Sakuda Shohei

Researcher Information

Affiliation

Department of Integrated Science and Engineering,Environment and Biotechnology Course Specially Appointed Professor
Graduate School of Science and Engineering Specially Appointed Professor
Division of Integrated Science and Engineering Specially Appointed Professor
Graduate School of Science and Engineering Dean

Degree

• (BLANK)（The University of Tokyo）

URL

https://jglobal.jst.go.jp/detail?JGLOBAL_ID=200901011269333910

J-Global ID

• 200901011269333910

Profile

• 1982年 東京大学農学部卒
  1986年 東京大学大学院博士課程中退、同年大阪大学工学部助手
  1994年 東京大学農学部助教授
  2018年 帝京大学理工学部教授・研究科長
  2016年～ 日本マイコトキシン学会長　2022年～日本キチンキトサン学会長
  専門分野：生物有機化学
  研究テーマ：微生物、植物などの生理活性物質

Research Interests

• 生合成   生物活性物質   キチナーゼ   マイコトキシン   二次代謝産物   biosynthesis   bioactive compounds   chitinase   mycotoxin   secondary metabolite   

Research Areas

• Life sciences / Bioorganic chemistry

Academic & Professional Experience

• 2018/04 - Today  Teikyo UniversityFaculty of Science and Engineering
• 1994/11 - 2018/03  The University of TokyoGraduate School of Agricultural and Life Sciences
• 1986 - 1994  Osaka UniversitySchool of Engineering

Education

•        - 1986  The University of Tokyo
•        - 1982  The University of Tokyo

Association Memberships

• 日本キチン・キトサン学会   日本放線菌学会   日本マイコトキシン学会   日本農芸化学会   

Research Activity Information

Published Papers

• Inhibition of Aflatoxin Production in Aspergillus flavus by a Klebsiella sp. and Its Metabolite Cyclo(l-Ala-Gly)

  Shohei Sakuda; Masaki Sunaoka; Maho Terada; Ayaka Sakoda; Natsumi Ishijima; Noriko Hakoshima; Kenichi Uchida; Hirofumi Enomoto; Tomohiro Furukawa

  Toxins MDPI AG 16 (3) 141 - 141 2024/03 [Refereed]
  
• The Mechanism of Ochratoxin Contamination of Artificially Inoculated Licorice Roots.

  Abdelrahman Elamin; Hirofumi Enomoto; Maiko Watanabe; Shohei Sakuda

  Toxins 15 (3) 2023/03 [Refereed]
  
• Structural and functional analyses of chitinolytic enzymes in the nacreous layer of Pinctada fucata

  Lingxiao Zhu; Keisuke Shimizu; Hiroyuki Kintsu; Lumi Negishi; Zehua Zheng; Hitoshi Kurumizaka; Shohei Sakuda; Isao Kuriyama; Takashi Atsumi; Kaoru Maeyama; Kiyohito Nagai; Michiyo Kawabata; Hisanori Kohtsuka; Toru Miura; Yoshitaka Oka; Shinsuke Ifuku; Koji Nagata; Michio Suzuki

  BIOCHEMICAL ENGINEERING JOURNAL 191 1369-703X 2023/02 [Refereed]
  
• Low-dose ethanol increases aflatoxin production due to the adh1-dependent incorporation of ethanol into aflatoxin biosynthesis

  Tomohiro Furukawa; Masayo Kushiro; Hiroyuki Nakagawa; Hirofumi Enomoto; Shohei Sakuda

  iScience Elsevier BV 106051 - 106051 2589-0042 2023/01 [Refereed]
  
• Plant Chitinase Mutants as the Catalysts for Chitooligosaccharide Synthesis Using the Sugar Oxazoline Derivatives.

  Naoyuki Umemoto; Natsuki Saito; Masato Noguchi; Shin-Ichiro Shoda; Takayuki Ohnuma; Takeshi Watanabe; Shohei Sakuda; Tamo Fukamizo

  Journal of agricultural and food chemistry 70 (40) 12897 - 12906 2022/10 [Refereed]
  
• A new metabolite, mannogeranylnerol, specifically produced at body temperature by Schizophyllum commune, a causative fungus of human mycosis.

  Shing Yiu Tam; Kenichi Uchida; Hirofumi Enomoto; Senji Takahashi; Koichi Makimura; Shohei Sakuda

  The Journal of antibiotics 75 (4) 243 - 246 2022/04 [Refereed]
  
• Low-Dose Ethanol Increases Aflatoxin Production in <i>Aspergillus Flavus</i> Due to the <i>Adh1</i>-Dependent Incorporation of Ethanol Into Aflatoxin Biosynthesis

  Tomohiro Furukawa; Masayo Kushiro; Hiroyuki Nakagawa; Shohei Sakuda

  SSRN Electronic Journal Elsevier BV 2022 [Refereed]
  
• β-1,3-Glucanases and chitinases participate in the stress-related defence mechanisms that are possibly connected with modulation of arabinogalactan proteins (AGP) required for the androgenesis initiation in rye (Secale cereale L.)

  Kamil Zieliński; Ewa Dubas; Zuzana Gerši; Monika Krzewska; Agnieszka Janas; Anna Nowicka; Ildikó Matušíková; Iwona Żur; Shohei Sakuda; Jana Moravčiková

  Plant Science Elsevier BV 110700 - 110700 0168-9452 2020/10 [Refereed]
  
• Inhibition of aflatoxin production by protein tyrosine phosphatase inhibitors, blasticidin A and dephostatin

  井之口曜; 井之口曜; 古川智宏; 古川智宏; 吉成知也; 作田庄平; 作田庄平

  JSM Mycotoxins 69 (2) 71 - 79 0285-1466 2020/07 [Refereed]
  
• Dioctatin Activates ClpP to Degrade Mitochondrial Components and Inhibits Aflatoxin Production

  Tomohiro Furukawa; Hidekazu Katayama; Akira Oikawa; Lumi Negishi; Takuma Ichikawa; Michio Suzuki; Kohji Murase; Seiji Takayama; Shohei Sakuda

  Cell Chemical Biology 27 (11) 1396 - 1409.e10 2451-9456 2020 [Refereed]
  
• Structural and Thermodynamic Signatures of Ligand Binding to the Enigmatic Chitinase D of Serratia proteamaculans

  Jogi Madhuprakash; Bjørn Dalhus; Gustav Vaaje-Kolstad; Shohei Sakuda; Appa Rao Podile; Vincent G.H. Eijsink; Morten Sørlie

  Journal of Physical Chemistry B 123 (10) 2270 - 2279 1520-6106 2019/03 [Refereed]
  
• Inhibition of aflatoxin production by paraquat and external superoxide dismutase in aspergillus flavus

  Tomohiro Furukawa; Shohei Sakuda

  Toxins 11 (2) 2072-6651 2019/02 [Refereed]
  
• Structural and functional analyses of calcium ion response factors in the mantle of Pinctada fucata

  Akihiro Matsuura; Ko Yoshimura; Hiroyuki Kintsu; Takashi Atsumi; Yasushi Tsuchihashi; Takeshi Takeuchi; Noriyuki Satoh; Lumi Negishi; Shohei Sakuda; Tomiko Asakura; Yuki Imura; Etsuro Yoshimura; Michio Suzuki

  Journal of Structural Biology 204 (2) 240 - 249 1047-8477 2018/11 [Refereed]
  
• Exploring an Artificial Metabolic Route in Fusarium sporotrichioides: Production and Characterization of 7-Hydroxy T-2 Toxin

  Kentaro Kamata; Hiroki Sato; Kazuyuki Maeda; Kazuo Furihata; Shunichi Aikawa; Kentaro Adachi; Akira Tanaka; Takeshi Tokai; Yuichi Nakajima; Yasuhiko Yoshida; Shohei Sakuda; Makoto Kimura; Naoko Takahashi-Ando

  Journal of Natural Products 81 (4) 1041 - 1044 0163-3864 2018/04 [Refereed]
  
• Chitin degraded by chitinolytic enzymes induces crystal defects of calcites

  Hiroyuki Kintsu; Taiga Okumura; Lumi Negishi; Shinsuke Ifuku; Toshihiro Kogure; Shohei Sakuda; Michio Suzuki

  Biomineralization 375 - 381 2018 [Refereed]
  
• Intracellular superoxide level controlled by manganese superoxide dismutases affects trichothecene production in Fusarium graminearum

  Tomohiro Furukawa; Tomoya Yoshinari; Shohei Sakuda

  FEMS microbiology letters 364 (21) 0378-1097 2017/11 [Refereed]
  
• Structural and functional analyses of a TIMP and MMP in the ligament of Pinctada fucata

  Kazuki Kubota; Yasushi Tsuchihashi; Toshihiro Kogure; Kaoru Maeyama; Fumihiro Hattori; Shigeharu Kinoshita; Shohei Sakuda; Hiromichi Nagasawa; Etsuro Yoshimura; Michio Suzuki

  Journal of Structural Biology 199 (3) 216 - 224 1047-8477 2017/09 [Refereed]
  
• Crystal defects induced by chitin and chitinolytic enzymes in the prismatic layer of Pinctada fucata

  Hiroyuki Kintsu; Taiga Okumura; Lumi Negishi; Shinsuke Ifuku; Toshihiro Kogure; Shohei Sakuda; Michio Suzuki

  Biochemical and Biophysical Research Communications 489 (2) 89 - 95 0006-291X 2017/07 [Refereed]
  
• The mode of action of cyclo(L-Ala-L-Pro) in inhibiting aflatoxin production of Aspergillus flavus

  Kurin Iimura; Tomohiro Furukawa; Toshiyoshi Yamamoto; Lumi Negishi; Michio Suzuki; Shohei Sakuda

  Toxins 9 (7) 2072-6651 2017/07 [Refereed]
  
• Molecular cloning and functional analysis of chitinases in the fresh water snail, Lymnaea stagnalis

  Mai Yonezawa; Shohei Sakuda; Etsuro Yoshimura; Michio Suzuki

  Journal of Structural Biology 196 (2) 107 - 118 1047-8477 2016/11 [Refereed]
  
• Synthesis of CdSe quantum dots using Fusarium oxysporum

  Takaaki Yamaguchi; Yoshijiro Tsuruda; Tomohiro Furukawa; Lumi Negishi; Yuki Imura; Shohei Sakuda; Etsuro Yoshimura; Michio Suzuki

  Materials 9 (10) 1996-1944 2016/10 [Refereed]
  
• Inhibitory activities of alkyl syringates and related compounds on aflatoxin production

  Tomohiro Furukawa; Kurin Iimura; Taichi Kimura; Toshiyoshi Yamamoto; Shohei Sakuda

  Toxins 8 (6) 2072-6651 2016/06 [Refereed]
  
• Microstructure of iridescence-lacking pearl formed in Pinctada fucata

  Michio Suzuki; Hiroki Mukai; Hideo Aoki; Etsuro Yoshimura; Shohei Sakuda; Hiromichi Nagasawa; Toshihiro Kogure

  Journal of Crystal Growth 433 148 - 152 0022-0248 2016/01 [Refereed]
  
• Search for aflatoxin and trichothecene production inhibitors and analysis of their modes of action

  Shohei Sakuda; Tomoya Yoshinari; Tomohiro Furukawa; Usuma Jermnak; Keiko Takagi; Kurin Iimura; Toshiyoshi Yamamoto; Michio Suzuki; Hiromichi Nagasawa

  Bioscience, Biotechnology and Biochemistry 80 (1) 43 - 54 0916-8451 2016
• A class III chitinase without disulfide bonds from the fern, Pteris ryukyuensis: crystal structure and ligand-binding studies

  Yoshihito Kitaoku; Naoyuki Umemoto; Takayuki Ohnuma; Tomoyuki Numata; Toki Taira; Shohei Sakuda; Tamo Fukamizo

  Planta 242 (4) 895 - 907 0032-0935 2015/10 [Refereed]
  
• Precocene II, a trichothecene production inhibitor, binds to voltage-dependent anion channel and increases the superoxide level in mitochondria of fusarium graminearum

  Tomohiro Furukawa; Naoko Sakamoto; Michio Suzuki; Makoto Kimura; Hiromichi Nagasawa; Shohei Sakuda

  PLoS ONE 10 (8) 1932-6203 2015/08 [Refereed]
  
• Inhibition of the DNA polymerase and RNase H activities of HIV-1 reverse transcriptase and HIV-1 replication by Brasenia schreberi (Junsai) and Petasites japonicus (Fuki) components

  Tetsuro Hisayoshi; Mayu Shinomura; Kanta Yokokawa; Ikumi Kuze; Atsushi Konishi; Kumi Kawaji; Eiichi N. Kodama; Keishi Hata; Saori Takahashi; Satoru Nirasawa; Shohei Sakuda; Kiyoshi Yasukawa

  Journal of Natural Medicines 69 (3) 432 - 440 1340-3443 2015/07 [Refereed]
  
• Crystal structures and inhibitor binding properties of plant class v chitinases: The cycad enzyme exhibits unique structural and functional features

  Naoyuki Umemoto; Yuka Kanda; Takayuki Ohnuma; Takuo Osawa; Tomoyuki Numata; Shohei Sakuda; Toki Taira; Tamo Fukamizo

  Plant Journal 82 (1) 54 - 66 0960-7412 2015/04 [Refereed]
  
• Identification of Ligament Intra-Crystalline Peptide (LICP) from the Hinge Ligament of the Bivalve, Pinctada Fucata

  Michio Suzuki; Toshihiro Kogure; Shohei Sakuda; Hiromichi Nagasawa

  Marine Biotechnology 17 (2) 153 - 161 1436-2228 2015 [Refereed]
  
• Potential use and mode of action of the new strain Bacillus thuringiensis UM96 for the biological control of the grey mould phytopathogen Botrytis cinerea

  Sofía Martínez-Absalón; Daniel Rojas-Solís; Rocío Hernández-León; Cristina Prieto-Barajas; Ma del Carmen Orozco-Mosqueda; Juan José Peña-Cabriales; Shohei Sakuda; Eduardo Valencia-Cantero; Gustavo Santoyo

