Researchers Database

Sakoori Kazuto

Faculty of Pharmaceutical Sciences Assistant Professor

Graduate School of Pharmaceutical Sciences Assistant Professor

Last Updated :2026/02/13

Faculty of Pharmaceutical Sciences Assistant Professor

Graduate School of Pharmaceutical Sciences Assistant Professor

PTPδ is a presynaptic organizer for the formation and maintenance of climbing fiber to Purkinje cell synapses in the developing cerebellum
Yuto Okuno; Kazuto Sakoori; Kyoko Matsuyama; Miwako Yamasaki; Masahiko Watanabe; Kouichi Hashimoto; Takaki Watanabe; Masanobu Kano
Frontiers in Molecular Neuroscience Frontiers Media SA 16 2023/06

Leucine-Rich Repeats and Transmembrane Domain 2 Controls Protein Sorting in the Striatal Projection System and Its Deficiency Causes Disturbances in Motor Responses and Monoamine Dynamics
Misato Ichise; Kazuto Sakoori; Kei-ichi Katayama; Naoko Morimura; Kazuyuki Yamada; Hiroki Ozawa; Hayato Matsunaga; Minoru Hatayama; Jun Aruga
FRONTIERS IN MOLECULAR NEUROSCIENCE 15 1662-5099 2022/05 [Refereed]

Autism spectrum disorder-like behavior caused by reduced excitatory synaptic transmission in pyramidal neurons of mouse prefrontal cortex
Hiroaki Sacai; Kazuto Sakoori; Kohtarou Konno; Kenichiro Nagahama; Honoka Suzuki; Takaki Watanabe; Masahiko Watanabe; Naofumi Uesaka; Masanobu Kano
Nature Communications Springer Science and Business Media LLC 11 (1) 2020/12 [Refereed]

Setd1a Insufficiency in Mice Attenuates Excitatory Synaptic Function and Recapitulates Schizophrenia-Related Behavioral Abnormalities.
Kenichiro Nagahama; Kazuto Sakoori; Takaki Watanabe; Yusuke Kishi; Keita Kawaji; Michinori Koebis; Kazuki Nakao; Yukiko Gotoh; Atsu Aiba; Naofumi Uesaka; Masanobu Kano
Cell reports 32 (11) 108126 - 108126 2020/09 [Refereed]

Retrograde Signaling from Progranulin to Sort1 Counteracts Synapse Elimination in the Developing Cerebellum.
Uesaka N; Abe M; Konno K; Yamazaki M; Sakoori K; Watanabe T; Kao TH; Mikuni T; Watanabe M; Sakimura K; Kano M
Neuron 97 (4) 796 - 805.e5 0896-6273 2018/02 [Refereed]

Emerging roles of ARHGAP33 in intracellular trafficking of TrkB and pathophysiology of neuropsychiatric disorders
Takanobu Nakazawa; Ryota Hashimoto; Kazuto Sakoori; Yuki Sugaya; Asami Tanimura; Yuki Hashimotodani; Kazutaka Ohi; Hidenaga Yamamori; Yuka Yasuda; Satomi Umeda-Yano; Yuji Kiyama; Kohtarou Konno; Takeshi Inoue; Kazumasa Yokoyama; Takafumi Inoue; Shusuke Numata; Tohru Ohnuma; Nakao Iwata; Norio Ozaki; Hitoshi Hashimoto; Masahiko Watanabe; Toshiya Manabe; Tadashi Yamamoto; Masatoshi Takeda; Masanobu Kano
NATURE COMMUNICATIONS 7 10594 2041-1723 2016/02 [Refereed]

Rines E3 Ubiquitin Ligase Regulates MAO-A Levels and Emotional Responses
Miyuki Kabayama; Kazuto Sakoori; Kazuyuki Yamada; Veravej G. Ornthanalai; Maya Ota; Naoko Morimura; Kei-ichi Katayama; Niall P. Murphy; Jun Aruga
JOURNAL OF NEUROSCIENCE 33 (32) 12940 - 12953 0270-6474 2013/08 [Refereed]

