Terada Kazuki

Researcher Information

Affiliation

Faculty of Pharmaceutical Sciences Senior Assistant Professor
Graduate School of Pharmaceutical Sciences Senior Assistant Professor

URL

https://jglobal.jst.go.jp/detail?JGLOBAL_ID=201601012494297681

Research funding number

• 00724197

J-Global ID

• 201601012494297681

Research Interests

• 神経薬理   シグマ受容体   神経成長因子   うつ病   神経変性疾患   

Research Areas

• Life sciences / Pharmacology / 神経薬理学

Academic & Professional Experience

• 2021/04 - 2024/03  Himeji Dokkyo UniversityFaculty of Pharmaceutical Sciences
• 2016/04 - 2021/03  Fukuoka UniversityFaculty of Pharmaceutical Sciences

Association Memberships

• THE PHARMACEUTICAL SOCIETY OF JAPAN   European College of Neuropsychopharmacology   日本神経精神薬理学会   日本薬理学会   

Research Activity Information

Published Papers

• Pseudogenization of the Slc23a4 gene is necessary for the survival of Xdh-deficient mice.

  Kazuki Terada; Tamaki Watanabe; Nobuhiro Yasuno; Toshio Ohtsubo; Shigeru Shibata; Kimiyoshi Ichida; Makoto Hosoyamada

  Scientific reports 15 (1) 3250 - 3250 2025/01
• Divergent effects of chronic continuous and intermittent social defeat stress on emotional behaviors: Impact on phosphorylated CREB and BDNF protein levels in the rat hippocampus.

  Hiroyoshi Harada; Masayoshi Mori; Yusuke Murata; Yuri Kohno; Kazuki Terada; Kenji Ohe; Munechika Enjoji

  Neuroscience letters 835 137851 - 137851 2024/07
• Rectification of ATP-gated current of rat P2X2 and P2X7 receptors depends on the cytoplasmic N-terminus.

  Keisuke Migita; Kohei Oyabu; Kazuki Terada

  Biochemical and biophysical research communications 688 149213 - 149213 2023/12
• Bortezomib Increased Vascular Permeability by Decreasing Cell-Cell Junction Molecules in Human Pulmonary Microvascular Endothelial Cells.

  Taichi Matsumoto; Junichi Matsumoto; Yuka Matsushita; Moeno Arimura; Kentaro Aono; Mikiko Aoki; Kazuki Terada; Masayoshi Mori; Yutaka Haramaki; Takuya Imatoh; Atsushi Yamauchi; Keisuke Migita

  International journal of molecular sciences 24 (13) 2023/06
• Dynamic Changes of Behavioral Despair, HPA Axis Activity, and Hippocampal Neurogenesis in Male Rats Induced by Social Defeat Stress.

  Hiroyoshi Harada; Masayoshi Mori; Yusuke Murata; Shunsuke Kawanabe; Kazuki Terada; Taichi Matsumoto; Kenji Ohe; Munechika Enjoji

  Journal of integrative neuroscience 22 (2) 43 - 43 2023/02 [Refereed]
  
• Delivery of the reduced form of vitamin K2(20) to NIH/3T3 cells partially protects against rotenone induced cell death

  Erina Toki; Shotaro Goto; Shuichi Setoguchi; Kazuki Terada; Daisuke Watase; Hirofumi Yamakawa; Ayano Yamada; Mitsuhisa Koga; Kaori Kubota; Katsunori Iwasaki; Yoshiharu Karube; Kazuhisa Matsunaga; Jiro Takata

  Scientific Reports Springer Science and Business Media LLC 12 (1) 2022/11 [Refereed]
  
• Oxytocin treatment improves dexamethasone-induced depression-like symptoms associated with enhancement of hippocampal CREB-BDNF signaling in female mice.

  Masayoshi Mori; Hiromi Shizunaga; Hiroyoshi Harada; Yuki Tajiri; Yusuke Murata; Kazuki Terada; Kenji Ohe; Munechika Enjoji

  Neuropsychopharmacology reports 42 (3) 356 - 361 2022/09 [Refereed]
  
• Growth Inhibitory Effects of Ester Derivatives of Menahydroquinone-4, the Reduced Form of Vitamin K2(20), on All-Trans Retinoic Acid-Resistant HL60 Cell Line.