  Biocontrol Science and Technology 24 (12) 1349 - 1362 0958-3157 2014/12 [Refereed]
  
• Corrigendum to "Isolation of methyl syringate as a specific aflatoxin production inhibitor from the essential oil of Betula alba and aflatoxin production inhibitory activities of its related compounds."[Int. J. Food Microbiol. 153 (2012) 339-344]

  Usuma Jermnak; Tomoya Yoshinari; Yasumasa Sugiyama; Rie Tsuyuki; Hiromichi Nagasawa; Shohei Sakuda

  International Journal of Food Microbiology 187 83 - 83 0168-1605 2014/09 [Refereed]
  
• Dioctatin A is a strong inhibitor of aflatoxin production by Aspergillus parasiticus (vol 153, pg 2774, 2007)

  Tomoya Yoshinari; Tetsuo Akiyama; Keita Nakamura; Tatsuhiko Kondo; Yoshikazu Takahashi; Yasuhiko Muraoka; Yoshiaki Nonomura; Hiromichi Nagasawa; Shohei Sakuda

  MICROBIOLOGY-SGM 160 1545 - 1545 1350-0872 2014/07 [Refereed]
  
• Prevention of aflatoxin contamination by a soil bacterium of Stenotrophomonas sp. that produces aflatoxin production inhibitors (vol 159, pg 902, 2013)

  Usuma Jermnak; Amara Chinaphuti; Amnart Poapolathep; Ryo Kawai; Hiromichi Nagasawa; Shohei Sakuda

  MICROBIOLOGY-SGM 160 1546 - 1546 1350-0872 2014/07 [Refereed]
  
• Dioctatin A is a strong inhibitor of aflatoxin production by Aspergillus parasiticus (vol 153, pg 2774, 2007)

  Tomoya Yoshinari; Tetsuo Akiyama; Keita Nakamura; Tatsuhiko Kondo; Yoshikazu Takahashi; Yasuhiko Muraoka; Yoshiaki Nonomura; Hiromichi Nagasawa; Shohei Sakuda

  MICROBIOLOGY-SGM 160 1545 - 1545 1350-0872 2014/07 [Refereed]
  
• Two-way traffic of glycoside hydrolase family 18 processive chitinases on crystalline chitin

  Kiyohiko Igarashi; Takayuki Uchihashi; Taku Uchiyama; Hayuki Sugimoto; Masahisa Wada; Kazushi Suzuki; Shohei Sakuda; Toshio Ando; Takeshi Watanabe; Masahiro Samejima

  Nature Communications 5 2041-1723 2014/06 [Refereed]
  
• Structural determination of a nivalenol glucoside and development of an analytical method for the simultaneous determination of nivalenol and deoxynivalenol, and their glucosides, in wheat

  Tomoya Yoshinari; Shohei Sakuda; Kazuo Furihata; Hiroko Furusawa; Takahiro Ohnishi; Yoshiko Sugita-Konishi; Naoto Ishizaki; Jun Terajima

  Journal of Agricultural and Food Chemistry 62 (5) 1174 - 1180 0021-8561 2014/02 [Refereed]
  
• Identification of the allosamidin-releasing factor in allosamidin-producing Streptomyces

  Shigeo Suzuki; Hiromichi Nagasawa; Shohei Sakuda

  Journal of Antibiotics 67 (2) 195 - 197 0021-8820 2014/02 [Refereed]
  
• Targeting AMCase reduces esophageal eosinophilic inflammation and remodeling in a mouse model of egg induced eosinophilic esophagitis

  Jae Youn Cho; Peter Rosenthal; Marina Miller; Alexa Pham; Seema Aceves; Shohei Sakuda; David H. Broide

  International Immunopharmacology 18 (1) 35 - 42 1567-5769 2014 [Refereed]
  
• Inhibitory effects of respiration inhibitors on aflatoxin production

  Shohei Sakuda; Diyan Febri Prabowo; Keiko Takagi; Kazuro Shiomi; Mihoko Mori; Satoshi Omura; Hiromichi Nagasawa

  Toxins 6 (4) 1193 - 1200 2072-6651 2014 [Refereed]
  
• Correlation of ATP citrate lyase and acetyl CoA levels with trichothecene production in Fusarium graminearum.

  Naoko Sakamoto; Rie Tsuyuki; Tomoya Yoshinari; Jermnak Usuma; Tomohiro Furukawa; Hiromichi Nagasawa; Shohei Sakuda

  Toxins 5 (11) 2258 - 2269 2072-6651 2013/11 [Refereed]
  
• Chronic Treatment with Novel GPR40 Agonists Improve Whole-Body Glucose Metabolism Based on the Glucose-Dependent Insulin Secretion

  Hirotsugu Tanaka; Shigeru Yoshida; Hiroyuki Oshima; Hideaki Minoura; Kenji Negoro; Takao Yamazaki; Shuichi Sakuda; Fumiyoshi Iwasaki; Tetsuo Matsui; Masayuki Shibasaki

  JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 346 (3) 443 - 452 0022-3565 2013/09 [Refereed]
  
• New metabolic pathway for converting blasticidin S in aspergillus flavus and inhibitory activity of aflatoxin production by blasticidin S metabolites

  Tomoya Yoshinari; Shohei Sakuda; Maiko Watanabe; Yoichi Kamata; Takahiro Ohnishi; Yoshiko Sugita-Konishi

  Journal of Agricultural and Food Chemistry 61 (33) 7925 - 7931 0021-8561 2013/08 [Refereed]
  
• Chitinase inhibition promotes atherosclerosis in hyperlipidemic mice

  Shiro Kitamoto; Kensuke Egashira; Toshihiro Ichiki; Xinbing Han; Sara McCurdy; Shohei Sakuda; Kenji Sunagawa; William A. Boisvert

  American Journal of Pathology 183 (1) 313 - 325 0002-9440 2013/07 [Refereed]
  
• Novel biological activities of allosamidins

  Shohei Sakuda; Hiromasa Inoue; Hiromichi Nagasawa

  Molecules 18 (6) 6952 - 6968 1420-3049 2013/06
• Prevention of aflatoxin contamination by a soil bacterium of Stenotrophomonas sp. that produces aflatoxin production inhibitors

  Usuma Jermnak; Amara Chinaphuti; Amnart Poapolathep; Ryo Kawai; Hiromichi Nagasawa; Shohei Sakuda

  Microbiology (United Kingdom) 159 (PART 5) 902 - 912 1350-0872 2013/05 [Refereed]
  
• Thermodynamic analysis of allosamidin binding to the human chitotriosidase

  Kristine Bistrup Eide; Silje Thoresen Lundmark; Shohei Sakuda; Morten Sørlie

  Thermochimica Acta 565 146 - 150 0040-6031 2013 [Refereed]
  
• Chitinase Inhibitor, Allosamidin, Accelerates Atherosclerotic Lesions in Hyperlipidemic Mice by Influencing M1/M2 Polarization and Cholesterol Metabolism in Macrophages

  Shiro Kitamoto; Kensuke Egashira; Toshihiro Ichiki; Xinbing Han; Shohei Sakuda; Kenji Sunagawa; William A. Boisvert

  CIRCULATION 126 (21) 0009-7322 2012/11 [Refereed]
  
• Isolation of methyl syringate as a specific aflatoxin production inhibitor from the essential oil of Betula alba and aflatoxin production inhibitory activities of its related compounds

  Usuma Jermnak; Tomoya Yoshinari; Yasumasa Sugiyama; Rie Tsuyuki; Hiromichi Nagasawa; Shohei Sakuda

  International Journal of Food Microbiology 153 (3) 339 - 344 0168-1605 2012/02 [Refereed]
  
• A cryptic antibiotic triggered by monensin

  Sho Ichi Amano; Tomomi Sakurai; Keisuke Endo; Hideaki Takano; Teruhiko Beppu; Kazuo Furihata; Shohei Sakuda; Kenji Ueda

  Journal of Antibiotics 64 (10) 703 - 703 0021-8820 2011/10
• Preparation of allosamidin and demethylallosamidin photoaffinity probes and analysis of allosamidin-binding proteins in asthmatic mice

  Yosuke Sato; Shigeo Suzuki; Seiko Muraoka; Naoya Kikuchi; Naotaka Noda; Takafumi Matsumoto; Hiromasa Inoue; Hiromichi Nagasawa; Shohei Sakuda

  Bioorganic and Medicinal Chemistry 19 (10) 3054 - 3059 0968-0896 2011/05 [Refereed]
  
• Glycolytic intermediates induce amorphous calcium carbonate formation in crustaceans

  Ai Sato; Seiji Nagasaka; Kazuo Furihata; Shinji Nagata; Isao Arai; Kazuko Saruwatari; Toshihiro Kogure; Shohei Sakuda; Hiromichi Nagasawa

  Nature Chemical Biology 7 (4) 197 - 199 1552-4450 2011/04 [Refereed]
  
• Enhancement of trichothecene production in fusarium graminearum by cobalt chloride

  Rie Tsuyuki; Tomoya Yoshinari; Naoko Sakamoto; Hiromichi Nagasawa; Shohei Sakuda

  Journal of Agricultural and Food Chemistry 59 (5) 1760 - 1766 0021-8561 2011/03 [Refereed]
  
• Aflatoxin and deoxynivalenol production inhibitors from natural products

  Shohei Sakuda

  JOURNAL OF PESTICIDE SCIENCE 36 (1) 115 - 118 1348-589X 2011 [Refereed]
  
• Endocrocin and its derivatives from the Japanese mealybug Planococcus kraunhiae

  Naoya Kikuchi; Mayumi Teshiba; Takafumi Tsutsumi; Ryosuke Fudou; Hiromichi Nagasawa; Shohei Sakuda

  Bioscience, Biotechnology and Biochemistry 75 (4) 764 - 767 0916-8451 2011 [Refereed]
  
• Effect of enzyme processivity on the efficacy of a competitive chitinase inhibitor

  Henrik Zakariassen; Laila Klemetsen; Shohei Sakuda; Gustav Vaaje-Kolstad; Kjell M. Vrum; Morten Sørlie; Vincent G.H. Eijsink

  Carbohydrate Polymers 82 (3) 779 - 785 0144-8617 2010/10 [Refereed]
  
• Promomycin, a polyether promoting antibiotic production in Streptomyces spp.

  Sho Ichi Amano; Tatsuya Morota; Yu Ki Kano; Hiroyuki Narita; Tohko Hashidzume; Setsuya Yamamoto; Kotaro Mizutani; Shohei Sakuda; Kazuo Furihata; Hatsumi Takano-Shiratori; Hideaki Takano; Teruhiko Beppu; Kenji Ueda

  Journal of Antibiotics 63 (8) 486 - 491 0021-8820 2010/08 [Refereed]
  
• Inhibitory activity of blasticidin A, a strong aflatoxin production inhibitor, on protein synthesis of yeast: Selective inhibition of aflatoxin production by protein synthesis inhibitors

  Tomoya Yoshinari; Yoichi Noda; Koji Yoda; Hiroshi Sezaki; Hiromichi Nagasawa; Shohei Sakuda

  Journal of Antibiotics 63 (6) 309 - 314 0021-8820 2010/06 [Refereed]
  
• The roles of three serratia marcescens chitinases in chitin conversion are reflected in different thermodynamic signatures of allosamidin binding

  Jamil Baban; Salima Fjeld; Shohei Sakuda; Vincent G.H. Eijsink; Morten Sorlie

  Journal of Physical Chemistry B 114 (18) 6144 - 6149 1520-6106 2010/05 [Refereed]
  
• Transglycosylation reaction catalyzed by a class V chitinase from cycad, Cycas revoluta: a study involving site-directed mutagenesis, HPLC, and real-time ESI-MS.

  Taira T; Fujiwara M; Dennhart N; Hayashi H; Onaga S; Ohnuma T; Letzel T; Sakuda S; Fukamizo T

  Biochimica et biophysica acta 1804 (4) 668 - 675 0006-3002 2010/04 [Refereed]
  
• Transglycosylation reaction catalyzed by a class V chitinase from cycad, Cycas revoluta: A study involving site-directed mutagenesis, HPLC, and real-time ESI-MS

  Toki Taira; Maho Fujiwara; Nicole Dennhart; Hiroko Hayashi; Shoko Onaga; Takayuki Ohnuma; Thomas Letzel; Shohei Sakuda; Tamo Fukamizo

  Biochimica et Biophysica Acta - Proteins and Proteomics 1804 (4) 668 - 675 1570-9639 2010/04 [Refereed]
  
• A Comparison of Pharmacokinetics between Humans and Monkeys

  Takafumi Akabane; Kenji Tabata; Keitaro Kadono; Shuichi Sakuda; Shigeyuki Terashita; Toshio Teramura

  DRUG METABOLISM AND DISPOSITION 38 (2) 308 - 316 0090-9556 2010/02 [Refereed]
  
• Natural aflatoxin inhibitors from medicinal plants

  Mehdi Razzaghi-Abyaneh; Masoomeh Shams-Ghahfarokhi; Mohammad Bagher Rezaee; Shohei Sakuda

  Mycotoxins in Food, Feed and Bioweapons Springer Berlin Heidelberg 329 - 352 2010 [Refereed]
  
• Demethylallosamidin, a chitinase inhibitor, suppresses airway inflammation and hyperresponsiveness

  Takafumi Matsumoto; Hiromasa Inoue; Yosuke Sato; Yoshihiro Kita; Takako Nakano; Naotaka Noda; Miyuki Eguchi-Tsuda; Atsushi Moriwaki; Keiko Kan-o; Koichiro Matsumoto; Takao Shimizu; Hiromichi Nagasawa; Shohei Sakuda; Yoichi Nakanishi

  Biochemical and Biophysical Research Communications 390 (1) 103 - 108 0006-291X 2009/12 [Refereed]
  
• Astaxanthin dirhamnoside, a new astaxanthin derivative produced by a radio-tolerant bacterium, sphingomonas astaxanthinifaciens

