Hidese Shinsuke

Researcher Information

Affiliation

Clinical Medicine Assistant Professor
Department of Neuropsychiatry Assistant Professor

Degree

• Ph.D. (Medicine)（2018/03）

URL

https://jglobal.jst.go.jp/detail?JGLOBAL_ID=201901002808793367

Research funding number

• 50832763

ORCID ID

•  https://orcid.org/0000-0001-7541-2075

Researcher ID

• AHC-7173-2022

J-Global ID

• 201901002808793367

Profile

• Medical Doctor, Pharmacist, Certified Public Psychologist

Research Interests

• Psychiatry(Clinical Epidemiology, Psychopharmacology, Neuroimaging)   

Research Areas

• Life sciences / Psychiatry
• Life sciences / Cognitive neuroscience
• Other / Other

Academic & Professional Experience

• 2021/04 - Today  Teikyo UniversityTeikyo University Hospital Department of Mental HealthAssistant Professor
• 2018/04 - 2021/03  National Center of Neurology and PsychiatryNational Institute of NeurosciencePostdoctoral Researcher
• 2011/04 - 2014/03  Tokyo Musashino HospitalDepartment of PsychiatryClinical Psychiatrist
• 2010/04 - 2011/03  The University of TokyoFaculty of Medicine University Hospital Department of Neurology and PsychiatryPsychiatric Resident
• 2008/04 - 2010/03  Kyoto UniversityHospital Integrated Clinical Education CenterClinical Resident

Education

• 2014/04 - 2018/03  Tokyo Medical and Dental University  Graduate School of Medical and Dental Sciences  Cognitive and Behavioral Medicine
• 2004/04 - 2008/03  Niigata University  Faculty of Medicine  School of Medicine
• 2002/04 - 2004/03  The University of Tokyo  Graduate School of Pharmaceutical Sciences  Department of Pharmaceutical Technology
• 2000/04 - 2002/03  The University of Tokyo  Faculty of Pharmaceutical Sciences  Department of Pharmacy
• 1998/04 - 2000/03  The University of Tokyo  College of Arts and Sciences  Natural Sciences I

Association Memberships

• Japanese Society of Biological Psychiatry   The Japanese Society of Psychiatry and Neurology   

Research Activity Information

Published Papers

• Genome-wide DNA methylation profiling of blood samples from patients with major depressive disorder: correlation with symptom heterogeneity

  Yukiko Nagao; Mao Fujimoto; Ying Tian; Shinichi Kameyama; Kotaro Hattori; Shinsuke Hidese; Hiroshi Kunugi; Yae Kanai; Eri Arai

  Journal of Psychiatry and Neuroscience 50 (2) E112 - E124 2025/06 [Refereed]
  
• Correlation between myelin basic protein levels in cerebrospinal fluid and motor speed in patients with schizophrenia

  Takako Enokida; Kotaro Hattori; Miho Ota; Megumi Tatsumi; Shinsuke Hidese; Noriko Sato; Mikio Hoshino; Hiroshi Kunugi

  Neuropsychopharmacology Reports Wiley 2574-173X 2024/08 [Refereed]
  
• Search for cerebrospinal fluid biomarkers in patients with major psychiatric disorders: Multiplex immunoassay findings and proximity extension assay prospects

  Shinsuke Hidese

  Neuropsychopharmacology Reports 2024/06 [Refereed]
  
• Neuronal autoantibodies in the cerebrospinal fluid of 148 patients with schizophrenia and 151 healthy controls

  Takako Enokida; Nanako Yoshida; Megumi Tatsumi; Shinsuke Hidese; Yu-ichi Goto; Mikio Hoshino; Hiroshi Kunugi; Kotaro Hattori

  Heliyon Elsevier BV 10 (10) e30695 - e30695 2405-8440 2024/05 [Refereed]
  
• Association of sugary drinks, carbonated beverages, vegetable and fruit juices, sweetened and black coffee, and green tea with subsequent depression: a five-year cohort study

  Zui Narita; Shinsuke Hidese; Rieko Kanehara; Hisateru Tachimori; Hiroaki Hori; Yoshiharu Kim; Hiroshi Kunugi; Kazuhiko Arima; Satoshi Mizukami; Kozo Tanno; Nobuyuki Takanashi; Kazumasa Yamagishi; Isao Muraki; Nobufumi Yasuda; Isao Saito; Koutatsu Maruyama; Taiki Yamaji; Motoki Iwasaki; Manami Inoue; Shoichiro Tsugane; Norie Sawada

