Takahashi Senji

Researcher Information

Affiliation

Department of Biosciences Professor

URL

https://jglobal.jst.go.jp/detail?JGLOBAL_ID=202001005319568032

Research funding number

• 00236291

J-Global ID

• 202001005319568032

Research Interests

• bioactive compounds   natural products chemistry   

Research Areas

• Life sciences / Bioorganic chemistry

Academic & Professional Experience

• 2020/04 - Today  Teikyo UniversityFaculty of Science and Engineering Department of Biosciences
• 2010/04 - 2020/03  Teikyo UniversityFaculty of Science and Engineering Department of Biosciences
• 2005/04 - 2010/03  Teikyo UniversityFaculty of Science and Engineering Department of Biosciences
• 1991/04 - 2005/03  Teikyo UniversityFaculty of Science and Engineering Department of Biosciences

Education

• 1985/04 - 1987/03  Tokyo University of Science  Graduate School of Science
• 1981/04 - 1985/03  Tokyo University of Science

Research Activity Information

Published Papers

• A new metabolite, mannogeranylnerol, specifically produced at body temperature by Schizophyllum commune, a causative fungus of human mycosis.

  Shing Yiu Tam; Kenichi Uchida; Hirofumi Enomoto; Senji Takahashi; Koichi Makimura; Shohei Sakuda

  The Journal of antibiotics 75 (4) 243 - 246 2022/04 [Refereed]
  
• Light dependent accumulation of beta-carotene enhances photo-acclimation of Euglena gracilis

  Yuri Tanno; Shota Kato; Senji Takahashi; Shun Tamaki; Shinichi Takaichi; Yutaka Kodama; Kintake Sonoike; Tomoko Shinomura

  JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY ELSEVIER SCIENCE SA 209 1011-1344 2020/08 [Refereed]
  
• Distribution of Flavan-3-ol Species in Ripe Strawberry Fruit Revealed by Matrix-Assisted Laser Desorption/Ionization-Mass Spectrometry Imaging

  Hirofumi Enomoto; Senji Takahashi; Shiro Takeda; Hajime Hatta

  Molecules MDPI AG 25 (1) 103 - 103 2020 [Refereed]
  
• Identification and functional analysis of the geranylgeranyl pyrophosphate synthase gene (crtE) and phytoene synthase gene (crtB) for carotenoid biosynthesis in Euglena gracilis

  Shota Kato; Shinichi Takaichi; Takahiro Ishikawa; Masashi Asahina; Senji Takahashi; Tomoko Shinomura

  BMC Plant Biology Springer Science and Business Media LLC 16 (1) 1471-2229 2016/12 [Refereed]
  
• Changes in polyamine levels in Xenopus early embryogenesis.

  K. Shiokawa; T. Mishina; H. Yoshida; J. Takai; K. Tsuboshima; T. Soutome; T. Terui; H. Abe; S. Sakurai; S. Takahashi; K. Tashiro; K. Igarashi

  Trends Develop. Biol. 7 25 - 31 2013 [Refereed]
  
• Polyamines added to the culture medium of Xenopus fertilized eggs induce massive cell dissociation at the blastula stage by interfering with Ca2+-dependent cell adhesion.

  K. Shiokawa; T. Kondo; S. Takahashi; K. Igarashi

  Amino Acids. SPRINGER WIEN 45 (3) 571 - 572 0939-4451 2013 [Refereed]
  
• Gene Expression in Pre-MBT Embryos and Activation of Maternally-Inherited Program of Apoptosis to be Executed at around MBT as a Fail-Safe Mechanism inXenopusEarly Embryogenesis

  Koichiro Shiokawa; Mai Aso; Takeshi Kondo; Hiroaki Uchiyama; Shinsaku Kuroyanagi; Jun-Ichi Takai; Senji Takahashi Masayuki Kajitani; Chikara Kaito; Kazuhisa Sekimizu; Eiji Takayama; Kazuei Igarashi; Hiroshi Hara

  Gene Regulation and Systems Biology SAGE Publications 2 213 - 231 1177-6250 2008/01 [Refereed]
  
• Byelyankacin: A Novel Melanogenesis Inhibitor Produced by Enterobacter sp. B20

  Senji Takahashi; Hiroki Iwai; Kunio Kosaka; Toshitsugu Miyazaki; Yuko Osanai; Nakako Arao; Kouichi Tanaka; Koji Nagai; Akira Nakagawa

  The Journal of Antibiotics Springer Science and Business Media LLC 60 (11) 717 - 720 0021-8820 2007 [Refereed]
  
• Biosynthesis of Quinolactacin A, a TNF Production Inhibitor

  Tatsuya Sasaki; Senji Takahashi; Kenichi Uchida; Shinji Funayama; Masatsune Kainosho; Akira Nakagawa

  The Journal of Antibiotics Springer Science and Business Media LLC 59 (7) 418 - 427 0021-8820 2006 [Refereed]
  
• Screening of Actinomycetes with antinematodal properties.