  Dalal Asker; Sho Ichi Amano; Kaori Morita; Kazuya Tamura; Shohei Sakuda; Naoya Kikuchi; Kazuo Furihata; Hiroshi Matsufuji; Teruhiko Beppu; Kenji Ueda

  Journal of Antibiotics 62 (7) 397 - 399 0021-8820 2009/07 [Refereed]
  
• Isolation and identification of precocenes and piperitone from essential oils as specific inhibitors of trichothecene production by Fusarium graminearum

  Atsushi Yaguchi; Tomoya Yoshinari; Rie Tsuyuki; Haruo Takahashi; Takashi Nakajima; Yoshiko Sugita-Konishi; Hiromichi Nagasawa; Shohei Sakuda

  Journal of Agricultural and Food Chemistry 57 (3) 846 - 851 0021-8561 2009/02 [Refereed]
  
• Chitinase gene expression in response to environmental stresses in arabidopsis thaliana: Chitinase inhibitor allosamidin enhances stress tolerance

  Yasuhiro Takenaka; Sachiko Nakano; Masahiro Tamoi; Shohei Sakuda; Tamo Fukamizo

  Bioscience, Biotechnology and Biochemistry 73 (5) 1066 - 1071 0916-8451 2009 [Refereed]
  
• Chitinase inhibitor allosamidin promotes chitinase production of Streptomyces generally

  Shigeo Suzuki; Eiyu Nakanishi; Keiko Furihata; Katsushiro Miyamoto; Hiroshi Tsujibo; Takeshi Watanabe; Yasuo Ohnishi; Sueharu Horinouchi; Hiromichi Nagasawa; Shohei Sakuda

  International Journal of Biological Macromolecules 43 (1) 13 - 19 0141-8130 2008/07 [Refereed]
  
• Spiroethers of German chamomile inhibit production of aflatoxin G 1 and trichothecene mycotoxin by inhibiting cytochrome P450 monooxygenases involved in their biosynthesis

  Tomoya Yoshinari; Atsushi Yaguchi; Naoko Takahashi-Ando; Makoto Kimura; Haruo Takahashi; Takashi Nakajima; Yoshiko Sugita-Konishi; Hiromichi Nagasawa; Shohei Sakuda

  FEMS Microbiology Letters 284 (2) 184 - 190 0378-1097 2008/07 [Refereed]
  
• Inhibitory effects of Satureja hortensis L. essential oil on growth and aflatoxin production by Aspergillus parasiticus

  Mehdi Razzaghi-Abyaneh; Masoomeh Shams-Ghahfarokhi; Tomoya Yoshinari; Mohammad Bagher Rezaee; Kamkar Jaimand; Hiromichi Nagasawa; Shohei Sakuda

  International Journal of Food Microbiology 123 (3) 228 - 233 0168-1605 2008/04 [Refereed]
  
• Thermodynamic analysis of allosamidin binding to a family 18 chitinase

  F. Henning Cederkvist; Silje F. Saua; Vigdis Karlsen; Shohei Sakuda; Vincent G.H. Eijsink; Morten Sørlie

  Biochemistry 46 (43) 12347 - 12354 0006-2960 2007/10 [Refereed]
  
• Absolute structure of prunustatin A, a novel GRP78 molecular chaperone down-regulator

  Yukiko Umeda; Kazuo Furihata; Shohei Sakuda; Hiromichi Nagasawa; Ken Ishigami; Hidenori Watanabe; Miho Izumikawa; Motoki Takagi; Takayuki Doi; Yoichi Nakao; Kazuo Shin-ya

  Organic Letters 9 (21) 4239 - 4242 1523-7060 2007/10 [Refereed]
  
• Dioctatin A is a strong inhibitor of aflatoxin production by Aspergillus parasiticus

  Tomoya Yoshinari; Tetsuo Akiyama; Keita Nakamura; Tatsuhiko Kondo; Yoshikazu Takahashi; Yasuhiko Muraoka; Yoshiaki Nonomura; Hiromichi Nagasawa; Shohei Sakuda

  Microbiology 153 (8) 2774 - 2780 1350-0872 2007/08 [Refereed]
  
• A novel highly acidic polysaccharide with inhibitory activity on calcification from the calcified scale "coccolith" of a coccolithophorid alga, Pleurochrysis haptonemofera

  Noriaki Ozaki; Shohei Sakuda; Hiromichi Nagasawa

  Biochemical and Biophysical Research Communications 357 (4) 1172 - 1176 0006-291X 2007/06 [Refereed]
  
• Assignment of the absolute configuration of blasticidin A and revision of that of aflastatin A

  Shohei Sakuda; Nobuaki Matsumori; Kazuo Furihata; Hiromichi Nagasawa

  Tetrahedron Letters 48 (14) 2527 - 2531 0040-4039 2007/04 [Refereed]
  
• Identification of chitin in the prismatic layer of the shell and a chitin synthase gene from the Japanese pearl oyster, Pinctada fucata

  Michio Suzuki; Shohei Sakuda; Hiromichi Nagasawa

  Bioscience, Biotechnology and Biochemistry 71 (7) 1735 - 1744 0916-8451 2007 [Refereed]
  
• Dillapiol and apiol as specific inhibitors of the biosynthesis of aflatoxin G1 in Aspergillus parasiticus

  Mehdi Razzaghi-Abyaneh; Tomoya Yoshinari; Masoomeh Shams-Ghahfarokhi; Mohammad Bagher Rezaee; Hiromichi Nagasawa; Shohei Sakuda

  Bioscience, Biotechnology and Biochemistry 71 (9) 2329 - 2332 0916-8451 2007 [Refereed]
  
• Novel benzene ring biosynthesis from C-3 and C-4 primary metabolites by two enzymes

  Hirokazu Suzuki; Yasuo Ohnishi; Yasuhide Furusho; Shohei Sakuda; Sueharu Horinouchi

  JOURNAL OF BIOLOGICAL CHEMISTRY 281 (48) 36944 - 36951 0021-9258 2006/12 [Refereed]
  
• Novel benzene ring biosynthesis from C3 and C4 primary metabolites by two enzymes

  Hirokazu Suzuki; Yasuo Ohnishi; Yasuhide Furusho; Shohei Sakuda; Sueharu Horinouchi

  Journal of Biological Chemistry 281 (48) 36944 - 36951 0021-9258 2006/12 [Refereed]
  
• Chitinase inhibitor allosamidin is a signal molecule for chitinase production in its producing Streptomyces: II. Mechanism for regulation of chitinase production by allosamidin through a two-component regulatory system

  Shigeo Suzuki; Eiyu Nakanishi; Tsuyoshi Ohira; Ryu Kawachi; Yasuo Ohnishi; Sueharu Horinouchi; Hiromichi Nagasawa; Shohei Sakuda

  Journal of Antibiotics 59 (7) 410 - 417 0021-8820 2006/07 [Refereed]
  
• Chitinase inhibitor allosamidin is a signal molecule for chitinase production in its producing Streptomyces: I. Analysis of the chitinase whose production is promoted by allosamidin and growth accelerating activity of allosamidin

  Shigeo Suzuki; Eiyu Nakanishi; Tsuyoshi Ohira; Ryu Kawachi; Hiromichi Nagasawa; Shohei Sakuda

  Journal of Antibiotics 59 (7) 402 - 409 0021-8820 2006/07 [Refereed]
  
• Marked species differences in the bioavailability of midazolam in cynomolgus monkeys and humans

  S. Sakuda; T. Akabane; T. Teramura

  XENOBIOTICA 36 (4) 331 - 340 0049-8254 2006/04 [Refereed]
  
• Desferrioxamine E produced by Streptomyces griseus stimulates growth and development of Streptomyces tanashiensis

  Kazuki Yamanaka; Hiroaki Oikawa; Hiro Omi Ogawa; Kuniaki Hosono; Fumie Shinmachi; Hideaki Takano; Shohei Sakuda; Teruhiko Beppu; Kenji Ueda

  Microbiology 151 (9) 2899 - 2905 1350-0872 2005/09 [Refereed]
  
• Comparative activities of glutathione-S-transferase and dialdehyde reductase toward aflatoxin B1 in livers of experimental and farm animals

  P. Tulayakul; S. Sakuda; K. S. Dong; S. Kumagai

  Toxicon 46 (2) 204 - 209 0041-0101 2005/08 [Refereed]
  
• Prunustatin A, a novel GRP78 molecular chaperone down-regulator isolated from Streptomyces violaceoniger

  Yukiko Umeda; Shuhei Chijiwa; Kazuo Furihata; Keiko Furihata; Shohei Sakuda; Hiromichi Nagasawa; Hidenori Watanabe; Kazuo Shin-Ya

  Journal of Antibiotics 58 (3) 206 - 209 0021-8820 2005/03 [Refereed]
  
• Conversion from arenes having a benzene ring to those having a picolinic acid by simple growing cell reactions using Escherichia coli that expressed the six bacterial genes involved in biphenyl catabolism

  Kazutoshi Shindo; Ayako Osawa; Ryoko Nakamura; Yukiko Kagiyama; Shohei Sakuda; Yoshikazu Shizuri; Kensuke Furukawa; Norihiko Misawa

  Journal of the American Chemical Society 126 (46) 15042 - 15043 0002-7863 2004/11 [Refereed]
  
• Inhibitory effect of a bitter melon extract on the P-glycoprotein activity in intestinal Caco-2 cells

  Tomoko Konishi; Hideo Satsu; Yasuo Hatsugai; Koichi Aizawa; Takahiro Inakuma; Shinji Nagata; Sho Hei Sakuda; Hiromichi Nagasawa; Makoto Shimizu

  British Journal of Pharmacology 143 (3) 379 - 387 0007-1188 2004/10 [Refereed]
  
• Kinetic analysis of a chitinase from red sea bream, Pagrus major

  Shuji Karasuda; Kosuke Yamamoto; Michiko Kono; Shohei Sakuda; Daizo Koga

  Bioscience, Biotechnology and Biochemistry 68 (6) 1338 - 1344 0916-8451 2004/06 [Refereed]
  
• Structures of grixazone A and B, A-Factor-dependent yellow pigments produced under phosphate depletion by Streptomyces griseus

  Yasuo Ohnishi; Yasuhide Furusho; Tatsuichiro Higashi; Hyo Kon Chun; Kazuo Furihata; Shohei Sakuda; Sueharu Horinouchi

  Journal of Antibiotics 57 (3) 218 - 223 0021-8820 2004/03 [Refereed]
  
• Absolute configuration of a polyol fragment of blasticidin A, a specific inhibitor of aflatoxin production

  Shohei Sakuda; Hiroyuki Ikeda; Takefumi Nakamura; Hiromichi Nagasawa

  Bioscience, Biotechnology and Biochemistry 68 (2) 407 - 412 0916-8451 2004/02 [Refereed]
  
• Isolation of Indole-3-Aldehyde As a Growth Inhibitor of Legionella pneumophila from Diaion HP-20 Resins Used to Culture the Bacteria

  Hiroaki Inoue; Yousuke Yajima; Genji Kawano; Hiromichi Nagasawa; Shohei Sakuda

  Biocontrol Science 9 (42371) 39 - 41 1342-4815 2004 [Refereed]
  
• A novel acidic polysaccharide from coccoliths of the coccolithophorid alga, Pleurochrysis carterae.

  N. Ozaki; M. Okazaki; S. Sakuda; H. Nagasawa

  Biominerlization: formation, diversity, evolution and application (Kobayashi, I and Ozawa, H eds.), Tokai University Press, Tokyo. 58 - 61 2004 [Refereed]
  
• Structural and functional diversity of acidic polysaccharides from various species of coccolithphorid algae.

  N. Ozaki; M. Okazaki; T. Kogure; S. Sakuda; H. Nagasawa

  Thalassas 20 59 - 68 2004 [Refereed]
  
• Possible involvement of carbonic anhydrase in the formation of barnacle shell.

