Sakoori Kazuto

Researcher Information

Affiliation

Faculty of Pharmaceutical Sciences Assistant Professor
Graduate School of Pharmaceutical Sciences Assistant Professor

URL

https://jglobal.jst.go.jp/detail?JGLOBAL_ID=201501009743911770

J-Global ID

• 201501009743911770

Research Interests

• 包括脳ネットワーク   薬物依存   ノシセプチン   自閉症   カンナビノイド   

Research Areas

• Life sciences / Neuroscience - general

Academic & Professional Experience

• 2023/04 - Today  Teikyo UniversityAdvanced Comprehensive Research Organization
• 2020/07 - 2023/03  The University of TokyoFaculty of Medicine
• 2012 - 2020/06  The University of TokyoFaculty of Medicine
• 2009 - 2009  Tokyo University of Agriculture and Technology

Association Memberships

• 北米神経科学会   日本神経科学会   

Research Activity Information

Published Papers

• PTPδ is a presynaptic organizer for the formation and maintenance of climbing fiber to Purkinje cell synapses in the developing cerebellum

  Yuto Okuno; Kazuto Sakoori; Kyoko Matsuyama; Miwako Yamasaki; Masahiko Watanabe; Kouichi Hashimoto; Takaki Watanabe; Masanobu Kano

  Frontiers in Molecular Neuroscience Frontiers Media SA 16 2023/06
• Leucine-Rich Repeats and Transmembrane Domain 2 Controls Protein Sorting in the Striatal Projection System and Its Deficiency Causes Disturbances in Motor Responses and Monoamine Dynamics

  Misato Ichise; Kazuto Sakoori; Kei-ichi Katayama; Naoko Morimura; Kazuyuki Yamada; Hiroki Ozawa; Hayato Matsunaga; Minoru Hatayama; Jun Aruga

  FRONTIERS IN MOLECULAR NEUROSCIENCE FRONTIERS MEDIA SA 15 1662-5099 2022/05 [Refereed]
  
• Autism spectrum disorder-like behavior caused by reduced excitatory synaptic transmission in pyramidal neurons of mouse prefrontal cortex

  Hiroaki Sacai; Kazuto Sakoori; Kohtarou Konno; Kenichiro Nagahama; Honoka Suzuki; Takaki Watanabe; Masahiko Watanabe; Naofumi Uesaka; Masanobu Kano

  Nature Communications Springer Science and Business Media LLC 11 (1) 2020/12 [Refereed]
  
• Setd1a Insufficiency in Mice Attenuates Excitatory Synaptic Function and Recapitulates Schizophrenia-Related Behavioral Abnormalities.

  Kenichiro Nagahama; Kazuto Sakoori; Takaki Watanabe; Yusuke Kishi; Keita Kawaji; Michinori Koebis; Kazuki Nakao; Yukiko Gotoh; Atsu Aiba; Naofumi Uesaka; Masanobu Kano

  Cell reports 32 (11) 108126 - 108126 2020/09 [Refereed]
  
• Retrograde Signaling from Progranulin to Sort1 Counteracts Synapse Elimination in the Developing Cerebellum.

  Uesaka N; Abe M; Konno K; Yamazaki M; Sakoori K; Watanabe T; Kao TH; Mikuni T; Watanabe M; Sakimura K; Kano M

  Neuron 97 (4) 796 - 805.e5 0896-6273 2018/02 [Refereed]
  
• Corrigendum: Emerging roles of ARHGAP33 in intracellular trafficking of TrkB and pathophysiology of neuropsychiatric disorders.

  Nakazawa T; Hashimoto R; Sakoori K; Sugaya Y; Tanimura A; Hashimotodani Y; Ohi K; Yamamori H; Yasuda Y; Umeda-Yano S; Kiyama Y; Konno K; Inoue T; Yokoyama K; Inoue T; Numata S; Ohnuma T; Iwata N; Ozaki N; Hashimoto H; Watanabe M; Manabe T; Yamamoto T; Takeda M; Kano M

  Nature communications 7 11466  2016/04 [Refereed]
  
• Emerging roles of ARHGAP33 in intracellular trafficking of TrkB and pathophysiology of neuropsychiatric disorders

  Takanobu Nakazawa; Ryota Hashimoto; Kazuto Sakoori; Yuki Sugaya; Asami Tanimura; Yuki Hashimotodani; Kazutaka Ohi; Hidenaga Yamamori; Yuka Yasuda; Satomi Umeda-Yano; Yuji Kiyama; Kohtarou Konno; Takeshi Inoue; Kazumasa Yokoyama; Takafumi Inoue; Shusuke Numata; Tohru Ohnuma; Nakao Iwata; Norio Ozaki; Hitoshi Hashimoto; Masahiko Watanabe; Toshiya Manabe; Tadashi Yamamoto; Masatoshi Takeda; Masanobu Kano

  NATURE COMMUNICATIONS NATURE PUBLISHING GROUP 7 10594  2041-1723 2016/02 [Refereed]
  
• Rines E3 Ubiquitin Ligase Regulates MAO-A Levels and Emotional Responses

  Miyuki Kabayama; Kazuto Sakoori; Kazuyuki Yamada; Veravej G. Ornthanalai; Maya Ota; Naoko Morimura; Kei-ichi Katayama; Niall P. Murphy; Jun Aruga

  JOURNAL OF NEUROSCIENCE SOC NEUROSCIENCE 33 (32) 12940 - 12953 0270-6474 2013/08 [Refereed]
  
