Hayashi ToshihiroPreclinical Medicine Professor and Chairman Department of Physiology Professor and Chairman | |||
A neurologist, brain-mapper, neurophysiologist, and neuroscientist eager to elucidate mechanism of neural plasticity and memory function and also to apply these insights to develop early diagnostic methods and cure for neurological illness, focusing on neurodegenerative diseases, namely Alzheimer’s disease and Parkinson's disease. Earlier work since the late 1990s addressed fMRI methodology and early resting-state functional connectivity in nonhuman primates.
Current research focuses on resting-state functional connectivity along the structural connectome, applied to large-scale lifespan cohorts (HCP, AABC, ADNI, PPMI) for early detection of cognitive aging. Method development integrates spectral graph signal processing and machine learning, with collaborative use of LLMs in the analysis workflow as a model case for AI for Science.