Kai Chieko

Researcher Information

Affiliation

Advanced Comprehensive Research Organization (ACRO) Specially Appointed Professor

Degree

• Ph.D.（1983 The University of Tokyo）

URL

https://jglobal.jst.go.jp/detail?JGLOBAL_ID=202201019492183117

Research funding number

• 10167330

J-Global ID

• 202201019492183117

Profile

• https://www.kailab.iis.u-tokyo.ac.jp/

Academic & Professional Experience

• 2024/10 - Today  Teikyo UniversityAdvanced Comprehensive Research Organization
• 2019/09 - 2024/03  The University of TokyoInstitute of Industrial Science
• 2005/04 - 2019/03  The University of Tokyo
• 2001/04 - 2019/03  The University of Tokyo
• 2000/04 - 2019/03  The University of TokyoThe Institute of Medical Science, Laboratory Animal Research Center
• 1999/10 - 2019/03  The University of TokyoThe Institute of Medical Science
• 2003/04 - 2004/03  The University of TokyoThe Institute of Medical Science
• 2002/04 - 2004/03  The University of Tokyoセンター長
• 1990/08 - 1999/09  The University of Tokyo
• 1983/11 - 1990/07  The University of TokyoThe Institute of Medical Science

Education

• 1980/04 - 1983/03  The University of Tokyo
• 1978/04 - 1980/03  The University of Tokyo
• 1976/04 - 1978/03  The University of Tokyo

Research Activity Information

Published Papers

• Single Dose of Attenuated Vaccinia Viruses Expressing H5 Hemagglutinin Affords Rapid and Long-Term Protection Against Lethal Infection with Highly Pathogenic Avian Influenza A H5N1 Virus in Mice and Monkeys.

  Fumihiko Yasui; Keisuke Munekata; Tomoko Fujiyuki; Takeshi Kuraishi; Kenzaburo Yamaji; Tomoko Honda; Sumiko Gomi; Misako Yoneda; Takahiro Sanada; Koji Ishii; Yoshihiro Sakoda; Hiroshi Kida; Shosaku Hattori; Chieko Kai; Michinori Kohara

  Vaccines 13 (1) 2025/01
• Expression of PVRL4, a molecular target for cancer treatment, is transcriptionally regulated by FOS.

  Tomoyuki Nanamiya; Kiyoko Takane; Kiyoshi Yamaguchi; Yuya Okawara; Mariko Arakawa; Akari Saku; Tsuneo Ikenoue; Tomoko Fujiyuki; Misako Yoneda; Chieko Kai; Yoichi Furukawa

  Oncology reports 51 (1) 2024/01
• Anti-tumor activity of a recombinant measles virus against canine lung cancer cells.

  Kei Tamura; Tomoko Fujiyuki; Kanako Moritoh; Hayato Akimoto; Keigo Iizuka; Hiroki Sato; Kazushi Asano; Misako Yoneda; Chieko Kai

  Scientific reports 13 (1) 18168 - 18168 2023/10
• Immune response elicited in the tumor microenvironment upon rMV-SLAMblind cancer virotherapy.

  Kanako Moritoh; Koichiro Shoji; Yosuke Amagai; Tomoko Fujiyuki; Hiroki Sato; Misako Yoneda; Chieko Kai

  Cancer science 2023/01
• Gene expression of Nectin-4 and its clinical significance in dogs with primary lung adenocarcinoma.

  Kei Tamura; Kumiko Ishigaki; Orie Yoshida; Terai Kazuyuki; Naoki Sakurai; Tatsuya Heishima; Tomoko Fujiyuki; Chieko Kai; Kazushi Asano

  Veterinary medicine and science 8 (5) 1922 - 1929 2022/07
• Behavioral sleep of geriatric squirrel monkeys (Saimiri boliviensis) in amami oshima, japan

  Sachi Sri Kantha; Juri Suzuki; Takeshi Kuraishi; Shosaku Hattori; Yasuo Kiso; Chieko Kai

  International Medical Journal Japan International Cultural Exchange Foundation 28 (5) 532 - 534 2436-3294 2021/10
• Downregulation of mitochondrial biogenesis by virus infection triggers antiviral responses by cyclic GMP-AMP synthase.

  Hiroki Sato; Miho Hoshi; Fusako Ikeda; Tomoko Fujiyuki; Misako Yoneda; Chieko Kai

  PLoS pathogens 17 (10) e1009841  2021/10
• Successful blastocyst production by intracytoplasmic injection of sperm after in vitro maturation of follicular oocytes obtained from immature female squirrel monkeys (Saimiri boliviensis).

  Shinichi Watanabe; Megumi Miura; Hiromi Morita; Moeka Nishi; Shin-Ichi Yokota; Shosaku Hattori; Hiromichi Matsumoto; Emiko Fukui; Ken Takeshi Kusakabe; Masanori Ochi; Naomi Nakagata; Yasuo Kiso; Chieko Kai; Midori Yoshizawa

  The Journal of reproduction and development 67 (4) 265 - 272 2021/08
• The Heterochromatin Block That Functions as a Rod Cell Microlens in Owl Monkeys Formed within a 15-Myr Time Span.

  Hideyuki Tanabe; Ken Takeshi Kusakabe; Hiroyuki Imai; Shin-Ichi Yokota; Takeshi Kuraishi; Shosaku Hattori; Chieko Kai; Akihiko Koga

  Genome biology and evolution 13 (3) 2021/03
• Recombinant SLAMblind Measles Virus Is a Promising Candidate for Nectin-4-Positive Triple Negative Breast Cancer Therapy.

  Tomoko Fujiyuki; Yosuke Amagai; Koichiro Shoji; Takeshi Kuraishi; Akihiro Sugai; Mutsumi Awano; Hiroki Sato; Shosaku Hattori; Misako Yoneda; Chieko Kai

  Molecular therapy oncolytics 19 127 - 135 2020/12
• Antitumor activity of an oncolytic measles virus against canine urinary bladder transitional cell carcinoma cells.

  Keigo Iizuka; Koichiro Shoji; Tomoko Fujiyuki; Kanako Moritoh; Kei Tamura; Asuka Yoshida; Hiroki Sato; Misako Yoneda; Kazushi Asano; Chieko Kai

  Research in veterinary science 133 313 - 317 2020/12
• PIM 3 kinase, a proto-oncogene product, regulates phosphorylation of the measles virus nucleoprotein tail domain at Ser 479 and Ser 510.

  Akihiro Sugai; Hiroki Sato; Misako Yoneda; Chieko Kai

  Biochemical and biophysical research communications 531 (3) 267 - 274 2020/10
• Comparative genomic analyses illuminate the distinct evolution of megabats within Chiroptera.

  Masato Nikaido; Shinji Kondo; Zicong Zhang; Jiaqi Wu; Hidenori Nishihara; Yoshihito Niimura; Shunta Suzuki; Kazushige Touhara; Yutaka Suzuki; Hideki Noguchi; Yohei Minakuchi; Atsushi Toyoda; Asao Fujiyama; Sumio Sugano; Misako Yoneda; Chieko Kai

  DNA research : an international journal for rapid publication of reports on genes and genomes 27 (4) 2020/08
• Induction of pluripotency in mammalian fibroblasts by cell fusion with mouse embryonic stem cells.

  Hiroyuki Imai; Ken Takeshi Kusakabe; Yasuo Kiso; Shosaku Hattori; Chieko Kai; Etsuro Ono; Kiyoshi Kano

  Biochemical and biophysical research communications 521 (1) 24 - 30 2020/01
• Pathological and genetic aspects of spontaneous mammary gland tumor in Tupaia belangeri (tree shrew).

  Chi Hai-Ying; Yuki Tanaka; Tatsuro Hifumi; Koichiro Shoji; Mohammad Enamul Hoque Kayesh; Md Abul Hashem; Bouchra Kitab; Takahiro Sanada; Tomoko Fujiyuki; Misako Yoneda; Hitoshi Hatai; Akira Yabuki; Noriaki Miyoshi; Chieko Kai; Michinori Kohara; Kyoko Tsukiyama-Kohara

  PloS one 15 (5) e0233232  2020
• Possible role of the Nipah virus V protein in the regulation of the interferon beta induction by interacting with UBX domain-containing protein1.

  Shotaro Uchida; Ryo Horie; Hiroki Sato; Chieko Kai; Misako Yoneda

  Scientific reports 8 (1) 7682 - 7682 2018/05
• Morphological analyses of the retinal photoreceptor cells in the nocturnally adapted owl monkeys.

  Nobue Kuniyoshi; Yuji Yoshida; Yoshiki Itoh; Shin-Ichi Yokota; Takeshi Kuraishi; Shosaku Hattori; Tomohiro Kondo; Midori Yoshizawa; Chieko Kai; Yasuo Kiso; Ken Takeshi Kusakabe

  The Journal of veterinary medical science 80 (3) 413 - 420 2018/03
• Nipah and Hendra Virus Nucleoproteins Inhibit Nuclear Accumulation of Signal Transducer and Activator of Transcription 1 (STAT1) and STAT2 by Interfering with Their Complex Formation.

  Akihiro Sugai; Hiroki Sato; Ikuyo Takayama; Misako Yoneda; Chieko Kai

  Journal of virology 91 (21) 2017/11
• Efficacy of recombinant measles virus expressing highly pathogenic avian influenza virus (HPAIV) antigen against HPAIV infection in monkeys.

  Tomoko Fujiyuki; Ryo Horie; Misako Yoneda; Takeshi Kuraishi; Fumihiko Yasui; Hyun-Jeong Kwon; Keisuke Munekata; Fusako Ikeda; Miho Hoshi; Yuri Kiso; Mio Omi; Hiroki Sato; Hiroshi Kida; Shosaku Hattori; Michinori Kohara; Chieko Kai

  Scientific reports 7 (1) 12017 - 12017 2017/09
• An integrated expression atlas of miRNAs and their promoters in human and mouse.

  Derek de Rie; Imad Abugessaisa; Tanvir Alam; Erik Arner; Peter Arner; Haitham Ashoor; Gaby Åström; Magda Babina; Nicolas Bertin; A Maxwell Burroughs; Ailsa J Carlisle; Carsten O Daub; Michael Detmar; Ruslan Deviatiiarov; Alexandre Fort; Claudia Gebhard; Daniel Goldowitz; Sven Guhl; Thomas J Ha; Jayson Harshbarger; Akira Hasegawa; Kosuke Hashimoto; Meenhard Herlyn; Peter Heutink; Kelly J Hitchens; Chung Chau Hon; Edward Huang; Yuri Ishizu; Chieko Kai; Takeya Kasukawa; Peter Klinken; Timo Lassmann; Charles-Henri Lecellier; Weonju Lee; Marina Lizio; Vsevolod Makeev; Anthony Mathelier; Yulia A Medvedeva; Niklas Mejhert; Christopher J Mungall; Shohei Noma; Mitsuhiro Ohshima; Mariko Okada-Hatakeyama; Helena Persson; Patrizia Rizzu; Filip Roudnicky; Pål Sætrom; Hiroki Sato; Jessica Severin; Jay W Shin; Rolf K Swoboda; Hiroshi Tarui; Hiroo Toyoda; Kristoffer Vitting-Seerup; Louise Winteringham; Yoko Yamaguchi; Kayoko Yasuzawa; Misako Yoneda; Noriko Yumoto; Susan Zabierowski; Peter G Zhang; Christine A Wells; Kim M Summers; Hideya Kawaji; Albin Sandelin; Michael Rehli; Yoshihide Hayashizaki; Piero Carninci; Alistair R R Forrest; Michiel J L de Hoon

  Nature biotechnology 35 (9) 872 - 878 2017/09
• FANTOM5 CAGE profiles of human and mouse samples.

  Shuhei Noguchi; Takahiro Arakawa; Shiro Fukuda; Masaaki Furuno; Akira Hasegawa; Fumi Hori; Sachi Ishikawa-Kato; Kaoru Kaida; Ai Kaiho; Mutsumi Kanamori-Katayama; Tsugumi Kawashima; Miki Kojima; Atsutaka Kubosaki; Ri-Ichiroh Manabe; Mitsuyoshi Murata; Sayaka Nagao-Sato; Kenichi Nakazato; Noriko Ninomiya; Hiromi Nishiyori-Sueki; Shohei Noma; Eri Saijyo; Akiko Saka; Mizuho Sakai; Christophe Simon; Naoko Suzuki; Michihira Tagami; Shoko Watanabe; Shigehiro Yoshida; Peter Arner; Richard A Axton; Magda Babina; J Kenneth Baillie; Timothy C Barnett; Anthony G Beckhouse; Antje Blumenthal; Beatrice Bodega; Alessandro Bonetti; James Briggs; Frank Brombacher; Ailsa J Carlisle; Hans C Clevers; Carrie A Davis; Michael Detmar; Taeko Dohi; Albert S B Edge; Matthias Edinger; Anna Ehrlund; Karl Ekwall; Mitsuhiro Endoh; Hideki Enomoto; Afsaneh Eslami; Michela Fagiolini; Lynsey Fairbairn; Mary C Farach-Carson; Geoffrey J Faulkner; Carmelo Ferrai; Malcolm E Fisher; Lesley M Forrester; Rie Fujita; Jun-Ichi Furusawa; Teunis B Geijtenbeek; Thomas Gingeras; Daniel Goldowitz; Sven Guhl; Reto Guler; Stefano Gustincich; Thomas J Ha; Masahide Hamaguchi; Mitsuko Hara; Yuki Hasegawa; Meenhard Herlyn; Peter Heutink; Kelly J Hitchens; David A Hume; Tomokatsu Ikawa; Yuri Ishizu; Chieko Kai; Hiroshi Kawamoto; Yuki I Kawamura; Judith S Kempfle; Tony J Kenna; Juha Kere; Levon M Khachigian; Toshio Kitamura; Sarah Klein; S Peter Klinken; Alan J Knox; Soichi Kojima; Haruhiko Koseki; Shigeo Koyasu; Weonju Lee; Andreas Lennartsson; Alan Mackay-Sim; Niklas Mejhert; Yosuke Mizuno; Hiromasa Morikawa; Mitsuru Morimoto; Kazuyo Moro; Kelly J Morris; Hozumi Motohashi; Christine L Mummery; Yutaka Nakachi; Fumio Nakahara; Toshiyuki Nakamura; Yukio Nakamura; Tadasuke Nozaki; Soichi Ogishima; Naganari Ohkura; Hiroshi Ohno; Mitsuhiro Ohshima; Mariko Okada-Hatakeyama; Yasushi Okazaki; Valerio Orlando; Dmitry A Ovchinnikov; Robert Passier; Margaret Patrikakis; Ana Pombo; Swati Pradhan-Bhatt; Xian-Yang Qin; Michael Rehli; Patrizia Rizzu; Sugata Roy; Antti Sajantila; Shimon Sakaguchi; Hiroki Sato; Hironori Satoh; Suzana Savvi; Alka Saxena; Christian Schmidl; Claudio Schneider; Gundula G Schulze-Tanzil; Anita Schwegmann; Guojun Sheng; Jay W Shin; Daisuke Sugiyama; Takaaki Sugiyama; Kim M Summers; Naoko Takahashi; Jun Takai; Hiroshi Tanaka; Hideki Tatsukawa; Andru Tomoiu; Hiroo Toyoda; Marc van de Wetering; Linda M van den Berg; Roberto Verardo; Dipti Vijayan; Christine A Wells; Louise N Winteringham; Ernst Wolvetang; Yoko Yamaguchi; Masayuki Yamamoto; Chiyo Yanagi-Mizuochi; Misako Yoneda; Yohei Yonekura; Peter G Zhang; Silvia Zucchelli; Imad Abugessaisa; Erik Arner; Jayson Harshbarger; Atsushi Kondo; Timo Lassmann; Marina Lizio; Serkan Sahin; Thierry Sengstag; Jessica Severin; Hisashi Shimoji; Masanori Suzuki; Harukazu Suzuki; Jun Kawai; Naoto Kondo; Masayoshi Itoh; Carsten O Daub; Takeya Kasukawa; Hideya Kawaji; Piero Carninci; Alistair R R Forrest; Yoshihide Hayashizaki

  Scientific data 4 170112 - 170112 2017/08
• Development of an ELISA for serological detection of feline morbillivirus infection.

