Tsukita Sachiko

Researcher Information

Affiliation

Advanced Comprehensive Research Organization (ACRO) Specially Appointed Professor
Graduate School of Medicine Specially Appointed Professor
Graduate School of Medicine Professor

URL

https://jglobal.jst.go.jp/detail?JGLOBAL_ID=201601012908924837

J-Global ID

• 201601012908924837

Research Areas

• Life sciences / Cell biology

Academic & Professional Experience

• 2022/04 - Today  Teikyo UniversityAdvanced Comprehensive Research OrganizationProfessor
• 2007/04 - 2022/03  Osaka University
• 2003/04 - 2007/03  Kyoto University
• 1994/04 - 2007/03  Kyoto UniversityFaculty of Medicine
• 1990/04 - 1993/03  Tokyo Medical and Dental UniversityFaculty of Medicine
• 1989/04 - 1990/03  Tokyo University of Pharmacy and Life Sciences

Education

• 1978/04 - 1983/03  The University of Tokyo
• 1976/04 - 1978/03  The University of Tokyo
• 1972/04 - 1976/03  The University of Tokyo  Faculty of Pharmaceutical Sciences

Association Memberships

• JAPAN SOCIETY FOR CELL BIOLOGY   THE MOLECULAR BIOLOGY SOCIETY OF JAPAN   THE JAPANESE BIOCHEMICAL SOCIETY   THE JAPANESE ASSOCIATION OF ANATOMISTS   THE JAPANESE CANCER ASSOCIATION   THE JAPANESE SOCIETY OF MICROSCOPY   アメリカ細胞生物学会   

Research Activity Information

Published Papers

• A short guide to the tight junction.

  Sandra Citi; Michael Fromm; Mikio Furuse; Lorenza González-Mariscal; Asma Nusrat; Sachiko Tsukita; Jerrold R Turner

  Journal of cell science 137 (9) 2024/05
• Dual-color live imaging unveils stepwise organization of multiple basal body arrays by cytoskeletons

  Gen Shiratsuchi; Satoshi Konishi; Tomoki Yano; Yuichi Yanagihashi; Shogo Nakayama; Tatsuya Katsuno; Hiroka Kashihara; Hiroo Tanaka; Kazuto Tsukita; Koya Suzuki; Elisa Herawati; Hitomi Watanabe; Toyohiro Hirai; Takeshi Yagi; Gen Kondoh; Shimpei Gotoh; Atsushi Tamura; Sachiko Tsukita

  EMBO Reports Springer Science and Business Media LLC 2024/02
• Double mutation of claudin-1 and claudin-3 causes alopecia in infant mice.

  Koya Suzuki; Kosuke Yamaga; Reitaro Tokumasu; Tatsuya Katsuno; Hiroo Tanaka; Shuhei Chiba; Takeshi Yagi; Ichiro Katayama; Atsushi Tamura; Hiroyuki Murota; Sachiko Tsukita

  Annals of the New York Academy of Sciences 1523 (1) 51 - 61 2023/03
• Phase separation of an actin nucleator by junctional microtubules regulates epithelial function.

  Kazuto Tsukita; Manabu Kitamata; Hiroka Kashihara; Tomoki Yano; Ikuko Fujiwara; Timothy F Day; Tatsuya Katsuno; Jaewon Kim; Fumiko Takenaga; Hiroo Tanaka; Sungsu Park; Makoto Miyata; Hitomi Watanabe; Gen Kondoh; Ryosuke Takahashi; Atsushi Tamura; Sachiko Tsukita

  Science advances 9 (7) eadf6358  2023/02
• Parallel cryo electron tomography on in situ lamellae.

  Fabian Eisenstein; Haruaki Yanagisawa; Hiroka Kashihara; Masahide Kikkawa; Sachiko Tsukita; Radostin Danev

  Nature methods 20 (1) 131 - 138 2022/12
• The tight junction protein occludin modulates blood-brain barrier integrity and neurological function after ischemic stroke in mice

  Shintaro Sugiyama; Tsutomu Sasaki; Hiroo Tanaka; Haomin Yan; Takeshi Ikegami; Hideaki Kanki; Kumiko Nishiyama; Goichi Beck; Yasufumi Gon; Shuhei Okazaki; Kenichi Todo; Atsushi Tamura; Sachiko Tsukita; Hideki Mochizuki

  Research Square Platform LLC 2022/11
• Deficiency of lung-specific claudin-18 leads to aggravated infection with Cryptococcus deneoformans through dysregulation of the microenvironment in lungs

  Ko Sato; Ikumi Matsumoto; Koya Suzuki; Atsushi Tamura; Aki Shiraishi; Hiroshi Kiyonari; Jun Kasamatsu; Hideki Yamamoto; Tomomitsu Miyasaka; Daiki Tanno; Anna Miyahara; Tong Zong; Takafumi Kagesawa; Akiho Oniyama; Kotone Kawamura; Yuki Kitai; Aya Umeki; Emi Kanno; Hiromasa Tanno; Keiko Ishii; Sachiko Tsukita; Kazuyoshi Kawakami

  Scientific Reports Springer Science and Business Media LLC 11 (1) 2021/12
• Daple deficiency causes hearing loss in adult mice by inducing defects in cochlear stereocilia and apical microtubules.

  Yoshiyuki Ozono; Atsushi Tamura; Shogo Nakayama; Elisa Herawati; Yukiko Hanada; Kazuya Ohata; Maki Takagishi; Masahide Takahashi; Takao Imai; Yumi Ohta; Kazuo Oshima; Takashi Sato; Hidenori Inohara; Sachiko Tsukita

  Scientific reports 11 (1) 20224 - 20224 2021/10
• Iqgap3-Ras axis drives stem cell proliferation in the stomach corpus during homoeostasis and repair

  Junichi Matsuo; Daisuke Douchi; Khine Myint; Naing Naing Mon; Akihiro Yamamura; Kazuyoshi Kohu; Dede Liana Heng; Sabirah Chen; Nur Astiana Mawan; Napat Nuttonmanit; Ying Li; Supriya Srivastava; Shamaine Wei Ting Ho; Nicole Yee Shin Lee; Hong Kai Lee; Makoto Adachi; Atsushi Tamura; Jinmiao Chen; Henry Yang; Ming Teh; Jimmy Bok-Yan So; Wei Peng Yong; Patrick Tan; Khay Guan Yeoh; Linda Shyue Huey Chuang; Sachiko Tsukita; Yoshiaki Ito

  Gut BMJ 70 (10) 1833 - 1846 0017-5749 2021/10
• 脳卒中後の血液脳関門タイトジャンクションにおけるoccludinの役割(The role of occludin in Tight Junction in Blood Brain Barrier after stroke)

  Sugiyama Shintaro; Sasaki Tsutomu; Tanaka Hiroo; Yan Haomin; Kanki Hideaki; Tamura Atsushi; Tsukita Sachiko; Mochizuki Hideki

  臨床神経学 (一社)日本神経学会 61 (Suppl.) S226 - S226 0009-918X 2021/09
• Multicellular modeling of ciliopathy by combining iPS cells and microfluidic airway-on-a-chip technology.

  Naoyuki Sone; Satoshi Konishi; Koichi Igura; Koji Tamai; Satoshi Ikeo; Yohei Korogi; Shuhei Kanagaki; Toshinori Namba; Yuki Yamamoto; Yifei Xu; Kazuhiko Takeuchi; Yuichi Adachi; Toyofumi F Chen-Yoshikawa; Hiroshi Date; Masatoshi Hagiwara; Sachiko Tsukita; Toyohiro Hirai; Yu-Suke Torisawa; Shimpei Gotoh

  Science translational medicine 13 (601) 2021/07
• Planar cell polarity induces local microtubule bundling for coordinated ciliary beating.

  Shogo Nakayama; Tomoki Yano; Toshinori Namba; Satoshi Konishi; Maki Takagishi; Elisa Herawati; Tomoki Nishida; Yasuo Imoto; Shuji Ishihara; Masahide Takahashi; Ken'ya Furuta; Kazuhiro Oiwa; Atsushi Tamura; Sachiko Tsukita

  The Journal of cell biology 220 (7) 2021/07
• A microtubule-LUZP1 association around tight junction promotes epithelial cell apical constriction.

  Tomoki Yano; Kazuto Tsukita; Hatsuho Kanoh; Shogo Nakayama; Hiroka Kashihara; Tomoaki Mizuno; Hiroo Tanaka; Takeshi Matsui; Yuhei Goto; Akira Komatsubara; Kazuhiro Aoki; Ryosuke Takahashi; Atsushi Tamura; Sachiko Tsukita

  The EMBO journal 40 (2) e104712  2021/01
• Uniaxial stretching device for studying maturity-dependent morphological response of epithelial cell monolayers to tensile strain.

  Kim, J; Tamura, A; Tsukita, S; Parl, S

  J Ind Eng Chem 99 282 - 291 2021 [Refereed]
  
• Inactivation of paracellular cation-selective claudin-2 channels attenuates immune-mediated experimental colitis in mice.

  Raju, P; Shashikanth, N; Tsai, PY; Pongkorpsakol, P; Chanez-Parades, S; Steinhagen, PR; Kuo, WT; Singh, G; Tsukita, S; Turner, JR

  J Clin Invest. 130 5197 - 5208 2020 [Refereed]
  
• Reciprocal Association between the Apical Junctional Complex and AMPK: A Promising Therapeutic Target for Epithelial/Endothelial Barrier Function?

  Kazuto Tsukita; Tomoki Yano; Atsushi Tamura; Sachiko Tsukita

  International journal of molecular sciences 20 (23) 2019/11 [Refereed]
  
• Odf2 haploinsufficiency causes a new type of decapitated and decaudated spermatozoa, Odf2-DDS, in mice.

  Chizuru Ito; Hidenori Akutsu; Ryoji Yao; Keiichi Yoshida; Kenji Yamatoya; Tohru Mutoh; Tsukasa Makino; Kazuhiro Aoyama; Hiroaki Ishikawa; Koshi Kunimoto; Sachiko Tsukita; Tetsuo Noda; Masahide Kikkawa; Kiyotaka Toshimori

  Scientific reports 9 (1) 14249 - 14249 2019/10 [Refereed]
  
• Vinculin is critical for the robustness of the epithelial cell sheet paracellular barrier for ions.

  Konishi S; Yano T; Tanaka H; Mizuno T; Kanoh H; Tsukita K; Namba T; Tamura A; Yonemura S; Gotoh S; Matsumoto H; Hirai T; Tsukita S

  Life science alliance 2 (4) 2019/08 [Refereed]
  
• Deficiency of Stomach-Type Claudin-18 in Mice Induces Gastric Tumor Formation Independent of H. Pylori Infection.

  Suzuki K; Sentani K; Tanaka H; Yano T; Suzuki K; Oshima M; Yasui W; Tamura A; Tsukita S

  Cellular and molecular gastroenterology and hepatology 2019/03 [Refereed]
  
• The Claudins: From Tight Junctions to Biological Systems.

  Tsukita S; Tanaka H; Tamura A

  Trends in biochemical sciences 44 (2) 141 - 152 0968-0004 2019/02 [Refereed]
  
• Morphologic determinant of tight junctions revealed by claudin-3 structures.

  Nakamura S; Irie K; Tanaka H; Nishikawa K; Suzuki H; Saitoh Y; Tamura A; Tsukita S; Fujiyoshi Y

  Nature communications 10 (1) 816  2019/02 [Refereed]
  
• R40.76 binds to the α domain of ZO-1: role of ZO-1 (α+) in epithelial differentiation and mechano-sensing.

  Rouaud, F; Vasileva, E; Spadaro, D; Tsukita, S; Citi, S

  Tissue Barriers 7 e1653748  2019
• Cep128 associates with Odf2 to form the subdistal appendage of the centriole.

  Kashihara H; Chiba S; Kanno SI; Suzuki K; Yano T; Tsukita S

  Genes to cells : devoted to molecular & cellular mechanisms 24 (3) 231 - 243 1356-9597 2019/01 [Refereed]
  
• Interleukin 22 Expands Transit-Amplifying Cells While Depleting Lgr5⁺ Stem Cells via Inhibition of Wnt and Notch Signaling.

  Zha JM; Li HS; Lin Q; Kuo WT; Jiang ZH; Tsai PY; Ding N; Wu J; Xu SF; Wang YT; Pan J; Zhou XM; Chen K; Tao M; Odenwald MA; Tamura A; Tsukita S; Turner JR; He WQ

  Cellular and molecular gastroenterology and hepatology 7 (2) 255 - 274 2019 [Refereed]
  
• Publisher Correction: AMPK-dependent phosphorylation of cingulin reversibly regulates its binding to actin filaments and microtubules.

  Yano T; Torisawa T; Oiwa K; Tsukita S

  Scientific reports 8 (1) 17991  2018/12 [Refereed]
  
• AMPK-dependent phosphorylation of cingulin reversibly regulates its binding to actin filaments and microtubules.

  Yano T; Torisawa T; Oiwa K; Tsukita S

  Scientific reports 8 (1) 15550  2018/10 [Refereed]
  
• 胃のおける細胞間接着装置タイトジャンクションの長期障害と胃腫瘍の発生

  鈴木 浩也; 仙谷 和弘; 田中 啓雄; 矢野 智樹; 鈴木 和男; 田村 淳; 月田 早智子

  日本生化学会大会プログラム・講演要旨集 (公社)日本生化学会 91回 [3P - 279] 2018/09
• Claudin-3 regulates bile canalicular paracellular barrier and cholesterol gallstone cores formation in mice.

  Tanaka H; Imasato M; Yamazaki Y; Matsumoto K; Kunimoto K; Delpierre J; Meyer K; Zerial M; Kitamura N; Watanabe M; Tamura A; Tsukita S

  Journal of hepatology 69 (6) 1308 - 1316 0168-8278 2018/09 [Refereed]
  
• Claudin-3 Loss Causes Leakage of Sweat from the Sweat Gland to Contribute to the Pathogenesis of Atopic Dermatitis

  Kosuke Yamaga; Hiroyuki Murota; Atsushi Tamura; Hirofumi Miyata; Masato Ohmi; Junichi Kikuta; Masaru Ishii; Sachiko Tsukita; Ichiro Katayama

  Journal of Investigative Dermatology Elsevier B.V. 138 (6) 1279 - 1287 1523-1747 2018/06 [Refereed]
  
• エクリン汗腺の構造と動態観察による発汗制御メカニズムの解明

  室田 浩之; 谷 佐起; 山賀 康右; 小野 慧美; 田村 淳; 菊田 順一; 近江 雅人; 月田 早智子; 石井 優; 関口 清俊; 片山 一朗

  日本皮膚科学会雑誌 (公社)日本皮膚科学会 128 (5) 1173 - 1173 0021-499X 2018/05 [Refereed]
  
• Selective insulin resistance with differential expressions of IRS-1 and IRS-2 in human NAFLD livers

  Honma M; Sawada S; Ueno Y; Murakami K; Yamada T; Gao J; Kodama S; Izumi T; Takahashi K; Tsukita S; Uno K; Imai J; Kakazu E; Kondo Y; Mizuno K; Kawagishi N; Shimosegawa T; Katagiri H

  Int J Obes (Lond) 42 (9) 1544 - 1555 2018 [Refereed]
  
• Apical cytoskeletons and junctional complexes as a combined system in epithelial cell sheets

  Tomoki Yano; Hatsuho Kanoh; Atsushi Tamura; Sachiko Tsukita

  ANNALS OF THE NEW YORK ACADEMY OF SCIENCES WILEY 1405 (1) 32 - 43 0077-8923 2017/10 [Refereed]
  
• Site-specific distribution of claudin-based paracellular channels with roles in biological fluid flow and metabolism

  Hiroo Tanaka; Atsushi Tamura; Koya Suzuki; Sachiko Tsukita

  ANNALS OF THE NEW YORK ACADEMY OF SCIENCES WILEY 1405 (1) 44 - 52 0077-8923 2017/10 [Refereed]
  
• Time- and dose-dependent claudin contribution to biological functions: Lessons from claudin-1 in skin

  Reitaro Tokumasu; Atsushi Tamura; Sachiko Tsukita

  Tissue Barriers Taylor and Francis Inc. 5 (3) e1336194  2168-8370 2017/07 [Refereed]
  
• IL-22 Upregulates Epithelial Claudin-2 to Drive Diarrhea and Enteric Pathogen Clearance

  Pei-Yun Tsai; Bingkun Zhang; Wei-Qi He; Juan-Min Zha; Matthew A. Odenwald; Gurminder Singh; Atsushi Tamura; Le Shen; Anne Sailer; Sunil Yeruva; Wei-Ting Kuo; Yang-Xin Fu; Sachiko Tsukita; Jerrold R. Turner

  CELL HOST & MICROBE CELL PRESS 21 (6) 671 - + 1931-3128 2017/06 [Refereed]
  
• 血管炎・その他の免疫疾患 皮膚限局の血管炎が重症化した際の抗モエシン抗体の推移について

  岡野 達郎; 竹内 そら; 相馬 良直; 鈴木 浩也; 月田 早智子; 石津 明洋; 鈴木 和男; 川上 民裕

  アレルギー (一社)日本アレルギー学会 66 (4-5) 621 - 621 0021-4884 2017/05
• 分子の集合・離脱がつかさどる動的な細胞機能 中心体機能制御インターフェースとしてのアペンデージ構造の分子基盤

  柏原 宏香; 千葉 秀平; 菅野 新一郎; 月田 早智子

  日本細胞生物学会大会講演要旨集 (一社)日本細胞生物学会 69回 11 - 11 2017/05
• Activation of the Hypoxia Inducible Factor 1 alpha Subunit Pathway in Steatotic Liver Contributes to Formation of Cholesterol Gallstones

  Yoichiro Asai; Tetsuya Yamada; Sohei Tsukita; Kei Takahashi; Masamitsu Maekawa; Midori Honma; Masanori Ikeda; Keigo Murakami; Yuichiro Munakata; Yuta Shirai; Shinjiro Kodama; Takashi Sugisawa; Yumiko Chiba; Yasuteru Kondo; Keizo Kaneko; Kenji Uno; Shojiro Sawada; Junta Imai; Yasuhiro Nakamura; Hiroaki Yamaguchi; Kozo Tanaka; Hironobu Sasano; Nariyasu Mano; Yoshiyuki Ueno; Tooru Shimosegawa; Hideki Katagiri

  GASTROENTEROLOGY W B SAUNDERS CO-ELSEVIER INC 152 (6) 1521 - + 0016-5085 2017/05 [Refereed]
  
• Interaction between Plasmodium Glycosylphosphatidylinositol and the Host Protein Moesin Has No Implication in Malaria Pathology

  Josefine Dunst; Nahid Azzouz; Xinyu Liu; Sachiko Tsukita; Peter H. Seeberger; Faustin Kamena

  FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY FRONTIERS MEDIA SA 7 183  2235-2988 2017/05 [Refereed]
  
• Claudin-1の発現低下による皮膚恒常性の破綻

  山賀 康右; 室田 浩之; 片山 一朗; 徳増 玲太郎; 山崎 裕自; 鈴木 浩也; 田村 淳; 月田 早智子

  角化症研究会記録集 31 59 - 64 2017/03
• Regulation of intestinal homeostasis by the ulcerative colitis-associated gene RNF186.

