達障害食事・栄養・キレーション療法をご存じですか? : 症例に合った心と身体に優しい療法

  樋田, 毅; 功刀, 浩 ウェイツ 2020/02 9784904979297 201p
• 心の病を治す食事・運動・睡眠の整え方

  功刀, 浩 翔泳社 2019/01 9784798157733 159p
• 精神疾患は脳の病気か? : 向精神薬の科学と虚構

  Valenstein, Elliot S.; 功刀, 浩; 中塚, 公子 みすず書房 2018/04 9784622086987 325, xlvp
• 読めば気持ちがす～っと軽くなる本人・家族に優しい統合失調症のお話

  功刀, 浩 翔泳社 2018/01 9784798153322 159p
• こころに効く精神栄養学

  功刀, 浩 女子栄養大学出版部 2016/03 9784789554459 229p
• うつ病の毎日ごはん : 国立精神・神経医療研究センターの医師と管理栄養士が教える

  功刀, 浩; 今泉, 博文 女子栄養大学出版部 2015/04 9784789518765 103p
• うつ病 : 治療・研究の最前線

  功刀, 浩 医歯薬出版 2014/02 154p
• 精神疾患の薬物療法講義 : 研修医・コメディカルのための

  功刀, 浩 金剛出版 2013/06 9784772413152 227p
• うつ病 : 治療・研究の最前線

  功刀, 浩 医歯薬出版 2013/02 p361-511, ivp
• 図解やさしくわかる統合失調症 : 正しい理解と付き合い方

  功刀, 浩 ナツメ社 2012/08 9784816352508 175p
• 精神疾患の脳科学講義

  功刀, 浩 金剛出版 2012/07 9784772412629 204p
• 精神・神経疾患のバイオマーカーの探索と臨床応用に関する研究研究報告書

  功刀, 浩 [功刀浩] 2012/03 冊
• 精神疾患診断のための脳形態・機能検査法

  三国, 雅彦; 福田, 正人; 功刀, 浩 新興医学出版社 2012/02 9784880027302 xi, 230p
• 統合失調症の常識は本当か? : 研究と治療の最前線から

  McDonald, Colm; Schulze, Katja; Murray, Robin M.; Wright, Padraig; 功刀, 浩; 堀, 弘明 培風館 2009/07 9784563052089 xiv, 236p, 図版 [6] p
• 統合失調症100のQ&A : 苦しみを乗り越えるために

  DeLisi, Lynn E.; 功刀, 浩; 堀, 弘明 星和書店 2008/04 9784791106585 xxx, 239p
• 精神疾患は脳の病気か? : 向精神薬の科学と虚構

  Valenstein, Elliot S.; 中塚, 公子; 功刀, 浩 みすず書房 2008/02 9784622073611 325, xlvp
• ストレスと心の健康 : 新しいうつ病の科学

  Wallenstein, Gene; 功刀, 浩 培風館 2005/03 456305691X vii, 233, 11p
• 精神分裂病における神経栄養因子遺伝子変異と神経発達との関連

  功刀, 浩 [功刀浩] 1999/03 1冊

Conference Activities & Talks

• Altered circadian rhythm of activity and heart rate variability in depression

  Kunugi H

  The 101st Annual Meeting of the Physiological Society of Japan  2024/03
• Cellular phenotypes and causal candidate genes in iPSC-derived neurons of bipolar disorder family patients.

  高松 岳矢; 馬目 陽子; 當山 奏子; 柳 久美子; Dimitar Dimitrov; 李 俊錫; 赤嶺裕子; 小金渕 佳江; 長谷川 実奈美; 早川 朋子; 田冬子; 服部功太郎; 高橋智幸; 功刀 浩; 近藤 毅; 要 匡; 岡野 ジェイムス洋尚; 木村 亮介; 松下 正之

  第101回日本生理学会シンポジウム「精神疾患の分子病態解明に向けた多層的研究」北九州市 北九州国際会議場・西日本総合展示場
• 精神疾患を支える食支援

  功刀浩

  特別区職員研修所令和5年度専門研修「栄養士」  2024/02
• 精神疾患と栄養・食事・サプリメント

  功刀浩

  神戸薬科大学エクステンションセンター生涯研修支援プログラム 第52回健康食品講座（e-learning:オンデマンド配信）
• うつ病の病態と栄養学的アプローチ・ムードフード

  功刀浩

  第5回ヘルスフードアカデミックサロン（文京シビックホール）  2024/01
• うつ病の栄養学的治療

  功刀浩

  東京理科大学 医療薬学教育研究支援センター薬学ベーシックコース 薬物治療 アップトゥデート講座⑦（オンライン講演）  2024/01
• うつ病の病態仮説と治療薬

  功刀浩

  東京理科大学 医療薬学教育研究支援センター薬学ベーシックコース 薬物治療 アップトゥデート講座⑦（オンライン講演）  2024/01
• うつ病と生活習慣（病）

  功刀浩

  第57回日本成人病（生活習慣病）学会学術集会イブニングセミナー（MSD後援）  2024/01
• うつ病の栄養学的アプローチ

  功刀浩

  Meiji社内オンラインセミナー  2024/01
• 統合失調症の病態と薬物療法・栄養学的介入

  功刀浩

  第96回板薬イブニングセミナー オンライン講演 （板橋区薬剤師会、住友ファーマ共催）  2023/12
• Cellular phenotypes and causal candidate genes in iPSC-derived neurons of bipolar disorder family patients

  高松 岳矢; 馬目 陽子; 當山 奏子; 柳 久美子; 李 俊錫; 小金渕 佳江; 長谷川 実奈美; 早川 朋子; 吉田冬子; 服部功太郎; 功刀 浩; 近藤 毅; 木村 亮介; 岡野 ジェイムス洋尚; 要 匡; 松下 正之

  第46回日本分子生物学会、神戸市 神戸ポートアイランド  2023/12
• ベンゾジアゼピン受容体作動薬の処方制限は過量服薬による自殺企図を減らしたか？

  赤羽晃寿; 松村謙一; 金井理恵; 功刀浩

  第36回日本総合病院精神医学会総会  2023/11
• 精神科治療に有用な栄養学的知識と実践：うつ病を中心に

  功刀浩

  第36回日本総合病院精神医学会総会ランチョンセミナー6（ノーベルファーマ、メディパルホールディングス共催）  2023/11
• 活力ある生活を維持するための習慣：食生活を中心に

  功刀浩

  さいたま市教育委員会学校給食部門講演会(さいたま市プラザノース)  2023/11
• メンタルヘルスによい食と栄養～リカバリーへの栄養学的アプローチ～

  功刀浩

  リカバリー全国フォーラム2023（地域精神保健福祉機構 COHMBO主催）オンライン配信  2023/11
• うつ病と腸内マイクロバイオーム

  功刀浩

  第45回日本生物学的精神医学会年会シンポジウム10、万国津梁館、沖縄  2023/11
• 精神疾患と腸-相関・代謝

  功刀浩

  第45回日本生物学的精神医学会年会ランチョンセミナー２（Meijiseikaファルマ共催）万国津梁館、沖縄  2023/11
• 栄養とメンタルヘルス

  功刀浩

  メンタルヘルスマネジメント概論 （2023年度早稲田大学秋学期・講義）  2023/11
• 精神栄養学

  功刀浩

  令和5年度 広島県栄養士会生涯教育研修会、2023年10月22日、オンライン開催  2023/10
• 深刻な自殺企図を行なったが、てんかん発作後に自殺念慮が消失した１例-低コルチゾル血症関与の可能性-

  藤井亮佑、小方茂弘、松村謙一、渡邊由香子、赤羽晃寿、菅野道、功刀浩

  第42回躁うつ病の薬理・生化学的研究懇話会、皆生グランドホテル天水、鳥取  2023/10
• こころの問題を抱える方の食事相談とは

  功刀浩

  令和5年度千葉県市原保健所給食施設指導事業給食施設栄養士研修会  2023/10
• こころの疲れ（メンタル不調）を予防・改善するための食事・運動・睡眠

  功刀浩

  令和5年度三鷹市民健康講座、連雀コミュニティーセンター  2023/10
• うつ病の病態と栄養学的アプローチ

  功刀浩

  西多摩医師会学術講演会（西多摩医師会、住友ファーマ、ヴィアトリス製薬共催）  2023/09
• スポーツ活動と精神面のメンズヘルス

  功刀 浩

  第23回日本メンズヘルス医学会  2023/09
• うつ病の病態、治療における腸内細菌叢の役割

  功刀 浩

  第53回日本神経精神薬理学会年会  2023/09
• ケイパビリティ哲学一かけがえのない個人の尊厳と能力を尊重する先端総合科学の探究

  後藤玲子; 功刀浩; 荒巻恵子; 渡辺浩平; 菊池正; リネペ・アンドレ; 小西杏奈; 伊藤寛了; 落合亮; 落合宏; 中山京子; 蔡薰婕; 松元健二; 中込和幸; 神林龍; 徳岡誠人

  第6回帝京大学研究交流シンポジウム  2023/08
• ヒトにおける薬物の脳移行性予測システムの開発

  黒澤俊樹、久保義行、出口芳春、功刀浩、頃安貞利、池俣吉人

  第6回帝京大学研究交流シンポジウム  2023/08
• 心理専門職の職業的発達プロセス―コンピテンシーと個別課題との関連―

  元永拓郎; 笠井さつき; 橋本貴裕; 海野有希; 功刀浩; 齋藤正範

  第6回帝京大学研究交流シンポジウム  2023/08
• うつ病と腸内細菌

  功刀浩

  第38回日本乾癬学会学術集会、グランドニッコー東京  2023/08
• ストレス、恐怖記憶、PTSDの神経基盤：扁桃体を中心に

  功刀浩

  第22回トラウマティックストレス学会  2023/08
• ライフスタイルと女性のメンタルヘルス

  功刀浩

  城北WEBセミナー（MSD㈱主催）  2023/07
• うつ病の栄養学的アプローチ

  功刀浩

  精神栄養学講演会（Meijiseikaファルマ主催）  2023/07
• うつ病への栄養学的アプローチ

  功刀 浩

  第20回日本うつ病学会総会、第39回日本ストレス学会・学術総会  2023/07
• うつ病の栄養療法の効果

  功刀浩

  第20回日本うつ病学会総会、第39回日本ストレス学会・学術総会  2023/07
• 精神科治療に有用な栄養学的知識：うつ病を中心に

  功刀浩

  富山県精神科医会学術講演会（ノーベルファーマ ㈱ 共催）  2023/07
• うつ病と現代のライフスタイル～食、運動、睡眠、働き方～

  功刀 浩

  帝京大学経済学部人間学基礎セミナー  2023/06
• 功刀浩：うつ病によい食生活・運動・睡眠

  功刀浩

  藤沢市保健所・藤沢病院企画 うつ病当事者・家族支援事業 【うつ病セミナー】  2023/06
• 気分障害と腸内細菌叢

  功刀浩

  第64回日本神経学会学術大会  2023/05
• うつ病と腸内細菌

  功刀浩; 相澤恵美子

  第23階腸内細菌学会  2019/06
• 脳とこころに効く！食生活習慣の知識

  功刀浩

  桜美林学園学生相談室外部講師招聘講演会  2019/05
• 双極性障害におけるＰＵＦＡと炎症・ＦＡＤＳ遺伝子・食生活との関連

  古賀賀恵; 小倉淳; 吉田冬子; 相澤恵美子; 功刀浩

  第73回日本栄養・食糧学会大会  2019/05
• ラウリン酸はアストロサイトを介してシナプス成熟を促進する

  中島進吾; 功刀浩

  第73回日本栄養・食糧学会大会  2019/05
• うつ病とアミノ酸

  功刀浩

  第73回日本栄養・食糧学会大会シンポジウム「疾病とアミノ酸代謝：基礎的治験から臨床データまで」  2019/05
• 精神疾患（統合失調症やうつ病等）のマーカー研究

  功刀浩

  「個別化医療に向けたバイオマーカー実用化技術に関する検討会」第3回：精神疾患、神経変性疾患地用や医薬品副作用における個別化技術開発の方向性について  2019/03
• うつ病の予防と治療〜食事・運動などのライフスタイル改善を中心に〜

  功刀浩

  産業衛生技術部会研修会  2019/03
• 精神科で行われる生化学検査

  功刀浩

  東京精神科病院協会栄養部門研修会  2019/03
• 多目的コホート研究既存データを用いたメンタルヘルス研究

  功刀浩

  電子化医療情報を活用した疾患横断的コホート研究情報基盤整備事業 平成30年度シンポジウム ６ＮＣ連携による疾患横断的コホート研究の推移と健康寿命延伸に向けて  2019/03
• 心の健康を保つ職場と食生活習慣

  功刀浩

  日本うつ病センター 自殺対策シンポジウム  2019/02
• うつ病や統合失調症の治療に役立つ食事と生活習慣

  功刀浩

  川崎市あやめ会H30年度公開講座  2019/02
• 心の健康を保つ食生活習慣

  功刀浩

  中央労働災害防止協会平成30年度心の健康づくりシンポジウム「健康的な生活習慣による心の健康づくり」  2019/02
• 沖縄県の双極性障害多発家系を用いた疾患関連ゲノム変異の探索

  高松岳矢; 柳久美子; 小金渕佳江; 李俊錫; 原田綾乃; 伊佐睦美; 服部功太郎; 功刀浩; 近藤毅; 木村亮介; 要匡; 松下正之

  第40回沖縄精神神経学会  2019/02
• 多層的オミックス解析による、がん、精神疾患、腎疾患を対象とした医療技術開発：（疾患４）精神疾患の治療標的分子の同定と新たな治療法開発

  功刀浩

  国立研究開発法人日本医療研究開発機構(AMED) 創薬基盤研究シンポジウム  2019/01
• 精神疾患における血漿中オレキシン濃度と臨床症状との関連

  土嶺章子; 服部功太郎; 太田深秀; 秀瀬真輔; 寺石俊也; 篠山大明; 堀弘明; 野田隆政; 吉田寿美子; 吉田冬子; 功刀浩

  精神・神経疾患研究開発費（30-7）「精神・神経医療研究センターにおけるバイオバンクの統合的管理と利活用拡大のための基盤研究」(主任研究者:後藤雄一)平成30年度 班会議  2019/01
• うつ病の病態と栄養学的問題