  Hirofumi Yamakawa; Shuichi Setoguchi; Shotaro Goto; Daisuke Watase; Kazuki Terada; Nami Nagata-Akaho; Erina Toki; Mitsuhisa Koga; Kazuhisa Matsunaga; Yoshiharu Karube; Jiro Takata

  Pharmaceutics 13 (5) 2021/05 [Refereed]
  
• Bortezomib enhances G-CSF-induced hematopoietic stem cell mobilization by decreasing CXCL12 levels and increasing vascular permeability.

  Taichi Matsumoto; Yasushi Takamatsu; Hanae Moriyama; Kazuki Terada; Masayoshi Mori; Kazuhiko Ono; Keisuke Migita; Shuuji Hara

  Experimental hematology 97 21 - 31 2021/05 [Refereed]
  
• Ziprasidone protects against rotenone-induced oxidative stress in PC12 neuronal cells

  E. Toki; A. Murata; K. Terada; N. Nishihara; S. Goto; H. Yamakawa; K. Matsunaga; Y. Karube

  European Neuropsychopharmacology Elsevier BV 40 S204 - S204 0924-977X 2020/11 [Refereed]
  
• Evaluation of photostability and phototoxicity of esterified derivatives of ubiquinol-10 and their application as prodrugs of reduced coenzyme Q10 for topical administration.

  Shuichi Setoguchi; Nami Nagata-Akaho; Shotaro Goto; Hirofumi Yamakawa; Daisuke Watase; Kazuki Terada; Mitsuhisa Koga; Kazuhisa Matsunaga; Yoshiharu Karube; Jiro Takata

  BioFactors 46 (6) 983 - 994 2020/10 [Refereed]
  
• Atypical Antipsychotic Drug Ziprasidone Protects against Rotenone-Induced Neurotoxicity: An In Vitro Study.

  Kazuki Terada; Ayumi Murata; Erina Toki; Shotaro Goto; Hirofumi Yamakawa; Shuichi Setoguchi; Daisuke Watase; Mitsuhisa Koga; Jiro Takata; Kazuhisa Matsunaga; Yoshiharu Karube

  Molecules 25 (18) 2020/09 [Refereed]
  
• Ester derivatives of phyllohydroquinone effectively deliver the active form of vitamin K1 topically, owing to their non-photosensitivity.

  Shotaro Goto; Shuichi Setoguchi; Nami Nagata-Akaho; Kazuki Terada; Daisuke Watase; Hirofumi Yamakawa; Erina Toki; Mitsuhisa Koga; Kazuhisa Matsunaga; Yoshiharu Karube; Jiro Takata

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 155 105519 - 105519 2020/08 [Refereed]
  
• Continuous psychosocial stress stimulates BMP signaling in dorsal hippocampus concomitant with anxiety-like behavior associated with differential modulation of cell proliferation and neurogenesis.

  Masayoshi Mori; Yusuke Murata; Mariko Tsuchihashi; Naoko Hanakita; Fumie Terasaki; Hiroyoshi Harada; Shunsuke Kawanabe; Kazuki Terada; Taichi Matsumoto; Kenji Ohe; Kazunori Mine; Munechika Enjoji

  Behavioural brain research 392 112711 - 112711 2020/08 [Refereed]
  
• Fluvoxamine recovered the nerve growth factor-induced neurite outgrowth inhibited by dexamethasone

  E. Toki; K. Terada; S. Goto; H. Yamakawa; K. Matsunaga; D. Watase; S. Setoguchi; J. Takata; Y. Karube

  European Neuropsychopharmacology Elsevier BV 29 S219 - S219 0924-977X 2019/12 [Refereed]
  
• Sigma-2 receptor as a potential therapeutic target for treating central nervous system disorders.

  Terada K; Migita K; Matsushima Y; Kamei C

  Neural regeneration research Medknow 14 (11) 1893 - 1894 1673-5374 2019/11 [Refereed]
  
• FF-10501 induces caspase-8-mediated apoptotic and endoplasmic reticulum stress-mediated necrotic cell death in hematological malignant cells.