  Clinical Nutrition Elsevier BV 0261-5614 2024/04 [Refereed]
  
• Editorial: Clinical guidelines in schizophrenia: applications and evaluation

  Shinsuke Hidese; Signe Düring; Rafael Penadés

  Frontiers in Psychiatry Frontiers Media SA 14 2023/08 [Refereed][Invited]
  
• Reduced homovanillic acid, SDF-1α and SCGF-β levels in cerebrospinal fluid are related to depressive states in systemic lupus erythematosus

  Yuya Fujita; Shigeru Iwata; Shinsuke Hidese; Sayuri Ishiwata; Satoru Ide; Hiroaki Tanaka; Koshiro Sonomoto; Yusuke Miyazaki; Shingo Nakayamada; Atsuko Ikenouchi; Kotaro Hattori; Hiroshi Kunugi; Reiji Yoshimura; Yoshiya Tanaka

  Rheumatology Oxford University Press (OUP) 1462-0324 2023/02 [Refereed]
  
• Association between the Pittsburgh sleep quality index and white matter integrity in healthy adults: a whole-brain magnetic resonance imaging study

  Shinsuke Hidese, Miho Ota, Junko Matsuo, Ikki Ishida, Yuuki Yokota, Kotaro Hattori, Yukihito Yomogida, Hiroshi Kunugi

  Sleep and Biological Rhythms Springer Science and Business Media LLC 21 (2) 1479-8425 2023/01 [Refereed]
  
• Plasma neuropeptide levels in patients with schizophrenia, bipolar disorder, or major depressive disorder and healthy controls: A multiplex immunoassay study

  Shinsuke Hidese, Fuyuko Yoshida, Ikki Ishida, Junko Matsuo, Kotaro Hattori, Hiroshi Kunugi

  Neuropsychopharmacology Reports Wiley 43 (1) 2574-173X 2023 [Refereed]
  
• Association of body mass index and its classifications with gray matter volume in individuals with a wide range of body mass index group: A whole-brain magnetic resonance imaging study

  Shinsuke Hidese, Miho Ota, Junko Matsuo, Ikki Ishida, Yuuki Yokota, Kotaro Hattori, Yukihito Yomogida, Hiroshi Kunugi

  Frontiers in Human Neuroscience Frontiers Media SA 16 (926804) 1662-5161 2022/09 [Refereed]
  
• Relationship between Interpersonal Sensitivity Measure score and clinical symptoms in patients with major psychiatric disorders and healthy individuals

  Shinsuke Hidese; Junko Matsuo; Ikki Ishida; Yuuki Yokota; Miho Ota; Kotaro Hattori; Hiroshi Kunugi

  Psychiatry and Clinical Neurosciences Reports Wiley 1 (2) 2769-2558 2022/06 [Refereed]
  
• Association between vascular endothelial growth factor-mediated blood–brain barrier dysfunction and stress-induced depression

  Hitomi Matsuno; Shoko Tsuchimine; Kazunori O’Hashi; Kazuhisa Sakai; Kotaro Hattori; Shinsuke Hidese; Shingo Nakajima; Shuichi Chiba; Aya Yoshimura; Noriko Fukuzato; Mayumi Kando; Megumi Tatsumi; Shintaro Ogawa; Noritaka Ichinohe; Hiroshi Kunugi; Kazuhiro Sohya

  Molecular Psychiatry Springer Science and Business Media LLC 1359-4184 2022/05 [Refereed]
  
• Gut permeability and its clinical relevance in schizophrenia

  Ikki Ishida; Jun Ogura; Emiko Aizawa; Miho Ota; Shinsuke Hidese; Yukihito Yomogida; Junko Matsuo; Sumiko Yoshida; Hiroshi Kunugi

  Neuropsychopharmacology Reports Wiley 42 (1) 70 - 76 2574-173X 2022/01 [Refereed]
  
• The cerebellum as a moderator of negative bias of facial expression processing in depressive patients

  Anna Nakamura; Yukihito Yomogida; Miho Ota; Junko Matsuo; Ikki Ishida; Shinsuke Hidese; Hiroshi Kunugi

  Journal of Affective Disorders Reports Elsevier BV 7 100295 - 100295 2666-9153 2021/12 [Refereed]
  
• Neuroanatomical basis of harm avoidance personality traits in major depressive disorder

  Yukihito Yomogida, Miho Ota, Junko Matsuo, Ikki Ishida, Shinsuke Hidese, Toshiya Teraishi, Noriko Sato, Hiroshi Matsuda, Kotaro Hattori, Hiroshi Kunugi