  Kaho Arikawa; Akiko Wachi; Yuri Imura; Kripitch Sutummaporn; Chieko Kai; Eun-Sil Park; Shigeru Morikawa; Yosuke Uematsu; Tomohiro Yamaguchi; Tetsuya Furuya

  Archives of virology 162 (8) 2421 - 2425 2017/08
• Gene end-like sequences within the 3' non-coding region of the Nipah virus genome attenuate viral gene transcription.

  Akihiro Sugai; Hiroki Sato; Misako Yoneda; Chieko Kai

  Virology 508 36 - 44 2017/08
• The P gene of rodent brain-adapted measles virus plays a critical role in neurovirulence.

  Tetsuro Arai; Yuri Terao-Muto; Shotaro Uchida; Che Lin; Tomoyuki Honda; Akiko Takenaka; Fusako Ikeda; Hiroki Sato; Misako Yoneda; Chieko Kai

  The Journal of general virology 98 (7) 1620 - 1629 2017/07
• Corrigendum to 'Phagocytic cells contribute to the antibody-mediated elimination of pulmonary-infected SARS coronavirus' [Virology (2014) 157-168].

  Fumihiko Yasui; Michinori Kohara; Masahiro Kitabatake; Tetsu Nishiwaki; Hideki Fujii; Chise Tateno; Misako Yoneda; Kouichi Morita; Kouji Matsushima; Shigeo Koyasu; Chieko Kai

  Virology 499 397 - 398 2016/12
• Measles virus induces persistent infection by autoregulation of viral replication.

  Tomomitsu Doi; Hyun-Jeong Kwon; Tomoyuki Honda; Hiroki Sato; Misako Yoneda; Chieko Kai

  Scientific reports 6 37163 - 37163 2016/11
• Measles virus selectively blind to signaling lymphocyte activity molecule has oncolytic efficacy against nectin-4-expressing pancreatic cancer cells.

  Mutsumi Awano; Tomoko Fujiyuki; Koichiro Shoji; Yosuke Amagai; Yoshinori Murakami; Yoichi Furukawa; Hiroki Sato; Misako Yoneda; Chieko Kai

  Cancer science 107 (11) 1647 - 1652 2016/11
• Infectious Progression of Canine Distemper Virus from Circulating Cerebrospinal Fluid into the Central Nervous System.

  Akiko Takenaka; Hiroki Sato; Fusako Ikeda; Misako Yoneda; Chieko Kai

  Journal of virology 90 (20) 9285 - 92 2016/10
• Region of Nipah virus C protein responsible for shuttling between the cytoplasm and nucleus.

  Ryo Horie; Misako Yoneda; Shotaro Uchida; Hiroki Sato; Chieko Kai

  Virology 497 294 - 304 2016/10
• Eukaryotic elongation factor 1-beta interacts with the 5' untranslated region of the M gene of Nipah virus to promote mRNA translation.

  Shotaro Uchida; Hiroki Sato; Misako Yoneda; Chieko Kai

  Archives of virology 161 (9) 2361 - 8 2016/09
• Intracytoplasmic sperm injection into oocytes matured in vitro and early embryonic development in the owl monkey (Aotus lemurinus).

  Hideaki Watanabe; Takuya Matsumoto; Moeka Nishi; Ken Takeshi Kusakabe; Takeshi Kuraishi; Shosaku Hattori; Hiromichi Matsumoto; Emiko Fukui; Akiko Kuwahata; Masanori Ochi; Yasuo Kiso; Chieko Kai; Midori Yoshizawa

  Reproductive medicine and biology 15 (3) 183 - 186 2016/07
• Amyloidosis enhancing activity of bovine amyloid A fibrils in C3H/HeN mice and cynomolgus monkeys (Macaca fascicularis).

  Satomi Tsukawaki; Tomoaki Murakami; Kanata Ibi; Takeshi Kuraishi; Shosaku Hattori; Chieko Kai; Kazuhiko Suzuki; Tokuma Yanai

  Journal of medical primatology 45 (3) 112 - 7 2016/06
• Oncolytic Activity of a Recombinant Measles Virus, Blind to Signaling Lymphocyte Activation Molecule, Against Colorectal Cancer Cells.

  Yosuke Amagai; Tomoko Fujiyuki; Misako Yoneda; Koichiro Shoji; Yoichi Furukawa; Hiroki Sato; Chieko Kai

  Scientific reports 6 24572 - 24572 2016/04
• Report on the use of non-clinical studies in the regulatory evaluation of oncology drugs.

  Yoshihiro Hayakawa; Manabu Kawada; Hiroyoshi Nishikawa; Takahiro Ochiya; Hideyuki Saya; Hiroyuki Seimiya; Ryoji Yao; Masahiro Hayashi; Chieko Kai; Akira Matsuda; Tomoki Naoe; Atsushi Ohtsu; Taku Okazaki; Hideo Saji; Masataka Sata; Haruhiko Sugimura; Yuichi Sugiyama; Masakazu Toi; Tatsuro Irimura

  Cancer science 107 (2) 189 - 202 2016/02
• Histocytological specificities of adrenal cortex in the New World Monkeys, Aotus lemurinus and Saimiri boliviensis.

  Toru Tachibana; Ken Takeshi Kusakabe; Sayuri Osaki; Takeshi Kuraishi; Shosaku Hattori; Midori Yoshizawa; Chieko Kai; Yasuo Kiso

  The Journal of veterinary medical science 78 (1) 161 - 5 2016/01
• Development of new therapy for canine mammary cancer with recombinant measles virus.

  Koichiro Shoji; Misako Yoneda; Tomoko Fujiyuki; Yosuke Amagai; Akane Tanaka; Akira Matsuda; Kikumi Ogihara; Yuko Naya; Fusako Ikeda; Hiroshi Matsuda; Hiroki Sato; Chieko Kai

  Molecular therapy oncolytics 3 15022 - 15022 2016
• Measles Virus Infection Inactivates Cellular Protein Phosphatase 5 with Consequent Suppression of Sp1 and c-Myc Activities.

  Hiroki Sato; Misako Yoneda; Reiko Honma; Fusako Ikeda; Shinya Watanabe; Chieko Kai

  Journal of virology 89 (19) 9709 - 18 2015/10
• A measles virus selectively blind to signaling lymphocytic activation molecule shows anti-tumor activity against lung cancer cells.

  Tomoko Fujiyuki; Misako Yoneda; Yosuke Amagai; Kunie Obayashi; Fusako Ikeda; Koichiro Shoji; Yoshinori Murakami; Hiroki Sato; Chieko Kai

  Oncotarget 6 (28) 24895 - 903 2015/09
• Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells.

  Erik Arner; Carsten O Daub; Kristoffer Vitting-Seerup; Robin Andersson; Berit Lilje; Finn Drabløs; Andreas Lennartsson; Michelle Rönnerblad; Olga Hrydziuszko; Morana Vitezic; Tom C Freeman; Ahmad M N Alhendi; Peter Arner; Richard Axton; J Kenneth Baillie; Anthony Beckhouse; Beatrice Bodega; James Briggs; Frank Brombacher; Margaret Davis; Michael Detmar; Anna Ehrlund; Mitsuhiro Endoh; Afsaneh Eslami; Michela Fagiolini; Lynsey Fairbairn; Geoffrey J Faulkner; Carmelo Ferrai; Malcolm E Fisher; Lesley Forrester; Daniel Goldowitz; Reto Guler; Thomas Ha; Mitsuko Hara; Meenhard Herlyn; Tomokatsu Ikawa; Chieko Kai; Hiroshi Kawamoto; Levon M Khachigian; S Peter Klinken; Soichi Kojima; Haruhiko Koseki; Sarah Klein; Niklas Mejhert; Ken Miyaguchi; Yosuke Mizuno; Mitsuru Morimoto; Kelly J Morris; Christine Mummery; Yutaka Nakachi; Soichi Ogishima; Mariko Okada-Hatakeyama; Yasushi Okazaki; Valerio Orlando; Dmitry Ovchinnikov; Robert Passier; Margaret Patrikakis; Ana Pombo; Xian-Yang Qin; Sugata Roy; Hiroki Sato; Suzana Savvi; Alka Saxena; Anita Schwegmann; Daisuke Sugiyama; Rolf Swoboda; Hiroshi Tanaka; Andru Tomoiu; Louise N Winteringham; Ernst Wolvetang; Chiyo Yanagi-Mizuochi; Misako Yoneda; Susan Zabierowski; Peter Zhang; Imad Abugessaisa; Nicolas Bertin; Alexander D Diehl; Shiro Fukuda; Masaaki Furuno; Jayson Harshbarger; Akira Hasegawa; Fumi Hori; Sachi Ishikawa-Kato; Yuri Ishizu; Masayoshi Itoh; Tsugumi Kawashima; Miki Kojima; Naoto Kondo; Marina Lizio; Terrence F Meehan; Christopher J Mungall; Mitsuyoshi Murata; Hiromi Nishiyori-Sueki; Serkan Sahin; Sayaka Nagao-Sato; Jessica Severin; Michiel J L de Hoon; Jun Kawai; Takeya Kasukawa; Timo Lassmann; Harukazu Suzuki; Hideya Kawaji; Kim M Summers; Christine Wells; David A Hume; Alistair R R Forrest; Albin Sandelin; Piero Carninci; Yoshihide Hayashizaki

  Science (New York, N.Y.) 347 (6225) 1010 - 4 2015/02
• Morphological characterization of spermatozoa of the night monkey.

  Nakazato C; Yoshizawa M; Isobe K; Kusakabe K; Kuraishi T; Hattori S; Matsumoto H; Fukui E; Kuwahata A; Ochi M; Kiso Y; Kai C

  J. Mamm. Ova Res. 日本卵子学会 32 (1) 37 - 40 1341-7738 2015 [Refereed]
  
• Morphological characterization and in vitro maturation of follicular oocytes from the owl monkey (Aotus lemurinus)

  Takuya Matsumoto; Keisuke Isobe; Ken Takeshi Kusakabe; Takeshi Kuraishi; Shosaku Hattori; Chiho Nakazato; Hiromichi Matsumoto; Emiko Fukui; Akiko Kuwahata; Masanori Ochi; Yasuo Kiso; Chieko Kai; Midori Yoshizawa

  Journal of Mammalian Ova Research Japanese Society of Mammalian Ova Research 32 (3) 103 - 108 1347-5878 2015 [Refereed]
  
• Efficacy of Recombinant Canine Distemper Virus Expressing Leishmania Antigen against Leishmania Challenge in Dogs.

  Ryuichi Miura; Takanori Kooriyama; Misako Yoneda; Akiko Takenaka; Miho Doki; Yasuyuki Goto; Chizu Sanjoba; Yasuyuki Endo; Tomoko Fujiyuki; Akihiro Sugai; Kyoko Tsukiyama-Kohara; Yoshitsugu Matsumoto; Hiroki Sato; Chieko Kai

  PLoS neglected tropical diseases 9 (7) e0003914  2015
• Characterization of two recent Japanese field isolates of canine distemper virus and examination of the avirulent strain utility as an attenuated vaccine.

  Akiko Takenaka; Misako Yoneda; Takahiro Seki; Masashi Uema; Takanori Kooriyama; Toshiya Nishi; Kentaro Fujita; Ryuichi Miura; Kyoko Tsukiyama-Kohara; Hiroki Sato; Chieko Kai

  Veterinary microbiology 174 (3-4) 372 - 381 2014/12
• Characterization of the mitochondrial genome of Rousettus leschenaulti.

  Michał Szcześniak; Misako Yoneda; Hiroki Sato; Izabela Makałowska; Shigeru Kyuwa; Sumio Sugano; Yutaka Suzuki; Wojciech Makałowski; Chieko Kai

  Mitochondrial DNA 25 (6) 443 - 4 2014/12
• Failure of heterogeneous amyloid-enhancing factor in geriatric squirrel monkeys (Saimiri boliviensis).

  Tomoaki Murakami; Kanata Ibi; Takeshi Kuraishi; Shosaku Hattori; Chieko Kai; Naotaka Ishiguro; Tokuma Yanai

  Journal of medical primatology 43 (6) 488 - 91 2014/12
• Construction of an expression system for bioactive IL-18 and generation of recombinant canine distemper virus expressing IL-18.

  Yuxiu Liu; Hiroki Sato; Masahiro Hamana; Navita Anisia Moonan; Misako Yoneda; Xianzhu Xia; Chieko Kai

  The Journal of veterinary medical science 76 (9) 1241 - 8 2014/09
• 新世界ザルの眼における比較形態学的研究

  吉田 優司; 日下部 健; 伊藤 良樹; 倉石 武; 服部 正策; 吉澤 緑; 甲斐 知恵子; 檜山 雅人; 加納 聖; 木曾 康郎

  日本獣医学会学術集会講演要旨集 (公社)日本獣医学会 157回 329 - 329 1347-8621 2014/08
• Phagocytic cells contribute to the antibody-mediated elimination of pulmonary-infected SARS coronavirus.