  Kosuke Fujimoto; Makoto Kinoshita; Hiroo Tanaka; Daisuke Okuzaki; Yosuke Shimada; Hisako Kayama; Ryu Okumura; Yoki Furuta; Masashi Narazaki; Atsushi Tamura; Shigetsugu Hatakeyama; Masahito Ikawa; Kiichiro Tsuchiya; Mamoru Watanabe; Atsushi Kumanogoh; Sachiko Tsukita; Kiyoshi Takeda

  Mucosal Immunol 10 (2) 446 - 459 1935-3456 2017/03 [Refereed]
  
• Regulation of intestinal homeostasis by the ulcerative colitis-associated gene RNF186

  Kosuke Fujimoto; Makoto Kinoshita; Hiroo Tanaka; Daisuke Okuzaki; Yosuke Shimada; Hisako Kayama; Ryu Okumura; Yoki Furuta; Masashi Narazaki; Atsushi Tamura; Shigetsugu Hatakeyama; Masahito Ikawa; Kiichiro Tsuchiya; Mamoru Watanabe; Atsushi Kumanogoh; Sachiko Tsukita; Kiyoshi Takeda

  MUCOSAL IMMUNOLOGY NATURE PUBLISHING GROUP 10 (2) 446 - 459 1933-0219 2017/03 [Refereed]
  
• Three-dimensional Organization of Layered Apical Cytoskeletal Networks Associated with Mouse Airway Tissue Development

  Kazuhiro Tateishi; Tomoki Nishida; Kanako Inoue; Sachiko Tsukita

  SCIENTIFIC REPORTS NATURE PUBLISHING GROUP 7 43783  2045-2322 2017/03 [Refereed]
  
• MicroRNAs 106b and 222 Improve Hyperglycemia in a Mouse Model of Insulin-Deficient Diabetes via Pancreatic beta-Cell Proliferation

  Sohei Tsukita; Tetsuya Yamada; Kei Takahashi; Yuichiro Munakata; Shinichiro Hosaka; Hironobu Takahashi; Junhong Gao; Yuta Shirai; Shinjiro Kodama; Yoichiro Asai; Takashi Sugisawa; Yumiko Chiba; Keizo Kaneko; Kenji Uno; Shojiro Sawada; Junta Imai; Hideki Katagiri

  EBIOMEDICINE ELSEVIER SCIENCE BV 15 163 - 172 2352-3964 2017/02 [Refereed]
  
• Presence of anti-phosphatidylserine-prothrombin complex antibodies and anti-moesin antibodies in patients with polyarteritis nodosa

  Tatsuro Okano; Sora Takeuchi; Yoshinao Soma; Koya Suzuki; Sachiko Tsukita; Akihiro Ishizu; Kazuo Suzuki; Tamihiro Kawakami

  JOURNAL OF DERMATOLOGY WILEY 44 (1) 18 - 22 0385-2407 2017/01 [Refereed]
  
• Multiciliated cell basal bodies align in stereotypical patterns coordinated by the apical cytoskeleton

  Elisa Herawati; Daisuke Taniguchi; Hatsuho Kanoh; Kazuhiro Tateishi; Shuji Ishihara; Sachiko Tsukita

  JOURNAL OF CELL BIOLOGY ROCKEFELLER UNIV PRESS 214 (5) 571 - 586 0021-9525 2016/08 [Refereed]
  
• 汗腺の構造/機能解析の最前線 Claudin-3が汗腺からの汗の漏出を止める

  山賀 康右; 室田 浩之; 宮田 浩史; 近江 雅人; 菊田 順一; 石井 優; 田村 淳; 月田 早智子; 片山 一朗

  日本発汗学会総会プログラム・抄録集 日本発汗学会 24回 31 - 31 2016/07 [Refereed]
  
• Dose-dependent role of claudin-1 in vivo in orchestrating features of atopic dermatitis

  Reitaro Tokumasu; Kosuke Yamaga; Yuji Yamazaki; Hiroyuki Murota; Koya Suzuki; Atsushi Tamura; Kana Bando; Yasuhide Furuta; Ichiro Katayama; Sachiko Tsukita

  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA NATL ACAD SCIENCES 113 (28) E4061 - E4068 0027-8424 2016/07 [Refereed]
  
• Water-based biological homeostasis in multiple fluid-filled compartments in the higher organisms: Regulation by the paracellular barrier-forming tight junctions of epithelial cell sheets

  Yuji Yamazaki; Atsushi Tamura; Sachiko Tsukita

  Water: The Forgotten Biological Molecule Pan Stanford Publishing Pte. Ltd. 247 - 258 2016/04
• ヒトiPS細胞から機能的な気道線毛上皮細胞への分化誘導

  Satoshi Konishi; Shimpei Goto; Kazuhiro Tateishi; Yuki Yamamoto; Yohei Korogi; Tadao Nagasaki; Hisako Matsumoto; Shigeo Muro; Toyohiro Hirai; Isao Ito; Sachiko Tsukita; Michiaki Mishima

  日本呼吸器学会誌 5 (増刊号) 143  2016/03
• Claudin-21 Has a Paracellular Channel Role at Tight Junctions

  Hiroo Tanaka; Yasuko Yamamoto; Hiroka Kashihara; Yuji Yamazaki; Kazutoshi Tani; Yoshinori Fujiyoshi; Katsuhiko Mineta; Kosei Takeuchi; Atsushi Tamura; Sachiko Tsukita

  MOLECULAR AND CELLULAR BIOLOGY AMER SOC MICROBIOLOGY 36 (6) 954 - 964 0270-7306 2016/03 [Refereed]
  
• Fer tyrosine kinase oligomer mediates and amplifies Src-induced tumor progression

  C. Oneyama; Y. Yoshikawa; Y. Ninomiya; T. Iino; S. Tsukita; M. Okada

  ONCOGENE NATURE PUBLISHING GROUP 35 (4) 501 - 512 0950-9232 2016/01 [Refereed]
  
• Directed Induction of Functional Multi-ciliated Cells in Proximal Airway Epithelial Spheroids from Human Pluripotent Stem Cells

  Satoshi Konishi; Shimpei Gotoh; Kazuhiro Tateishi; Yuki Yamamoto; Yohei Korogi; Tadao Nagasaki; Hisako Matsumoto; Shigeo Muro; Toyohiro Hirai; Isao Ito; Sachiko Tsukita; Michiaki Mishima

  STEM CELL REPORTS CELL PRESS 6 (1) 18 - 25 2213-6711 2016/01 [Refereed]
  
• Deletion of Tricellulin Causes Progressive Hearing Loss Associated with Degeneration of Cochlear Hair Cells

  Toru Kamitani; Hirofumi Sakaguchi; Atsushi Tamura; Takenori Miyashita; Yuji Yamazaki; Reitaro Tokumasu; Ryuhei Inamoto; Ai Matsubara; Nozomu Mori; Yasuo Hisa; Sachiko Tsukita

  SCIENTIFIC REPORTS NATURE PUBLISHING GROUP 5 18402  2045-2322 2015/12 [Refereed]
  
• Intestinal deletion of Claudin-7 enhances paracellular organic solute flux and initiates colonic inflammation in mice

  Hiroo Tanaka; Maki Takechi; Hiroshi Kiyonari; Go Shioi; Atsushi Tamura; Sachiko Tsukita

  GUT BMJ PUBLISHING GROUP 64 (10) 1529 - U209 0017-5749 2015/10 [Refereed]
  
• Knockdown of Ezrin Causes Intrahepatic Cholestasis by the Dysregulation of Bile Fluidity in the Bile Duct Epithelium in Mice

  Ryo Hatano; Kaori Akiyama; Atsushi Tamura; Shigekuni Hosogi; Yoshinori Marunaka; Michael J. Caplan; Yoshiyuki Ueno; Sachiko Tsukita; Shinji Asano

  HEPATOLOGY WILEY-BLACKWELL 61 (5) 1660 - 1671 0270-9139 2015/05 [Refereed]
  
• Radixin regulates synaptic GABA(A) receptor density and is essential for reversal learning and short-term memory

  Torben J. Hausrat; Mary Muhia; Kimberly Gerrow; Philip Thomas; Wiebke Hirdes; Sachiko Tsukita; Frank F. Heisler; Lena Herich; Sylvain Dubroqua; Petra Breiden; Joram Feldon; Juergen R. Schwarz; Benjamin K. Yee; Trevor G. Smart; Antoine Triller; Matthias Kneussel

  NATURE COMMUNICATIONS NATURE PUBLISHING GROUP 6 6872  2041-1723 2015/04 [Refereed]
  
• Moesin and myosin phosphatase confine neutrophil orientation in a chemotactic gradient

  Xiaowen Liu; Tao Yang; Koya Suzuki; Sachiko Tsukita; Masaru Ishii; Shuping Zhou; Gang Wang; Luyang Cao; Feng Qian; Shalina Taylor; Myung-Jin Oh; Irena Levitan; Richard D. Ye; Graeme K. Carnegie; Yong Zhao; Asrar B. Malik; Jingsong Xu

  JOURNAL OF EXPERIMENTAL MEDICINE ROCKEFELLER UNIV PRESS 212 (2) 267 - 280 0022-1007 2015/02 [Refereed]
  
• Structural insight into tight junction disassembly by Clostridium perfringens enterotoxin

  Yasunori Saitoh; Hiroshi Suzuki; Kazutoshi Tani; Kouki Nishikawa; Katsumasa Irie; Yuki Ogura; Atsushi Tamura; Sachiko Tsukita; Yoshinori Fujiyoshi

  SCIENCE AMER ASSOC ADVANCEMENT SCIENCE 347 (6223) 775 - 778 0036-8075 2015/02 [Refereed]
  
• Model for the Architecture of Claudin-Based Paracellular Ion Channels through Tight Junctions

  Hiroshi Suzuki; Kazutoshi Tani; Atsushi Tamura; Sachiko Tsukita; Yoshinori Fujiyoshi

  JOURNAL OF MOLECULAR BIOLOGY ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD 427 (2) 291 - 297 0022-2836 2015/01 [Refereed]
  
• Paracellular barrier and channel functions of TJ claudins in organizing biological systems: Advances in the field of barriology revealed in knockout mice

  Atsushi Tamura; Sachiko Tsukita

  SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD 36 177 - 185 1084-9521 2014/12 [Refereed]
  
• Claudin 2 deficiency reduces bile flow and increases susceptibility to cholesterol gallstone disease in mice.

  Kengo Matsumoto; Mitsunobu Imasato; Yuji Yamazaki; Hiroo Tanaka; Mitsuhiro Watanabe; Hidetoshi Eguchi; Hiroaki Nagano; Hayato Hikita; Tomohide Tatsumi; Tetsuo Takehara; Atsushi Tamura; Sachiko Tsukita

  Gastroenterology 147 (5) 1134 - 45 0016-5085 2014/11 [Refereed]
  
• Involvement of IQGAP family proteins in the regulation of mammalian cell cytokinesis

  Makoto Adachi; Asami Kawasaki; Hisashi Nojima; Eisuke Nishida; Sachiko Tsukita

  GENES TO CELLS WILEY-BLACKWELL 19 (11) 803 - 820 1356-9597 2014/11 [Refereed]
  
• Ezrin Mediates Neuritogenesis via Down-Regulation of RhoA Activity in Cultured Cortical Neurons

  Yosuke Matsumoto; Masatoshi Inden; Atsushi Tamura; Ryo Hatano; Sachiko Tsukita; Shinji Asano

  PLOS ONE PUBLIC LIBRARY SCIENCE 9 (8) e105435  1932-6203 2014/08 [Refereed]
  
• Fetal Growth Retardation and Lack of Hypotaurine in Ezrin Knockout Mice

  Tomohiro Nishimura; Kei Higuchi; Yoshimichi Sai; Yuki Sugita; Yuko Yoshida; Masatoshi Tomi; Masami Wada; Tomohiko Wakayama; Atsushi Tamura; Sachiko Tsukita; Tomoyoshi Soga; Emi Nakashima

  PLOS ONE PUBLIC LIBRARY SCIENCE 9 (8) e105423  1932-6203 2014/08 [Refereed]
  
• A novel autoantibody against moesin in the serum of patients with MPO-ANCA-associated vasculitis

  Koya Suzuki; Tomokazu Nagao; Mitsuyo Itabashi; Yoshitomo Hamano; Ryuichi Sugamata; Yuji Yamazaki; Wako Yumura; Sachiko Tsukita; Pi-Chao Wang; Toshinori Nakayama; Kazuo Suzuki

  NEPHROLOGY DIALYSIS TRANSPLANTATION OXFORD UNIV PRESS 29 (6) 1168 - 1177 0931-0509 2014/06 [Refereed]
  
• Crystal Structure of a Claudin Provides Insight into the Architecture of Tight Junctions

  Hiroshi Suzuki; Tomohiro Nishizawa; Kazutoshi Tani; Yuji Yamazaki; Atsushi Tamura; Ryuichiro Ishitani; Naoshi Dohmae; Sachiko Tsukita; Osamu Nureki; Yoshinori Fujiyoshi

  SCIENCE AMER ASSOC ADVANCEMENT SCIENCE 344 (6181) 304 - 307 0036-8075 2014/04 [Refereed]
  
• Two appendages homologous between basal bodies and centrioles are formed using distinct Odf2 domains

  Kazuhiro Tateishi; Yuji Yamazaki; Tomoki Nishida; Shin Watanabe; Koshi Kunimoto; Hiroaki Ishikawa; Sachiko Tsukita

  JOURNAL OF CELL BIOLOGY ROCKEFELLER UNIV PRESS 203 (3) 417 - 425 0021-9525 2013/11 [Refereed]
  
• The association of microtubules with tight junctions is promoted by cingulin phosphorylation by AMPK

  Tomoki Yano; Takeshi Matsui; Atsushi Tamura; Masami Uji; Sachiko Tsukita

  JOURNAL OF CELL BIOLOGY ROCKEFELLER UNIV PRESS 203 (4) 605 - 614 0021-9525 2013/11 [Refereed]
  
• Tight Junctions

  S. Tsukita

  Encyclopedia of Biological Chemistry: Second Edition Elsevier Inc. 187 - 189 2013/02 [Refereed]
  
• Ezrin Is Required for the Functional Regulation of the Epithelial Sodium Proton Exchanger, NHE3

  Hisayoshi Hayashi; Atsushi Tamura; Devishree Krishnan; Sachiko Tsukita; Yuichi Suzuki; Hetal S. Kocinsky; Peter S. Aronson; John Orlowski; Sergio Grinstein; R. Todd Alexander

  PLoS ONE 8 (2) e55623  1932-6203 2013/02 [Refereed]
  
• Loss of Claudins 2 and 15 From Mice Causes Defects in Paracellular Na+ Flow and Nutrient Transport in Gut and Leads to Death from Malnutrition

  Masami Wada; Atsushi Tamura; Nobuyuki Takahashi; Sachiko Tsukita

  GASTROENTEROLOGY W B SAUNDERS CO-ELSEVIER INC 144 (2) 369 - 380 0016-5085 2013/02 [Refereed]
  
• Strand formation by a trimeric unit repeat of four-transmembrane proteins in Euglena

  H. Suzuki; Y. Ito; Y. Yamazaki; K. Mineta; M. Uji; K. Abe; K. Tani; Y. Fujiyoshi; S. Tsukita

  Nat. Commun 4 2041-1723 2013 [Refereed]
  
• The four-transmembrane protein IP39 of Euglena forms strands by a trimeric unit repeat.

  Hiroshi Suzuki; Yasuyuki Ito; Yuji Yamazaki; Katsuhiko Mineta; Masami Uji; Kazuhiro Abe; Kazutoshi Tani; Yoshinori Fujiyoshi; Sachiko Tsukita

  Nature communications 4 1766 - 1766 2013 [Refereed]
  
• EpCAM contributes to formation of functional tight junction in the intestinal epithelium by recruiting claudin proteins

  Zili Lei; Takako Maeda; Atsushi Tamura; Tetsuya Nakamura; Yuji Yamazaki; Hidetaka Shiratori; Kenta Yashiro; Sachiko Tsukita; Hiroshi Hamada

  DEVELOPMENTAL BIOLOGY ACADEMIC PRESS INC ELSEVIER SCIENCE 371 (2) 136 - 145 0012-1606 2012/11 [Refereed]
  
• Moesin-deficient mice reveal a non-redundant role for moesin in lymphocyte homeostasis

  Takako Hirata; Akira Nomachi; Kazuo Tohya; Masayuki Miyasaka; Sachiko Tsukita; Takeshi Watanabe; Shuh Narumiya

  INTERNATIONAL IMMUNOLOGY OXFORD UNIV PRESS 24 (11) 705 - 717 0953-8178 2012/11 [Refereed]
  
• Rho GTP exchange factor ARHGEF11 regulates the integrity of epithelial junctions by connecting ZO-1 and RhoA-Myosin II signaling

  Masahiko Itoh; Sachiko Tsukita; Yuji Yamazaki; Hiroyuki Sugimoto

  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA NATL ACAD SCIENCES 109 (25) 9905 - 9910 0027-8424 2012/06 [Refereed]
  
• A novel smooth septate junction-associated membrane protein, Snakeskin, is required for intestinal barrier function in Drosophila.