SLITRK6 mutations cause myopia and deafness in humans and mice
Mustafa Tekin; Barry A. Chioza; Yoshifumi Matsumoto; Oscar Diaz-Horta; Harold E. Cross; Duygu Duman; Haris Kokotas; Heather L. Moore-Barton; Kazuto Sakoori; Maya Ota; Yuri S. Odaka; Joseph Foster; F. Basak Cengiz; Suna Tokgoz-Yilmaz; Oya Tekeli; Maria Grigoriadou; Michael B. Petersen; Ajith Sreekantan-Nair; Kay Gurtz; Xia-Juan Xia; Arti Pandya; Michael A. Patton; Juan I. Young; Jun Aruga; Andrew H. Crosby
JOURNAL OF CLINICAL INVESTIGATION 123 (5) 2094 - 2102 0021-9738 2013/05 [Refereed]

Impaired Cognitive Function and Altered Hippocampal Synapse Morphology in Mice Lacking Lrrtm1, a Gene Associated with Schizophrenia
Noriko Takashima; Yuri S. Odaka; Kazuto Sakoori; Takumi Akagi; Tsutomu Hashikawa; Naoko Morimura; Kazuyuki Yamada; Jun Aruga
PLOS ONE 6 (7) e22716 1932-6203 2011/07 [Refereed]

Zic2 hypomorphic mutant mice as a schizophrenia model and ZIC2 mutations identified in schizophrenia patients
Minoru Hatayama; Akira Ishiguro; Yoshimi Iwayama; Noriko Takashima; Kazuto Sakoori; Tomoko Toyota; Yayoi Nozaki; Yuri S. Odaka; Kazuyuki Yamada; Takeo Yoshikawa; Jun Aruga
SCIENTIFIC REPORTS 1 16 2045-2322 2011/06 [Refereed]

Reduced degeneration of dopaminergic terminals and accentuated astrocyte activation by high dose methamphetamine administration in nociceptin receptor knock out mice
Kazuto Sakoori; Niall P. Murphy
NEUROSCIENCE LETTERS 469 (3) 309 - 313 0304-3940 2010/01 [Refereed]

Enhanced nicotine sensitivity in nociceptin/orphanin FQ receptor knockout mice
Kazuto Sakoori; Niall P. Murphy
NEUROPHARMACOLOGY 56 (5) 896 - 904 0028-3908 2009/04 [Refereed]

Expression of morphine-conditioned place preference is more vulnerable than naloxone-conditioned place aversion to disruption by nociceptin in mice
Kazuto Sakoori; Niall P. Murphy
NEUROSCIENCE LETTERS 443 (2) 108 - 112 0304-3940 2008/10 [Refereed]

Endogenous nociceptin (orphanin FQ) suppresses basal hedonic state and acute reward responses to methamphetamine and ethanol, but facilitates chronic responses
Kazuto Sakoori; Niall P. Murphy
NEUROPSYCHOPHARMACOLOGY 33 (4) 877 - 891 0893-133X 2008/03 [Refereed]

Lack of evidence of a role for the neurosteroid allopregnanolone in ethanol-induced reward and c-fos expression in DBA/2 mice
Niall P. Murphy; Kazuto Sakoori; Chinami Okabe
BRAIN RESEARCH 1094 (1) 107 - 118 0006-8993 2006/06 [Refereed]

Maintenance of conditioned place preferences and aversion in C57BL6 mice: effects of repeated and drug state testing
K Sakoori; NP Murphy
BEHAVIOURAL BRAIN RESEARCH 160 (1) 34 - 43 0166-4328 2005/05 [Refereed]

The NOP (ORL1) receptor antagonist Compound B stimulates mesolimbic dopamine release and is rewarding in mice by a non-NOP-receptor-mediated mechanism
M Koizumi; K Sakoori; N Midorikawa; NP Murphy
BRITISH JOURNAL OF PHARMACOLOGY 143 (1) 53 - 62 0007-1188 2004/09 [Refereed]

Central administration of nociceptin/orphanin FQ blocks the acquisition of conditioned place preference to morphine and cocaine, but not conditioned place aversion to naloxone in mice
K Sakoori; NP Murphy
PSYCHOPHARMACOLOGY 172 (2) 129 - 136 0033-3158 2004/03 [Refereed]