  Fumihiko Yasui; Michinori Kohara; Masahiro Kitabatake; Tetsu Nishiwaki; Hideki Fujii; Chise Tateno; Misako Yoneda; Kouichi Morita; Kouji Matsushima; Shigeo Koyasu; Chieko Kai

  Virology 454-455 157 - 68 2014/04
• A promoter-level mammalian expression atlas.

  Alistair R R Forrest; Hideya Kawaji; Michael Rehli; J Kenneth Baillie; Michiel J L de Hoon; Vanja Haberle; Timo Lassmann; Ivan V Kulakovskiy; Marina Lizio; Masayoshi Itoh; Robin Andersson; Christopher J Mungall; Terrence F Meehan; Sebastian Schmeier; Nicolas Bertin; Mette Jørgensen; Emmanuel Dimont; Erik Arner; Christian Schmidl; Ulf Schaefer; Yulia A Medvedeva; Charles Plessy; Morana Vitezic; Jessica Severin; Colin A Semple; Yuri Ishizu; Robert S Young; Margherita Francescatto; Intikhab Alam; Davide Albanese; Gabriel M Altschuler; Takahiro Arakawa; John A C Archer; Peter Arner; Magda Babina; Sarah Rennie; Piotr J Balwierz; Anthony G Beckhouse; Swati Pradhan-Bhatt; Judith A Blake; Antje Blumenthal; Beatrice Bodega; Alessandro Bonetti; James Briggs; Frank Brombacher; A Maxwell Burroughs; Andrea Califano; Carlo V Cannistraci; Daniel Carbajo; Yun Chen; Marco Chierici; Yari Ciani; Hans C Clevers; Emiliano Dalla; Carrie A Davis; Michael Detmar; Alexander D Diehl; Taeko Dohi; Finn Drabløs; Albert S B Edge; Matthias Edinger; Karl Ekwall; Mitsuhiro Endoh; Hideki Enomoto; Michela Fagiolini; Lynsey Fairbairn; Hai Fang; Mary C Farach-Carson; Geoffrey J Faulkner; Alexander V Favorov; Malcolm E Fisher; Martin C Frith; Rie Fujita; Shiro Fukuda; Cesare Furlanello; Masaaki Furino; Jun-ichi Furusawa; Teunis B Geijtenbeek; Andrew P Gibson; Thomas Gingeras; Daniel Goldowitz; Julian Gough; Sven Guhl; Reto Guler; Stefano Gustincich; Thomas J Ha; Masahide Hamaguchi; Mitsuko Hara; Matthias Harbers; Jayson Harshbarger; Akira Hasegawa; Yuki Hasegawa; Takehiro Hashimoto; Meenhard Herlyn; Kelly J Hitchens; Shannan J Ho Sui; Oliver M Hofmann; Ilka Hoof; Furni Hori; Lukasz Huminiecki; Kei Iida; Tomokatsu Ikawa; Boris R Jankovic; Hui Jia; Anagha Joshi; Giuseppe Jurman; Bogumil Kaczkowski; Chieko Kai; Kaoru Kaida; Ai Kaiho; Kazuhiro Kajiyama; Mutsumi Kanamori-Katayama; Artem S Kasianov; Takeya Kasukawa; Shintaro Katayama; Sachi Kato; Shuji Kawaguchi; Hiroshi Kawamoto; Yuki I Kawamura; Tsugumi Kawashima; Judith S Kempfle; Tony J Kenna; Juha Kere; Levon M Khachigian; Toshio Kitamura; S Peter Klinken; Alan J Knox; Miki Kojima; Soichi Kojima; Naoto Kondo; Haruhiko Koseki; Shigeo Koyasu; Sarah Krampitz; Atsutaka Kubosaki; Andrew T Kwon; Jeroen F J Laros; Weonju Lee; Andreas Lennartsson; Kang Li; Berit Lilje; Leonard Lipovich; Alan Mackay-Sim; Ri-ichiroh Manabe; Jessica C Mar; Benoit Marchand; Anthony Mathelier; Niklas Mejhert; Alison Meynert; Yosuke Mizuno; David A de Lima Morais; Hiromasa Morikawa; Mitsuru Morimoto; Kazuyo Moro; Efthymios Motakis; Hozumi Motohashi; Christine L Mummery; Mitsuyoshi Murata; Sayaka Nagao-Sato; Yutaka Nakachi; Fumio Nakahara; Toshiyuki Nakamura; Yukio Nakamura; Kenichi Nakazato; Erik van Nimwegen; Noriko Ninomiya; Hiromi Nishiyori; Shohei Noma; Shohei Noma; Tadasuke Noazaki; Soichi Ogishima; Naganari Ohkura; Hiroko Ohimiya; Hiroshi Ohno; Mitsuhiro Ohshima; Mariko Okada-Hatakeyama; Yasushi Okazaki; Valerio Orlando; Dmitry A Ovchinnikov; Arnab Pain; Robert Passier; Margaret Patrikakis; Helena Persson; Silvano Piazza; James G D Prendergast; Owen J L Rackham; Jordan A Ramilowski; Mamoon Rashid; Timothy Ravasi; Patrizia Rizzu; Marco Roncador; Sugata Roy; Morten B Rye; Eri Saijyo; Antti Sajantila; Akiko Saka; Shimon Sakaguchi; Mizuho Sakai; Hiroki Sato; Suzana Savvi; Alka Saxena; Claudio Schneider; Erik A Schultes; Gundula G Schulze-Tanzil; Anita Schwegmann; Thierry Sengstag; Guojun Sheng; Hisashi Shimoji; Yishai Shimoni; Jay W Shin; Christophe Simon; Daisuke Sugiyama; Takaai Sugiyama; Masanori Suzuki; Naoko Suzuki; Rolf K Swoboda; Peter A C 't Hoen; Michihira Tagami; Naoko Takahashi; Jun Takai; Hiroshi Tanaka; Hideki Tatsukawa; Zuotian Tatum; Mark Thompson; Hiroo Toyodo; Tetsuro Toyoda; Elvind Valen; Marc van de Wetering; Linda M van den Berg; Roberto Verado; Dipti Vijayan; Ilya E Vorontsov; Wyeth W Wasserman; Shoko Watanabe; Christine A Wells; Louise N Winteringham; Ernst Wolvetang; Emily J Wood; Yoko Yamaguchi; Masayuki Yamamoto; Misako Yoneda; Yohei Yonekura; Shigehiro Yoshida; Susan E Zabierowski; Peter G Zhang; Xiaobei Zhao; Silvia Zucchelli; Kim M Summers; Harukazu Suzuki; Carsten O Daub; Jun Kawai; Peter Heutink; Winston Hide; Tom C Freeman; Boris Lenhard; Vladimir B Bajic; Martin S Taylor; Vsevolod J Makeev; Albin Sandelin; David A Hume; Piero Carninci; Yoshihide Hayashizaki

  Nature 507 (7493) 462 - 70 2014/03
• Infectivity of Cryptosporidium andersoni and Cryptosporidium muris to normal and immunosuppressive cynomolgus monkeys.

  Koichi Masuno; Yasuhiro Fukuda; Masahito Kubo; Ryo Ikarashi; Takeshi Kuraishi; Shosaku Hattori; Junpei Kimura; Chieko Kai; Tokuma Yanai; Yutaka Nakai

  The Journal of veterinary medical science 76 (2) 169 - 72 2014/03
• Long noncoding RNA NEAT1-dependent SFPQ relocation from promoter region to paraspeckle mediates IL8 expression upon immune stimuli.

  Katsutoshi Imamura; Naoto Imamachi; Gen Akizuki; Michiko Kumakura; Atsushi Kawaguchi; Kyosuke Nagata; Akihisa Kato; Yasushi Kawaguchi; Hiroki Sato; Misako Yoneda; Chieko Kai; Tetsushi Yada; Yutaka Suzuki; Toshimichi Yamada; Takeaki Ozawa; Kiyomi Kaneki; Tsuyoshi Inoue; Mika Kobayashi; Tatsuhiko Kodama; Youichiro Wada; Kazuhisa Sekimizu; Nobuyoshi Akimitsu

  Molecular cell 53 (3) 393 - 406 2014/02
• Newly identified minor phosphorylation site threonine-279 of measles virus nucleoprotein is a prerequisite for nucleocapsid formation.

  Akihiro Sugai; Hiroki Sato; Kyoji Hagiwara; Hiroko Kozuka-Hata; Masaaki Oyama; Misako Yoneda; Chieko Kai

  Journal of virology 88 (2) 1140 - 9 2014/01
• Phosphorylation of measles virus nucleoprotein affects viral growth by changing gene expression and genomic RNA stability.

  Akihiro Sugai; Hiroki Sato; Misako Yoneda; Chieko Kai

  Journal of virology 87 (21) 11684 - 92 2013/11
• Pathological features of Cryptosporidium andersoni-induced lesions in SCID mice.

  Koichi Masuno; Tokuma Yanai; Hiroki Sakai; Masaaki Satoh; Chieko Kai; Yutaka Nakai

  Experimental parasitology 134 (3) 381 - 3 2013/07
• Downregulation of Nipah virus N mRNA occurs through interaction between its 3' untranslated region and hnRNP D.

  Kimihiro Hino; Hiroki Sato; Akihiro Sugai; Masahiko Kato; Misako Yoneda; Chieko Kai

  Journal of virology 87 (12) 6582 - 8 2013/06
• Measles virus selectively blind to signaling lymphocyte activation molecule as a novel oncolytic virus for breast cancer treatment.

  T Sugiyama; M Yoneda; T Kuraishi; S Hattori; Y Inoue; H Sato; C Kai

  Gene therapy 20 (3) 338 - 47 2013/03 [Refereed]
  
• バイオディフェンス-免疫システム分子制御の新たな局面 新規アジュバント添加による次世代SE36マラリアワクチンの開発と実用化 旅行者用ワクチンへのアプローチ

  東岸 任弘; 青枝 大貴; Coban Cevayir; 片貝 祐子; 甲斐 知恵子; 保富 康宏; 石井 健; 堀井 俊宏

  日本薬学会年会要旨集 (公社)日本薬学会 133年会 (1) 93 - 93 0918-9823 2013/03
• TLR9 adjuvants enhance immunogenicity and protective efficacy of the SE36/AHG malaria vaccine in nonhuman primate models.

  Takahiro Tougan; Taiki Aoshi; Cevayir Coban; Yuko Katakai; Chieko Kai; Yasuhiro Yasutomi; Ken J Ishii; Toshihiro Horii

  Human vaccines & immunotherapeutics 9 (2) 283 - 90 2013/02
• Recombinant measles virus vaccine expressing the Nipah virus glycoprotein protects against lethal Nipah virus challenge.

  Misako Yoneda; Marie-Claude Georges-Courbot; Fusako Ikeda; Miho Ishii; Noriyo Nagata; Frederic Jacquot; Hervé Raoul; Hiroki Sato; Chieko Kai

  PloS one 8 (3) e58414  2013
• Experimental infection of macaques with a wild water bird-derived highly pathogenic avian influenza virus (H5N1).

  Tomoko Fujiyuki; Misako Yoneda; Fumihiko Yasui; Takeshi Kuraishi; Shosaku Hattori; Hyun-Jeong Kwon; Keisuke Munekata; Yuri Kiso; Hiroshi Kida; Michinori Kohara; Chieko Kai

  PloS one 8 (12) e83551  2013
• Phosphorylation of measles virus phosphoprotein at S86 and/or S151 downregulates viral transcriptional activity.

  Akihiro Sugai; Hiroki Sato; Misako Yoneda; Chieko Kai

  FEBS letters 586 (21) 3900 - 7 2012/11
• The 9th International Veterinary Immunology Symposium.

  Joan K Lunney; Chieko Kai; Shigeki Inumaru; Takashi Onodera

  Veterinary immunology and immunopathology 148 (1-2) 1 - 5 2012/07
• The nucleocapsid protein of measles virus blocks host interferon response.

  Ikuyo Takayama; Hiroki Sato; Akira Watanabe; Mio Omi-Furutani; Akihiro Sugai; Keita Kanki; Misako Yoneda; Chieko Kai

  Virology 424 (1) 45 - 55 2012/03
• Phylogenetic relationships of three species within the family Heligmonellidae (Nematoda; Heligmosomoidea) from Japanese rodents and a lagomorph based on the sequences of ribosomal DNA internal transcribed spacers, ITS-1 and ITS-2.

  Seitaro Yamada; Atushi Yoshida; Keiko Yoshida; Takeshi Kuraishi; Shosaku Hattori; Chieko Kai; Yumiko Nagai; Takeshi Sakoda; Masaya Tatara; Shintaro Abe; Shin-ichiro Fukumoto

  The Japanese journal of veterinary research 60 (1) 15 - 21 0047-1917 2012/02
• Morbillivirus receptors and tropism: multiple pathways for infection.

  Hiroki Sato; Misako Yoneda; Tomoyuki Honda; Chieko Kai

  Frontiers in microbiology 3 75 - 75 2012
• Recombinant vaccines against the mononegaviruses--what we have learned from animal disease controls.

  Hiroki Sato; Misako Yoneda; Tomoyuki Honda; Chieko Kai

  Virus research 162 (1-2) 63 - 71 2011/12
• Monoclonal antibody 2-152a suppresses hepatitis C virus infection through betaine/GABA transporter-1.

  Masaaki Satoh; Makoto Saito; Takashi Takano; Yuri Kasama; Tomohiro Nishimura; Yasumasa Nishito; Yuichi Hirata; Masaaki Arai; Masayuki Sudoh; Chieko Kai; Michinori Kohara; Kyoko Tsukiyama-Kohara

  The Journal of infectious diseases 204 (8) 1172 - 80 2011/10
• Determination of a phosphorylation site in Nipah virus nucleoprotein and its involvement in virus transcription.

  Mingshu Huang; Hiroki Sato; Kyoji Hagiwara; Akira Watanabe; Akihiro Sugai; Fusako Ikeda; Hiroko Kozuka-Hata; Masaaki Oyama; Misako Yoneda; Chieko Kai

  The Journal of general virology 92 (Pt 9) 2133 - 2141 2011/09
• Translocase of outer mitochondrial membrane 70 expression is induced by hepatitis C virus and is related to the apoptotic response.