  Yanagihashi Y; Usui T; Izumi Y; Yonemura S; Sumida M; Tsukita S; Uemura T; Furuse M

  Journal of cell science 0021-9533 2012/02 [Refereed]
  
• Deficiency of Claudin-18 Causes Paracellular H+ Leakage, Up-regulation of Interleukin-1 beta, and Atrophic Gastritis in Mice

  Daisuke Hayashi; Atsushi Tamura; Hiroo Tanaka; Yuji Yamazaki; Shin Watanabe; Koya Suzuki; Kazuo Suzuki; Kazuhiro Sentani; Wataru Yasui; Hiromi Rakugi; Yoshitaka Isaka; Sachiko Tsukita

  GASTROENTEROLOGY W B SAUNDERS CO-ELSEVIER INC 142 (2) 292 - 304 0016-5085 2012/02 [Refereed]
  
• Coordinated Ciliary Beating Requires Odf2-Mediated Polarization of Basal Bodies via Basal Feet

  Koshi Kunimoto; Yuji Yamazaki; Tomoki Nishida; Kyosuke Shinohara; Hiroaki Ishikawa; Toshiaki Hasegawa; Takeshi Okanoue; Hiroshi Hamada; Tetsuo Noda; Atsushi Tamura; Shoichiro Tsukita; Sachiko Tsukita

  CELL CELL PRESS 148 (1-2) 189 - 200 0092-8674 2012/01 [Refereed]
  
• Claudin-based paracellular proton barrier in the stomach

  Atsushi Tamura; Yuji Yamazaki; Daisuke Hayashi; Koya Suzuki; Kazuhiro Sentani; Wataru Yasui; Sachiko Tsukita

  BARRIERS AND CHANNELS FORMED BY TIGHT JUNCTION PROTEINS II BLACKWELL SCIENCE PUBL 1258 108 - 114 0077-8923 2012 [Refereed]
  
• Claudin-18の欠損はマウスのparacellar proton leak、IL-1の上昇、萎縮性胃炎を引き起こす(Deficiency of Claudin-18 cause paracellular proton leak,up-regulation IL-1and atrophic gastritis in mice)

  林 大祐; 田村 淳; 田中 啓雄; 山崎 裕自; 渡辺 慎; 鈴木 浩也; 鈴木 和男; 仙谷 和弘; 安井 弥; 猪阪 善隆; 楽木 宏実; 月田 早智子

  日本生化学会大会プログラム・講演要旨集 (公社)日本生化学会 84回 3P - 0565 2011/09
• MPO-ANCA関連血管炎における新規自己抗体(抗モエシン抗体)の関与と機能解析

  鈴木 浩也; 長尾 朋和; 板橋 美津代; 山崎 裕自; 湯村 和子; 鈴木 和男; 月田 早智子

  日本生化学会大会プログラム・講演要旨集 (公社)日本生化学会 84回 4P - 0518 2011/09
• Role of claudin species-specific dynamics in reconstitution and remodeling of the zonula occludens

  Yuji Yamazaki; Reitaro Tokumasu; Hiroshi Kimura; Sachiko Tsukita

  MOLECULAR BIOLOGY OF THE CELL AMER SOC CELL BIOLOGY 22 (9) 1495 - 1504 1059-1524 2011/05 [Refereed]
  
• Tara up-regulates E-cadherin transcription by binding to the Trio RhoGEF and inhibiting Rac signaling

  Tomoki Yano; Yuji Yamazaki; Makoto Adachi; Katsuya Okawa; Philippe Fort; Masami Uji; Shoichiro Tsukita; Sachiko Tsukita

  JOURNAL OF CELL BIOLOGY ROCKEFELLER UNIV PRESS 193 (2) 319 - 332 0021-9525 2011/04 [Refereed]
  
• Trichoplein controls microtubule anchoring at the centrosome by binding to Odf2 and ninein.

  Miho Ibi; Peng Zou; Akihito Inoko; Takashi Shiromizu; Makoto Matsuyama; Yuko Hayashi; Masato Enomoto; Daisuke Mori; Shinji Hirotsune; Tohru Kiyono; Sachiko Tsukita; Hidemasa Goto; Masaki Inagaki

  Journal of cell science 124 (Pt 6) 857 - 64 0021-9533 2011/03 [Refereed]
  
• Loss of Claudin-15, but Not Claudin-2, Causes Na+ Deficiency and Glucose Malabsorption in Mouse Small Intestine

  Atsushi Tamura; Hisayoshi Hayashi; Mitsunobu Imasato; Yuji Yamazaki; Asuka Hagiwara; Masami Wada; Tetsuo Noda; Mitsuhiro Watanabe; Yuichi Suzuki; Sachiko Tsukita

  GASTROENTEROLOGY W B SAUNDERS CO-ELSEVIER INC 140 (3) 913 - 923 0016-5085 2011/03 [Refereed]
  
• Novel expression of claudin-5 in glomerular podocytes

  Ryo Koda; Linning Zhao; Eishin Yaoita; Yutaka Yoshida; Sachiko Tsukita; Atsushi Tamura; Masaaki Nameta; Ying Zhang; Hidehiko Fujinaka; Sameh Magdeldin; Bo Xu; Ichiei Narita; Tadashi Yamamoto

  CELL AND TISSUE RESEARCH SPRINGER 343 (3) 637 - 648 0302-766X 2011/03 [Refereed]
  
• Predicted expansion of the claudin multigene family

  Katsuhiko Mineta; Yasuko Yamamoto; Yuji Yamazaki; Hiroo Tanaka; Yukiyo Tada; Kuniaki Saito; Atsushi Tamura; Michihiro Igarashi; Toshinori Endo; Kosei Takeuchi; Sachiko Tsukita

  FEBS LETTERS ELSEVIER SCIENCE BV 585 (4) 606 - 612 0014-5793 2011/02 [Refereed]
  
• Immunohistochemical analysis in the cerebral cortex of ezrin knockdown mice

  Masatoshi Inden; Yosuke Matsumoto; Naoki Hattori; Kenichi Mukaisho; Takanori Hattori; Atsushi Tamura; Sachiko Tsukita; Shinji Asano

  JOURNAL OF PHARMACOLOGICAL SCIENCES JAPANESE PHARMACOLOGICAL SOC 115 240P - 240P 1347-8613 2011 [Refereed]
  
• Water-based biological homeostasis in multiple fluid-filled compartments in the higher organisms: Regulation by the paracellular barrier-forming tight junctions of epithelial cell sheets

  Yuji Yamazaki; Atsushi Tamura; Sachiko Tsukita

  Water: The Forgotten Biological Molecule Pan Stanford Publishing Pte. Ltd. 247 - 258 2010/11 [Refereed]
  
• Differential Expression of Ezrin and CLP36 in the Two Layers of Syncytiotrophoblast in Rats

  Kei Higuchi; Hisashi Iizasa; Yoshimichi Sai; Satomi Horieya; Kyeong-Eun Lee; Masami Wada; Masayuki Deguchi; Tomohiro Nishimura; Tomohiko Wakayama; Atsushi Tamura; Sachiko Tsukita; Noriko Kose; Young-Sook Kang; Emi Nakashima

  BIOLOGICAL & PHARMACEUTICAL BULLETIN PHARMACEUTICAL SOC JAPAN 33 (8) 1400 - 1406 0918-6158 2010/08 [Refereed]
  
• The Molecular Basis of Vascular Lumen Formation in the Developing Mouse Aorta

  Boris Strilic; Tomas Kucera; Jan Eglinger; Michael R. Hughes; Kelly M. McNagny; Sachiko Tsukita; Elisabetta Dejana; Napoleone Ferrara; Eckhard Lammert

  DEVELOPMENTAL CELL CELL PRESS 17 (4) 505 - 515 1534-5807 2009/10 [Refereed]
  
• Involvement of IQGAP3, a Regulator of Ras/ERK-Related Cascade, in Hepatocyte Proliferation in Mouse Liver Regeneration and Development

  Koshi Kunimoto; Hisashi Nojima; Yuji Yamazaki; Toshikazu Yoshikawa; Takeshi Okanoue; Sachiko Tsukita

  JOURNAL OF CELLULAR PHYSIOLOGY WILEY-LISS 220 (3) 621 - 631 0021-9541 2009/09 [Refereed]
  
• ケラチン結合蛋白質trichopleinは微小管のanchoringを制御し、Primary cilia形成を抑制する(Trichoplein, a keratin-binding protein, maker of microtubule-organization and breaker of cilia assembly)

  衣斐 美歩; 鄒 鵬; 猪子 誠人; 大室 有紀[松山]; 松山 誠; 白水 崇; 林 裕子; 森 大輔; 広常 真治; 米村 重信; 月田 早智子; 稲垣 昌樹

  日本細胞生物学会大会講演要旨集 (一社)日本細胞生物学会 61回 177 - 177 2009/05
• Similar and Distinct Properties of MUPP1 and Patj, Two Homologous PDZ Domain-Containing Tight-Junction Proteins

  Makoto Adachi; Yoko Hamazaki; Yuka Kobayashi; Masahiko Itoh; Sachiko Tsukita; Mikio Furuse; Shoichiro Tsukita

  MOLECULAR AND CELLULAR BIOLOGY AMER SOC MICROBIOLOGY 29 (9) 2372 - 2389 0270-7306 2009/05 [Refereed]
  
• Posttranslational regulation of Abcc2 expression by SUMOylation system

  Satoko Minami; Kousei Ito; Masashi Honma; Yuki Ikebuchi; Naohiko Anzai; Yoshikatsu Kanai; Tamotsu Nishida; Sachiko Tsukita; Shuichi Sekine; Toshiharu Horie; Hiroshi Suzuki

  AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY AMER PHYSIOLOGICAL SOC 296 (2) G406 - G413 0193-1857 2009/02 [Refereed]
  
• Roles of ZO-1 and ZO-2 in Establishment of the Belt-like Adherens and Tight Junctions with Paracellular Permselective Barrier Function

  Sachiko Tsukita; Tatsuya Katsuno; Yuji Yamazaki; Kazuaki Umeda; Atsushi Tamura; Shoichiro Tsukita

  MOLECULAR STRUCTURE AND FUNCTION OF THE TIGHT JUNCTION: FROM BASIC MECHANISMS TO CLINICAL MANIFESTATIONS WILEY-BLACKWELL 1165 44 - 52 0077-8923 2009 [Refereed]
  
• Sentan: A Novel Specific Component of the Apical Structure of Vertebrate Motile Cilia

  Akiharu Kubo; Akiko Yuba-Kubo; Sachiko Tsukita; Shoichiro Tsukita; Masayuki Amagai

  MOLECULAR BIOLOGY OF THE CELL AMER SOC CELL BIOLOGY 19 (12) 5338 - 5346 1059-1524 2008/12 [Refereed]
  
• ケラチン結合蛋白質Trichopleinの中心体における機能解析(Trichoplein, a keratin binding protein, is a functional component of centrosomes)

  大室 有紀[松山]; 鄒 鵬; 猪子 誠人; 衣斐 美歩; 米村 重信; 林 裕子; 森 大輔; 広常 真治; 田村 淳; 月田 早智子; 稲垣 昌樹

  日本生化学会大会・日本分子生物学会年会合同大会講演要旨集 (公社)日本生化学会 81回・31回 4T12 - 6 2008/11
• Tight junction-based epithelial microenvironment and cell proliferation

  S. Tsukita; Y. Yamazaki; T. Katsuno; A. Tamura; S. Tsukita

  ONCOGENE NATURE PUBLISHING GROUP 27 (55) 6930 - 6938 0950-9232 2008/11 [Refereed]
  
• Loss of Occludin Affects Tricellular Localization of Tricellulin

  Junichi Ikenouchi; Hiroyuki Sasaki; Sachiko Tsukita; Mikio Furuse; Shoichiro Tsukita

  MOLECULAR BIOLOGY OF THE CELL AMER SOC CELL BIOLOGY 19 (11) 4687 - 4693 1059-1524 2008/11 [Refereed]
  
• Dysregulation of lung injury and repair in moesin-deficient mice treated with intratracheal bleomycin

  Soshi Hashimoto; Fumimasa Amaya; Hiroki Matsuyama; Hiroshi Ueno; Shojiro Kikuchi; Masaki Tanaka; Yoshihisa Watanabe; Masahito Ebina; Akitoshi Ishizaka; Sachiko Tsukita; Satoru Hashimoto

  AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY AMER PHYSIOLOGICAL SOC 295 (4) L566 - L574 1040-0605 2008/10 [Refereed]
  
• Attenuated response to liver injury in moesin-deficient mice: Impaired stellate cell migration and decreased fibrosis

  Tokunari Okayama; Shojiro Kikuchi; Toshiya Ochiai; Hisashi Ikoma; Takeshi Kubota; Daisuke Ichikawa; Hitoshi Fujiwara; Kazuma Okamoto; Chouhei Sakakura; Teruhisa Sonoyama; Yukihito Kokuba; Yoshinori Doi; Sachiko Tsukita; D. Montgomery Bissell; Eigo Otsuji

  Biochimica et Biophysica Acta - Molecular Basis of Disease 1782 (9) 542 - 548 0925-4439 2008/09 [Refereed]
  
• ZO-1- and ZO-2-dependent integration of myosin-2 to epithelial zonula adherens

  Yuji Yamazaki; Kazuaki Umeda; Masami Wada; Shigeyuki Nada; Masato Okada; Shoichiro Tsukita; Sachiko Tsukita

  MOLECULAR BIOLOGY OF THE CELL AMER SOC CELL BIOLOGY 19 (9) 3801 - 3811 1059-1524 2008/09 [Refereed]
  
• Attenuated response to liver injury in moesin-deficient mice: impaired stellate cell migration and decreased fibrosis.

  Okayama T; Kikuchi S; Ochiai T; Ikoma H; Kubota T; Ichikawa D; Fujiwara H; Okamoto K; Sakakura C; Sonoyama T; Kokuba Y; Doi Y; Tsukita S; Bissell DM; Otsuji E

  Biochimica et biophysica acta 1782 (9) 542 - 548 0006-3002 2008/09 [Refereed]
  
• Recruitment of PCM1 to the centrosome by the cooperative action of DISC1 and BBS4 - A candidate for psychiatric illnesses

  Atsushi Kamiya; Perciliz L. Tan; Ken-ichiro Kubo; Caitlin Engelhard; Koko Ishizuka; Akiharu Kubo; Sachiko Tsukita; Ann E. Pulver; Kazunori Nakajima; Nicola G. Cascella; Nicholas Katsanis; Akira Sawa

  ARCHIVES OF GENERAL PSYCHIATRY AMER MEDICAL ASSOC 65 (9) 996 - 1006 0003-990X 2008/09 [Refereed]
  
• IQGAP3 regulates cell proliferation through the Ras/ERK signalling cascade

  Hisashi Nojima; Makoto Adachi; Takeshi Matsui; Katsuya Okawa; Shoichiro Tsukita; Sachiko Tsukita

  NATURE CELL BIOLOGY NATURE PUBLISHING GROUP 10 (8) 971 - 978 1465-7392 2008/08 [Refereed]
  
• ケラチン結合タンパク質Trichopleinの中心体における機能解析(Trichoplein, a keratin binding protein, is a functional component of centrosomes)

  衣斐 美歩; 鄒 鵬; 猪子 誠人; 大室 有紀[松山]; 米村 重信; 林 裕子; 森 大輔; 広常 真治; 田村 淳; 月田 早智子; 稲垣 昌樹

  日本細胞生物学会大会講演要旨集 (一社)日本細胞生物学会 60回 122 - 122 2008/06
• Deficiency of zonula occludens-1 causes embryonic lethal phenotype associated with defected yolk sac angiogenesis and apoptosis of embryonic cells

  Tatsuya Katsuno; Kazuaki Umeda; Takeshi Matsui; Masaki Hata; Atsushi Tamura; Masahiko Itoh; Kosei Takeuchi; Toshihiko Fujimori; Yo-ichi Nabeshima; Tetsuo Noda; Shoichiro Tsukita; Sachiko Tsukita

  MOLECULAR BIOLOGY OF THE CELL AMER SOC CELL BIOLOGY 19 (6) 2465 - 2475 1059-1524 2008/06 [Refereed]
  
• Optimized proteomic analysis on gels of cell-cell adhering junctional membrane proteins

  Yuji Yamazaki; Katsuya Okawa; Tomoki Yano; Shoichiro Tsukita; Sachiko Tsukita

  BIOCHEMISTRY AMER CHEMICAL SOC 47 (19) 5378 - 5386 0006-2960 2008/05 [Refereed]
  
• Megaintestine in claudin-15-deficient mice

  Atsushi Tamura; Yuka Kitano; Masaki Hata; Tatsuya Katsuno; Kazumasa Moriwaki; Hiroyuki Sasaki; Hisayoshi Hayashi; Yuichi Suzuki; Tetsuo Noda; Mikio Furuse; Shoichiro Tsukita; Sachiko Tsukita

  GASTROENTEROLOGY W B SAUNDERS CO-ELSEVIER INC 134 (2) 523 - 534 0016-5085 2008/02 [Refereed]
  
• Tight junctions containing claudin 4 and 6 are essential for blastocyst formation in preimplantation mouse embryos.