  功刀浩

  第22回日本病態栄養学会年次学術集会 シンポジウム「うつ病、統合失調症などの精神疾患の病態と栄養管理  2019/01
• 心の健康を保つための食事と生活習慣

  功刀浩

  ホープス社内総会講演会  2018/12
• 発達障害バイオマーカーの開発

  功刀浩

  精神・神経疾患研究開発費（29?6）「発達障害の治療法の確立をめざすトランスレーショナルリサーチ」(主任研究者:一戸紀孝)平成30 年度 班会議  2018/12
• 精神疾患における脳脊髄液中マトリックスメタロプロテアーゼの変化

  大盛航; 服部功太郎; 岡田麻美; 梶谷直人; 安部裕美; 板垣圭; 功刀浩; 岡本泰昌; 竹林実

  広島精神神経学会  2018/12
• 精神疾患患者の腸内細菌叢に関する検討．シンポジウム「腸脳相関と神経精神薬理」（オーガナイザー功刀浩）

  功刀浩

  2018/11
• うつ病の有望なバイオマーカーシンポジウム「気分障害のアンメットニーズ」（オーガナイザー住吉太幹）

  功刀浩

  第28回日本臨床精神神経薬理学会、第48回日本神経精神薬理学会合同年会  2018/11
• 「働く」を支えるこころの栄養学

  功刀浩

  平成30年度世田谷区障害者就労支援センターしごとねっと研修プログラム  2018/11
• うつ病への栄養学的アプローチ

  功刀浩

  第28回多摩西部地域精神科診療所懇話会特別講演  2018/10
• 心の病に効く食生活 -精神科栄養学-

  功刀浩

  第11回城東プシケフォーラム  2018/10
• うつ病患者の腸内細菌叢に関する研究

  功刀浩

  第9回ヤクルト代田カンファレンス  2018/10
• うつ病における脳脊髄液中モノアミン代謝物濃度のメタアナリス

  小川眞太朗; 土嶺章子; 功刀浩

  第37回躁うつ病の薬理・生化学的研究懇話会  2018/10
• 精神科患者と健常者の全身持久性体力と脳画像、心理指標との関連の研究

  石田一希; 太田深秀; 松尾淳子; 平石萌子; 秀瀬真輔; 寺石俊也; 吉田冬子; 諏訪部和也; 征矢英昭; 功刀浩

  第37回躁うつ病の薬理・生化学的研究懇話会  2018/10
• 大うつ病における脳脊髄液中コルチトロピン放出ホルモン濃度

  石渡小百合; 服部功太郎; 篠山大明; 宮川友子; 横田悠季; 松村亮; 功刀浩

  第37回躁うつ病の薬理・生化学的研究懇話会  2018/10
• 反復拘束ストレス深によるうつ病様行動に対するマウス系統とストレス暴露期間の影響

  土嶺章子; 千葉秀一; 吉村文; 鈴木仁美; 大橋一徳; 中島進吾; 惣谷和広; 功刀浩

  第37回躁うつ病の薬理・生化学的研究懇話会  2018/10
• 腸内フローラとうつ病、自閉症

  功刀浩

  日本食品免疫学会 第13回産官学交流委員会主催セミナー  2018/10
• 精神栄養学〜うつ病を中心に〜

  功刀浩

  第56回全国大学保健管理研究集会教育講演２  2018/10
• うつ病治療における食生活・栄養と運動

  功刀浩

  第２回うつ病の治療プログラムを考える〜寛解そして真のrecoveryを目指して〜  2018/10
• 服薬だけに頼らない精神疾患の改善法：食事と運動を中心にした生活習慣について

  功刀浩

  新潟県三条市精神保健福祉フォーラム  2018/09
• ケトン食を用いた認知機能その他の脳機能改善効果について

  功刀浩

  第507回医療技術セミナー“スキルアップ”  2018/09
• 精神栄養学〜精神疾患のメカニズムおよび食と精神疾患との関係〜

  功刀浩

  日本栄養評議会第92回勉強会  2018/09
• 統合失調症のメタボローム解析

  功刀浩

  第40回日本生物学的精神医学会/第61回日本神経化学大会  2018/09
• うつ病の栄養・運動療法

  功刀浩

  第15回日本うつ病学会総会シンポジウム１「多様化するうつ病治療：適応、利点、問題点、実現可能性」  2018/07
• 統合失調症の薬物療法とアドヒアランス

  功刀浩

  2018/07
• 脳脊髄液試料を活用した認知症の分子病態と脳画像に関する研究

  功刀浩; 服部功太郎; 土本瑶子; 太田深秀

  国立精神・神経医療研究センター精神・神経疾患研究開発費「認知症・神経変性疾患の病態解明と治療・介護・予防法開発」（主任研究者水澤英洋）班会議  2018/07
• 栄養成分、特に食肉成分と精神疾患について

  功刀浩

  食肉と健康を考えるフォーラム委員会  2018/07
• うつ病患者の性機能障害に関連する２,３の事柄

  功刀浩

  第18回日本Men's Health 医学会シンポジウム「メンズヘルスとメンタルヘルス」  2018/07
• 緑茶成分テアニンの多彩な向精神作用について

  功刀浩

  第33回老化促進モデルマウス(SAM)学会学術大会  2018/07
• 気分障害先端治療センターによる多次元うつ病治療の試み

  功刀浩

  メンタルヘルスセミナー  2018/06
• 科学的に解き明かすうつ病と食事・運動の関係〜回復を助ける生活習慣とは〜

  功刀浩

  光が丘保健相談所 精神講演会  2018/06
• ECTの分子マーカーの探索/委員会シンポジウム21臨床におけるＥＣＴの疑問

  服部功太郎; 野田隆政; 秀瀬真輔; 吉田寿美子; 功刀浩

  第114回日本精神神経学会総会  2018/06
• うつ病における神経炎症とトリプトファンーキヌレニン経路の役割、シンポジウム「よくわかるうつ病脳科学入門

  功刀浩

  第114回日本精神神経学会総会  2018/06
• 中鎖脂肪酸を含むケトン食によるアルツハイマー病患者の認知機能改善効果の検討

  松尾淳子; 太田深秀; 石田一希; 堀弘明; 高野晴成; 横井優磨; 吉田寿美子; 芦田欣也; 中村健太郎; 橋毅, 功刀浩

  第114回日本精神神経学会学術総会  2018/06
• 精神疾患に対する栄養学的アプローチ

  功刀浩

  心とからだの栄養セミナー（全国精神科栄養士協議会・株式会社ヤクルト本社首都圏支店共催）  2018/06
• 精神疾患のサイコメタボリズム：肥満や腸内細菌を中心に

  功刀浩

  サイコメタボリズムクラブ  2018/06
• うつ病の栄養学的アプローチ

  功刀浩

  気分障害先端治療センター市民公開講座  2018/06
• うつ病における食ー脳軸の解明と新たな治療法の開発

  功刀浩

  平成30年度うつ病・双極性障害等の克服研究チーム分科会  2018/06
• 精神疾患におけるメタボリック症候群、栄養不足へのアプローチ

  功刀浩

  第8回精神疾患の身体合併症を考える会  2018/05
• 精神疾患における脳脊髄液中matrix metalloproteinasesの検討

  大盛航; 服部功太郎; 岡田麻美; 梶谷直人; 安部裕美; 板垣圭; 功刀浩; 竹林実

  第5回サイコグリア研究会  2018/05
• 精神疾患への栄養学的アプローチ

  功刀浩

  安房保健所管内栄養士会研修会  2018/05
• 認知機能低下を予防する機能性食品〜ケトン食を中心に〜

  功刀浩

  ヘルスフードエキスポ「認知機能低下予防と機能性食品素材セミナー」  2018/05
• 心の病気と食生活・栄養

  功刀浩

  ソーシャルユニバーシティ健康サポート薬局のための栄養講座  2018/05
• 心の病に効く食事と運動

  功刀浩

  中央区日本橋保健所センター精神保健講演会  2018/02
• うつ病と食事、栄養学的アプローチ

  功刀浩

  第27回精神科診療所デイケア研究会  2018/01

MISC

• 精神疾患と腸内細菌叢のかかわりを探る

  功刀浩(監修)  Trends in Psychiatric Science  1  -3  2024/02  [Invited]
  
• この書籍から学んだこと：精神科医による書籍紹介

  功刀浩  CNS情報Plus  31-  8  -8  2024/02  [Invited]
  
• ストレスでうつ病になるのはどうしてですか？

  功刀 浩  CLINICAL NEUROSCIENCE  41-  (10)  1375  -1375  2023/10  [Invited]
  
• うつを予防・改善するための食生活

  功刀 浩  中学保健ニュース  (1886)  2023/07  [Invited]
  
• 心の健康を支える食習慣

  功刀 浩  中学保健ニュース  (1886)  2023/07
• Hypothalamic-pituitary-adrenal axis and renin-angiotensin-aldosterone system in adulthood PTSD and childhood maltreatment history(タイトル和訳中)

  筧 亮子; 堀 弘明; 吉田 冬子; 伊藤 真利子; 林 明明; 丹羽 まどか; 成田 恵; 井野 敬子; 今井 理紗; 篠山 大明; 加茂 登志子; 功刀 浩; 金 吉晴  国立精神・神経医療研究センター精神保健研究所年報  (36)  204  -204  2023/07
• 【脳腸相関UPDATE-疾患の予防と健康長寿のための食・栄養・腸環境】(Part3)脳腸相関と食・栄養 地中海食

  功刀 浩  臨床栄養  142-  (6)  983  -989  2023/05
• 気分障害におけるストレス要因を規定する栄養・腸内環境の解明

  功刀 浩  先進医薬研究振興財団研究成果報告集  2022年度-  14  -16  2023/03
• うつ病とアミノ酸

  功刀 浩  アミノ酸研究  16-  (1)  41  -45  2023/03
• 神経疾患における欧米食とケトン食：その違いとは？

  橋本みどり; 功刀浩(翻; 板倉弘重  栄養学レビュー  80-  (8-10)  188  -206  2023  [Invited]
  
• うつ病と栄養について

  功刀浩  CNS情報Plus  27-  8  -8  2023/01  [Invited]
  
• アルツハイマー型認知症の病型診断における髄液検査が有用だった1例

  種田 将; 赤羽 晃寿; 渡邊 公聡; 金田 渉; 秀瀬 真輔; 佐藤 研一; 功刀 浩  精神神経学雑誌  125-  (1)  85  -85  2023/01
• 気分障害と腸内フローラ 新たな治療の可能性とメカニズム

  功刀 浩  日本心療内科学会誌  26-  (別冊)  140  -140  2022/11
• うつ病患者に対する栄養食事指導 精神科外来での実践に関する後方視調査から

  宮本 佳世子; 笠原 康平; 功刀 浩  New Diet Therapy  38-  (2)  213  -213  2022/09
• 統合失調症入院患者を対象とした高尿酸血症リスク因子に関する探索的後方視研究

  笠原 康平; 宮本 佳世子; 大森 まゆ; 大町 佳永; 功刀 浩  New Diet Therapy  38-  (2)  214  -214  2022/09
• 男性の性腺機能低下症ガイドライン2022

  堀江 重郎; 天野 俊康; 石井 智弘; 井手 久満; 伊藤 直樹; 岩月 正一郎; 上芝 元; 大山 力; 小川 純人; 蔭山 和則; 方波見 卓行; 川戸 佳; 菅野 潤子; 功刀 浩; 重原 一慶; 周東 孝浩; 白石 晃司; 白川 智也; 鈴木 和浩; 高岡 正和; 高橋 裕; 竹石 恭知; 立花 修; 田邉 真紀人; 辻村 晃; 鳥居 俊; 西岡 宏; 長谷川 奉延; 畠山 真吾; 濱島 崇; 濱野 逸人; 福井 道明; 福岡 秀規; 松井 克之; 松下 一仁; 溝上 敦; 村元 啓仁; 八木 弘子; 安井 孝周; 柳瀬 敏彦; 義久 精臣; 男性の性腺機能低下症ガイドライン作成委員会, 一般社団法人日本内分泌学会, 一般社団法人日本メンズヘルス医学会  日本内分泌学会雑誌  98-  (Suppl.)  np1  -140  2022/07
• 男性の性腺機能低下症ガイドライン2022

  堀江 重郎; 天野 俊康; 石井 智弘; 井手 久満; 伊藤 直樹; 岩月 正一郎; 上芝 元; 大山 力; 小川 純人; 蔭山 和則; 方波見 卓行; 川戸 佳; 菅野 潤子; 功刀 浩; 重原 一慶; 周東 孝浩; 白石 晃司; 白川 智也; 鈴木 和浩; 高岡 正和; 高橋 裕; 竹石 恭知; 立花 修; 田邉 真紀人; 辻村 晃; 鳥居 俊; 西岡 宏; 長谷川 奉延; 畠山 真吾; 濱島 崇; 濱野 逸人; 福井 道明; 福岡 秀規; 松井 克之; 松下 一仁; 溝上 敦; 村元 啓仁; 八木 弘子; 安井 孝周; 柳瀬 敏彦; 義久 精臣; 男性の性腺機能低下症ガイドライン作成委員会, 一般社団法人日本内分泌学会, 一般社団法人日本メンズヘルス医学会  日本内分泌学会雑誌  98-  (Suppl.)  np1  -140  2022/07
• 排泄障害への牛車腎気丸服用後にADLと認知機能が改善したウェルニッケ・コルサコフ症候群(WKS)の1例

  野村 芳子; 秀瀬 真輔; 金井 理恵; 押久保 岳; 渡邊 由香子; 赤羽 晃寿; 栃木 衛; 功刀 浩  精神神経学雑誌  124-  (4付録)  S  -388  2022/04
• 精神疾患マネジメントをめぐる身体科医や多職種との連携・協働 神経精神症状を伴うSLE(NPSLE)に対する診療科連携による診断・治療への取り組み