  Takashi Takano; Michinori Kohara; Yuri Kasama; Tomohiro Nishimura; Makoto Saito; Chieko Kai; Kyoko Tsukiyama-Kohara

  Journal of medical virology 83 (5) 801 - 9 2011/05
• Peroxiredoxin 1 is required for efficient transcription and replication of measles virus.

  Akira Watanabe; Misako Yoneda; Fusako Ikeda; Akihiro Sugai; Hiroki Sato; Chieko Kai

  Journal of virology 85 (5) 2247 - 53 2011/03
• Cynomolgus monkeys (Macaca fascicularis) may not become infected with equine herpesvirus 9.

  Atsushi Kodama; Tokuma Yanai; Masahito Kubo; Nagwan El-Habashi; Samy Kasem; Hiroki Sakai; Toshiaki Masegi; Hideto Fukushi; Takeshi Kuraishi; Misako Yoneda; Shosaku Hattori; Chieko Kai

  Journal of medical primatology 40 (1) 18 - 20 2011/02
• Selective translation of the measles virus nucleocapsid mRNA by la protein.

  Yoshihisa Inoue; Hiroki Sato; Kentaro Fujita; Kyoko Tsukiyama-Kohara; Misako Yoneda; Chieko Kai

  Frontiers in microbiology 2 173 - 173 2011
• Evaluation of a recombinant measles virus expressing hepatitis C virus envelope proteins by infection of human PBL-NOD/Scid/Jak3null mouse.

  Masaaki Satoh; Makoto Saito; Kohsuke Tanaka; Sumako Iwanaga; Salem Nagla Elwy Salem Ali; Takahiro Seki; Seiji Okada; Michinori Kohara; Shinji Harada; Chieko Kai; Kyoko Tsukiyama-Kohara

  Comparative immunology, microbiology and infectious diseases 33 (6) e81-8  2010/12
• Novel phosphoprotein-interacting region in Nipah virus nucleocapsid protein and its involvement in viral replication.

  Mio Omi-Furutani; Misako Yoneda; Kentaro Fujita; Fusako Ikeda; Chieko Kai

  Journal of virology 84 (19) 9793 - 9 2010/10
• The nonstructural proteins of Nipah virus play a key role in pathogenicity in experimentally infected animals.

  Misako Yoneda; Vanessa Guillaume; Hiroki Sato; Kentaro Fujita; Marie-Claude Georges-Courbot; Fusako Ikeda; Mio Omi; Yuri Muto-Terao; T Fabian Wild; Chieko Kai

  PloS one 5 (9) e12709  2010/09
• CD147/EMMPRIN acts as a functional entry receptor for measles virus on epithelial cells.

  Akira Watanabe; Misako Yoneda; Fusako Ikeda; Yuri Terao-Muto; Hiroki Sato; Chieko Kai

  Journal of virology 84 (9) 4183 - 93 2010/05
• Comparative and mutational analyses of promoter regions of rinderpest virus.

  Chieko Imai; Kentaro Fujita; Fusako Shimizu; Akihiro Sugai; Misako Yoneda; Chieko Kai

  Virology 396 (2) 169 - 77 2010/01
• Analysis of the mechanism by which BALB/c mice having prior immunization with nucleocapsid protein of SARS-CoV develop severe pneumonia after SARS-CoV infection.

  Fumihiko Yasui; Chieko Kai; Kousuke Saito; Shingo Inoue; Misako Yoneda; Kouichi Morita; Kyosuke Mizuno; Michinori Kohara

  Procedia in vaccinology 2 (1) 44 - 50 2010
• Hepatitis C virus impairs p53 via persistent overexpression of 3beta-hydroxysterol Delta24-reductase.

  Tomohiro Nishimura; Michinori Kohara; Kosuke Izumi; Yuri Kasama; Yuichi Hirata; Ying Huang; Masahiro Shuda; Chise Mukaidani; Takashi Takano; Yuko Tokunaga; Hideko Nuriya; Masaaki Satoh; Makoto Saito; Chieko Kai; Kyoko Tsukiyama-Kohara

  The Journal of biological chemistry 284 (52) 36442 - 36452 2009/12
• Epitope mapping of Canine distemper virus phosphoprotein by monoclonal antibodies.

  Akihiro Sugai; Takanori Kooriyama; Hiroki Sato; Misako Yoneda; Chieko Kai

  Microbiology and immunology 53 (12) 667 - 74 2009/12
• Pathological and phylogenetic features of prevalent canine distemper viruses in wild masked palm civets in Japan.

  Ikuyo Takayama; Masahito Kubo; Akiko Takenaka; Kentaro Fujita; Takaaki Sugiyama; Tetsuro Arai; Misako Yoneda; Hiroki Sato; Tokuma Yanai; Chieko Kai

  Comparative immunology, microbiology and infectious diseases 32 (6) 539 - 49 2009/11
• Hepatitis C virus-core protein facilitates the degradation of Ku70 and reduces DNA-PK activity in hepatocytes.

  Kentarou Saitou; Kiyohisa Mizumoto; Tomohiro Nishimura; Chieko Kai; Kyoko Tsukiyama-Kohara

  Virus research 144 (1-2) 266 - 71 2009/09
• Inhibition of host protein synthesis in B95a cells infected with the HL strain of measles virus.

  Yoshihisa Inoue; Kyoko Tsukiyama-Kohara; Misako Yoneda; Hiroki Sato; Chieko Kai

  Comparative immunology, microbiology and infectious diseases 32 (1) 29 - 41 2009/01
• Reverse genetics of Nipah virus to probe viral pathogenicity.

  Misako Yoneda; Kentaro Fujita; Hiroki Sato; Chieko Kai

  Methods in molecular biology (Clifton, N.J.) 515 329 - 37 2009
• Heparin-like glycosaminoglycans prevent the infection of measles virus in SLAM-negative cell lines.

  Yuri Terao-Muto; Misako Yoneda; Takahiro Seki; Akira Watanabe; Kyoko Tsukiyama-Kohara; Kentaro Fujita; Chieko Kai

  Antiviral research 80 (3) 370 - 6 2008/12
• Prior immunization with severe acute respiratory syndrome (SARS)-associated coronavirus (SARS-CoV) nucleocapsid protein causes severe pneumonia in mice infected with SARS-CoV.

  Fumihiko Yasui; Chieko Kai; Masahiro Kitabatake; Shingo Inoue; Misako Yoneda; Shoji Yokochi; Ryoichi Kase; Satoshi Sekiguchi; Kouichi Morita; Tsunekazu Hishima; Hidenori Suzuki; Katsuo Karamatsu; Yasuhiro Yasutomi; Hisatoshi Shida; Minoru Kidokoro; Kyosuke Mizuno; Kouji Matsushima; Michinori Kohara

  Journal of immunology (Baltimore, Md. : 1950) 181 (9) 6337 - 48 2008/11
• Measles virus induces cell-type specific changes in gene expression.

  Hiroki Sato; Reiko Honma; Misako Yoneda; Ryuichi Miura; Kyoko Tsukiyama-Kohara; Fusako Ikeda; Takahiro Seki; Shinya Watanabe; Chieko Kai

  Virology 375 (2) 321 - 30 2008/06
• Phosphorylation of measles virus nucleoprotein upregulates the transcriptional activity of minigenomic RNA.

  Kyoji Hagiwara; Hiroki Sato; Yoshihisa Inoue; Akira Watanabe; Misako Yoneda; Fusako Ikeda; Kentaro Fujita; Hiroyuki Fukuda; Chizuko Takamura; Hiroko Kozuka-Hata; Masaaki Oyama; Sumio Sugano; Shinobu Ohmi; Chieko Kai

  Proteomics 8 (9) 1871 - 9 2008/05
• Immune responses against measles virus in cynomolgus monkeys.

  Hiroki Sato; Fumio Kobune; Yasushi Ami; Misako Yoneda; Chieko Kai

  Comparative immunology, microbiology and infectious diseases 31 (1) 25 - 35 0147-9571 2008/01
• Acute neuropathogenicity with experimental infection of equine herpesvirus 9 in common marmosets (Callithrix jacchus)

  A. Kodama; T. Yanai; K. Yomemaru; H. Sakai; T. Masegi; S. Yamada; H. Fukushi; T. Kuraishi; S. Hattori; C. Kai

  Journal of Medical Primatology BLACKWELL PUBLISHING 36 (6) 335 - 342 0047-2565 2007/12 [Refereed]
  
• Measles virus N protein inhibits host translation by binding to eIF3-p40.

  Hiroki Sato; Munemitsu Masuda; Moeko Kanai; Kyoko Tsukiyama-Kohara; Misako Yoneda; Chieko Kai

  Journal of virology 81 (21) 11569 - 76 0022-538X 2007/11
• A novel monolayer cell line derived from human umbilical cord blood cells shows high sensitivity to measles virus.

  Fumio Kobune; Yasushi Ami; Miki Katayama; Motohide Takahashi; Renchin Tuul; Gulay Korukluoglu; Tomoko Kiyohara; Ryuichi Miura; Hiroki Sato; Misako Yoneda; Chieko Kai

  The Journal of general virology 88 (Pt 5) 1565 - 1567 2007/05
• Host range and receptor utilization of canine distemper virus analyzed by recombinant viruses: Involvement of heparin-like molecule in CDV infection.

  Kentaro Fujita; Ryuichi Miura; Misako Yoneda; Fusako Shimizu; Hiroki Sato; Yuri Muto; Yasuyuki Endo; Kyoko Tsukiyama-Kohara; Chieko Kai

  Virology 359 (2) 324 - 35 0042-6822 2007/03
• Chimeric VEGF-ENZ7/PlGF specifically binding to VEGFR-2 accelerates skin wound healing via enhancement of neovascularization.

  Yujuan Zheng; Makoto Watanabe; Takeshi Kuraishi; Shosaku Hattori; Chieko Kai; Masabumi Shibuya

  Arteriosclerosis, thrombosis, and vascular biology 27 (3) 503 - 11 2007/03
• Seroepidemiological survey of morbillivirus infection in Kuril harbor seals (Phoca vitulina stejnegeri) of Hokkaido, Japan.

  Kei Fujii; Hiroki Sato; Chiharu Kakumoto; Mari Kobayashi; Sachiko Saito; Tatsuya Kariya; Yukiko Watanabe; Yoshihiro Sakoda; Chieko Kai; Hiroshi Kida; Masatsugu Suzuki

  The Japanese journal of veterinary research 54 (2-3) 109 - 17 0047-1917 2006/11
• Establishment of a Nipah virus rescue system.

  Misako Yoneda; Vanessa Guillaume; Fusako Ikeda; Yuki Sakuma; Hiroki Sato; T Fabian Wild; Chieko Kai

  Proceedings of the National Academy of Sciences of the United States of America 103 (44) 16508 - 13 0027-8424 2006/10
• Imaging living mice using a 1-T compact MRI system.

  Yusuke Inoue; Yukihiro Nomura; Tomoyuki Haishi; Kohki Yoshikawa; Takahiro Seki; Kyoko Tsukiyama-Kohara; Chieko Kai; Toshiyuki Okubo; Kuni Ohtomo

  Journal of magnetic resonance imaging : JMRI 24 (4) 901 - 7 1053-1807 2006/10
• Morbillivirus nucleoprotein possesses a novel nuclear localization signal and a CRM1-independent nuclear export signal.

  Hiroki Sato; Munemitsu Masuda; Ryuichi Miura; Misako Yoneda; Chieko Kai

  Virology 352 (1) 121 - 30 0042-6822 2006/08
• Canine distemper virus induces apoptosis through caspase-3 and-8 activation in Vero cells

  M. Kajita; H. Katayama; T. Murata; C. Kai; M. Hori; H. Ozaki

  JOURNAL OF VETERINARY MEDICINE SERIES B-INFECTIOUS DISEASES AND VETERINARY PUBLIC HEALTH BLACKWELL PUBLISHING 53 (6) 273 - 277 0931-1793 2006/08 [Refereed]
  
• Sequence analysis of VP2 gene of canine parvovirus isolated from domestic dogs in Japan in 1999 and 2000.

  Miho Doki; Kentaro Fujita; Ryuichi Miura; Misako Yoneda; Yoshihisa Ishikawa; Akira Taneno; Chieko Kai

  Comparative immunology, microbiology and infectious diseases 29 (4) 199 - 206 0147-9571 2006/07
• Characterization of monoclonal antibodies directed against the canine distemper virus nucleocapsid protein

  M Masuda; H Sato; H Kamata; T Katsuo; A Takenaka; R Miura; M Yoneda; K Tsukiyama-Kohara; K Mizumoto; C Kai

  COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES PERGAMON-ELSEVIER SCIENCE LTD 29 (2-3) 157 - 165 0147-9571 2006/03 [Refereed]
  
• Immunology of rinderpest - an immunosuppression but a lifelong vaccine protection

  S. Louise Cosby; Chieko Kai; Kazuya Yamanouchi

  Rinderpest and Peste des Petits Ruminants Elsevier Ltd 196 - 221 2006
• ウマヘルペスウイルス9型(EHV-9)のコモンマーモセット(Callitbrix jaccbus)における病原性

  児玉 篤史; 柳井 徳磨; 福士 秀人; 山田 壮一; 酒井 洋樹; 柵木 利昭; 倉石 一; 服部 正策; 甲斐 知恵子

  日本獣医学会学術集会講演要旨集 (公社)日本獣医学会 140回 64 - 64 1347-8621 2005/08
• Measles virus infection induces interleukin-8 release in human pulmonary epithelial cells.

  Hiroki Sato; Ryuichi Miura; Chieko Kai

  Comparative immunology, microbiology and infectious diseases 28 (4) 311 - 20 0147-9571 2005/07
• Phylogenetic and restriction fragment length polymorphism analyses of hemagglutinin (H) protein of canine distemper virus isolates from domestic dogs in Japan.