  Moriwaki K; Tsukita S; Furuse M

  Developmental biology 312 (2) 509 - 522 0012-1606 2007/12 [Refereed]
  
• 細胞間接着における細胞膜 細胞骨格のインターフェースとしてのZO-1

  勝野 達也; 梅田 一彰; 山崎 裕自; 三宅 由華; 和田 真実; 松井 毅; 田村 淳; 池ノ内 順一; 古瀬 幹夫; 月田 承一郎; 月田 早智子

  日本生化学会大会・日本分子生物学会年会合同大会講演要旨集 (公社)日本生化学会 80回・30回 4S15 - 3 2007/11
• Functional involvement of TMF/ARA160 in Rab6-dependent retrograde membrane traffic

  Junko Yamane; Akiharu Kubo; Kazuhisa Nakayama; Akiko Yuba-Kubo; Tatsuya Katsuno; Shoichiro Tsukita; Sachiko Tsukita

  EXPERIMENTAL CELL RESEARCH ELSEVIER INC 313 (16) 3472 - 3485 0014-4827 2007/10 [Refereed]
  
• 細胞間接着と細胞基質間接着とのクロストーク 上皮細胞極性化におけるベルト様adherens junctionとtight junctionの形成におけるZO-1の必要性(Requirement of ZO-1 for the formation of belt-like adherens junction and tight junction during epithelial cell polarization)

  池ノ内 順一; 梅田 一彰; 月田 早智子; 古瀬 幹夫; 月田 承一郎

  日本発生生物学会・日本細胞生物学会合同大会要旨集 日本発生生物学会・日本細胞生物学会 40回・59回 7 - 7 2007/05
• Effects of genetic backgrounds on hyperbilirubinemia in radixin-deficient mice due to different expression levels of Mrp3

  Kanehisa Fukumoto; Shojiro Kikuchi; Norio Itoh; Atsushi Tamura; Masaki Hata; Hisakazu Yamagishi; Shoichiro Tsukita; Sachiko Tsukita

  BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE ELSEVIER SCIENCE BV 1772 (3) 298 - 306 0925-4439 2007/03 [Refereed]
  
• Effects of genetic backgrounds on hyperbilirubinemia in radixin-deficient mice due to different expression levels of Mrp3.

  Fukumoto K; Kikuchi S; Itoh N; Tamura A; Hata M; Yamagishi H; Tsukita S; Tsukita S

  Biochimica et biophysica acta 1772 (3) 298 - 306 0006-3002 2007/03 [Refereed]
  
• Requirement of ZO-1 for the formation of belt-like adherens junctions during epithelial cell polarization

  Junichi Ikenouchi; Kazuaki Umeda; Sachiko Tsukita; Mikio Furuse; Shoichiro Tsukita

  JOURNAL OF CELL BIOLOGY ROCKEFELLER UNIV PRESS 176 (6) 779 - 786 0021-9525 2007/03 [Refereed]
  
• ZO-1 and ZO-2 independently determine where claudins are polymerized in tight-junction strand formation

  Kazuaki Umeda; Junichi Ikenouchi; Sayaka Katahira-Tayama; Kyoko Furuse; Hiroyuki Sasaki; Mayumi Nakayama; Takeshi Matsui; Sachiko Tsukita; Mikio Furuse; Shoichiro Tsukita

  CELL CELL PRESS 126 (4) 741 - 754 0092-8674 2006/08 [Refereed]
  
• Activated radixin is essential for GABA(A) receptor alpha 5 subunit anchoring at the actin cytoskeleton

  S Loebrich; R Bahring; T Katsuno; S Tsukita; M Kneussel

  EMBO JOURNAL NATURE PUBLISHING GROUP 25 (5) 987 - 999 0261-4189 2006/03 [Refereed]
  
• Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cells

  J Ikenouchi; M Furuse; K Furuse; H Sasaki; S Tsukita; S Tsukita

  JOURNAL OF CELL BIOLOGY ROCKEFELLER UNIV PRESS 171 (6) 939 - 945 0021-9525 2005/12 [Refereed]
  
• Odf2-deficient mother centrioles lack distal/subdistal appendages and the ability to generate primary cilia

  H Ishikawa; A Kubo; S Tsukita; S Tsukita

  NATURE CELL BIOLOGY NATURE PUBLISHING GROUP 7 (5) 517 - U79 1465-7392 2005/05 [Refereed]
  
• Achlorhydria by ezrin knockdown: defects in the formation/expansion of apical canaliculi in gastric parietal cells

  A Tamura; S Kikuchi; M Hata; T Katsuno; T Matsui; H Hayashi; Y Suzuki; T Noda; S Tsukita; S Tsukita

  JOURNAL OF CELL BIOLOGY ROCKEFELLER UNIV PRESS 169 (1) 21 - 28 0021-9525 2005/04 [Refereed]
  
• Radixin deficiency causes deafness associated with progressive degeneration of cochlear stereocilia

  S Kitajiri; K Fukumoto; M Hata; H Sasaki; T Katsuno; T Nakagawa; J Ito; S Tsukita; S Tsukita

  JOURNAL OF CELL BIOLOGY ROCKEFELLER UNIV PRESS 166 (4) 559 - 570 0021-9525 2004/08 [Refereed]
  
• Regulation of localization of transporters by ERM proteins

  S Tsukita

  YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN PHARMACEUTICAL SOC JAPAN 124 33 - 36 0031-6903 2004 [Refereed]
  
• Insights into a single rod-like helix in activated radixin required for membrane-cytoskeletal cross-linking

  KP Hoeflich; S Tsukita; L Hicks; CM Kay; S Tsukita; M Ikura

  BIOCHEMISTRY AMER CHEMICAL SOC 42 (40) 11634 - 11641 0006-2960 2003/10 [Refereed]
  
• Structural basis of adhesion-molecule recognition by ERM proteins revealed by the crystal structure of the radixin-ICAM-2 complex

  K Hamada; T Shimizu; S Yonemura; S Tsukita; S Tsukita; T Hakoshima

  EMBO JOURNAL OXFORD UNIV PRESS 22 (3) 502 - 514 0261-4189 2003/02 [Refereed]
  
• Radixin deficiency causes conjugated hyperbilirubinemia with loss of Mrp2 from bile canalicular membranes

  S Kikuchi; M Hata; K Fukumoto; Y Yamane; T Matsui; A Tamura; S Yonemura; H Yamagishi; D Keppler; S Tsukita; S Tsukita

  NATURE GENETICS NATURE PUBLISHING GROUP 31 (3) 320 - 325 1061-4036 2002/07 [Refereed]
  
• Rho-dependent and -independent activation mechanisms of ezrin/radixin/moesin proteins: an essential role for polyphosphoinositides in vivo

  S Yonemura; T Matsui; S Tsukita; S Tsukita

  JOURNAL OF CELL SCIENCE COMPANY OF BIOLOGISTS LTD 115 (12) 2569 - 2580 0021-9533 2002/06 [Refereed]
  
• Structural basis for neurofibromatosis type 2 - Crystal structure of the merlin FERM domain

  T Shimizu; A Seto; N Maita; K Hamada; S Tsukita; S Tsukita; T Hakoshima

  JOURNAL OF BIOLOGICAL CHEMISTRY AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC 277 (12) 10332 - 10336 0021-9258 2002/03 [Refereed]
  
• Structural conversion between open and closed forms of radixin: Low-angle shadowing electron microscopy

  H Ishikawa; A Tamura; T Matsui; H Sasaki; T Hakoshima; S Tsukita; S Tsukita

  JOURNAL OF MOLECULAR BIOLOGY ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD 310 (5) 973 - 978 0022-2836 2001/07 [Refereed]
  
• Outer dense fiber 2 is a widespread centrosome scaffold component preferentially associated with mother centrioles: Its identification from isolated centrosomes

  Y Nakagawa; Y Yamane; T Okanoue; S Tsukita; S Tsukita

  MOLECULAR BIOLOGY OF THE CELL AMER SOC CELL BIOLOGY 12 (6) 1687 - 1697 1059-1524 2001/06 [Refereed]
  
• Crystallization and preliminary crystallographic studies of RhoGDI in complex with the radixin FERM domain

  K Hamada; A Seto; T Shimizu; MB Takeshi; Y Takai; S Tsukita; S Tsukita; T Hakoshima

  ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY MUNKSGAARD INT PUBL LTD 57 (Pt 6) 889 - 890 0907-4449 2001/06 [Refereed]
  
• Crystallographic characterization of the radixin FERM domain bound to the cytoplasmic tail of the adhesion protein ICAM-2

  K Hamada; T Shimizu; T Matsui; S Tsukita; S Tsukita; T Hakoshima

  ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY MUNKSGAARD INT PUBL LTD 57 (Pt 6) 891 - 892 0907-4449 2001/06 [Refereed]
  
• Posttranscriptional regulation of alpha-catenin expression is required for Wnt signaling in L cells

  N Takahashi; S Ishihara; S Takada; S Tsukita; A Nagafuchi

  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS ACADEMIC PRESS INC 277 (3) 691 - 698 0006-291X 2000/11 [Refereed]
  
• Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain.

  Hamada K; Shimizu T; Matsui T; Tsukita S; Hakoshima T

  The EMBO journal 19 (17) 4449 - 4462 0261-4189 2000/09 [Refereed]
  
• Crystallographic characterization of the membrane-binding domain of radixin

  K Hamada; T Matsui; S Tsukita; S Tsukita; T Hakoshima

  ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY MUNKSGAARD INT PUBL LTD 56 (Pt 7) 922 - 923 0907-4449 2000/07 [Refereed]
  
• Structural basis of membrane targeting function of ERM proteins revealed by the crystal structures of the radixin FERM domain

  Hamada K.; Shimizu T.; Matsui T.; Tsukita S.; Tsukita S.; Hakoshima T.

  Seibutsu Butsuri The Biophysical Society of Japan General Incorporated Association 40 S120  0582-4052 2000
• The rabies virion-associated 100-kDa polypeptide (VAP100) is a host-derived minor component of the viral envelope

  S Xiao; K Komiya; TS Tochikura; J Sagara; S Tsukita; A Kawai

  MICROBIOLOGY AND IMMUNOLOGY CENTER ACADEMIC PUBL JAPAN 44 (8) 657 - 668 0385-5600 2000 [Refereed]
  
• Cortical actin organization: Lessons from ERM (ezrin/radixin/moesin) proteins

  S Tsukita; S Yonemura

  JOURNAL OF BIOLOGICAL CHEMISTRY AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC 274 (49) 34507 - 34510 0021-9258 1999/12 [Refereed]
  
• Activation of ERM proteins in vivo by Rho involves phosphatidylinositol 4-phosphate 5-kinase and not ROCK kinases

  T Matsui; S Yonemura; S Tsukita; S Tsukita

  CURRENT BIOLOGY CELL PRESS 9 (21) 1259 - 1262 0960-9822 1999/11 [Refereed]
  
• Expression level, subcellular distribution and Rho-GDI binding affinity of merlin in comparison with ezrin/radixin/moesin proteins

  M Maeda; T Matsui; M Imamura; S Tsukita; S Tsukita

  ONCOGENE STOCKTON PRESS 18 (34) 4788 - 4797 0950-9232 1999/08 [Refereed]
  
• Direct involvement of ezrin/radixin/moesin (ERM)-binding membrane proteins in the organization of microvilli in collaboration with activated ERM proteins

  S Yonemura; S Tsukita; S Tsukita

  JOURNAL OF CELL BIOLOGY ROCKEFELLER UNIV PRESS 145 (7) 1497 - 1509 0021-9525 1999/06 [Refereed]
  
• Immunofluorescence detection of ezrin/radixin/moesin (ERM) proteins with their carboxyl-terminal threonine phosphorylated in cultured cells and tissues - Application of a novel fixation protocol using trichloroacetic acid (TCA) as a fixative

  K Hayashi; S Yonemura; T Matsui; S Tsukita; S Tsukita

  JOURNAL OF CELL SCIENCE COMPANY OF BIOLOGISTS LTD 112 (8) 1149 - 1158 0021-9533 1999/04 [Refereed]
  
• Normal development of mice and unimpaired cell adhesion cell motility actin-based cytoskeleton without compensatory up-regulation of ezrin or radixin in moesin gene knockout

  Y Doi; M Itoh; S Yonemura; S Ishihara; H Takano; T Noda; S Tsukita; S Tsukita

  JOURNAL OF BIOLOGICAL CHEMISTRY AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC 274 (4) 2315 - 2321 0021-9258 1999/01 [Refereed]
  
• The FERM domain: a unique module involved in the linkage of cytoplasmic proteins to the membrane

  AH Chishti; AC Kim; SM Marfatia; M Lutchman; M Hanspal; H Jindal; SC Liu; PS Low; GA Rouleau; N Mohandas; JA Chasis; JG Conboy; P Gascard; Y Takakuwa; SC Huang; EJ Benz; A Bretscher; RG Fehon; AF Gusella; Ramesh, V; F Solomon; VT Marchesi; S Tsukita; S Tsukita; M Arpin; D Louvard; NK Tonks; JM Anderson; AS Fanning; PJ Bryant; DF Woods; KB Hoover

  TRENDS IN BIOCHEMICAL SCIENCES ELSEVIER SCI LTD 23 (8) 281 - 282 0968-0004 1998/08 [Refereed]
  
• Moesin is not a receptor for measles virus entry into mouse embryonic stem cells

  Y Doi; M Kurita; M Matsumoto; T Kondo; T Noda; S Tsukita; S Tsukita; T Seya

  JOURNAL OF VIROLOGY AMER SOC MICROBIOLOGY 72 (2) 1586 - 1592 0022-538X 1998/02 [Refereed]
  
• Ezrin/radixin/moesin (ERM) proteins bind to a positively charged amino acid cluster in the juxta-membrane cytoplasmic domain of CD44, CD43, and ICAM-2

  S Yonemura; M Hirao; Y Doi; N Takahashi; T Kondo; S Tsukita; S Tsukita

  JOURNAL OF CELL BIOLOGY ROCKEFELLER UNIV PRESS 140 (4) 885 - 895 0021-9525 1998/02 [Refereed]
  
• Rho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail association

  T Matsui; M Maeda; Y Doi; S Yonemura; M Amano; K Kaibuchi; S Tsukita; S Tsukita

  JOURNAL OF CELL BIOLOGY ROCKEFELLER UNIV PRESS 140 (3) 647 - 657 0021-9525 1998/02 [Refereed]
  
• Cytoplasmic regulation of the movement of E-cadherin on the free cell surface as studied by optical tweezers and single particle tracking: Corralling and tethering by the membrane skeleton

  Sako Y; Nagafuchi A; Tsukita S; Takeichi M; Kusumi A

  Journal of Cell Biology 140 (5) 1227 - 1240 1998 [Refereed]
  
• The 21-kDa polypeptide (VAP21) in the rabies virion is a CD99-related host cell protein

  J Sagara; TS Tochikura; H Tanaka; Y Baba; S Tsukita; S Tsukita; A Kawai

  MICROBIOLOGY AND IMMUNOLOGY CENTER ACADEMIC PUBL JAPAN 42 (4) 289 - 297 0385-5600 1998 [Refereed]
  
• ERM (ezrin/radixin/moesin)-based molecular mechanism of microvillar breakdown at an early stage of apoptosis

  T Kondo; K Takeuchi; Y Doi; S Yonemura; S Nagata; S Tsukita; S Tsukita

  JOURNAL OF CELL BIOLOGY ROCKEFELLER UNIV PRESS 139 (3) 749 - 758 0021-9525 1997/11 [Refereed]
  
• Direct interaction of the Rho GDP dissociation inhibitor with ezrin/radixin/moesin initiates the activation of the Rho small G protein

  K Takahashi; T Sasaki; A Mammoto; K Takaishi; T Kameyama; S Tsukita; S Tsukita; Y Takai

  JOURNAL OF BIOLOGICAL CHEMISTRY AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC 272 (37) 23371 - 23375 0021-9258 1997/09 [Refereed]
  
• ERM (ezrin/radixin/moesin) family: From cytoskeleton to signal transduction

  S Tsukita; S Yonemura; S Tsukita

  CURRENT OPINION IN CELL BIOLOGY CURRENT BIOLOGY LTD 9 (1) 70 - 75 0955-0674 1997/02 [Refereed]
  
• ERM proteins: Head-to-tail regulation of actin-plasma membrane interaction

  S Tsukita; S Yonemura; S Tsukita

  TRENDS IN BIOCHEMICAL SCIENCES ELSEVIER SCI LTD 22 (2) 53 - 58 0968-0004 1997/02 [Refereed]
  
• Immunological studies of a 21 kDa cellular component efficiently incorporated into rabies virion grown in a BHK-21 cell culture

  J Sagara; TS Tochikura; T Yamamoto; S Tsukita; S Tsukita; A Kawai

  MICROBIOLOGY AND IMMUNOLOGY CENTER ACADEMIC PUBL JAPAN 41 (12) 947 - 955 0385-5600 1997 [Refereed]
  
• Regulation mechanism of ERM (ezrin/radixin/moesin) protein/plasma membrane association: Possible involvement of phosphatidylinositol turnover and Rho-dependent signaling pathway

  M Hirao; N Sato; T Kondo; S Yonemura; M Monden; T Sasaki; Y Takai; S Tsukita; S Tsukita

  JOURNAL OF CELL BIOLOGY ROCKEFELLER UNIV PRESS 135 (1) 37 - 51 0021-9525 1996/10 [Refereed]
  
• Overexpression of occludin, a tight junction-associated integral membrane protein, induces the formation of intracellular multilamellar bodies bearing tight junction-like structures

  M Furuse; K Fujimoto; N Sato; T Hirase; S Tsukita; S Tsukita

  JOURNAL OF CELL SCIENCE COMPANY OF BIOLOGISTS LTD 109 429 - 435 0021-9533 1996/02 [Refereed]
  
• V-src kinase shifts the cadherin-based cell adhesion from the strong to the weak state and beta catenin is not required for the shift

  H Takeda; A Nagafuchi; S Yonemura; S Tsukita; J Behrens; W Birchmeier; S Tsukita

  JOURNAL OF CELL BIOLOGY ROCKEFELLER UNIV PRESS 131 (6) 1839 - 1847 0021-9525 1995/12 [Refereed]
  
• TRANSLOCATION OF ACTIVATED RHO FROM THE CYTOPLASM TO MEMBRANE RUFFLING AREA, CELL-CELL ADHESION SITES AND CLEAVAGE FURROWS

  K TAKAISHI; T SASAKI; T KAMEYAMA; S TSUKITA; S TSUKITA; Y TAKAI

  ONCOGENE STOCKTON PRESS 11 (1) 39 - 48 0950-9232 1995/07 [Refereed]
  