  岩田 慈; 藤田 悠哉; 秀瀬 真輔; 石渡 小百合; 服部 功太郎; 池ノ内 篤子; 功刀 浩; 吉村 玲児; 田中 良哉  精神神経学雑誌  124-  (4付録)  S  -657  2022/04
• 大うつ病性障害および統合失調症における脳脊髄液リゾホスファチジン酸ドコサヘキサエン酸(LPA-DHA)の減少

  大盛 航; 可野 邦行; 服部 功太郎; 梶谷 直人; 岡田 麻美; 朴 秀賢; 功刀 浩; 青木 淳賢; 竹林 実  精神神経学雑誌  124-  (4付録)  S  -641  2022/04
• 双極性障害家系ハプロタイプにおけるミトコンドリア代謝制御遺伝子Xの発現低下

  高松 岳矢; 馬目 陽子; 柳 久美子; 小金渕 佳江; 當山 奏子; 李 俊錫; 長谷川 実奈美; 服部 功太郎; 功刀 浩; 近藤 毅; 岡野 ジェイム洋尚; 木村 亮介; 要 匡; 松下 正之  日本脳科学会プログラム・抄録集  48回-  A  -1  2021/12
• 炎症と記憶に着目したPTSDの遺伝学的検討

  堀弘明; 吉田冬子; 伊藤真利子; 林明明; 丹羽まどか; 井野敬子; 井野敬子; 今井理紗; 今井理紗; 小川成; 関口敦; 加茂登志子; 功刀浩; 金吉晴  国立精神・神経医療研究センター精神保健研究所研究報告会プログラム・抄録集(Web)  32nd-  2021
• Genetic study of Okinawan large pedigree with bipolar disorder and recurrent depressive disorder: the integrated approach of genome sequencing and induced pluripotent stem cell technology

  高松岳矢; 柳久美子; 馬目陽子; 小金渕佳江; 李俊錫; 當山奏子; 佐藤万仁; DIMITAR Dimitrov; 原(宮内)央子; 長谷川実奈美; 早川朋子; 近藤毅; 服部功太郎; 服部功太郎; 功刀浩; 高橋智幸; 岡野ジェイムス洋尚; 木村亮介; 要匡; 松下正之  日本神経精神薬理学会プログラム・抄録集  50回・42回・4回-  217  -217  2020/08
• 心的外傷後ストレス障害の女性患者における炎症マーカー

  今井理紗; 今井理紗; 堀弘明; 伊藤真利子; 林明明; 丹羽まどか; 井野敬子; 井野敬子; 小川成; 関口敦; 功刀浩; 明智龍男; 加茂登志子; 金吉晴  国立精神・神経医療研究センター精神保健研究所研究報告会プログラム・抄録集(Web)  31st-  2020
• Genome-wide association study detected novel susceptibility genes for schizophrenia and shared trans-populations/diseases genetic effect(和訳中)

  池田 匡志; 高橋 篤; 鎌谷 洋一郎; 桃沢 幸秀; 齋藤 竹生; 近藤 健治; 島崎 愛夕; 川瀬 康平; 作佐部 太也; 岩山 佳美; 豊田 倫子; 和久田 智靖; 菊池 充; 金原 信久; 山森 英長; 安田 由華; 渡部 雄一郎; 保谷 智史; アレクシッチ ブランコ; 久島 周; 新井 平伊; 高木 学; 服部 功太郎; 功刀 浩; 岡久 祐子; 大沼 徹; 尾崎 紀夫; 染矢 俊幸; 橋本 亮太; 吉川 武男; 久保 充明; 岩田 仲生  日本臨床精神神経薬理学会・日本神経精神薬理学会合同年会プログラム・抄録集  29回・49回-  124  -124  2019/10
• 自閉症感受性遺伝子Auts2変異により引き起こるシナプス形成障害およびマウス行動異常の病態解析

  堀啓; 山城邦比古; 永井拓; WEI Shan; 江草早紀; 嶋岡可純; 郷康宏; 辰本将司; 菅野康太; 坂本亜沙美; 阿部学; 崎村健司; 惣谷和宏; 功刀浩; 山田清文; 星野幹雄  日本分子生物学会年会プログラム・要旨集(Web)  42nd-  2019
• ストレス脆弱性についての表現型と末梢血トランスクリプトームの統合解析

  堀 弘明; 中村 誠二; 吉田 冬子; 寺石 俊也; 篠山 大明; 太田 深秀; 服部 功太郎; 金 吉晴; 樋口 輝彦; 功刀 浩  臨床薬理の進歩  (39)  140  -152  2018/06
• PTSD女性患者における認知機能

  堀 弘明; 伊藤 真利子; 林 明明; 丹羽 まどか; 井野 敬子; 今井 理紗; 小川 成; 関口 敦; 功刀 浩; 加茂 登志子; 金 吉晴  国立精神・神経医療研究センター精神保健研究所年報  (30)  229  -229  2017/10
• PTSD女性患者における炎症マーカー(Inflammatory markers in adult women with posttraumatic stress disorder)

  堀 弘明; 伊藤 真利子; 林 明明; 丹羽 まどか; 井野 敬子; 今井 理紗; 小川 成; 関口 敦; 功刀 浩; 加茂 登志子; 金 吉晴  日本生物学的精神医学会・日本神経精神薬理学会合同年会プログラム・抄録集  39回・47回-  175  -175  2017/09
• PTSD女性患者における炎症マーカー(Inflammatory markers in adult women with posttraumatic stress disorder)

  堀 弘明; 伊藤 真利子; 林 明明; 丹羽 まどか; 井野 敬子; 今井 理紗; 小川 成; 関口 敦; 功刀 浩; 加茂 登志子; 金 吉晴  日本生物学的精神医学会・日本神経精神薬理学会合同年会プログラム・抄録集  39回・47回-  175  -175  2017/09
• 精神疾患の脳脊髄液マーカー (特集 精神疾患のバイオマーカー)

  功刀 浩  分子精神医学  17-  (3)  170  -176  2017/07
• 【精神疾患のバイオマーカー】血液メタボローム解析による、うつ重症度・自殺念慮のバイオマーカー開発

  加藤 隆弘; 瀬戸山 大樹; 橋本 亮太; 功刀 浩; 服部 功太郎; 康 東天; 神庭 重信  分子精神医学  17-  (3)  199  -205  2017/07
• Potential role of ketamine in treatment resistant depression

  功刀 浩  精神科 = Psychiatry  30-  (6)  513  -518  2017/06
• うつ病患者における血清および脳脊髄液中のAutotaxin濃度に関する予備的研究

  板垣圭; 柴崎千代; 大盛航; 梶谷直人; 安部裕美; 岡田麻美; 服部功太郎; 吉田寿美子; 功刀浩; 竹林実  日本精神神経学会総会プログラム・抄録集  113th-  (2017特別号)  S301  -S301  2017/06
• 精神医学のフロンティア メランコリー型の特徴を伴う大うつ病性障害と非定型の特徴を伴う大うつ病性障害の白質障害の違い

  太田 深秀; 野田 隆政; 佐藤 典子; 服部 功太郎; 堀 弘明; 篠山 大明; 寺石 俊也; 長島 杏奈; 大部 聡子; 樋口 輝彦; 功刀 浩  精神神経学雑誌 = Psychiatria et neurologia Japonica  119-  (5)  295  -302  2017
• Psychotropic effects of a green tea ingredient, L-theanine

  功刀 浩; 太田 深秀; 若林 千里; 秀瀬 真輔; 小澤 隼人; 大久保 勉  日本生物学的精神医学会誌 = Japanese journal of biological psychiatry  27-  (4)  177  -181  2016/12
• The psychiatric characteristics of evacuees from Fuskushima prefecture in Kitaibaraki city after the Great East Japan Earthquake

  佐藤 晋爾; 石田 一希; 服部 功太郎; 太田 深秀; 内田 和彦; 功刀 浩  臨床精神医学  45-  (11)  1457  -1464  2016/11
• 精神科領域の用語解説 キヌレニン経路

  寺石 俊也; 功刀 浩  分子精神医学  16-  (4)  273  -275  2016/10
• Increased cerebrospinal fluid fibrinogen levels in major depressive disorder replicated in a larger sample set

  K. Hattori; D. Sasayama; S. Hidese; T. Miyakawa; M. Ota; H. Hori; S. Yoshida; Y. Goto; H. Kunugi  EUROPEAN NEUROPSYCHOPHARMACOLOGY  26-  S403  -S404  2016/10
• Involvement of hypothalamic-adrenal-pituitary axis in the mechanism of transcriptome-wide identified differentially expressed genes for depression

  H. Hori; D. Sasayama; T. Teraishi; N. Yamamoto; S. Nakamura; M. Ota; K. Hattori; Y. Kim; T. Higuchi; H. Kunugi  EUROPEAN NEUROPSYCHOPHARMACOLOGY  26-  S199  -S200  2016/10
• Round Table Discussion うつ病概念を再考する

  岩田 仲生; 岡本 泰昌; 功刀 浩; 加藤 隆弘  精神科臨床legato  2-  (4)  168  -176  2016/10
• うつ病バイオマーカーとしてのリゾホスファチジン酸の可能性

  後藤 玲央; 山田 美佐; 斎藤 顕宜; 服部 功太郎; 功刀 浩; 樋口 輝彦; 山田 光彦  国立精神・神経医療研究センター精神保健研究所年報  (29)  246  -246  2016/10
• Altered balance between monoamine metabolites in human cerebrospinal fluid with major depressive disorder.

  Hyung Shin Yoon; Kotaro Hattori; Hiroshi Kunugi; Shintaro Ogawa; Miho Ota; Daimei Sasayama; Toyisha Teraishi  INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY  19-  133  -134  2016/06
• Evaluation of plasma and cerebrospinal fluid G72 protein levels and their correlations with psychiatric symptoms in schizophrenia and major depression

  Sayuri Ishiwata-Matsushima; Kotaro Hattori; Hiroshi Kunugi; Ryo Matsumura; Tomoko Miyakawa; Toru Nishikawa; Daimei Sasayama; Toshiya Teraishi; Yuuki Yokota  INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY  19-  244  -245  2016/06
• Reduced cerebrospinal fluid ethanolamine concentration in major depressive disorder

  Shintaro Ogawa; Kotaro Hattori; Teruhiko Higuchi; Hiroaki Hori; Hiroshi Kunugi; Ryo Matsumura; Junko Matsuo; Nobutaka Motohashi; Takamasa Noda; Yoshiaki Ohashi; Miho Ota; Daimei Sasayama; Hajime Sato; Toshiya Teraishi; Yuki Yokota; Sumiko Yoshida  INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY  19-  118  -119  2016/06
• Altered protein patterns in cerebrospinal fluid of psychiatric disorders

  Kotaro Hattori; Miho Ota; Hiroshi Kunugi  INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY  19-  12  -12  2016/06
• Effect of single ketogenic diet containing medium chain triglycerides on cognitive functions in elderly adults

  Junko Matsuo; Kinya Ashida; Kotaro Hattori; Hiroshi Kunugi; Miho Ota; Takeshi Takahashi; Toyisha Teraishi; Hidekazu Tonouchi; Fuyuko Yoshida  INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY  19-  266  -266  2016/06
• Major depressive disorder and initial insulin hyposecretion in oral glucose tolerance test

  E. Aizawa; S. Yoshida; S. Tajima; K. Hattori; K. Segawa; H. Kunugi  INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY  19-  128  -128  2016/06
• Increased cerebrospinal fluid fibrinogen delineates a subgroup of major depressive disorder

  K. Hattori; M. Ota; S. Yoshida; Y. Goto; H. Kunugi  EUROPEAN NEUROPSYCHOPHARMACOLOGY  25-  S389  -S389  2015/09
• 精神疾患における客観的な補助診断法の最前線 うつ病の病態を反映する血中バイオマーカーの開発・実用化研究

  神庭 重信; 尾崎 紀夫; 橋本 亮太; 功刀 浩; 服部 功太郎; 清水 栄司; 加藤 忠史; 加藤 隆弘  日本生物学的精神医学会・日本神経精神薬理学会合同年会プログラム・抄録集  37回・45回-  143  -143  2015/09
• Round Table Discussion 気分障害における認知機能障害

  住吉 太幹; 功刀 浩; 松尾 幸治; 武島 稔  精神科臨床legato  1-  (2)  36  -43  2015/07
• Dietary and nutritional risk factors for depression

  功刀 浩  臨床精神医学  44-  (4)  513  -519  2015/04
• クルクミンとうつ病 (特集 食品と疾病 : クルクミン)

  功刀 浩; 古賀 賀恵  Functional food : 機能性食品の基礎から臨床へ  9-  (1)  14  -17  2015
• 自閉症スペクトラム障害の最適予後のための早期介入に関する研究

  神尾陽子; 高橋秀俊; 石飛信; 功刀浩; 馬塚れい子; 齊藤卓弥; 原口英之; 野中俊介; 中鉢貴行; 小松佐穂子; 荻野和雄; 望月由紀子; 櫻井由香; 浅野路子; STICKLEY Andrew; 三宅篤子; 飛松省三; 萩原綱一; 廣永成人; 米田英嗣; 福田早苗; 飯田悠佳子; 松尾淳子; 吉田冬子; 篠山大明; 太田深秀; 小坂浩隆; 平谷美智夫; 宮崎健祐; 西海枝洋子; 山根直人; 神長伸幸; 秋元頼孝; 近藤綾子; 近藤綾子; 成重竜一郎; 澤谷篤; 柳生一自  精神・神経疾患研究開発費による研究報告集(2年度班・初年度班) 平成26年度  161  -171  2015
• 睡眠医療プラットフォームPASMを用いて実施する臨床研究 ネットワーク,運用システム,リソースの構築に関する研究