  M. Fukushima; N. Ozaki; S. Sakuda; H. Nagasawa

  Biominerlization: formation, diversity, evolution and application (Kobayashi, I and Ozawa, H eds.), Tokai University Press, Tokyo. 157 - 160 2004 [Refereed]
  
• A bitter melon extract inhibits the P-glycoprotein activity in intestinal Caco-2 cells: Monoglyceride as an active compound

  Tomoko Konishi; Hideo Satsu; Yasuo Hatsugai; Koichi Aizawa; Takahiro Inakuma; Shinji Nagata; Sho Hei Sakuda; Hiromichi Nagasawa; Makoto Shimizu

  BioFactors 22 (1-4) 71 - 74 0951-6433 2004 [Refereed]
  
• Development of a genetic system in chitinase-producing Streptomyces and the application of an allosamidin-insensitive chitinase gene to homologous overexpression

  Ryu Kawachi; Yuko Koike; Yumi Watanabe; Toshiyuki Nishio; Shohei Sakuda; Hiromichi Nagasawa; Tadatake Oku

  Applied Biochemistry and Biotechnology - Part B Molecular Biotechnology 26 (3) 179 - 185 1073-6085 2004 [Refereed]
  
• Expression of ephrin-B1 in hepatocellular carcinoma: possible involvement in neovascularization

  Y Sawai; S Tamura; K Fukui; N Ito; K Imanaka; A Saeki; S Sakuda; S Kiso; Y Matsuzawa

  JOURNAL OF HEPATOLOGY 39 (6) 991 - 996 0168-8278 2003/12 [Refereed]
  
• Nucleotide sequences of genes encoding allosamidin-sensitive and -insensitive chitinases produced by allosamidin-producing Streptomyces

  Hiroshi Matsuura; Susumu Okamoto; Sarintip Anamnart; Qiuqi Wang; Ze Yang Zhou; Takuya Nihira; Yasuhiro Yamada; Tomohisa Kuzuyama; Haruo Seto; Jiro Nakayama; Akinori Suzuki; Hiromichi Nagasawa; Shohei Sakuda

  Bioscience, Biotechnology and Biochemistry 67 (9) 2002 - 2005 0916-8451 2003/09 [Refereed]
  
• Isolation of abikoviromycin and dihydroabikoviromycin as inhibitors of polyketide synthase involved in melanin biosynthesis by Colletotrichum lagenarium

  Hiroki Maruyama; Susumu Okamoto; Yasuyuki Kubo; Gento Tsuji; Isao Fujii; Yutaka Ebizuka; Keiko Furihata; Yoichi Hayakawa; Hiromichi Nagasawa; Shohei Sakuda

  Journal of Antibiotics 56 (9) 801 - 804 0021-8820 2003/09 [Refereed]
  
• Crystal structures of allosamidin derivatives in complex with human macrophage chitinase

  Francesco V. Rao; Douglas R. Houston; Rolf G. Boot; Johannes M.F.G. Aerts; Shohei Sakuda; Daan M.F. Van Aalten

  Journal of Biological Chemistry 278 (22) 20110 - 20116 0021-9258 2003/05 [Refereed]
  
• Isolation and synthesis of a new bioactive ellagic acid derivative from Combretum yunnanensis

  Yukihiro Asami; Takashi Ogura; Noboru Otake; Toshio Nishimura; Yao Xinsheng; Takashi Sakurai; Hiromichi Nagasawa; Shohei Sakuda; Kuniaki Tatsuta

  Journal of Natural Products 66 (5) 729 - 731 0163-3864 2003/05 [Refereed]
  
• Mode of action of aflastatin A and blasticidin A, inhibitors of mycotoxin production

  SAKUDA Shohei; KONDO Tatsuhiko; YOSHINARI Tomoya; NAGASAWA Hiromichi

  JSM Mycotoxins Japanese Society of Mycotoxicology 2003 (3) 99 - 105 0285-1466 2003
• Isolation of elemental sulfur as a self-growth-inhibiting substance produced by Legionella pneumophila

  Hiroaki Inoue; Genji Kawano; Hiromichi Nagasawa; Shohei Sakuda

  Applied and Environmental Microbiology 68 (10) 4809 - 4811 0099-2240 2002/10 [Refereed]
  
• NF-kappaB activation in non-parenchymal liver cells after partial hepatectomy in rats: possible involvement in expression of heparin-binding epidermal growth factor-like growth factor.

  Sakuda S; Tamura S; Yamada A; Miyagawa J; Yamamoto K; Kiso S; Ito N; Higashiyama S; Taniguchi N; Kawata S; Matsuzawa Y

  Journal of hepatology 2002/04 [Refereed]
  
• Assamicin I and II, novel triterpenoid saponins with insulin-like activity from Aesculus assamica Griff.

  Takashi Sakurai; Toshio Nishimura; Noboru Otake; Yao Xinsheng; Keiichi Abe; Mitsuhiro Zeida; Hiromichi Nagasawa; Shohei Sakuda

  Bioorganic and Medicinal Chemistry Letters 12 (5) 807 - 810 0960-894X 2002/03 [Refereed]
  
• Activation of signal transducer and activator transcription 3 and expression of suppressor of cytokine signal 1 during liver regeneration in rats.

  Sakuda S; Tamura S; Yamada A; Miyagawa Ji; Yamamoto K; Kiso S; Ito N; Imanaka K; Wada A; Naka T; Kishimoto T; Kawata S; Matsuzawa Y

  Journal of hepatology 2002/03 [Refereed]
  
• Isolation and characterization of 2-nitroimidazole produced by Streptomyces species as an inhibitor of both carbonic anhydrase and shell formation in the barnacle Balanus amphitrite

  Mari Fukushima; Noriaki Ozaki; Hiroyuki Ikeda; Keiko Furihata; Yoichi Hayakawa; Shohei Sakuda; Hiromichi Nagasawa

  Marine Biotechnology 4 (2) 103 - 110 1436-2228 2002 [Refereed]
  
• Biosynthesis of the trehalase inhibitor trehazolin

  Yasumasa Sugiyama; Hiromichi Nagasawa; Akinori Suzuki; Shohei Sakuda

  Journal of Antibiotics 55 (3) 263 - 269 0021-8820 2002 [Refereed]
  
• Studies on allosamidin and aflastatin, novel inhibitors of important metabolic pathways, from microorganisms

  Shohei Sakuda

  Japanese Journal of Antibiotics 55 (3) 311 - 318 0368-2781 2002 [Refereed]
  
• Expression and Secretion of a Larval-specific Chitinase (Family 18 Glycosyl Hydrolase) by the Infective Stages of the Parasitic Nematode, Onchocerca volvulus

  Yang Wu; Gillian Egerton; Anthony P. Underwood; Shohei Sakuda; Albert E. Bianco

  Journal of Biological Chemistry 276 (45) 42557 - 42564 0021-9258 2001/11 [Refereed]
  
• Isolation and some characterization of an acidic polysaccharide with anti-calcification activity from coccoliths of a marine alga, Pleurochrysis carterae

  Noriaki Ozaki; Shohei Sakuda; Hiromichi Nagasawa

  Bioscience, Biotechnology and Biochemistry 65 (10) 2330 - 2333 0916-8451 2001/10 [Refereed]
  
• Chemical synthesis and biological activity of the gelatinase biosynthesis-activating pheromone of Enterococcus faecalis and its analogs

  J Nakayama; Y Cao; T Horii; S Sakuda; H Nagasawa

  BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY 65 (10) 2322 - 2325 0916-8451 2001/10 [Refereed]
  
• Inhibitory effect of aflastatin A on melanin biosynthesis by Colletotrichum lagenarium

  S Okamoto; M Sakurada; Y Kubo; G Tsuji; Fujii, I; Y Ebizuka; M Ono; H Nagasawa; S Sakuda

  MICROBIOLOGY-SGM 147 2623 - 2628 1350-0872 2001/09 [Refereed]
  
• Effects of aflastatin A, an inhibitor of aflatoxin production, on aflatoxin biosynthetic pathway and glucose metabolism in Aspergillus parasiticus

  T Kondo; M Sakurada; S Okamoto; M Ono; H Tsukigi; A Suzuki; H Nagasawa; S Sakuda

  JOURNAL OF ANTIBIOTICS 54 (8) 650 - 657 0021-8820 2001/08 [Refereed]
  
• Gelatinase biosynthesis-activating pheromone: a peptide lactone that mediates a quorum sensing in Enterococcus faecalis

  J Nakayama; Y Cao; T Horii; S Sakuda; ADL Akkermans; WM de Vos; H Nagasawa

  MOLECULAR MICROBIOLOGY 41 (1) 145 - 154 0950-382X 2001/07 [Refereed]
  
• Chemical structure of a novel aminophospholipid from Hydrogenobacter thermophilus strain TK-6

  Jun Ichiro Yoshino; Yusumasa Sugiyama; Shohei Sakuda; Tohru Kodama; Hiromichi Nagasawa; Masaharu Ishii; Yasuo Igarashi

  Journal of Bacteriology 183 (21) 6302 - 6304 0021-9193 2001 [Refereed]
  
• Aflastatins: New streptomyces metabolites that inhibit aflatoxin biosynthesis

  Shohei Sakuda; Makoto Ono; Hiroyuki Ikeda; Masaru Sakurada; Jiro Nakayama; Akinori Suzuki; Akira Isogai

  Biologically Active Natural Products: Agrochemicals 185 - 200 1999/01 [Refereed]
  
• Preparation of biotinylated allosamidins with strong chitinase inhibitory activities

  S Sakuda; M Sakurada

  BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 8 (21) 2987 - 2990 0960-894X 1998/11 [Refereed]
  
• Molecular mechanism of peptide-specific pheromone signaling in Enterococcus faecalis: Functions of pheromone receptor TraA and pheromone-binding protein TraC encoded by plasmid pPD1

  J Nakayama; Y Takanami; T Horii; S Sakuda; A Suzuki

  JOURNAL OF BACTERIOLOGY 180 (3) 449 - 456 0021-9193 1998/02 [Refereed]
  
• Morphological Changes in Insect BM-N4 Cells Induced by Nocardamine

  Ken Matsubara; Shohei Sakuda; Tatsuhiko Kondo; Minoru Tanaka; Akinori Suzuki; Toshio Nishimura

  Bioscience, Biotechnology and Biochemistry 62 (10) 2049 - 2051 1347-6947 1998 [Refereed]
  
• Mycothiol, 1-O-(2'-[N-acetyl-L-cysteinyl]amido-2'-deoxy-alpha-D-glucopyranosyl)-D-myo-inositol, is the factor of NAD/factor-dependent formaldehyde dehydrogenase

  M MissetSmits; PW vanOphem; S Sakuda; JA Duine

  FEBS LETTERS 409 (2) 221 - 222 0014-5793 1997/06 [Refereed]
  
• Effect of demethylation on the chitinase inhibitory activity of allosamidin

  KD Spindler; M SpindlerBarth; S Sakuda

  ARCHIVES OF INSECT BIOCHEMISTRY AND PHYSIOLOGY 36 (3) 223 - 227 0739-4462 1997 [Refereed]
  
• Stereospecific reduction of virginiamycin M(1) as the virginiamycin resistance pathway in Streptomyces virginiae

  CK Lee; M Minami; S Sakuda; T Nihira; Y Yamada

  ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 40 (3) 595 - 601 0066-4804 1996/03 [Refereed]
  
• STRUCTURE OF PATULODIN, A NEW AZAPHILONE EPOXIDE, PRODUCED BY PENICILLIUM-URTICAE

  S SAKUDA; Y OTSUBO; Y YAMADA

  JOURNAL OF ANTIBIOTICS 48 (1) 85 - 86 0021-8820 1995/01 [Refereed]
  
• BIOSYNTHETIC-STUDIES ON VIRGINIAE BUTANOLIDE-A, A BUTYROLACTONE AUTOREGULATOR FROM STREPTOMYCES .2. PREPARATION OF POSSIBLE BIOSYNTHETIC INTERMEDIATES AND CONVERSION EXPERIMENTS IN A CELL-FREE SYSTEM

  S SAKUDA; S TANAKA; K MIZUNO; O SUKCHAROEN; T NIHIRA; Y YAMADA

  JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 (19) 2309 - 2315 0300-922X 1993/10 [Refereed]
  
• NEW VIRGINIAE BUTANOLIDES FROM STREPTOMYCES-VIRGINIAE

  K KONDO; Y HIGUCHI; S SAKUDA; T NIHIRA; Y YAMADA

  JOURNAL OF ANTIBIOTICS 42 (12) 1873 - 1876 0021-8820 1989/12 [Refereed]
  
• ISOLATION AND STRUCTURE OF A NEW BUTYROLACTONE AUTOREGULATOR FROM STREPTOMYCES SP FRI-5

  K SATO; T NIHIRA; S SAKUDA; M YANAGIMOTO; Y YAMADA

  JOURNAL OF FERMENTATION AND BIOENGINEERING 68 (3) 170 - 173 0922-338X 1989 [Refereed]
  
• BIOSYNTHESIS OF THE MACROLIDE ANTIBIOTIC PATULOLIDES BY PENICILLIUM-URTICAE S11R59 - IDENTIFICATION OF THE ORIGIN OF CARBON-ATOMS BY C-13 NMR-SPECTROSCOPY

  D RODPHAYA; T NIHIRA; S SAKUDA; Y YAMADA

  JOURNAL OF ANTIBIOTICS 41 (11) 1649 - 1658 0021-8820 1988/11 [Refereed]
  
• PC23 ALLOSAMIDINS, INSECT CHITINASE INHIBITORS, PRODUCED BY MICROBES

  Isogai A.; Sakuda S.; Matsumoto S.; Koga D.; Koseki K.; Kodama H.; Suzuki A.

  International Symposium on the Chemistry of Natural Products Symposium on the chemistry of natural products 1988 479 - 479 1988/05
• ISOLATION AND STRUCTURE OF ISOBUTYRYLLEUCANICIDIN PRODUCED BY STREPTOMYCES-HALSTEDII

  S SAKUDA; A ISOGAI; S MATSUMOTO; M OGURA; K FURIHATA; H SETO; A SUZUKI

  AGRICULTURAL AND BIOLOGICAL CHEMISTRY 51 (10) 2841 - 2842 0002-1369 1987/10 [Refereed]
  
• SPECIFIC-INHIBITION OF BOMBYX-MORI CHITINASE BY ALLOSAMIDIN

  D KOGA; A ISOGAI; S SAKUDA; S MATSUMOTO; A SUZUKI; S KIMURA; A IDE

  AGRICULTURAL AND BIOLOGICAL CHEMISTRY 51 (2) 471 - 476 0002-1369 1987/02 [Refereed]
  
• Screening search for plant growth regulators from microbial metabolites.