• CELLULAR ACTIN-BINDING EZRIN RADIXIN MOESIN (ERM) FAMILY PROTEINS ARE INCORPORATED INTO THE RABIES VIRION AND CLOSELY ASSOCIATED WITH VIRAL ENVELOPE PROTEINS IN THE CELL

  J SAGARA; S TSUKITA; S YONEMURA; S TSUKITA; A KAWAI

  VIROLOGY ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS 206 (1) 485 - 494 0042-6822 1995/01 [Refereed]
  
• DIRECT ASSOCIATION OF OCCLUDIN WITH ZO-1 AND ITS POSSIBLE INVOLVEMENT IN THE LOCALIZATION OF OCCLUDIN AT TIGHT JUNCTIONS

  M FURUSE; M ITOH; T HIRASE; A NAGAFUCHI; S YONEMURA; S TSUKITA; S TSUKITA

  JOURNAL OF CELL BIOLOGY ROCKEFELLER UNIV PRESS 127 (6) 1617 - 1626 0021-9525 1994/12 [Refereed]
  
• INDUCTION OF POLARIZED CELL-CELL ASSOCIATION AND RETARDATION OF GROWTH BY ACTIVATION OF THE E-CADHERIN CATENIN ADHESION SYSTEM IN A DISPERSED CARCINOMA LINE

  M WATABE; A NAGAFUCHI; S TSUKITA; M TAKEICHI

  JOURNAL OF CELL BIOLOGY ROCKEFELLER UNIV PRESS 127 (1) 247 - 256 0021-9525 1994/10 [Refereed]
  
• STRUCTURAL DIVERSITY OF BAND-4.1 SUPERFAMILY MEMBERS

  K TAKEUCHI; A KAWASHIMA; A NAGAFUCHI; S TSUKITA

  JOURNAL OF CELL SCIENCE COMPANY OF BIOLOGISTS LTD 107 1921 - 1928 0021-9533 1994/07 [Refereed]
  
• ERM FAMILY MEMBERS AS MOLECULAR LINKERS BETWEEN THE CELL-SURFACE GLYCOPROTEIN CD44 AND ACTIN-BASED CYTOSKELETONS

  S TSUKITA; K OISHI; N SATO; J SAGARA; A KAWAI; S TSUKITA

  JOURNAL OF CELL BIOLOGY ROCKEFELLER UNIV PRESS 126 (2) 391 - 401 0021-9525 1994/07 [Refereed]
  
• PERTURBATION OF CELL-ADHESION AND MICROVILLI FORMATION BY ANTISENSE OLIGONUCLEOTIDES TO ERM FAMILY MEMBERS

  K TAKEUCHI; N SATO; H KASAHARA; N FUNAYAMA; A NAGAFUCHI; S YONEMURA; S TSUKITA; S TSUKITA

  JOURNAL OF CELL BIOLOGY ROCKEFELLER UNIV PRESS 125 (6) 1371 - 1384 0021-9525 1994/06 [Refereed]
  
• A Truncated β-Catenin Disrupts the Interaction between E-Cadherin and α-Catenin: A Cause of Loss of Intercellular Adhesiveness in Human Cancer Cell Lines

  Oyama, T.; Kanai, Y.; Ochiai, A.; Akimoto, S.; Oda, T.; Yanagihara, K.; Nagafuchi, A.; Tsukita, S.; Shibamoto, S.; Ito, F.; Takeichi, M.; Matsuda, H.; Hirohashi, S.

  Cancer Research 54 (23) 1994 [Refereed]
  
• ASSIGNMENT OF THE HUMAN MOESIN GENE (MSN) TO CHROMOSOME REGION XQ11.2-]Q12

  T KISHINO; T ARIGA; H SOEJIMA; T TAMURA; T OHTA; Y JINNO; S YONEMURA; N SATO; S TSUKITA; S TSUKITA; Y SAKIYAMA; N NIIKAWA

  CYTOGENETICS AND CELL GENETICS KARGER 66 (3) 167 - 169 0301-0171 1994 [Refereed]
  
• POSSIBLE INVOLVEMENT OF ADHERENS JUNCTION PLAQUE PROTEINS IN TUMORIGENESIS AND METASTASIS

  S TSUKITA; S TSUKITA; A NAGAFUCHI; S YONEMURA

  MOLECULAR AND CELLULAR BASIS FOR CELL TO CELL INTERACTION: ITS SIGNIFICANCE IN CANCER PRINCETON SCIENTIFIC PUBL CO 24 38 - 50 1994 [Refereed]
  
• SUBMEMBRANOUS JUNCTIONAL PLAQUE PROTEINS INCLUDE POTENTIAL TUMOR-SUPPRESSOR MOLECULES

  S TSUKITA; M ITOH; A NAGAFUCHI; S YONEMURA; S TSUKITA

  JOURNAL OF CELL BIOLOGY ROCKEFELLER UNIV PRESS 123 (5) 1049 - 1053 0021-9525 1993/12 [Refereed]
  
• OCCLUDIN - A NOVEL INTEGRAL MEMBRANE-PROTEIN LOCALIZING AT TIGHT JUNCTIONS

  M FURUSE; T HIRASE; M ITOH; A NAGAFUCHI; S YONEMURA; S TSUKITA; S TSUKITA

  JOURNAL OF CELL BIOLOGY ROCKEFELLER UNIV PRESS 123 (6) 1777 - 1788 0021-9525 1993/12 [Refereed]
  
• DESMOYOKIN, A 680 KDA KERATINOCYTE PLASMA MEMBRANE-ASSOCIATED PROTEIN, IS HOMOLOGOUS TO THE PROTEIN ENCODED BY HUMAN GENE AHNAK

  T HASHIMOTO; M AMAGAI; DAD PARRY; TW DIXON; S TSUKITA; S TSUKITA; K MIKI; K SAKAI; Y INOKUCHI; J KUDOH; N SHIMIZU; T NISHIKAWA

  JOURNAL OF CELL SCIENCE COMPANY OF BIOLOGISTS LTD 105 275 - 286 0021-9533 1993/06 [Refereed]
  
• THE 220-KD PROTEIN COLOCALIZING WITH CADHERINS IN NONEPITHELIAL CELLS IS IDENTICAL TO ZO-1, A TIGHT JUNCTION ASSOCIATED PROTEIN IN EPITHELIAL-CELLS - CDNA CLONING AND IMMUNOELECTRON MICROSCOPY

  M ITOH; A NAGAFUCHI; S YONEMURA; T KITANIYASUDA; S TSUKITA; S TSUKITA

  JOURNAL OF CELL BIOLOGY ROCKEFELLER UNIV PRESS 121 (3) 491 - 502 0021-9525 1993/05 [Refereed]
  
• CONCENTRATION OF AN INTEGRAL MEMBRANE-PROTEIN, CD43 (LEUKOSIALIN, SIALOPHORIN), IN THE CLEAVAGE FURROW THROUGH THE INTERACTION OF ITS CYTOPLASMIC DOMAIN WITH ACTIN-BASED CYTOSKELETONS

  S YONEMURA; A NAGAFUCHI; N SATO; S TSUKITA

  JOURNAL OF CELL BIOLOGY ROCKEFELLER UNIV PRESS 120 (2) 437 - 449 0021-9525 1993/01
• A GENE FAMILY CONSISTING OF EZRIN, RADIXIN AND MOESIN - ITS SPECIFIC LOCALIZATION AT ACTIN FILAMENT PLASMA-MEMBRANE ASSOCIATION SITES

  N SATO; N FUNAYAMA; A NAGAFUCHI; S YONEMURA; S TSUKITA; S TSUKITA

  JOURNAL OF CELL SCIENCE COMPANY OF BIOLOGISTS LTD 103 131 - 143 0021-9533 1992/09 [Refereed]
  
• CADHERIN-MEDIATED CELL CELL-ADHESION IS PERTURBED BY V-SRC TYROSINE PHOSPHORYLATION IN METASTATIC FIBROBLASTS

  N MATSUYOSHI; M HAMAGUCHI; S TANIGUCHI; A NAGAFUCHI; S TSUKITA; M TAKEICHI

  JOURNAL OF CELL BIOLOGY ROCKEFELLER UNIV PRESS 118 (3) 703 - 714 0021-9525 1992/08 [Refereed]
  
• Molecular linkage between cadherins and actin filaments in cell-cell adherens junctions

  Shoichiro Tsukita; Sachiko Tsukita; Akira Nagafuchi; Shigenobu Yonemura

  Current Opinion in Cell Biology 4 (5) 834 - 839 0955-0674 1992 [Refereed]
  
• A 220-KD UNDERCOAT-CONSTITUTIVE PROTEIN - ITS SPECIFIC LOCALIZATION AT CADHERIN-BASED CELL CELL-ADHESION SITES

  M ITOH; S YONEMURA; A NAGAFUCHI; S TSUKITA; S TSUKITA

  JOURNAL OF CELL BIOLOGY ROCKEFELLER UNIV PRESS 115 (5) 1449 - 1462 0021-9525 1991/12 [Refereed]
  
• RADIXIN IS A NOVEL MEMBER OF THE BAND-4.1 FAMILY

  N FUNAYAMA; A NAGAFUCHI; N SATO; S TSUKITA; S TSUKITA

  JOURNAL OF CELL BIOLOGY ROCKEFELLER UNIV PRESS 115 (4) 1039 - 1048 0021-9525 1991/11 [Refereed]
  
• SPECIFIC PROTOONCOGENIC TYROSINE KINASES OF SRC FAMILY ARE ENRICHED IN CELL-TO-CELL ADHERENS JUNCTIONS WHERE THE LEVEL OF TYROSINE PHOSPHORYLATION IS ELEVATED

  S TSUKITA; K OISHI; T AKIYAMA; Y YAMANASHI; T YAMAMOTO; S TSUKITA

  JOURNAL OF CELL BIOLOGY ROCKEFELLER UNIV PRESS 113 (4) 867 - 879 0021-9525 1991/05 [Refereed]
  
• RADIXIN, A BARBED END-CAPPING ACTIN-MODULATING PROTEIN, IS CONCENTRATED AT THE CLEAVAGE FURROW DURING CYTOKINESIS

  N SATO; S YONEMURA; T OBINATA; S TSUKITA; S TSUKITA

  JOURNAL OF CELL BIOLOGY ROCKEFELLER UNIV PRESS 113 (2) 321 - 330 0021-9525 1991/04 [Refereed]
  
• LOCALIZATION OF ADHERENS JUNCTION PROTEINS ALONG THE POSSIBLE SLIDING INTERFACE BETWEEN SECRETORY AMELOBLASTS OF THE RAT INCISOR

  S NISHIKAWA; S TSUKITA; S TSUKITA; S SASA

  CELL STRUCTURE AND FUNCTION JAPAN SOC CELL BIOLOGY 15 (5) 245 - 249 0386-7196 1990/10 [Refereed]
  
• THE UNDERCOAT OF ADHERENS JUNCTIONS - A KEY SPECIALIZED STRUCTURE IN ORGANOGENESIS AND CARCINOGENESIS

  S TSUKITA; S TSUKITA; A NAGAFUCHI

  CELL STRUCTURE AND FUNCTION JAPAN SOC CELL BIOLOGY 15 (1) 7 - 12 0386-7196 1990/02 [Refereed]
  
• Molecular basis of actin-membrane interaction.

  TSUKITA Shoichiro; TSUKITA Sachiko

  Seibutsu Butsuri The Biophysical Society of Japan General Incorporated Association 30 (3) 127 - 132 0582-4052 1990
• A NEW 400-KD PROTEIN FROM ISOLATED ADHERENS JUNCTIONS - ITS LOCALIZATION AT THE UNDERCOAT OF ADHERENS JUNCTIONS AND AT MICROFILAMENT BUNDLES SUCH AS STRESS FIBERS AND CIRCUMFERENTIAL BUNDLES

  S TSUKITA; M ITOH; S TSUKITA

  JOURNAL OF CELL BIOLOGY ROCKEFELLER UNIV PRESS 109 (6) 2905 - 2915 0021-9525 1989/12 [Refereed]
  
• A NEW HIGH MOLECULAR MASS PROTEIN SHOWING UNIQUE LOCALIZATION IN DESMOSOMAL PLAQUE

  Y HIEDA; S TSUKITA; S TSUKITA

  JOURNAL OF CELL BIOLOGY ROCKEFELLER UNIV PRESS 109 (4) 1511 - 1518 0021-9525 1989/10 [Refereed]
  
• A NEW 82-KD BARBED END-CAPPING PROTEIN (RADIXIN) LOCALIZED IN THE CELL-TO-CELL ADHERENS JUNCTION - PURIFICATION AND CHARACTERIZATION

  S TSUKITA; Y HIEDA; S TSUKITA

  JOURNAL OF CELL BIOLOGY ROCKEFELLER UNIV PRESS 108 (6) 2369 - 2382 0021-9525 1989/06 [Refereed]
  
• ISOLATION OF CELL-TO-CELL ADHERENS JUNCTIONS FROM RAT-LIVER

  S TSUKITA; S TSUKITA

  JOURNAL OF CELL BIOLOGY ROCKEFELLER UNIV PRESS 108 (1) 31 - 41 0021-9525 1989/01 [Refereed]
  
• CLEAVAGE FURROW ISOLATED FROM NEWT EGGS - CONTRACTION, ORGANIZATION OF THE ACTIN-FILAMENTS, AND PROTEIN-COMPONENTS OF THE FURROW

  MABUCHI, I; S TSUKITA; S TSUKITA; T SAWAI

  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA NATL ACAD PRESS 85 (16) 5966 - 5970 0027-8424 1988/08 [Refereed]
  
• LIGHT-INDUCED STRUCTURAL-CHANGES OF CYTOSKELETON IN SQUID PHOTORECEPTOR MICROVILLI DETECTED BY RAPID-FREEZE METHOD

  S TSUKITA; S TSUKITA; G MATSUMOTO

  JOURNAL OF CELL BIOLOGY ROCKEFELLER UNIV PRESS 106 (4) 1151 - 1160 0021-9525 1988/04 [Refereed]
  
• Instantaneous view of actomyosin structure in shortening muscle.

  S. Tsukita; M. Yano

  Advances in experimental medicine and biology 226 31 - 38 0065-2598 1988
• CHARACTERISTIC STRUCTURES OF ACTIN GELS INDUCED WITH HEPATIC ACTINOGELIN OR WITH CHICKEN GIZZARD ALPHA-ACTININ - IMPLICATION FOR THEIR FUNCTION

  S TSUKITA; N MIMURA; S TSUKITA; K KHONO; T OHTAKI; T OSHIMA; H ISHIKAWA; A ASANO

  CELL MOTILITY AND THE CYTOSKELETON WILEY-LISS 10 (4) 451 - 463 0886-1544 1988 [Refereed]
  
• What Is an Informative Freeze-Substitution Image?

  Tsukita Shoichiro; Tsukita Sachiko

  kenbikyo The Japanese Society of Microscopy 21 (3) 219 - 222 0417-0326 1987
• Purification and properties of dihydrogeodin oxidase from Aspergillus terreus

  Isao Fujii; Hiroshi Iijima; Sachiko Tsukita; Yutaka Ebizuka; Ushio Sankawa

  Journal of Biochemistry Oxford University Press 101 (1) 11 - 18 0021-924X 1987 [Refereed]
  
• SUBAXOLEMMAL CYTOSKELETON IN SQUID GIANT-AXON .2. MORPHOLOGICAL IDENTIFICATION OF MICROTUBULE-ASSOCIATED AND MICROFILAMENT-ASSOCIATED DOMAINS OF AXOLEMMA

  S TSUKITA; S TSUKITA; T KOBAYASHI; G MATSUMOTO

  JOURNAL OF CELL BIOLOGY ROCKEFELLER UNIV PRESS 102 (5) 1710 - 1725 0021-9525 1986/05 [Refereed]
  
• SUBAXOLEMMAL CYTOSKELETON IN SQUID GIANT-AXON .1. BIOCHEMICAL-ANALYSIS OF MICROTUBULES, MICROFILAMENTS, AND THEIR ASSOCIATED HIGH-MOLECULAR-WEIGHT PROTEINS

  T KOBAYASHI; S TSUKITA; S TSUKITA; Y YAMAMOTO; G MATSUMOTO

  JOURNAL OF CELL BIOLOGY ROCKEFELLER UNIV PRESS 102 (5) 1699 - 1709 0021-9525 1986/05 [Refereed]
  
• INTERACTION OF ACTINOGELIN WITH ACTIN - NO NUCLEATION BUT HIGH GELATION ACTIVITY

  T OHTAKI; S TSUKITA; N MIMURA; S TSUKITA; A ASANO

  EUROPEAN JOURNAL OF BIOCHEMISTRY SPRINGER VERLAG 153 (3) 609 - 620 0014-2956 1985/12 [Refereed]
  
• DESMOCALMIN - A CALMODULIN-BINDING HIGH MOLECULAR-WEIGHT PROTEIN ISOLATED FROM DESMOSOMES

  S TSUKITA; S TSUKITA

  JOURNAL OF CELL BIOLOGY ROCKEFELLER UNIV PRESS 101 (6) 2070 - 2080 0021-9525 1985 [Refereed]
  
• BARBED END-CAPPING PROTEIN REGULATES POLARITY OF ACTIN-FILAMENTS FROM THE HUMAN-ERYTHROCYTE MEMBRANE

  S TSUKITA; S TSUKITA; H HOSOYA; MABUCHI, I

  EXPERIMENTAL CELL RESEARCH ELSEVIER INC 158 (1) 280 - 285 0014-4827 1985 [Refereed]
  
• ACTIN-MODULATING PROTEINS IN THE SEA URCHIN EGG .4. ALPHA-ACTININ FROM SEA-URCHIN EGGS - BIOCHEMICAL-PROPERTIES, INTERACTION WITH ACTIN, AND DISTRIBUTION IN THE CELL DURING FERTILIZATION AND CLEAVAGE