  三島和夫; 肥田昌子; 亀井雄一; 功刀浩; 栗山健一; 古澤嘉彦; 伊藤洋; 清水徹男; 井上雄一; 内村直尚; 高橋正也; 角谷寛; 中崎恭子; 綾部直子; 元村祐貴; 北村真吾; 大沢知隼; 木村綾乃; 堀弘明; 古賀賀恵; 吉池卓也; 池田大樹; 小曽根基裕; 神林崇; 草薙宏明; 佐川洋平; 小林美奈; 碓氷章; 伊東若子; 中島俊; 小鳥居望; 比江嶋啓至; 森裕之; 和佐野研二郎; 大島勇人  精神・神経疾患研究開発費による研究報告集(2年度班・初年度班) 平成26年度  172  -194  2015
• POSSIBLE ASSOCIATION BETWEEN ITIH3 GENE POLYMORPHISM AND SCHIZOPHRENIA IN A JAPANESE POPULATION

  Daimei Sasayama; Hiroaki Hori; Toshiya Teraishi; Masahiko Tatsumi; Kotaro Hattori; Miho Ota; Teruhiko Higuchi; Hiroshi Kunugi  SCHIZOPHRENIA RESEARCH  153-  S362  -S362  2014/04
• 気分障害患者を対象とした5時間耐糖能試験における血糖変動の予備的検討

  村木 悦子; 横田 悠季; 服部 功太郎; 瀬川 和彦; 功刀 浩; 吉田 寿美子  日本病態栄養学会誌  17-  (Suppl.)  S  -173  2013/12
• 精神医学のフロンティア MRIによる女性統合失調症患者と女性健常群との判別分析

  太田 深秀; 佐藤 典子; 石川 正憲; 堀 弘明; 篠山 大明; 服部 功太郎; 寺石 俊也; 大部 聡子; 中田 安弘; 根本 清貴; 守口 善也; 橋本 亮太; 功刀 浩  精神神経学雑誌  115-  (12)  1171  -1177  2013/12
• Hypothalamic-pituitary-adrenal axis function and subtypes of depression

  功刀 浩; 堀 弘明  臨床精神医学  42-  (8)  991  -998  2013/08
• 被災地におけるうつ症状と食事・栄養 北茨城元気づくりプロジェクトから

  功刀 浩; 村木 悦子; 相澤 恵美子; 石田 一希; 太田 深秀; 服部 功太郎; 佐藤 晋爾; 朝田 隆  臨床栄養  123-  (1)  12  -13  2013/07
• 東日本大震災後の北茨城市におけるうつ状態に関連する因子の検討

  佐藤 晋爾; 村木 悦子; 石田 一希; 太田 深秀; 服部 功太郎; 内田 和彦; 功刀 浩; 朝田 隆  精神神経学雑誌  (2013特別)  S  -638  2013/05
• Blood biomarkers in depression

  功刀 浩; 藤井 さやか  精神科  22-  (3)  259  -267  2013/03
• CSF biomarkers for major depression

  服部 功太郎; 功刀 浩  医学のあゆみ  244-  (5)  502  -506  2013/02
• 精神神経疾患のバイオマーカーの探索と臨床応用に関する研究

  功刀 浩  精神・神経疾患研究開発費による研究報告集  203  -216  2013
• COGNITIVE FUNCTION IN MAJOR DEPRESSIVE DISORDER: THE ROLE OF SYMPTOMATOLOGY, PERSONALITY AND STRESS HORMONES

  H. Hori; J. Matsuo; T. Teraishi; S. Fujii; Y. Kawamoto; Y. Kinoshita; M. Ota; K. Hattori; T. Higuchi; H. Kunugi  EUROPEAN PSYCHIATRY  28-  2013
• 精神医学的障害の早期発見と早期介入:児童期から成人期への連続性・不連続性の解明研究

  神尾陽子; 高橋秀俊; 黒田美保; 金生由紀子; 功刀浩; 株田智弘; 坂田増弘; 小林庸子; 中鉢貴行; 川久保友紀; 石井礼花; 松田なつみ; 野中舞子; 濱田純子; 蔦森絵美; 森田健太郎; 松尾淳子; 山本宣子; 篠山大明; 堀弘明; 紺谷千穂; 畑中悠佑; 岡田知子; 飛松省三; 萩原綱一; 廣永成人; 六反一仁; 桑野由紀  精神・神経疾患研究開発費による研究報告集(2年度班・初年度班) 平成24年度  1-11,407  2013
• Possible mechanism underlying negative influence of glucocorticoids on BDNF-mediated neuronal function

  T. Numakawa; N. Adachi; S. Chiba; E. Kumamaru; Y. Ooshima; K. Hashido; H. Kunugi  JOURNAL OF NEUROCHEMISTRY  123-  122  -122  2012/10
• Behavioral phenotype observed in IL-1Ra KO after chronic mild immobilization stress

  C. Wakabayashi; T. Numakawa; Y. Kiyama; T. Manabe; H. Kunugi; Y. Iwakura  JOURNAL OF NEUROCHEMISTRY  123-  124  -124  2012/10
• Targeted molecule of brain-specific microRNA-132

  S. Kishi; T. Numakawa; H. Mizuno; N. Adachi; H. Kunugi; K. Hashido  JOURNAL OF NEUROCHEMISTRY  123-  118  -118  2012/10
• 安定同位体を用いた呼気ガス検査の精神疾患における有用性の検討

  寺石 俊也; 尾関 祐二; 堀 弘明; 篠山 大明; 千葉 秀一; 山本 宜子; 田中 治子; 飯嶋 良味; 松尾 淳子; 川本 由実子; 木下 裕紀子; 服部 功太郎; 太田 深秀; 梶原 正宏; 寺田 純雄; 樋口 輝彦; 功刀 浩  日本臨床精神神経薬理学会・日本神経精神薬理学会合同年会プログラム・抄録集  22回・42回-  201  -201  2012/10
• 被災地における軽度認知症と食事摂取量に関する予備的検討

  村木 悦子; 佐藤 晋爾; 石田 一希; 古賀 賀恵; 太田 深秀; 服部 功太郎; 朝田 隆; 功刀 浩  日本早期認知症学会プログラム・抄録集  13回-  115  -115  2012/09
• Association study of phencyclidine-responsive synapse-associated protein 97 (SAP97) gene in schizophrenia

  N. Yamamoto; A. Uezato; J. Sato-Kimura; E. Haramo; D. Jitoku; M. Umino; A. Umino; A. Kurumajii; Y. Iijima; H. Kunugi; T. Nishikawa  INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY  15-  140  -140  2012/06
• INTERLEUKIN-6 LEVELS IN CEREBROSPINAL FLUID OF PATIENTS WITH SCHIZOPHRENIA

  Daimei Sasayama; Kotaro Hattori; Haruko Tanaka; Hiroaki Hori; Toshiya Teraishi; Miho Ota; Naoji Amano; Hiroshi Kunugi  SCHIZOPHRENIA RESEARCH  136-  S230  -S230  2012/04
• SCHIZOTYPY AND GENETIC LOADING FOR SCHIZOPHRENIA IMPACT UPON NEUROPSYCHOLOGICAL STATUS IN BIPOLAR II AND UNIPOLAR MAJOR DEPRESSIVE DISORDERS

  Hiroaki Hori; Junko Matsuo; Toshiya Teraishi; Daimei Sasayama; Yumiko Kawamoto; Yukiko Kinoshita; Kotaro Hattori; Miyako Hashikura; Teruhiko Higuchi; Hiroshi Kunugi  SCHIZOPHRENIA RESEARCH  136-  S330  -S331  2012/04
• ANALYSES OF MONOAMINE METABOLITES IN THE CEREBROSPINAL FLUID OF PATIENTS WITH SCHIZOPHRENIA

  Kotaro Hattori; Daimei Sasayama; Toshiya Teraishi; Takashi Fujii; Hiroshi Kunugi  SCHIZOPHRENIA RESEARCH  136-  S137  -S137  2012/04
• Schizotypy and Genetic Loading for Schizophrenia Impact Upon Neuropsychological Status in Bipolar II and Unipolar Major Depressive Disorders

  Hiroaki Hori; Junko Matsuo; Toshiya Teraishi; Daimei Sasayama; Yumiko Kawamoto; Yukiko Kinoshita; Kotaro Hattori; Miyako Hashikura; Teruhiko Higuchi; Hiroshi Kunugi  BIOLOGICAL PSYCHIATRY  71-  (8)  88S  -88S  2012/04
• Dopamine agonists and depression

  功刀 浩  内分泌・糖尿病・代謝内科  34-  (2)  169  -175  2012/02
• 精神医学的障害の早期発見と早期介入:児童期から成人期への連続性・不連続性の解明研究

  神尾陽子; 高橋秀俊; 黒田美保; 金生由紀子; 功刀浩; 株田智弘; 稲田尚子; 中鉢貴行; 森脇愛子; 井口英子; 坂田増弘; 小林庸子; 川久保友紀; 菊池なつみ; 野中舞子; 石井礼花; 濱田順子; 蔦森絵美; 森田健太郎; 松尾淳子; 篠山大明; 堀弘明; 紺谷千穂; 畑中悠佑; 向野佳奈子; 和田圭司  精神・神経疾患研究開発費による研究報告集(2年度班・初年度班) 平成23年度  169  -183  2012
• 【脳の機能と統合失調症-新たな診断と治療への展望-II】脳脊髄液(CSF)からみた統合失調症のモノアミン代謝産物の解析

  服部 功太郎; 寺石 俊也; 篠山 大明; 功刀 浩  精神科治療学  26-  (12)  1557  -1563  2011/12
• RELA遺伝子は統合失調症のリスク及びプレパルス抑制の障害に関連する(RELA Gene is associated with risk for schizophrenia and deficits in prepulse inhibition)

  橋本 亮太; 大井 一高; 安田 由華; 福本 素由己; 山森 英長; 高橋 秀俊; 岩瀬 真生; 大河内 智; 数井 裕光; 斉藤 治; 巽 雅彦; 岩田 仲生; 尾崎 紀夫; 上島 国利; 功刀 浩; 武田 雅俊  日本臨床精神神経薬理学会・日本神経精神薬理学会合同年会プログラム・抄録集  21回・41回-  175  -175  2011/10
• 抗精神病薬を服用していない統合失調症患者におけるQT間隔の特徴

  尾関 祐二; 藤井 久彌子; 岡安 寛明; 大栗 有美子; 堀 弘明; 大類 方巳; 堀江 稔; 功刀 浩; 下田 和孝  日本臨床精神神経薬理学会・日本神経精神薬理学会合同年会プログラム・抄録集  21回・41回-  175  -175  2011/10
• ELEVATED CORTISOL LEVELS AND CORTISOL/DEHYDROEPIANDROSTERONE RATIO IN SCHIZOPHRENIA AS REVEALED BY THE DEXAMETHASONE SUPPRESSION TEST

  Hiroaki Hori; Toshiya Teraishi; Daimei Sasayama; Masanori Ishikawa; Teruhiko Higuchi; Hiroshi Kunugi  SCHIZOPHRENIA BULLETIN  37-  116  -116  2011/03
• ANALYSES OF FYN-TYROSINE KINASE AND N-METHYL-D-ASPARTATE (NMDA) RECEPTOR IN THE POST-MORTEM BRAINS OF SCHIZOPHRENIA

  Kotaro Hattori; H. Tanaka; C. Wakabayashi; H. Uchiyama; N. Yamamoto; Hiroaki Hori; T. Teraishi; K. Arima; H. Kunugi  SCHIZOPHRENIA BULLETIN  37-  190  -191  2011/03
• CROSS-CULTURAL COMPARISONS OF ATTITUDES TOWARD SCHIZOPHRENIA AMONGST THE GENERAL POPULATION AND PHYSICIANS: A SERIES OF WEB-BASED SURVEYS IN JAPAN AND THE UNITED STATES

  Misty Charissa Richards; Hiroaki Hori; H. Kunugi  SCHIZOPHRENIA BULLETIN  37-  279  -279  2011/03
• Schizophrenia and gene-environment interaction

  功刀 浩  Psychiatry  18-  (1)  19  -24  2011/01
• Association analysis of the Ser205Leu polymorphism of p75NTR with major depressive disorder

  Takashi Fujii; Noriko Yamamoto; Hiroaki Hori; Kotaro Hattori; Daimei Sasayama; Toshiya Teraishi; Miyako Hashikura; Masahiko Tatsumi; Nagahisa Okamoto; Teruhiko Higuchi; Hiroshi Kunugi  NEUROSCIENCE RESEARCH  71-  E304  -E304  2011
• Behavioral and molecular evidence for psychotropic effects in L-theanine

  Chisato Wakabayashi; Tadahiro Numakawa; Midori Ninomiya; Shuichi Chiba; Hiroshi Kunugi  NEUROSCIENCE RESEARCH  71-  E198  -E198  2011
• Interaction between miRNA-132 function and ERK signalings in BDNF-mediated synaptic function

  Soichiro Kishi; Tadahiro Numakawa; Naoki Adachi; Hideya Mizuno; Hiroshi Kunugi; Kazuo Hashido  NEUROSCIENCE RESEARCH  71-  E224  -E224  2011
• SLC1A1遺伝子多型と統合失調症との関連解析

  飯田周平; 堀内泰江; 飯嶋良味; 石黒浩毅; 稲田俊也; 渡部雄一郎; 染矢俊幸; 氏家寛; 岩田仲生; 尾崎紀夫; 功刀浩; 栃木衛; 糸川昌成; 新井誠; 新里和弘; 入谷修司; 柿田明美; 高橋均; 那波宏之; 有波忠雄  日本人類遺伝学会大会プログラム・抄録集  56th-  173  2011
• 心理臨床家のための脳科学講義(第9話)ドーパミンの威力と魔力

  功刀 浩  臨床心理学  10-  (6)  904  -910  2010/11
• PHENCYCLIDINE DECREASES EXCITATORY SYNAPSES: POSSIBLE INVOLVEMENT OF DYSFUNCTION OF BRAIN-DERIVED NEUROTROPHIC FACTOR

  N. Adachi; T. Numakawa; E. Kumamaru; C. Itami; Y. Iijima; M. Richards; R. Katoh-Semba; H. Kunugi  JOURNAL OF NEUROCHEMISTRY  115-  80  -80  2010/10
• うつ病対策の総合的提言