  Isogai A; Sakuda S; Nakayama J; Washizu M; Shindou K; Watanabe S; Suzuki A

  Proceedings annual meeting - Plant Growth Regulator Society of America. 1987/01 [Refereed]
  
• THE STRUCTURE OF ALLOSAMIDIN, A NOVEL INSECT CHITINASE INHIBITOR, PRODUCED BY STREPTOMYCES SP

  S SAKUDA; A ISOGAI; S MATSUMOTO; A SUZUKI; K KOSEKI

  TETRAHEDRON LETTERS 27 (22) 2475 - 2478 0040-4039 1986 [Refereed]
  
• SEARCH FOR MICROBIAL INSECT GROWTH-REGULATORS - L-ALANOSINE AS AN ECDYSIS INHIBITOR

  S MATSUMOTO; S SAKUDA; A ISOGAI; A SUZUKI

  AGRICULTURAL AND BIOLOGICAL CHEMISTRY 48 (3) 827 - 828 0002-1369 1984 [Refereed]
  

Books etc

• Aflastatins : New streptomyces metabolites that inhibit aflatoxin(共著)

  Biologically active natural products : agrochemicals 1999

Conference Activities & Talks

• Chemical biology in mycotoxin research

  Shohei Sakuda

  International Symposium of Mycotoxicology 2022 & International Conference of Mycotoxicology and Food Security  2022/09
• Mycotoxin Researchers in Japan

  作田 庄平

  Mycokey Conference Italy-2020  2020/03
• Japan in focus: a close look at regulatory issues for mycotoxins and recent advance in mycotoxin research

  SAKUDA Shohei

  WMFmeetsASIA  2020/01
• Aflatoxin production inhibitors –Two decades from aflastatin A

  SAKUDA Shohei

  International Conference of Mycotoxicology and Food Security  2019/02
• Key molecules in primary metabolism for mycotoxin production

  SAKUDA Shohei

  2nd Mycokey International Conference  2018/09
• Recent advances in allosamidin research

  SAKUDA Shohei

  14th International Chitin and Chitosan Conference  2018/08
• Modes of action and application of aflatoxin and trichothecene production inhibitors

  SAKUDA Shohei

  1st APEC Conference on Mycotoxin Prevention and Control in Food and Feed Commodities in Asia - Pacific Region  2017/10
• Function of allosamidin in environment

  SAKUDA Shohei

  4th China International and Cross-strait Chitin and Chitosan Symposium  2017/10
• Search for mycotoxin production inhibitors and their modes of action

  SAKUDA Shohei

  1st Chinese Mycotoxin Conference  2016/06
• Mycotoxin production inhibitors and their mode of action

  SAKUDA Shohei

  International Mycotoxin Conference 2014  2014/05
• Novel biological activities of allosamidin

  SAKUDA Shohei

  10th Asia Pacific Chitin & Chitosan Symposium,  2013/10
• Prevention of mycotoxin contamination using mycotoxin production inhibitors

  SAKUDA Shohei

  International Conference on Mycological Aspect of Food and Feed Safety  2013/07

MISC

• Academic information of puberulic acid detected in red yeast rice supplements

  木村真; 吉成知也; 作田庄平; 須賀晴久; 福山朋季; 小西良子  JSM Mycotoxins  74-  (2)  2024
• Study on the Mechanisms of Mycotoxin Production

  作田庄平; 古川智宏  Bio Industry  41-  (6)  2024
• プロテインチロシンホスファターゼ阻害剤blasticidin Aおよびdephostatinによるアフラトキシン生産阻害(Inhibition of aflatoxin production by protein tyrosine phosphatase inhibitors, blasticidin A and dephostatin)

  井之口 曜; 古川 智宏; 吉成 知也; 作田 庄平  JSM Mycotoxins  69-  (2)  71  -79  2019/07
• 外部から加えたスーパーオキシド消去酵素によるアフラトキシン生産の制御機構

  古川智宏; 作田庄平  日本農芸化学会大会講演要旨集(Web)  2019-  ROMBUNNO.1D1a06 (WEB ONLY)  2019/03
• Progress in bioorganic chemistry on allosamidin and aflastatin, microbial metabolites that control metabolism

  作田 庄平  The Japanese journal of antibiotics  72-  (1)  31  -40  2019/03
• Progress in bioorganic chemistry on allosamidin and aflastatin, microbial metabolites that control metabolism

  SAKUDA Shohei  The Japanese Journal of Antibiotics  72-  (1)  31  -40  2019/03
• cyclo(L‐Ala‐L‐Pro)のアフラトキシン生産阻害機構の解明

  飯村九林; 古川智宏; 山本利義; 根岸瑠美; 鈴木道生; 作田庄平  日本農芸化学会大会講演要旨集(Web)  2018-  ROMBUNNO.3A15p05 (WEB ONLY)  2018/03
• アフラトキシン生産阻害物質dioctatinの引き起こすClpプロテアーゼの異常活性

  古川智宏; 片山秀和; 村瀬浩司; 根岸瑠美; 鈴木道生; 高山誠司; 作田庄平  日本農芸化学会大会講演要旨集(Web)  2018-  ROMBUNNO.3A18a05 (WEB ONLY)  2018/03
• Paenibacillus sp.PS‐1の生産するアフラトキシン生産阻害物質

  YANG Xiaoran; 古川智宏; 飯村九林; 高山誠司; 作田庄平  日本農芸化学会大会講演要旨集(Web)  2018-  ROMBUNNO.3A18a04 (WEB ONLY)  2018/03
• 二枚貝稜柱層における結晶欠陥形成因子の比較

  近都浩之; 奥村大河; 根岸瑠美; 永田宏次; 小暮敏博; 作田庄平; 鈴木道生  日本農芸化学会大会講演要旨集(Web)  2018-  2018
• Report of the 1^st APEC Mycotoxin Conference

  Sakuda Shohei  JSM Mycotoxins  68-  (1)  59  -62  2018
• Challenges to mycotoxin contamination problems

  SAKUDA Shohei  アグリバイオ  2-  6  -7  2018
• 食品添加物を用いたアフラトキシン汚染防除

  作田庄平; 古川智宏; 飯村九林; 山本利義  Bio Industry  34-  (5)  1‐7  2017/05
• dioctatinによるClpプロテアーゼ機能異常を介したアフラトキシン生産阻害機構

  古川智宏; 片山秀和; 市川琢万; 飯村九林; 山本利義; 根岸瑠美; 鈴木道生; 作田庄平  日本農芸化学会大会講演要旨集(Web)  2017-  ROMBUNNO.3C14p05 (WEB ONLY)  2017/03
• Functional analyses of organic network in the calcite crystal of the prismatic layer of Pinctada fucata

  SUZUKI Michio; KINTSU Hiroyuki; OKUMURA Taiga; NEGISHI Lumi; IFUKU Shinsuke; KOGURE Toshihiro; SAKUDA Shohei  日本水産学会大会講演要旨集  2017 (CD-ROM)-  2017
• アコヤガイ稜柱層カルサイト結晶形成に関与するキチナーゼの働き

  近都浩之; 奥村大河; 根岸瑠美; 小暮敏博; 作田庄平; 鈴木道生  日本農芸化学会大会講演要旨集(Web)  2017-  2017
• A role of the chitinolytic enzymes in calcite crystals of the prismatic layer in Pinctada fucata.

  近都浩之; 奥村大河; 根岸瑠美; 伊福伸介; 小暮敏博; 作田庄平; 鈴木道生  キチン・キトサン研究  23-  (2)  2017
• アコヤガイ(Pinctada fucata)の真珠層石灰化に関与するカルシウムイオン応答タンパク質の同定と機能解析

  松浦晃宙; 吉村航; 渥美貴史; 土橋靖史; 竹内猛; 佐藤矩行; 根岸瑠美; 作田庄平; 井村祐己; 吉村悦郎; 鈴木道生  日本農芸化学会大会講演要旨集(Web)  2017-  2017
• Impression of the 1^st China Mycotoxin Conference 2016

  Sakuda Shohei  JSM Mycotoxins  67-  (1)  43  -44  2017
• Aspergillus属のアフラトキシン生産を阻害するdioctatinの作用機構に関する研究

  古川智宏; 片山秀和; 市川琢万; 木村太一; 飯村九林; 山本利義; 根岸瑠美; 鈴木道生; 作田庄平  日本農芸化学会大会講演要旨集(Web)  2016-  2B061 (WEB ONLY)  2016/03
• Relation between the organic network and the crystal defects in the calcite of the prismatic layer of Pinctada fucata

  KINTSU Hiroyuki; OKUMURA Taiga; NEGISHI Lumi; KOGURE Toshihiro; SAKUDA Shohei; SUZUKI Michio  日本地球惑星科学連合大会予稿集(Web)  2016-  2016
• アコヤガイ貝殻稜柱層の炭酸カルシウム結晶形成を制御する有機基質に関する研究

  近都浩之; 奥村大河; 根岸瑠美; 小暮敏博; 作田庄平; 鈴木道生  日本農芸化学会大会講演要旨集(Web)  2016-  2016
• 3-1-3 脱窒細菌Azoarcus属KH32C株接種による窒素無施肥水田土壌でのイネ生育促進（3-1 土壌生物の生態と機能，2016年度佐賀大会）

  西澤 智康; 水澤 舞花; 塩津 文隆; 作田 庄平; 藤原 徹; 太田 寬行; 妹尾 啓史  日本土壌肥料学会講演要旨集  62-  (0)  24  -24  2016
• 植物由来食品因子エリオジクチオールによるマウス制御性T細胞誘導機能の解析

  松本優樹; 松田幸; 古川智宏; 鈴木道生; 作田庄平; 清水誠; 戸塚護  日本農芸化学会大会講演要旨集(Web)  2015-  3G41A09 (WEB ONLY)  2015/03
• precocene IIによるROS産生を介したトリコテセン生産の阻害機構

  古川智宏; 鈴木道生; 作田庄平  日本農芸化学会大会講演要旨集(Web)  2015-  3D12A11 (WEB ONLY)  2015/03
• アフラトキシン生産阻害物質cyclo(L‐Ala‐L‐Pro)の作用機序の解明

  飯村九林; 古川智宏; 山本利義; 作田庄平  日本農芸化学会大会講演要旨集(Web)  2015-  3D12P07 (WEB ONLY)  2015/03
• アフラトキシン,トリコテセンの代謝制御におけるミトコンドリアの機能

  作田庄平; 古川智宏; 山本利義  日本農芸化学会大会講演要旨集(Web)  2015-  4SY06-4 (WEB ONLY)  2015/03
• アフラトキシン,トリコテセン生産阻害物質の作用機構

  作田庄平; 古川智宏; 飯村九林; 山本利義  日本生化学会大会(Web)  88th-  3W27-2 (WEB ONLY)  2015
• Fusarium graminearumのトリコテセン生産を阻害するprecocene IIの標的タンパク質の同定

  古川智宏; 坂本直子; 露木利枝; 鈴木道生; 長澤寛道; 作田庄平  日本農芸化学会大会講演要旨集(Web)  2014-  2A05P04 (WEB ONLY)  2014/03
• Fusarium graminearumのトリコテセン生産を阻害するprecocene IIの標的タンパク質に関する研究

  古川智宏; 坂本直子; 露木利枝; 長澤寛道; 作田庄平  日本農芸化学会大会講演要旨集(Web)  2013-  3C21A09 (WEB ONLY)  2013/03
• 抗喘息作用物質アロサミジン類の標的分子の探索

  桑田一平; 瀬口武史; 村岡聖子; 高城景子; 遠藤博寿; 井上博雅; 長澤寛道; 作田庄平  日本農芸化学会大会講演要旨集(Web)  2013-  2013
• OK-005 脱窒細菌Azoarcus属KH32C株の植物生育促進効果への莢膜多糖(CPS)の関与(共生・相互作用,口頭発表)

  西澤 智康; 箱山 雅生; 浦口 晋平; 作田 庄平; 藤原 徹; 磯部 一夫; 大塚 重人; 妹尾 啓史  日本微生物生態学会講演要旨集  (29)  95  -95  2013
• 3-1-13 水田土壌脱窒細菌Azoarcus KH32C株の接種による低窒素条件下での植物の生育促進(3-1 土壌生物の生態と機能,2013年度名古屋大会)

  西澤 智康; 箱山 雅生; 浦口 晋平; 角田 洋子; 磯部 一夫; 大塚 重人; 作田 庄平; 藤原 徹; 妹尾 啓史  日本土壌肥料学会講演要旨集  59-  (0)  38  -38  2013
• Prevention of aflatoxin contamination by biocontrol

  SAKUDA Shohei  JSM Mycotoxins  63-  (2)  217  -224  2013
• Analysis of interactions of allosamidins with chitinase/chitinase-like proteins

  KUWATA Ippei; MURAOKA Seiko; ENDO Hirotoshi; INOUE Hiromasa; NAGASAWA Hiromichi; SAKUDA Shohei  キチン・キトサン研究 = Chitin and chitosan research  18-  (2)  2012/07
• Mouse chitinases and chitinase-like proteins and allosamidins

  MURAOKA Seiko; NODA Naotaka; INOUE Hiromasa; KIKUCHI Naoya; NAGASAWA Hiromichi; SAKUDA Shohei  キチン・キトサン研究 = Chitin and chitosan research  17-  (1)  70  -73  2011/04
• 天然物由来のアフラトキシンおよびデオキシニバレノール生産阻害物質

  作田 庄平  Journal of pesticide science  36-  (1)  115  -118  2011/02
• 第24回キチン・キトサンシンポジウムを終えて

  作田 庄平  キチン・キトサン研究 = Chitin and chitosan research  16-  (3)  255  -257  2010/10
• Mycotoxin production inhibitors from natural products

  SAKUDA Shohei  JSM Mycotoxins  60-  (2)  79  -86  2010/07
• 天然物由来のマイコトキシン生産阻害物質

  作田 庄平  マイコトキシン  60-  (2)  79  -86  2010/07
• Mouse chitinases and chitinase-like proteins and allosamidins

  MURAOKA Seiko; NODA Naotaka; INOUE Hiromasa; KIKUCHI Naoya; NAGASAWA Hiromichi; SAKUDA Shohei  Chitin and chitosan research  16-  (2)  201  -201  2010/06
• 3S-4 Aflatoxin and deoxynivalenol production inhibitors from natural products

  Sakuda Shohei  講演要旨集  (35)  40  -40  2010/04
• Toxins of microorganisms

  Shohei Sakuda; Makoto Kimura  Comprehensive Natural Products II: Chemistry and Biology  4-  (Chemical Ecology)  411  -455  2010/03  [Refereed]
  
• Analysis of Molecular Mechanisms of Chitinase-production Promoting and Anti-asthmatic Activities of Allosamidin

  Suzuki Shigeo; Sato Yosuke; Nakanishi Eiyu; Muraoka Seiko; Matsumoto Takafumi; Inoue Hiromasa; Onishi Yasuo; Nagasawa Hiromichi; Sakuda Shohei  Symposium on the Chemistry of Natural Products, symposium papers  52-  (0)  49  -54  2010
• デオキシニバレノール生産阻害物質の探索と作用機構の解析