  Masashi Uema; Kenjiro Ohashi; Chiaki Wakasa; Chieko Kai

  Virus research 109 (1) 59 - 63 0168-1702 2005/04
• The effect of recombinant swine interleukin-4 on swine immune cells and on pro-inflammatory cytokine productions in pigs

  A Nuntaprasert; Y Mori; Y Muneta; K Yoshihara; K Tsukiyama-Kohara; C Kai

  COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES PERGAMON-ELSEVIER SCIENCE LTD 28 (2) 83 - 101 0147-9571 2005/03 [Refereed]
  
• Expression and characterization of the recombinant swine interleukin-6

  A Nuntaprasert; Y Mori; K Fujita; M Yoneda; R Miura; K Tsukiyama-Kohara; C Kai

  COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES PERGAMON-ELSEVIER SCIENCE LTD 28 (2) 103 - 120 0147-9571 2005/03 [Refereed]
  
• Establishment of swine interleukin-6 sandwich ELISA

  A Nuntaprasert; Y Mori; K Tsukiyama-Kohara; C Kai

  COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES PERGAMON-ELSEVIER SCIENCE LTD 28 (2) 121 - 130 0147-9571 2005/03 [Refereed]
  
• Expression and purification of recombinant swine interleukin-4

  A Nuntaprasert; Y Mori; K Fujita; M Yoneda; R Miura; K Tsukiyama-Kohara; C Kai

  COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES PERGAMON-ELSEVIER SCIENCE LTD 28 (1) 17 - 35 0147-9571 2005/01 [Refereed]
  
• Phylogenetic analysis of the hemagglutinin (H) gene of canine distemper viruses isolated from wild masked palm civets (Paguma larvata).

  Kyoko Hirama; Yoko Goto; Masashi Uema; Yasuyuki Endo; Ryuichi Miura; Chieko Kai

  The Journal of veterinary medical science 66 (12) 1575 - 8 0916-7250 2004/12
• Prevalence of canine distemper virus, feline immunodeficiency virus and feline leukemia virus in captive African lions (Panthera leo) in Japan.

  Yasuyuki Endo; Masashi Uema; Ryuichi Miura; Kyoko Tsukiyama-Kohara; Hajime Tsujimoto; Kumiko Yoneda; Chieko Kai

  The Journal of veterinary medical science 66 (12) 1587 - 9 0916-7250 2004/12
• [Nipah virus infections].

  Chieko Kai

  Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 93 (11) 2341 - 6 0021-5384 2004/11
• Characterization of specific antibodies and the establishment of sandwich ELISA and ELISPOT systems for swine IL-4

  A Nuntaprasert; Y Mori; K Fujita; M Yoneda; R Miura; K Tsukiyama-Kohara; C Kai

  COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES PERGAMON-ELSEVIER SCIENCE LTD 27 (6) 457 - 470 0147-9571 2004/11 [Refereed]
  
• Involvement of apoptosis in syncytial cell death induced by canine distemper virus

  T Nishi; K Tsukiyama-Kohara; K Togashi; N Kohriyama; C Kai

  COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES PERGAMON-ELSEVIER SCIENCE LTD 27 (6) 445 - 455 0147-9571 2004/11 [Refereed]
  
• Rinderpest virus phosphoprotein gene is a major determinant of species-specific pathogenicity.

  Misako Yoneda; Ryuichi Miura; Thomas Barrett; Kyoko Tsukiyama-Kohara; Chieko Kai

  Journal of virology 78 (12) 6676 - 81 0022-538X 2004/06
• Role of actin microfilaments in canine distemper virus replication in vero cells.

  Hideo Katayama; Masatoshi Hori; Koichi Sato; Masahiro Kajita; Hiroshi Ozaki; Hideaki Karaki; Kenjiro Ohashi; Chieko Kai

  The Journal of veterinary medical science 66 (4) 409 - 15 0916-7250 2004/04
• [Nipah virus infection].

  Chieko Kai

  Nihon rinsho. Japanese journal of clinical medicine 61 Suppl 2 292 - 5 0047-1852 2003/02
• Cytotoxic T-lymphocyte activity specific for hemagglutinin (H) protein of canine distemper virus in dogs.

  Kyoko Hirama; Ken-ichi Togashi; Chiaki Wakasa; Misako Yoneda; Toshiya Nishi; Yasuyuki Endo; Ryuichi Miura; Kyoko Tsukiyama-Kohara; Chieko Kai

  The Journal of veterinary medical science 65 (1) 109 - 12 0916-7250 2003/01
• Ganglioglioma in the thalamus of a puppy.

  Kazuyuki Uchida; Hiroyuki Nakayama; Yasuyuki Endo; Chieko Kai; Shigeyuki Tatewaki; Ryoji Yamaguchi; Kunio Doi; Susumu Tateyama

  The Journal of veterinary medical science 65 (1) 113 - 5 0916-7250 2003/01
• Rinderpest virus H protein: role in determining host range in rabbits

  M. Yoneda; S. K. Bandyopadhyay; M. Shiotani; K. Fujita; A. Nuntaprasert; R. Miura; M. D. Baron; T. Barrett; C. Kai

  Journal of General Virology Microbiology Society 83 (6) 1457 - 1463 0022-1317 2002/06
• Seroprevalence of canine distemper virus in cats

  Y Ikeda; K Nakamura; T Miyazawa; MC Chen; TF Kuo; JA Lin; T Mikami; C Kai; E Takahashi

  CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY AMER SOC MICROBIOLOGY 8 (3) 641 - 644 1071-412X 2001/05 [Refereed]
  
• Properties of a new CDV isolate from a raccoon dog (Nyctereutes procyonoides viverrinus) in Japan

  K Ohashi; K Iwatsuki; K Murata; M Miyashita; Y Hukumoto; K Nakamura; C Wakasa; E Takahashi; C Kai

  VETERINARY RECORD BRITISH VETERINARY ASSOC 148 (5) 148 - 150 0042-4900 2001/02 [Refereed]
  
• Molecular Properties of the Matrixprotein(M) Gene of the Lapinized Rinderpest Virus

  Motohiro Shiotani; Ryuichi Miura; Kentaro Fujita; Chiaki Wakasa; Masashi Uema; Chieko Kai

  Journal of Veterinary Medical Science 63 (7) 801 - 805 0916-7250 2001
• Antigenic differences in the H proteins of canine distemper viruses

  K Iwatsuki; S Tokiyoshi; N Hirayama; K Nakamura; K Ohashi; C Wakasa; T Mikami; C Kai

  VETERINARY MICROBIOLOGY ELSEVIER SCIENCE BV 71 (3-4) 281 - 286 0378-1135 2000/02 [Refereed]
  
• Sequence analysis of the genes encoding the phosphoprotein of recent isolates of canine distemper virus in Japan

  C Wakasa; K Iwatsuki; K Ohashi; K Nakamura; C Kai

  JOURNAL OF VETERINARY MEDICAL SCIENCE JAPAN SOC VET SCI 62 (1) 97 - 101 0916-7250 2000/01 [Refereed]
  
• Establishment of a persistent mutant of canine distemper virus

  K Iwatsuki; Y Ikeda; K Ohashi; K Nakamura; C Kai

  MICROBES AND INFECTION EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER 1 (12) 987 - 991 1286-4579 1999/10 [Refereed]
  
• Identification of the Marek's Disease Virus Serotype 2 Genes Homologous to the Glycoprotein B (UL27), ICP18.5 (UL28) and Major DNA-Binding Protein (UL29) Genes of Herpes Simplex Virus Type 1

  Kentaro Kato; Hyung-Kwan Jang; Yoshihiro Izumiya; Jin-Shun Cai; Yoshinori Tsushima; Takayuki Miyazawa; Chieko Kai; Takeshi Mikami

  Journal of Veterinary Medical Science 61 (10) 1161 - 1165 1782-155X 1999/10 [Refereed]
  
• Identification and transcriptional analysis of the homologues of the herpes simplex virus type 1 UL30 to UL40 genes in the genome of nononcogenic Marek's disease virus serotype 2.

  Yoshihiro Izumiya; Hyung-Kwan Jang; Mie Sugawara; Yasuhiro Ikeda; Ryuichi Miura; Yorihiro Nishimura; Kazuya Nakamura; Takayuki Miyazawa; Chieko Kai; Takeshi Mikami

  The Journal of general virology 80 ( Pt 9) 2417 - 2422 1999/09
• Identification and sequence analysis of the Marek's disease virus serotype 2 homologous genes of the herpes simplex virus type 1 UL25, UL26 and UL26.5 genes

  K Kato; HK Jang; Y Izumiya; JS Cai; Y Tsushima; T Miyazawa; C Kai; T Mikami

  JOURNAL OF VETERINARY MEDICAL SCIENCE JAPAN SOC VET SCI 61 (7) 787 - 793 0916-7250 1999/07 [Refereed]
  
• Identification and Sequence Analysis of the Marek's Disease Virus Serotype 2 Homologous Genes of the Herpes Simplex Virus Type 1 UL25, UL26 and UL26.5 Genes

  Kentaro Kato; Hyung-Kwan Jang; Yoshihiro Izumiya; Jin-Shun Cai; Yoshinori Tsushima; Takayuki Miyazawa; Chieko Kai; Takeshi Mikami

  Journal of Veterinary Medical Science 61 (7) 787 - 793 1782-155X 1999/07 [Refereed]
  
• Identification and sequence analysis of the Marek's disease virus serotype 2 gene homologous to the herpes simplex virus type 1 UL52 protein

  Y Izumiya; HK Jang; JS Cai; Y Nishimura; K Nakamura; Y Tsushima; K Kato; T Miyazawa; C Kai; T Mikami

  JOURNAL OF VETERINARY MEDICAL SCIENCE JAPAN SOC VET SCI 61 (6) 683 - 687 0916-7250 1999/06 [Refereed]
  
• Identification and DNA sequence analysis of the Marek's disease virus serotype 2 genes homologous to the herpes simplex virus type 1 UL20 and UL21

  S Hatama; HK Jang; Y Izumiya; JS Cai; Y Tsushima; K Kato; T Miyazawa; C Kai; E Takahashi; T Mikami

  JOURNAL OF VETERINARY MEDICAL SCIENCE JAPAN SOC VET SCI 61 (6) 587 - 593 0916-7250 1999/06 [Refereed]
  
• Identification and sequence analysis of the Marek's disease virus serotype 2 gene homologous to the herpes simplex virus type 1 UL52 protein

  Yoshihiro Izumiya; Hyung-Kwan Jang; Jin-Shun Cai; Yorihiro Nishimura; Kazuya Nakamura; Yoshinori Tsushima; Kentaro Kato; Takayuki Miyazawa; Chieko Kai; Takeshi Mikami

  Journal of Veterinary Medical Science 61 (6) 683 - 687 1782-155X 1999/06 [Refereed]
  
• Identification and DNA sequence analysis of the Marek's disease virus serotype 2 genes homologous to the herpes simplex virus type 1 UL20 and UL21

  Shinichi Hatama; Hyung-Kwan Jang; Yoshihiro Izumiya; Jin-Shun Cai; Yoshinori Tsushima; Kentaro Kato; Takayuki Miyazawa; Chieko Kai; Eiji Takahashi; Takeshi Mikami

  Journal of Veterinary Medical Science 61 (6) 587 - 593 1782-155X 1999/06 [Refereed]
  
• Epitopes and nuclear localization analyses of canine distemper virus nucleocapsid protein by expression of its deletion mutants

  E Yoshida; YS Shin; K Iwatsuki; T Gemma; N Miyashita; K Tomonaga; N Hirayama; T Mikami; C Kai

  VETERINARY MICROBIOLOGY ELSEVIER SCIENCE BV 66 (4) 313 - 320 0378-1135 1999/05 [Refereed]
  
• Identification and structure of the Marek's disease virus serotype 2 glycoprotein M gene: Comparison with glycoprotein M genes of Herpesviridae family

  JS Cai; HK Jang; Y Izumiya; Y Tsushima; K Kato; AM Damiani; T Miyazawa; C Kai; E Takahashi; T Mikami

  JOURNAL OF VETERINARY MEDICAL SCIENCE JAPAN SOC VET SCI 61 (5) 503 - 511 0916-7250 1999/05 [Refereed]
  
• Identification and Structure of the Marek's Disease Virus Serotype 2 Glycoprotein M Gene: Comparison with Glycoprotein M Genes of Herpesviridae Family

  Jin-Shun Cai; Hyung-Kwan Jang; Yoshihiro Izumiya; Yoshinori Tsushima; Kentaro Kato; Armando M. Damiani; Takayuki Miyazawa; Chieko Kai; Eiji Takahashi; Takeshi Mikami

  Journal of Veterinary Medical Science 61 (5) 503 - 511 1782-155X 1999/05 [Refereed]
  
• Molecular cloning and sequence analysis of the phosphoprotein (P) gene of the lapinized rinderpest virus

  K Nakamura; K Iwatsuki; Y Izumiya; Y Nishimura; K Ohashi; T Mikami; C Kai

  VIRUS GENES KLUWER ACADEMIC PUBL 18 (2) 175 - 178 0920-8569 1999/04 [Refereed]
  
• Gene arrangement and RNA transcription of the BamHI fragments K and M2 within the non-oncogenic Marek's disease virus serotype 2 unique long genome region

  Y Tsushima; HK Jang; Y Izumiya; JS Cai; K Kato; T Miyazawa; C Kai; E Takahashi; T Mikami

  VIRUS RESEARCH ELSEVIER SCIENCE BV 60 (1) 101 - 110 0168-1702 1999/03 [Refereed]
  
• Feline immunodeficiency virus subtype C is prevalent in northern part of Taiwan

  M Uema; Y Ikeda; T Miyazawa; JA Lin; MC Chen; TF Kuo; C Kai; T Mikami; E Takahashi

  JOURNAL OF VETERINARY MEDICAL SCIENCE JAPAN SOC VET SCI 61 (2) 197 - 199 0916-7250 1999/02 [Refereed]
  
• Development of restriction fragment-length polymorphism method to differentiate five subtypes of feline immunodeficiency virus

  Kyoko Kurosawa; Yasuhiro Ikeda; Takayuki Miyazawa; Yoshihiro Izumiya; Yorihiro Nishimura; Kazuya Nakamura; Eiji Sato; Takeshi Mikami; Chieko Kai; Eiji Takahashi

  Microbiology and Immunology Center for Academic Publications Japan 43 (8) 817 - 820 0385-5600 1999
• New approaches to the development of virus vaccines for veterinary use.