  Journal of Affective Disorders Reports Elsevier BV 6 100225 - 100225 2666-9153 2021/09 [Refereed]
  
• Effect of Lacticaseibacillus paracasei Strain Shirota on Improvement in Depressive Symptoms, and Its Association with Abundance of Actinobacteria in Gut Microbiota

  Machiko Otaka; Hiroko Kikuchi-Hayakawa; Jun Ogura; Hiroshi Ishikawa; Yukihito Yomogida; Miho Ota; Shinsuke Hidese; Ikki Ishida; Masanori Aida; Kazunori Matsuda; Mitsuhisa Kawai; Sumiko Yoshida; Hiroshi Kunugi

  Microorganisms MDPI AG 9 (5) 1026 - 1026 2021/05 [Refereed]
  
• Profiling of Cerebrospinal Fluid Lipids and Their Relationship with Plasma Lipids in Healthy Humans

  Kosuke Saito; Kotaro Hattori; Shinsuke Hidese; Daimei Sasayama; Tomoko Miyakawa; Ryo Matsumura; Megumi Tatsumi; Yuuki Yokota; Miho Ota; Hiroaki Hori; Hiroshi Kunugi

  Metabolites MDPI AG 11 (5) 268 - 268 2021/04 [Refereed]
  
• Cerebrospinal Fluid Inflammatory Cytokine Levels in Patients With Major Psychiatric Disorders: A Multiplex Immunoassay Study

  Shinsuke Hidese; Kotaro Hattori; Daimei Sasayama; Takuya Tsumagari; Tomoko Miyakawa; Ryo Matsumura; Yuuki Yokota; Ikki Ishida; Junko Matsuo; Sumiko Yoshida; Miho Ota; Hiroshi Kunugi

  Frontiers in Pharmacology Frontiers Media SA 11 594394 - 594394 2021/02 [Refereed]
  
• Performance on the Wechsler Adult Intelligence Scale ( WAIS ) in Japanese patients with bipolar and major depressive disorders in euthymic and depressed states

  Junko Matsuo; Hiroaki Hori; Ikki Ishida; Moeko Hiraishi; Miho Ota; Shinsuke Hidese; Yukihito Yomogida; Hiroshi Kunugi

  Psychiatry and Clinical Neurosciences Wiley 75 (4) 128 - 137 1323-1316 2020/12 [Refereed]
  
• Structural brain network differences in bipolar disorder using with similarity-based approach

  Miho Ota; Takamasa Noda; Noriko Sato; Shinsuke Hidese; Toshiya Teraishi; Hiroshi Matsuda; Hiroshi Kunugi

  Acta Neuropsychiatrica Cambridge University Press (CUP) 33 (3) 1 - 26 0924-2708 2020/12 [Refereed]
  
• Cerebrospinal fluid neuroplasticity-associated protein levels in patients with psychiatric disorders: a multiplex immunoassay study

  Shinsuke Hidese; Kotaro Hattori; Daimei Sasayama; Takuya Tsumagari; Tomoko Miyakawa; Ryo Matsumura; Yuuki Yokota; Ikki Ishida; Junko Matsuo; Sumiko Yoshida; Miho Ota; Hiroshi Kunugi

  Translational Psychiatry Springer Science and Business Media LLC 10 (1) 161 - 161 2020/12 [Refereed]
  
• Association between obesity and white matter microstructure impairments in patients with schizophrenia: A whole-brain magnetic resonance imaging study

  Shinsuke Hidese; Miho Ota; Junko Matsuo; Ikki Ishida; Yuuki Yokota; Kotaro Hattori; Yukihito Yomogida; Hiroshi Kunugi

  Schizophrenia Research Elsevier BV 230 108 - 110 0920-9964 2020/08 [Refereed]
  
• Lower cerebrospinal fluid CRH concentration in chronic schizophrenia with negative symptoms

  Sayuri Ishiwata; Kotaro Hattori; Shinsuke Hidese; Daimei Sasayama; Tomoko Miyakawa; Ryo Matsumura; Yuuki Yokota; Sumiko Yoshida; Hiroshi Kunugi

  Journal of Psychiatric Research Elsevier BV 127 13 - 19 0022-3956 2020/08 [Refereed]
  
• Correlation Between the Wechsler Adult Intelligence Scale- 3rd Edition Metrics and Brain Structure in Healthy Individuals: A Whole-Brain Magnetic Resonance Imaging Study