  MABUCHI, I; Y HAMAGUCHI; T KOBAYASHI; H HOSOYA; S TSUKITA; S TSUKITA

  JOURNAL OF CELL BIOLOGY ROCKEFELLER UNIV PRESS 100 (2) 375 - 383 0021-9525 1985 [Refereed]
  
• The role of ankyrin in shape and deformability change of human erythrocyte ghosts

  Yoshinori Jinbu; Shingo Sato; Toshiko Nakao; Makoto Nakao; Sachiko Tsukita; Shoichiro Tsukita; Harunori Ishikawa

  BBA - Biomembranes 773 (2) 237 - 245 0005-2736 1984/06 [Refereed]
  
• CA-2+-DEPENDENT AND MG-ATP-DEPENDENT SHAPE CHANGE OF HUMAN-ERYTHROCYTE GHOSTS AND TRITON SHELLS

  Y JINBU; S SATO; M NAKAO; S TSUKITA

  EXPERIMENTAL CELL RESEARCH ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS 151 (1) 160 - 170 0014-4827 1984 [Refereed]
  
• THE ROLE OF ANKYRIN IN SHAPE AND DEFORMABILITY CHANGE OF HUMAN-ERYTHROCYTE GHOSTS

  Y JINBU; S SATO; T NAKAO; M NAKAO; S TSUKITA; S TSUKITA; H ISHIKAWA

  BIOCHIMICA ET BIOPHYSICA ACTA ELSEVIER SCIENCE BV 773 (2) 237 - 245 0006-3002 1984 [Refereed]
  
• BIDIRECTIONAL POLYMERIZATION OF G-ACTIN ON THE HUMAN-ERYTHROCYTE MEMBRANE

  S TSUKITA; S TSUKITA; H ISHIKAWA

  JOURNAL OF CELL BIOLOGY ROCKEFELLER UNIV PRESS 98 (3) 1102 - 1110 0021-9525 1984 [Refereed]
  
• MONOMERIC AND TRIMERIC STRUCTURES OF ACTIVE NA,K-ATPASE IN C12E8 SOLUTION

  T NAKAO; T OHNO; M NAKAO; G MAEKI; S TSUKITA; H ISHIKAWA

  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS 113 (1) 361 - 367 0006-291X 1983 [Refereed]
  
• BINDING-SITES OF CALMODULIN AND ACTIN ON THE BRAIN SPECTRIN, CALSPECTIN

  S TSUKITA; S TSUKITA; H ISHIKAWA; M KUROKAWA; K MORIMOTO; K SOBUE; S KAKIUCHI

  JOURNAL OF CELL BIOLOGY ROCKEFELLER UNIV PRESS 97 (2) 574 - 578 0021-9525 1983 [Refereed]
  
• ASSOCIATION OF ACTIN AND 10 NM FILAMENTS WITH THE DENSE BODY IN SMOOTH-MUSCLE CELLS OF THE CHICKEN GIZZARD

  S TSUKITA; S TSUKITA; H ISHIKAWA

  CELL AND TISSUE RESEARCH SPRINGER VERLAG 229 (2) 233 - 242 0302-766X 1983 [Refereed]
  
• ATP-DEPENDENT STRUCTURAL-CHANGES OF THE OUTER DYNEIN ARM IN TETRAHYMENA CILIA - A FREEZE-ETCH REPLICA STUDY

  S TSUKITA; S TSUKITA; J USUKURA; H ISHIKAWA

  JOURNAL OF CELL BIOLOGY ROCKEFELLER UNIV PRESS 96 (5) 1480 - 1485 0021-9525 1983 [Refereed]
  
• Correlative biochemical and morphological studies of brain calspectin: A spectrin-like calmodulin-binding protein.

  Kakiuchi S; Sobue K; Kanda K; Morimoto K; Tsukita S; Tsukita S; Ishikawa H; Kurokawa M

  Biomed Res Biomedical Research Press 3 (4) 400 - 410 1982 [Refereed]
  
• MYOSIN-FILAMENTS IN SMOOTH-MUSCLE CELLS OF THE GUINEA-PIG TAENIA-COLI - A FREEZE-SUBSTITUTION STUDY

  S TSUKITA; S TSUKITA; J USUKURA; H ISHIKAWA

  EUROPEAN JOURNAL OF CELL BIOLOGY WISSENSCHAFTLICHE VERLAG MBH 28 (2) 195 - 201 0171-9335 1982 [Refereed]
  
• THE CYTOSKELETON IN MYELINATED AXONS - A FREEZE-ETCH REPLICA STUDY

  S TSUKITA; J USUKURA; S TSUKITA; H ISHIKAWA

  NEUROSCIENCE PERGAMON-ELSEVIER SCIENCE LTD 7 (9) 2135 - 2147 0306-4522 1982 [Refereed]
  
• ELECTRON-MICROSCOPIC STUDY OF REASSOCIATION OF SPECTRIN AND ACTIN WITH THE HUMAN-ERYTHROCYTE MEMBRANE

  S TSUKITA; S TSUKITA; H ISHIKAWA; S SATO; M NAKAO

  JOURNAL OF CELL BIOLOGY ROCKEFELLER UNIV PRESS 90 (1) 70 - 77 0021-9525 1981 [Refereed]
  
• CYTOSKELETAL NETWORK UNDERLYING THE HUMAN-ERYTHROCYTE MEMBRANE - THIN-SECTION ELECTRON-MICROSCOPY

  S TSUKITA; S TSUKITA; H ISHIKAWA

  JOURNAL OF CELL BIOLOGY ROCKEFELLER UNIV PRESS 85 (3) 567 - 576 0021-9525 1980 [Refereed]
  

MISC

• The tight-junction apical complex as a system which organizes the TJ and apical membrane

  月田早智子; 柏原宏香; 田中啓雄; 田中啓雄; 北又学; 月田和人; 月田和人; 白土玄; 鈴木浩也; DAY Timothy; 勝野達也; 田村淳; 田村淳  日本分子生物学会年会プログラム・要旨集(Web)  45th-  2022
• Claudin-3の結晶構造が明らかにするタイトジャンクション形態の決定要素

  中村駿; 中村駿; 入江克雅; 入江克雅; 田中啓雄; 田村淳; 月田早智子; 藤吉好則; 藤吉好則  日本細胞生物学会大会(Web)  71st-  2019
• Electron microscopic study of TJ-apical complex in epithelial cell sheets

  月田 早智子; 国本 晃司; 立石 和博; ヘラワテイ エリサ; 竹永 富妙子; 中山 彰吾; 矢野 智樹; 田村 淳; 井上 加奈子; 西田 倫希; 西 竜治; 保田 英洋  大阪大学超高圧電子顕微鏡センター年報  (47)  20  -24  2018
• Down-regulation of Claudin-1 demonstrates the pathology of atopic dermatitis

  山賀 康右; 徳増 玲太郎; 室田 浩之; 田村 淳; 片山 一朗; 月田 早智子  臨床免疫・アレルギー科 = Clinical immunology & allergology  67-  (6)  599  -605  2017/06
• 血管炎・その他の免疫疾患 皮膚限局の血管炎が重症化した際の抗モエシン抗体の推移について

  岡野 達郎; 竹内 そら; 相馬 良直; 鈴木 浩也; 月田 早智子; 石津 明洋; 鈴木 和男; 川上 民裕  アレルギー  66-  (4-5)  621  -621  2017/05
• タイトジャンクションによる上皮細胞間バリア機能：クローディンを軸とした生体システム構築

  鈴木浩也; 田中啓雄; 田村淳; 月田早智子  実験医学  2017/04  [Invited]
  
• RELATIONSHIP OF ANTI-PHOSPHATIDYLSERINE-PROTHROMBIN COMPLEX ANTIBODIES AND ANTI-MOESIN ANTIBODIES IN PATIENTS WITH POLYARTERITIS NODOSA

  Tamihiro Kawakami; Tatsuro Okano; Sora Takeuchi; Yoshinao Soma; Koya Suzuki; Sachiko Tsukita; Akihiro Ishizu; Kazuo Suzuki  RHEUMATOLOGY  56-  28  -28  2017/03
• Cell-cell adhesion

  Tomoki Yano; Sachiko Tsukita  Seikagaku  89-  (6)  830  -840  2017
• 皮膚動脈炎(皮膚型結節性多発動脈炎)難治症例における血中マーカーの検討

  岡野 達郎; 竹内 そら; 相馬 良直; 鈴木 浩也; 月田 早智子; 石津 明洋; 鈴木 和男; 川上 民裕  Journal of Environmental Dermatology and Cutaneous Allergology  10-  (4)  463  -463  2016/10
• 蝸牛におけるtricellulinの機能

  坂口 博史; 神谷 透; 宮下 武憲; 稲本 隆平; 徳増 玲太郎; 森 望; 月田 早智子; 久 育男  耳鼻咽喉科ニューロサイエンス  30-  8  -10  2016/05
• Claudin-3 is expressed in sweat glands and prevents the leakage of sweat

  K. Yamaga; H. Murota; A. Tamura; S. Tsukita; I. Katayama  JOURNAL OF INVESTIGATIVE DERMATOLOGY  136-  (5)  S120  -S120  2016/05
• 血管病研究の最新知見 抗モエシン抗体と皮膚動脈炎との関与 全身性結節性多発動脈炎へ移行が想定される症例に関して

  岡野 達郎; 竹内 そら; 相馬 良直; 鈴木 和男; 鈴木 浩也; 月田 早智子; 石津 明洋; 川上 民裕  脈管学  56-  (1)  13  -14  2016/02
• マウス気管多繊毛上皮細胞の繊毛基底小体の整列の長時間高解像度ライブイメージングシステムの確立

  加納初穂; 加納初穂; HERAWATI Elisa; 小西聡史; 立石和博; 矢野智樹; 千葉秀平; 田村淳; 月田早智子  日本分子生物学会年会プログラム・要旨集(Web)  39th-  2016
• Regulation of epithelial barrier function by a TJ-associated actin-binding protein.

  S. Konishi; M. Uji; T. Mizuno; K. Tateishi; H. Kanoh; T. Yano; A. Tamura; S. Tsukita  MOLECULAR BIOLOGY OF THE CELL  27-  2016
• TJ-MAP4 up-regulate MLC-phosphorylation by binding to MLC, ZO1 and tubulin at tight junction.

  H. Kanoh; T. Yano; M. Uji; A. Tamura; S. Tsukita  MOLECULAR BIOLOGY OF THE CELL  27-  2016
• タイトジャンクションをターゲットとした消化管疾患治療の可能性

  田村淳; 田中啓雄; 鈴木浩也; 月田早智子  G.I.Research  2015/12  [Invited]
  
• Calmin, a novel AJ components, crosslinks beta-catenin to F-actin independently of alpha-catenin

  T. Yano; Y. Yamazaki; S. Tsukita  MOLECULAR BIOLOGY OF THE CELL  26-  2015
• Analysis of the dynamic behavior of basal bodies in tracheal multiciliated cells

  E. Herawati; D. Taniguchi; H. Kanoh; K. Tateishi; T. Nishida; S. Ishihara; S. Tsukita  MOLECULAR BIOLOGY OF THE CELL  26-  2015
• Identification of Apical Cytoskeletal Networks Directly Under the Surface of Airway Epithelial Cells.

  K. Tateishi; T. Nishida; S. Tsukita  MOLECULAR BIOLOGY OF THE CELL  26-  2015
• Regulation of epithelial morphorgenesis by a tight junction (TJ)-apical complex.

  S. Tsukita; T. Yano; H. Kanoh; A. Tamura  MOLECULAR BIOLOGY OF THE CELL  25-  2014/12
• Loss of Occludin caused mucociliary clearance defect with reduced number of multiciliated cells in mouse.

  E. Herawati; H. Tanaka; K. Tateishi; A. Tamura; S. Tsukita  MOLECULAR BIOLOGY OF THE CELL  25-  2014/12
• 胆管細胞におけるイオン輸送体の膜発現及び機能制御におけるezrinの役割

  波多野 亮; 秋山 香織; 田村 淳; 細木 誠之; 丸中 良典; 上野 義之; Caplan Michael; 月田 早智子; 浅野 真司  日本生化学会大会プログラム・講演要旨集  87回-  [2T14p  -07]  2014/10
• Casein Kinase 2 (CK2) Inhibition Limits Damage-Induced and Immune-Mediated Colitis by Distinct Mechanisms

  Ekaterina A. Khramtsova; Guohua Liang; Christopher R. Weber; Atsushi Tamura; Le Shen; Sachiko Tsukita; Jerrold R. Turner  GASTROENTEROLOGY  146-  (5)  S80  -S80  2014/05
• タイトジャンクション蛋白tricellulinの内耳における機能

  神谷 透; 坂口 博史; 宮下 武憲; 稲本 隆平; 徳増 玲太郎; 田村 淳; 森 望; 月田 早智子; 久 育男  日本耳鼻咽喉科学会会報  117-  (4)  433  -433  2014/04
• Sophisticated role of tight junctional claudins in biological systems

  S. Tsukita  ACTA PHYSIOLOGICA  210-  46  -46  2014/03
• タイトジャンクション蛋白tricellulinの内耳における機能について

  神谷 透; 坂口 博史; 宮下 武憲; 稲本 隆平; 森 望; 月田 早智子; 久 育男  Otology Japan  23-  (4)  575  -575  2013/10
• Tricellulin欠損は蝸牛感覚有毛細胞の変性により重度難聴を引き起こす(Tricellulin deficiency causes severe hearing loss due to cochlear hair cell degeneration)

  神谷 透; 坂口 博史; 徳増 玲太郎; 久 育男; 宮下 武憲; 稲本 隆平; 山崎 裕自; 田村 淳; 月田 早智子; 森 望  日本生化学会大会プログラム・講演要旨集  86回-  1T11p  -05  2013/09
• Electron Crystallography of Euglenoid Four-Transmembrane Protein Revealed the Linear Polymerization by a Combination of Three-Ways of Intermolecular Interaction

  Hiroshi Suzuki; Yasuyuki Ito; Kazutoshi Tani; Yuji Yamazaki; Masami Uji; Katsuhiko Mineta; Sachiko Tsukita; Yoshinori Fujiyoshi  BIOPHYSICAL JOURNAL  104-  (2)  42A  -42A  2013/01
• Stomach-type claudin18-deficient mouse spontaneously develops chronic gastritis, and associated with a part of carcinogenesis

  K. Suzuki; A. Tamura; S. Tsukita  MOLECULAR BIOLOGY OF THE CELL  24-  2013
• Cingulin-mediated association of microtubules with tight junctions and its regulation by AMPK

  T. Yano; T. Matsui; A. Tamura; M. Uji; S. Tsukita  MOLECULAR BIOLOGY OF THE CELL  24-  2013
• Ezrinによる全身のリン,カルシウム代謝調節における役割について

  波多野亮; 瀬川博子; 田村淳; 向所賢一; 宮本賢一; 服部隆則; 杉原洋行; 月田早智子; 浅野真司  日本生化学会大会(Web)  85th-  2P-460 (WEB ONLY)  -460  2012/12
• 腎リン酸再吸収におけるEzrinの生理的役割について

  波多野亮; 田村淳; 瀬川博子; 松原光伸; 宮本賢一; 月田早智子; 浅野真司  生化学  84回-  ROMBUNNO.3P-0277  -0277  2011/09
• A novel anti-neutrophil antibody in serum of patients with MPO-ANCA-AAV

  Koya Suzuki; Tomokazu Nagao; Mituyo Itabashi; Ryuichi Sugamata; Yuji Yamazaki; Wako Yumura; Sachiko Tsukita  CLINICAL AND EXPERIMENTAL IMMUNOLOGY  164-  96  -96  2011/05
• Ezrinの腎リン酸再吸収における生理的役割

  波多野亮; 藤井詠子; 安倍真美; 田村淳; 月田早智子; 瀬川博子; 松原光伸; 浅野真司  日本薬学会年会要旨集  131st-  (3)  135  -135  2011/03
• Loss of basal feet on Odf2 deletion perturbs polarization of basal bodies.

  K. Kunimoto; Y. Yamazaki; T. Nishida; K. Shinohara; H. Ishikawa; T. Hasegawa; T. Okanoue; H. Hamada; T. Noda; A. Tamura; S. Tsukita; S. Tsukita  MOLECULAR BIOLOGY OF THE CELL  22-  2011
• Rac1を介したE‐cadherin転写制御因子としてのadherens junction構成タンパク質Tara/TRIOBP1の機能解析

  YANO TOMOKI; YAMAZAKI YUJI; ADACHI MAKOTO; OKAWA KATSUYA; FORT PHILIPPE; TSUKITA SHOICHIRO; TSUKITA SACHIKO  生化学  ROMBUNNO.2T10P-16  2011
• Effect of ezrin knockdown on the architecture of gastric epithelia

  Shinji Asano; Takahito Tetsui; Yuka Kobayakawa; Atsushi Tamura; Sachiko Tsukita; Kenichi Mukaisho; Takanori Hattori  FASEB JOURNAL  24-  2010/04
• Ezrin欠損マウス胎盤・胎児で減少するhypotaurineの胎盤におけるトランスポーター同定

  樋口 慧; 西村 友宏; 登美 斉俊; 若山 友彦; 田村 淳; 月田 早智子; 曽我 朋義; 崔 吉道; 中島 恵美  薬剤学: 生命とくすり  70-  (Suppl.)  116  -116  2010/04
• 新規クローディン候補遺伝子群の予測と機能推定

  峯田克彦; 山本康子; 山本康子; 田中啓雄; 山崎裕自; 斎藤邦明; 田村淳; 武内恒成; 遠藤俊徳; 月田早智子  生化学  2010
• The role of paracellular Na+ permeability for Na+ -coupled glucose absorption

  Hisayoshi Hayashi; Kenta Nozaki; Atsushi Tamura; Sachiko Tsukita; Yuichi Suzuki  JOURNAL OF PHYSIOLOGICAL SCIENCES  60-  S59  -S59  2010
• Rac-GEF-binding Tara builds E-cadherin/Ankyrin/Spectrin frameworks in the junctional circunferential ring.