  K Yamanouchi; T Barrett; C Kai

  Revue scientifique et technique (International Office of Epizootics) 17 (3) 641 - 53 0253-1933 1998/12
• Molecular identification of a recent type of canine distemper virus in Japan by restriction fragment length polymorphism

  K Ohashi; K Iwatsuki; K Nakamura; T Mikami; C Kai

  JOURNAL OF VETERINARY MEDICAL SCIENCE JAPAN SOC VET SCI 60 (11) 1209 - 1212 0916-7250 1998/11 [Refereed]
  
• Identification and transcriptional analysis of the homologues of the herpes simplex virus type 1 UL41 to UL51 genes in the genome of nononcogenic Marek's disease virus serotype 2

  Y Izumiya; HK Jang; H Kashiwase; JS Cai; Y Nishimura; Y Tsushima; K Kato; T Miyazawa; C Kai; T Mikami

  JOURNAL OF GENERAL VIROLOGY SOC GENERAL MICROBIOLOGY 79 1997 - 2001 0022-1317 1998/08 [Refereed]
  
• Construction of recombinant vaccinia virus expressing Rinderpest Virus nucleocapsid protein and its immunogenicity in mice.

  K Ohishi; H Kamata; S Ohkubo; K Yamanouchi; C Kai

  The Journal of veterinary medical science 60 (5) 655 - 6 0916-7250 1998/05
• Immunizing effect of vaccinia virus expressing the nucleoprotein of rinderpest virus on systemic rinderpest virus infection in rabbits.

  K Nakamura; K Ohishi; S Ohkubo; H Kamata; K Yamanouchi; K Fujiwara; C Kai

  Comparative immunology, microbiology and infectious diseases 21 (2) 91 - 9 0147-9571 1998/04
• Nucleotide Sequences of Glycoprotein I and E Genes of Equine Herpesvirus Type 4

  Armando Mario Damiani; Tomio Matsumura; Naoaki Yokoyama; Ken Maeda; Takayuki Miyazawa; Chieko Kai; Takeshi Mikami

  Journal of Veterinary Medical Science JAPAN SOC VET SCI 60 (2) 219 - 225 0916-7250 1998/02
• Molecular analysis of the nucleocapsid protein of recent isolates of canine distemper virus in Japan

  E Yoshida; K Iwatsuki; N Miyashita; T Gemma; C Kai; T Mikami

  VETERINARY MICROBIOLOGY ELSEVIER SCIENCE BV 59 (2-3) 237 - 244 0378-1135 1998/01 [Refereed]
  
• In vitro recombination of feline herpesvirus type 1

  K. Fujita; K. Maeda; N. Yokoyama; T. Miyazawa; C. Kai; T. Mikami

  Archives of Virology SPRINGER-VERLAG WIEN 143 (1) 25 - 34 0304-8608 1998
• Protein-binding properties of the putative AP-1 and ATF sequences in the feline immunodeficiency virus long terminal repeat

  Y Ikeda; Y Inoshima; Y Kawaguchi; K Maeda; M Kohmoto; C Kai; T Miyazawa; T Mikami

  JOURNAL OF GENERAL VIROLOGY SOC GENERAL MICROBIOLOGY 79 95 - 99 0022-1317 1998/01
• New Quantitative Methods for Detection of Feline Parvovirus (FPV) and Virus Neutralizing Antibody against FPV Using a Feline T Lymphoid Cell Line

  Yasuhiro Ikeda; Takayuki Miyazawa; Kyoko Kurosawa; Risako Naito; Shinichi Hatama; Chieko Kai; Takeshi Mikami

  Journal of Veterinary Medical Science Maruzen Co. Ltd. 60 (8) 973 - 974 0916-7250 1998 [Refereed]
  
• The effects of treatment with chemical agents or infection with feline viruses on protein-binding properties of the feline immunodeficiency virus long terminal repeat

  Yasuhiro Ikeda; Yasushi Kawaguchi; Yasuo Inoshima; Mariko Kohmoto; Masayuki Shimojima; Gouki Inada; Eiji Sato; Chieko Kai; Takayuki Miyazawa; Takeshi Mikami

  Virus Research 51 (2) 203 - 212 0168-1702 1997/10 [Refereed]
  
• Histopathological features of canine distemper recently observed in Japan.

  M Okita; T Yanai; F Ochikubo; T Gemma; T Mori; T Maseki; K Yamanouchi; T Mikami; C Kai

  Journal of comparative pathology 116 (4) 403 - 8 0021-9975 1997/05
• Molecular and phylogenetic analyses of the haemagglutinin (H) proteins of field isolates of canine distemper virus from naturally infected dogs

  K Iwatsuki; N Miyashita; E Yoshida; T Gemma; YS Shin; T Mori; N Hirayama; C Kai; T Mikami

  JOURNAL OF GENERAL VIROLOGY SOC GENERAL MICROBIOLOGY 78 373 - 380 0022-1317 1997/02 [Refereed]
  
• Identification and DNA Sequence Analysis of the Marek's Disease Virus Serotype 2 Gene Homologous to the Herpes Simplex Virus Type 1 Glycoprotein H.

  Yukako SHIMOJIMA; Hyung-Kwan JANG; Mitsuru ONO; Chieko KAI; Takeshi MIKAMI

  Journal of Veterinary Medical Science Japanese Society of Veterinary Science 59 (8) 629 - 634 0916-7250 1997 [Refereed]
  
• Expression of the nucleocapsid protein gene of the canine distemper virus

  YS Shin; T Mori; K Tomonaga; K Iwatsuki; C Kai; T Mikami

  JOURNAL OF VETERINARY MEDICAL SCIENCE JAPAN SOC VET SCI 59 (1) 51 - 53 0916-7250 1997/01 [Refereed]
  
• Roles of the auxiliary genes and AP-1 binding site in the long terminal repeat of feline immunodeficiency virus in the early stage of infection in cats

  Y Inoshima; M Kohmoto; Y Ikeda; H Yamada; Y Kawaguchi; K Tomonaga; T Miyazawa; C Kai; T Umemura; T Mikami

  JOURNAL OF VIROLOGY AMER SOC MICROBIOLOGY 70 (12) 8518 - 8526 0022-538X 1996/12 [Refereed]
  
• Genetic diversity of Argentine isolates of feline immunodeficiency virus

  Marcelo R. Pecoraro; Keizo Tomonaga; Takayuki Miyazawa; Yasushi Kawaguchi; Shigeo Sugita; Yukinobu Tohya; Chieko Kai; Maria E. Etcheverrigaray; Takeshi Mikami

  Journal of General Virology 77 (9) 2031 - 2035 0022-1317 1996/09 [Refereed]
  
• Serological analysis of canine distemper virus using an immunocapture ELISA

  T Gemma; K Iwatsuki; YS Shin; E Yoshida; C Kai; T Mikami

  JOURNAL OF VETERINARY MEDICAL SCIENCE JAPAN SOC VET SCI 58 (8) 791 - 794 0916-7250 1996/08 [Refereed]
  
• Feline immunodeficiency virus can infect a human cell line (MOLT-4) but establishes a state of latency in the cells

  Yasuhiro Ikeda; Keizo Tomonaga; Yasushi Kawaguchi; Mariko Kohmoto; Yasuo Inoshima; Yukinobu Tohya; Takayuki Miyazawa; Chieko Kai; Takeshi Mikami

  Journal of General Virology 77 (8) 1623 - 1630 0022-1317 1996/08 [Refereed]
  
• Epidemiological observations on recent outbreaks of canine distemper in Tokyo area

  T Gemma; T Watari; K Akiyama; N Miyashita; YS Shin; K Iwatsuki; C Kai; T Mikami

  JOURNAL OF VETERINARY MEDICAL SCIENCE JAPAN SOC VET SCI 58 (6) 547 - 550 0916-7250 1996/06 [Refereed]
  
• Molecular cloning of the feline CD8β-chain

  M. R. Pecoraro; M. Shimojima; K. Maeda; Y. Inoshima; Y. Kawaguchi; C. Kai; T. Mikami

  Immunology BLACKWELL SCIENCE LTD 89 (1) 84 - 88 0019-2805 1996
• Nucleotide sequences of the M gene of prevailing wild measles viruses and a comparison with subacute sclerosing panencephalitis virus.

  C Kai; K Yamanouchi; H Sakata; N Miyashita; H Takahashi; F Kobune

  Virus genes 12 (1) 85 - 7 0920-8569 1996
• Nonhuman primate models of measles

  Fumio Kobune; Hiromi Takahashi; Keiji Terao; Tokitada Ohkawa; Yasushi Ami; Yuriko Suzaki; Noriyo Nagata; Hiroko Sakata; Kazuya Yamanouchi; Chieko Kai

  Laboratory Animal Science 46 (3) 315 - 320 0023-6764 1996
• Activation of complement in quails bearing Rous sarcoma virus-induced tumors.

  C Kai; Y Yoshikawa; K Yamanouchi

  The Journal of veterinary medical science 57 (6) 1077 - 80 0916-7250 1995/12
• The feline herpesvirus type 1 ICP4 down-regulates feline immunodeficiency virus long terminal repeat (LTR)-directed gene expression via the C/EBP site in the LTR

  Y Kawaguchi; K Maeda; MR Pecoraro; Y Inoshima; HK Jang; M Kohmoto; K Iwatsuki; Y Ikeda; M Shimojima; Y Tohya; C Kai; T Mikami

  JOURNAL OF VETERINARY MEDICAL SCIENCE JAPAN SOC VET SCI 57 (6) 1129 - 1131 0916-7250 1995/12
• Activation of homologous complement via the alternative complement pathway by quail cells transformed by Rous sarcoma virus.

  C Kai; Y Yoshikawa; H Okada; K Yamanouchi

  The Journal of veterinary medical science 57 (5) 911 - 5 0916-7250 1995/10
• IMMUNOHISTOCHEMICAL ANALYSIS OF THE LYMPHOID ORGANS OF DOGS NATURALLY INFECTED WITH CANINE-DISTEMPER VIRUS

  K IWATSUKI; M OKITA; F OCHIKUBO; T GEMMA; YS SHIN; N MIYASHITA; T MIKAMI; C KAI

  JOURNAL OF COMPARATIVE PATHOLOGY ACADEMIC PRESS (LONDON) LTD 113 (2) 185 - 190 0021-9975 1995/08 [Refereed]
  
• SEROLOGICAL SURVEY OF CANINE-DISTEMPER VIRUS-INFECTION USING ENZYME-LINKED-IMMUNOSORBENT-ASSAY

  T GEMMA; N MIYASHITA; YS SHIN; M OKITA; T MORI; K IWATSUKI; T MIKAMI; C KAI

  JOURNAL OF VETERINARY MEDICAL SCIENCE JAPAN SOC VET SCI 57 (4) 761 - 763 0916-7250 1995/08 [Refereed]
  
• Phylogenetic analysis of the long terminal repeat of feline immunodeficiency viruses from Japan, Argentina and Australia

  H. Yamada; T. Miyazawa; K. Tomonaga; Y. Kawaguchi; K. Maeda; M. C. Castellano; C. Kai; Y. Tohya; T. Mikami

  Archives of Virology SPRINGER-VERLAG WIEN 140 (1) 41 - 52 0304-8608 1995/01
• Immunohistochemical studies of lymphoid tissues of rabbits infected with rinderpest virus.

  M Okita; T Mori; Y S Shin; M Miyasaka; K Yamanouchi; T Mikami; C Kai

  Journal of comparative pathology 112 (1) 41 - 51 0021-9975 1995/01
• Effect of chemical sympathectomy on the neural spread of pseudorabies virus in mice.

  H Takahashi; C Kai; Y Yoshikawa; K Yamanouchi

  Comparative immunology, microbiology and infectious diseases 18 (1) 41 - 54 0147-9571 1995/01
• Immunohistochemical analysis of pseudorabies virus spread through neurons innervating the eyeball

  Hiromi Takahashi; Chieko Kai; Yasuhiro Yoshikawa; Kazuya Yamanouchi

  Comparative Immunology, Microbiology and Infectious Diseases 18 (4) 275 - 281 0147-9571 1995 [Refereed]
  
• STABLE EXPRESSION OF THE CDNA-ENCODING THE FELINE CD8-ALPHA GENE

  MR PECORARO; Y KAWAGUCHI; M OKITA; Y INOSHIMA; Y TOHYA; C KAI; T MIKAMI

  JOURNAL OF VETERINARY MEDICAL SCIENCE JAPAN SOC VET SCI 56 (5) 1001 - 1003 0916-7250 1994/10
• NUCLEOTIDE-SEQUENCE AND CHARACTERIZATION OF THE FELINE HERPESVIRUS TYPE-1 IMMEDIATE-EARLY GENE

  Y KAWAGUCHI; K MAEDA; T MIYAZAWA; M ONO; C KAI; T MIKAMI

  VIROLOGY ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS 204 (1) 430 - 435 0042-6822 1994/10 [Refereed]
  
• COMPARISON OF BIOLOGICAL PROPERTIES OF FELINE IMMUNODEFICIENCY VIRUS ISOLATES USING RECOMBINANT CHIMERIC VIRUSES

  M KOHMOTO; T MIYAZAWA; K TOMONAGA; Y KAWAGUCHI; T MORI; YB TOHYA; C KAI; T MIKAMI

  JOURNAL OF GENERAL VIROLOGY SOC GENERAL MICROBIOLOGY 75 (8) 1935 - 1942 0022-1317 1994/08 [Refereed]
  
• A gD Homologous Gene of Feline Herpesvirus Type I Encodes a Hemagglutinin (gp60)

  Ken Maeda; Yasushi Kawaguchi; Mitsuru Ono; Yasuo Inoshima; Takayuki Miyazawa; Yukinobu Tohya; Chieko Kai; Takeshi Mikami

  Virology ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS 202 (2) 1034 - 1038 0042-6822 1994/08
• Nucleotide Sequence Analysis of Marek’s Disease Virus (MDV) Serotype 2 Homolog of MDV Serotype 1 pp38, an Antigen Associated with Transformed Cells

  Mitsuru Ono; Yasushi Kawaguchi; Ken Maeda; Naohiro Kamiya; Yukinobu Tohya; Chieko Kai; Masahiro Niikura; Takeshi Mikami

  Virology ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS 201 (1) 142 - 146 0042-6822 1994/05
• Protective effect of individual glycoproteins of Newcastle disease virus expressed in insect cells: the fusion protein derived from an avirulent strain had lower protective efficacy

  Kamiya Naohiro; Niikura Masahiro; Ono Mitsuru; Kai Chieko; Matsuura Yoshiharu; Mikami Takeshi

  Virus Research 32 (3) 373 - 379 0168-1702 1994
• Erratum: Expression in baculovirus vector system of the nucleocapsid protein gene of rinderpest virus (J. Virol. Meth. 43 (1993) 159-166)

  H. Kamata; S. Ohkubo; M. Sugiyama; Y. Matsuura; Y. Kamata; K. Tsukiyama-Kohara; K. Imaoka; C. Kai; Y. Yoshikawa; K. Yamanouchi

  Journal of Virological Methods 48 (2-3) 351  0166-0934 1994
• Isolation, sequence and expression of a cDNA encoding the α-chain of the feline CD8

  M. R. Pecoraro; Y. Kawaguchi; T. Miyazawa; J. Norimine; K. Maeda; T. Toyosaki; Y. Tohya; C. Kai; T. Mikami

  Immunology BLACKWELL SCIENCE LTD 81 (1) 127 - 131 0019-2805 1994
• The Molecular Cloning and Sequence of an Open Reading Frame Encoding for Non-Structural Proteins of Feline Calicivirus F4 Strain Isolated in Japan

  Ryoko Oshikamo; Yukinobu Tohya; Yasushi Kawaguchi; Keizo Tomonaga; Ken Maeda; Chieko Kai; Takeshi Mikami

  journal of veterinary medical science JAPAN SOC VET SCI 56 (6) 1093 - 1099 0916-7250 1994
• Optimal conditions for blastogenic response of peripheral blood lymphocytes to T and B cell mitogens in cynomolgus monkeys.