  Shinsuke Hidese; Miho Ota; Junko Matsuo; Ikki Ishida; Moeko Hiraishi; Yuuki Yokota; Kotaro Hattori; Yukihito Yomogida; Hiroshi Kunugi

  Frontiers in Human Neuroscience Frontiers Media SA 14 2020/06 [Refereed]
  
• Possible associations between plasma fibroblast growth factor 21 levels and cognition in bipolar disorder

  Favour Omileke; Sayuri Ishiwata; Junko Matsuo; Fuyuko Yoshida; Shinsuke Hidese; Kotaro Hattori; Hiroshi Kunugi

  Neuropsychopharmacology Reports Wiley 40 (2) 175 - 181 2574-173X 2020/06 [Refereed]
  
• Characterization of Postprandial Effects on CSF Metabolomics: A Pilot Study with Parallel Comparison to Plasma

  Kosuke Saito; Kotaro Hattori; Tomohiro Andou; Yoshinori Satomi; Masamitsu Gotou; Hiroyuki Kobayashi; Shinsuke Hidese; Hiroshi Kunugi

  Metabolites MDPI AG 10 (5) 185 - 185 2020/05 [Refereed]
  
• Altered ethanolamine plasmalogen and phosphatidylethanolamine levels in blood plasma of patients with bipolar disorder

  Shintaro Ogawa; Kotaro Hattori; Miho Ota; Shinsuke Hidese; Tomoko Miyakawa; Ryo Matsumura; Yuuki Yokota; Ikki Ishida; Junko Matsuo; Sumiko Yoshida; Yasuyo Yamazaki; Dayan Goodenowe; Hiroshi Kunugi

  Psychiatry and Clinical Neurosciences Wiley 74 (3) 204 - 210 1323-1316 2020/03 [Refereed]
  
• Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial

  Shinsuke Hidese; Sintaro Ogawa; Miho Ota; Ikki Ishida; Zenta Yasukawa; Makoto Ozeki; Hiroshi Kunugi

  Nutrients MDPI AG 11 (10) 2362 - 2362 2019/10 [Refereed]
  

• Reduced plasma orexin-A levels in patients with bipolar disorder

  Shoko Tsuchimine; Kotaro Hattori; Miho Ota; Shinsuke Hidese; Toshiya Teraishi; Daimei Sasayama; Hiroaki Hori; Takamasa Noda; Sumiko Yoshida; Fuyuko Yoshida; Hiroshi Kunugi

  Neuropsychiatric Disease and Treatment Informa UK Limited Volume 15 2221 - 2230 2019/08 [Refereed]
  
• Cerebrospinal fluid BDNF pro-peptide levels in major depressive disorder and schizophrenia

  Toshiyuki Mizui; Kotaro Hattori; Sayuri Ishiwata; Shinsuke Hidese; Sumiko Yoshida; Hiroshi Kunugi; Masami Kojima

  Journal of Psychiatric Research Elsevier BV 113 190 - 198 0022-3956 2019/06 [Refereed]
  
• A polymorphism of the methylenetetrahydrofolate reductase gene confers susceptibility to schizophrenia and related brain changes

  Miho Ota; Noriko Sato; Fuyuko Yoshida; Kotaro Hattori; Shinsuke Hidese; Toshiya Teraishi; Hiroshi Kunugi

  Schizophrenia Research Elsevier BV 208 462 - 464 0920-9964 2019/06 [Refereed]
  
• The use of diffusional kurtosis imaging and neurite orientation dispersion and density imaging of the brain in bipolar disorder

  Miho Ota; Takamasa Noda; Noriko Sato; Shinsuke Hidese; Toshiya Teraishi; Shiori Setoyama; Hiroshi Matsuda; Hiroshi Kunugi

  Journal of Affective Disorders Elsevier BV 251 231 - 234 0165-0327 2019/05 [Refereed]
  
• Association between lower estimated premorbid intelligence quotient and smoking behavior in patients with schizophrenia

  Shinsuke Hidese; Junko Matsuo; Ikki Ishida; Moeko Hiraishi; Toshiya Teraishi; Miho Ota; Kotaro Hattori; Hiroshi Kunugi

  Schizophrenia Research: Cognition Elsevier BV 15 7 - 13 2215-0013 2019/03 [Refereed]
  
• Food allergy is associated with depression and psychological distress: A web-based study in 11,876 Japanese

  Shinsuke Hidese; Shun Nogawa; Kenji Saito; Hiroshi Kunugi

  Journal of Affective Disorders Elsevier BV 245 213 - 218 0165-0327 2019/02 [Refereed]
  