  露木利枝; 矢口篤; 吉成知也; 高橋治男; 中島隆; 小西良子; 長澤寛道; 作田庄平  日本農芸化学会大会講演要旨集  2009-  26  2009/03
• 9B01 Precocenes as specific inhibitors of deoxynivalenol production by Fusarium graminearum

  Tsuyuki Rie; Yaguchi Atsushi; Yoshinari Tomoya; Takahashi Haruo; Nakajima Takashi; Nagasawa Hiromichi; Sakuda Shohei  講演要旨集  (34)  86  -86  2009/02
• Chitinase Inhibitor Modulates Prostanoid Synthesis in Th2 Inflammation

  H. Inoue; T. Matsumoto; S. Fukuyama; T. Nakano; N. Noda; A. Moriwaki; K. Kan-o; K. Matsumoto; S. Sakuda; Y. Nakanishi  AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE  179-  2009
• Mycotoxin production inhibitors from essential oils

  YOSHINARI Tomoya; SAKUDA Shohei  Bioscience & industry  66-  (11)  621  -623  2008/11
• Various biological activities of allosamidin

  SAKUDA Shohei  キチン・キトサン研究 = Chitin and chitosan research  14-  (2)  110  -111  2008/07
• Effect of chitinase inhibitor allosamidin on the stress responses in plants

  TAMOI Masahiro; SAKUDA Shohei; FUKAMIZO Tamo  キチン・キトサン研究 = Chitin and chitosan research  14-  (2)  233  -233  2008/07
• 日本農芸化学会

  石神 健; 作田 庄平; 伏信 進矢; 永田 宏次; 野尻 秀昭  バイオサイエンスとインダストリー = Bioscience & industry  66-  (6)  303  -307  2008/06
• デオキシニバレノール生産阻害物質の探索 その2

  矢口篤; 吉成知也; 高橋治男; 中島隆; 小西良子; 長澤寛道; 作田庄平  日本農芸化学会大会講演要旨集  2008-  163  2008/03
• 穀類中のカビ毒デトックス法の探索と安全性評価

  小西良子; 西島基弘; 穐山浩; 作田庄平  飯島記念食品科学振興財団年報  2006-  2008
• Allosamidin Acts as a Signal Molecule for Promotion of Chitinase Production

  SUZUKI Shigeo; SAKUDA Shohei  KAGAKU TO SEIBUTSU  45-  (12)  843  -850  2007/12
• Anti-asthma activity of allosamidins

  SATO Yosuke; SUZUKI Shigeo; MATSUMOTO Takafumi; INOUE Hiromasa; NAGASAWA Hiromichi; SAKUDA Shohei  キチン・キトサン研究 = Chitin and chitosan research  13-  (2)  96  -97  2007/08
• Mechanism and generality of allosamidin's action on chitinase production of Streptomyces

  SUZUKI Shigeo; TAGAWA Naofumi; KIKUCHI Naoya; YOSHINARI Tomoya; MIYAMOTO Katsushiro; TSUJIBO Hiroshi; WATANABE Takeshi; OHNISHI Yasuo; HORINOCHI Sueharu; NAGASAWA Hiromichi; SAKUDA Shohei  キチン・キトサン研究 = Chitin and chitosan research  13-  (2)  152  -153  2007/08
• Enzymatic properties of family GH-18 chitinases from Cycas revolute and Pteris ryukyuensis

  FUJIWARA M; YAMAUCHI Y; HAYASHI H; ONAGA S; TAIRA T; SAKUDA S; FUKAMIZO T  キチン・キトサン研究 = Chitin and chitosan research  13-  (2)  196  -196  2007/08
• デオキシニバレノール生産阻害物質の探索

  矢口篤; 作田庄平; 高橋治男; 中島隆; 小西良子; 長澤寛道  日本農芸化学会大会講演要旨集  2007-  105  2007/03
• カビ毒産生機構とその制御 (科学は食のリスクをどこまで減らせるか--食の安全科学) -- (真菌(カビ毒))

  作田 庄平  生物の科学「遺伝」 別冊  (19)  172  -178  2006/10
• Analysys of the Mode of Action of Allosamidin as a Signal Molecule

  SUZUKI S; OHNISHI Y; HORINOUCHI S; NAGASAWA H; SAKUDA S  キチン・キトサン研究 = Chitin and chitosan research  12-  (2)  146  -147  2006/07
• Inhibitory Activity of Allosamidin on Mouse Acidic Chitinase

  SATO Y; S. SHIGEO; MATSUMOTO T; INOUE H; NAGASAWA H; SAKUDA S  キチン・キトサン研究 = Chitin and chitosan research  12-  (2)  216  -216  2006/07
• カビ毒産生機構とその制御

  作田庄平  遺伝別冊  19-  172  -178  2006
• Studies on the molecular mechanism of the induction of chitinase production by allosamidin in an allosamidin-producing Streptomyces

  SUZUKI Shigeo; KAWACHI Ryu; OHNISHI Yasuo; HORINOUCHI Sueharu; SAKUDA Shohei; NAGASAWA Hiromichi  キチン・キトサン研究 = Chitin and chitosan research  11-  (2)  124  -125  2005/07
• 技術座談会 最新微生物研究の動向 難培養微生物からメタゲノム解析へ

  作田 庄平; 竹中 昭雄; 中川 智  Techno innovation  15-  (1)  6  -18  2005
• Protection of Fusarium mycotoxin contamination with specific inhibitors of mycotoxin production

  作田 庄平; 高橋 治男; 中島 隆  年報  2005-  246  -250  2005
• Inhibitors of Secondary Metabolite Production of Fungi : Aflastatin, an Inhibitor of Aflatoxin Production

  SAKUDA Shohei; KONDO Tatsuhiko  化学と生物  42-  (7)  442  -448  2004/07
• Studies on the molecular mechanism of the induction of chitinase production by allosamidin in an allosamidin-producing Streptomyces

  SUZUKI Shigeo; KAWACHI Ryu; OHNISHI Yasuo; HORINOUCHI Sueharu; SAKUDA Shohei; NAGASAWA Hiromichi  キチン・キトサン研究 = Chitin and chitosan research  10-  (2)  110  -111  2004/07
• 2004 Annual Meeting of Japan Society for Bioscience, Biotechnology, and Agrochemistry

  ARAI Hiroyuki; FUKUDA Ryouichi; SATSU Hideo; KIYOTA Hiromasa; SAKUDA Shouhei; KIMURA Yukitaka; SUMITA Toru  Bioscience & industry  62-  (6)  393  -397  2004/06
• 腸管上皮細胞Caco-2におけるP糖タンパク質活性に与えるニガウリ抽出物の効果

  小西知子; 薩秀夫; 初谷泰夫; 永田晋治; 作田庄平; 長沢寛道; 相沢宏一; 稲熊隆博; 清水誠  日本農芸化学会大会講演要旨集  2004-  2004
• Inhibitors of Secondary Metabolite Production of Fungi-Aflastatin, an Inhibitor of Aflatoxin Production:Aflastatin, an Inhibitor of Aflatoxin Production

  SAKUDA Shohei; KONDO Tatsuhiko  KAGAKU TO SEIBUTSU  42-  (7)  442  -448  2004
• 麦類赤かび病菌のマイコトキシン生産を特異的に抑制する薬剤を用いたマイコトキシン汚染防除法の開発

  作田 庄平; 高橋 治男; 中島 隆  年報  2004-  291  -295  2004
• Allosamidin and its Related Chitinases

  SAKUDA Shohei; NAKANISHI Eiyu; NAGASAWA Hiromichi  キチン・キトサン研究 = Chitin and chitosan research  9-  (2)  84  -85  2003/06
• 有限と無限

  作田 庄平  バイオサイエンスとインダストリー = Bioscience & industry  61-  (4)  37  -37  2003/04
• eDNAに含まれる二次代謝産物生合成遺伝子の利用

  作田庄平; 中山二郎; 河内隆; 岡本晋; 松田智子; 上迫和也; 長澤寛道  日本放線菌学会大会講演要旨集  18th-  2003
• Gordonia sp. の生産する昆虫由来BM-N4細胞凝集活性を有する酸性多糖Gordonan

  近藤 竜彦; 山本 大介; 横田 明; 鈴木 昭憲; 長澤 寛道; 作田 庄平  日本農藝化學會誌 = Journal of the Agricultural Chemical Society of Japan  76-  (10)  970  -971  2002/10
• キチン・キトサン学会座談会 : キチン・キトサンにかける夢を語る

  相羽 誠一; 岡本 芳晴; 斎藤 幸恵; 坂井 和男; 作田 庄平; 滝口 泰之; 徳安 健; 長岡 功; 安藤 昭一  キチン・キトサン研究 = Chitin and chitosan research  8-  (3)  283  -298  2002/10
• 未分離微生物の二次代謝産物生合成遺伝子の利用

  作田 庄平; 中山 二郎  化学と生物  40-  (9)  600  -605  2002/09
• Studies on the Induction Mechanism of Chitinase Production by Allosamidin in an Allosamidin-producing Streptomyces (II)

  NAKANISHI Eiyu; SAKUDA Shohei; NAGASAWA Hiromichi  キチン・キトサン研究 = Chitin and chitosan research  8-  (2)  156  -157  2002/07
• Studys on allosamidin and aflastatin, novel inhibitors of important metabolic patyways, from microorganisms.

  SAKUDA Shohei  The Japanese journal of antibiotics  55-  (3)  311  -318  2002/06
• Studies on the mode of action of aflastain A, an inhibitor of aflatoxin production

  SAKUDA Shohei  JSM Mycotoxins  52-  (2)  153  -159  2002
• Chemical synthesis and biological activity of the gelatinase biosynthesis-activating pheromone of Enterococcus faecalis and its analogs

  J Nakayama; Y Cao; T Horii; S Sakuda; H Nagasawa  BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY  65-  (10)  2322  -2325  2001/10
• Studies on the Induction Mechanism of Chitinase Production by Allosamidin in an Allosamidin-producing Streptomyces

  NAKANISHI Eiyu; SAKUDA Shohei; NAGASAWA Hiromichi  キチン・キトサン研究 = Chitin and chitosan research  7-  (2)  176  -177  2001/07
• Biosynthetic studies on the cyclopentane ring formation of allosamizoline, an aminocyclitol component of the chitinase inhibitor allosamidin

  S Sakuda; Y Sugiyama; ZY Zhou; H Takao; H Ikeda; K Kakinuma; Y Yamada; H Nagasawa  JOURNAL OF ORGANIC CHEMISTRY  66-  (10)  3356  -3361  2001/05
• Allosamidin, a chitinase inhibitor produced by Streptomyces, acts as an inducer of chitinase production in its producing strain

  E Nakanishi; S Okamoto; H Matsuura; H Nagasawa; S Sakuda  PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES  77-  (5)  79  -82  2001/05
• 難培養性土壌細菌群が有するポリケチド生合成遺伝子の多様性および新規性の解析

  中山二郎; 松田智子; 上迫和也; 河内隆; 岡本晋; 作田庄平; 長沢寛道  日本農芸化学会誌  75-  2001
• 腸球菌のプロテアーゼ生産におけるクオーラムセンシングを制御するgelatinase biosynthesis activating pheromone(GBAP)

  中山二郎; 曹庸; 堀井孝昭; 作田庄平; 長沢寛道  日本農芸化学会誌  75-  2001
• 難培養性微生物を含む土壌由来,新規II型ポリケタイド生合成酵素遺伝子の探索

  河内隆; 上迫和也; 岡本晋; 中山二郎; 作田庄平; 長沢寛道  日本農芸化学会誌  75-  2001
• Blasticidin A derivatives with highly specific inhibitory activity toward aflatoxin production in Aspergillus parasiticus

  S Sakuda; H Ikeda; T Nakamura; R Kawachi; T Kondo; M Ono; M Sakurada; H Inagaki; R Ito; H Nagasawa  JOURNAL OF ANTIBIOTICS  53-  (12)  1378  -1384  2000/12
• Blasticidin A as an inhibitor of aflatoxin production by Aspergillus parasiticus

  S Sakuda; M Ono; H Ikeda; T Nakamura; Y Inagaki; R Kawachi; J Nakayama; A Suzuki; A Isogai; H Nagasawa  JOURNAL OF ANTIBIOTICS  53-  (11)  1265  -1271  2000/11
• Gordonan, an acidic polysaccharide with cell aggregation-inducing activity in insect BM-N4 cells, produced by Gordonia sp.