  Wafa Al-Kurdi-Norimine; Fumiko Ochikubo; Yasushi Ami; Kazuya Yamanouchi; Chieko Kai

  American journal of primatology 33 (4) 301 - 308 1994
• Mechanism of pruritus and peracute death in mice induced by pseudorabies virus (PRV) infection.

  H Takahashi; Y Yoshikawa; C Kai; K Yamanouchi

  The Journal of veterinary medical science 55 (6) 913 - 20 0916-7250 1993/12
• Antigenic analysis of feline calicivirus capsid precursor protein and its deleted polypeptides produced in a mammalian cDNA expression system

  Shin Yeon-Sil; Tohya Yukinobu; Oshikamo Ryoko; Kawaguchi Yasushi; Tomonaga Keizo; Miyazawa Takayuki; Kai Chieko; Mikami Takeshi

  Virus Research 30 (1) 17 - 26 0168-1702 1993/10 [Refereed]
  
• ELECTROENCEPHALOGRAM AND EVOKED-POTENTIALS IN THE PRIMATE MODEL OF VIRAL ENCEPHALITIS

  F OCHIKUBO; T NAGATA; Y YOSHIKAWA; Y MATSUBARA; C KAI; Y YAMANOUCHI

  ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY ELSEVIER SCI IRELAND LTD 88 (5) 397 - 407 0013-4694 1993/09 [Refereed]
  
• Identification and nucleotide sequence of a gene in feline herpesvirus type 1 homologous to the herpes simplex virus gene encoding the glycoprotein H

  K. Maeda; Y. Kawaguchi; N. Kamiya; M. Ono; Y. Tohya; C. Kai; T. Mikami

  Archives of Virology SPRINGER-VERLAG WIEN 132 (1-2) 183 - 191 0304-8608 1993/03
• LOCALIZATION OF THE VIRAL-ANTIGEN OF FELINE IMMUNODEFICIENCY VIRUS IN THE LYMPH-NODES OF CATS AT THE EARLY-STAGE OF INFECTION

  T TOYOSAKI; T MIYAZAWA; T FURUYA; K TOMONAGA; YS SHIN; M OKITA; Y KAWAGUCHI; C KAI; S MORI; T MIKAMI

  ARCHIVES OF VIROLOGY SPRINGER-VERLAG WIEN 131 (3-4) 335 - 347 0304-8608 1993 [Refereed]
  
• Electroencephalogram and evoked potentials in the primate model of viral encephalitis

  F. Ochikubo; T. Nagata; Y. Yoshikawa; Y. Matsubara; C. Kai; Y. Yamanouchi

  Electroencephalography and Clinical Neurophysiology/ Evoked Potentials 88 (5) 397 - 407 0168-5597 1993 [Refereed]
  
• Use of B95a Cells for Isolation of Canine Distemper Virus from Clinical Cases.

  KAI Chieko; OCHIKUBO Fumiko; OKITA Masatsugu; IINUMA Tetsuo; MIKAMI Takeshi; KOBUNE Fumio; YAMANOUCHI Kazuya

  Journal of Veterinary Medical Science JAPANESE SOCIETY OF VETERINARY SCIENCE 55 (6) 1067 - 1070 0916-7250 1993 [Refereed]
  
• Comparison of the Pathogenicity of Rinderpest Virus in Different Strains of Rabbits.

  OKITA Masatsugu; OCHIKUBO Fumiko; KAMATA Yasue; KAMATA Hiroshi; YAMANOUCHI Kazuya; KAI Chieko

  Journal of Veterinary Medical Science JAPANESE SOCIETY OF VETERINARY SCIENCE 55 (6) 951 - 954 0916-7250 1993 [Refereed]
  
• THE RESTRICTION ENDONUCLEASE MAP OF MAREKS-DISEASE VIRUS (MDV) SEROTYPE-2 AND COLLINEAR RELATIONSHIP AMONG 3 SEROTYPES OF MDV

  M ONO; R KATSURAGIIWANAGA; T KITAZAWA; N KAMIYA; T HORIMOTO; M NIIKURA; C KAI; K HIRAI; T MIKAMI

  VIROLOGY ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS 191 (1) 459 - 463 0042-6822 1992/11 [Refereed]
  
• IDENTIFICATION OF A FELINE IMMUNODEFICIENCY VIRUS GENE WHICH IS ESSENTIAL FOR CELL-FREE VIRUS INFECTIVITY

  K TOMONAGA; J NORIMINE; YS SHIN; M FUKASAWA; T MIYAZAWA; A ADACHI; T TOYOSAKI; Y KAWAGUCHI; C KAI; T MIKAMI

  JOURNAL OF VIROLOGY AMER SOC MICROBIOLOGY 66 (10) 6181 - 6185 0022-538X 1992/10 [Refereed]
  
• Sequences within the feline immunodeficiency virus long terminal repeat that regulate gene expression and respond to activation by feline herpesvirus type 1

  Yasushi Kawaguchi; Junzo Norimine; Takayuki Miyazawa; Chieko Kai; Takeshi Mikami

  Virology 190 (1) 465 - 468 0042-6822 1992/09 [Refereed]
  
• Immunohistochemical and histopathological study of experimental rabies infection in mice.

  T A Sinchaisri; T Nagata; Y Yoshikawa; C Kai; K Yamanouchi

  The Journal of veterinary medical science 54 (3) 409 - 16 0916-7250 1992/06
• Identification and nucleotide sequence of a gene in feline herpesvirus type 1 homologous to the herpes simplex virus gene encoding the glycoprotein B

  K. Maeda; T. Horimoto; J. Norimine; Y. Kawaguchi; K. Tomonaga; M. Niikura; C. Kai; E. Takahashi; T. Mikami

  Archives of Virology SPRINGER-VERLAG WIEN 127 (1-4) 387 - 397 0304-8608 1992/03
• Heterogeneity of feline herpesvirus type 1 strains

  T. Horimoto; J. A. Limcumpao; X. Xuan; M. Ono; K. Maeda; Y. Kawaguchi; C. Kai; E. Takahashi; T. Mikami

  Archives of Virology SPRINGER-VERLAG WIEN 126 (1-4) 283 - 292 0304-8608 1992/03
• Replicative difference in early-passage feline brain cells among feline immunodeficiency virus isolates

  Y. Kawaguchi; K. Maeda; Y. Tohya; T. Furuya; T. Miyazawa; T. Horimoto; J. Norimine; C. Kai; T. Mikami

  Archives of Virology SPRINGER-VERLAG WIEN 125 (1-4) 347 - 354 0304-8608 1992/03
• FURTHER CHARACTERIZATION OF A FELINE T-LYMPHOBLASTOID CELL-LINE (MYA-1 CELLS) HIGHLY SENSITIVE FOR FELINE IMMUNODEFICIENCY VIRUS

  T MIYAZAWA; T TOYOSAKI; K TOMONAGA; J NORIMINE; K OHNO; A HASEGAWA; C KAI; T MIKAMI

  JOURNAL OF VETERINARY MEDICAL SCIENCE JAPAN SOC VET SCI 54 (1) 173 - 175 0916-7250 1992/02 [Refereed]
  
• A CDNA-ENCODING FELINE CD4 HAS A UNIQUE REPEAT SEQUENCE DOWNSTREAM OF THE V-LIKE REGION

  J NORIMINE; T MIYAZAWA; Y KAWAGUCHI; Y TOHYA; C KAI; T MIKAMI

  IMMUNOLOGY BLACKWELL SCIENCE LTD 75 (1) 74 - 79 0019-2805 1992/01 [Refereed]
  
• Comparison of the Viral Promoter Activities in Feline Cell Lines (CRFK and fcwf-4 Cells)

  Junzo Norimine; Takayuki Miyazawa; Yasushi Kawaguchi; Masahiro Niikura; Chieko Kai; Takeshi Mikami

  Journal of Veterinary Medical Science 54 (1) 189 - 191 0916-7250 1992 [Refereed]
  
• Effect of the EBNA-2 gene on the surface antigen phenotype of transfected EBV-negative B-lymphoma lines.

  P Aman; M Rowe; C Kai; J Finke; L Rymo; E Klein; G Klein

  International journal of cancer 45 (1) 77 - 82 0020-7136 1990/01
• Activation of B lymphocytes with human serum-treated zymosan.

  C Kai; R Szigeti; P Aman; E Klein

  Cellular immunology 116 (2) 467 - 74 0008-8749 1988/10
• Elevated NK sensitivity of Raji cells carrying acceptor-bound C3 fragments.

  C Kai; G Sármay; O Ramos; E Yefenof; E Klein

  Cellular immunology 113 (2) 227 - 34 0008-8749 1988/05
• The elevated natural killer sensitivity of targets carrying surface-attached C3 fragments require the availability of the iC3b receptor (CR3) on the effectors.

  O F Ramos; C Kai; E Yefenof; E Klein

  Journal of immunology (Baltimore, Md. : 1950) 140 (4) 1239 - 43 0022-1767 1988/02
• EXPRESSION OF CR2 (C3d RECEPTOR) ON THE CELL MEMBRANES OF ADULT T CELL LEUKEMIA

  Chieko Kai; Noriko Okada; Hidechika Okada

  Japanese Journal of Cancer Research 79 (7) 805 - 808 1349-7006 1988
• Alternative pathway of complement activation by stimulated T lymphocytes. I. Binding of C3 fragments.

  G Sármay; O F Ramos; E Klein; C Kai; J Gergely

  European journal of immunology 17 (7) 969 - 74 0014-2980 1987/07
• Effect of complement depletion by cobra venom factor on fowlpox virus infection in chickens and chicken embryos.

  H Ohta; Y Yoshikawa; C Kai; K Yamanouchi; H Taniguchi; K Komine; Y Ishijima; H Okada

  Journal of virology 57 (2) 670 - 3 0022-538X 1986/02
• Neurovirulence in mice of neural cell-adapted canine distemper virus.

  Y Morikawa; Y Matsubara; Y Yoshikawa; C Kai; K Yamanouchi

  Microbiology and immunology 30 (3) 225 - 36 0385-5600 1986
• Ontogeny of the third component of complement of Japanese quails.

  C Kai; Y Yoshikawa; K Yamanouchi; H Okada; S Morikawa

  Immunology 54 (3) 463 - 70 0019-2805 1985/03
• Lysis of horse red blood cells mediated by antibody-independent activation of the alternative pathway of chicken complement.

  H Ohta; Y Yoshikawa; C Kai; K Yamanouchi; H Okada

  Immunology 52 (3) 437 - 44 0019-2805 1984/07
• Activation of chicken alternative complement pathway by fowlpox virus-infected cells.

  H Ohta; C Kai; Y Yoshikawa; K Yamanouchi

  Infection and immunity 42 (2) 721 - 7 0019-9567 1983/11
• Isolation and identification of the third component of complement of Japanese quails.

  C Kai; Y Yoshikawa; K Yamanouchi; H Okada

  Journal of immunology (Baltimore, Md. : 1950) 130 (6) 2814 - 20 0022-1767 1983/06

Conference Activities & Talks

• An oncolytic recombinant measles virus, rMV-SLAMblind, is a promising candidate for cancer therapy.

  Kai C; Fujiyuki T; Moritoh K; Takahashi S; Nakano K; Nagamura F; Sato H; Yoneda M

  第1回日本ウイルス療法学会学術集会 インターナショナルシンポジウム Basic and clinical development of new oncolytic viruses  2023/11
• 乳癌に対する腫瘍溶解性麻疹ウイルス療法の開発

  甲斐知惠子; 藤幸知子; 森藤可南子; 高橋俊二; 仲野兼司; 長村文孝; 佐藤宏樹; 米田美佐子

  第31回日本乳癌学会学術総会  2023/06
• ウイルスベクターの利用による医療法開発

  甲斐知惠子

  第２３回医薬品等ウイルス安全性シンポジウム （日本医薬品等ウイルス安全性研究会）  2023/03
• One Health, One World-Toward the formation of the first hub of One Health, One world

  甲斐知惠子

  The 1st International Symposium on One Health, One World
• ウイルスは役に立つー新しいがんの治療法ー

  甲斐知惠子

  取手市市民大学特別講座  2022/11
• A recombinant measles virus, rMV-SLAMblind is a promising candidate for a novel oncolytic cancer therapy

  Kai C

  14th International Oncolytic Virotherapy Conference (IOVC 2022)
• がん治療用遺伝子組換え麻疹ウイルスの臨床開発

  甲斐知惠子; 藤幸知子; 森藤可南子; 高橋俊二; 仲野兼司; 長村文孝; 古川洋一; 佐藤宏樹; 米田美佐子

  第81回日本癌学会  2022/10
• コウモリが保有する病原体を知る

  甲斐知惠子; 米田美佐子

  第165回日本獣医学会学術集会 微生物分科会シンポジウム  2022/09
• 新興ウイルス感染症との闘いーワンヘルス・ワンワールドー

  甲斐知惠子

  東京大学生命科学シンポジウム  2022/06
• 医療工学研究会の紹介及び癌治療用麻疹ウイルス開発の概要

  甲斐知惠子

  医療工学研究会2021年度公開ワークショップ  2022/03
• One Health, One Worldの由来-人獣共通感染症研究

  甲斐知惠子

  第１回OHOW公開講演会  2022/02
• 腫瘍溶解性麻疹ウイルスによる新たな治療法の開発

  甲斐知惠子; 藤幸知子; 森藤可南子; 長村文孝; 古川洋一; 高橋俊二; 米田美佐子

  第８０回日本癌学会、シンポジウム「がん研究における女性研究者」  2021/09

MISC

• FOS transcriptionally regulates PVRL4, a receptor for measles virus.