• The relationship between the Wechsler Memory Scale-Revised scores and whole-brain structure in patients with schizophrenia and healthy individuals

  Shinsuke Hidese; Miho Ota; Hiroaki Hori; Junko Matsuo; Ikki Ishida; Moeko Hiraishi; Toshiya Teraishi; Kotaro Hattori; Hiroshi Kunugi

  Cognitive Neuropsychiatry Informa UK Limited 24 (1) 80 - 91 1354-6805 2019/01 [Refereed]
  
• Association between the scores of the Japanese version of the Brief Assessment of Cognition in Schizophrenia and whole-brain structure in patients with chronic schizophrenia: a voxel-based morphometry and diffusion tensor imaging study.

  Shinsuke Hidese; Miho Ota; Junko Matsuo; Ikki Ishida; Moeko Hiraishi; Toshiya Teraishi; Kotaro Hattori; Hiroshi Kunugi

  Psychiatria et neurologia Japonica 120 (12) 1055 - 1059 2018/12 [Refereed][Invited]
  
• Association between iron-deficiency anemia and depression: A web-based Japanese investigation

  Shinsuke Hidese; Kenji Saito; Shinya Asano; Hiroshi Kunugi

  Psychiatry and Clinical Neurosciences Wiley 72 (7) 513 - 521 1323-1316 2018/07 [Refereed]
  
• Association of depression with body mass index classification, metabolic disease, and lifestyle: A web-based survey involving 11,876 Japanese people

  Shinsuke Hidese; Shinya Asano; Kenji Saito; Daimei Sasayama; Hiroshi Kunugi

  Journal of Psychiatric Research Elsevier BV 102 23 - 28 0022-3956 2018/07 [Refereed]
  
  ダウンロード
• Manual dexterity and brain structure in patients with schizophrenia: A whole-brain magnetic resonance imaging study

  Shinsuke Hidese; Miho Ota; Daimei Sasayama; Junko Matsuo; Ikki Ishida; Moeko Hiraishi; Toshiya Teraishi; Kotaro Hattori; Hiroshi Kunugi

  Psychiatry Research: Neuroimaging Elsevier BV 276 9 - 14 0925-4927 2018/06 [Refereed]
  
• Relationship of Handgrip Strength and Body Mass Index With Cognitive Function in Patients With Schizophrenia

  Shinsuke Hidese; Junko Matsuo; Ikki Ishida; Moeko Hiraishi; Toshiya Teraishi; Miho Ota; Kotaro Hattori; Hiroshi Kunugi

  Frontiers in Psychiatry Frontiers Media SA 9 156 - 156 2018/04 [Refereed]
  
• Sensorimotor Gating in Depressed and Euthymic Patients with Bipolar Disorder: Analysis on Prepulse Inhibition of Acoustic Startle Response Stratified by Gender and State

  Junko Matsuo; Miho Ota; Shinsuke Hidese; Toshiya Teraishi; Hiroaki Hori; Ikki Ishida; Moeko Hiraishi; Hiroshi Kunugi

  Frontiers in Psychiatry Frontiers Media SA 9 123 - 123 2018/04 [Refereed]
  
• 13 C-phenylalanine breath test and serum biopterin in schizophrenia, bipolar disorder and major depressive disorder

  Toshiya Teraishi; Masahiro Kajiwara; Hiroaki Hori; Daimei Sasayama; Shinsuke Hidese; Junko Matsuo; Ikki Ishida; Yasuhiro Kajiwara; Yuji Ozeki; Miho Ota; Kotaro Hattori; Teruhiko Higuchi; Hiroshi Kunugi

  Journal of Psychiatric Research Elsevier BV 99 142 - 150 0022-3956 2018/04 [Refereed]
  
• The use of diffusional kurtosis imaging and neurite orientation dispersion and density imaging of the brain in major depressive disorder

  Miho Ota; Takamasa Noda; Noriko Sato; Shinsuke Hidese; Toshiya Teraishi; Shiori Setoyama; Daichi Sone; Hiroshi Matsuda; Hiroshi Kunugi

  Journal of Psychiatric Research Elsevier BV 98 22 - 29 0022-3956 2018/03 [Refereed]
  
• Increased cerebrospinal fluid complement C5 levels in major depressive disorder and schizophrenia