  T Kondo; D Yamamoto; A Yokota; A Suzuki; H Nagasawa; S Sakuda  BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY  64-  (11)  2388  -2394  2000/11
• Absolute configuration of aflastatin A, a specific inhibitor of aflatoxin production by Aspergillus parasiticus

  H Ikeda; N Matsumori; M Ono; A Suzuki; A Isogai; H Nagasawa; S Sakuda  JOURNAL OF ORGANIC CHEMISTRY  65-  (2)  438  -444  2000/01
• Family 19 chitinases of Streptomyces species: characterization and distribution

  T Watanabe; R Kanai; T Kawase; T Tanabe; M Mitsutomi; S Sakuda; K Miyashita  MICROBIOLOGY-UK  145-  3353  -3363  1999/12
• Studies on Chitinases Produced by Allosamidin-producing Streptomyces

  MATSUURA H; OKAMOTO S; SAKUDA S; ANAMNART S; WANG Q; ZHOU Z.-Y; NIHIRA T; YAMADA Y; KUZUYAMA T; SETO H; SUZUKI A; NAGASAWA H  キチン・キトサン研究 = Chitin and chitosan research  5-  (2)  228  -229  1999/07
• Aflastatin A, a new metabolite from Streptomyces that inhibits the biosynthesis of aflatoxin

  ONO Makoto; SAKUDA Shouhei  JSM Mycotoxins  48-  1  -7  1999/01
• 42 Absolute Configuration of Aflastatin A, a Specific Inhibitor of Aflatoxin Production, and Structures and Activity of Its Related Compounds

  Ikeda Hiroyuki; Matsumori Nobuaki; Inagaki Yasuhito; Suzuki Akinori; Nakayama Jiro; Nagasawa Hiromichi; Sakuda Shohei; Ono Makoto; Isogai Akira  Symposium on the Chemistry of Natural Products, symposium papers  41-  (0)  247  -252  1999
• Structures and biosynthesis of Aflastatins: Novel inhibitors of aflatoxin production by Aspergillus parasiticus

  M Ono; S Sakuda; H Ikeda; K Furihata; J Nakayama; A Suzuki; A Isogai  JOURNAL OF ANTIBIOTICS  51-  (11)  1019  -1028  1998/11
• Preparation of biotinylated allosamidins with strong chitinase inhibitory activities

  S Sakuda; M Sakurada  BIOORGANIC & MEDICINAL CHEMISTRY LETTERS  8-  (21)  2987  -2990  1998/11
• Morphological changes in insect BM-N4 cells induced by nocardamine

  K Matsubara; S Sakuda; T Kondo; M Tanaka; T Nishimura; A Suzuki  BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY  62-  (10)  2049  -2051  1998/10
• Enterococcus faecal is の性フェロモン受容体タンパク質TraAの機能解析

  堀井 孝昭; 中山 二郎; 作田 庄平; 長澤 寛道  日本乳酸菌学会誌 = Journal of Japan Society for Lactic Acid Bacteria  9-  (1)  18  -18  1998/09
• Preparation and Application of Biotinylated Allosamidins

  SAKUDA S; SAKURADA M  キチン・キトサン研究 = Chitin and chitosan research  4-  (2)  216  -217  1998/05
• Regulators of secondary metabolite production of fungi

  S Sakuda  NIPPON NOGEIKAGAKU KAISHI-JOURNAL OF THE JAPAN SOCIETY FOR BIOSCIENCE BIOTECHNOLOGY AND AGROCHEMISTRY  72-  (1)  72  -74  1998/01
• Studies on regulators of secondary metabolite production of fung ;

  71-  (1)  72  -74  1998
• Structure of blasticidin A

  S Sakuda; M Ono; H Ikeda; Y Inagaki; J Nakayama; A Suzuki; A Isogai  TETRAHEDRON LETTERS  38-  (42)  7399  -7402  1997/10
• Aflastatin A, a novel inhibitor of aflatoxin production of Aspergillus parasiticus, from Streptomyces.

  A Isogai; S Sakuda; M Ono; H Ikeda; M Sakurada; K Furihata; J Nakayama; A Suzuki  ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY  214-  90  -AGRO  1997/09
• 非メバロン酸経路によるイソプレノイドの生合成 (1997年の化学-7-)

  作田 庄平  化学  52-  (7)  64  -65  1997/07
• Mycothiol, 1-O-(2'-[N-acetyl-L-cysteinyl]amido-2'-deoxy-alpha-D-glucopyranosyl)-D-myo-inositol, is the factor of NAD/factor-dependent formaldehyde dehydrogenase

  M MissetSmits; PW vanOphem; S Sakuda; JA Duine  FEBS LETTERS  409-  (2)  221  -222  1997/06
• A novel inhibitor of aflatoxin production

  SAKUDA Shohei; ONO Makoto  バイオサイエンスとインダストリー = Bioscience & industry  55-  (4)  35  -36  1997/04
• Aflastatin A, a novel inhibitor of aflatoxin production by aflatoxigenic fungi

  M Ono; S Sakuda; A Suzuki; A Isogai  JOURNAL OF ANTIBIOTICS  50-  (2)  111  -118  1997/02
• 40 STUDIES ON AFLASTATIN, A NOVEL INHIBITOR OF AFLATOXIN PRODUCTION

  Sakuda S; Ikeda H; Sakurada M; Furihata K; Nakayama J; Suzuki A; Ono M; Isogai A  Symposium on the Chemistry of Natural Products, symposium papers  39-  (0)  235  -240  1997
• Involvement of Afs A in A-factor biosynthesis as a Key enzyme. (共著)

  NORIKO ANDO; NOBUAKI MATSUMORI; SHOHEI SAKUDA; TERUHIKO BEPPU; SUEHARU HORINOUCHI  Journol of Antibiotics  50-  (10)  847  -852  1997
• Novel linear polyene antibiotics: Linearmycins

  S Sakuda; U GuceBigol; M Itoh; T Nishimura; Y Yamada  JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1  (18)  2315  -2319  1996/09
• Mechanism of the cyclopentane ring formation of allosamizoline, an aminocyclitol derivative of the chitinase inhibitor allosamidin

  S Sakuda; ZY Zhou; H Takao; Y Yamada  TETRAHEDRON LETTERS  37-  (32)  5711  -5714  1996/08
• Aflastatin A, a novel inhibitor of aflatoxin production of Aspergillus parasiticus, from Streptomyces

  S Sakuda; M Ono; K Furihata; J Nakayama; A Suzuki; A Isogai  JOURNAL OF THE AMERICAN CHEMICAL SOCIETY  118-  (33)  7855  -7856  1996/08
• 新規直鎖状ポリエン抗生物質linearmycinの単離、構造及び生合成 : 有機化学・天然物化学

  作田 庄平; Guce-Bigol U; 伊藤 睦弘; 西村 孝史; 山田 靖宙  日本農藝化學會誌  69-  (0)  2  -2  1995/07
• LINEARMYCIN-A, A NOVEL LINEAR POLYENE ANTIBIOTIC

  S SAKUDA; U GUCEBIGOL; M ITOH; T NISHIMURA; Y YAMADA  TETRAHEDRON LETTERS  36-  (16)  2777  -2780  1995/04
• STUDIES ON CHITINASE INHIBITORS

  S SAKUDA  NIPPON NOGEIKAGAKU KAISHI-JOURNAL OF THE JAPAN SOCIETY FOR BIOSCIENCE BIOTECHNOLOGY AND AGROCHEMISTRY  69-  (2)  147  -153  1995/02
• P-69 BIOSYNTHETIC STUDIES ON THE CHITINASE INHIBITOR, ALLOSAMIDIN

  SAKUDA Shohei; ZHOU Ze-Yang; TAKAO Hiroaki; YAMADA Yasuhiro  Symposium on the Chemistry of Natural Products, symposium papers  37-  (0)  678  -683  1995
• ISOLATION OF TAUTOMYCETIN AS A REGULATOR OF SECONDARY METABOLITE PRODUCTION FOR PENICILLIUM-URTICAE

  S SAKUDA; K MIKI; S KITAOKA; M REUGJITCHACHAWALY; Y YAMADA  BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY  59-  (1)  133  -134  1995/01
• STRUCTURE OF PATULODIN, A NEW AZAPHILONE EPOXIDE, PRODUCED BY PENICILLIUM-URTICAE

  S SAKUDA; Y OTSUBO; Y YAMADA  JOURNAL OF ANTIBIOTICS  48-  (1)  85  -86  1995/01
• PREPARATION OF A DEMETHYLALLOSAMIDIN ISOMER HAVING AN N,N'-DIACETYLCHITOBIOSYL MOIETY AND ITS POTENT INHIBITION AGAINST YEAST CHITINASE

  S TAKAHASHI; H TERAYAMA; H KUZUHARA; S SAKUDA; Y YAMADA  BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY  58-  (12)  2301  -2302  1994/12
• STRUCTURE OF A NOVEL DISULFIDE OF 2-(N-ACETYLCYSTEINYL)AMIDO-2-DEOXY-ALPHA-D-GLUCOPYRANOSYL-MYO-INOSITOL PRODUCED BY STREPTOMYCES SP

  S SAKUDA; ZY ZHOU; Y YAMADA  BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY  58-  (7)  1347  -1348  1994/07
• STRUCTURE OF A NOVEL DISULFIDE OF 2-(N-ACETYLCYSTEINYL)AMIDO-2-DEOXY-ALPHA-D-GLUCOPYRANOSYL-MYO-INOSITOL PRODUCED BY STREPTOMYCES SP

  S SAKUDA; ZY ZHOU; Y YAMADA  BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY  58-  (7)  1347  -1348  1994/07
• EFFECT OF DEMETHYLALLOSAMIDIN, A CHITINASE INHIBITOR, ON MORPHOLOGY OF FUNGUS GEOTRICHUM-CANDIDUM

  S YAMANAKA; N TSUYOSHI; R KIKUCHI; S TAKAYAMA; S SAKUDA; Y YAMADA  JOURNAL OF GENERAL AND APPLIED MICROBIOLOGY  40-  (2)  171  -174  1994/04
• Enzymatic resolution of 2-acyl-3-hydroxymethyl-4-butanolide and determination of the absolute configuration of IM-2

  Mizuno K; Sakuda S; Nihira T; Yamada Y  日本生物工学会大会講演要旨集  6-  211  -211  1994
• Enzymatic resolution of 2-acyl-3-hydroxymethyl-4-butanolide and preparation of optically active IM-2, the autoregulator from Streptomyces sp. FRI-5

  Kimihiro Mizuno; Shohei Sakuda; Takuya Nihira; Yasuhiro Yamada  Tetrahedron  50-  (37)  10849  -10858  1994
• BIOSYNTHETIC-STUDIES OF ALLOSAMIDIN .2. ISOLATION OF DIDEMETHYLALLOSAMIDIN, AND CONVERSION EXPERIMENTS OF C-14-LABELED DEMETHYLALLOSAMIDIN, DIDEMETHYLALLOSAMIDIN AND THEIR RELATED-COMPOUNDS

  ZY ZHOU; S SAKUDA; M KINOSHITA; Y YAMADA  JOURNAL OF ANTIBIOTICS  46-  (10)  1582  -1588  1993/10
• PREPARATION OF N-MONOALKYL AND O-ACYL DERIVATIVES OF ALLOSAMIDIN, AND THEIR CHITINASE INHIBITORY ACTIVITIES

  M KINOSHITA; S SAKUDA; Y YAMADA  BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY  57-  (10)  1699  -1703  1993/10
• キチナ-ゼ阻害物質アロサミジン類の化学

  作田 庄平  バイオサイエンスとインダストリ-  51-  (6)  p470  -475  1993/06
• PURIFICATION OF ALLOSAMIDIN-SENSITIVE AND ALLOSAMIDIN-INSENSITIVE CHITINASES PRODUCED BY ALLOSAMIDIN-PRODUCING STREPTOMYCES

  QQ WANG; ZY ZHOU; SH SAKUDA; Y YAMADA  BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY  57-  (3)  467  -470  1993/03
• Biosynthetic Studies on Virginiae Butanolide A, Part 2.

  Sakuda Shohei; Tanaka Sumiko; Mizuno Kimihiro; Sukcharoen Oratai; Nihira Takuya; Yamada Yasuhiro  日本生物工学会大会講演要旨集  5-  214  -214  1993
• Synthesis of a new allosamidin analog, n,n′-diacetyl-β-chitobiosyl allosamizoline, and its inhibitory activity against some chitinases

  Hiroyuki Terayama; Hiroyoshi Kuzuhara; Shunya Takahashi; Shohei Sakuda; Yasuhiro Yamada  Bioscience, Biotechnology and Biochemistry  57-  (12)  2067  -2069  1993
• Biosynthetic studies on virginiae butanolide A, abutyrolactone autoregulator from streptomyces. Part2. (共著)

  Journal of Chemical Society Parkin Transaction I.  2309-2315-  1993
• Chemistory and Biochemistry of the chitinase inhibitors, allosamidins. (共著)

  Actinomycetologica  7-  (2)  50  -57  1993
• Chemistry of the chitinase inhibitors allosamidins

  51-  (6)  18  -23  1993
• BIOSYNTHETIC-STUDIES ON THE CHITINASE INHIBITOR, ALLOSAMIDIN - ORIGIN OF THE CARBON AND NITROGEN-ATOMS

  ZY ZHOU; S SAKUDA; Y YAMADA  JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1  (13)  1649  -1652  1992/07
• Streptomyces属のブタノライド型自己調節因子の合成--経路の大筋をほぼ解明.他の因子の場合にも共通か(今日の話題)

  作田 庄平; 山田 靖宙  化学と生物  30-  (3)  p145  -147  1992/03
• Biosynthesis and receptor protein of butyrolactone autoregulator of Streptomyces virginiae

  Yasuhiro Yamada; Takuya Nihira; Shohei Sakuda  Actiomycetal  6-  (1)  1  -8  1992
• IM-2, A BUTYROLACTONE AUTOREGULATOR, INDUCES PRODUCTION OF SEVERAL NUCLEOSIDE ANTIBIOTICS IN STREPTOMYCES SP FRI-5

  K HASHIMOTO; T NIHIRA; S SAKUDA; Y YAMADA  JOURNAL OF FERMENTATION AND BIOENGINEERING  73-  (6)  449  -455  1992
• NEW INDUCING FACTORS FOR VIRGINIAMYCIN PRODUCTION FROM STREPTOMYCES-ANTIBIOTICUS

  W LI; T NIHIRA; S SAKUDA; T NISHIDA; Y YAMADA  JOURNAL OF FERMENTATION AND BIOENGINEERING  74-  (4)  214  -217  1992
• BIOSYNTHESIS OF VIRGINIAE BUTANOLIDE-A, A BUTYROLACTONE AUTOREGULATOR FROM STREPTOMYCES

  S SAKUDA; A HIGASHI; S TANAKA; T NIHIRA; Y YAMADA  JOURNAL OF THE AMERICAN CHEMICAL SOCIETY  114-  (2)  663  -668  1992/01
• ISOLATION AND CHARACTERIZATION OF NEW ALLOSAMIDINS

  Y NISHIMOTO; S SAKUDA; S TAKAYAMA; Y YAMADA  JOURNAL OF ANTIBIOTICS  44-  (7)  716  -722  1991/07
• STEREOCHEMISTRY OF BUTYROLACTONE AUTOREGULATORS FROM STREPTOMYCES

  S SAKUDA; Y YAMADA  TETRAHEDRON LETTERS  32-  (15)  1817  -1820  1991/04
• EFFECTS OF DEMETHYLALLOSAMIDIN, A POTENT YEAST CHITINASE INHIBITOR, ON THE CELL-DIVISION OF YEAST

  S SAKUDA; Y NISHIMOTO; M OHI; M WATANABE; S TAKAYAMA; A ISOGAI; Y YAMADA  AGRICULTURAL AND BIOLOGICAL CHEMISTRY  54-  (5)  1333  -1335  1990/05
• Allosamidins, novel chitinase inhibitors

  Sakuda S; Nishimoto Y; Ohi M; Isogai A; Suzuki A; Takayama S; Yamada Y  日本醗酵工学会大会講演要旨集  2-  114  -114  1990
• 4 Biosynthesis of Virginiae Butanolide A

  Sakuda Shohei; Higashi Ayako; Tanaka Sumiko; Nihira Takuya; Yamada Yasuhiro  Symposium on the Chemistry of Natural Products, symposium papers  32-  (0)  25  -32  1990
• 微生物の生産する昆虫成育制御物質

  作田 庄平  遺伝  44-  (1)  p71  -76  1990/01
• STRUCTURE OF DEMETHYLALLOSAMIDIN AS AN INSECT CHITINASE INHIBITOR

  A ISOGAI; M SATO; S SAKUDA; J NAKAYAMA; A SUZUKI  AGRICULTURAL AND BIOLOGICAL CHEMISTRY  53-  (10)  2825  -2826  1989/10
• Effect of demethylallosamidin on the growth of yeast

  Sakuda S; Nishimoto Y; Oi M; Watanabe M; Takayama S; Isogai A; Yamada Y  日本醗酵工学会大会講演要旨集  0-  93  -93  1989
• Purification and Structure Elucidation of the Signal Molecule for Blue Pigment Production by Streptomyces sp. FRI-5.