  Matsumoto T; Jimi S; Migita K; Terada K; Mori M; Takamatsu Y; Suzumiya J; Hara S

  International journal of hematology 110 (5) 606 - 617 0925-5710 2019/11 [Refereed]
  
• Effects of geldanamycin on neurite outgrowth-related proteins and kinases in nerve growth factor-differentiated pheochromocytoma 12 cells.

  Migita K; Matsumoto T; Terada K; Ono K; Hara S

  Journal of pharmacological sciences 140 (3) 255 - 262 1347-8613 2019/07 [Refereed]
  
• Muscarinic M₁ receptors stimulated by intracerebroventricular administration of McN-A-343 reduces the nerve injury-induced mechanical hypersensitivity via GABA_B receptors rather than GABA_A receptors in mice.

  Migita K; Nishimura A; Eto F; Koga K; Matsumoto T; Terada K; Hara S; Honda K

  Journal of pharmacological sciences 1347-8613 2019/06 [Refereed]
  
• Sertraline inhibits nerve growth factor-induced neurite outgrowth in PC12 cells via a mechanism involving the sigma-1 receptor.

  Matsushima Y; Terada K; Kamei C; Sugimoto Y

  European journal of pharmacology Elsevier BV 853 129 - 135 0014-2999 2019/06 [Refereed]
  
• Prodrugs for Skin Delivery of Menahydroquinone-4, an Active Form of Vitamin K2(20), Could Overcome the Photoinstability and Phototoxicity of Vitamin K2(20).

  Shotaro Goto; Shuichi Setoguchi; Hirofumi Yamakawa; Daisuke Watase; Kazuki Terada; Kazuhisa Matsunaga; Yoshiharu Karube; Jiro Takata

  International journal of molecular sciences 20 (10) 2019/05 [Refereed]
  
• Effects of fluvoxamine on nerve growth factor-induced neurite outgrowth inhibition by dexamethasone in PC12 cells.

  Matsushima Y; Terada K; Takata J; Karube Y; Kamei C; Sugimoto Y

  Bioscience, biotechnology, and biochemistry Informa UK Limited 83 (4) 659 - 665 0916-8451 2019/04 [Refereed]
  
• Stimulating muscarinic M1 receptors in the anterior cingulate cortex reduces mechanical hypersensitivity via GABAergic transmission in nerve injury rats

  KOGA Kohei; MATSUZAKI Yu; MIGITA Keisuke; SHIMOYAMA Shuji; ETO Fumihiro; NAKAGAWA Tatsuki; MATSUMOTO Taichi; TERADA Kazuki; MISHIMA Ken-Ichi; FURUE Hidemasa; HONDA Kenji

  Brain Research ELSEVIER 1704 187 - 195 0006-8993 2019/02 [Refereed]
  
• The Kampo medicine Yokukansan (YKS) enhances nerve growth factor (NGF)-induced neurite outgrowth in PC12 cells.

  Terada K; Matsushima Y; Matsunaga K; Takata J; Karube Y; Ishige A; Chiba K

  Bosnian journal of basic medical sciences Association of Basic Medical Sciences of FBIH 18 (3) 224 - 233 1512-8601 2018/08 [Refereed]
  
• Antitumor Effects and Delivery Profiles of Menahydroquinone-4 Prodrugs with Ionic or Nonionic Promoiety to Hepatocellular Carcinoma Cells.

  Setoguchi S; Watase D; Matsunaga K; Yamakawa H; Goto S; Terada K; Ohe K; Enjoji M; Karube Y; Takata J

  Molecules (Basel, Switzerland) MDPI AG 23 (7) 1738 - 1738 2018/07 [Refereed]
  
• Cholinesterase inhibitor rivastigmine enhances nerve growth factor-induced neurite outgrowth in PC12 cells via sigma-1 and sigma-2 receptors.