  Takashi Ishii; Kotaro Hattori; Tomoko Miyakawa; Kentaro Watanabe; Shinsuke Hidese; Daimei Sasayama; Miho Ota; Toshiya Teraishi; Hiroaki Hori; Sumiko Yoshida; Akihiko Nunomura; Kazuyuki Nakagome; Hiroshi Kunugi

  Biochemical and Biophysical Research Communications Elsevier BV 497 (2) 683 - 688 0006-291X 2018/03 [Refereed]
  
• Association of obesity with cognitive function and brain structure in patients with major depressive disorder

  Shinsuke Hidese; Miho Ota; Junko Matsuo; Ikki Ishida; Moeko Hiraishi; Sumiko Yoshida; Takamasa Noda; Noriko Sato; Toshiya Teraishi; Kotaro Hattori; Hiroshi Kunugi

  Journal of Affective Disorders Elsevier BV 225 188 - 194 0165-0327 2018/01 [Refereed]
  
  ダウンロード
• Association between the scores of the Japanese version of the Brief Assessment of Cognition in Schizophrenia and whole-brain structure in patients with chronic schizophrenia: A voxel-based morphometry and diffusion tensor imaging study

  Shinsuke Hidese, Miho Ota, Junko Matsuo, Ikki Ishida, Moeko Hiraishi, Toshiya Teraishi, Kotaro Hattori, Hiroshi Kunugi

  Psychiatry and Clinical Neurosciences Wiley 71 (12) 826 - 835 1440-1819 2017/12 [Refereed]
  
• Cerebrospinal fluid neural cell adhesion molecule levels and their correlation with clinical variables in patients with schizophrenia, bipolar disorder, and major depressive disorder

  Shinsuke Hidese; Kotaro Hattori; Daimei Sasayama; Tomoko Miyakawa; Ryo Matsumura; Yuuki Yokota; Ikki Ishida; Junko Matsuo; Takamasa Noda; Sumiko Yoshida; Toshiya Teraishi; Hiroaki Hori; Miho Ota; Hiroshi Kunugi

  Progress in Neuro-Psychopharmacology and Biological Psychiatry Elsevier BV 76 12 - 18 0278-5846 2017/06 [Refereed]
  
• Effects of chronic l-theanine administration in patients with major depressive disorder: an open-label study

  Shinsuke Hidese; Miho Ota; Chisato Wakabayashi; Takamasa Noda; Hayato Ozawa; Tsutomu Okubo; Hiroshi Kunugi

  Acta Neuropsychiatrica Cambridge University Press (CUP) 29 (2) 72 - 79 0924-2708 2017/04 [Refereed]
  
• Sexually dimorphic deficits of prepulse inhibition in patients with major depressive disorder and their relationship to symptoms: A large single ethnicity study

  Junko Matsuo, Miho Ota, Shinsuke Hidese, Hiroaki Hori, Toshiya Teraishi, Ikki Ishida, Moeko Hiraishi, Hiroshi Kunugi

  Journal of Affective Disorders Elsevier BV 211 75 - 82 1573-2517 2017/03 [Refereed]
  
• Structural differences in hippocampal subfields among schizophrenia patients, major depressive disorder patients, and healthy subjects

  Miho Ota; Noriko Sato; Shinsuke Hidese; Toshiya Teraishi; Norihide Maikusa; Hiroshi Matsuda; Kotaro Hattori; Hiroshi Kunugi

  Psychiatry Research: Neuroimaging Elsevier BV 259 54 - 59 0925-4927 2017/01 [Refereed]
  
• A large single ethnicity study of prepulse inhibition in schizophrenia: Separate analysis by sex focusing on effect of symptoms

  Junko Matsuo, Miho Ota, Hiroaki Hori, Shinsuke Hidese, Toshiya Teraishi, Ikki Ishida, Moeko Hiraishi, Hiroshi Kunugi

  Journal of Psychiatric Research Elsevier BV 82 155 - 162 1879-1379 2016/11 [Refereed]
  
• 24-h activity rhythm and sleep in depressed outpatients

  Hiroaki Hori, Norie Koga, Shinsuke Hidese, Anna Nagashima, Yoshiharu Kim, Teruhiko Higuchi, Hiroshi Kunugi

  Journal of Psychiatric Research Elsevier BV 77 27 - 34 1879-1379 2016/06 [Refereed]
  
• Psychotropic effects of a green tea ingredient, L─ theaine

  Hiroshi Kunugi, Miho Ota, Chisato, Wakabayashi, Shinsuke Hidese, Hayato Ozawa, Tsutomu Okubo

  Japanese Journal of Biological Psychiatry 日本生物学的精神医学会 ; 2010- 27 (4) 177 - 181 2186-6619 2016 [Refereed]
  

Conference Activities & Talks

• An open-label clinical study of chronic L-theanine supplementation in patients with major depressive disorder.