• SLITRK6 mutations cause myopia and deafness in humans and mice

  Mustafa Tekin; Barry A. Chioza; Yoshifumi Matsumoto; Oscar Diaz-Horta; Harold E. Cross; Duygu Duman; Haris Kokotas; Heather L. Moore-Barton; Kazuto Sakoori; Maya Ota; Yuri S. Odaka; Joseph Foster; F. Basak Cengiz; Suna Tokgoz-Yilmaz; Oya Tekeli; Maria Grigoriadou; Michael B. Petersen; Ajith Sreekantan-Nair; Kay Gurtz; Xia-Juan Xia; Arti Pandya; Michael A. Patton; Juan I. Young; Jun Aruga; Andrew H. Crosby

  JOURNAL OF CLINICAL INVESTIGATION AMER SOC CLINICAL INVESTIGATION INC 123 (5) 2094 - 2102 0021-9738 2013/05 [Refereed]
  
• Impaired Cognitive Function and Altered Hippocampal Synapse Morphology in Mice Lacking Lrrtm1, a Gene Associated with Schizophrenia

  Noriko Takashima; Yuri S. Odaka; Kazuto Sakoori; Takumi Akagi; Tsutomu Hashikawa; Naoko Morimura; Kazuyuki Yamada; Jun Aruga

  PLOS ONE PUBLIC LIBRARY SCIENCE 6 (7) e22716  1932-6203 2011/07 [Refereed]
  
• Zic2 hypomorphic mutant mice as a schizophrenia model and ZIC2 mutations identified in schizophrenia patients

  Minoru Hatayama; Akira Ishiguro; Yoshimi Iwayama; Noriko Takashima; Kazuto Sakoori; Tomoko Toyota; Yayoi Nozaki; Yuri S. Odaka; Kazuyuki Yamada; Takeo Yoshikawa; Jun Aruga

  SCIENTIFIC REPORTS NATURE PUBLISHING GROUP 1 16  2045-2322 2011/06 [Refereed]
  
• Executive dysfunction in novel environment and altered hippocampal synapse morphology in mice lacking Lrrtm1

  Takashima Noriko; Odaka Yuri; Sakoori Kazuto; Akagi Takumi; Hashikawa Tsutomu; Morimura Naoko; Yamada Kazuyuki; Aruga Jun

  Neuroscience Research 71 E284  2011 [Refereed]
  
• Reduced degeneration of dopaminergic terminals and accentuated astrocyte activation by high dose methamphetamine administration in nociceptin receptor knock out mice

  Kazuto Sakoori; Niall P. Murphy

  NEUROSCIENCE LETTERS ELSEVIER IRELAND LTD 469 (3) 309 - 313 0304-3940 2010/01 [Refereed]
  
• Enhanced nicotine sensitivity in nociceptin/orphanin FQ receptor knockout mice

  Kazuto Sakoori; Niall P. Murphy

  NEUROPHARMACOLOGY PERGAMON-ELSEVIER SCIENCE LTD 56 (5) 896 - 904 0028-3908 2009/04 [Refereed]
  
• Expression of morphine-conditioned place preference is more vulnerable than naloxone-conditioned place aversion to disruption by nociceptin in mice

  Kazuto Sakoori; Niall P. Murphy

  NEUROSCIENCE LETTERS ELSEVIER IRELAND LTD 443 (2) 108 - 112 0304-3940 2008/10 [Refereed]
  
• Endogenous nociceptin (orphanin FQ) suppresses basal hedonic state and acute reward responses to methamphetamine and ethanol, but facilitates chronic responses

  Kazuto Sakoori; Niall P. Murphy

  NEUROPSYCHOPHARMACOLOGY NATURE PUBLISHING GROUP 33 (4) 877 - 891 0893-133X 2008/03 [Refereed]
  
• Lack of evidence of a role for the neurosteroid allopregnanolone in ethanol-induced reward and c-fos expression in DBA/2 mice

  Niall P. Murphy; Kazuto Sakoori; Chinami Okabe

  BRAIN RESEARCH ELSEVIER SCIENCE BV 1094 (1) 107 - 118 0006-8993 2006/06 [Refereed]
  
• Maintenance of conditioned place preferences and aversion in C57BL6 mice: effects of repeated and drug state testing

  K Sakoori; NP Murphy

  BEHAVIOURAL BRAIN RESEARCH ELSEVIER SCIENCE BV 160 (1) 34 - 43 0166-4328 2005/05 [Refereed]
  
• The NOP (ORL1) receptor antagonist Compound B stimulates mesolimbic dopamine release and is rewarding in mice by a non-NOP-receptor-mediated mechanism

  M Koizumi; K Sakoori; N Midorikawa; NP Murphy

  BRITISH JOURNAL OF PHARMACOLOGY NATURE PUBLISHING GROUP 143 (1) 53 - 62 0007-1188 2004/09 [Refereed]
  
• Central administration of nociceptin/orphanin FQ blocks the acquisition of conditioned place preference to morphine and cocaine, but not conditioned place aversion to naloxone in mice

  K Sakoori; NP Murphy

  PSYCHOPHARMACOLOGY SPRINGER-VERLAG 172 (2) 129 - 136 0033-3158 2004/03 [Refereed]
  

Research Grants & Projects

• 内因性カンナビノイド2-AGが自閉スペクトラム症に及ぼす影響についての基礎的検討

  日本学術振興会：科学研究費助成事業

  Date (from‐to) : 2022/04 -2025/03 

  Author : 佐郡 和人