  武田 雅俊; 野村 総一郎; 神庭 重信; 久保 千春; 尾崎 紀夫; 笠井 清登; 加藤 忠史; 功刀 浩; 小山 司; 白川 治; 西田 淳志; 福田 正人; 元村 直靖; 山脇 成人  日本生物学的精神医学会誌 = Japanese journal of biological psychiatry  21-  (3)  155  -176  2010/09
• うつ病対策の総合的提言

  尾崎 紀夫; 笠井 清登; 加藤 忠史; 神庭 重信; 功刀 浩; 久保 千春; 小山 司; 白川 治; 西田 淳志; 野村 総一郎; 福田 正人; 元村 直靖; 山脇 成人; うつ病対策ワーキンググループ  日本生物学的精神医学会誌  21-  (3)  155  -176  2010/09
• 統合失調症患者を対象とした抗精神病薬とQT間隔との関連の検討

  尾関 祐二; 藤井 久彌子; 栗本 直樹; 山田 尚登; 大川 匡子; 青木 建亮; 高橋 淳; 石田 展弥; 堀江 稔; 功刀 浩  日本臨床精神神経薬理学会・日本神経精神薬理学会合同年会プログラム・抄録集  20回・40回-  101  -101  2010/09
• 抗うつ薬のQT間隔延長への影響の検討

  岡安 寛明; 尾関 祐二; 藤井 久彌子; 大栗 有美子; 佐伯 吉規; 堀 弘明; 樋口 輝彦; 功刀 浩; 下田 和孝  日本臨床精神神経薬理学会・日本神経精神薬理学会合同年会プログラム・抄録集  20回・40回-  196  -196  2010/09
• 統合失調症患者における血中サイトカイン濃度およびサイトカイン関連遺伝子のSNP解析(Analysis of plasma cytokine level and cytokine-related genetic polymorphism in schizophrenia)

  若林 千里; 篠山 大明; 功刀 浩  神経化学  49-  (2-3)  497  -497  2010/08
• 離乳後母ラットの不安様およびうつ様行動におけるERαと神経栄養因子の神経伝達の関与(Possible changes in neurotrophin signalings and levels of ER α are involved in anxiety- and depressive- like behaviors in postpartum rats after weaning)

  古田 都; 沼川 忠広; 二宮 碧; 千葉 秀一; 梶山 優; 柴田 重信; 舩橋 利也; 明間 立雄; 功刀 浩  神経化学  49-  (2-3)  652  -652  2010/08
• 心理臨床家のための脳科学講義(6)ドーパミンとその統合失調症における役割

  功刀 浩  臨床心理学  10-  (3)  429  -434  2010/05
• 統合失調症患者の運動機能障害に関するペグボードと握力検査による検討

  川本 由実子; 松尾 淳子; 橋倉 都; 木下 裕紀子; 須藤 志保; 堀 弘明; 寺石 俊也; 篠山 大明; 服部 功太郎; 尾関 祐二; 有馬 邦正; 石川 正憲; 岡本 長久; 樋口 輝彦; 功刀 浩  精神神経学雑誌  (2010特別)  S  -212  2010/05
• 統合失調症患者とうつ病患者の認知機能に関する日本語版統合失調症認知機能簡易評価尺度(BACS-J)による検討

  松尾 淳子; 木下 裕紀子; 川本 由実子; 須藤 志保; 橋倉 都; 堀 弘明; 寺石 俊也; 篠山 大明; 服部 功太郎; 尾関 祐二; 有馬 邦正; 石川 正憲; 岡本 長久; 樋口 輝彦; 兼田 康宏; 功刀 浩  精神神経学雑誌  (2010特別)  S  -213  2010/05
• ANALYSES OF FYN-TYROSINE KINASE IN SCHIZOPHRENIA

  Kotaro Hattori; Haruko Tanaka; Hirofumi Uchiyama; Noriko Yamamoto; Yoshimi Iljima; Takashi Fujii; Hiroaki Hori; Toshiya Teraishi; Masahiko Tatsumi; Mayu Omori; Nagahisa Okamoto; Yukiko Kinoshita; Junko Matsuo; Yumiko Kawamoto; Kunimasa Arima; Hiroshi Kunugi  SCHIZOPHRENIA RESEARCH  117-  (2-3)  256  -256  2010/04
• PLASMA LEVELS AND GENETIC POLYMORPHISMS OF INTERLEUKIN 6 AND INTERLEUKIN 10 IN SCHIZOPHRENIA

  Daimei Sasayama; Chisato Wakabayashi; Hirofumi Uchiyama; Yoshimi Iijima; Takashi Fujii; Hiroshi Kunugi  SCHIZOPHRENIA RESEARCH  117-  (2-3)  452  -453  2010/04
• ATTITUDES TOWARD SCHIZOPHRENIA IN THE GENERAL POPULATION, PSYCHIATRIC STAFF, PHYSICIANS, AND PSYCHIATRISTS: A WEB-BASED SURVEY IN JAPAN

  Hiroaki Hori; Misty Richards; Hiroshi Kunugi  SCHIZOPHRENIA RESEARCH  117-  (2-3)  401  -402  2010/04
• SCHIZOTYPAL PERSONALITY IN HEALTHY ADULTS IS RELATED TO BLUNTED HPA AXIS REACTIVITY

  Hiroaki Hori; Toshiya Teraishi; Yuji Ozeki; Junk Matsuo; Yumiko Kawamoto; Yukiko Kinoshita; Shiho Suto; Teruhiko Higuchi; Hiroshi Kunugi  SCHIZOPHRENIA RESEARCH  117-  (2-3)  375  -376  2010/04
• 大うつ病性障害とエンドフェノタイプとしてのHPA系の遺伝子解析 (特集 精神疾患の遺伝子は,本当にみつかったのか?)

  藤井 崇; 功刀 浩  分子精神医学  10-  (1)  33  -39  2010/01
• The roles of neurotrophic factors and stress in depression

  功刀 浩  Tottori journal of clinical research  3-  (1)  76  -82  2010
• A genetic association between schizophrenia and synapse-associated protein 97 (SAP97) gene

  A. Uezato; J. Kimura-Sato; N. Yamamoto; Y. Iijima; H. Kunugi; T. Nishikawa  INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY  13-  171  -171  2010
• Risk factors for QTc interval prolongation in real-world patients receiving antidepressants

  H. Okayasu; Y. Ozeki; K. Fujii; Y. Okuri; Y. Saeki; H. Kunugi; K. Shimoda; T. Higuchi; H. Hori  INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY  13-  80  -80  2010
• bFGF reversed a suppression in BDNF-stimulated glutamate release caused by glucocorticoid exposure

  Tadahiro Numakawa; Naoki Adachi; Emi Kumamaru; Hiroshi Kunugi  NEUROSCIENCE RESEARCH  68-  E141  -E141  2010
• Administration of NMDA receptor antagonist causes down-regulation of DISC1 expression and over migration of newly generated neurons in the adult hippocampus

  Takashi Namba; Kotaro Hattori; Hiroshi Kunugi; Kozo Kaibuchi; Shigeo Uchino; Shinichi Kohsaka  NEUROSCIENCE RESEARCH  68-  E367  -E367  2010
• Analysis of plasma cytokine level and cytokine-related genetic polymorphism in schizophrenia

  Chisato Wakabayashi; Daimei Sasayama; Hiroshi Kunugi  NEUROSCIENCE RESEARCH  68-  E84  -E84  2010
• Analyses of fyn-tyrosine-kinase in the genome and post-mortem brains of psychiatric disorders

  K. Hattori; H. Tanaka; H. Uchiyama; N. Yamamoto; Y. Iljima; H. Hori; T. Teraishi; Y. Kinoshita; J. Matsuo; K. Arima; H. Kunugi  INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY  13-  186  -186  2010
• Possible association of the semaphorin 3D gene (SEMA3D) with schizophrenia

  Takashi Fujii; Hirofumi Uchiyama; Noriko Yamamoto; Hiroaki Hori; Masahiko Tatsumi; Masanori Ishikawa; Kunimasa Arima; Teruhiko Higuchi; Hiroshi Kunugi  NEUROSCIENCE RESEARCH  68-  E313  -E313  2010
• Functional interactions between glucocorticoid and BDNF

  沼川 忠広; 功刀 浩  医学のあゆみ  231-  (10)  1015  -1018  2009/12
• 心理臨床家のための脳科学講義(3)統合失調症の脳形態異常--マクロとミクロから見えてくること

  功刀 浩  臨床心理学  9-  (6)  801  -807  2009/11
• ひと(File No. 03)Robin M. Murray

  功刀 浩  分子精神医学  9-  (4)  341  -343  2009/10
• Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse

  熊丸 絵美; 功刀 浩  Japanese journal of molecular psychiatry  9-  (4)  356  -358  2009/10
• 日本語版統合失調症認知機能簡易評価尺度(BACS-J)の有用性、妥当性に関する検討

  松尾 淳子; 木下 裕紀子; 須藤 志保; 橋倉 都; 堀 弘明; 寺石 俊也; 尾関 祐二; 有馬 邦正; 石川 正憲; 樋口 輝彦; 兼田 康宏; 功刀 浩  精神神経学雑誌  (2009特別)  S  -287  2009/05
• A beta-arrestin 2 signaling complex mediates lithium action on behavior

  千葉 秀一; 功刀 浩  Japanese journal of molecular psychiatry  9-  (2)  173  -176  2009/04
• 大うつ病の末梢白血球におけるPDE4B遺伝子の発現と関連研究

  沼田 周助; 中瀧 理仁; 伊賀 淳一; 田吉 伸哉; 谷口 京子; 住谷 さつき; 友竹 正人; 板倉 光夫; 亀ヶ谷 洋子; 巽 雅彦; 佐野 輝; 朝田 隆; 功刀 浩; 上野 修一; 大森 哲郎  精神薬療研究年報  (41)  29  -30  2009/03
• 代謝型グルタミン酸受容体遺伝子とうつ病の発症脆弱性・治療反応性との関連

  功刀 浩; 藤井 崇; 堀 弘明; 橋本 亮太; 朝田 隆; 巽 雅彦; 上島 国利; 樋口 輝彦  精神薬療研究年報  (41)  37  -38  2009/03
• 統合失調症脆弱性遺伝子ディスバインジンと記憶との関連:ヒトと動物モデルの表現型の検討

  橋本亮太; 橋本亮太; 橋本亮太; 高雄啓三; 高雄啓三; 服部聡子; 室谷知孝; 遠山桂子; 中西和男; 松崎伸介; 石塚智子; 石塚智子; 熊本奈都子; 高村明孝; 大井一高; 福本素由己; 山森英長; 山森英長; 安田由華; 安田由華; 遠山正彌; 遠山正彌; 大和谷厚; 大和谷厚; 功刀浩; 宮川剛; 宮川剛; 武田雅俊; 武田雅俊  日本生物学的精神医学会プログラム・講演抄録  31st-  2009
• 二段階サンプルによる関節リウマチ感受性遺伝子と統合失調症との関連研究

  金子尚史; 渡部雄一郎; 布川綾子; 村竹辰之; 有波忠雄; 氏家寛; 稲田俊也; 岩田仲生; 功刀浩; 糸川昌成; 音羽健司; 尾崎紀夫; 染矢俊幸  日本生物学的精神医学会プログラム・講演抄録  31st-  2009
• 染色体転座を持つ統合失調症患者の検討―PSAT1mRNA発現低下と血清L‐セリン及びグルタミン酸低下―

  尾関祐二; PICKARD Benjamin S; 藤井久彌子; MALLOY Mary P; 本多真; 白山幸彦; 涌井敬子; 福嶋義光; 功刀浩; MUIR Walter J; 伊豫雅臣; 橋本謙二; BLACKWOOD Douglas H; 澤明  日本生物学的精神医学会プログラム・講演抄録  31st-  120  2009
• 培養大脳皮質ニューロンにおいてシグマ1受容体アゴニストであるSA4503は生存維持効果を発揮する

  トルグン トルスン; 工藤 玄恵; 沼川 忠広; 安達 直樹; 熊丸 絵美; 功刀 浩  東京医科大学雑誌  66-  (4)  617  -617  2008/10
• Polymorphisms in the drug transporter gene ABCB1 predict antidepressant treatment response in depression

  藤井 崇; 功刀 浩  Japanese journal of molecular psychiatry  8-  (4)  364  -366  2008/10
• 精神神経疾患のリスク遺伝子 パニック障害の疾患感受性遺伝子に関するゲノムワイド関連研究(Risk genes for panic disorder: a GWAS study)

  谷井 久志; 佐々木 司; 音羽 健司; 加藤 忠史; 吉川 武男; 有波 忠雄; 功刀 浩; 染矢 俊幸; 松本 直道; 貝谷 久宣; 岡崎 祐士  神経化学  47-  (2-3)  217  -217  2008/08
• An association study of the human epsin 4 gene and schizophrenia in a Japanese population

  Y. Iijima; M. Richards; T. Shizun; H. Hori; M. Ohmori; K. Arima; O. Saitoh; H. Kunugi  INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY  11-  255  -256  2008/07
• Altered expression of BDNF gene and stress sensitization in schizophrenia

  H. Kunugi  INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY  11-  40  -41  2008/07
• 統合失調症脆弱性遺伝子ディスバインジンによる統合失調症の病態解明研究

  橋本 亮太; 服部 聡子; 室谷 知孝; 松崎 伸介; 石塚 智子; 熊本 奈都子; 大井 一高; 井池 直美; 安田 由華; 遠山 正彌; 大和谷 厚; 功刀 浩; 武田 雅俊  精神神経学雑誌  104th-  (2008特別)  S  -294  2008/05
• Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial

  泉 愛子; 功刀 浩  Japanese journal of molecular psychiatry  8-  (2)  142  -144  2008/04
• 視床下部-下垂体-副腎系とうつ病--最近の知見 (特集 気分障害研究の最前線)