  Shinsuke Hidese; Miho Ota; Hayato Ozawa; Tsutomu Okubo; Hiroshi Kunugi

  Nutrition 2019  2019/06
• A web-based survey for the association between food allergy and depression/psychological distress in 11,876 Japanese

  Shinsuke Hidese; Shun Nogawa; Kenji Saito; Hiroshi Kunugi

  Nutrition 2019  2019/06
• Association of obesity with cognitive function and brain structure in patients with major depressive disorder

  Shinsuke Hidese; Miho Ota; Junko Matsuo; Ikki Ishida; Moeko Hiraishi; Sumiko Yoshida; Takamasa Noda; Noriko Sato; Toshiya Teraishi; Kotaro Hattori; Hiroshi Kunugi

  39th Annual Meeting of Japanese Society of Biological Psychiatry  2017/09
• Effects of chronic L-theanine administration in patients with major depressive disorder: an open-label study

  Shinsuke Hidese; Miho Ota; Chisato Wakabayashi; Takamasa Noda; Hayato Ozawa; Tsutomu Okubo; Hiroshi Kunugi

  46th Annual Meeting of the Japanese Society of Neuropsychopharmacology  2016/07
• A case of senile psychiatric disorder in which refusal of eating had been presented for a long time and dementia was differentiated on the clinical course.

  Shinsuke Hidese

  110th Annual Meeting of the Japasene Society of Psychiatry and Neurology  2014/06
• The Historiographical Intersection of Psychiatry and Cognitive Science: In the Genealogy of Science and Philosophy

  Shinsuke Hidese

  The 17th Japanese Society for the History of Psychiatry Academic Conference  2013/11

MISC

• A case of usefulness of cerebrospinal fluid testing in the diagnosis of Alzheimer's disease type

  Taneda Sho, Akahane Akihisa, Watanabe Kimiaki, Kanata Sho, Hidese Shinsuke, Sato Kenichi, Kunugi Hiroshi  精神神経学雑誌  125-  (1)  85  -85  2023/01
• Collaboration and cooperation with physical physicians and other professions regarding mental illness management Initiatives for diagnosis and treatment of SLE with neuropsychiatric symptoms (NPSLE) through cooperation between medical departments

  Shigeru Iwata; Yuya Fujita; Shinsuke Hidese; Sayuri Ishiwata; Kotaro Hattori; Atsuko Ikenouchi; Hiroshi Kunugi; Reiji Yoshimura; Yoshiya Tanaka  精神神経学雑誌  124-  (4付録)  S  -657  2022/04
• A case of Wernicke-Korsakoff syndrome (WKS) with improved ADL and cognitive function after taking Goshajinkigan for defecation disorder

  Nomura Yoshiko, Hidese Shinsuke, Kanai Rie, Oshikubo Gaku, Watanabe Yukako, Akahane Akihisa, Tochigi Mamoru, Kunugi Hiroshi  精神神経学雑誌  124-  (4付録)  S  -388  2022/04
• A multiplex immunoassay study for cerebrospinal fluid neuroplasticity-associated protein levels in patients with psychiatric disorders

  Shinsuke Hidese  Medical Science Digest  46-  (6)  348  -349  2020/06  [Invited]
  
• Multiple Psychotropic Effects of L-theanine

  Shinsuke Hidese; Hiroshi Kunugi  ILSI Japan  142-  9  -16  2020/05  [Invited]
  
• A Web-based Survey for the Association Between Food Allergy and Depression/psychological Distress in 11,876 Japanese (P18-019-19)

  Shinsuke Hidese; Shun Nogawa; Kenji Saito; Hiroshi Kunugi  Current Developments in Nutrition  3-  (Supplement_1)  2019/06
• An Open-label Clinical Study of Chronic L-theanine Supplementation in Patients with Major Depressive Disorder (P12-007-19)

  Shinsuke Hidese; Miho Ota; Hayato Ozawa; Tsutomu Okubo; Hiroshi Kunugi  Current Developments in Nutrition  3-  (Supplement_1)  2019/06

Industrial Property Rights

• 特許7356676:Cognitive Function Improving Component  

  Zenta Yasukawa, Makoto Ozeki, Hiroshi Kunugi, Shinsuke Hidese

Awards & Honors

• 2024 NPPR Article Award
   Plasma neuropeptide levels in patients with schizophrenia, bipolar disorder, or major depressive disorder and healthy controls: A multiplex immunoassay study