  Sato Katsuhiko; Nihira Takuya; Sakuda Shohei; Yanagimoto Masakatsu; Yamada Yasuhiro  日本醗酵工学会大会講演要旨集  0-  97  -97  1989
• Biosynthesis of virginiae butanolide A

  Higashi Ayako; Sakuda Shohei; Nihira Takuya; Yamada Yasuhiro  日本醗酵工学会大会講演要旨集  0-  98  -98  1989
• 生物化学工学若手研究者のつどい

  作田 庄平; 岡田 尚輔; 島 康文; 高木 昌宏; 藤山 和仁  醗酵工学会誌 : hakkokogaku kaishi  67-  (5)  475  -475  1989
• ABSOLUTE-CONFIGURATION OF ALLOSAMIZOLINE, AN AMINOCYCLITOL DERIVATIVE OF THE CHITINASE INHIBITOR ALLOSAMIDIN

  S SAKUDA; A ISOGAI; S MATSUMOTO; A SUZUKI; K KOSEKI; H KODAMA; Y YAMADA  AGRICULTURAL AND BIOLOGICAL CHEMISTRY  52-  (6)  1615  -1617  1988/06
• 昆虫のキチナーゼ阻害物質allosamidinの絶対構造(有機化学・天然物化学-生理活性物質(昆虫)-)

  作田 庄平; 磯貝 彰; 松本 正吾; 鈴木 昭憲; 古関 幸史; 児玉 久  日本農藝化學會誌  62-  (3)  566  -566  1988/03
• 「昭和63年度生物化学工学若手研究者の集い」報告

  作田 庄平; 島 康文  醗酵工学会誌 : hakkokogaku kaishi  66-  (5)  443  -444  1988
• Mechanism of salt tolerance of halophilic bacteria, Halomonas sp.

  Okuda Mitsuyoshi; Sakuda Shohei; Shinmyo Atsuhiko; Takano Mitsuo; Imai Ko  日本醗酵工学会大会講演要旨集  63-  193  -193  1988
• PC88 THE STRUCTURES OF INDUCING FACTORS FOR VIRGINIAMYCIN PRODUCTION IN Streptomyces virginiae

  Kondo Koichi; Higuchi Yutaka; Sakuda Shohei; Nihira Takuya; Yamada Yasuhiro  International Symposium on the Chemistry of Natural Products  1988-  (0)  544  -544  1988
• PD33 BIOSYNTHESIS OF MACROLIDE ANTIBIOTIC PATULOLIDES BY Penicillium urticae S11R59 : IDENTIFICATION OF THE ORIGIN OF CARBON ATOMS BY ^<13>C NMR SPECTROSCOPY

  Rodphaya Dararat; Nihira Takuya; Sakuda Shohei; Yamada Yasuhiro  International Symposium on the Chemistry of Natural Products  1988-  (0)  585  -585  1988
• STRUCTURES OF ALLOSAMIDINS, NOVEL INSECT CHITINASE INHIBITORS, PRODUCED BY ACTINOMYCETES

  S SAKUDA; A ISOGAI; T MAKITA; S MATSUMOTO; K KOSEKI; H KODAMA; A SUZUKI  AGRICULTURAL AND BIOLOGICAL CHEMISTRY  51-  (12)  3251  -3259  1987/12
• ISOLATION AND STRUCTURAL ELUCIDATION OF A NEW CYCLITOL DERIVATIVE, STREPTOL, AS A PLANT-GROWTH REGULATOR

  A ISOGAI; S SAKUDA; J NAKAYAMA; S WATANABE; A SUZUKI  AGRICULTURAL AND BIOLOGICAL CHEMISTRY  51-  (8)  2277  -2279  1987/08
• SEARCH FOR MICROBIAL INSECT GROWTH-REGULATORS .2. ALLOSAMIDIN, A NOVEL INSECT CHITINASE INHIBITOR

  S SAKUDA; A ISOGAI; S MATSUMOTO; A SUZUKI  JOURNAL OF ANTIBIOTICS  40-  (3)  296  -300  1987/03
• Isolation and Structure of New Virginiae butanolides, Inducing Factor for Staphyromycin Production

  Kondo Koichi; Higuchi Yutaka; Sakuda Shohei; Nihira Takuya; Yamada Yasuhiro  日本醗酵工学会大会講演要旨集  62-  85  -85  1987
• Structure of patulolide D, a new macrolide from Penicillium urticae mutant S11R

  Sakuda Shohei; Rodphaya Dararat; Isogai Akira; Yamada Yasuhiro  日本醗酵工学会大会講演要旨集  62-  86  -86  1987
• 9 Structures of Allosamidins, Novel Insect Chitinase Inhibitors, Produced by Microorganisms

  Sakuda Shohei; Isogai Akira; Makita Tsukasa; Matsumoto Shogo; Suzuki Akinori; Koga Daizo; Koseki Koshi; Kodama Hisashi; Noma Masana  Symposium on the Chemistry of Natural Products, symposium papers  28-  (0)  65  -72  1986
• STRUCTURES OF CYCLOCARBAMIDES-A AND CYCLOCARBAMIDES-B, NEW PLANT-GROWTH REGULATORS FROM STREPTOVERTICILLIUM-SP

  A ISOGAI; S SAKUDA; K SHINDO; S WATANABE; A SUZUKI; S FUJITA; T FURUYA  TETRAHEDRON LETTERS  27-  (10)  1161  -1164  1986
• THE STRUCTURE OF LEUCANICIDIN, A NOVEL INSECTICIDAL MACROLIDE PRODUCED BY STREPTOMYCES-HALSTEDII

  A ISOGAI; S SAKUDA; S MATSUMOTO; M OGURA; K FURIHATA; H SETO; A SUZUKI  AGRICULTURAL AND BIOLOGICAL CHEMISTRY  48-  (5)  1379  -1381  1984

Industrial Property Rights

• 特願2019-138058:サーモスポロスリックス・ハザケンシス（Thermosporothrix hazakensis）由来の抗菌活性物質  2019年/07/26
• 特願2016-66659:アフラトキシン産生阻害剤及びアフラトキシン汚染防除方法  2016年

  作田庄平, 山本利義, 飯村九林, 古川智宏, 木村太一
• 特開2014-70038:アフラトキシン産生阻害剤及びその製造方法、ノルソロリン酸産生阻害剤、ｍＲＮＡ発現抑制剤、並びに、アフラトキシン汚染防除方法  2014

  作田庄平, 長澤寛道, ウスマ ジャムナク
• 特願2013-145423:アフラトキシン産生阻害剤、及びアフラトキシン汚染防除方法  2013年

  作田庄平, ジヤン、フェブリ フルボオ, 髙城景子
• アフラトキシン生産阻害剤、及びそれを用いたアフラトキシン汚染防除方法

Awards & Honors

• 2009 日本マイコトキシン学会 学術賞
   

  受賞者: 作田 庄平
• 2001 日本抗生物質学術協議会住木・梅澤記念賞
   JPN
• 1994 農芸化学奨励賞
   JPN

Research Grants & Projects

• フザリウムによる真菌性角膜炎の重症化におけるマイコトキシンの関与の解明

  日本学術振興会：科学研究費助成事業

  Date (from‐to) : 2021/04 -2025/03 

  Author : 戸所 大輔; 作田 庄平
• Creation of next-generation pest control drugs by elucidation of the indirect defence mechanism of plants

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 2017/04 -2021/03 

  Author : Matsuda Kazuhiko
• Analysis of molecular mechanism of anti-asthmatic activity of allosamidin by focusing the function of chitinase-like proteins

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 2011/04 -2014/03 

  Author : SHOHEI Sakuda; INOUE Hiromasa
• New method for identifying target molecules of bioactive compounds

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 2010 -2012 

  Author : SAKUDA Shohei
• The study on mycotoxin detoxification and protection of animal mycotoxicoses in Thaoland.

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 2008 -2010 

  Author : KUMAGAI Susumu; KONISHI Yoshiko; SAKUDA Shohei; TAKATORI Kousuke; PRAPEUK Tangmunkhong; AMNART Poapolathep
• Development of chemical biology based on allosamidin molecule

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 2008 -2010 

  Author : SAKUDA Shohei; INOUE Hiromasa
• Regulation mechanism of biomineralization based on interaction between organic matrices and inorganic crystals

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 2005 -2009 

  Author : NAGASAWA Hiromichi; KOGURE Toshihiro; TAKAGI Yasuaki; SAKUDA Shohei
• アフラトキシンの生産菌における生理的役割に関する研究

  日本学術振興会：科学研究費助成事業

  Date (from‐to) : 2007 -2008 

  Author : 作田 庄平
• Analysis of a physiological role and anti-asthmatic activity of the chitinase inhibior allosamidin

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 2005 -2007 

  Author : SAKUDA Shohei; INOUE Hiromasa
• Modulation of Cytokine Signals and Treatment for Inflammatory Lung Diseases

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 2005 -2006 

  Author : INOUE Hiromasa; MATSUMOTO Koichiro; KUBO Masato; SAKUDA Shohei
• アフラトキシン生産阻害物質を用いたアフラトキシン生産調節機構の解析

  日本学術振興会：科学研究費助成事業

  Date (from‐to) : 2001 -2002 

  Author : 作田 庄平
• Isolation and identification of a self-growth-inhibiting substance produced by Legionella sp. and its application as an anti-Legionella drug

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 2000 -2001 

  Author : SAKUDA Shohei; KAWANO Genji
• 雲南地域の植物性抗がん剤に関する研究

  日本学術振興会：科学研究費助成事業

  Date (from‐to) : 1999 -1999 

  Author : 永井 和夫; 姚 新生; 作田 庄平; 西村 敏男; 孫 啓時; 邵 剛
• Studies of Floral Antitumor Medicines in Yunnan Province

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 1998 -1998 

  Author : NISHIMURA Toshio; SAKUDA Shohei; TSURUO Takashi; NAGAI Kazuo; CUI Cheng-bin; YAO Xin-sheng
• Search for bioactive substances acting on insect neuropeptide receptors and application of them to insect growth requlators.

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 1996 -1998 

  Author : SAKUDA Shohei; HATAKOSHI Makoto; KATAOKA Hiroshi; SUZUKI Akinori
• Studies of Floral Antitumor Medicines in Yunnan Province

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 1997 -1997 

  Author : NISHIMURA Toshio; SAKUDA Shohei; TSURUO Takashi; YAO Xin-sheng; CUI Cheng-bin; SHAO Gang
• Studies of Floral Antitumor Medicines in Yunnan Province

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 1996 -1996 

  Author : OTAKE Noboru; NISHIMURA Toshio; SAKUDA Shohei; SUZUKI Akinori; YAO Shin-Sheng; CHEN Ying-Jie
• Studies of Floral Antitumor Medicines in Yunnan Province

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 1995 -1995 

  Author : OTAKE Noboru; NISHIMURA Toshio; SAKUDA Shohei; SUZUKI Akinori; YAO Shin-Sheng; SUN Qi Shi; CHEN Ying-Jie
• Disturibution and function of autoregulator jin streptomyces species producing antibiotics

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 1992 -1993 

  Author : NIHIRA Takuya; SAKUDA Shohei; YAMADA Yasuhiro
• Biosynthesis of the chitinase inhibitor allosamidin produced by Streptomyces

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 1992 -1993 

  Author : YAMADA Yasuhiro; SAKUDA Shohei; NIHIYA Takuya
• Distribution and function of novel inducing factor for secondary metabolism

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 1990 -1991 

  Author : NIHIRA Takuya; SAKUDA Shohei; YAMADA Yasuhiro
• Screening of Virginiamycin Inducing Factors in Antibiotic-Producing Atcinomycetes

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 1988 -1990 

  Author : YAMADA Yasuhiro; SAKUDA Shohei; NIHIRA Takuya
• アフラトキシン生産阻害物質に関する研究
• 微生物の生産する生理活性物質に関する研究
• キチナーゼ阻害物質に関する研究
• Studies on inhibitors of aflatoxin production
• studies on bioactive compounds produced by microorganisms
• Studies on chitinase inhibitors

Committee Membership

• 2022 -2024   Japanese Society for Chitin and Chitosan   President
• 2016/01 -2023   Japanese Society of Mycotoxicology   President