  KAZUYOSHI CHUBACHI; MAKOTO FURUKAWA; SHIGEAKI FUKUDA; SENJI TAKAHASHI; TADASHI YANAGISAWA; HIDEO ITAGAWA; TERUO SHIMIZU; AKIRA NAKAGAWA

  Biocontrol Science The Society for Antibacterial and Antifungal Agents, Japan 7 (1) 49 - 54 1342-4815 2002 [Refereed]
  
• Adxanthromycins A and B, New Inhibitors of ICAM-1/LFA-1 Mediated Cell Adhesion Molecule from Streptomyces sp. NA-148. I. Taxonomy, Production, Isolation and Biological Activities.

  TAKAYUKI NAKANO; TSUKASA KOIWA; SENJI TAKAHASHI; AKIRA NAKAGAWA

  The Journal of Antibiotics Japan Antibiotics Research Association 53 (1) 12 - 18 0021-8820 2000 [Refereed]
  
• Adxanthromycins A and B, New Inhibitors of ICAM-1/LFA-1 Mediated Cell Adhesion Molecule from Streptomyces sp. NA-148. II. Physico-chemical Properties and Structure Elucidation.

  SENJI TAKAHASHI; TAKAYUKI NAKANO; TSUKASA KOIWA; TOSHIRO NOSHITA; SHINJI FUNAYAMA; HIROYUKI KOSHINO; AKIRA NAKAGAWA

  The Journal of Antibiotics Japan Antibiotics Research Association 53 (2) 163 - 170 0021-8820 2000 [Refereed]
  
• Quinolactacins A, B and C. Novel Quinolone Compounds from Penicillium sp. EPF-6. I. Taxonomy, Production, Isolation and Biological Properties.

  NORIHIRO KAKINUMA; HIROKI IWAI; SENJI TAKAHASHI; KUNIKATSU HAMANO; TADASHI YANAGISAWA; KOJI NAGAI; KOICHI TANAKA; KENICHI SUZUKI; FUMIKO KIRIKAE; TERUO KIRIKAE; AKIRA NAKAGAWA

  The Journal of Antibiotics Japan Antibiotics Research Association 53 (11) 1247 - 1251 0021-8820 2000 [Refereed]
  
• Quinolactacins A, B and C. Novel Quinolone Compounds from Penicillium sp. EPF-6. II. Physico-chemical Properties and Structure Elucidation.

  SENJI TAKAHASHI; NORIHIRO KAKINUMA; HIROKI IWAI; TADASHI YANAGISAWA; KOJI NAGAI; KENICHI SUZUKI; TATSUHIRO TOKUNAGA; AKIRA NAKAGAWA

  The Journal of Antibiotics Japan Antibiotics Research Association 53 (11) 1252 - 1256 0021-8820 2000 [Refereed]
  
• Inhibitory Effect of Antimicrobial Agents on Alginate Production in Pseudomonas aeruginosa.

  TAKAYUKI HOSOYAMA; TAKEHIRO YUGE; SENJI TAKAHASHI; TOMOO SUZUKI; TOYOJI OKUBO; SHIZUKO IYOBE; AKIRA NAKAGAWA

  The Journal of Antibiotics Japan Antibiotics Research Association 52 (1) 65 - 67 0021-8820 1999 [Refereed]
  
• Adxanthromycin: A New Inhibitor of ICAM-1/LFA-1 Mediated Cell Adhesion from Streptomyces sp. NA-148.

  TSUKASA KOIWA; TAKAYUKI NAKANO; SENJI TAKAHASHI; HIROYUKI KOSHINO; MIKA YAMAZAKI; TOHRU TAKASHI; AKIRA NAKAGAWA

  The Journal of Antibiotics Japan Antibiotics Research Association 52 (2) 198 - 200 0021-8820 1999 [Refereed]
  
• Control of Root-knot Nematodes by Streptomyces: Screening of Root-knot Nematode-controlling Actinomycetes and Evaluation of Their Usefulness in a Pot Test

  Kazuyoshi CHUBACHI; Makoto FURUKAWA; Shigeaki FUKUDA; Senji TAKAHASHI; Shoji MATSUMURA; Hideo ITAGAWA; Teruo SHIMIZU; Akira NAKAGAWA

  Nematological Research (Japanese Journal of Nematology) The Japanese Nematological Society 29 (2) 42 - 45 0919-6765 1999 [Refereed]
  
• Pyridovericin and Pyridomacrolidin: Novel Metabolites from Entomopathogenic Fungi, Beauveria bassiana.

  SENJI TAKAHASHI; NORIHIRO KAKINUMA; KENICHI UCHIDA; RYUJU HASHIMOTO; TADASHI YANAGISAWA; AKIRA NAKAGAWA

  The Journal of Antibiotics Japan Antibiotics Research Association 51 (6) 596 - 598 0021-8820 1998 [Refereed]
  
• The Structures of Pyridovericin and Pyridomacrolidin, New Metabolites from the Entomopathogenic Fungus, Beauveria bassiana.