  YANO TOMOKI; YAMAZAKI YUJI; ADACHI MAKOTO; OKAWA KATSUYA; TSUKITA SHOICHIRO; TSUKITA SACHIKO  生化学  ROMBUNNO.2P-695  2009/09
• Ezrinノックアウトによる胎児血および胎盤中生体物質濃度変化のメタボローム解析

  樋口 慧; 西村 友宏; 登美 斉俊; 若山 友彦; 田村 淳; 月田 早智子; 曽我 朋義; 崔 吉道; 中島 恵美  薬剤学: 生命とくすり  69-  (Suppl.)  161  -161  2009/04
• PARACELLULAR CHANNEL-LIKE ROLE OF CLAUDINS : KNOCKOUT-MICE ANALYSES

  Sachiko Tsukita; Atsushi Tamura; Shoichiro Tsukita  JOURNAL OF PHYSIOLOGICAL SCIENCES  59-  86  -86  2009
• ROLES OF ZO-1 AND ZO-2 IN THE FORMATION OF EPITHELIAL CELL-CELL JUNCTIONS AND PARACELLULAR TRANSPORT

  Yuji Yamazaki; Kazuaki Umeda; Masami Wada; Shoichiro Tsukita; Sachiko Tsukita  JOURNAL OF PHYSIOLOGICAL SCIENCES  59-  36  -36  2009
• THE SODIUM ABSORPTION ASSOCIATED WITH ACTIVE GLUCOSE ABSORPTION IN PERFUSED MOUSE JEJUNUM IN VIVO

  Kenta Nozaki; Hisayoshi Hayashi; Atsushi Tamura; Sachiko Tsukita; Yuichi Suzuki  JOURNAL OF PHYSIOLOGICAL SCIENCES  59-  248  -248  2009
• EFFECTS OF PROSTONES ON TIGHT JUNCTIONS

  Atsushi Tamura; Ryuji Ueno; Sachiko Tsukita  JOURNAL OF PHYSIOLOGICAL SCIENCES  59-  88  -88  2009
• Identification of novel ciliary proteins using microarray analyses of in vitro ciliogenesis

  A. Kubo; M. Amagai; S. Tsukita; S. Tsukita  JOURNAL OF INVESTIGATIVE DERMATOLOGY  128-  S97  -S97  2008/04
• ERM(Ezrin/Radixin/Moesin)タンパク質におけるタンパク質間相互作用 (タンパク質間相互作用)

  田村 淳; 月田 早智子  生体の科学  58-  (5)  448  -450  2007/09
• 妊娠経過に伴う胎盤のezrin発現レベルと局在の変動

  樋口 慧; 和田 真実; 崔 吉道; 巨勢 典子; 田村 淳; 月田 早智子; 若山 友彦; 中島 恵美  薬剤学: 生命とくすり  67-  (Suppl.)  403  -403  2007/05
• ラット胎盤における妊娠経過に伴うezrinの発現量及び局在変動とP-gpの細胞内局在化への関与

  和田 真実; 崔 吉道; 巨勢 典子; 田村 淳; 月田 早智子; 若山 友彦; 上家 潤一; 大槻 純男; 寺崎 哲也; 中島 恵美  日本薬学会年会要旨集  127年会-  (3)  122  -122  2007/03
• クローディン15ノックアウトマウスにおける小腸肥大化の解析

  田村淳; 北野由香; 秦正樹; 勝野達也; 森脇一将; 佐々木博之; 野田哲生; 古瀬幹夫; 月田承一郎; 月田早智子  生化学  2007
• タイトジャンクションに局在する2つの類似したPDZドメイン含有分子MUPP1とPatjの解析

  ADACHI MAKOTO; HAMAZAKI YOKO; KOBAYASHI YUKA; TSUKITA SACHIKO; FURUSE MIKIO; TSUKITA SHOICHIRO  生化学  2P-0396  2007
• 高ビリルビン血症の発症は遺伝的背景により左右される : radixin knockout miceにおけるトランスポーターの変動解析

  福本 兼久; 菊池 正二郎; 伊藤 範朗; 岡山 徳成; 小西 啓夫; 北川 昌洋; 落合 登志哉; 園山 輝久; 月田 早智子; 月田 承一郎; 山岸 久一  日本外科学会雑誌  107-  (2)  369  -369  2006/03
• Clarification of intracellular localization of CLP36 and ezrin in syncytiotroph oblast and their relevance to polar distribution of transporters in the placenta

  Yoshimichi Sai; Satomi Horieya; Masami Wada; Hisashi Iizasa; Noriko Kose; Emi Nakashima; Tomohiko Wakayama; Atsushi Tamura; Sachiko Tsukita; Kyeong-Eun Lee; Young-Sook Kang  DRUG METABOLISM REVIEWS  38-  63  -64  2006
• Ezrin ノックダウンマウスにおける無酸症の解析 : gastric pareital cell 機能不全について(胃・十二指腸25, 第60回日本消化器外科学会総会)

  菊池 正二郎; 田村 淳; 落合 登志哉; 岡山 徳成; 北川 昌洋; 小西 啓夫; 田儀 知之; 月田 承一郎; 月田 早智子; 山岸 久一  日本消化器外科学会雑誌  38-  (7)  1083  -1083  2005/07
• Achlorhydria by ezrin knockdown: defects in the formation/expansion of apical canaliculi in gastric parietal cells

  Atsushi Tamura; Shojiro Kitkuchi; Masaki Hata; Tatsuya Katsuno; Tetsuo Noda; Takeshi Matsui; Hisayoshi Hayashi; Yuichi Suzuki; Shoichiro Tsukita; Sachiko Tsukita  CELL STRUCTURE AND FUNCTION  30-  58  -58  2005/06
• Odf2/cenexin-deficient mother centrioles lack the distal/subdistal appendages and the ability to generate primary cilia

  Hiroaki Ishikawa; Akiharu Kubo; Shoichiro Tsukita; Sachiko Tsukita  CELL STRUCTURE AND FUNCTION  30-  56  -56  2005/06
• Radixin deficiency causes deafness associated with progressive degeneration of cochlear stereocilia

  Shin-ichiro Kitajiri; Kanehisa Fukumoto; Masaki Hata; Hiroyuki Sasaki; Takayuki Nakagawa; Tae Soo Kim; Juichi Ito; Shoichiro Tsukita; Sachiko Tsukita  CELL STRUCTURE AND FUNCTION  29-  32  -32  2004/05
• 樹状細胞によるT細胞活性化におけるERMファミリーの役割

  平野 聡; 横須賀 忠; 山崎 晶; 荒瀬 尚; 木村 弥生; 小原 收; 月田 早智子; 月田 承一郎; 斉藤 隆  日本免疫学会総会・学術集会記録  33-  94  -94  2003/11
• Junctional adhesion molecule (JAM) binds to PAR-3: a possible mechanism for the recruitment of PAR-3 to tight junctions

  M Itoh; H Sasaki; M Furuse; H Ozaki; T Kita; S Tsukita  MOLECULAR BIOLOGY OF THE CELL  12-  219A  -219A  2001/11
• Structural conversion between open and closed forms of radixin: Low-angle shadowing electron microscopy

  H Ishikawa; A Tamura; T Matsui; H Sasaki; T Hakoshima; S Tsukita; S Tsukita  MOLECULAR BIOLOGY OF THE CELL  12-  448A  -448A  2001/11
• Clostridium perfringens enterotoxin fragment removes specific Claudins from tight junction strands: Evidence for direct involvement of Claudins in tight junction barrier.

  Sonoda, N; Furuse, M; Sasaki, H; Yonemura, S; Katahira, J; Horiguchi, Y; Tsukita, S  J. Cell Biol.  147-  (1)  195  -204  1999
• ERMタンパク質のRhoによる機能制御--アクチンフイラメント-細胞膜相互作用における役割 (特集 細胞高次機能を司る役者たち--細胞骨格・細胞接着のダイナミズムとシグナル伝達)

  松井 毅; 月田 早智子  細胞工学  17-  (12)  1856  -1864  1998/12
• Rho-kinase phosphorylates a carboxy-terminal threonine of ERM proteins and regulates their head-to-tail association

  T Matsui; M Amano; K Kaibuchi; S Tsukita; S Tsukita  MOLECULAR BIOLOGY OF THE CELL  9-  364A  -364A  1998/11
• Regulation mechanism of ERM protein/plasma membrane interaction: Possible involvement of Rho-dependent signaling pathway.

  S Tsukita; M Hirao; T Kondo; S Yonemura; T Sasaki; Y Takai; S Tsukita  MOLECULAR BIOLOGY OF THE CELL  7-  3497  -3497  1996/12
• ERM family members bind to several membrane proteins at microvilli.

  S Yonemura; M Hirao; N Sato; S Tsukita; S Tsukita  MOLECULAR BIOLOGY OF THE CELL  7-  2258  -2258  1996/12
• MOLECULAR-BIOLOGY OF INTERCELLULAR-JUNCTIONS

  S TSUKITA; S TSUKITA; A NAGAFUCHI; S YONEMURA  SEIKAGAKU  67-  (4)  279  -289  1995/04
• ERM family members as molecular linkers between the cell surface glycoprotein CD44 and actin based cytoskeltons

  TSUKITA S.  J, Cell Biol.  120-  271  -335  1994
• RADIXIN-LIKE PROTEIN LOCALIZED IN THE CONTRACTILE RING

  N SATO; S TSUKITA; A NAGAFUCHI; T OBINATA; S TSUKITA  JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY  11-  (4)  359  -359  1990/08
• 細胞接着装置の分子構築(眼でみるペ-ジ-300-)

  月田 早智子; 月田 承一郎  代謝  26-  (3)  別3p  1989/03
• CLEAVAGE FURROW FROM NEWT EGGS - ISOLATION, CONTRACTION, ORGANIZATION OF ACTIN-FILAMENTS AND PROTEIN-COMPONENTS

  MABUCHI, I; S TSUKITA; S TSUKITA; T SAWAI  CELL MOTILITY AND THE CYTOSKELETON  10-  (1-2)  344  -345  1988
• STRUCTURAL-ANALYSIS OF THE CONTRACTILE RING OF THE SEA-URCHIN EGG

  S YONEMURA; S TSUKITA; S TSUKITA; MABUCHI, I  ZOOLOGICAL SCIENCE  4-  (6)  1033  -1033  1987/12
• A NEW HIGH MOLECULAR-WEIGHT PROTEIN LOCALIZED IN DESMOSOME

  Y HIEDA; S TSUKITA; S TSUKITA  CELL STRUCTURE AND FUNCTION  12-  (6)  709  -709  1987/12
• NEW PROTEINS UNDERLYING PLASMA-MEMBRANE OF ADHERENS JUNCTION-I

  S TSUKITA; S TSUKITA  CELL STRUCTURE AND FUNCTION  12-  (6)  655  -655  1987/12
• NEW PROTEINS UNDERLYING PLASMA-MEMBRANE OF ADHERENS JUNCTION-II

  S TSUKITA; S TSUKITA  CELL STRUCTURE AND FUNCTION  12-  (6)  655  -655  1987/12
• ELECTRON-MICROSCOPIC ANALYSIS OF SEA-URCHIN EGG CORTICES

  S YONEMURA; S TSUKITA; S TSUKITA; MABUCHI, I  ZOOLOGICAL SCIENCE  3-  (6)  1048  -1048  1986/12
• ELECTRON-MICROSCOPIC STUDY OF THE DESMOSOMAL MEMBRANE - A THIN-SECTION AND FREEZE-ETCH REPLICA STUDY

  S TSUKITA; S TSUKITA  CELL STRUCTURE AND FUNCTION  11-  (4)  474  -474  1986/12
• CLEAVAGE FURROW ISOLATED FROM NEWT EGGS .3. CYTOSKELETAL PROTEINS AND EFFECTS OF INHIBITORS ON THE REACTIVATION

  MABUCHI, I; S TSUKITA; S TSUKITA; T SAWAI  CELL STRUCTURE AND FUNCTION  11-  (4)  479  -479  1986/12
• STRUCTURAL-CHANGES OF CORTICAL CYTOSKELETON OF THE SEA-URCHIN EGG DURING FERTILIZATION AND CLEAVAGE

  S YONEMURA; MABUCHI, I; S TSUKITA; S TSUKITA  CELL STRUCTURE AND FUNCTION  11-  (4)  479  -479  1986/12
• 中間径フィラメントとデスモソ-ム (中間径フィラメント<特集>)

  月田 早智子; 月田 承一郎  生体の科学  37-  (5)  p460  -468  1986/10
• DESMOCALMIN, A CALMODULIN-BINDING HIGH-MOLECULAR-WEIGHT PROTEIN ISOLATED FROM DESMOSOMES - BIOCHEMICAL-PROPERTIES, INTERACTION WITH KERATIN FILAMENTS, AND DISTRIBUTION IN THE EPITHELIAL-CELLS

  S TSUKITA; S TSUKITA  CELL STRUCTURE AND FUNCTION  10-  (4)  546  -546  1985/12
• CLEAVAGE FURROW ISOLATED FROM NEWT EGGS .1. PROTEIN CONSTITUENTS AND REACTIVATION

  MABUCHI, I; T SAWAI; S TSUKITA; S TSUKITA  CELL STRUCTURE AND FUNCTION  10-  (4)  542  -542  1985/12
• CLEAVAGE FURROW ISOLATED FROM NEWT EGGS .2. ULTRASTRUCTURE

  S TSUKITA; S TSUKITA; T SAWAI; MABUCHI, I  CELL STRUCTURE AND FUNCTION  10-  (4)  542  -542  1985/12
• NEW MICROTUBULE-ASSOCIATED PROTEINS - MAP-X AND AXOLININ

  T KOBAYASHI; S TSUKITA; S TSUKITA; G MATSUMOTO  CELL STRUCTURE AND FUNCTION  10-  (4)  533  -533  1985/12
• THE CYTOSKELETONS UNDERLYING THE EXCITABLE MEMBRANE OF SQUID GIANT-AXONS - FREEZE-ETCH REPLICA AND IMMUNOELECTRON MICROSCOPIC STUDY

  S TSUKITA; S TSUKITA; T KOBAYASHI; T ARAI; G MATSUMOTO  CELL STRUCTURE AND FUNCTION  10-  (4)  529  -529  1985/12
• ACTINOGELIN-INDUCED GELATION OF ACTIN-FILAMENTS - MORPHOLOGICAL AND BIOCHEMICAL-STUDIES

  S TSUKITA; T OHTAKI; N MIMURA; T OSHIMA; S TSUKITA; A ASANO  CELL STRUCTURE AND FUNCTION  10-  (4)  526  -526  1985/12
• THE CYTOSKELETON UNDERLYING PLASMA-MEMBRANE OF RHABDOMERAL MICROVILLI OF SQUID PHOTORECEPTORS

  S TSUKITA; S TSUKITA; G MATSUMOTO  CELL STRUCTURE AND FUNCTION  10-  (4)  528  -528  1985/12
• NEW MICROTUBULE-ASSOCIATED PROTEINS - MAP-X AND AXOLININ

  T KOBAYASHI; S TSUKITA; S TSUKITA; G MATSUMOTO  ZOOLOGICAL SCIENCE  2-  (6)  918  -918  1985
• FREEZE-ETCH REPLICA STUDY OF THE OUTER DYNEIN ARM IN CILIA

  S TSUKITA; S TSUKITA; H ISHIKAWA  CELL MOTILITY AND THE CYTOSKELETON  5-  (2)  146  -146  1985
• PROPERTIES OF THE CLEAVAGE FURROW ISOLATED FROM NEWT EGGS

  MABUCHI, I; S TSUKITA; S TSUKITA; T SAWAI  ZOOLOGICAL SCIENCE  2-  (6)  949  -949  1985
• PURIFICATION AND CHARACTERIZATION OF THE 3 COMPONENTS OF HIGH-MOLECULAR WEIGHT MICROTUBULE-ASSOCIATED PROTEINS FROM RAT-BRAIN

  T KOBAYASHI; S TSUKITA; S TSUKITA; G MATSUMOTO  ZOOLOGICAL SCIENCE  1-  (6)  914  -914  1984
• High molecular weight cytoskeletal proteins in squid giant axon

  Kobayashi Takaaki; Tsukita Sachiko; Tsukita Shoichiro; Matsumoto Gen; Yamamoto Yoshio  動物学雑誌  92-  (4)  566  -566  1983
• A 95Kd protein from sea urchin eggs that gels actin

  Mabuchi Issei; Kobayashi Takaaki; Hosoyam Hiroshi; Tsukita Sachiko; Tsukita Shoichiro  動物学雑誌  92-  (4)  567  -567  1983
• A SPECTRIN-LIKE PROTEIN FROM ISOLATED DESMOSOMES

  S TSUKITA; S TSUKITA  CELL STRUCTURE AND FUNCTION  8-  (4)  452  -452  1983
• MORPHOLOGICAL-STUDY ON THE TRANSFORMATION OF RAT FIBROBLAST BY ONCOGENE OF ADENO TYPE-12 VIRUS

  H YORIFUJI; K SHIROKI; H ISHIKAWA; S TSUKITA; S TSUKITA  CELL STRUCTURE AND FUNCTION  8-  (4)  444  -444  1983
• A FREEZE-ETCH REPLICA STUDY OF MUSCLE-CONTRACTION II

  S TSUKITA; M YANO; S TSUKITA; H TANAKA; H ISHIKAWA; H SHIMIZU  CELL STRUCTURE AND FUNCTION  8-  (4)  418  -418  1983
• A HIGH MOLECULAR-WEIGHT PROTEIN IN AXOPLASM UNDERLYING EXCITABLE MEMBRANE OF SQUID GIANT-AXON

  S TSUKITA; S TSUKITA; T KOBAYASHI; G MATSUMOTO  BIOMEDICAL RESEARCH-TOKYO  4-  (6)  615  -618  1983
• HIGH MOLECULAR-WEIGHT PROTEIN IN AXOPLASM UNDERLYING EXCITABLE MEMBRANE IN SQUID GIANT-AXON