  堀 弘明; 功刀 浩  分子精神医学  8-  (1)  17  -23  2008/01
• SA4503 a sigma receptor agonist, promotes the cell survival in cultured cortical neurons

  Tuerxun Tuerhong; Tadahirc Numakawa; Naoki Adachi; Emi Kumamaru; Matoshige Kudo; Hiroshi Kunugi  NEUROSCIENCE RESEARCH  61-  S94  -S94  2008
• Dysbindin and pathogenesis of schizophrenia

  Ryota Hashimoto; Satoko Hattori; Tomotaka Murotani; Shinsuke Matsuzaki; Keisuke Kawamoto; Kohei Yamada; Ryusuke Kuwahara; Tomoko Ishizuka; Natsuko Kumamoto; Masatoshi Takeda; Atsushi Yamatodani; Masaya Tohyama; Hiroshi Kunugi  NEUROSCIENCE RESEARCH  61-  S70  -S70  2008
• Behavioral alterations in prednisolone-treated mice

  Yu Kajiyama; Miyako Furuta; Midori Ninomiya; Shigenobu Shibata; Hiroshi Kunugi  NEUROSCIENCE RESEARCH  61-  S135  -S135  2008
• Glucocorticoid receptor promotes BDNF-stimulated intracellular signaling for glutamate release via interacting with TrkB

  Emi Kumamaru; Tadahiro Numakawa; Naoki Adachi; Yuki Yagasaki; Aiko Izumi; Hiroshi Kunugi  NEUROSCIENCE RESEARCH  61-  S48  -S48  2008
• Schizotypal traits and prefrontal activation patterns during a verbal fluency task: A near-infrared spectroscopy study

  Hiroaki Hori; Mitsue Nagamine; Takahiro Soshi; Shigeo Okabe; Sumio Terada; Yoshiharu Kim; Hiroshi Kunugi  NEUROSCIENCE RESEARCH  61-  S120  -S120  2008
• Glucocorticoid prevents BDNF-mediated synaptic maturation in developing hippocampal neurons

  Tadahiro Numakawa; Emi Kumamaru; Naoki Adachi; Hiroshi Kunugi  NEUROSCIENCE RESEARCH  61-  S36  -S36  2008
• Cyclophosphamide promotes the cell survival in cultured cortical neurons

  Hiromi Kitazawa; Tadahiro Numakawa; Emi Kumamaru; Naoki Adachi; Kunugi Hiroshi; Motoshige Kudo  NEUROSCIENCE RESEARCH  61-  S94  -S94  2008
• Chronic social defeat stress induces depression-like behavior and apoptosis in hippocampus

  Midori Ninomiya; Miyako Furuta; Yu Kajiyama; Shigenobu Shibata; Hiroshi Kunugi  NEUROSCIENCE RESEARCH  61-  S206  -S206  2008
• Intracellular increased BDNF expression is involved in synaptic dysfunction caused by phencyclidine in Cultured cortical neurons

  Naoki Adachi; Tadahiro Numakawa; Emi Kumamaru; Chiaki Itami; Ritsuko Senba; Hiroshi Kunugi  NEUROSCIENCE RESEARCH  61-  S128  -S128  2008
• Mineralocorticoid receptor overexpression in forebrain decreases anxiety-like behavior and alters the stress response in mice

  二宮 碧; 功刀 浩  Japanese journal of molecular psychiatry  7-  (4)  393  -395  2007/10
• 脳由来神経栄養因子遺伝子多型とストレス脆弱性

  功刀浩  精神神經學雜誌 = Psychiatria et neurologia Japonica  109-  (8)  771  -776  2007/08
• 遺伝子多型と臨床薬理 抗うつ薬の治療反応性を規定する遺伝子多型に関する薬力学的解析

  功刀 浩; 巽 雅彦; 橋本 亮太; 小菅 麻子; 上島 国利  臨床薬理の進歩  (28)  1  -7  2007/07
• 統合失調症脆弱性遺伝子ディスバインジンによる統合失調症の病態解明研究

  橋本 亮太; 安田 由華; 大井 一高; 井池 直美; 功刀 浩; 武田 雅俊  精神神経学雑誌  104th-  (2007特別)  S174  -S174  2007/05
• 【SNRIの現在】統合失調症に合併するうつ病

  尾関 祐二; 功刀 浩  精神科  10-  (5)  360  -364  2007/05
• Plasma levels of neurogenesis-related growth factors in patients with major depressive disorders

  M. Takebayashi; R. Hashimoto; K. Hisaoka; M. Tsuchioka; M. Ryoji; H. Kunugi  PSYCHIATRY AND CLINICAL NEUROSCIENCES  61-  (2)  S15  -S15  2007/04
• Association between schizophrenia and BDNF-linked complex polymorphic region (BDNF-LCPR)

  H. Kunugi; Y. Iijima; T. Okada; R. Hashimoto; T. Shizuno; H. Hori; T. Nakabayashi; T. Kato; T. Asada; M. Tatsumi; A. Kosuga; K. Kamijima; K. Arima; O. Saitoh  SCHIZOPHRENIA BULLETIN  33-  (2)  284  -284  2007/03
• Personality traits assessed with the temperament and character inventory in schizophrenia

  H. Hori; H. Noguchi; R. Hashimoto; T. Nakabayashi; O. Saitoh; R. M. Murray; S. Okabe; H. Kunugi  SCHIZOPHRENIA BULLETIN  33-  (2)  561  -562  2007/03
• 【統合失調症と感情障害の補助診断法の最近の進歩】統合失調症とうつ病におけるプレパルスインヒビションと関連指標 予備的報告

  功刀 浩; 柳沢 洋美; 田中 美穂; 岡本 洋平; 堀 弘明; 橋本 亮太; 中林 哲夫; 岡本 長久; 大森 まゆ; 沢村 香苗; 斎藤 治; 樋口 輝彦; 廣中 直行  精神医学  49-  (3)  253  -260  2007/03
• 向精神薬によるQTc延長リスクの遺伝学的評価

  尾関 祐二; 藤井 久彌子; 辻 啓子; 栗本 直樹; 大川 匡子; 功刀 浩; 堀江 稔  精神薬療研究年報  (39)  114  -117  2007/03
• 統合失調症脆弱性遺伝子であるディスバインジン欠損マウスにおける異常行動

  橋本亮太; 橋本亮太; 橋本亮太; 服部聡子; 室谷知孝; 松崎伸介; 松崎伸介; 石塚智子; 熊本奈津子; 武田雅俊; 武田雅俊; 遠山正彌; 遠山正彌; 大和谷厚; 大和谷厚; 功刀浩  日本生物学的精神医学会プログラム・講演抄録  29th-  2007
• Phencyclidine rapidly induced glutamate release and increased BDNF expression in cultured cortical neurons

  Naoki Adachi; Tadahiro Numakawa; Emi Kumamaru; Aiko Izumi; Hiroshi Kunugi  NEUROSCIENCE RESEARCH  58-  S122  -S122  2007
• Anxiolytic and antidepressant effects of estradiol in postpartum rats after weaning pup

  Miyako Furuta; Midori Ninomiya; Hiroshi Kunugi  NEUROSCIENCE RESEARCH  58-  S109  -S109  2007
• Glucocorticoid reduced the BDNF-mediated synaptic maturation in developing hippocampal neurons

  Emi Kumamaru; Tadahiro Numakawa; Naoki Adachi; Yuki Yagasaki; Aiko Izumi; Hiroshi Kunugi  NEUROSCIENCE RESEARCH  58-  S149  -S149  2007
• The combined DEX/CRH test as a marker of subjective stress in non-clinical population

  Hiroaki Hori; Shigeo Okabe; Hiroshi Kunugi  NEUROSCIENCE RESEARCH  58-  S165  -S165  2007
• Glucocorticoid and brain-derived neurotrophic factor in mood disorders

  Hiroshi Kunugi; Tadahiro Numakawa  NEUROSCIENCE RESEARCH  58-  S21  -S21  2007
• Survival effect of cyclophosphamide in cultured cortical neurons

  Hiromi Kitazawa; Tadahiro Numakawa; Naoki Adachi; Emi Kumamaru; Madinyet Niyaz; Aiko Izumi; Hiroshi Kunugi; Motoshige Kudo  NEUROSCIENCE RESEARCH  58-  S149  -S149  2007
• 細胞質のカルシウム反応に影響するミトコンドリアDNA12358多型と双極性障害の関連解析

  数野安亜; 宗像可枝; 南光進一郎; 功刀浩; 中村和彦; 森則夫; 山田和男; 吉川武男; 加藤進昌; 加藤忠史  日本生物学的精神医学会プログラム・講演抄録  29th-  227  2007
• うつ病の神経内分泌研究 (第5土曜特集 うつ病のすべて) -- (基礎的・生物学的研究)

  功刀 浩  医学のあゆみ  219-  (13)  1035  -1041  2006/12
• 【精神疾患研究の新たな戦略 病態解明・治療を目指して】精神疾患の遺伝と細胞モデル 統合失調症を中心に

  尾関 祐二; 功刀 浩  細胞工学  26-  (1)  17  -21  2006/12
• Serum levels of neurogenesis-related growth factor in patients with major depressive disorders

  竹林実; 橋本亮太; 橋本亮為; 久岡一恵; 土岡麻美; 龍治英; 功刀浩  神経化学  45-  (2/3)  493  -493  2006/08
• エンドフェノタイプを利用したゲノム研究 PACAP遺伝子と統合失調症の関連

  橋本 亮太; 功刀 浩; 馬場 明道  神経化学  45-  (2-3)  232  -232  2006/08
• 音性驚愕反応とそのプレパルスインヒビションは記憶機能・実行機能と関連する

  功刀 浩; 野口 広子; 岡本 洋平; 柳沢 洋子; 田中 美穂; 堀 弘明; 橋本 亮太; 廣中 直行  神経化学  45-  (2-3)  362  -362  2006/08
• 統合失調症における抗精神病薬治療と認知機能の関連

  堀 弘明; 野口 広子; 橋本 亮太; 中林 哲夫; 大森 まゆ; 高橋 晶; 津久江 亮太郎; 穴見 公隆; 平林 直次; 原田 誠一; 斎藤 治; 岩瀬 真生; 梶本 修身; 武田 雅俊; 岡部 繁男; 功刀 浩  神経化学  45-  (2-3)  377  -377  2006/08
• BDNF遺伝子のVal66Met多型は健常成人における年齢に関連した大脳白質微細構造の変化に影響する

  森 健之; 大西 隆; 根本 清貴; 守口 善也; 功刀 浩; 斉藤 治; 橋本 亮太; 松田 博史  神経化学  45-  (2-3)  395  -395  2006/08
• BDNF遺伝子における複合繰り返し配列多型と統合失調症との関連解析

  飯嶋 良味; 岡田 武也; 橋本 亮太; 志津野 朋子; 堀 弘明; 中林 哲夫; 加藤 忠史; 朝田 隆; 巽 雅彦; 小菅 麻子; 上島 国利; 原田 誠一; 有馬 邦正; 斉藤 治; 功刀 浩  神経化学  45-  (2-3)  474  -474  2006/08
• 統合失調症における脳形態の共分散性変化

  根本 清貴; 大西 隆; 森 健之; 守口 善也; 功刀 浩; 斉藤 治; 橋本 亮太; 朝田 隆  神経化学  45-  (2-3)  485  -485  2006/08
• Efficacy of atypical antipsychotic drugs for delusions in schizophrenia spectrum disorders

  Shinsuke Nakanishi; Toshihiko Takahashi; Hiroshi Kunugi  INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY  21-  (4)  A17  -A17  2006/07
• 統合失調症における知的機能の縦断的変化について 予備的検討

  野口 広子; 堀 弘明; 橋本 亮太; 中林 哲夫; 津久江 亮太郎; 穴見 公孝; 斉藤 治; 功刀 浩  Progress in Medicine  26-  (7)  1709  -1711  2006/07
• Susceptibility gene for schizophrenia : focus on dysbindin

  KUNUGI Hiroshi  脳と精神の医学 = Brain science and mental disorders  17-  (2)  105  -113  2006/06
• 統合失調症脆弱性遺伝子ディスバインジンによる統合失調症の分子病態研究

  橋本 亮太; 野口 広子; 堀 弘明; 功刀 浩  精神神経学雑誌  (2006特別)  S216  -S216  2006/05
• 統合失調症における情報処理障害の諸相 統合失調症における感覚運動ゲイティングの異常 プレパルス抑制テスト所見から

  功刀 浩; 橋本 亮太; 田中 美穂; 岡本 洋平; 堀 弘明; 中林 哲夫; 齋藤 治; 廣中 直行  精神神経学雑誌  (2006特別)  S305  -S305  2006/05
• 双極性障害患者におけるリチウム治療反応性とBCR遺伝子多型との関連

  増井 拓哉; 橋本 亮太; 久住 一郎; 鈴木 克治; 田中 輝明; 中川 伸; 鈴木 竜世; 岩田 仲生; 尾崎 紀夫; 加藤 忠史; 功刀 浩; 小山 司  精神神経学雑誌  (2006特別)  S372  -S372  2006/05
• 統合失調症と遺伝的リスクファクター (特集1 統合失調症解明へのアプローチ)

  功刀 浩  精神科  8-  (4)  269  -275  2006/04
• 統合失調症と遺伝環境相互作用 (特集 遺伝環境相互作用)

  功刀 浩  分子精神医学  6-  (2)  141  -148  2006/04
• 初代培養神経細胞においてCyclophosphamide Monohydrate（CP）は血清除去による細胞死を抑制する

  北澤 裕美; Madinyet Niyaz; 工藤 玄恵; 沼川 忠広; 功刀 浩  東京医科大学雑誌  64-  (1)  83  -83  2006/01
• Gene expression analysis of dysbindin mRNA in peripheral blood in schizophrenia

  Sachie Chiba; Satoko Hattori; Hiroaki Hori; Tetsuo Nakabayashi; Hiroshi Kunugi; Ryota Hashimoto  NEUROSCIENCE RESEARCH  55-  S232  -S232  2006
• Association of genetic variations of neurotrophins and their receptors with neuropsychiatric diseases