  七宮知之; 高根希世子; 山口貴世志; 池上恒雄; 藤幸知子; 米田美佐子; 甲斐知惠子; 古川洋一  日本癌学会学術総会抄録集(Web)  81st-  2022
• One Health, One World-A global approach on the future path of infectious disease research

  甲斐知惠子; 米田美佐子  実験医学  39-  (2)  2021
• Applicability of a recombinant SLAM-blind measles virus to breast cancer treatment

  Chieko Kai; Tomoko Fujiyuki; Hiroki Sato; Yataro Daigo; Misako Yoneda  CANCER SCIENCE  109-  274  -274  2018/12  [Refereed]
  
• Potential applicable range of oncolytic virotherapy with a recombinant measles virus in dogs

  Tomoko Fujiyuki; Koichiro Shoji; Keigo Iizuka; Yu Horikirizono; Hiroki Sato; Kazushi Asano; Misako Yoneda; Chieko Kai  CANCER SCIENCE  109-  1037  -1037  2018/12
• Elucidation of transcriptional regulation mechanism of PVRL4, a receptor for oncolytic measles virus

  Saku Akari; Yamaguchi Kiyoshi; Ikenoue Tsuneo; Fujiyuki Tomoko; Yoneda Misako; Hata Hiroko; Oyama Masaaki; Kai Chieko; Furukawa Yoichi  CANCER SCIENCE  109-  979  2018/01  [Refereed]
  
• An oncolytic recombinant measles virus is a candidate of a novel therapeutic agent for triple negative breast cancer

  T. Fujiyuki; Y. Amagai; K. Shoji; A. Sugai; M. Awano; H. Sato; M. Yoneda; C. Kai  HUMAN GENE THERAPY  28-  (12)  A5  -A5  2017/12
• Development of oncolytic measles virus, rMV-SLAMblind

  C. Kai; T. Fujiyuki; K. Shoji; H. Sato; M. Yoneda  HUMAN GENE THERAPY  28-  (12)  A25  -A25  2017/12
• A novel strategy of oncotherapy using a recombinant oncolytic measles virus

  Chieko Kai; Takaaki Sugiyama; Tomoko Fujiyuki; Misako Yoneda  INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE  34-  (Supplement 1)  S131  -S131  2014  [Invited]
  
• 新世界ザルの副腎に関する形態学的研究

  尾崎 早百合; 日下部 健; 加納 聖; 服部 正策; 倉石 武; 吉澤 緑; 甲斐 知恵子; 木曾 康郎  日本獣医学会学術集会講演要旨集  156回-  191  -191  2013/08
• 神経由来細胞樹立麻疹ウイルス持続感染株の樹立と性状

  木曽有里; 佐藤宏樹; 新井哲郎; 藤幸知子; 土井知光; 米田美佐子; 甲斐知恵子  日本ウイルス学会学術集会プログラム・抄録集  61st-  2013
• 新世界ザル雌性生殖器の微細構造

  高畠 大樹; 日下部 健; 加納 聖; 服部 正策; 倉石 武; 吉澤 緑; 甲斐 知恵子; 木曾 康郎  日本獣医学会学術集会講演要旨集  154回-  178  -178  2012/08
• Henipavirus infections - An Expanding Zoonosis from fruit Bats

  Chieko Kai; Misako Yoneda  Journal of Disaster Research  6-  (4)  390  -397  2011
• イヌジステンパーウイルスP蛋白質に対するモノクローナル抗体の性状解析

  菅井亮宏; 郡山尚紀; 佐藤宏樹; 米田美佐子; 甲斐知恵子  日本獣医学会学術集会講演要旨集  148th-  203  -203  2009
• デリバリーベクター開発にむけたイヌSOD1組換えCDVの作製

  武藤由里; 郡山尚紀; 三浦竜一; 米田美佐子; 甲斐知恵子  日本獣医学会学術集会講演要旨集  144th-  88  -88  2007
• マウス脳内におけるアトラクチンとプリオンの関連

  三浦竜一; 郡山尚紀; 武藤由里; 甲斐知恵子  日本獣医学会学術集会講演要旨集  137th-  181  -181  2004
• リーシュマニア抗原発現組換えイヌジステンパーウイルスの作出

  郡山尚紀; 三浦竜一; 小原恭子; 甲斐知恵子  日本獣医学会学術集会講演要旨集  136th-  131  -131  2003
• イヌジステンパーウイルスの遺伝子の並び順の重要性

  佐藤宏樹; 郡山尚紀; 三浦竜一; 小原恭子; 甲斐知恵子  日本獣医学会学術集会講演要旨集  136th-  131  -131  2003
• EGFP-CDVを用いたイヌ海馬におけるウイルス動態の観察

  郡山尚紀; 藤田賢太郎; 佐藤宏樹; 三浦竜一; 小原恭子; 甲斐知恵子  日本獣医学会学術集会講演要旨集  135th-  126  -126  2003
• バキュロウイルス発現系による牛疫ウイルスP蛋白の作製

  金井もえ子; 米田美佐子; 藤田賢太郎; 郡山尚紀; 甲斐知恵子  日本獣医学会学術集会講演要旨集  135th-  125  -125  2003
• イヌジステンパーウイルスP蛋白に対するモノクローナル抗体の作製

  郡山尚紀; 米田美佐子; 佐藤宏樹; 三浦竜一; 小原恭子; 甲斐知恵子  日本獣医学会学術集会講演要旨集  134th-  137  -137  2002
• イヌジステンパーウイルスの非構造蛋白,C,Vのウイルス増殖への関与

  郡山尚紀; 清水房子; 米田美佐子; 佐藤宏樹; 三浦竜一; 相良洋; 小原恭子; 甲斐知恵子  日本獣医学会学術集会講演要旨集  133rd-  108  -108  2002
• CDV新型株の犬における感染防御試験

  竹中亜希子; 米田美佐子; 上間匡; 郡山尚紀; 甲斐知恵子  日本獣医学会学術集会講演要旨集  134th-  138  -138  2002
• センダイウイルス発現イヌか粒球マクロファージコロニー刺激因子(GM-CSF)のin vivoでの効果

  遠藤泰之; 三浦竜一; 平間郷子; 西俊哉; 上間匡; 郡山尚紀; 江島美穂; 星美穂; 甲斐知恵子  日本獣医学会学術集会講演要旨集  132nd-  151  -151  2001
• 麻疹サル感染実験系の確立と応用 : 胸腺感染症としての麻疹

  小船 富美夫; 網 康至; 永田 典代; 須崎 百合子; 高橋 浩美; 甲斐 知恵子; 山内 一也  臨床とウイルス  25-  (2)  S4  1997/05
• Characterization of the Feline Herpesvirus Type 1 Immediate Early Gene Expression.

  KAWAGUCHI Yasushi; MAEDA Ken; ONO Mitsuru; YOKOYAMA Naoaki; TSUBOTA Kenjiro; FUJITA Kentaro; TOHYA Yukinobu; KAI Chieko; MIKAMI Takeshi  Journal of Veterinary Medical Science  58-  (8)  715  -721  1996
• EXPRESSION IN BACULOVIRUS VECTOR SYSTEM OF THE NUCLEOCAPSID PROTEIN GENE OF RINDERPEST VIRUS

  H KAMATA; S OHKUBO; M SUGIYAMA; Y MATSUURA; Y KAMATA; K TSUKIYAMAKOHARA; K IMAOKA; C KAI; Y YOSHIKAWA; K YAMANOUCHI  JOURNAL OF VIROLOGICAL METHODS  43-  (2)  159  -166  1993/07

Research Grants & Projects

• ⿇疹ウイルスベクターを⽤いたニパウイルス感染症ワクチンの開発

  日本医療研究開発機構：ワクチン・新規モダリティ研究開発事業

  Date (from‐to) : 2023/02 -2027/03
• 遺伝子組換え麻疹ウイルスを用いた抗がんウイルス療法の臨床研究

  日本医療研究開発機構：革新的がん医療実用化研究事業

  Date (from‐to) : 2020/04 -2023/03
• Development of a Nipah measles vector vaccine (MV-NIV) to be used in outbreaks situation in children and adults exposed population

  Coalition for Epidemic Preparedness Innovations (CEPI)：

  Date (from‐to) : 2019/02 -2023/03
• 遺伝子組換え麻疹ウイルスを用いた癌治療法の開発

  AMED：革新的がん医療実用化研究事業

  Date (from‐to) : 2017/04 -2020/03
• Comprehensive analysis of acetylation network post morbillivirus infection using novel analysis method

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (A)

  Date (from‐to) : 2016/04 -2020/03 

  Author : Kai Chieko
• Molecular basis underlying anti-tumor activity of an oncolytic measles virus

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B)

  Date (from‐to) : 2016/04 -2019/03 

  Author : Fujiyuki Tomoko; KAI Chieko; YONEDA Misako
• Establishment of humanized mice as a small animal model for measles virus infection

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)

  Date (from‐to) : 2016/04 -2019/03 

  Author : NAKANISHI Tomoko; KAI Chieko
• Development of measles virus vector-based vaccine against highly pathogenic avian influenza virus

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B)

  Date (from‐to) : 2014/04 -2017/03 

  Author : Fujiyuki Tomoko; KAI Chieko; YONEDA Misako; KOHARA Michinori; KIDA Hiroshi; HATTORI Shosaku
• 癌治療用組換え麻疹ウイルスの開発

  AMED：革新的がん医療実用化研究事業

  Date (from‐to) : 2015/04 -2016/04
• Analysis of host cellular transcriptional network induced by mononegavirus infection.

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (S)

  Date (from‐to) : 2010/04 -2016/03 

  Author : KAI CHIEKO; YONEDA MISAKO; SATO HIROKI; HAYASHIZAKI YOSHIHIDE
• モービリウイルスの感染宿主細胞応答制御機構の解明

  日本学術振興会：科学研究費助成事業 基盤研究(A)

  Date (from‐to) : 2010 -2010 

  Author : 甲斐 知恵子
• ニパウイルスの病原性発現機構の解析

  日本学術振興会：科学研究費助成事業 特定領域研究

  Date (from‐to) : 2009 -2010 

  Author : 甲斐 知恵子; 米田 美佐子
• Analysis of factors implicated in pathogenicity of mononegaviruses and development of a vaccine candidate.

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (A)

  Date (from‐to) : 2007 -2009 

  Author : KAI Chieko; NAKAYAMA Hiroyuki; YONEDA Misako; SATOU Hiroki
• Reverse geneticsを用いたニパウイルスの病原性発現機構の解析

  日本学術振興会：科学研究費助成事業 特定領域研究

  Date (from‐to) : 2007 -2008 

  Author : 甲斐 知恵子; 米田 美佐子
• Establishment and analysis of measles virus-susceptible transgenic mice.

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)

  Date (from‐to) : 2004 -2005 

  Author : MIURA Ryuichi; KAI Chieko; KOHARA Kyoko
• The development of animal model using squirrel monkey (Saimiri sciureus boliviensis) for human malaria infection

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)

  Date (from‐to) : 2003 -2004 

  Author : HATTORI Shosaku; KAI Chieko
• Development of the new vaccine and a delivery vector by the recombination Morbilli virus.

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B)

  Date (from‐to) : 2002 -2003 

  Author : KOHARA Kyoko; KAI Chieko
• Analysis of the species specific pathogenicity of morbillivirus by reverse genetics.

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (A)

  Date (from‐to) : 2000 -2003 

  Author : KAI Chieko; TUJIMOTO Hajime; NAKAYAMA Hiroyuki; MIURA Ryuichi; KOHARA Kyoko; YAMANOUCHI Kazuya
• 新組み換え技術を用いたがん治療用麻疹ウイルスベクターの開発

  日本学術振興会：科学研究費助成事業 特定領域研究

  Date (from‐to) : 2002 -2002 

  Author : 小原 恭子; 甲斐 知恵子
• 体細胞クローン動物の誕生によって変貌した研究フロンティアの推進

  日本学術振興会：科学研究費助成事業 基盤研究(C)

  Date (from‐to) : 2002 -2002 

  Author : 佐藤 英明; 西森 克彦; 甲斐 知恵子; 角田 幸雄; 佐々田 比呂志; 眞鍋 昇
• モノネガウイルスのM蛋白欠損による新型ウイルスワクチン/ベクターの開発

  日本学術振興会：科学研究費助成事業 萌芽的研究

  Date (from‐to) : 2001 -2001 

  Author : 甲斐 知恵子; 三浦 竜一
• C型肝炎ウイルスのツパイ感染実験モデル系の開発

  日本学術振興会：科学研究費助成事業 萌芽的研究

  Date (from‐to) : 2001 -2001 

  Author : 小原 恭子; 甲斐 知恵子
• 遺伝的発症モデル動物を用いた海綿状脳症形成機構の解析

  日本学術振興会：科学研究費助成事業 特定領域研究(A)

  Date (from‐to) : 2000 -2001 

  Author : 三浦 竜一; 甲斐 知恵子
• Development of Immune Induction System by Using The Novel Virus Vectors of Cytokines

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B)

  Date (from‐to) : 1999 -2001 

  Author : KAI Chieko; KOHARA Kyoko; NAKAYAMA Hiroyuki; TSUJIMOTO Hajime; ENDO Yasuyuki; MIURA Ryuichi
• 動物ウイルスによる宿主細胞の制圧機構の解明

  生物系特定産業技術研究推進機構：新技術・新分野創出のための基礎研究推進事業

  Date (from‐to) : 1997 -2001
• ウイルスの感染・増殖における宿主細胞の細胞骨格系の役割

  日本学術振興会：科学研究費助成事業 萌芽的研究

  Date (from‐to) : 1999 -1999 

  Author : 甲斐 知恵子; 中山 裕之; 尾崎 博
• ニワトリ補体蛋白の基礎性状の解析

  日本学術振興会：科学研究費助成事業

  Date (from‐to) : 1984 -1984 

  Author : 甲斐 知恵子

Committee Membership

• 2009/01 -2011   CLAC-OSC/BASE