  Terada K; Migita K; Matsushima Y; Sugimoto Y; Kamei C; Matsumoto T; Mori M; Matsunaga K; Takata J; Karube Y

  PloS one Public Library of Science (PLoS) 13 (12) e0209250 - e0209250 2018 [Refereed]
  
• Estimation of Interindividual Variability of Pharmacokinetics of CYP2C9 Substrates in Humans.

  Chiba K; Shimizu K; Kato M; Miyazaki T; Nishibayashi T; Terada K; Sugiyama Y

  Journal of pharmaceutical sciences 106 (9) 2695 - 2703 0022-3549 2017/09 [Refereed]
  
• Relationship between the acyl chain length of paradol analogues and their antiobesity activity following oral ingestion.

  Haratake A; Watase D; Setoguchi S; Terada K; Matsunaga K; Takata J

  Journal of agricultural and food chemistry 62 (26) 6166 - 6174 0021-8561 2014/07 [Refereed]
  
• Fluvoxamine moderates reduced voluntary activity following chronic dexamethasone infusion in mice via recovery of BDNF signal cascades.

  Terada K; Izumo N; Suzuki B; Karube Y; Morikawa T; Ishibashi Y; Kameyama T; Chiba K; Sasaki N; Iwata K; Matsuzaki H; Manabe T

  Neurochemistry international 69 9 - 13 0197-0186 2014/04 [Refereed]
  
• Inhibition of nerve growth factor-induced neurite outgrowth from PC12 cells by dexamethasone: signaling pathways through the glucocorticoid receptor and phosphorylated Akt and ERK1/2.

  Terada K; Kojima Y; Watanabe T; Izumo N; Chiba K; Karube Y

  PloS one 9 (3) e93223  2014 [Refereed]
  
• Prediction of inter-individual variability in the pharmacokinetics of CYP2C19 substrates in humans.

  Chiba K; Shimizu K; Kato M; Nishibayashi T; Terada K; Izumo N; Sugiyama Y

  Drug metabolism and pharmacokinetics 29 (5) 379 - 386 1347-4367 2014 [Refereed]
  
• Lactoferrin enhances mineralization on osteoblast like MC3T3-E1 cell

  Izumo N; Kikuchi S; Ishibashi Y; Terada K; Chiba K; Hidefumi H; Kagaya S; Hoshino T

  Lactoferrin 29 - 34 2013/03 [Refereed]
  

Books etc

• 薬学生のための病態検査学

  三浦, 雅一 南江堂 2023/12 9784524404278 xxviii, 289p
• 放射線・放射性物質の薬学利用

  加留部善晴; 後藤将太朗; 瀬戸口修一; 髙田二郎; 寺田一樹; 松永和久; 山川博文; 渡瀬大輔 (Joint work)2018/02

Research Grants & Projects

• シグマ-2受容体を標的とした神経新生に基づく新規うつ病治療薬の構築

  日本学術振興会：科学研究費助成事業 基盤研究(C)

  Date (from‐to) : 2022/04 -2026/03 

  Author : 寺田 一樹; 森 征慶; 松本 太一
• 血管透過性亢進に起因するボルテゾミブ誘発性肺障害の発症機序解明

  日本学術振興会：科学研究費助成事業: 基盤研究(C)

  Date (from‐to) : 2021/04 -2024/03 

  Author : 松本太一; 寺田一樹
• BCRP輸送体の新規発現調節機構に基づく薬物動態の最適化

  公益財団法人 中富健康科学新興財団：研究助成金

  Date (from‐to) : 2021/04 -2022/03 

  Author : 寺田一樹
• 子宮頸がんの放射線治療に対する耐性形成の検証と克服戦略

  公益財団法人 放射線影響協会：研究奨励助成金

  Date (from‐to) : 2020/04 -2021/03 

  Author : 寺田一樹
• ステロイド誘起性うつ病における病態実験モデル構築と治療薬の提案

  日本学術振興会: 科学研究費助成事業: 若手研究B：

  Date (from‐to) : 2016/04 -2020/03 

  Author : 寺田 一樹

Teaching Experience

Clinical biochemistryClinical biochemistry Himeji Dokkyo University
PharmacotherapyPharmacotherapy Himeji Dokkyo University