  Hiroshi Kunugi  NEUROSCIENCE RESEARCH  55-  S11  -S11  2006
• Chronic antidepressants potentiate via sigma-1 receptors the brain-derived neurotrophic factor-induced signaling for glutamate release

  Tadahiro Numakawa; Yuki Yagasaki; Emi Kumamaru; Teruo Hayashi; Su Tsung Ping; Hiroshi Kunugi  NEUROSCIENCE RESEARCH  55-  S115  -S115  2006
• Dysbindin knockout mouse reveals abnormal locomotor activity in novel environment

  Satoko Hattori; Sachie Chiba; Hiroshi Kunugi; Ryota Hashimoto  NEUROSCIENCE RESEARCH  55-  S232  -S232  2006
• Cyclophosphamide monohydrate (CP), an immunosuppression drug, protected cultured cortical neurons from cell death induced by serum deprivation

  Hiromi Kitazawa; Tadahiro Numakawa; Madiynet Niyaz; Emi Kumamaru; Yuki Yagasaki; Hiroshi Kunugi; Motoshige Kudo  NEUROSCIENCE RESEARCH  55-  S121  -S121  2006
• Genetic variation in dysbindin influences memory and general cognitive ability

  Ryota Hashimoto; Hiroko Noguchi; Hiroaki Hori; Tetsuo Nakabayashi; Satoko Hattori; Sachie Chiba; Seiichi Harada; Osamu Saito; Hiroshi Kunugi  NEUROSCIENCE RESEARCH  55-  S232  -S232  2006
• Inhibitory effect of glucocorticoid on BDNF-mediated maturation of synaptic function in developing hippocampal neurons

  Emi Kumamaru; Tadahiro Numakawa; Yuki Yagasaki; Hiroshi Kunugi  NEUROSCIENCE RESEARCH  55-  S89  -S89  2006
• MCI-186, a radical scavenger, protected cortical neurons from cell death through the activation of mitogen-activated protein kinase and phosphatidylinositol 3-kinase

  Madinyet Niyaz; Tadabiro Numakawa; Yoshinori Matsuki; Emi Kumamaru; Yuki Yagazaki; Harumi Kitazawa; Hiroshi Kunugi; Motoshige Kudo  NEUROSCIENCE RESEARCH  55-  S168  -S168  2006
• Effects of dexamethasone on emotional behavior and gene expression in mice

  Tomoko Soga; Yu Kajiyama; Shigenobu Shibata; Hiroshi Kunugi  NEUROSCIENCE RESEARCH  55-  S93  -S93  2006
• 精神科領域の用語解説 dysbindin(DTNBP1)

  橋本 亮太; 沼川 忠広; 矢ヶ崎 有希; 服部 聡子; 千葉 幸恵; 岡田 武也; 功刀 浩  分子精神医学  5-  (4)  444  -445  2005/10
• The gem interacting protein (GMIP) gene is associated with major depressive disorder

  K Tadokoro; R Hashimoto; M Tatsumi; A Kosuga; K Kamijima; H Kunugi  AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS  138B-  (1)  105  -105  2005/09
• The breakpoint cluster region (BCR) gene on chromosome 22q11 is associated with bipolar disorder

  R Hashimoto; T Okada; T Kato; A Kosuga; M Tatsumi; K Kamijima; H Kunugi  AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS  138B-  (1)  78  -78  2005/09
• Switching conventional antipsychotics to risperidone in stable patients with schizophrenia

  S Nakanishi; H Kunugi; T Takahashi  INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY  20-  (3)  A6  -A7  2005/05
• 統合失調症におけるCOMT(カテコールアミンメチルトランスフェラーゼ)Val/Met多型と前頭葉遂行機能(WCST)の検討

  橋本 亮太; 野口 広子; 志津野 朋子; 中林 哲夫; 堀 弘明; 馬場 敦; 工藤 耕太郎; 大森 まゆ; 高橋 晶; 津久江 亮大郎; 穴見 公隆; 平林 直次; 原田 誠一; 有馬 邦正; 斉藤 治; 功刀 浩  精神神経学雑誌  (2005特別)  S218  -S218  2005/05
• BDNF遺伝子の一塩基多型が脳構造に及ぼす影響

  根本 清貴; 橋本 亮太; 朝田 隆; 功刀 浩  精神神経学雑誌  (2005特別)  S225  -S225  2005/05
• BDNFのVal66Met多型とリチウムの治療反応性

  橋本 亮太; 増井 拓哉; 久住 一郎; 鈴木 克治; 田中 輝明; 中川 伸; 鈴木 竜世; 岩田 仲生; 尾崎 紀夫; 加藤 忠史; 小山 司; 功刀 浩  精神神経学雑誌  (2005特別)  S225  -S225  2005/05
• 双極性障害患者におけるリチウム治療反応性とXBP1遺伝子多型との関連

  増井 拓哉; 橋本 亮太; 久住 一郎; 鈴木 克治; 田中 輝明; 中川 伸; 功刀 浩; 小山 司  精神神経学雑誌  (2005特別)  S226  -S226  2005/05
• うつ病における内分泌学的エンドフェノタイプ:視床下部-下垂体-副腎系に焦点を当てて (特集 精神疾患のエンドフェノタイプ)

  功刀 浩  分子精神医学  5-  (2)  152  -158  2005/04
• Deficits in prepulse inhibition of acoustic startle are associated with positive symptoms in Japanese patients with schizophrenia

  H Kunugi; R Hashimoto; M Tanaka; H Hori; T Nakabayashi; O Saitoh; N Hironaka  SCHIZOPHRENIA BULLETIN  31-  (2)  457  -457  2005/04
• グルココルチコイドによる中枢神経細胞障害と神経栄養因子 抗うつ薬はグルココルチコイドと相反する作用をもつ

  矢ヶ崎 有希; 沼川 忠広; 熊丸 絵美; 橋本 亮太; 功刀 浩  精神薬療研究年報  (37)  205  -210  2005/03
• マウス海馬と前頭葉におけるDISC1およびdysbindin発現量に対する抗精神病薬の影響

  千葉幸恵; 千葉幸恵; 橋本亮太; 服部聡子; 養王田正文; 功刀浩  日本生物学的精神医学会プログラム・講演抄録  27th-  2005
• 過密飼育ストレスによる海馬の神経新生と行動への影響

  服部聡子; 橋本亮太; 沼川忠広; 矢ケ崎有希; 熊丸絵美; 功刀浩  日本生物学的精神医学会プログラム・講演抄録  27th-  2005
• 双極性障害におけるLIMの遺伝子発現および関連解析

  加藤忠史; 垣内千尋; 岩本和也; 茂野佳美; 山田和男; 三辺義雄; 中村和彦; 森則夫; 藤井久弥子; 南光進一郎; 功刀浩; 吉川武男  日本生物学的精神医学会プログラム・講演抄録  27th-  196  2005
• 【統合失調症 分子から治療まで】統合失調症の病態とディスバインジン

  橋本 亮太; 沼川 忠広; 矢ヶ崎 有希; 岡田 武也; 服部 聡子; 千葉 幸恵; 功刀 浩  脳21  8-  (1)  29  -33  2005/01
• 運動課題を用いた統合失調症患者の判別

  MIDORIKAWA AKIRA; HASHIMOTO RYOTA; NOGUCHI HIROKO; SAITO OSAMU; KUNUGI HIROSHI; NAKAMURA YOSHIKI  日本生物学的精神医学会プログラム・講演抄録  27th-  267  2005
• 統合失調症における認知機能障害の検討 統合失調症の包括的遺伝子解析研究に向けて

  野口 広子; 橋本 亮太; 中林 哲夫; 岩瀬 真生; 梶本 修身; 堀 弘明; 渡辺 剛; 武田 雅俊; 齊藤 治; 功刀 浩  精神神経学雑誌  106-  (11)  1428  -1428  2004/11
• 話題になった遺伝子多型のその後(8)tryptophan hydroxylase(TPH)遺伝子多型と精神疾患,自殺行動

  功刀 浩  分子精神医学  4-  (4)  328  -336  2004/10
• Association of HSPA5 with bipolar disorder in Japanese population

  C Kakiuchi; S Nanko; H Kunugi; T Kato  AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS  130B-  (1)  41  -41  2004/09
• Lack of support for a genetic association of the XBP1 promoter polymorphism with bipolar disorder in probands of European origin [1] (multiple letters)

  Sven Cichon; Silvia Buervenich; George Kirov; Nirmala Akula; Albena Dimitrova; Elaine Green; Johannes Schumacher; Norman Klopp; Tim Becker; Stephanie Ohlraun; Thomas G. Schulze; Monja Tullius; Magdalena M. Gross; Lisa Jones; Stefan Krastev; Ivan Nikolov; Marian Hamshere; Ian Jones; Piotr M. Czerski; Anna Leszczynska-Rodziewicz; Pawet Kapelski; Ann Van Den Bogaert; Thomas Illig; Joanna Hauser; Wolfgang Maier; Wade Berrettini; William Byerley; William Coryell; Elliot S. Gershon; John R. Kelsoe; Melvin G. McInnis; Dennis L. Murphy; John I. Nurnberger Jr.; Theodore Reich; William Scheftner; Michael C. O'Donovan; Peter Propping; Michael J. Owen; Marcella Rietschel; Markus M. Nöthen; Francis J. McMahon; Nick Craddock; Chihiro Kakiuchi; Shinichiro Nanko; Hiroshi Kunugi; Tadafumi Kato  Nature Genetics  36-  (8)  783  -785  2004/08
• 統合失調症脆弱性遺伝子ディスバインジンの関連解析と神経細胞における機能解析(Evidence of novel neuronal functions of dysbindin,a susceptibility gene for schizophrenia)

  橋本 亮太; 沼川 忠広; 矢ヶ崎 有希; 石本 哲也; 鈴木 竜世; 岩田 仲生; 尾崎 紀夫; 田口 隆久; 巽 雅彦; 上島 国利; Straub Richard; Weinberger Daniel; 功刀 浩  神経化学  43-  (2-3)  357  -357  2004/08
• モデル動物を用いた環境因子の気分障害(うつ病)に対する効果(Enriched environment influences depression-related behaviors and hippocampal neurogenesis)

  服部 聡子; 橋本 亮太; 宮川 剛; 前野 浩巳; 和田 圭司; 功刀 浩  神経化学  43-  (2-3)  501  -501  2004/08
• グルココルチコイドは培養大脳皮質ニューロンにおいてBDNFによるグルタミン酸放出を抑制する(Glucocorticoid suppresses brain-derived neurotrophic factor (BDNF) -regulated glutamatergic transmission in cultured cortical neurons)

  沼川 忠広; 矢ヶ崎 有希; 橋本 亮太; 功刀 浩  神経化学  43-  (2-3)  532  -532  2004/08
• 神経栄養因子遺伝子多型の気分障害における病因的役割と機能解析

  功刀 浩; 橋本 亮太; 田所 和幸; 岡田 武也; 吉田 満吏子; 巽 雅彦; 上島 国利  精神薬療研究年報  (36)  25  -30  2004/03
• Polymorphism screening of the neurotrophin receptor p75 gene and association analysis with schizophrenia

  H Kunugi; S Nanko  AMERICAN JOURNAL OF MEDICAL GENETICS  114-  (7)  855  -855  2002/10
• Possible effect of the APOE ε4 allele on the hippocampal volume and asymmetry in schizophrenia [1]

  T. Hata; H. Kunugi; S. Nanko; R. Fukuda; T. Kaminaga  American Journal of Medical Genetics - Neuropsychiatric Genetics  114-  (6)  641  -642  2002/08
• FLUVOXAMINEにより10年間の自閉生活を脱した社会恐怖の1症例 (第3回不安障害・気分障害研究会)

  繁田 真弓; 佐々木 直哉; 功刀 浩  分子精神医学  2-  (1)  92  -94  2002/01
• Brain MRI findings and relation with birthweight in schizophrenia

  T Hata; H Kunugi; R Fukuda; Tanaka, I; T Kaminaga; S Nanko  SCHIZOPHRENIA RESEARCH  53-  (3)  99  -99  2002/01
• Brain derived neurotrophic factor gene and schizophrenia: Polymorphism screening and association analysis

  H Kunugi; N Kato; S Nanko  SCHIZOPHRENIA RESEARCH  53-  (3)  71  -71  2002/01
• Association study of the G-protein beta3 subunit gene with schizophrenia and mood disorders

  H Kunugi; T Kato; R Fukuda; M Tatsumi; T Sakai; S Nanko  SCHIZOPHRENIA RESEARCH  53-  (3)  73  -73  2002/01
• Genes and structural abnormalities in schizophrenia

  T Hata; H Kunugi; R Fukuda; T Kaminaga; S Nanko  AMERICAN JOURNAL OF MEDICAL GENETICS  105-  (7)  603  -603  2001/10
• An association study between the BDNF gene and schizophrenia

  H Kunugi; S Nanko  AMERICAN JOURNAL OF MEDICAL GENETICS  105-  (7)  603  -604  2001/10
• The synaptic vesicle monoamine transporter (SVMT) gene and schizophrenia

  H Kunugi; S Ishida; A Akahane; S Nanko  AMERICAN JOURNAL OF MEDICAL GENETICS  105-  (7)  623  -623  2001/10
• 研究と報告 通電療法が著効したステロイド精神病の1例

  漆原 貴子; 功刀 浩; 池淵 恵美  精神医学  43-  (9)  987  -993  2001/09
• Molecular genetic study on structural brain abnormalities in schizophrenia

  T Hata; H Kunugi; R Fukuda; K Lee; A Akahane; T Kaminaga; S Nanko  SCHIZOPHRENIA RESEARCH  49-  (1-2)  156  -156  2001/04
• 精神分裂病の分子遺伝学研究 (特集 精神分裂病へのアプローチ--次世代への展望)

  功刀 浩  分子精神医学  1-  (1)  1  -11  2001/01
• 通電療法により慢性疼痛が改善したうつ病の1例

  漆原 貴子; 功刀 浩; 池淵 恵美; 内海 健; 広瀬 徹也  東京精神医学会誌  18-  (1)  27  -28  2000/12
• 精神分裂病の素因(遺伝)と生物学的機能 産科的合併症と周産期障害

  功刀 浩; 市来 真彦; 武井 教使; 大島 巌; 岡上 和雄; 馬場 元; 新井 平伊; 広瀬 徹也; 南光 進一郎  脳と精神の医学  11-  (3)  209  -217  2000/11
• Association study between reelin-related genes and schizophrenia.