Research Grants & Projects

• Proteomic exploration of neuromarkers in cerebrospinal fluid of patients with major psychiatric disorders

  SENSHIN Medical Research Foundation：Psychiatric Treament Grant 24 General 1-56

  Date (from‐to) : 2024/12 -2025/11 

  Author : Shinsuke Hidese
• Examination of the role of neuropeptides in the pathology of psychiatric disorders

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)

  Date (from‐to) : 2021/04 -2024/03 

  Author : Shinsuke Hidese
• Research on molecular and brain basis for sensorimotor gating dysfunction

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)

  Date (from‐to) : 2019/04 -2022/03 

  Author : Matsuo Junko
• Multiplex immunoassay for cerebrospinal fluid neuroplasticity-associated protein levels in patients with psychiaric disorders

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research Grant-in-Aid for Early-Career Scientists

  Date (from‐to) : 2019/04 -2021/03 

  Author : Shinsuke Hidese
• Comprehensive analysis of neuroplasticity-associated proteins in cerebrospinal fluid of patients with psychiatric disorders

  SENSHIN Medical Research Foundation：Psychiatric Treament Grant 18 General 2-15

  Date (from‐to) : 2018/12 -2019/11 

  Author : Shinsuke Hidese

Teaching Experience

Lectures on Psychiatry (Schizophrenia)Lectures on Psychiatry (Schizophrenia) Department of Nursing, Faculty of Medical Technology, Teikyo University
Lectures on Psychiatry (Structure and Function of the Brain)Lectures on Psychiatry (Structure and Function of the Brain) Department of Nursing, Faculty of Medical Technology, Teikyo University
Introduction to Mental Disorders (Schizophrenia)Introduction to Mental Disorders (Schizophrenia) Department of Orthoptics, Faculty of Medical Technology, Teikyo University
Diagnosis/Treatment of SchizophreniaDiagnosis/Treatment of Schizophrenia Graduate School of Medicine, Teikyo University
Law and PsychiatryLaw and Psychiatry Department of Medicine, School of Medicine,Teikyo University
Mental and psychosomatic disorders that tend to appear at each developmental stage, Personality disorders Epilepsy Neurodevelopmental disorders etc., Pathogenesis, symptoms, diagnosis, and treatmentMental and psychosomatic disorders that tend to appear at each developmental stage, Personality disorders Epilepsy Neurodevelopmental disorders etc., Pathogenesis, symptoms, diagnosis, and treatment Teikyo College of Nursing
What is mental illness?, Psychiatric symptomatology and condition profile, Diagnosis and classification of mental disorders, treatment and examinationWhat is mental illness?, Psychiatric symptomatology and condition profile, Diagnosis and classification of mental disorders, treatment and examination Teikyo College of Nursing
Pathology/Symptom/Diagnosis/Treatment of Personality Disorders, Epilepsy, and Neurodevelopmental DisordersPathology/Symptom/Diagnosis/Treatment of Personality Disorders, Epilepsy, and Neurodevelopmental Disorders Teikyo College of Nursing
Pathology/Symptom/Diagnosis/Treatment of Neurotic Disorders, Stress-related Disorders, and Somatic Symptom DisordersPathology/Symptom/Diagnosis/Treatment of Neurotic Disorders, Stress-related Disorders, and Somatic Symptom Disorders Teikyo College of Nursing

Social Contribution

• Basic Knowledge of Workplace Mental Health

  Date (from-to) : 2016/10/26

  Category : Lecture

  Sponser, Organizer, Publisher  : Tokyo Metropolitan Higashiyamato Medical Center

  Event, Program, Title : Mental Health Care Workshop

Media Coverage

• Decreased cerebrospinal fluid NCAM and its correlation with symptoms in bipolar disorder

  Date : 2017/04/18

  Writer: Myself

  Publisher, broadcasting station: Bipolar Disorder Research Network Japan

  Volume 72 Pr

Academic Contribution

• Decreased cerebrospinal fluid NCAM-120 levels and associated brain morphological changes in patients with major depressive disorder

  Date (from-to) :2015/09/04

  Type: Academic society etc

  Organizer, responsible person: The 34th Forum on the Pharmacology and Biochemistry of Manic-Depressive Illness

Others

• 2017/02 Tokyo Regional Correction Headquarters Superintendent Certificate of Thanks