  S TSUKITA; S TSUKITA; T KOBAYASHI; G MATSUMOTO  CELL STRUCTURE AND FUNCTION  8-  (4)  411  -411  1983
• BINDING-SITES OF CALMODULIN AND ACTIN ON THE BRAIN SPECTRIN

  S TSUKITA; S TSUKITA; H ISHIKAWA  JOURNAL OF ELECTRON MICROSCOPY  32-  (3)  244  -245  1983
• EFFECTS OF ADENYLYLIMIDODIPHOSPHATE ON THE STRUCTURE OF THE OUTER DYNEIN ARM IN TETRAHYMENA CILIA - A FREEZE-ETCH REPLICA STUDY

  S TSUKITA; S TSUKITA; H ISHIKAWA  BIOMEDICAL RESEARCH-TOKYO  4-  (3)  337  -340  1983
• MOLECULAR-STRUCTURE OF ACTINOGELIN

  S TSUKITA; S TSUKITA; H ISHIKAWA; T OHTAKI; N MIMURA; A ASANO  CELL STRUCTURE AND FUNCTION  8-  (4)  408  -408  1983
• ROLE OF ANKYRIN IN SHAPE AND DEFORMABILITY CHANGE OF HUMAN-ERYTHROCYTE GHOSTS

  Y JINBU; S SATO; T NAKAO; M NAKAO; S TSUKITA; S TSUKITA; H ISHIKAWA  CELL STRUCTURE AND FUNCTION  8-  (4)  412  -412  1983
• CALSPECTIN (SPECTRIN-LIKE CALMODULIN-BINDING PROTEIN) .1. PURIFICATION AND CHARACTERIZATION

  K MORIMOTO; K KANDA; K SOBUE; S KAKIUCHI; S TSUKITA; S TSUKITA; H ISHIKAWA; M KUROKAWA  NEUROCHEMICAL RESEARCH  8-  (6)  780  -780  1983
• SPECTRIN-LIKE CALMODULIN-BINDING PROTEIN (CALSPECTIN) .1. PURIFICATION AND ITS FUNCTION

  S KAKIUCHI; K SOBUE; S TSUKITA; S TSUKITA; H ISHIKAWA  CELL STRUCTURE AND FUNCTION  7-  (4)  378  -378  1982
• ATP-DEPENDENT STRUCTURAL-CHANGES OF THE OUTER DYNEIN ARM IN TETRAHYMENA CILIA - A FREEZE-ETCH REPLICA STUDY

  S TSUKITA; S TSUKITA; J USUKURA; H ISHIKAWA  CELL STRUCTURE AND FUNCTION  7-  (4)  385  -385  1982
• SPECTRIN-LIKE CALMODULIN-BINDING PROTEIN (CALSPECTIN) .2. MOLECULAR-STRUCTURE

  S TSUKITA; S TSUKITA; H ISHIKAWA; K SOBUE; S KAKIUCHI  CELL STRUCTURE AND FUNCTION  7-  (4)  378  -378  1982
• FREEZE-SUBSTITUTION STUDY ON MYOSIN-FILAMENTS IN SMOOTH-MUSCLE CELLS OF GUINEA-PIG TAENIA-COLI

  S TSUKITA; S TSUKITA; J USUKURA; H ISHIKAWA  JOURNAL OF ELECTRON MICROSCOPY  31-  (3)  313  -313  1982
• QUICK-FREEZE, DEEP-ETCH, REPLICA STUDY ON AXONAL CYTOSKELETON

  S TSUKITA; J USUKURA; S TSUKITA; H ISHIKAWA  JOURNAL OF ELECTRON MICROSCOPY  30-  (3)  263  -263  1981
• THE ARRANGEMENT OF ACTIN-FILAMENTS IN CHICKEN GIZZARD SMOOTH-MUSCLE

  S TSUKITA; S TSUKITA; H ISHIKAWA  CELL STRUCTURE AND FUNCTION  6-  (4)  422  -422  1981
• THE PLASMALEMMAL UNDERCOAT - AN ULTRASTRUCTURAL SIMILARITY AMONG VARIOUS SUB-MEMBRANOUS DENSITIES

  H ISHIKAWA; S TSUKITA; S TSUKITA  EUROPEAN JOURNAL OF CELL BIOLOGY  22-  (1)  338  -338  1980
• RECONSTITUTION AND FUNCTION OF THE HUMAN-ERYTHROCYTE CYTOSKELETON

  S TSUKITA; S TSUKITA; H ISHIKAWA  CELL STRUCTURE AND FUNCTION  5-  (4)  424  -424  1980
• ELECTRON-MICROSCOPE OBSERVATIONS ON INSITU AND RECONSTITUTED CYTOSKELETAL NETWORKS UNDERLYING HUMAN-ERYTHROCYTE MEMBRANES

  S TSUKITA; S TSUKITA; H ISHIKAWA; S SATO; M NAKAO  EUROPEAN JOURNAL OF CELL BIOLOGY  22-  (1)  338  -338  1980
• ULTRASTRUCTURAL ANALYSIS OF THE CYTOSKELETAL NETWORK UNDERLYING THE HUMAN-ERYTHROCYTE MEMBRANE

  S TSUKITA; S TSUKITA; H ISHIKAWA  JOURNAL OF ELECTRON MICROSCOPY  29-  (3)  279  -280  1980

Awards & Honors

• 2015/03 東レ科学技術財団 東レ科学賞
   

  受賞者: 月田 早智子
• 2014/07 大阪大学 総長顕彰（研究部門）
   

  受賞者: 月田 早智子
• 2013/08 大阪大学 総長顕彰（研究部門）
   

  受賞者: 月田 早智子
• 2012/04 文部科学省 文部科学大臣表彰科学技術賞（研究部門）
   

  受賞者: 月田 早智子
• 1988/05 日本電子顕微鏡学会 瀬藤賞
   

  受賞者: 月田 早智子

Research Grants & Projects

• Novel approach focusing on the tight junction-based paracellular barrier combined with the apical barrier toward understanding and manipulating epithelial barriers

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 2019/04 -2024/03 

  Author : 月田 早智子; 田村 淳; Danev Radostin; 後藤 慎平; 田中 啓雄; 中村 駿; 柏原 宏香; 足立 誠; 鈴木 貴; 矢野 智樹; 入江 克雅
• 上皮バリアの構築と機能を制御するタイトジャンクション・アピカル複合体の解析

  日本学術振興会：科学研究費助成事業

  Date (from‐to) : 2018/04 -2020/03 

  Author : 月田 早智子; 勝野 達也
• The establishment of intercellular co-ordination of ciliary movement by using human iPS cell-derived airway epithelial cells

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 2017/04 -2019/03 

  Author : Konishi Satoshi; Tsukita Sachiko; Gotoh Shimpei
• The role of apical cytoskeletons in transition between centrosomes and ciliary basal bodies.

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 2012/06 -2017/03 

  Author : Tsukita Sachiko; YAMAZAKI Yuji; TAMURA Atsushi
• Cilium-centrosome system regulating biosignal flows

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 2012/06 -2017/03 

  Author : Hamada Hiroshi; KITAGAWA Daiju; HIROTSUNE Shinji; KIKKAWA Masahide; SUGIMOTO Asako; TOYOSHIMA Fumiko
• How reciprocal regulation of the cell-cell adhesion and the apical membrane defines a unified epithelial system via the cytoskeleton and cell signaling in epithelial cell sheets

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 2012/04 -2016/03 

  Author : Tsukita Sachiko; Yamazaki Yuji; TAMURA Atsushi; Takeuchi Kosei; Mineta Katsuhiko; Ito Masahiko
• がん微小環境制御因子としての細胞間バリアーの役割

  日本学術振興会：科学研究費助成事業

  Date (from‐to) : 2011 -2012 

  Author : 月田 早智子
• Generation of claudin targeted autoimmune disease mouse model

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 2011 -2012 

  Author : TSUKITA Sachiko
• A novel approach to cell adhesion/cytoskeleton research for exploring the epithelia cell system

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 2007 -2012 

  Author : TSUKITA Sachiko; MATSUI Takeshi; SASAKI Hiroyuki; TAKEUCHI Kosei; YAMAZAKI Yuji; TAMURA Atsushi
• 細胞接着関連因子による上皮細胞間バリアーの形成とバリアー内イオンチャンネル形成機構

  日本学術振興会：科学研究費助成事業

  Date (from‐to) : 2008 -2009 

  Author : 月田 早智子; 田村 淳
• 炎症/発癌の下地形成における上皮細胞間バリアー機能不全

  日本学術振興会：科学研究費助成事業

  Date (from‐to) : 2008 -2009 

  Author : 月田 早智子; 田村 淳
• Molecular mechanisms of cell-cell adhesion in cancer cells

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 2005 -2009 

  Author : FURUSE Mikio; TSUKITA Sachiko; ADACHI Makoto; KUBO Akiharu; TAMURA Atsushi; ODA Yukako; SASAKI Hiroyuki
• Study on a new assay for the function of mammalian spenn centrosome

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 2007 -2008 

  Author : ITO Chizuru; TOSHIMORI Kiyotaka; TOYOTA Fumie; TOYAMA Yoshiro; MAEKAWA Mamiko; KAMIMURA Kyoko; MUTOH Tohru; YOSHIDA Keiichi; YAMATOYA Kenji; HARANO Masahiko; TSUKITA Sachiko; NODA Tetsuo; YAO Ryoji; AKUTSU Hidenori; MIYADO Kenji
• 上皮細胞における膜インターフェイスとしての細胞間接着関連分子群

  日本学術振興会：科学研究費助成事業

  Date (from‐to) : 2007 -2008 

  Author : 月田 早智子; 田村 淳; 佐々木 博之
• 上皮細胞の増殖を制御する細胞間接着装置・アピカル膜複合体の役割

  日本学術振興会：科学研究費助成事業

  Date (from‐to) : 2007 -2007 

  Author : 月田 早智子
• ERM proteins and Odf2 as organizers for apical membranes

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 2005 -2006 

  Author : TSUKITA Sachiko
• ERM proteins as integrators at the cell cortex : Gene knockout study

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 2003 -2004 

  Author : TSUKITA Sachiko
• Molecular mechanism for cell-cell adhesion in canceration and metastasis

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 2000 -2004 

  Author : TSUKITA Shoichiro; FURUSE Mikio; KUBO Akiharu; ADACHI Makoto; TSUKITA Sachiko
• Radixin deficiency causes conjugated hyperbilirubinemia with loss of Mrp2 from bile canalicular membranes

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 2001 -2002 

  Author : TSUKITA Sachiko
• CLAUDINS AND OCCLUDIN : COMPARISON WITH CONNEXIN

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 1999 -2000 

  Author : TSUKITA Shoichiro; NAGAFUCHI Akira; ITOH Masahiko; FURUSE Mikio; TSUKITA Sachiko; YONEMURA Shioenobu
• ERM PROTEIN-BASED MOLECULAR MECHANISM UNDERLYING THE REGULATION OF CELLULAR MORPHOGENESIS AND PROLIFERATION

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 1999 -2000 

  Author : TSUKITA Sachiko
• 細胞接着の異常と発がん・転移機構

  日本学術振興会：科学研究費助成事業

  Date (from‐to) : 1999 -1999 

  Author : 月田 承一郎; 月田 早智子; 米村 重信; 永渕 昭良; 伊藤 雅彦
• 間期細胞核に構造的極性はあるか?:上皮細胞の極性との関係

  日本学術振興会：科学研究費助成事業

  Date (from‐to) : 1998 -1999 

  Author : 月田 早智子
• Development of a new drug delivery method by the use of occludin molecules

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 1998 -1999 

  Author : TSUKITA Shoichiro; ITOH Masahiko; FURUSE Mikio; TSUKITA Sachiko
• βカテニンの分解によるシグナル伝達機構

  日本学術振興会：科学研究費助成事業

  Date (from‐to) : 1998 -1998 

  Author : 永渕 昭良; 月田 早智子; 古瀬 幹夫
• ERM proteins : from cytoskeleton to signal transduction

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 1997 -1998 

  Author : TSUKITA Sachiko
• Structure and function of occludin in tight junctions : comparison with connexin gap junctions

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 1997 -1998 

  Author : TSUKITA Shoichiro; ITOH Masahiko; TSUKITA Sachiko; KUMAR Narlin; GILULA Norton; FURUSE Mikio
• スキルス胃癌モデルマウスの開発

  日本学術振興会：科学研究費助成事業

  Date (from‐to) : 1995 -1996 

  Author : 永渕 昭良; 月田 早智子
• CD44-ERM-ACTIN SYSTEM,SIGNAL TRANSDUCTION,AND APOPTOSIS

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 1995 -1996 

  Author : TSUKITA Sachiko
• 上皮細胞分化における細胞接着関連蛋白質の役割:ダブルノックアウトES細胞を用いた解析

  日本学術振興会：科学研究費助成事業

  Date (from‐to) : 1995 -1995 

  Author : 永渕 昭良; 月田 早智子
• RhoのターゲットとしてのCD44ERM-アクチンシステム

  日本学術振興会：科学研究費助成事業

  Date (from‐to) : 1995 -1995 

  Author : 月田 早智子
• 細胞間接着による細胞増殖・分化の制御:ES細胞を用いた実験的アプローチ

  日本学術振興会：科学研究費助成事業

  Date (from‐to) : 1995 -1995 

  Author : 月田 早智子; 永渕 昭良
• RhoのターゲットとしてのCD44-ERM-アクチン・システム

  日本学術振興会：科学研究費助成事業

  Date (from‐to) : 1994 -1994 

  Author : 月田 早智子
• 細胞感接着による細胞増殖・分化の制御:ES細胞を用いた実験的アプローチ

  日本学術振興会：科学研究費助成事業

  Date (from‐to) : 1994 -1994 

  Author : 月田 早智子
• Plasma membrane-Actin filament Association through ERM Family Members

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 1993 -1994 

  Author : TSUKITA Sachiko
• Direct Measurement of Cell-Cell Adhesion

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 1993 -1994 

  Author : YONEMURA Sigenobu; NAGAFUCHI Akira; TSUKITA Sachiko
• 細胞間接着による細部増殖・分化の制御:ES細胞を開いた実験的アプローチ

  日本学術振興会：科学研究費助成事業

  Date (from‐to) : 1993 -1993 

  Author : 月田 早智子; 永渕 昭良
• 接着分子カドヘリンを介した内皮細胞間接着の制作機構

  日本学術振興会：科学研究費助成事業

  Date (from‐to) : 1993 -1993 

  Author : 月田 承一郎; 月田 早智子; 永淵 昭良
• 細胞間接着と発がん・転移機構

  日本学術振興会：科学研究費助成事業

  Date (from‐to) : 1993 -1993 

  Author : 月田 承一郎; 米村 重信; 月田 早智子; 永淵 昭良
• Time-lapse Electron Microscopy with Caged Compounds

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 1992 -1993 

  Author : TSUKITA Shoichiro; YONEMURA Shigenobu; TSUKITA Sachiko
• 細胞がん化における蛋白質リン酸化

  日本学術振興会：科学研究費助成事業

  Date (from‐to) : 1991 -1993 

  Author : 秋山 徹; 入江 賢児; 西田 栄介; 月田 早智子; 松田 覚; 野島 博
• 細胞癌における蛋白質リン酸化

  日本学術振興会：科学研究費助成事業

  Date (from‐to) : 1991 -1993 

  Author : 秋山 徹; 野島 博; 月田 早智子; 高橋 雅英; 松田 覚; 西田 栄介
• Molecular Anatomy on Intercellular Junctions

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 1991 -1993 

  Author : TSUKITA Shigenobu; NAGAFUCHI Akira; TSUKITA Sachiko; YONEMURA Shigenobu
• 接着分子カドヘリンを介した内皮細胞間接着の制御機構

  日本学術振興会：科学研究費助成事業

  Date (from‐to) : 1992 -1992 

  Author : 月田 承一郎; 月田 早智子; 永渕 昭良
• 細胞間接着蛋白質と細胞の増殖・転移機構

  日本学術振興会：科学研究費助成事業

  Date (from‐to) : 1992 -1992 

  Author : 月田 承一郎; 米村 重信; 月田 早智子; 永渕 昭良
• Molecular Architecture and Signal Transduction in Cell-to-Cell Adherens Junctions

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 1991 -1992 

  Author : TSUKITA Sachiko
• REGULATION OF CELL ADHESION BY CYTOSKELETON

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 1990 -1992 

  Author : TSUKITA Shoichiro; TANIGUCHI Shunichirou; NISHIMURA Takashi; SHIDA Masato; TSUKITA Sachiko; OWARIBE Katsushi
• 細胞間接着制御蛋白質と細胞の増殖・転移機構

  日本学術振興会：科学研究費助成事業

  Date (from‐to) : 1991 -1991 

  Author : 月田 承一郎; 米村 重信; 月田 早智子; 永渕 昭良
• 細胞癌化における蛋白質リン酸化

  日本学術振興会：科学研究費助成事業

  Date (from‐to) : 1991 -1991 

  Author : 秋山 徹; 西田 栄介; 月田 早智子; 岡田 雅人; 仙波 憲太郎; 小安 重夫
• A New Rapid Freezing Apparatus for Electron Microscopy

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 1990 -1991 

  Author : TSUKITA Shoichiro; TSUKITA Sachiko
• 細胞間ー接着制御蛋白質と細胞の増殖・転移機構

  日本学術振興会：科学研究費助成事業

  Date (from‐to) : 1990 -1990 

  Author : 月田 承一郎; 月田 早智子; 永渕 昭良
• A Rapid-freeze Electron Microscopy in Biological Materials

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 1989 -1990 

  Author : TSUKITA Shoichiro; TSUKITA Sachiko
• Adherens Junction 細胞膜裏打ち細胞骨格

  日本学術振興会：科学研究費助成事業

  Date (from‐to) : 1989 -1989 

  Author : 月田 承一郎; 山梨 裕司; 細谷 浩史; 月田 早智子
• Adherens Junction 細胞膜裏打ち細胞骨格〜pp60^のターゲット蛋白質の検索

  日本学術振興会：科学研究費助成事業

  Date (from‐to) : 1988 -1988 

  Author : 月田 承一郎; 細谷 浩史; 月田 早智子