  A Akahane; H Kunugi; M Harroti; H Tanaka; S Ishida; S Nanko  AMERICAN JOURNAL OF MEDICAL GENETICS  96-  (4)  535  -535  2000/08
• A case of schizophrenia with balanced translocation between chromosomes 6p and 17q.

  H Kunugi; N Sugawara; S Nanko  MOLECULAR PSYCHIATRY  4-  S36  -S37  1999/09
• Possible association of a dinucleotide repeat polymorphism in the neurotrophin-3 gene with hippocampal volume in schizophrenia.

  H Kunugi; T Kato; K Fujii; M Hattori; S Nanko  MOLECULAR PSYCHIATRY  4-  S36  -S36  1999/09
• Association analysis between a functional VNTR polymorphism in the promoter region of monoamine oxidase-A gene and mood disorders.

  S Ishida; H Kunugi; T Kato; M Tatsumi; T Sakai; M Hattori; T Hirose; S Nanko  MOLECULAR PSYCHIATRY  4-  S97  -S97  1999/09
• Novel polymorphisms in the promoter region of the neurotrophin-3 gene: Possible role in the pathogenesis of schizophrenia?.

  A Akahane; M Hattori; H Kunugi; R Morita; K Yamakawa; S Nanko  MOLECULAR PSYCHIATRY  4-  S30  -S30  1999/09
• Association between bipolar disorder and 5178/10398 polymorphisms in mitochondrial DNA.

  T Kato; H Kunugi; S Nanko; N Kato  MOLECULAR PSYCHIATRY  4-  S74  -S74  1999/09
• A case of a monozygotic twin pair discordant for schizophrenia a possible link between prenatal hypoxia and neurodevelopmental impairment

  H Kunugi; M Tsukue; RM Murray; S Nanko; T Hirose  SCHIZOPHRENIA RESEARCH  36-  (1-3)  91  -91  1999/04
• Intrauterine physical growth in schizophrenia: Evidence confirming excess of prematurity at birth

  M Ichiki; H Kunugi; N Takei; RM Murray; H Baba; H Arai; Ohshima, I; K Okagami; T Sato; T Hirose; S Nanko  SCHIZOPHRENIA RESEARCH  36-  (1-3)  43  -44  1999/04
• 胎生期からの発達に顕著な差が見られた一卵性双生児の精神分裂病不一致例

  津久江 美紀; 功刀 浩; 川手 恒太; 内海 健; 南光 進一郎; 広瀬 徹也  精神神経学雑誌  100-  (11)  998  -998  1998/11
• Chromosomal abnormalities in 254 schizophrenics.

  H Kunugi; KB Lee; S Nanko  AMERICAN JOURNAL OF MEDICAL GENETICS  81-  (6)  531  -531  1998/11
• Familial schizophrenia with pericentric inversion of chromosome 9: A case report.

  KB Lee; H Kunugi; S Nanko  AMERICAN JOURNAL OF MEDICAL GENETICS  81-  (6)  531  -531  1998/11
• Low-activity allele of catechol-O-methyltransferase gene associated with rapid-cycling bipolar disorder.

  G Kirov; KC Murphy; Jones, I; F McCandles; MJ Arranz; H Kunugi; RM Murray; DA Collier; P McGuffin; MJ Owen; N Craddock  AMERICAN JOURNAL OF MEDICAL GENETICS  74-  (6)  637  -638  1997/11
• Molecular genetics study of schizophrenia based on neurodevelopmental hypothesis.

  S Nanko; M Hattori; T Sasaki; H Kunugi  AMERICAN JOURNAL OF MEDICAL GENETICS  74-  (6)  564  -564  1997/11
• Small head circumference at birth in schizophrenia - Reply

  H Kunugi; S Nanko; K Saito; N Takei; RM Murray  SCHIZOPHRENIA RESEARCH  25-  (1)  83  -84  1997/05
• Maternal pre-eclampsia and schizophrenia: A case-control study with contemporaneously recorded obstetric data

  H Kunugi; S Nanko; N Takei; RM Murray; T Hirose  SCHIZOPHRENIA RESEARCH  24-  (1-2)  253  -253  1997/03
• 5HT(2a) receptor T102C polymorphism and schizophrenia

  T Sasaki; M Hattori; R Fukuda; H Kunugi; S Nanko  LANCET  347-  (9018)  1832  -1832  1996/06
• Serotonin transporter gene polymorphism and affective disorder

  H Kunugi; M Tatsumi; T Sakai; M Hattori; S Nanko  LANCET  347-  (9011)  1340  -1340  1996/05
• Increased obstetric complications in schizophrenia in a Japanese sample

  H Kunugi; S Nanko; N Takei; K Saito; S Akizuki; RM Murray  SCHIZOPHRENIA RESEARCH  18-  (2-3)  IIA6  -IIA6  1996/02
• A transmission disequilibrium study on catechol-O-methyltransferase polymorphism in schizophrenia families

  H Kunugi; HP Vallada; D Curtis; M Arranz; S Nanko; RM Murray; M Owen; P McGuffin; M Gill; DA Collier  SCHIZOPHRENIA RESEARCH  18-  (2-3)  IXB5  -IXB5  1996/02
• SMALL HEAD CIRCUMFERENCE AT BIRTH IN SCHIZOPHRENIA

  H KUNUGI; S NANKO; N TAKEI; K SAITO; RM MURRAY; H KAZAMATSURI  SCHIZOPHRENIA RESEARCH  15-  (1-2)  192  -193  1995/04
• MATERNAL LONG LABOR AND SCHIZOPHRENIA

  H KUNUGI; S NANKO; N TAKEI; K SAITO; RM MURRAY; H KAZAMATSURI  SCHIZOPHRENIA RESEARCH  15-  (1-2)  192  -192  1995/04
• THE INSTANTANEOUS RELATION BETWEEN ELECTROCARDIOGRAPHIC (ECG) MORPHOLOGY AND LEFT-VENTRICULAR STROKE VOLUME (SVLV) IN THE DOG

  MR PINSKY; H KUNIG  FASEB JOURNAL  2-  (6)  A1707  -A1707  1988/03

Research Grants & Projects

• Creation and clinical application of 3D brain barrier chips using human iPS cells

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B)

  Date (from‐to) : 2022/04 -2025/03 

  Author : 出口 芳春; 萩原 将也; 久保 義行; 功刀 浩; 川端 健二; 黒澤 俊樹
• [1-13C]Trpと[1-13C]5-HTPの合成とうつ病の客観的診断法の開発

  日本学術振興会：科学研究費助成事業 基盤研究(C)

  Date (from‐to) : 2021/04 -2024/03 

  Author : 梶原 康宏; 庄司 満; 功刀 浩
• Study of drug discovery and biomarker for depression based on glial antidepressant receptor (LPA1)

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B)

  Date (from‐to) : 2018/04 -2023/03 

  Author : 竹林 実; 功刀 浩; 井上 飛鳥
• Research on molecular and brain basis for sensorimotor gating dysfunction

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)

  Date (from‐to) : 2019/04 -2022/03 

  Author : Matsuo Junko
• A personality-based examination of the health-illness continuum: association with gene expression profiles

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)

  Date (from‐to) : 2016/07 -2019/03 

  Author : Hori Hiroaki; KUNUGI Hiroshi; YOSHIDA Fuyuko; NAKAMURA Seiji; KIM Yoshiharu; HIGUCHI Teruhiko
• Development of a novel biomarker and treatment for major depressive disorder focusing on the ethanolamine in the cerebrospinal fluid

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B)

  Date (from‐to) : 2016/04 -2018/03 

  Author : OGAWA Shintaro; KUNUGI Hiroshi; HATTORI Kotaro; OTA Miho; MATSUO Junko; CHIBA Shuichi
• Translational study on exercise program for promoting vitality of body and mind: unravel the mechanism of enhancing motivation and cognitive function in brain.

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (A)

  Date (from‐to) : 2015/04 -2018/03 

  Author : SOYA Hideaki
• Study on the serotonin kynurenine hypothesis by the stable isotope breath test in mood disorder

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)

  Date (from‐to) : 2015/04 -2018/03 

  Author : Teraishi Toshiya; KUNUGI Hiroshi; KAJIWARA Masahiro
• Study on the clinical use of (13)C-tryptophan breath test in depressive disorder

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research Grant-in-Aid for Challenging Exploratory Research

  Date (from‐to) : 2015/04 -2017/03 

  Author : Kunugi Hiroshi; TERAISHI Toshiya
• Quantitative analysis of lysophosphatidic acid (LPA) in serum and cerebrospinal fluid of depressed patients

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B)

  Date (from‐to) : 2015/04 -2017/03 

  Author : GOTOH LEO; YAMADA Mitsuhiko; SAITO Akiyoshi; YAMADA Misa; HATTORI Kotaro; KUNUGI Hiroshi
• Development of biomarkers for functional psychoses based on multiple omics analyses

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (A)

  Date (from‐to) : 2013/10 -2016/03 

  Author : Kunugi Hiroshi; HATTORI Kotaro; SASAYAMA Daimei
• うつ病の発症におけるＣＡＲＴの役割；人と動物を対象とした研究

  日本学術振興会：科学研究費助成事業 特別研究員奨励費

  Date (from‐to) : 2012 -2013 

  Author : 功刀 浩; YOON HyungShin
• The application of stable isotope breath test and biopterin administration to the evaluation and treatment of psychiatric disorders

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research Grant-in-Aid for Challenging Exploratory Research

  Date (from‐to) : 2010 -2011 

  Author : KUNUGI Hiroshi
• Role of neurotrophin receptor p75 in psychiatric diseases

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B)

  Date (from‐to) : 2008 -2011 

  Author : KUNUGI Hiroshi; NUMAKAWA Tadahiro; FUJII Takashi
• A Search for Risk Genes of Psychiatric Disorders

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research on Priority Areas

  Date (from‐to) : 2005 -2009 

  Author : OKAZAKI Yuji
• Search and functional analysis for candidate gene of schizophrenia by CGH array method.

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)

  Date (from‐to) : 2007 -2008 

  Author : OZEKI Yuji; KUNUGI Hiroshi
• Molecular genetic study on the pathophysiology of psychiatric disorders based on the role of PACAP

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B)

  Date (from‐to) : 2006 -2008 

  Author : SHINTANI Norihito; BABA Akemichi; AGO Yukio; HASHIMOTO Ryota; KUNUGI Hiroshi; TOHYAMA Masaya; TAKEDA Masatoshi
• プレパルス抑制検査を用いた統合失調症の病態の解明と診断法の開発

  日本学術振興会：科学研究費助成事業 萌芽研究

  Date (from‐to) : 2003 -2005 

  Author : 功刀 浩
• メチル化によるエピジェネティクなゲノム変化と統合失調症との関連解析

  日本学術振興会：科学研究費助成事業 萌芽研究

  Date (from‐to) : 2003 -2004 

  Author : 北條 浩彦; 功刀 浩
• Phylogenetic analyses of the HLA-DRB1 gene based on the DR haplotypes

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B)

  Date (from‐to) : 2002 -2003 

  Author : HOHJOH Hirohiko; TOKUNAGA Katsushi; ISHIDA Takafumi; KUNUGI Hiroshi
• Polymorphism screening and association analysis of neurotrophic factor genes in neuropsychiatric diseases

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 2001 -2002 

  Author : KUNUGI Hiroshi; NANKO Shinichiro
• Genome Scan of Candidate Region of Schizophrenia using DNA Pooling Method

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 1999 -2002 

  Author : NANKO Shinichiro; TOKUNAGA Katsushi
• 精神分裂病関連遺伝子の解明

  日本学術振興会：科学研究費助成事業

  Date (from‐to) : 2000 -2000 

  Author : 南光 進一郎; 功刀 浩
• Role of neurotrophic factors in the susceptibility to schizophrenia and its brain abnormalities

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 1999 -2000 

  Author : KUNUGI Hiroshi; SUZUKI Hidetoshi; NANKO Shinichiro
• Study of genetic markers on the short arm of the chromosome 6 (6p) in schizophrenia : analysis of schizophrenia susceptibility gene

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 1997 -1999 

  Author : SASAKI Tsukasa
• Relationships between polymorphisms of genes encoding neurotrophic factors and neurodevelopment in schizophrenia

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 1997 -1998 

  Author : KUNUGI Hiroshi; LEE Kyu-Bak; NANKO Shinichiro
• Molecular genetics study of schizophrenia based on neurodevelopmental hypothesis

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 1995 -1997 

  Author : NANKO Shinichiro; KUNUGI Hiroshi; HIROSE Tetsuya

Teaching Experience

PsychiatryPsychiatry Teikyo University

Media Coverage

• 将棋対局中の脳のエネルギー消費と栄養に関する取材

  Date : 2024/03/29

  Publisher, broadcasting station: 東海テレビ

  Program, newspaper magazine: ＮＥＷＳ ＯＮＥ

  Media report
• 勝負決める！？甘味の力 藤井聡太さん、王座戦での一品は－－ 速効で脳に栄養、心の安定 一方で弊害も

  Date : 2023/08/21

  Writer: Other than myself

  Publisher, broadcasting station: 毎日新聞 夕刊総合

  Program, newspaper magazine: 毎日新聞 夕刊総合

  カルチャー Paper
• 心の健康にも食事は大切！ メンタルヘルスと栄養の関係

  Date : 2023/07

  Writer: Other than myself

  Publisher, broadcasting station: サワイ健康推進課

  Program, newspaper magazine: 季節のテーマ

  https://kenko.sawai.co.jp/theme/202307.html Internet