  SENJI TAKAHASHI; KENICHI UCHIDA; NORIHIRO KAKINUMA; RYUJU HASHIMOTO; TADASHI YANAGISAWA; AKIRA NAKAGAWA

  The Journal of Antibiotics Japan Antibiotics Research Association 51 (11) 1051 - 1054 0021-8820 1998 [Refereed]
  
• A Search for Pseudomonas Alginate Biosynthesis Inhibitors from Microbial Metabolites

  AKIRA NAKAGAWA; TAKAYUKI HOSOYAMA; KAZUYOSHI CHUBACHI; SENJI TAKAHASHI; TOYOJI OHKUBO; SHIZUKO IYOBE

  The Journal of Antibiotics Japan Antibiotics Research Association 50 (3) 286 - 288 0021-8820 1997 [Refereed]
  
• Melanoxazal, New Melanin Biosynthesis Inhibitor Discovered by Using the Larval Haemolymph of the Silkworm, Bombyx mori. Production, Isolation, Structural Elucidation, and Biological Properties.

  SENJI TAKAHASHI; RYUJU HASHIMOTO; KUNIKATSU HAMANO; TOMOO SUZUKI; AKIRA NAKAGAWA

  The Journal of Antibiotics Japan Antibiotics Research Association 49 (6) 513 - 518 0021-8820 1996 [Refereed]
  
• Biosynthesis of Lactacystin.

  SENJI TAKAHASHI; KENICHI UCHIDA; AKIRA NAKAGAWA; YOKO MIYAKE; MASATSUNE KAINOSHO; KEIICHI MATSUZAKI; SATOSHI OMURA

  The Journal of Antibiotics Japan Antibiotics Research Association 48 (9) 1015 - 1020 0021-8820 1995 [Refereed]
  
• A New Melanin Biosynthesis Inhibitor, Melanoxadin from Fungal Metabolite by Using the Larval Haemolymph of the Silkworm, Bombyx mori.

  RYUJU HASHIMOTO; SENJI TAKAHASHI; KUNIKATSU HAMANO; AKIRA NAKAGAWA

  The Journal of Antibiotics Japan Antibiotics Research Association 48 (9) 1052 - 1054 0021-8820 1995 [Refereed]
  
• Biosynthesis of lactacystin. Origin of the carbons and stereospecific NMR assignment of the two diastereotopic methyl groups

  Akira Nakagawa; Senji Takahashi; Kenichi Uchida; Keiichi Matsuzaki; Satoshi Ōmura; Asao Nakamura; Noboru Kurihara; Tsuyoshi Nakamatsu; Yoko Miyake; Kanako Take; Masatsune Kainosho

  Tetrahedron Letters Elsevier BV 35 (28) 5009 - 5012 0040-4039 1994/07 [Refereed]
  
• New Method for Screening the Melanin Biosynthesis Inhibitor by Using the Larval Haemolymph of the Silkworm,Bombyx mori, and the Inhibitory Activity of Trichoviridin

  Ryuju Hashimoto; Senji Takahashi; Kunikatsu Hamano; Tadasu Mori; Akira Nakagawa

  Bioscience, Biotechnology, and Biochemistry Informa UK Limited 58 (9) 1725 - 1726 0916-8451 1994/01 [Refereed]
  
• Samarium (III) iodide promoted addition of diketene to aldehydes : A facile synthesis of δ-hydroxy-β-oxocarboxylates.

  Koji Abe; Senji Takahashi; Nobuo Mori

  Chemistry Express 6 (3) 193 - 196 1991/03 [Refereed]
  
• Radical coupling of β-bromostyrene with carbonyl compounds promoted by samarium (II) di-iodide.

  Koji Abe; Katsuhiko Uehara; Senji Takahashi; Nobuo Mori

  Chemistry Express 6 (3) 189 - 192 1991/03 [Refereed]
  
• Reductive cross-coupling of pyruvates with carbonyl compounds mediated by SmI2 : A facile synthesis of α,β-dihydroxycarboxylates.

  Koji Abe; Senji Takahashi; Nobuo Mori

  Chemistry Express 6 (1) 53 - 56 1991/01 [Refereed]
  
• Samarium(II) diiodide mediated coupling of bis(bromomethyl)arenes. Facile synthesis of [2n]cyclophanes without using high-dilution techniques

  Senji Takahashi; Nobuo Mori

  Journal of the Chemical Society, Perkin Transactions 1 (8) 2029 - 2032 1472-7781 1991 [Refereed]
  
• Novel transannular reactions in the acid hydrolysis of diazotized syn- and anti-4-amino[2.2] (1,4)naphthalenoparacyclophanes

  Yoshihiro Takada; Kazuhiko Tsuchiya; Senji Takahashi; Nobuo Mori

  Journal of the Chemical Society, Perkin Transactions 2 (12) 2141 - 2145 1472-779X 1990 [Refereed]
  
• A Simple Synthetic Method of [2.2]Cyclophanes by Lanthanoid-Mediated Coupling of Bis(bromomethyl)benzenes

  Senji Takahashi; Nobuo Mori

  Chemistry Letters 18 (1) 13 - 14 1989/01 [Refereed]
  

Research Grants & Projects

• Finding of new bioactive compounds from microorganisms, on the base of biosyunthetic studies on microbial secondary metabolites.

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 1992 -1993 

  Author : NAKAGAWA Akira; TAKAHASHI Senji